Stephen M Hedrick - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Cell Biology
Website:
https://biology.ucsd.edu/research/faculty/shedrick

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chandra S, Ascui G, Riffelmacher T, Chawla A, Ramírez-Suástegui C, Castelan VC, Seumois G, Simon H, Murray MP, Seo GY, Premlal ALR, Schmiedel B, Verstichel G, Li Y, Lin CH, ... ... Hedrick SM, et al. Transcriptomes and metabolism define mouse and human MAIT cell populations. Science Immunology. 8: eabn8531. PMID 37948512 DOI: 10.1126/sciimmunol.abn8531  0.38
2022 Lai CY, Marcel N, Yaldiko AW, Delpoux A, Hedrick SM. A Intronic Element Regulates T Follicular Helper Cell Differentiation. Journal of Immunology (Baltimore, Md. : 1950). PMID 35948398 DOI: 10.4049/jimmunol.2100777  0.514
2021 Milner JJ, Toma C, Quon S, Omilusik K, Scharping NE, Dey A, Reina-Campos M, Nguyen H, Getzler AJ, Diao H, Yu B, Delpoux A, Yoshida TM, Li D, Qi J, ... ... Hedrick SM, et al. Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection. The Journal of Experimental Medicine. 218. PMID 34037670 DOI: 10.1084/jem.20202512  0.503
2021 Delpoux A, Marcel N, Hess Michelini R, Katayama CD, Allison KA, Glass CK, Quiñones-Parra SM, Murre C, Loh L, Kedzierska K, Lappas M, Hedrick SM, Doedens AL. FOXO1 constrains activation and regulates senescence in CD8 T cells. Cell Reports. 34: 108674. PMID 33503413 DOI: 10.1016/j.celrep.2020.108674  0.491
2020 Milner JJ, Nguyen H, Omilusik K, Reina-Campos M, Tsai M, Toma C, Delpoux A, Boland BS, Hedrick SM, Chang JT, Goldrath AW. Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population. Proceedings of the National Academy of Sciences of the United States of America. PMID 32978300 DOI: 10.1073/pnas.2008571117  0.358
2020 Reynaud CA, Hedrick SM. Editorial overview: Lymphocyte effector subsets: blurring the frontiers. Current Opinion in Immunology. 63: iii-v. PMID 32359520 DOI: 10.1016/J.Coi.2020.04.001  0.427
2020 Marcel N, Hedrick SM. A key control point in the T cell response to chronic infection and neoplasia: FOXO1. Current Opinion in Immunology. 63: 51-60. PMID 32135399 DOI: 10.1016/J.Coi.2020.02.001  0.559
2018 Utzschneider DT, Delpoux A, Wieland D, Huang X, Lai CY, Hofmann M, Thimme R, Hedrick SM. Active Maintenance of T Cell Memory in Acute and Chronic Viral Infection Depends on Continuous Expression of FOXO1. Cell Reports. 22: 3454-3467. PMID 29590615 DOI: 10.1016/J.Celrep.2018.03.020  0.395
2018 Tsau JS, Huang X, Lai CY, Hedrick SM. The Effects of Dendritic Cell Hypersensitivity on Persistent Viral Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29311359 DOI: 10.4049/Jimmunol.1601870  0.556
2017 Delpoux A, Michelini RH, Verma S, Lai CY, Omilusik KD, Utzschneider DT, Redwood AJ, Goldrath AW, Benedict CA, Hedrick SM. Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells. The Journal of Experimental Medicine. PMID 29282254 DOI: 10.1084/Jem.20170697  0.562
2017 Delpoux A, Lai CY, Hedrick SM, Doedens AL. FOXO1 opposition of CD8(+) T cell effector programming confers early memory properties and phenotypic diversity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973925 DOI: 10.1073/Pnas.1618916114  0.453
2017 Hedrick S, Sprent J. Charles D. Surh 1961–2017 Immunity. 47: 1005-1006. DOI: 10.1016/J.Immuni.2017.11.017  0.493
2016 Stienne C, Michieletto MF, Benamar M, Carrié N, Bernard I, Nguyen XH, Lippi Y, Duguet F, Liblau RS, Hedrick SM, Saoudi A, Dejean AS. Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes. Immunity. PMID 27742544 DOI: 10.1016/J.Immuni.2016.09.010  0.599
2016 Allison KA, Sajti E, Collier JG, Gosselin D, Troutman TD, Stone EL, Hedrick SM, Glass CK. Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells. Elife. 5. PMID 27376549 DOI: 10.7554/Elife.10134  0.574
2016 Allison KA, Sajti E, Collier JG, Gosselin D, Troutman TD, Stone EL, Hedrick SM, Glass CK. Author response: Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells Elife. DOI: 10.7554/Elife.10134.050  0.482
2015 Mah IK, Soloff R, Hedrick SM, Mariani FV. Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway. Stem Cell Reports. PMID 26527382 DOI: 10.1016/J.Stemcr.2015.09.021  0.357
2015 Kang H, Corr M, Mansson R, Welinder E, Hedrick SM, Stone EL. Loss of Murine FOXO3 in Cells of the Myeloid Lineage Enhances Myelopoiesis but Protects from K/BxN-Serum Transfer-Induced Arthritis. Plos One. 10: e0126728. PMID 25969990 DOI: 10.1371/Journal.Pone.0126728  0.406
2015 Stone EL, Pepper M, Katayama CD, Kerdiles YM, Lai CY, Emslie E, Lin YC, Yang E, Goldrath AW, Li MO, Cantrell DA, Hedrick SM. ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation. Immunity. 42: 239-51. PMID 25692700 DOI: 10.1016/J.Immuni.2015.01.017  0.526
2014 Lee SY, Coffey F, Fahl SP, Peri S, Rhodes M, Cai KQ, Carleton M, Hedrick SM, Fehling HJ, Zúñiga-Pflücker JC, Kappes DJ, Wiest DL. Noncanonical mode of ERK action controls alternative αβ and γδ T cell lineage fates. Immunity. 41: 934-46. PMID 25526308 DOI: 10.1016/J.Immuni.2014.10.021  0.444
2014 Mingueneau M, Krishnaswamy S, Spitzer MH, Bendall SC, Stone EL, Hedrick SM, Pe'er D, Mathis D, Nolan GP, Benoist C. Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 16466-71. PMID 25362052 DOI: 10.1073/Pnas.1419337111  0.526
2014 Cuda CM, Misharin AV, Gierut AK, Saber R, Haines GK, Hutcheson J, Hedrick SM, Mohan C, Budinger GS, Stehlik C, Perlman H. Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation. Journal of Immunology (Baltimore, Md. : 1950). 192: 5548-60. PMID 24808358 DOI: 10.4049/Jimmunol.1400122  0.419
2013 Hess Michelini R, Doedens AL, Goldrath AW, Hedrick SM. Differentiation of CD8 memory T cells depends on Foxo1. The Journal of Experimental Medicine. 210: 1189-200. PMID 23712431 DOI: 10.1084/Jem.20130392  0.555
2013 Ruff LE, Mahmoud EA, Sankaranarayanan J, Morachis JM, Katayama CD, Corr M, Hedrick SM, Almutairi A. Antigen-loaded pH-sensitive hydrogel microparticles are taken up by dendritic cells with no requirement for targeting antibodies. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 195-203. PMID 23060228 DOI: 10.1039/C2Ib20109G  0.771
2013 Jenkins MK, Hedrick SM. Leo Lefrançois (1956–2013) Immunity. 39: 415-416. DOI: 10.1016/J.Immuni.2013.08.030  0.727
2012 Hedrick SM, Hess Michelini R, Doedens AL, Goldrath AW, Stone EL. FOXO transcription factors throughout T cell biology. Nature Reviews. Immunology. 12: 649-61. PMID 22918467 DOI: 10.1038/Nri3278  0.412
2012 Gu L, Ruff LE, Qin Z, Corr M, Hedrick SM, Sailor MJ. Multivalent porous silicon nanoparticles enhance the immune activation potency of agonistic CD40 antibody. Advanced Materials (Deerfield Beach, Fla.). 24: 3981-7. PMID 22689074 DOI: 10.1002/Adma.201200776  0.746
2012 Chang CF, D'Souza WN, Ch'en IL, Pages G, Pouyssegur J, Hedrick SM. Polar opposites: Erk direction of CD4 T cell subsets. Journal of Immunology (Baltimore, Md. : 1950). 189: 721-31. PMID 22675204 DOI: 10.4049/Jimmunol.1103015  0.804
2012 Hedrick SM. Positive selection in the thymus: an enigma wrapped in a mystery. Journal of Immunology (Baltimore, Md. : 1950). 188: 2043-5. PMID 22345700 DOI: 10.4049/Jimmunol.1200077  0.399
2012 Gu L, Ruff LE, Qin Z, Corr M, Hedrick SM, Sailor MJ. Nanoparticles for Imunotherapy: Multivalent Porous Silicon Nanoparticles Enhance the Immune Activation Potency of Agonistic CD40 Antibody (Adv. Mater. 29/2012) Advanced Materials. 24: 4025-4025. DOI: 10.1002/Adma.201290177  0.732
2011 Günther C, Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H, Waldner MJ, Hedrick SM, Tenzer S, Neurath MF, Becker C. Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis. Nature. 477: 335-9. PMID 21921917 DOI: 10.1038/Nature10400  0.437
2011 Ch'en IL, Tsau JS, Molkentin JD, Komatsu M, Hedrick SM. Mechanisms of necroptosis in T cells. The Journal of Experimental Medicine. 208: 633-41. PMID 21402742 DOI: 10.1084/Jem.20110251  0.575
2011 Dejean AS, Hedrick SM, Kerdiles YM. Highly specialized role of Forkhead box O transcription factors in the immune system. Antioxidants & Redox Signaling. 14: 663-74. PMID 20673126 DOI: 10.1089/Ars.2010.3414  0.406
2010 Kerdiles YM, Stone EL, Beisner DR, Beisner DL, McGargill MA, Ch'en IL, Stockmann C, Katayama CD, Hedrick SM. Foxo transcription factors control regulatory T cell development and function. Immunity. 33: 890-904. PMID 21167754 DOI: 10.1016/J.Immuni.2010.12.002  0.833
2010 Hedrick SM, Ch'en IL, Alves BN. Intertwined pathways of programmed cell death in immunity. Immunological Reviews. 236: 41-53. PMID 20636807 DOI: 10.1111/J.1600-065X.2010.00918.X  0.37
2010 Soto PC, Stein LL, Hurtado-Ziola N, Hedrick SM, Varki A. Relative over-reactivity of human versus chimpanzee lymphocytes: implications for the human diseases associated with immune activation. Journal of Immunology (Baltimore, Md. : 1950). 184: 4185-95. PMID 20231688 DOI: 10.4049/Jimmunol.0903420  0.425
2009 McGargill MA, Ch'en IL, Katayama CD, Pagès G, Pouysségur J, Hedrick SM. Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 4838-42. PMID 19801509 DOI: 10.4049/Jimmunol.0902208  0.457
2009 Hedrick SM. The cunning little vixen: Foxo and the cycle of life and death. Nature Immunology. 10: 1057-63. PMID 19701188 DOI: 10.1038/Ni.1784  0.357
2009 Fan HY, Liu Z, Shimada M, Sterneck E, Johnson PF, Hedrick SM, Richards JS. MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility. Science (New York, N.Y.). 324: 938-41. PMID 19443782 DOI: 10.1126/Science.1171396  0.37
2009 Dejean AS, Beisner DR, Ch'en IL, Kerdiles YM, Babour A, Arden KC, Castrillon DH, DePinho RA, Hedrick SM. Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Nature Immunology. 10: 504-13. PMID 19363483 DOI: 10.1038/Ni.1729  0.834
2009 Kerdiles YM, Beisner DR, Tinoco R, Dejean AS, Castrillon DH, DePinho RA, Hedrick SM. Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nature Immunology. 10: 176-84. PMID 19136962 DOI: 10.1038/Ni.1689  0.817
2008 D'Souza WN, Chang CF, Fischer AM, Li M, Hedrick SM. The Erk2 MAPK regulates CD8 T cell proliferation and survival. Journal of Immunology (Baltimore, Md. : 1950). 181: 7617-29. PMID 19017950 DOI: 10.4049/Jimmunol.181.11.7617  0.834
2008 McGargill MA, Choy C, Wen BG, Hedrick SM. Drak2 regulates the survival of activated T cells and is required for organ-specific autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 181: 7593-605. PMID 19017948 DOI: 10.4049/Jimmunol.181.11.7593  0.82
2008 Ch'en IL, Beisner DR, Degterev A, Lynch C, Yuan J, Hoffmann A, Hedrick SM. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proceedings of the National Academy of Sciences of the United States of America. 105: 17463-8. PMID 18981423 DOI: 10.1073/Pnas.0808043105  0.833
2008 Wang S, Welte T, McGargill M, Town T, Thompson J, Anderson JF, Flavell RA, Fikrig E, Hedrick SM, Wang T. Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 181: 2084-91. PMID 18641347 DOI: 10.4049/Jimmunol.181.3.2084  0.464
2008 Ch'en IL, Hedrick SM, Hoffmann A. NF-kappaB as a determinant of distinct cell death pathways. Methods in Enzymology. 446: 175-87. PMID 18603122 DOI: 10.1016/S0076-6879(08)01610-8  0.437
2008 Degterev A, Hitomi J, Germscheid M, Ch'en IL, Korkina O, Teng X, Abbott D, Cuny GD, Yuan C, Wagner G, Hedrick SM, Gerber SA, Lugovskoy A, Yuan J. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nature Chemical Biology. 4: 313-21. PMID 18408713 DOI: 10.1038/Nchembio.83  0.356
2008 Hedrick SM. Thymus lineage commitment: a single switch. Immunity. 28: 297-9. PMID 18342002 DOI: 10.1016/J.Immuni.2008.02.011  0.315
2008 Ch'en IL, Beisner DR, Degterev A, Lynch C, Yuan J, Hoffmann A, Hedrick SM. Caspase‐8 regulates a form of death that is distinct from apoptosis in T cells The Faseb Journal. 22: 369-369. DOI: 10.1096/Fasebj.22.2_Supplement.369  0.817
2007 Peter ME, Budd RC, Desbarats J, Hedrick SM, Hueber AO, Newell MK, Owen LB, Pope RM, Tschopp J, Wajant H, Wallach D, Wiltrout RH, Zörnig M, Lynch DH. The CD95 receptor: apoptosis revisited. Cell. 129: 447-50. PMID 17482535 DOI: 10.1016/J.Cell.2007.04.031  0.387
2006 Broussard C, Fleischacker C, Fleischecker C, Horai R, Chetana M, Venegas AM, Sharp LL, Hedrick SM, Fowlkes BJ, Schwartzberg PL. Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. Immunity. 25: 93-104. PMID 16860760 DOI: 10.1016/J.Immuni.2006.05.011  0.553
2006 D'Souza WN, Hedrick SM. Cutting edge: latecomer CD8 T cells are imprinted with a unique differentiation program. Journal of Immunology (Baltimore, Md. : 1950). 177: 777-81. PMID 16818730 DOI: 10.4049/Jimmunol.177.2.777  0.577
2006 Hedrick SM. The TCR of mice and men. Journal of Immunology (Baltimore, Md. : 1950). 176: 2681-2. PMID 16493021 DOI: 10.4049/Jimmunol.176.5.2681  0.355
2005 Fischer AM, Katayama CD, Pagès G, Pouysségur J, Hedrick SM. The role of erk1 and erk2 in multiple stages of T cell development. Immunity. 23: 431-43. PMID 16226508 DOI: 10.1016/J.Immuni.2005.08.013  0.717
2005 Friedrich ML, Wen BG, Bain G, Kee BL, Katayama C, Murre C, Hedrick SM, Walsh CM. DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. International Immunology. 17: 1379-90. PMID 16172133 DOI: 10.1093/Intimm/Dxh315  0.778
2005 Beisner DR, Ch'en IL, Kolla RV, Hoffmann A, Hedrick SM. Cutting edge: innate immunity conferred by B cells is regulated by caspase-8. Journal of Immunology (Baltimore, Md. : 1950). 175: 3469-73. PMID 16148088 DOI: 10.4049/Jimmunol.175.6.3469  0.817
2005 Goldrath AW, Hedrick SM. Central tolerance matters. Immunity. 23: 113-4. PMID 16111630 DOI: 10.1016/J.Immuni.2005.08.004  0.363
2005 McGargill MA, Sharp LL, Bui JD, Hedrick SM, Calbo S. Active Ca2+/calmodulin-dependent protein kinase II gamma B impairs positive selection of T cells by modulating TCR signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 656-64. PMID 16002660 DOI: 10.4049/Jimmunol.175.2.656  0.401
2005 Catlett IM, Hedrick SM. Suppressor of cytokine signaling 1 is required for the differentiation of CD4+ T cells. Nature Immunology. 6: 715-21. PMID 15924143 DOI: 10.1038/Ni1211  0.587
2005 Lin MY, Zal T, Ch'en IL, Gascoigne NR, Hedrick SM. A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase II in T cells: from activation to unresponsiveness. Journal of Immunology (Baltimore, Md. : 1950). 174: 5583-92. PMID 15843557 DOI: 10.4049/Jimmunol.174.9.5583  0.541
2005 Sato K, Imai Y, Higashi N, Kumamoto Y, Onami TM, Hedrick SM, Irimura T. Lack of antigen-specific tissue remodeling in mice deficient in the macrophage galactose-type calcium-type lectin 1/CD301a. Blood. 106: 207-15. PMID 15784728 DOI: 10.1182/Blood-2004-12-4943  0.363
2005 Matis L, Hedrick S, Bluestone J. To T or not to T: is it selection? Current Biology : Cb. 1: 262-4. PMID 15336139 DOI: 10.1016/0960-9822(91)90078-B  0.448
2004 McGargill MA, Wen BG, Walsh CM, Hedrick SM. A deficiency in Drak2 results in a T cell hypersensitivity and an unexpected resistance to autoimmunity. Immunity. 21: 781-91. PMID 15589167 DOI: 10.1016/J.Immuni.2004.10.008  0.838
2004 Soloff RS, Katayama C, Lin MY, Feramisco JR, Hedrick SM. Targeted deletion of protein kinase C lambda reveals a distribution of functions between the two atypical protein kinase C isoforms. Journal of Immunology (Baltimore, Md. : 1950). 173: 3250-60. PMID 15322187 DOI: 10.4049/Jimmunol.173.5.3250  0.472
2003 Beisner DR, Chu IH, Arechiga AF, Hedrick SM, Walsh CM. The requirements for Fas-associated death domain signaling in mature T cell activation and survival. Journal of Immunology (Baltimore, Md. : 1950). 171: 247-56. PMID 12817005 DOI: 10.4049/Jimmunol.171.1.247  0.848
2003 Brinkman-Van der Linden EC, Angata T, Reynolds SA, Powell LD, Hedrick SM, Varki A. CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in mice. Molecular and Cellular Biology. 23: 4199-206. PMID 12773563 DOI: 10.1128/Mcb.23.12.4199-4206.2003  0.373
2002 Mertsching E, Wurster AL, Katayama C, Esko J, Ramsdell F, Marth JD, Hedrick SM. A mouse strain defective for alphabeta versus gammadelta T cell lineage commitment. International Immunology. 14: 1039-53. PMID 12202401 DOI: 10.1093/Intimm/Dxf067  0.515
2002 Onami TM, Lin MY, Page DM, Reynolds SA, Katayama CD, Marth JD, Irimura T, Varki A, Varki N, Hedrick SM. Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins. Molecular and Cellular Biology. 22: 5173-81. PMID 12077344 DOI: 10.1128/Mcb.22.14.5173-5181.2002  0.435
2002 Hedrick SM. T cell development: bottoms-up. Immunity. 16: 619-22. PMID 12049714 DOI: 10.1016/S1074-7613(02)00316-3  0.413
2002 Tsuiji M, Fujimori M, Ohashi Y, Higashi N, Onami TM, Hedrick SM, Irimura T. Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1. The Journal of Biological Chemistry. 277: 28892-901. PMID 12016228 DOI: 10.1074/Jbc.M203774200  0.349
2001 Bain G, Cravatt CB, Loomans C, Alberola-Ila J, Hedrick SM, Murre C. Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade. Nature Immunology. 2: 165-71. PMID 11175815 DOI: 10.1038/84273  0.393
2000 Hayden-Martinez K, Kane LP, Hedrick SM. Effects of a constitutively active form of calcineurin on T cell activation and thymic selection. Journal of Immunology (Baltimore, Md. : 1950). 165: 3713-21. PMID 11034376 DOI: 10.4049/Jimmunol.165.7.3713  0.584
2000 Jepsen K, Hermanson O, Onami TM, Gleiberman AS, Lunyak V, McEvilly RJ, Kurokawa R, Kumar V, Liu F, Seto E, Hedrick SM, Mandel G, Glass CK, Rose DW, Rosenfeld MG. Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell. 102: 753-63. PMID 11030619 DOI: 10.1016/S0092-8674(00)00064-7  0.339
2000 Bui JD, Calbo S, Hayden-Martinez K, Kane LP, Gardner P, Hedrick SM. A role for CaMKII in T cell memory. Cell. 100: 457-67. PMID 10693762 DOI: 10.1016/S0092-8674(00)80681-9  0.524
1999 Bain G, Quong MW, Soloff RS, Hedrick SM, Murre C. Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47. The Journal of Experimental Medicine. 190: 1605-16. PMID 10587351 DOI: 10.1084/Jem.190.11.1605  0.52
1999 Hedrick SM, Sharp LL. T-cell fate. Immunological Reviews. 165: 95-110. PMID 9850855 DOI: 10.1111/J.1600-065X.1998.Tb01233.X  0.523
1998 Schwarz DA, Katayama CD, Hedrick SM. Schlafen, a new family of growth regulatory genes that affect thymocyte development. Immunity. 9: 657-68. PMID 9846487 DOI: 10.1016/S1074-7613(00)80663-9  0.449
1998 Walsh CM, Wen BG, Chinnaiyan AM, O'Rourke K, Dixit VM, Hedrick SM. A role for FADD in T cell activation and development Immunity. 8: 439-449. PMID 9586634 DOI: 10.1016/S1074-7613(00)80549-X  0.82
1998 Weintraub BC, Eckmann L, Okamoto S, Hense M, Hedrick SM, Fierer J. Role of αβ and γδ T Cells in the Host Response toSalmonella Infection as Demonstrated in T-Cell-Receptor-Deficient Mice of Defined Ity Genotypes Infection and Immunity. 66: 882-882. DOI: 10.1128/Iai.66.2.882-882.1998  0.554
1997 Sharp LL, Schwarz DA, Bott CM, Marshall CJ, Hedrick SM. The influence of the MAPK pathway on T cell lineage commitment. Immunity. 7: 609-18. PMID 9390685 DOI: 10.1016/S1074-7613(00)80382-9  0.56
1997 Weintraub BC, Eckmann L, Okamoto S, Hense M, Hedrick SM, Fierer J. Role of alphabeta and gammadelta T cells in the host response to Salmonella infection as demonstrated in T-cell-receptor-deficient mice of defined Ity genotypes. Infection and Immunity. 65: 2306-12. PMID 9169768 DOI: 10.1128/Iai.65.6.2306-2312.1997  0.551
1996 Page DM, Kane LP, Onami TM, Hedrick SM. Cellular and biochemical requirements for thymocyte negative selection. Seminars in Immunology. 8: 69-82. PMID 8920242 DOI: 10.1006/Smim.1996.0010  0.478
1996 Oehen S, Feng L, Xia Y, Surh CD, Hedrick SM. Antigen compartmentation and T helper cell tolerance induction. The Journal of Experimental Medicine. 183: 2617-26. PMID 8676082 DOI: 10.1084/Jem.183.6.2617  0.438
1996 Matechak EO, Killeen N, Hedrick SM, Fowlkes BJ. MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent Immunity. 4: 337-347. PMID 8612128 DOI: 10.1016/S1074-7613(00)80247-2  0.415
1995 Alexander J, Ruppert J, Page DM, Hedrick SM, Franco A, Ishioka GY, Grey HM, Sette A. Antigen analogs as therapeutic agents. Advances in Experimental Medicine and Biology. 386: 109-18. PMID 8851019 DOI: 10.1007/978-1-4613-0331-2_9  0.379
1995 Weintraub BC, Hedrick SM. The enigmatic specificity of gamma delta T cells. Immunologic Research. 14: 163-75. PMID 8778207 DOI: 10.1007/Bf02918214  0.525
1995 Linette GP, Grusby MJ, Hedrick SM, Hansen TH, Glimcher LH, Korsmeyer SJ. Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity. 1: 197-205. PMID 7889408 DOI: 10.1016/1074-7613(94)90098-1  0.57
1995 Duncan DD, Stupakoff A, Hedrick SM, Marcu KB, Siu G. A Myc-associated zinc finger protein binding site is one of four important functional regions in the CD4 promoter Molecular and Cellular Biology. 15: 3179-3186. PMID 7760814 DOI: 10.1128/Mcb.15.6.3179  0.317
1995 Foy TM, Page DM, Waldschmidt TJ, Schoneveld A, Laman JD, Masters SR, Tygrett L, Ledbetter JA, Aruffo A, Claassen E, Xu JC, Flavell RA, Oehen S, Hedrick SM, Noelle RJ. An essential role for gp39, the ligand for CD40, in thymic selection. The Journal of Experimental Medicine. 182: 1377-88. PMID 7595208 DOI: 10.1084/Jem.182.5.1377  0.475
1995 Ruppert J, Franco A, Alexander J, Snoke K, Ishioka GY, Page DM, Hedrick SM, Adorini L, Grey HM, Sette A. MHC Blocking Peptides and T-Cell Receptor Antagonists: Novel Paths to Selective Immunosuppression? Chemical Immunology. 60: 61-78. DOI: 10.1159/000319264  0.419
1995 Katayama C, Eidelman F, Duncan A, Hooshmand F, Hedrick S. Predicted complementarity determining regions of the T cell antigen receptor determine antigen specificity. The Embo Journal. 14: 927-938. DOI: 10.1002/J.1460-2075.1995.Tb07074.X  0.452
1994 Siu G, Wurster AL, Duncan DD, Soliman TM, Hedrick SM. A transcriptional silencer controls the developmental expression of the CD4 gene. The Embo Journal. 13: 3570-9. PMID 8062832 DOI: 10.1002/J.1460-2075.1994.Tb06664.X  0.474
1994 Wurster AL, Siu G, Leiden JM, Hedrick SM. Elf-1 binds to a critical element in a second CD4 enhancer. Molecular and Cellular Biology. 14: 6452-63. PMID 7935370 DOI: 10.1128/Mcb.14.10.6452  0.564
1994 Page DM, Alexander J, Snoke K, Appella E, Sette A, Hedrick SM, Grey HM. Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists. Proceedings of the National Academy of Sciences of the United States of America. 91: 4057-61. PMID 7909610 DOI: 10.1073/Pnas.91.9.4057  0.538
1994 Vasquez NJ, Kane LP, Hedrick SM. Intracellular signals that mediate thymic negative selection. Immunity. 1: 45-56. PMID 7889398 DOI: 10.1016/1074-7613(94)90008-6  0.603
1993 Penninger J, Kishihara K, Molina T, Wallace VA, Timms E, Hedrick SM, Mak TW. Requirement for tyrosine kinase p56lck for thymic development of transgenic gamma delta T cells. Science (New York, N.Y.). 260: 358-61. PMID 8469988 DOI: 10.1126/Science.8469988  0.51
1993 Wells FB, Tatsumi Y, Bluestone JA, Hedrick SM, Allison JP, Matis LA. Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage. The Journal of Experimental Medicine. 177: 1061-70. PMID 8459203 DOI: 10.1084/Jem.177.4.1061  0.444
1993 Dent AL, Matis LA, Bluestone JA, Hedrick SM. Evidence for programmed cell death of self-reactive γδ T cell receptor-positive thymocytes European Journal of Immunology. 23: 2482-2487. PMID 8405049 DOI: 10.1002/Eji.1830231016  0.5
1993 Hedrick SM. Chimeric T cell receptor-immunoglobulin molecules: function and applications. International Reviews of Immunology. 10: 279-90. PMID 8360589 DOI: 10.3109/08830189309061702  0.497
1992 Barrett TA, Delvy ML, Kennedy DM, Lefrancois L, Matis LA, Dent AL, Hedrick SM, Bluestone JA. Mechanism of self-tolerance of gamma/delta T cells in epithelial tissue. The Journal of Experimental Medicine. 175: 65-70. PMID 1730927 DOI: 10.1084/Jem.175.1.65  0.5
1992 Siu G, Wurster AL, Lipsick JS, Hedrick SM. Expression of the CD4 gene requires a Myb transcription factor Molecular and Cellular Biology. 12: 1592-1604. PMID 1347906 DOI: 10.1128/Mcb.12.4.1592  0.469
1992 Vasquez NJ, Kaye J, Hedrick SM. In vivo and in vitro clonal deletion of double-positive thymocytes. The Journal of Experimental Medicine. 175: 1307-16. PMID 1314886 DOI: 10.1084/Jem.175.5.1307  0.529
1991 Barrett TA, Hedrick SM, Dent AL, Delvy ML, Kennedy DM, Matis LA, Bluestone JA. Control of self-reactivity in the intestine. Immunologic Research. 10: 341-8. PMID 1835488 DOI: 10.1007/Bf02919719  0.358
1991 Wells FB, Gahm SJ, Hedrick SM, Bluestone JA, Dent A, Matis LA. Requirement for positive selection of gamma delta receptor-bearing T cells. Science (New York, N.Y.). 253: 903-5. PMID 1831565 DOI: 10.1126/Science.1831565  0.481
1991 Varki A, Hooshmand F, Diaz S, Varki NM, Hedrick SM. Developmental abnormalities in transgenic mice expressing a sialic acid-specific 9-O-acetylesterase. Cell. 65: 65-74. PMID 1826463 DOI: 10.1016/0092-8674(91)90408-Q  0.3
1991 Swain SL, Bradley LM, Croft M, Tonkonogy S, Atkins G, Weinberg AD, Duncan DD, Hedrick SM, Dutton RW, Huston G. Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunological Reviews. 123: 115-44. PMID 1684776 DOI: 10.1111/J.1600-065X.1991.Tb00608.X  0.47
1991 Bluestone JA, Cron RQ, Barrett TA, Houlden B, Sperling AI, Dent A, Hedrick S, Rellahan B, Matis LA. Repertoire development and ligand specificity of murine TCR gamma delta cells. Immunological Reviews. 120: 5-33. PMID 1650760 DOI: 10.1111/J.1600-065X.1991.Tb00585.X  0.419
1991 Dent A, Hedrick SM. Mechanisms of Development of αβ T Cell Antigen Receptor-Bearing Cells in γδ T Cell Antigen Receptor Transgenic Mice Current Topics in Microbiology and Immunology. 173: 121-131. DOI: 10.1007/978-3-642-76492-9_17  0.587
1990 Sorger SB, Hedrick SM. Highly conserved T-cell receptor junctional regions. Evidence for selection at the protein and the DNA level. Immunogenetics. 31: 118-22. PMID 2303278 DOI: 10.1007/Bf00661222  0.447
1990 Fink PJ, Blair MJ, Matis LA, Hedrick SM. Molecular analysis of the influences of positive selection, tolerance induction, and antigen presentation on the T cell receptor repertoire. The Journal of Experimental Medicine. 172: 139-50. PMID 2162903 DOI: 10.1084/Jem.172.1.139  0.554
1990 Hedrick SM, Dent A. A model for γδ T-cell development: Rearranged γ- and δ-chain genes incorporated into the germline of mice Research in Immunology. 141: 588-592. PMID 2095602 DOI: 10.1016/0923-2494(90)90061-3  0.494
1990 Dent AL, Matis LA, Hooshmand F, Widacki SM, Bluestone JA, Hedrick SM. Self-reactive gamma delta T cells are eliminated in the thymus. Nature. 343: 714-9. PMID 1968227 DOI: 10.1038/343714A0  0.573
1989 Kaye J, Hedrick SM. Analysis of specificity for antigen, Mls, and allogenic MHC by transfer of T-cell receptor alpha- and beta-chain genes. Nature. 336: 580-3. PMID 2849059 DOI: 10.1038/336580A0  0.449
1989 Kaye J, Hsu ML, Sauron ME, Jameson SC, Gascoigne NR, Hedrick SM. Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature. 341: 746-9. PMID 2571940 DOI: 10.1038/341746A0  0.555
1989 Becker ML, Near R, Mudgett-Hunter M, Margolies MN, Kubo RT, Kaye J, Hedrick SM. Expression of a hybrid immunoglobulin-T cell receptor protein in transgenic mice. Cell. 58: 911-21. PMID 2528411 DOI: 10.1016/0092-8674(89)90943-4  0.536
1988 Sorger SB, Matis LA, Engel I, McElligott DL, Fink PJ, Hedrick SM. The influence of MHC gene products on the generation of an antigen-specific T-cell repertoire. Annals of the New York Academy of Sciences. 532: 18-32. PMID 2845844 DOI: 10.1111/J.1749-6632.1988.Tb36322.X  0.505
1988 Hedrick SM, Engel I, McElligott DL, Fink PJ, Hsu ML, Hansburg D, Matis LA. Selection of amino acid sequences in the beta chain of the T cell antigen receptor. Science (New York, N.Y.). 239: 1541-4. PMID 2832942 DOI: 10.1126/Science.2832942  0.501
1988 Hedrick SM. Specificity of the T cell receptor for antigen. Advances in Immunology. 43: 193-234. PMID 2461055 DOI: 10.1016/S0065-2776(08)60366-1  0.475
1988 Engel I, Hedrick SM. Site-directed mutations in the VDJ junctional region of a T cell receptor beta chain cause changes in antigenic peptide recognition. Cell. 54: 473-84. PMID 2456856 DOI: 10.1016/0092-8674(88)90068-2  0.421
1988 SORGER SB, MATIS LA, ENGEL I, McELLIGOTT DL, FINK PJ, HEDRICK SM. The Influence of MHC Gene Products on the Generation of an Antigen-Specific T-Cell Repertoirea Annals of the New York Academy of Sciences. 532: 16-17. DOI: 10.1111/j.1749-6632.1988.tb36321.x  0.393
1987 Hedrick SM, Engel I, Fink PJ. Correspondence between functionally significant sequences in immunoglobulin and the T cell receptor for antigen. Advances in Experimental Medicine and Biology. 213: 19-27. PMID 3498298 DOI: 10.1007/978-1-4684-5323-2_3  0.513
1987 Sorger SB, Hedrick SM, Fink PJ, Bookman MA, Matis LA. Generation of diversity in T cell receptor repertoire specific for pigeon cytochrome c. The Journal of Experimental Medicine. 165: 279-301. PMID 3029266 DOI: 10.1084/Jem.165.2.279  0.423
1987 Matis LA, Sorger SB, McElligott DL, Fink PJ, Hedrick SM. The molecular basis of alloreactivity in antigen-specific, major histocompatibility complex-restricted T cell clones. Cell. 51: 59-69. PMID 2443252 DOI: 10.1016/0092-8674(87)90010-9  0.324
1986 Fink PJ, Matis LA, McElligott DL, Bookman M, Hedrick SM. Correlations between T-cell specificity and the structure of the antigen receptor. Nature. 321: 219-226. PMID 3012351 DOI: 10.1038/321219A0  0.484
1985 Reynolds CW, Bonyhadi M, Herberman RB, Young HA, Hedrick SM. Lack of gene rearrangement and mRNA expression of the beta chain of the T cell receptor in spontaneous rat large granular lymphocyte leukemia lines. The Journal of Experimental Medicine. 161: 1249-54. PMID 3872923 DOI: 10.1084/Jem.161.5.1249  0.481
1985 Cohen DI, Hedrick SM, Nielsen EA, D'Eustachio P, Ruddle F, Steinberg AD, Paul WE, Davis MM. Isolation of a cDNA clone corresponding to an X-linked gene family (XLR) closely linked to the murine immunodeficiency disorder xid. Nature. 314: 369-72. PMID 2984575 DOI: 10.1038/314369A0  0.505
1985 Epstein R, Roehm N, Marrack P, Kappler J, Davis M, Hedrick S, Cohn M. Genetic markers of the antigen-specific T cell receptor locus. The Journal of Experimental Medicine. 161: 1219-24. PMID 2580936 DOI: 10.1084/Jem.161.5.1219  0.526
1985 Hedrick SM, Germain RN, Bevan MJ, Dorf M, Engel I, Fink P, Gascoigne N, Heber-Katz E, Kapp J, Kaufmann Y. Rearrangement and transcription of a T-cell receptor beta-chain gene in different T-cell subsets. Proceedings of the National Academy of Sciences of the United States of America. 82: 531-5. PMID 2578667 DOI: 10.1073/Pnas.82.2.531  0.534
1984 Hedrick SM, Nielsen EA, Kavaler J, Cohen DI, Davis MM. Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins. Nature. 308: 153-8. PMID 6546606 DOI: 10.1038/308153A0  0.45
1984 Lee NE, D'Eustachio P, Pravtcheva D, Ruddle FH, Hedrick SM, Davis MM. Murine T cell receptor beta chain is encoded on chromosome 6. The Journal of Experimental Medicine. 160: 905-13. PMID 6206194 DOI: 10.1084/Jem.160.3.905  0.415
1984 Hedrick SM, Cohen DI, Nielsen EA, Davis MM. Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature. 308: 149-153. PMID 6199676 DOI: 10.1038/308149A0  0.516
1984 Davis MM, Chien YH, Gascoigne NR, Hedrick SM. A murine T cell receptor gene complex: isolation, structure and rearrangement Immunological Reviews. 81: 235-258. PMID 6096259 DOI: 10.1111/J.1600-065X.1984.Tb01113.X  0.439
1982 Glimcher LH, Hamano T, Asofsky R, Herber-Katz E, Hedrick S, Schwartz RH, Paul WE. I region-restricted antigen presentation by B cell-B lymphoma hybridomas. Nature. 298: 283-4. PMID 6211627 DOI: 10.1038/298283A0  0.711
1982 Hedrick SM, Matis LA, Hecht TT, Samelson LE, Longo DL, Heber-Katz E, Schwartz RH. The fine specificity of antigen and Ia determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c. Cell. 30: 141-52. PMID 6181895 DOI: 10.1016/0092-8674(82)90020-4  0.521
1982 Matis L, Jones P, Murphy D, Hedrick S, Lerner E, Janeway C, McNicholas J, Schwartz R. Immune response gene function correlates with the expression of an Ia antigen. II. A quantitative deficiency in A(e):E(a), complex expression causes a corresponding defect in antigen-presenting cell function Journal of Experimental Medicine. 155: 508-523. PMID 6173457 DOI: 10.1084/Jem.155.2.508  0.718
1981 Watson J, Hedrick SM. Characterization of T cell growth factors for the clonal analysis of recognition properties of T cells. Molecular Immunology. 17: 1001-10. PMID 6163963 DOI: 10.1016/0161-5890(80)90047-4  0.718
1980 Hedrick SM, Watson JD. Genetic control of the immune response to collagen. I. Quantitative determination of response levels by multiple I-region genes Journal of Immunogenetics. 7: 271-283. PMID 6774029 DOI: 10.1111/J.1744-313X.1980.Tb00936.X  0.517
1979 Hedrick SM, Watson J. Genetic control of the immune response to collagen. II. Antibody responses produced in fetal liver restored radiation chimeras and thymus reconstituted F1 hybrid nude mice. The Journal of Experimental Medicine. 150: 646-52. PMID 113479 DOI: 10.1084/Jem.150.3.646  0.548
1977 Mochizuki D, Hedrick S, Watson J, Kingsbury DT. THE INTERACTION OF HERPES SIMPLEX VIRUS WITH MURINE LYMPHOCYTES I. Mitogenic Properties of Herpes Simplex Virus Journal of Experimental Medicine. 146: 1500-1510. PMID 200698 DOI: 10.1084/Jem.146.6.1500  0.575
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