Eric R. Prossnitz - Publications

Affiliations: 
University of New Mexico, Albuquerque, NM, United States 
Area:
GPER/GPR30, estrogen, cancer, metabolism, cardiovascular system
Website:
https://vivo.health.unm.edu/display/n5071

205 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, ... ... Prossnitz ER, et al. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology. S23-S144. PMID 38123151 DOI: 10.1111/bph.16177  0.334
2023 Prossnitz ER, Barton M. The G protein-coupled oestrogen receptor GPER in health and disease: an update. Nature Reviews. Endocrinology. 1-18. PMID 37193881 DOI: 10.1038/s41574-023-00822-7  0.392
2023 Arterburn JB, Prossnitz ER. G Protein-Coupled Estrogen Receptor GPER: Molecular Pharmacology and Therapeutic Applications. Annual Review of Pharmacology and Toxicology. 63: 295-320. PMID 36662583 DOI: 10.1146/annurev-pharmtox-031122-121944  0.42
2022 Pepermans RA, Prossnitz ER. Assessing Estrogenic Activity of Classical Estrogen Receptor-Binding Compounds. Methods in Molecular Biology (Clifton, N.J.). 2418: 187-201. PMID 35119667 DOI: 10.1007/978-1-0716-1920-9_12  0.348
2021 Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, ... ... Prossnitz ER, et al. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. British Journal of Pharmacology. 178: S27-S156. PMID 34529832 DOI: 10.1111/bph.15538  0.329
2021 Pepermans RA, Sharma G, Prossnitz ER. G Protein-Coupled Estrogen Receptor in Cancer and Stromal Cells: Functions and Novel Therapeutic Perspectives. Cells. 10. PMID 33802978 DOI: 10.3390/cells10030672  0.324
2020 Fredette NC, Malik E, Mukhtar ML, Prossnitz ER, Terada N. A hypertension patient derived induced pluripotent stem cell model demonstrates a role for GPER in hypertension risk and development. American Journal of Physiology. Cell Physiology. PMID 32783656 DOI: 10.1152/Ajpcell.00350.2019  0.313
2020 Sharma G, Hu C, Staquicini DI, Brigman JL, Liu M, Mauvais-Jarvis F, Pasqualini R, Arap W, Arterburn JB, Hathaway HJ, Prossnitz ER. Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes. Science Translational Medicine. 12. PMID 31996464 DOI: 10.1126/Scitranslmed.Aau5956  0.335
2019 Revankar CM, Bologa CG, Pepermans RA, Sharma G, Petrie WK, Alcon SN, Field AS, Ramesh C, Parker MA, Savchuk NP, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER. A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling. Cell Chemical Biology. PMID 31706983 DOI: 10.1016/J.Chembiol.2019.10.009  0.824
2019 Pepermans RA, Prossnitz ER. ERα-targeted endocrine therapy, resistance and the role of GPER. Steroids. 108493. PMID 31518595 DOI: 10.1016/J.Steroids.2019.108493  0.437
2019 Jacenik D, Beswick EJ, Krajewska WM, Prossnitz ER. G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis. World Journal of Gastroenterology. 25: 4092-4104. PMID 31435166 DOI: 10.3748/Wjg.V25.I30.4092  0.459
2019 Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, et al. Autophagy, Inflammation, and Metabolism (AIM) Center in its second year. Autophagy. PMID 31234750 DOI: 10.1080/15548627.2019.1634444  0.59
2019 Triplett KD, Pokhrel S, Castleman MJ, Daly SM, Elmore BO, Joyner JA, Sharma G, Herbert G, Campen MJ, Hathaway HJ, Prossnitz ER, Hall PR. GPER activation protects against epithelial barrier disruption by Staphylococcus aureus α-toxin. Scientific Reports. 9: 1343. PMID 30718654 DOI: 10.1038/S41598-018-37951-3  0.404
2019 Filardo E, Neubig R, Prossnitz ER. G protein-coupled estrogen receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f22/2019.4  0.46
2018 Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Sklar LA, Allers L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, et al. Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations. Autophagy. PMID 29938597 DOI: 10.1080/15548627.2018.1465784  0.585
2018 Marcus JZ, Klobocista M, Karabakhtsian RG, Prossnitz E, Goldberg GL, Huang GS. Female Sex Hormone Receptor Profiling in Uterine Adenosarcomas. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. PMID 29303935 DOI: 10.1097/Igc.0000000000001183  0.499
2018 Meyer MR, Daniel C, Woods CD, Sharma G, Fredette NC, Amann K, Barton M, Prossnitz ER. Abstract P261: GPER is Required for Age-dependent Albuminuria and Glomerulosclerosis: Evidence for its Role in Podocyte Injury and Mesangial Nox1 Regulation Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P261  0.402
2017 Sharma G, Prossnitz ER. G-Protein-Coupled Estrogen Receptor (GPER) and Sex-Specific Metabolic Homeostasis. Advances in Experimental Medicine and Biology. 1043: 427-453. PMID 29224106 DOI: 10.1007/978-3-319-70178-3_20  0.41
2017 Barton M, Prossnitz ER. Rapid vasodilation to raloxifene: role of oestrogen receptors and off-target effects. British Journal of Pharmacology. PMID 28983907 DOI: 10.1111/Bph.14020  0.438
2017 Hill DA, Barry M, Wiggins C, Nibbe A, Royce M, Prossnitz E, Lomo L. Estrogen receptor quantitative measures and breast cancer survival. Breast Cancer Research and Treatment. PMID 28825224 DOI: 10.1007/S10549-017-4439-6  0.365
2017 Prossnitz ER. New Developments in the Rapid Actions of Steroids and their Receptors. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28789973 DOI: 10.1016/J.Jsbmb.2017.08.001  0.438
2017 Fredette NC, Meyer MR, Prossnitz ER. Role of GPER in the activation of endothelial nitric oxide synthase. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28529128 DOI: 10.1016/J.Jsbmb.2017.05.006  0.429
2017 Barton M, Filardo EJ, Lolait SJ, Thomas P, Maggiolini M, Prossnitz ER. Twenty years of the G protein-coupled estrogen receptor GPER: historical and personal perspectives. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28347854 DOI: 10.1016/J.Jsbmb.2017.03.021  0.543
2017 Prossnitz ER. GPER modulators: opportunity Nox on the heels of a class Akt. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28285016 DOI: 10.1016/J.Jsbmb.2017.03.005  0.521
2017 Sharma G, Mauvais-Jarvis F, Prossnitz ER. Roles of G protein-coupled estrogen receptor GPER in metabolic regulation. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28223150 DOI: 10.1016/J.Jsbmb.2017.02.012  0.454
2016 Meyer MR, Fredette NC, Daniel C, Sharma G, Amann K, Arterburn JB, Barton M, Prossnitz ER. Obligatory role for GPER in cardiovascular aging and disease. Science Signaling. 9: ra105. PMID 27803283 DOI: 10.1126/Scisignal.Aag0240  0.366
2016 Dobroff AS, D'Angelo S, Eckhardt BL, Ferrara F, Staquicini DI, Cardó-Vila M, Staquicini FI, Nunes DN, Kim K, Driessen WH, Hajitou A, Lomo LC, Barry M, Krishnamurthy S, Sahin A, ... ... Prossnitz ER, et al. Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791177 DOI: 10.1073/Pnas.1615288113  0.333
2016 Meyer MR, Fredette NC, Sharma G, Barton M, Prossnitz ER. GPER is required for the age-dependent upregulation of the myocardial endothelin system. Life Sciences. PMID 26880534 DOI: 10.1016/J.Lfs.2016.02.041  0.351
2016 Wagener BM, Marjon NA, Prossnitz ER. Regulation of N-Formyl Peptide Receptor Signaling and Trafficking by Arrestin-Src Kinase Interaction. Plos One. 11: e0147442. PMID 26788723 DOI: 10.1371/Journal.Pone.0147442  0.81
2016 Sharma G, Prossnitz ER. GPER/GPR30 Knockout Mice: Effects of GPER on Metabolism. Methods in Molecular Biology (Clifton, N.J.). 1366: 489-502. PMID 26585159 DOI: 10.1007/978-1-4939-3127-9_38  0.361
2015 Zekas E, Prossnitz ER. Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER. Bmc Cancer. 15: 702. PMID 26470790 DOI: 10.1186/S12885-015-1699-6  0.513
2015 Meyer MR, Fredette NC, Barton M, Prossnitz ER. G protein-coupled estrogen receptor inhibits vascular prostanoid production and activity. The Journal of Endocrinology. PMID 26303299 DOI: 10.1530/Joe-15-0257  0.42
2015 Prossnitz ER, Hathaway HJ. What have we learned about GPER function in physiology and disease from knockout mice? The Journal of Steroid Biochemistry and Molecular Biology. 153: 114-26. PMID 26189910 DOI: 10.1016/J.Jsbmb.2015.06.014  0.404
2015 Prossnitz ER, Arterburn JB. International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators. Pharmacological Reviews. 67: 505-40. PMID 26023144 DOI: 10.1124/Pr.114.009712  0.56
2015 Barton M, Prossnitz ER. Emerging roles of GPER in diabetes and atherosclerosis. Trends in Endocrinology and Metabolism: Tem. 26: 185-92. PMID 25767029 DOI: 10.1016/J.Tem.2015.02.003  0.364
2015 Albanito L, Lappano R, Madeo A, Chimento A, Prossnitz ER, Cappello AR, Dolce V, Abonante S, Pezzi V, Maggiolini M. Effects of atrazine on estrogen receptor α- and G protein-coupled receptor 30-mediated signaling and proliferation in cancer cells and cancer-associated fibroblasts. Environmental Health Perspectives. 123: 493-9. PMID 25616260 DOI: 10.1289/Ehp.1408586  0.544
2015 Zechmeister JR, Huang GS, Karabakhtsian R, Schwartz M, Prossnitz ER, Goldberg GL, Klobocista M. Abstract 5257: Immunohistochemical analysis and comprehensive hormone receptor profiling of uterine adenosarcomas at a single institution Cancer Research. 75: 5257-5257. DOI: 10.1158/1538-7445.Am2015-5257  0.429
2014 Meyer MR, Fredette NC, Howard TA, Hu C, Ramesh C, Daniel C, Amann K, Arterburn JB, Barton M, Prossnitz ER. G protein-coupled estrogen receptor protects from atherosclerosis. Scientific Reports. 4: 7564. PMID 25532911 DOI: 10.1038/Srep07564  0.456
2014 Bielecka E, Scavenius C, Kantyka T, Jusko M, Mizgalska D, Szmigielski B, Potempa B, Enghild JJ, Prossnitz ER, Blom AM, Potempa J. Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes anaphylatoxin C5a activity. The Journal of Biological Chemistry. 289: 32481-7. PMID 25324545 DOI: 10.1074/Jbc.C114.617142  0.311
2014 Nayak TK, Ramesh C, Hathaway HJ, Norenberg JP, Arterburn JB, Prossnitz ER. GPER-targeted, 99mTc-labeled, nonsteroidal ligands demonstrate selective tumor imaging and in vivo estrogen binding. Molecular Cancer Research : McR. 12: 1635-43. PMID 25030373 DOI: 10.1158/1541-7786.Mcr-14-0289  0.496
2014 Marjon NA, Hu C, Hathaway HJ, Prossnitz ER. G protein-coupled estrogen receptor regulates mammary tumorigenesis and metastasis. Molecular Cancer Research : McR. 12: 1644-54. PMID 25030371 DOI: 10.1158/1541-7786.Mcr-14-0128-T  0.784
2014 Vaucher L, Funaro MG, Mehta A, Mielnik A, Bolyakov A, Prossnitz ER, Schlegel PN, Paduch DA. Activation of GPER-1 estradiol receptor downregulates production of testosterone in isolated rat Leydig cells and adult human testis. Plos One. 9: e92425. PMID 24736568 DOI: 10.1371/Journal.Pone.0092425  0.428
2014 Scaling AL, Prossnitz ER, Hathaway HJ. GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast. Hormones & Cancer. 5: 146-60. PMID 24718936 DOI: 10.1007/S12672-014-0174-1  0.398
2014 Meyer MR, Fredette NC, Barton M, Prossnitz ER. Endothelin-1 but not angiotensin II contributes to functional aging in murine carotid arteries. Life Sciences. 118: 213-8. PMID 24607776 DOI: 10.1016/J.Lfs.2014.02.027  0.355
2014 Dai D, Bradford AP, Prossnitz ER. Endometrial cancer: molecular and cellular basis of tumor development, novel biomarkers and therapeutic agents, and innovative research approaches. Obstetrics and Gynecology International. 2014: 710405. PMID 24550988 DOI: 10.1155/2014/710405  0.414
2014 Prossnitz ER, Barton M. Estrogen biology: new insights into GPER function and clinical opportunities. Molecular and Cellular Endocrinology. 389: 71-83. PMID 24530924 DOI: 10.1016/J.Mce.2014.02.002  0.496
2013 Petrie WK, Dennis MK, Hu C, Dai D, Arterburn JB, Smith HO, Hathaway HJ, Prossnitz ER. G protein-coupled estrogen receptor-selective ligands modulate endometrial tumor growth. Obstetrics and Gynecology International. 2013: 472720. PMID 24379833 DOI: 10.1155/2013/472720  0.831
2013 Guo H, Hathaway H, Royce ME, Prossnitz ER, Miao Y. Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. Bioorganic & Medicinal Chemistry Letters. 23: 5484-7. PMID 24018188 DOI: 10.1016/J.Bmcl.2013.08.075  0.434
2013 Barton M, Meyer MR, Prossnitz ER. Alike but not the same: anatomic heterogeneity of estrogen receptor-mediated vasodilation. Journal of Cardiovascular Pharmacology. 62: 22-5. PMID 23615160 DOI: 10.1097/Fjc.0B013E31829709D4  0.369
2013 Brunsing RL, Owens KS, Prossnitz ER. The G protein-coupled estrogen receptor (GPER) agonist G-1 expands the regulatory T-cell population under TH17-polarizing conditions. Journal of Immunotherapy (Hagerstown, Md. : 1997). 36: 190-6. PMID 23502766 DOI: 10.1097/Cji.0B013E31828D8E3B  0.788
2012 Prossnitz ER. G protein-coupled estrogen receptor: a new therapeutic target in stroke and traumatic brain/spinal cord injury? Critical Care Medicine. 40: 3323-5. PMID 23164781 DOI: 10.1097/Ccm.0B013E31826Be998  0.421
2012 Burai R, Ramesh C, Nayak TK, Dennis MK, Bryant BK, Prossnitz ER, Arterburn JB. Synthesis and characterization of tricarbonyl-Re/Tc(I) chelate probes targeting the G protein-coupled estrogen receptor GPER/GPR30. Plos One. 7: e46861. PMID 23077529 DOI: 10.1371/Journal.Pone.0046861  0.523
2012 Meyer MR, Field AS, Kanagy NL, Barton M, Prossnitz ER. GPER regulates endothelin-dependent vascular tone and intracellular calcium. Life Sciences. 91: 623-7. PMID 22326502 DOI: 10.1016/J.Lfs.2012.01.007  0.335
2012 Meyer MR, Amann K, Field AS, Hu C, Hathaway HJ, Kanagy NL, Walker MK, Barton M, Prossnitz ER. Deletion of G protein-coupled estrogen receptor increases endothelial vasoconstriction. Hypertension. 59: 507-12. PMID 22203741 DOI: 10.1161/Hypertensionaha.111.184606  0.466
2011 Meyer MR, Prossnitz ER, Barton M. GPER/GPR30 and Regulation of Vascular Tone and Blood Pressure. Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry. 11: 255-261. PMID 24999376 DOI: 10.2174/1871522211108040255  0.472
2011 Prossnitz ER, Barton M. The G-protein-coupled estrogen receptor GPER in health and disease. Nature Reviews. Endocrinology. 7: 715-26. PMID 21844907 DOI: 10.1038/Nrendo.2011.122  0.462
2011 Yu X, Ma H, Barman SA, Liu AT, Sellers M, Stallone JN, Prossnitz ER, White RE, Han G. Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscle. American Journal of Physiology. Endocrinology and Metabolism. 301: E882-8. PMID 21791623 DOI: 10.1152/Ajpendo.00037.2011  0.356
2011 Dennis MK, Field AS, Burai R, Ramesh C, Petrie WK, Bologa CG, Oprea TI, Yamaguchi Y, Hayashi S, Sklar LA, Hathaway HJ, Arterburn JB, Prossnitz ER. Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity. The Journal of Steroid Biochemistry and Molecular Biology. 127: 358-66. PMID 21782022 DOI: 10.1016/J.Jsbmb.2011.07.002  0.823
2011 Guo H, Lu J, Hathaway H, Royce ME, Prossnitz ER, Miao Y. Synthesis and evaluation of novel gonadotropin-releasing hormone receptor-targeting peptides. Bioconjugate Chemistry. 22: 1682-9. PMID 21749045 DOI: 10.1021/Bc200252J  0.382
2011 Meyer MR, Prossnitz ER, Barton M. The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function. Vascular Pharmacology. 55: 17-25. PMID 21742056 DOI: 10.1016/J.Vph.2011.06.003  0.508
2011 Brunsing RL, Prossnitz ER. Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1. Immunology. 134: 93-106. PMID 21722102 DOI: 10.1111/J.1365-2567.2011.03471.X  0.768
2011 Sharma G, Prossnitz ER. Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells. Endocrinology. 152: 3030-9. PMID 21673097 DOI: 10.1210/En.2011-0091  0.448
2011 Glass JP, Parasher G, Arias-Pulido H, Donohue R, Prossnitz ER, Cerilli LA. Mesothelin and GPR30 staining among a spectrum of pancreatic epithelial neoplasms. International Journal of Surgical Pathology. 19: 588-96. PMID 21632639 DOI: 10.1177/1066896911409575  0.386
2011 Barton M, Meyer MR, Prossnitz ER. Estrogen-independent activation of estrogen receptors. Hypertension. 57: 1056-7. PMID 21536981 DOI: 10.1161/Hypertensionaha.111.173427  0.381
2011 Lindsey SH, Carver KA, Prossnitz ER, Chappell MC. Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat. Journal of Cardiovascular Pharmacology. 57: 598-603. PMID 21326105 DOI: 10.1097/Fjc.0B013E3182135F1C  0.375
2011 Kasai RS, Suzuki KG, Prossnitz ER, Koyama-Honda I, Nakada C, Fujiwara TK, Kusumi A. Full characterization of GPCR monomer-dimer dynamic equilibrium by single molecule imaging. The Journal of Cell Biology. 192: 463-80. PMID 21300851 DOI: 10.1083/Jcb.201009128  0.458
2011 Meyer MR, Clegg DJ, Prossnitz ER, Barton M. Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors. Acta Physiologica (Oxford, England). 203: 259-69. PMID 21281456 DOI: 10.1111/J.1748-1716.2010.02237.X  0.332
2011 Arias-Pulido H, Ahmed R, Chaher N, Vargas J, Joste N, Lomo L, Qualls C, Azziez S, Terki N, Bouzid K, Prossnitz E, Royce M. P4-01-19: SRC-1 Expression Is a Prognostic Factor of Breast Cancer-Specific and Disease-Free Survival in Inflammatory Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-01-19  0.334
2010 Kuo J, Hamid N, Bondar G, Prossnitz ER, Micevych P. Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12950-7. PMID 20881113 DOI: 10.1523/Jneurosci.1158-10.2010  0.397
2010 Meyer MR, Baretella O, Prossnitz ER, Barton M. Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780. Pharmacology. 86: 58-64. PMID 20639684 DOI: 10.1159/000315497  0.363
2010 Huang GS, Gunter MJ, Arend RC, Li M, Arias-Pulido H, Prossnitz ER, Goldberg GL, Smith HO. Co-expression of GPR30 and ERbeta and their association with disease progression in uterine carcinosarcoma. American Journal of Obstetrics and Gynecology. 203: 242.e1-5. PMID 20605134 DOI: 10.1016/J.Ajog.2010.04.046  0.472
2010 Nayak TK, Dennis MK, Ramesh C, Burai R, Atcher RW, Sklar LA, Norenberg JP, Hathaway HJ, Arterburn JB, Prossnitz ER. Influence of charge on cell permeability and tumor imaging of GPR30-targeted 111in-labeled nonsteroidal imaging agents. Acs Chemical Biology. 5: 681-90. PMID 20486699 DOI: 10.1021/Cb1000636  0.696
2010 Burai R, Ramesh C, Shorty M, Curpan R, Bologa C, Sklar LA, Oprea T, Prossnitz ER, Arterburn JB. Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs. Organic & Biomolecular Chemistry. 8: 2252-9. PMID 20401403 DOI: 10.1039/C001307B  0.646
2010 Ariazi EA, Brailoiu E, Yerrum S, Shupp HA, Slifker MJ, Cunliffe HE, Black MA, Donato AL, Arterburn JB, Oprea TI, Prossnitz ER, Dun NJ, Jordan VC. The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells. Cancer Research. 70: 1184-94. PMID 20086172 DOI: 10.1158/0008-5472.Can-09-3068  0.466
2010 Ramesh C, Nayak TK, Burai R, Dennis MK, Hathaway HJ, Sklar LA, Prossnitz ER, Arterburn JB. Synthesis and characterization of iodinated tetrahydroquinolines targeting the G protein-coupled estrogen receptor GPR30. Journal of Medicinal Chemistry. 53: 1004-14. PMID 20041667 DOI: 10.1021/Jm9011802  0.721
2010 Takanami K, Sakamoto H, Matsuda K, Hosokawa K, Nishi M, Prossnitz ER, Kawata M. Expression of G protein-coupled receptor 30 in the spinal somatosensory system. Brain Research. 1310: 17-28. PMID 19912997 DOI: 10.1016/J.Brainres.2009.11.004  0.361
2010 Arias-Pulido H, Royce M, Gong Y, Joste N, Lomo L, Lee SJ, Chaher N, Verschraegen C, Lara J, Prossnitz ER, Cristofanilli M. GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer. Breast Cancer Research and Treatment. 123: 51-8. PMID 19902352 DOI: 10.1007/S10549-009-0631-7  0.386
2009 Guo H, Yang J, Gallazzi F, Prossnitz ER, Sklar LA, Miao Y. Effect of DOTA position on melanoma targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide. Bioconjugate Chemistry. 20: 2162-8. PMID 19817405 DOI: 10.1021/Bc9003475  0.611
2009 Arterburn JB, Oprea TI, Prossnitz ER, Edwards BS, Sklar LA. Discovery of selective probes and antagonists for G-protein-coupled receptors FPR/FPRL1 and GPR30. Current Topics in Medicinal Chemistry. 9: 1227-36. PMID 19807662 DOI: 10.2174/156802609789753608  0.744
2009 Blasko E, Haskell CA, Leung S, Gualtieri G, Halks-Miller M, Mahmoudi M, Dennis MK, Prossnitz ER, Karpus WJ, Horuk R. Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis. Journal of Neuroimmunology. 214: 67-77. PMID 19664827 DOI: 10.1016/J.Jneuroim.2009.06.023  0.479
2009 Wagener BM, Marjon NA, Revankar CM, Prossnitz ER. Adaptor protein-2 interaction with arrestin regulates GPCR recycling and apoptosis. Traffic (Copenhagen, Denmark). 10: 1286-300. PMID 19602204 DOI: 10.1111/J.1600-0854.2009.00957.X  0.832
2009 Arias-Pulido H, Smith HO, Joste NE, Bocklage T, Qualls CR, Chavez A, Prossnitz ER, Verschraegen CF. Estrogen and progesterone receptor status and outcome in epithelial ovarian cancers and low malignant potential tumors. Gynecologic Oncology. 114: 480-5. PMID 19560192 DOI: 10.1016/J.Ygyno.2009.05.045  0.353
2009 Meyer MR, Haas E, Prossnitz ER, Barton M. Non-genomic regulation of vascular cell function and growth by estrogen. Molecular and Cellular Endocrinology. 308: 9-16. PMID 19549587 DOI: 10.1016/J.Mce.2009.03.009  0.438
2009 Smith HO, Arias-Pulido H, Kuo DY, Howard T, Qualls CR, Lee SJ, Verschraegen CF, Hathaway HJ, Joste NE, Prossnitz ER. GPR30 predicts poor survival for ovarian cancer. Gynecologic Oncology. 114: 465-71. PMID 19501895 DOI: 10.1016/J.Ygyno.2009.05.015  0.443
2009 Haynes MK, Strouse JJ, Waller A, Leitao A, Curpan RF, Bologa C, Oprea TI, Prossnitz ER, Edwards BS, Sklar LA, Thompson TA. Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system. Journal of Biomolecular Screening. 14: 596-609. PMID 19470718 DOI: 10.1177/1087057109335671  0.634
2009 Prossnitz ER, Maggiolini M. Mechanisms of estrogen signaling and gene expression via GPR30. Molecular and Cellular Endocrinology. 308: 32-8. PMID 19464786 DOI: 10.1016/J.Mce.2009.03.026  0.49
2009 Prossnitz ER, Barton M. Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER. Prostaglandins & Other Lipid Mediators. 89: 89-97. PMID 19442754 DOI: 10.1016/J.Prostaglandins.2009.05.001  0.559
2009 Dennis MK, Burai R, Ramesh C, Petrie WK, Alcon SN, Nayak TK, Bologa CG, Leitao A, Brailoiu E, Deliu E, Dun NJ, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, ... Prossnitz ER, et al. In vivo effects of a GPR30 antagonist. Nature Chemical Biology. 5: 421-7. PMID 19430488 DOI: 10.1038/Nchembio.168  0.835
2009 Hazell GG, Yao ST, Roper JA, Prossnitz ER, O'Carroll AM, Lolait SJ. Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues. The Journal of Endocrinology. 202: 223-36. PMID 19420011 DOI: 10.1677/Joe-09-0066  0.396
2009 Edwards BS, Young SM, Ivnitsky-Steele I, Ye RD, Prossnitz ER, Sklar LA. High-content screening: flow cytometry analysis. Methods in Molecular Biology (Clifton, N.J.). 486: 151-65. PMID 19347622 DOI: 10.1007/978-1-60327-545-3_11  0.695
2009 Haas E, Bhattacharya I, Brailoiu E, Damjanović M, Brailoiu GC, Gao X, Mueller-Guerre L, Marjon NA, Gut A, Minotti R, Meyer MR, Amann K, Ammann E, Perez-Dominguez A, Genoni M, ... ... Prossnitz ER, et al. Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity. Circulation Research. 104: 288-91. PMID 19179659 DOI: 10.1161/Circresaha.108.190892  0.798
2009 Dun SL, Brailoiu GC, Gao X, Brailoiu E, Arterburn JB, Prossnitz ER, Oprea TI, Dun NJ. Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia. Journal of Neuroscience Research. 87: 1610-9. PMID 19125412 DOI: 10.1002/Jnr.21980  0.329
2009 Xu H, Qin S, Carrasco GA, Dai Y, Filardo EJ, Prossnitz ER, Battaglia G, Doncarlos LL, Muma NA. Extra-nuclear estrogen receptor GPR30 regulates serotonin function in rat hypothalamus. Neuroscience. 158: 1599-607. PMID 19095043 DOI: 10.1016/J.Neuroscience.2008.11.028  0.404
2009 Strouse JJ, Young SM, Mitchell HD, Ye RD, Prossnitz ER, Sklar LA, Edwards BS. A novel fluorescent cross-reactive formylpeptide receptor/formylpeptide receptor-like 1 hexapeptide ligand. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 264-70. PMID 19006074 DOI: 10.1002/Cyto.A.20670  0.695
2009 Young SM, Bologa CM, Fara D, Bryant BK, Strouse JJ, Arterburn JB, Ye RD, Oprea TI, Prossnitz ER, Sklar LA, Edwards BS. Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 253-63. PMID 18785269 DOI: 10.1002/Cyto.A.20645  0.715
2009 Takanami K, Sakamoto H, Matsuda K, Hosokawa K, Nishi M, Prossnitz ER, Kawata M. Expression and its hormonal regulation of G protein-coupled receptor 30 in the rat spinal somatosensory system Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.474  0.43
2008 Albanito L, Lappano R, Madeo A, Chimento A, Prossnitz ER, Cappello AR, Dolce V, Abonante S, Pezzi V, Maggiolini M. G-protein-coupled receptor 30 and estrogen receptor-alpha are involved in the proliferative effects induced by atrazine in ovarian cancer cells. Environmental Health Perspectives. 116: 1648-55. PMID 19079715 DOI: 10.1289/Ehp.11297  0.538
2008 Nayak TK, Atcher RW, Prossnitz ER, Norenberg JP. Enhancement of somatostatin-receptor-targeted (177)Lu-[DOTA(0)-Tyr(3)]-octreotide therapy by gemcitabine pretreatment-mediated receptor uptake, up-regulation and cell cycle modulation. Nuclear Medicine and Biology. 35: 673-8. PMID 18678352 DOI: 10.1016/J.Nucmedbio.2008.05.003  0.426
2008 Matsuda K, Sakamoto H, Mori H, Hosokawa K, Kawamura A, Itose M, Nishi M, Prossnitz ER, Kawata M. Expression and intracellular distribution of the G protein-coupled receptor 30 in rat hippocampal formation. Neuroscience Letters. 441: 94-9. PMID 18586395 DOI: 10.1016/J.Neulet.2008.05.108  0.462
2008 Wang C, Prossnitz ER, Roy SK. G protein-coupled receptor 30 expression is required for estrogen stimulation of primordial follicle formation in the hamster ovary. Endocrinology. 149: 4452-61. PMID 18499747 DOI: 10.1210/En.2008-0441  0.399
2008 Nayak TK, Hathaway HJ, Ramesh C, Arterburn JB, Dai D, Sklar LA, Norenberg JP, Prossnitz ER. Preclinical development of a neutral, estrogen receptor-targeted, tridentate 99mTc(I)-estradiol-pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 978-86. PMID 18483091 DOI: 10.2967/Jnumed.107.048546  0.648
2008 Teng J, Wang ZY, Prossnitz ER, Bjorling DE. The G protein-coupled receptor GPR30 inhibits human urothelial cell proliferation. Endocrinology. 149: 4024-34. PMID 18467434 DOI: 10.1210/En.2007-1669  0.438
2008 Prossnitz ER, Oprea TI, Sklar LA, Arterburn JB. The ins and outs of GPR30: a transmembrane estrogen receptor. The Journal of Steroid Biochemistry and Molecular Biology. 109: 350-3. PMID 18406603 DOI: 10.1016/J.Jsbmb.2008.03.006  0.737
2008 Dennis MK, Bowles HJ, MacKenzie DA, Burchiel SW, Edwards BS, Sklar LA, Prossnitz ER, Thompson TA. A multifunctional androgen receptor screening assay using the high-throughput Hypercyt flow cytometry system. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 390-9. PMID 18340645 DOI: 10.1002/Cyto.A.20552  0.687
2008 Prossnitz ER, Arterburn JB, Smith HO, Oprea TI, Sklar LA, Hathaway HJ. Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. Annual Review of Physiology. 70: 165-90. PMID 18271749 DOI: 10.1146/Annurev.Physiol.70.113006.100518  0.764
2008 Prossnitz ER, Sklar LA, Oprea TI, Arterburn JB. GPR30: a novel therapeutic target in estrogen-related disease. Trends in Pharmacological Sciences. 29: 116-23. PMID 18262661 DOI: 10.1016/J.Tips.2008.01.001  0.744
2008 Kasai RS, Prossnitz ER, Kusumi A. 1P-191 Dimers of formyl peptide receptor, a GPCR, exist under physiological conditions : a study using single-molecule tracking(The 46th Annual Meeting of the Biophysical Society of Japan) Seibutsu Butsuri. 48: S51. DOI: 10.2142/Biophys.48.S51_1  0.38
2007 Edwards BS, Young SM, Saunders MJ, Bologa C, Oprea TI, Ye RD, Prossnitz ER, Graves SW, Sklar LA. High-throughput flow cytometry for drug discovery. Expert Opinion On Drug Discovery. 2: 685-96. PMID 23488958 DOI: 10.1517/17460441.2.5.685  0.628
2007 Wu Y, Buranda T, Simons PC, Lopez GP, McIntire WE, Garrison JC, Prossnitz ER, Sklar LA. Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides. Analytical Biochemistry. 371: 10-20. PMID 17904091 DOI: 10.1016/J.Ab.2007.08.011  0.705
2007 Sakamoto H, Matsuda K, Hosokawa K, Nishi M, Morris JF, Prossnitz ER, Kawata M. Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei. Endocrinology. 148: 5842-50. PMID 17872373 DOI: 10.1210/En.2007-0436  0.441
2007 Buranda T, Waller A, Wu Y, Simons PC, Biggs S, Prossnitz ER, Sklar LA. Some mechanistic insights into GPCR activation from detergent-solubilized ternary complexes on beads. Advances in Protein Chemistry. 74: 95-135. PMID 17854656 DOI: 10.1016/S0065-3233(07)74003-2  0.716
2007 Revankar CM, Mitchell HD, Field AS, Burai R, Corona C, Ramesh C, Sklar LA, Arterburn JB, Prossnitz ER. Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30. Acs Chemical Biology. 2: 536-44. PMID 17655271 DOI: 10.1021/Cb700072N  0.749
2007 Wang C, Prossnitz ER, Roy SK. Expression of G protein-coupled receptor 30 in the hamster ovary: differential regulation by gonadotropins and steroid hormones. Endocrinology. 148: 4853-64. PMID 17640985 DOI: 10.1210/En.2007-0727  0.441
2007 Brailoiu E, Dun SL, Brailoiu GC, Mizuo K, Sklar LA, Oprea TI, Prossnitz ER, Dun NJ. Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. The Journal of Endocrinology. 193: 311-21. PMID 17470522 DOI: 10.1677/Joe-07-0017  0.701
2007 Smith HO, Leslie KK, Singh M, Qualls CR, Revankar CM, Joste NE, Prossnitz ER. GPR30: a novel indicator of poor survival for endometrial carcinoma. American Journal of Obstetrics and Gynecology. 196: 386.e1-9; discussion. PMID 17403429 DOI: 10.1016/J.Ajog.2007.01.004  0.32
2007 Albanito L, Madeo A, Lappano R, Vivacqua A, Rago V, Carpino A, Oprea TI, Prossnitz ER, Musti AM, Andò S, Maggiolini M. G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Research. 67: 1859-66. PMID 17308128 DOI: 10.1158/0008-5472.Can-06-2909  0.475
2007 Nayak TK, Norenberg JP, Anderson TL, Prossnitz ER, Stabin MG, Atcher RW. Somatostatin-receptor-targeted alpha-emitting 213Bi is therapeutically more effective than beta(-)-emitting 177Lu in human pancreatic adenocarcinoma cells. Nuclear Medicine and Biology. 34: 185-93. PMID 17307126 DOI: 10.1016/J.Nucmedbio.2006.11.006  0.337
2007 Xue M, Hsieh G, Raymond-Stintz MA, Pfeiffer J, Roberts D, Steinberg SL, Oliver JM, Prossnitz ER, Lidke DS, Wilson BS. Activated N-formyl peptide receptor and high-affinity IgE receptor occupy common domains for signaling and internalization. Molecular Biology of the Cell. 18: 1410-20. PMID 17267694 DOI: 10.1091/Mbc.E05-11-1073  0.515
2007 Prossnitz ER, Arterburn JB, Sklar LA. GPR30: A G protein-coupled receptor for estrogen. Molecular and Cellular Endocrinology. 265: 138-42. PMID 17222505 DOI: 10.1016/J.Mce.2006.12.010  0.748
2006 Prossnitz ER, Arterburn JB, Edwards BS, Sklar LA, Oprea TI. Steroid-binding G-protein-coupled receptors: new drug discovery targets for old ligands. Expert Opinion On Drug Discovery. 1: 137-50. PMID 23495797 DOI: 10.1517/17460441.1.2.137  0.713
2006 Prossnitz ER, Sklar LA. Modulation of GPCR conformations by ligands, G-proteins, and arrestins. Ernst Schering Foundation Symposium Proceedings. 211-28. PMID 17703584  0.719
2006 Edwards BS, Young SM, Oprea TI, Bologa CG, Prossnitz ER, Sklar LA. Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform. Nature Protocols. 1: 59-66. PMID 17406212 DOI: 10.1038/Nprot.2006.9  0.737
2006 Ramesh C, Bryant B, Nayak T, Revankar CM, Anderson T, Carlson KE, Katzenellenbogen JA, Sklar LA, Norenberg JP, Prossnitz ER, Arterburn JB. Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERalpha/beta with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates. Journal of the American Chemical Society. 128: 14476-7. PMID 17090028 DOI: 10.1021/Ja066360P  0.743
2006 Potter RM, Maestas DC, Cimino DF, Prossnitz ER. Regulation of N-formyl peptide receptor signaling and trafficking by individual carboxyl-terminal serine and threonine residues. Journal of Immunology (Baltimore, Md. : 1950). 176: 5418-25. PMID 16622009 DOI: 10.4049/Jimmunol.176.9.5418  0.814
2006 Tessema M, Simons PC, Cimino DF, Sanchez L, Waller A, Posner RG, Wandinger-Ness A, Prossnitz ER, Sklar LA. Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 326-34. PMID 16604533 DOI: 10.1002/Cyto.A.20259  0.632
2006 Bologa CG, Revankar CM, Young SM, Edwards BS, Arterburn JB, Kiselyov AS, Parker MA, Tkachenko SE, Savchuck NP, Sklar LA, Oprea TI, Prossnitz ER. Virtual and biomolecular screening converge on a selective agonist for GPR30. Nature Chemical Biology. 2: 207-12. PMID 16520733 DOI: 10.1038/Nchembio775  0.757
2006 Okun I, Malarchuk S, Dubrovskaya E, Khvat A, Tkachenko S, Kysil V, Ilyin A, Kravchenko D, Prossnitz ER, Sklar L, Ivachtchenko A. Screening for caspase-3 inhibitors: a new class of potent small-molecule inhibitors of caspase-3. Journal of Biomolecular Screening. 11: 277-85. PMID 16490769 DOI: 10.1177/1087057105285048  0.608
2006 Makino A, Prossnitz ER, Bünemann M, Wang JM, Yao W, Schmid-Schönbein GW. G protein-coupled receptors serve as mechanosensors for fluid shear stress in neutrophils. American Journal of Physiology. Cell Physiology. 290: C1633-9. PMID 16436471 DOI: 10.1152/Ajpcell.00576.2005  0.349
2006 Fara DC, Oprea TI, Prossnitz ER, Bologa CG, Edwards BS, Sklar LA. Integration of virtual and physical screening Drug Discovery Today: Technologies. 3: 377-385. DOI: 10.1016/J.Ddtec.2006.11.003  0.605
2005 Edwards BS, Bologa C, Young SM, Balakin KV, Prossnitz ER, Savchuck NP, Sklar LA, Oprea TI. Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists. Molecular Pharmacology. 68: 1301-10. PMID 16118363 DOI: 10.1124/Mol.105.014068  0.692
2005 Oprea TI, Bologa CG, Edwards BS, Prossnitz ER, Sklar LA. Post-high-throughput screening analysis: an empirical compound prioritization scheme. Journal of Biomolecular Screening. 10: 419-26. PMID 16093551 DOI: 10.1177/1087057104272660  0.636
2005 Carter JM, Gurevich VV, Prossnitz ER, Engen JR. Conformational differences between arrestin2 and pre-activated mutants as revealed by hydrogen exchange mass spectrometry. Journal of Molecular Biology. 351: 865-78. PMID 16045931 DOI: 10.1016/J.Jmb.2005.06.048  0.48
2005 Young SM, Bologa C, Prossnitz ER, Oprea TI, Sklar LA, Edwards BS. High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands. Journal of Biomolecular Screening. 10: 374-82. PMID 15964939 DOI: 10.1177/1087057105274532  0.691
2005 Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science (New York, N.Y.). 307: 1625-30. PMID 15705806 DOI: 10.1126/Science.1106943  0.746
2005 Key TA, Vines CM, Wagener BM, Gurevich VV, Sklar LA, Prossnitz ER. Inhibition of chemoattractant N-formyl peptide receptor trafficking by active arrestins. Traffic (Copenhagen, Denmark). 6: 87-99. PMID 15634210 DOI: 10.1111/J.1600-0854.2004.00248.X  0.83
2004 Waller A, Simons PC, Biggs SM, Edwards BS, Prossnitz ER, Sklar LA. Techniques: GPCR assembly, pharmacology and screening by flow cytometry. Trends in Pharmacological Sciences. 25: 663-9. PMID 15530645 DOI: 10.1016/J.Tips.2004.10.009  0.705
2004 Xue M, Vines CM, Buranda T, Cimino DF, Bennett TA, Prossnitz ER. N-formyl peptide receptors cluster in an active raft-associated state prior to phosphorylation. The Journal of Biological Chemistry. 279: 45175-84. PMID 15302864 DOI: 10.1074/Jbc.M407053200  0.485
2004 Edwards BS, Oprea T, Prossnitz ER, Sklar LA. Flow cytometry for high-throughput, high-content screening. Current Opinion in Chemical Biology. 8: 392-8. PMID 15288249 DOI: 10.1016/J.Cbpa.2004.06.007  0.665
2004 Vines CM, Prossnitz ER. Mechanisms of G protein-coupled receptor-mediated degranulation. Fems Microbiology Letters. 236: 1-6. PMID 15212783 DOI: 10.1111/J.1574-6968.2004.Tb09619.X  0.467
2004 Prossnitz ER. Novel roles for arrestins in the post-endocytic trafficking of G protein-coupled receptors. Life Sciences. 75: 893-9. PMID 15193949 DOI: 10.1016/J.Lfs.2004.04.003  0.566
2004 Chigaev A, Zwartz GJ, Buranda T, Edwards BS, Prossnitz ER, Sklar LA. Conformational regulation of alpha 4 beta 1-integrin affinity by reducing agents. "Inside-out" signaling is independent of and additive to reduction-regulated integrin activation. The Journal of Biological Chemistry. 279: 32435-43. PMID 15166232 DOI: 10.1074/Jbc.M404387200  0.688
2004 Postma B, Poppelier MJ, van Galen JC, Prossnitz ER, van Strijp JA, de Haas CJ, van Kessel KP. Chemotaxis inhibitory protein of Staphylococcus aureus binds specifically to the C5a and formylated peptide receptor. Journal of Immunology (Baltimore, Md. : 1950). 172: 6994-7001. PMID 15153520 DOI: 10.4049/Jimmunol.172.11.6994  0.476
2004 Revankar CM, Vines CM, Cimino DF, Prossnitz ER. Arrestins block G protein-coupled receptor-mediated apoptosis. The Journal of Biological Chemistry. 279: 24578-84. PMID 15051714 DOI: 10.1074/Jbc.M402121200  0.522
2004 Young SM, Curry MS, Ransom JT, Ballesteros JA, Prossnitz ER, Sklar LA, Edwards BS. High-throughput microfluidic mixing and multiparametric cell sorting for bioactive compound screening. Journal of Biomolecular Screening. 9: 103-11. PMID 15006133 DOI: 10.1177/1087057103262335  0.648
2004 Simons PC, Biggs SM, Waller A, Foutz T, Cimino DF, Guo Q, Neubig RR, Tang WJ, Prossnitz ER, Sklar LA. Real-time analysis of ternary complex on particles: direct evidence for partial agonism at the agonist-receptor-G protein complex assembly step of signal transduction. The Journal of Biological Chemistry. 279: 13514-21. PMID 14726530 DOI: 10.1074/Jbc.M310306200  0.737
2003 Chigaev A, Buranda T, Dwyer DC, Prossnitz ER, Sklar LA. FRET detection of cellular alpha4-integrin conformational activation. Biophysical Journal. 85: 3951-62. PMID 14645084 DOI: 10.1016/S0006-3495(03)74809-7  0.681
2003 Simons PC, Shi M, Foutz T, Cimino DF, Lewis J, Buranda T, Lim WK, Neubig RR, McIntire WE, Garrison J, Prossnitz E, Sklar LA. Ligand-receptor-G-protein molecular assemblies on beads for mechanistic studies and screening by flow cytometry. Molecular Pharmacology. 64: 1227-38. PMID 14573773 DOI: 10.1124/Mol.64.5.1227  0.748
2003 Vines CM, Revankar CM, Maestas DC, LaRusch LL, Cimino DF, Kohout TA, Lefkowitz RJ, Prossnitz ER. N-formyl peptide receptors internalize but do not recycle in the absence of arrestins. The Journal of Biological Chemistry. 278: 41581-4. PMID 12947104 DOI: 10.1074/Jbc.C300291200  0.522
2003 Chigaev A, Zwartz G, Graves SW, Dwyer DC, Tsuji H, Foutz TD, Edwards BS, Prossnitz ER, Larson RS, Sklar LA. Alpha4beta1 integrin affinity changes govern cell adhesion. The Journal of Biological Chemistry. 278: 38174-82. PMID 12844491 DOI: 10.1074/Jbc.M210472200  0.676
2003 Prossnitz ER. Chemokines and chemokine receptors--Keystone Symposium 7-12 January 2003, Breckenridge, CO, USA. Idrugs : the Investigational Drugs Journal. 6: 191-4. PMID 12838978  0.376
2003 Shi M, Bennett TA, Cimino DF, Maestas DC, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Functional capabilities of an N-formyl peptide receptor-G(alpha)(i)(2) fusion protein: assemblies with G proteins and arrestins. Biochemistry. 42: 7283-93. PMID 12809484 DOI: 10.1021/Bi0341657  0.747
2003 Waller A, Simons P, Prossnitz ER, Edwards BS, Sklar LA. High throughput screening of G-protein coupled receptors via flow cytometry. Combinatorial Chemistry & High Throughput Screening. 6: 389-97. PMID 12769683 DOI: 10.2174/138620703106298482  0.724
2003 Key TA, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. N-formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity. The Journal of Biological Chemistry. 278: 4041-7. PMID 12424254 DOI: 10.1074/Jbc.M204687200  0.745
2003 Kasai R, Iino R, Fujiwara T, Nakanishi H, Prossnitz E, Kusumi A. Single molecule observations revealed new behaviors of G proteincoupled receptor after ligation Seibutsu Butsuri. 43: S158. DOI: 10.2142/Biophys.43.S158_1  0.417
2002 Vines CM, Xue M, Maestas DC, Cimino DF, Prossnitz ER. Regulation of N-formyl peptide-mediated degranulation by receptor phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 169: 6760-6. PMID 12471107 DOI: 10.4049/Jimmunol.169.12.6760  0.516
2002 Jackson WC, Bennett TA, Edwards BS, Prossnitz E, Lopez GP, Sklar LA. Performance of in-line microfluidic mixers in laminar flow for high-throughput flow cytometry. Biotechniques. 33: 220-6. PMID 12139249 DOI: 10.2144/02331Dd06  0.613
2002 Sklar LA, Edwards BS, Graves SW, Nolan JP, Prossnitz ER. Flow cytometric analysis of ligand-receptor interactions and molecular assemblies. Annual Review of Biophysics and Biomolecular Structure. 31: 97-119. PMID 11988464 DOI: 10.1146/Annurev.Biophys.31.082901.134406  0.675
2002 Potter RM, Key TA, Gurevich VV, Sklar LA, Prossnitz ER. Arrestin variants display differential binding characteristics for the phosphorylated N-formyl peptide receptor carboxyl terminus. The Journal of Biological Chemistry. 277: 8970-8. PMID 11777932 DOI: 10.1074/Jbc.M111086200  0.82
2002 Graham TE, Prossnitz ER, Dorin RI. Dexras1/AGS-1 inhibits signal transduction from the Gi-coupled formyl peptide receptor to Erk-1/2 MAP kinases. The Journal of Biological Chemistry. 277: 10876-82. PMID 11751935 DOI: 10.1074/Jbc.M110397200  0.493
2002 Kasai R, Iino R, Fujiwara T, Kobayashi T, Prossnitz E, Kusumi A. 3N1415 Single molecule imaging of trimeric G-Protein activation by a formyl peptide receptor Seibutsu Butsuri. 42: S197. DOI: 10.2142/Biophys.42.S197_4  0.435
2002 Prossnitz ER, Key TA, Potter RM, Gurevich VV, Slkar LA. S2L5 Mechanisms of arrestin interactions with G protein-coupled receptors Seibutsu Butsuri. 42: S12. DOI: 10.2142/Biophys.42.S12_1  0.479
2001 Edwards BS, Kuckuck FW, Prossnitz ER, Ransom JT, Sklar LA. HTPS flow cytometry: a novel platform for automated high throughput drug discovery and characterization. Journal of Biomolecular Screening. 6: 83-90. PMID 11689102 DOI: 10.1177/108705710100600204  0.635
2001 Chigaev A, Blenc AM, Braaten JV, Kumaraswamy N, Kepley CL, Andrews RP, Oliver JM, Edwards BS, Prossnitz ER, Larson RS, Sklar LA. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. The Journal of Biological Chemistry. 276: 48670-8. PMID 11641394 DOI: 10.1074/Jbc.M103194200  0.727
2001 Bennett TA, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Partial phosphorylation of the N-formyl peptide receptor inhibits G protein association independent of arrestin binding. The Journal of Biological Chemistry. 276: 49195-203. PMID 11602585 DOI: 10.1074/Jbc.M106414200  0.745
2001 Key TA, Bennett TA, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Regulation of formyl peptide receptor agonist affinity by reconstitution with arrestins and heterotrimeric G proteins. The Journal of Biological Chemistry. 276: 49204-12. PMID 11598142 DOI: 10.1074/Jbc.M109475200  0.763
2001 Bennett TA, Key TA, Gurevich VV, Neubig R, Prossnitz ER, Sklar LA. Real-time analysis of G protein-coupled receptor reconstitution in a solubilized system. The Journal of Biological Chemistry. 276: 22453-60. PMID 11309376 DOI: 10.1074/Jbc.M009679200  0.764
2001 Gilbert TL, Bennett TA, Maestas DC, Cimino DF, Prossnitz ER. Internalization of the human N-formyl peptide and C5a chemoattractant receptors occurs via clathrin-independent mechanisms. Biochemistry. 40: 3467-75. PMID 11297412 DOI: 10.1021/Bi001320Y  0.75
2001 Edwards BS, Kuckuck FW, Prossnitz ER, Okun A, Ransom JT, Sklar LA. Plug flow cytometry extends analytical capabilities in cell adhesion and receptor pharmacology. Cytometry. 43: 211-6. PMID 11170109 DOI: 10.1002/1097-0320(20010301)43:3<211::Aid-Cyto1052>3.0.Co;2-3  0.641
2001 Kasai R, Murakoshi H, Iino R, Fujiwara T, Nakanishi H, Yoshizumi R, Itami N, Kobayashi T, Haga T, Prossnitz E, Kusumi A. Localization mechanism for G protein-chemotactic receptor signaling : single molecule imaging of G-protein activation Seibutsu Butsuri. 41: S20. DOI: 10.2142/Biophys.41.S20_4  0.447
2001 Kasai R, Murakoshi H, Iino R, Fujiwara T, Nakanishi H, Yoshizumi R, Itami N, Kobayashi T, Haga T, Prossnitz E, Kusumi A. Single molecule analysis of G-protein-coupled chemotaxis Seibutsu Butsuri. 41: S120. DOI: 10.2142/Biophys.41.S120_4  0.347
2000 Burchiel SW, Edwards BS, Kuckuck FW, Lauer FT, Prossnitz ER, Ransom JT, Sklar LA. Analysis of free intracellular calcium by flow cytometry: multiparameter and pharmacologic applications. Methods (San Diego, Calif.). 21: 221-30. PMID 10873476 DOI: 10.1006/Meth.2000.1002  0.62
2000 Rane MJ, Prossnitz ER, Arthur JM, Ward RA, McLeish KR. Deficient homologous desensitization of formyl peptide receptors stably expressed in undifferentiated HL-60 cells. Biochemical Pharmacology. 60: 179-87. PMID 10825462 DOI: 10.1016/S0006-2952(00)00313-0  0.476
2000 Bennett TA, Maestas DC, Prossnitz ER. Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence. The Journal of Biological Chemistry. 275: 24590-4. PMID 10823817 DOI: 10.1074/Jbc.C000314200  0.541
2000 Sklar LA, Vilven J, Lynam E, Neldon D, Bennett TA, Prossnitz E. Solubilization and display of G protein-coupled receptors on beads for real-time fluorescence and flow cytometric analysis. Biotechniques. 28: 976-80, 982-5. PMID 10818705 DOI: 10.2144/00285Rr03  0.75
1999 Maestes DC, Potter RM, Prossnitz ER. Differential phosphorylation paradigms dictate desensitization and internalization of the N-formyl peptide receptor. The Journal of Biological Chemistry. 274: 29791-5. PMID 10514456 DOI: 10.1074/Jbc.274.42.29791  0.816
1999 Nolan JP, Lauer S, Prossnitz ER, Sklar LA. Flow cytometry: a versatile tool for all phases of drug discovery. Drug Discovery Today. 4: 173-180. PMID 10322276 DOI: 10.1016/S1359-6446(99)01320-3  0.607
1999 Gilbert TL, Prossnitz ER, Sklar LA. The uncoupled state of the human formyl peptide receptor. Journal of Receptor and Signal Transduction Research. 19: 327-40. PMID 10071768 DOI: 10.3109/10799899909036655  0.83
1999 Prossnitz ER, Gilbert TL, Chiang S, Campbell JJ, Qin S, Newman W, Sklar LA, Ye RD. Multiple activation steps of the N-formyl peptide receptor. Biochemistry. 38: 2240-7. PMID 10029516 DOI: 10.1021/Bi982274T  0.841
1998 Rane MJ, Arthur JM, Prossnitz ER, McLeish KR. Activation of mitogen-activated protein kinases by formyl peptide receptors is regulated by the cytoplasmic tail. The Journal of Biological Chemistry. 273: 20916-23. PMID 9694839 DOI: 10.1074/Jbc.273.33.20916  0.414
1998 Vilven JC, Domalewski M, Prossnitz ER, Ye RD, Muthukumaraswamy N, Harris RB, Freer RJ, Sklar LA. Strategies for positioning fluorescent probes and crosslinkers on formyl peptide ligands. Journal of Receptor and Signal Transduction Research. 18: 187-221. PMID 9651885 DOI: 10.3109/10799899809047744  0.691
1998 Hsu MH, Ember JA, Wang M, Prossnitz ER, Hugli TE, Ye RD. Cloning and functional characterization of the mouse C3a anaphylatoxin receptor gene. Immunogenetics. 47: 64-72. PMID 9382922 DOI: 10.1007/S002510050327  0.319
1998 Sklar LA, Seamer LC, Kuckuck F, Posner RG, Prossnitz E, Edwards B, Nolan JP. Sample handling for kinetics and molecular assembly in flow cytometry Proceedings of Spie - the International Society For Optical Engineering. 3256: 144-153. DOI: 10.1117/12.307057  0.562
1997 Hsu MH, Chiang SC, Ye RD, Prossnitz ER. Phosphorylation of the N-formyl peptide receptor is required for receptor internalization but not chemotaxis. The Journal of Biological Chemistry. 272: 29426-9. PMID 9367998 DOI: 10.1074/Jbc.272.47.29426  0.532
1997 Prossnitz ER, Ye RD. The N-formyl peptide receptor: A model for the study of chemoattractant receptor structure and function Pharmacology and Therapeutics. 74: 73-102. PMID 9336017 DOI: 10.1016/S0163-7258(96)00203-3  0.497
1997 Quehenberger O, Pan ZK, Prossnitz ER, Cavanagh SL, Cochrane CG, Ye RD. Identification of an N-formyl peptide receptor ligand binding domain by a gain-of-function approach Biochemical and Biophysical Research Communications. 238: 377-381. PMID 9299516 DOI: 10.1006/Bbrc.1997.7298  0.665
1997 Prossnitz ER. Desensitization of N-formylpeptide receptor-mediated activation is dependent upon receptor phosphorylation. The Journal of Biological Chemistry. 272: 15213-9. PMID 9182544 DOI: 10.1074/Jbc.272.24.15213  0.518
1997 Browning DD, Pan ZK, Prossnitz ER, Ye RD. Cell type- and developmental stage-specific activation of NF-κB by fMet-Leu-Phe in myeloid cells Journal of Biological Chemistry. 272: 7995-8001. PMID 9065470 DOI: 10.1074/Jbc.272.12.7995  0.336
1997 Kew RR, Peng T, DiMartino SJ, Madhavan D, Weinman SJ, Cheng D, Prossnitz ER. Undifferentiated U937 cells transfected with chemoattractant receptors: a model system to investigate chemotactic mechanisms and receptor structure/function relationships. Journal of Leukocyte Biology. 61: 329-37. PMID 9060456 DOI: 10.1002/Jlb.61.3.329  0.5
1996 Pan ZK, Zuraw BL, Lung CC, Prossnitz ER, Browning DD, Ye RD. Bradykinin stimulates NF-κB activation and interleukin 1β gene expression in cultured human fibroblasts Journal of Clinical Investigation. 98: 2042-2049. PMID 8903323 DOI: 10.1172/Jci119009  0.348
1996 Ptasznik A, Prossnitz ER, Yoshikawa D, Smrcka A, Traynor-Kaplan AE, Bokoch GM. A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphosphate formation in chemoattractant-stimulated human neutrophils. The Journal of Biological Chemistry. 271: 25204-7. PMID 8810279 DOI: 10.1074/Jbc.271.41.25204  0.37
1996 Roglić A, Prossnitz ER, Cavanagh SL, Pan Z, Zou A, Ye RD. cDNA cloning of a novel G protein-coupled receptor with a large extracellular loop structure Biochimica Et Biophysica Acta - Gene Structure and Expression. 1305: 39-43. PMID 8605247 DOI: 10.1016/0167-4781(95)00209-X  0.481
1995 Prossnitz ER, Kim CM, Benovic JL, Ye RD. Phosphorylation of the N-formyl peptide receptor carboxyl terminus by the G protein-coupled receptor kinase, GRK2 Journal of Biological Chemistry. 270: 1130-1137. PMID 7836371 DOI: 10.1074/Jbc.270.3.1130  0.422
1995 Prossnitz ER, Schreiber RE, Bokoch GM, Ye RD. Binding of low affinity N-formyl peptide receptors to G protein. Characterization of a novel inactive receptor intermediate. The Journal of Biological Chemistry. 270: 10686-94. PMID 7738006 DOI: 10.1074/Jbc.270.18.10686  0.533
1994 Schreiber RE, Prossnitz ER, Ye RD, Cochrane CG, Bokoch GM. Domains of the human neutrophil N-formyl peptide receptor involved in G protein coupling. Mapping with receptor-derived peptides. The Journal of Biological Chemistry. 269: 326-31. PMID 8276814  0.421
1993 Schreiber RE, Prossnitz ER, Ye RD, Cochrane CG, Jesaitis AJ, Bokoch GM. Reconstitution of recombinant N-formyl chemotactic peptide receptor with G protein Journal of Leukocyte Biology. 53: 470-474. PMID 8482927 DOI: 10.1002/Jlb.53.4.470  0.675
1993 Ye RD, Quehenberger O, Thomas KM, Navarro J, Cavanagh SL, Prossnitz ER, Cochrane CG. The rabbit neutrophil N-formyl peptide receptor: cDNA cloning, expression, and structure/function implications Journal of Immunology. 150: 1383-1394. PMID 8432984  0.357
1993 Prossnitz ER, Quehenberger O, Cochrane CG, Ye RD. The role of the third intracellular loop of the neutrophil N-formyl peptide receptor in G protein coupling. The Biochemical Journal. 294: 581-7. PMID 8373373 DOI: 10.1042/Bj2940581  0.693
1993 Quehenberger O, Prossnitz ER, Cavanagh SL, Cochrane CG, Ye RD. Multiple domains of the N-formyl peptide receptor are required for high-affinity ligand binding: Construction and analysis of chimeric N-formyl peptide receptors Journal of Biological Chemistry. 268: 18167-18175. PMID 8349692  0.356
1993 Prossnitz ER, Quehenberger O, Cochrane CG, Ye RD. Signal transducing properties of the N-formyl peptide receptor expressed in undifferentiated HL60 cells. Journal of Immunology (Baltimore, Md. : 1950). 151: 5704-15. PMID 8228256  0.32
1992 Quehenberger O, Prossnitz ER, Cochrane CG, Ye RD. Absence of G(i) proteins in the Sf9 insect cell. Characterization of the uncoupled recombinant N-formyl peptide receptor. The Journal of Biological Chemistry. 267: 19757-60. PMID 1400288  0.424
1992 Ye RD, Cavanagh SL, Quehenberger O, Prossnitz ER, Cochrane CG. Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor Biochemical and Biophysical Research Communications. 184: 582-589. PMID 1374236 DOI: 10.1016/0006-291X(92)90629-Y  0.669
1991 Prossnitz ER, Quehenberger O, Cochrane CG, Ye RD. Transmembrane signalling by the N-formyl peptide receptor in stably transfected fibroblasts. Biochemical and Biophysical Research Communications. 179: 471-6. PMID 1883372 DOI: 10.1016/0006-291X(91)91394-R  0.678
1991 Ye RD, Prossnitz ER, Zou AH, Cochrane CG. Characterization of a human cDNA that encodes a functional receptor for platelet activating factor. Biochemical and Biophysical Research Communications. 180: 105-11. PMID 1656963 DOI: 10.1016/S0006-291X(05)81261-6  0.672
1989 Prossnitz E, Gee A, Ames GF. Reconstitution of the histidine periplasmic transport system in membrane vesicles. Energy coupling and interaction between the binding protein and the membrane complex. The Journal of Biological Chemistry. 264: 5006-14. PMID 2647746  0.559
1988 Stern MJ, Prossnitz E, Ames GF. Role of the intercistronic region in post-transcriptional control of gene expression in the histidine transport operon of Salmonella typhimurium: involvement of REP sequences. Molecular Microbiology. 2: 141-52. PMID 3130541 DOI: 10.1111/J.1365-2958.1988.Tb00015.X  0.58
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