| Year |
Citation |
Score |
| 2023 |
Lucaciu SA, Leighton SE, Hauser A, Yee R, Laird DW. Diversity in Connexin Biology. The Journal of Biological Chemistry. 105263. PMID 37734551 DOI: 10.1016/j.jbc.2023.105263 |
0.362 |
|
| 2023 |
Lucaciu SA, Figliuzzi R, Neumann R, Nazarali S, Del Sordo L, Leighton SE, Hauser A, Shao Q, Johnston D, Bai D, Laird DW. variants linked to skin disease exhibit a trafficking deficiency en route to gap junction formation that can be restored by co-expression of select connexins. Frontiers in Cell and Developmental Biology. 11: 1073805. PMID 36861039 DOI: 10.3389/fcell.2023.1073805 |
0.347 |
|
| 2022 |
Lampe PD, Laird DW. Recent advances in connexin gap junction biology. Faculty Reviews. 11: 14. PMID 35693635 DOI: 10.12703/r/11-14 |
0.323 |
|
| 2022 |
Lucaciu SA, Shao Q, Figliuzzi R, Barr K, Bai D, Laird DW. Interrogation of Carboxy-Terminus Localized Variants Associated with Erythrokeratodermia Variabilis et Progressiva. International Journal of Molecular Sciences. 23. PMID 35008913 DOI: 10.3390/ijms23010486 |
0.338 |
|
| 2020 |
Au A, Shao Q, White KK, Lucaciu SA, Esseltine JL, Barr K, Laird DW. Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes. Biomolecules. 10. PMID 33066499 DOI: 10.3390/biom10101443 |
0.366 |
|
| 2020 |
Moore AC, Wu J, Jewlal E, Barr K, Laird DW, Willmore KE. Effects of Reduced Connexin43 Function on Mandibular Morphology and Osteogenesis in Mutant Mouse Models of Oculodentodigital Dysplasia. Calcified Tissue International. PMID 32902679 DOI: 10.1007/S00223-020-00753-9 |
0.374 |
|
| 2020 |
Abitbol J, Beach R, Barr K, Esseltine J, Allman B, Laird D. Cisplatin-induced ototoxicity in organotypic cochlear cultures occurs independent of gap junctional intercellular communication. Cell Death & Disease. 11: 342. PMID 32393745 DOI: 10.1038/S41419-020-2551-8 |
0.451 |
|
| 2020 |
Jarvis SE, Lee JE, Jewlal E, Barr K, Kelly GM, Laird DW, Willmore KE. Effects of reduced connexin43 function on skull development in the Cx43 mutant mouse that models oculodentodigital dysplasia. Bone. 115365. PMID 32320893 DOI: 10.1016/J.Bone.2020.115365 |
0.353 |
|
| 2020 |
Beach R, Abitbol JM, Allman BL, Esseltine JL, Shao Q, Laird DW. Mutations Linked to Hearing Loss Exhibit Differential Trafficking and Functional Defects as Revealed in Cochlear-Relevant Cells. Frontiers in Cell and Developmental Biology. 8: 215. PMID 32300592 DOI: 10.3389/Fcell.2020.00215 |
0.475 |
|
| 2020 |
Chepied A, Daoud-Omar Z, Meunier-Balandre AC, Laird DW, Mesnil M, Defamie N. Involvement of the Gap Junction Protein, Connexin43, in the Formation and Function of Invadopodia in the Human U251 Glioblastoma Cell Line. Cells. 9. PMID 31947771 DOI: 10.3390/Cells9010117 |
0.429 |
|
| 2019 |
Esseltine JL, Brooks CR, Edwards NA, Subasri M, Sampson J, Séguin C, Betts DH, Laird DW. Dynamic regulation of connexins in stem cell pluripotency. Stem Cells (Dayton, Ohio). PMID 31646713 DOI: 10.1002/Stem.3092 |
0.326 |
|
| 2019 |
Shum MG, Shao Q, Lajoie P, Laird DW. Destination and consequences of Panx1 and mutant expression in polarized MDCK cells. Experimental Cell Research. PMID 31102595 DOI: 10.1016/J.Yexcr.2019.05.016 |
0.415 |
|
| 2019 |
Novielli-Kuntz NM, Jelen M, Barr K, Delailo LJ, Feng Q, Isakson BE, Gros R, Laird DW. Ablation of both Cx40 and Panx1 results in similar cardiovascular phenotypes exhibited in Cx40 knockout mice. Bioscience Reports. PMID 30745457 DOI: 10.1042/Bsr20182350 |
0.364 |
|
| 2019 |
Kelly JJ, Abitbol JM, Hulme S, Press ER, Laird DW, Allman BL. The connexin 30 A88V mutant reduces cochlear gap junction expression and confers long-term protection against hearing loss. Journal of Cell Science. 132. PMID 30559251 DOI: 10.1242/Jcs.224097 |
0.425 |
|
| 2018 |
Laird DW, Lampe PD. Therapeutic strategies targeting connexins. Nature Reviews. Drug Discovery. PMID 30310236 DOI: 10.1038/Nrd.2018.138 |
0.394 |
|
| 2018 |
Abitbol JM, Kelly JJ, Barr KJ, Allman BL, Laird DW. Mice harbouring an oculodentodigital dysplasia-linked Cx43 G60S mutation have severe hearing loss. Journal of Cell Science. PMID 29618634 DOI: 10.1242/Jcs.214635 |
0.324 |
|
| 2017 |
Leybaert L, Lampe PD, Dhein S, Kwak BR, Ferdinandy P, Beyer EC, Laird DW, Naus CC, Green CR, Schulz R. Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications. Pharmacological Reviews. 69: 396-478. PMID 28931622 DOI: 10.1124/Pr.115.012062 |
0.419 |
|
| 2017 |
Laird DW, Naus CC, Lampe PD. SnapShot: Connexins and Disease. Cell. 170: 1260-1260.e1. PMID 28886388 DOI: 10.1016/J.Cell.2017.08.034 |
0.44 |
|
| 2017 |
Delmar M, Laird DW, Naus CC, Nielsen MS, Verselis VK, White TW. Connexins and Disease. Cold Spring Harbor Perspectives in Biology. PMID 28778872 DOI: 10.1101/Cshperspect.A029348 |
0.342 |
|
| 2017 |
Mesnil M, Aasen T, Boucher J, Chépied A, Cronier L, Defamie N, Kameritsch P, Laird DW, Lampe PD, Lathia JD, Leithe E, Mehta PP, Monvoisin A, Pogoda K, Sin WC, et al. An update on minding the gap in cancer. Biochimica Et Biophysica Acta. PMID 28655619 DOI: 10.1016/J.Bbamem.2017.06.015 |
0.318 |
|
| 2017 |
Alaga KC, Crawford M, Dagnino L, Laird DW. Aberrant Cx43 Expression and Mislocalization in Metastatic Human Melanomas. Journal of Cancer. 8: 1123-1128. PMID 28607585 DOI: 10.7150/Jca.18569 |
0.438 |
|
| 2017 |
Press E, Alaga KC, Barr K, Shao Q, Bosen F, Willecke K, Laird DW. Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice. Cell Death & Disease. 8: e2845. PMID 28569788 DOI: 10.1038/Cddis.2017.234 |
0.375 |
|
| 2017 |
Press ER, Shao Q, Kelly JJ, Chin K, Alaga A, Laird DW. Induction of cell death and gain-of-function properties of connexin26 mutants predict severity of skin disorders and hearing loss. The Journal of Biological Chemistry. PMID 28428247 DOI: 10.1074/Jbc.M116.770917 |
0.464 |
|
| 2017 |
Esseltine JL, Shao Q, Brooks C, Sampson J, Betts DH, Séguin C, Laird DW. Connexin43 Mutant Patient-Derived Induced Pluripotent Stem Cells Exhibit Altered Differentiation Potential. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28177159 DOI: 10.1002/Jbmr.3098 |
0.394 |
|
| 2016 |
Aasen T, Mesnil M, Naus CC, Lampe PD, Laird DW. Gap junctions and cancer: communicating for 50 years. Nature Reviews. Cancer. PMID 27782134 DOI: 10.1038/Nrc.2016.105 |
0.372 |
|
| 2016 |
Johnson RG, Le HC, Evenson K, Loberg SW, Myslajek TM, Prabhu A, Manley AM, O'Shea C, Grunenwald H, Haddican M, Fitzgerald PM, Robinson T, Cisterna BA, Sáez JC, Liu TF, ... Laird DW, et al. Connexin Hemichannels: Methods for Dye Uptake and Leakage. The Journal of Membrane Biology. PMID 27586664 DOI: 10.1007/S00232-016-9925-Y |
0.409 |
|
| 2016 |
Esseltine JL, Laird DW. Next-Generation Connexin and Pannexin Cell Biology. Trends in Cell Biology. PMID 27339936 DOI: 10.1016/J.Tcb.2016.06.003 |
0.401 |
|
| 2016 |
Plotkin LI, Laird DW, Amedee J. Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone. Bmc Cell Biology. 17: 19. PMID 27230612 DOI: 10.1186/S12860-016-0088-6 |
0.317 |
|
| 2016 |
Kelly JJ, Esseltine J, Shao Q, Jabs EW, Sampson J, Auranen M, Bai D, Laird DW. Specific functional pathologies of Cx43 mutations associated with oculodentodigital dysplasia. Molecular Biology of the Cell. PMID 27226478 DOI: 10.1091/Mbc.E16-01-0062 |
0.414 |
|
| 2016 |
Siddiqui M, Swarbreck S, Shao Q, Secor D, Peng T, Laird DW, Tyml K. Critical Role of Cx40 in Reduced Endothelial Electrical Coupling by Lipopolysaccharide and Hypoxia-Reoxygenation. Journal of Vascular Research. 52: 396-403. PMID 27194161 DOI: 10.1159/000445772 |
0.34 |
|
| 2016 |
Shao Q, Lindstrom K, Shi R, Kelly J, Schroeder A, Juusola J, Levine KL, Esseltine JL, Penuela S, Jackson MF, Laird DW. A germline variant in PANX1 has reduced channel function and is associated with multisystem dysfunction. The Journal of Biological Chemistry. PMID 27129271 DOI: 10.1074/Jbc.M116.717934 |
0.409 |
|
| 2016 |
Stewart MK, Plante I, Penuela S, Laird DW. Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis. Plos One. 11: e0154162. PMID 27099931 DOI: 10.1371/Journal.Pone.0154162 |
0.346 |
|
| 2016 |
Laird DW, Naus CC. Gerald M. Kidder - bridging the gap in cell and developmental biology. Seminars in Cell & Developmental Biology. 50: 1-3. PMID 26940063 DOI: 10.1016/J.Semcdb.2016.02.017 |
0.315 |
|
| 2016 |
Caskenette D, Penuela S, Lee V, Barr K, Beier F, Laird DW, Willmore KE. Global deletion of Panx3 produces multiple phenotypic effects in mouse humeri and femora. Journal of Anatomy. 228: 746-56. PMID 26749194 DOI: 10.1111/Joa.12437 |
0.319 |
|
| 2016 |
Merrifield PA, Laird DW. Connexins in skeletal muscle development and disease. Seminars in Cell & Developmental Biology. 50: 67-73. PMID 26688333 DOI: 10.1016/J.Semcdb.2015.12.001 |
0.317 |
|
| 2015 |
Stewart MK, Bechberger JF, Welch I, Naus CC, Laird DW. Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer. Oncotarget. 6: 37185-99. PMID 26439696 DOI: 10.18632/Oncotarget.5953 |
0.33 |
|
| 2015 |
Kelly JJ, Shao Q, Jagger DJ, Laird DW. Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions. Journal of Cell Science. PMID 26359304 DOI: 10.1242/Jcs.174698 |
0.486 |
|
| 2015 |
Esseltine JL, Shao Q, Huang T, Kelly JJ, Sampson J, Laird DW. Manipulating Cx43 expression triggers gene reprogramming events in dermal fibroblasts from oculodentodigital dysplasia patients. The Biochemical Journal. PMID 26349540 DOI: 10.1042/Bj20150652 |
0.423 |
|
| 2015 |
Laird DW, Lampe PD, Johnson RG. CELLULAR SMALL TALK. Scientific American. 312: 70-7. PMID 26336714 DOI: 10.1038/Scientificamerican0515-70 |
0.412 |
|
| 2015 |
Moon PM, Penuela S, Barr K, Khan S, Pin CL, Welch I, Attur M, Abramson SB, Laird DW, Beier F. Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis. Journal of Molecular Medicine (Berlin, Germany). PMID 26138248 DOI: 10.1007/S00109-015-1311-1 |
0.311 |
|
| 2015 |
Stewart MK, Simek J, Laird DW. Insights into the role of connexins in mammary gland morphogenesis and function. Reproduction (Cambridge, England). 149: R279-90. PMID 25792566 DOI: 10.1530/Rep-14-0661 |
0.437 |
|
| 2015 |
Kelly JJ, Simek J, Laird DW. Mechanisms linking connexin mutations to human diseases. Cell and Tissue Research. 360: 701-21. PMID 25398718 DOI: 10.1007/S00441-014-2024-4 |
0.39 |
|
| 2014 |
Xiao D, Chen S, Shao Q, Chen J, Bijian K, Laird DW, Alaoui-Jamali MA. Dynamin 2 interacts with connexin 26 to regulate its degradation and function in gap junction formation. The International Journal of Biochemistry & Cell Biology. 55: 288-97. PMID 25263585 DOI: 10.1016/J.Biocel.2014.09.021 |
0.451 |
|
| 2014 |
Boyd-Tressler A, Penuela S, Laird DW, Dubyak GR. Chemotherapeutic drugs induce ATP release via caspase-gated pannexin-1 channels and a caspase/pannexin-1-independent mechanism. The Journal of Biological Chemistry. 289: 27246-63. PMID 25112874 DOI: 10.1074/Jbc.M114.590240 |
0.323 |
|
| 2014 |
Penuela S, Harland L, Simek J, Laird DW. Pannexin channels and their links to human disease. The Biochemical Journal. 461: 371-81. PMID 25008946 DOI: 10.1042/Bj20140447 |
0.352 |
|
| 2014 |
Stewart MK, Plante I, Bechberger JF, Naus CC, Laird DW. Mammary gland specific knockdown of the physiological surge in Cx26 during lactation retains normal mammary gland development and function. Plos One. 9: e101546. PMID 24988191 DOI: 10.1371/Journal.Pone.0101546 |
0.395 |
|
| 2014 |
Sun Y, Tong X, Chen H, Huang T, Shao Q, Huang W, Laird DW, Bai D. An atrial-fibrillation-linked connexin40 mutant is retained in the endoplasmic reticulum and impairs the function of atrial gap-junction channels. Disease Models & Mechanisms. 7: 561-9. PMID 24626989 DOI: 10.1242/Dmm.013813 |
0.473 |
|
| 2014 |
Penuela S, Kelly JJ, Churko JM, Barr KJ, Berger AC, Laird DW. Panx1 regulates cellular properties of keratinocytes and dermal fibroblasts in skin development and wound healing. The Journal of Investigative Dermatology. 134: 2026-35. PMID 24522432 DOI: 10.1038/Jid.2014.86 |
0.319 |
|
| 2014 |
Berger AC, Kelly JJ, Lajoie P, Shao Q, Laird DW. Mutations in Cx30 that are linked to skin disease and non-syndromic hearing loss exhibit several distinct cellular pathologies. Journal of Cell Science. 127: 1751-64. PMID 24522190 DOI: 10.1242/Jcs.138230 |
0.41 |
|
| 2014 |
Laird DW. Syndromic and non-syndromic disease-linked Cx43 mutations. Febs Letters. 588: 1339-48. PMID 24434540 DOI: 10.1016/J.Febslet.2013.12.022 |
0.326 |
|
| 2014 |
Penuela S, Lohman AW, Lai W, Gyenis L, Litchfield DW, Isakson BE, Laird DW. Diverse post-translational modifications of the pannexin family of channel-forming proteins. Channels (Austin, Tex.). 8: 124-30. PMID 24418849 DOI: 10.4161/Chan.27422 |
0.384 |
|
| 2014 |
Ableser MJ, Penuela S, Lee J, Shao Q, Laird DW. Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesis in vivo. The Journal of Biological Chemistry. 289: 1592-603. PMID 24297173 DOI: 10.1074/Jbc.M113.507228 |
0.472 |
|
| 2014 |
Huang T, Shao Q, Barr K, Simek J, Fishman GI, Laird DW. Myogenic bladder defects in mouse models of human oculodentodigital dysplasia. The Biochemical Journal. 457: 441-9. PMID 24228978 DOI: 10.1042/Bj20130810 |
0.375 |
|
| 2014 |
Shao QC, Ableser MJ, Penuela S, Laird DW. Abstract 2467: Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesisin vivo Cancer Research. 74: 2467-2467. DOI: 10.1158/1538-7445.Am2014-2467 |
0.475 |
|
| 2013 |
Churko JM, Laird DW. Gap junction remodeling in skin repair following wounding and disease. Physiology (Bethesda, Md.). 28: 190-8. PMID 23636264 DOI: 10.1152/Physiol.00058.2012 |
0.314 |
|
| 2013 |
Huang T, Shao Q, MacDonald A, Xin L, Lorentz R, Bai D, Laird DW. Autosomal recessive GJA1 (Cx43) gene mutations cause oculodentodigital dysplasia by distinct mechanisms. Journal of Cell Science. 126: 2857-66. PMID 23606748 DOI: 10.1242/Jcs.123315 |
0.49 |
|
| 2013 |
Stewart MK, Gong XQ, Barr KJ, Bai D, Fishman GI, Laird DW. The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice. The Biochemical Journal. 449: 401-13. PMID 23075222 DOI: 10.1042/Bj20121070 |
0.405 |
|
| 2013 |
Kranz K, Dorgau B, Pottek M, Herrling R, Schultz K, Bolte P, Monyer H, Penuela S, Laird DW, Dedek K, Weiler R, Janssen-Bienhold U. Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout. The Journal of Comparative Neurology. 521: 1119-35. PMID 22965528 DOI: 10.1002/Cne.23223 |
0.437 |
|
| 2013 |
Penuela S, Gehi R, Laird DW. The biochemistry and function of pannexin channels. Biochimica Et Biophysica Acta. 1828: 15-22. PMID 22305965 DOI: 10.1016/J.Bbamem.2012.01.017 |
0.408 |
|
| 2012 |
Lohman AW, Weaver JL, Billaud M, Sandilos JK, Griffiths R, Straub AC, Penuela S, Leitinger N, Laird DW, Bayliss DA, Isakson BE. S-nitrosylation inhibits pannexin 1 channel function. The Journal of Biological Chemistry. 287: 39602-12. PMID 23033481 DOI: 10.1074/Jbc.M112.397976 |
0.325 |
|
| 2012 |
Cowan KN, Langlois S, Penuela S, Cowan BJ, Laird DW. Pannexin1 and Pannexin3 exhibit distinct localization patterns in human skin appendages and are regulated during keratinocyte differentiation and carcinogenesis. Cell Communication & Adhesion. 19: 45-53. PMID 22947051 DOI: 10.3109/15419061.2012.712575 |
0.326 |
|
| 2012 |
Shao Q, Liu Q, Lorentz R, Gong XQ, Bai D, Shaw GS, Laird DW. Structure and functional studies of N-terminal Cx43 mutants linked to oculodentodigital dysplasia. Molecular Biology of the Cell. 23: 3312-21. PMID 22809623 DOI: 10.1091/Mbc.E12-02-0128 |
0.385 |
|
| 2012 |
Churko JM, Kelly JJ, Macdonald A, Lee J, Sampson J, Bai D, Laird DW. The G60S Cx43 mutant enhances keratinocyte proliferation and differentiation. Experimental Dermatology. 21: 612-8. PMID 22775996 DOI: 10.1111/J.1600-0625.2012.01532.X |
0.432 |
|
| 2012 |
Penuela S, Gyenis L, Ablack A, Churko JM, Berger AC, Litchfield DW, Lewis JD, Laird DW. Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype. The Journal of Biological Chemistry. 287: 29184-93. PMID 22753409 DOI: 10.1074/Jbc.M112.377176 |
0.414 |
|
| 2012 |
Lorentz R, Shao Q, Huang T, Fishman GI, Laird DW. Characterization of gap junction proteins in the bladder of Cx43 mutant mouse models of oculodentodigital dysplasia. The Journal of Membrane Biology. 245: 345-55. PMID 22752022 DOI: 10.1007/S00232-012-9455-1 |
0.391 |
|
| 2012 |
Pocrnich CE, Shao Q, Liu H, Feng MM, Harasym S, Savage M, Khimdas S, Laird DW, Hutnik CM. The effect of connexin43 on the level of vascular endothelial growth factor in human retinal pigment epithelial cells. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fã¼R Klinische Und Experimentelle Ophthalmologie. 250: 515-22. PMID 22138732 DOI: 10.1007/S00417-011-1871-X |
0.337 |
|
| 2011 |
Bond SR, Lau A, Penuela S, Sampaio AV, Underhill TM, Laird DW, Naus CC. Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2911-22. PMID 21915903 DOI: 10.1002/Jbmr.509 |
0.339 |
|
| 2011 |
Plante I, Stewart MK, Laird DW. Evaluation of mammary gland development and function in mouse models. Journal of Visualized Experiments : Jove. PMID 21808224 DOI: 10.3791/2828 |
0.373 |
|
| 2011 |
Churko JM, Chan J, Shao Q, Laird DW. The G60S connexin43 mutant regulates hair growth and hair fiber morphology in a mouse model of human oculodentodigital dysplasia. The Journal of Investigative Dermatology. 131: 2197-204. PMID 21716323 DOI: 10.1038/Jid.2011.183 |
0.354 |
|
| 2011 |
Gehi R, Shao Q, Laird DW. Pathways regulating the trafficking and turnover of pannexin1 protein and the role of the C-terminal domain. The Journal of Biological Chemistry. 286: 27639-53. PMID 21659516 DOI: 10.1074/Jbc.M111.260711 |
0.384 |
|
| 2011 |
Seminario-Vidal L, Okada SF, Sesma JI, Kreda SM, van Heusden CA, Zhu Y, Jones LC, O'Neal WK, Penuela S, Laird DW, Boucher RC, Lazarowski ER. Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia. The Journal of Biological Chemistry. 286: 26277-86. PMID 21606493 DOI: 10.1074/Jbc.M111.260562 |
0.331 |
|
| 2011 |
Billaud M, Lohman AW, Straub AC, Looft-Wilson R, Johnstone SR, Araj CA, Best AK, Chekeni FB, Ravichandran KS, Penuela S, Laird DW, Isakson BE. Pannexin1 regulates α1-adrenergic receptor- mediated vasoconstriction. Circulation Research. 109: 80-5. PMID 21546608 DOI: 10.1161/Circresaha.110.237594 |
0.309 |
|
| 2011 |
Sosinsky GE, Boassa D, Dermietzel R, Duffy HS, Laird DW, MacVicar B, Naus CC, Penuela S, Scemes E, Spray DC, Thompson RJ, Zhao HB, Dahl G. Pannexin channels are not gap junction hemichannels. Channels (Austin, Tex.). 5: 193-7. PMID 21532340 DOI: 10.4161/Chan.5.3.15765 |
0.383 |
|
| 2011 |
Turmel P, Dufresne J, Hermo L, Smith CE, Penuela S, Laird DW, Cyr DG. Characterization of pannexin1 and pannexin3 and their regulation by androgens in the male reproductive tract of the adult rat. Molecular Reproduction and Development. 78: 124-38. PMID 21337450 DOI: 10.1002/Mrd.21280 |
0.446 |
|
| 2011 |
Churko JM, Shao Q, Gong XQ, Swoboda KJ, Bai D, Sampson J, Laird DW. Human dermal fibroblasts derived from oculodentodigital dysplasia patients suggest that patients may have wound-healing defects. Human Mutation. 32: 456-66. PMID 21305658 DOI: 10.1002/Humu.21472 |
0.404 |
|
| 2011 |
Tsui E, Hill KA, Laliberte AM, Paluzzi D, Kisilevsky I, Shao Q, Heathcote JG, Laird DW, Kidder GM, Hutnik CM. Ocular pathology relevant to glaucoma in a Gja1(Jrt/+) mouse model of human oculodentodigital dysplasia. Investigative Ophthalmology & Visual Science. 52: 3539-47. PMID 21273537 DOI: 10.1167/Iovs.10-6399 |
0.334 |
|
| 2011 |
Plante I, Stewart MK, Barr K, Allan AL, Laird DW. Cx43 suppresses mammary tumor metastasis to the lung in a Cx43 mutant mouse model of human disease. Oncogene. 30: 1681-92. PMID 21151177 DOI: 10.1038/Onc.2010.551 |
0.33 |
|
| 2011 |
Sandilos JK, Chekeni FB, Elliott MR, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, Isakson BE, Ravichandran KS, Bayliss DA. Caspases Mediate Pannexin 1 Channel Activation in Apoptotic Cells Biophysical Journal. 100: 101a. DOI: 10.1016/J.Bpj.2010.12.759 |
0.394 |
|
| 2010 |
Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, Isakson BE, Bayliss DA, Ravichandran KS. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature. 467: 863-7. PMID 20944749 DOI: 10.1038/Nature09413 |
0.334 |
|
| 2010 |
Yu G, Bolon M, Laird DW, Tyml K. Hypoxia and reoxygenation-induced oxidant production increase in microvascular endothelial cells depends on connexin40. Free Radical Biology & Medicine. 49: 1008-13. PMID 20541007 DOI: 10.1016/J.Freeradbiomed.2010.06.005 |
0.391 |
|
| 2010 |
Churko JM, Langlois S, Pan X, Shao Q, Laird DW. The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants. The Biochemical Journal. 429: 473-83. PMID 20515445 DOI: 10.1042/Bj20100155 |
0.383 |
|
| 2010 |
Naus CC, Laird DW. Implications and challenges of connexin connections to cancer. Nature Reviews. Cancer. 10: 435-41. PMID 20495577 DOI: 10.1038/Nrc2841 |
0.372 |
|
| 2010 |
Langlois S, Cowan KN, Shao Q, Cowan BJ, Laird DW. The tumor-suppressive function of Connexin43 in keratinocytes is mediated in part via interaction with caveolin-1. Cancer Research. 70: 4222-32. PMID 20406988 DOI: 10.1158/0008-5472.Can-09-3281 |
0.381 |
|
| 2010 |
Celetti SJ, Cowan KN, Penuela S, Shao Q, Churko J, Laird DW. Implications of pannexin 1 and pannexin 3 for keratinocyte differentiation. Journal of Cell Science. 123: 1363-72. PMID 20332104 DOI: 10.1242/Jcs.056093 |
0.457 |
|
| 2010 |
Plante I, Wallis A, Shao Q, Laird DW. Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged. Biology of Reproduction. 82: 837-47. PMID 20089884 DOI: 10.1095/Biolreprod.109.081406 |
0.448 |
|
| 2010 |
Bhalla-Gehi R, Penuela S, Churko JM, Shao Q, Laird DW. Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions. The Journal of Biological Chemistry. 285: 9147-60. PMID 20086016 DOI: 10.1074/Jbc.M109.082008 |
0.461 |
|
| 2010 |
Laird DW. The gap junction proteome and its relationship to disease. Trends in Cell Biology. 20: 92-101. PMID 19944606 DOI: 10.1016/J.Tcb.2009.11.001 |
0.426 |
|
| 2010 |
Langlois S, Churko JM, Laird DW. Optical and biochemical dissection of connexin and disease-linked connexin mutants in 3D organotypic epidermis. Methods in Molecular Biology (Clifton, N.J.). 585: 313-34. PMID 19908013 DOI: 10.1007/978-1-60761-380-0_22 |
0.386 |
|
| 2010 |
Plante I, Barr K, Stewart MKG, Allan A, Laird DW. Abstract 474: Cx43 mutant mice show delayed formation of palpable mammary gland tumors but are more susceptible to lung lesions Cancer Research. 70: 474-474. DOI: 10.1158/1538-7445.Am10-474 |
0.308 |
|
| 2009 |
Penuela S, Bhalla R, Nag K, Laird DW. Glycosylation regulates pannexin intermixing and cellular localization. Molecular Biology of the Cell. 20: 4313-23. PMID 19692571 DOI: 10.1091/Mbc.E09-01-0067 |
0.442 |
|
| 2009 |
Tong D, Colley D, Thoo R, Li TY, Plante I, Laird DW, Bai D, Kidder GM. Oogenesis defects in a mutant mouse model of oculodentodigital dysplasia. Disease Models & Mechanisms. 2: 157-67. PMID 19259389 DOI: 10.1242/Dmm.000935 |
0.428 |
|
| 2009 |
Tong D, Lu X, Wang HX, Plante I, Lui E, Laird DW, Bai D, Kidder GM. A dominant loss-of-function GJA1 (Cx43) mutant impairs parturition in the mouse. Biology of Reproduction. 80: 1099-106. PMID 19176884 DOI: 10.1095/Biolreprod.108.071969 |
0.442 |
|
| 2009 |
Simek J, Churko J, Shao Q, Laird DW. Cx43 has distinct mobility within plasma-membrane domains, indicative of progressive formation of gap-junction plaques. Journal of Cell Science. 122: 554-62. PMID 19174466 DOI: 10.1242/Jcs.036970 |
0.42 |
|
| 2008 |
Manias JL, Plante I, Gong XQ, Shao Q, Churko J, Bai D, Laird DW. Fate of connexin43 in cardiac tissue harbouring a disease-linked connexin43 mutant. Cardiovascular Research. 80: 385-95. PMID 18678643 DOI: 10.1093/Cvr/Cvn203 |
0.338 |
|
| 2008 |
Penuela S, Celetti SJ, Bhalla R, Shao Q, Laird DW. Diverse subcellular distribution profiles of pannexin 1 and pannexin 3. Cell Communication & Adhesion. 15: 133-42. PMID 18649185 DOI: 10.1080/15419060802014115 |
0.479 |
|
| 2008 |
Plante I, Laird DW. Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia. Developmental Biology. 318: 312-22. PMID 18455714 DOI: 10.1016/J.Ydbio.2008.03.033 |
0.424 |
|
| 2008 |
McLachlan E, Plante I, Shao Q, Tong D, Kidder GM, Bernier SM, Laird DW. ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 928-38. PMID 18269311 DOI: 10.1359/Jbmr.080217 |
0.367 |
|
| 2008 |
Hutnik CM, Pocrnich CE, Liu H, Laird DW, Shao Q. The protective effect of functional connexin43 channels on a human epithelial cell line exposed to oxidative stress. Investigative Ophthalmology & Visual Science. 49: 800-6. PMID 18235030 DOI: 10.1167/Iovs.07-0717 |
0.354 |
|
| 2008 |
Langlois S, Cowan KN, Shao Q, Cowan BJ, Laird DW. Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes. Molecular Biology of the Cell. 19: 912-28. PMID 18162583 DOI: 10.1091/Mbc.E07-06-0596 |
0.395 |
|
| 2008 |
Laird DW. Closing the gap on autosomal dominant connexin-26 and connexin-43 mutants linked to human disease. The Journal of Biological Chemistry. 283: 2997-3001. PMID 18089569 DOI: 10.1074/Jbc.R700041200 |
0.368 |
|
| 2007 |
Penuela S, Bhalla R, Gong XQ, Cowan KN, Celetti SJ, Cowan BJ, Bai D, Shao Q, Laird DW. Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. Journal of Cell Science. 120: 3772-83. PMID 17925379 DOI: 10.1242/Jcs.009514 |
0.488 |
|
| 2007 |
Langlois S, Maher AC, Manias JL, Shao Q, Kidder GM, Laird DW. Connexin levels regulate keratinocyte differentiation in the epidermis. The Journal of Biological Chemistry. 282: 30171-80. PMID 17693411 DOI: 10.1074/Jbc.M703623200 |
0.414 |
|
| 2007 |
McLachlan E, Shao Q, Laird DW. Connexins and gap junctions in mammary gland development and breast cancer progression. The Journal of Membrane Biology. 218: 107-21. PMID 17661126 DOI: 10.1007/S00232-007-9052-X |
0.355 |
|
| 2007 |
Thomas T, Shao Q, Laird DW. Differentiation of organotypic epidermis in the presence of skin disease-linked dominant-negative Cx26 mutants and knockdown Cx26. The Journal of Membrane Biology. 217: 93-104. PMID 17638039 DOI: 10.1007/S00232-007-9036-X |
0.414 |
|
| 2007 |
Gong XQ, Shao Q, Langlois S, Bai D, Laird DW. Differential potency of dominant negative connexin43 mutants in oculodentodigital dysplasia. The Journal of Biological Chemistry. 282: 19190-202. PMID 17420259 DOI: 10.1074/Jbc.M609653200 |
0.396 |
|
| 2006 |
McLachlan E, Shao Q, Wang HL, Langlois S, Laird DW. Connexins act as tumor suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis. Cancer Research. 66: 9886-94. PMID 17047050 DOI: 10.1158/0008-5472.Can-05-4302 |
0.426 |
|
| 2006 |
Gong XQ, Shao Q, Lounsbury CS, Bai D, Laird DW. Functional characterization of a GJA1 frameshift mutation causing oculodentodigital dysplasia and palmoplantar keratoderma. The Journal of Biological Chemistry. 281: 31801-11. PMID 16891658 DOI: 10.1074/Jbc.M605961200 |
0.423 |
|
| 2006 |
Kalra J, Shao Q, Qin H, Thomas T, Alaoui-Jamali MA, Laird DW. Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism. Carcinogenesis. 27: 2528-37. PMID 16777986 DOI: 10.1093/Carcin/Bgl110 |
0.487 |
|
| 2006 |
Hernandez M, Shao Q, Yang XJ, Luh SP, Kandouz M, Batist G, Laird DW, Alaoui-Jamali MA. A histone deacetylation-dependent mechanism for transcriptional repression of the gap junction gene cx43 in prostate cancer cells. The Prostate. 66: 1151-61. PMID 16652385 DOI: 10.1002/Pros.20451 |
0.303 |
|
| 2006 |
Laird DW. Life cycle of connexins in health and disease. The Biochemical Journal. 394: 527-43. PMID 16492141 DOI: 10.1042/Bj20051922 |
0.463 |
|
| 2005 |
McLachlan E, Manias JL, Gong XQ, Lounsbury CS, Shao Q, Bernier SM, Bai D, Laird DW. Functional characterization of oculodentodigital dysplasia-associated Cx43 mutants. Cell Communication & Adhesion. 12: 279-92. PMID 16531323 DOI: 10.1080/15419060500514143 |
0.455 |
|
| 2005 |
Maher AC, Thomas T, Riley JL, Veitch G, Shao Q, Laird DW. Rat epidermal keratinocytes as an organotypic model for examining the role of Cx43 and Cx26 in skin differentiation. Cell Communication & Adhesion. 12: 219-30. PMID 16531317 DOI: 10.1080/15419060500511818 |
0.412 |
|
| 2005 |
Thomas T, Jordan K, Simek J, Shao Q, Jedeszko C, Walton P, Laird DW. Mechanisms of Cx43 and Cx26 transport to the plasma membrane and gap junction regeneration. Journal of Cell Science. 118: 4451-62. PMID 16159960 DOI: 10.1242/Jcs.02569 |
0.751 |
|
| 2005 |
Flenniken AM, Osborne LR, Anderson N, Ciliberti N, Fleming C, Gittens JE, Gong XQ, Kelsey LB, Lounsbury C, Moreno L, Nieman BJ, Peterson K, Qu D, Roscoe W, Shao Q, ... ... Laird DW, et al. A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (Cambridge, England). 132: 4375-86. PMID 16155213 DOI: 10.1242/Dev.02011 |
0.375 |
|
| 2005 |
Pollmann MA, Shao Q, Laird DW, Sandig M. Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture. Breast Cancer Research : Bcr. 7: R522-34. PMID 15987459 DOI: 10.1186/Bcr1042 |
0.363 |
|
| 2005 |
Laird DW. Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation. Biochimica Et Biophysica Acta. 1711: 172-82. PMID 15955302 DOI: 10.1016/J.Bbamem.2004.09.009 |
0.421 |
|
| 2005 |
Shao Q, Wang H, McLachlan E, Veitch GI, Laird DW. Down-regulation of Cx43 by retroviral delivery of small interfering RNA promotes an aggressive breast cancer cell phenotype. Cancer Research. 65: 2705-11. PMID 15805269 DOI: 10.1158/0008-5472.Can-04-2367 |
0.427 |
|
| 2005 |
Roscoe W, Veitch GI, Gong XQ, Pellegrino E, Bai D, McLachlan E, Shao Q, Kidder GM, Laird DW. Oculodentodigital dysplasia-causing connexin43 mutants are non-functional and exhibit dominant effects on wild-type connexin43. The Journal of Biological Chemistry. 280: 11458-66. PMID 15644317 DOI: 10.1074/Jbc.M409564200 |
0.518 |
|
| 2005 |
Laird DW. 2005 International Gap Junction Conference Overview Cell Communication & Adhesion. 12: 73-84. DOI: 10.1080/15419060500440315 |
0.344 |
|
| 2004 |
Veitch GI, Gittens JE, Shao Q, Laird DW, Kidder GM. Selective assembly of connexin37 into heterocellular gap junctions at the oocyte/granulosa cell interface. Journal of Cell Science. 117: 2699-707. PMID 15138288 DOI: 10.1242/Jcs.01124 |
0.5 |
|
| 2004 |
Thomas T, Telford D, Laird DW. Functional domain mapping and selective trans-dominant effects exhibited by Cx26 disease-causing mutations. The Journal of Biological Chemistry. 279: 19157-68. PMID 14978038 DOI: 10.1074/Jbc.M314117200 |
0.434 |
|
| 2003 |
Qin H, Shao Q, Thomas T, Kalra J, Alaoui-Jamali MA, Laird DW. Connexin26 regulates the expression of angiogenesis-related genes in human breast tumor cells by both GJIC-dependent and -independent mechanisms. Cell Communication & Adhesion. 10: 387-93. PMID 14681046 DOI: 10.1080/Cac.10.4-6.387.393 |
0.442 |
|
| 2003 |
Thomas T, Aasen T, Hodgins M, Laird DW. Transport and function of cx26 mutants involved in skin and deafness disorders. Cell Communication & Adhesion. 10: 353-8. PMID 14681041 DOI: 10.1080/Cac.10.4-6.353.358 |
0.53 |
|
| 2003 |
Qin H, Shao Q, Igdoura SA, Alaoui-Jamali MA, Laird DW. Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells. The Journal of Biological Chemistry. 278: 30005-14. PMID 12767974 DOI: 10.1074/Jbc.M300614200 |
0.492 |
|
| 2003 |
Qin H, Shao Q, Belliveau DJ, Laird DW. Aggregated DsRed-tagged Cx43 and over-expressed Cx43 are targeted to lysosomes in human breast cancer cells. Cell Communication & Adhesion. 8: 433-9. PMID 12064631 DOI: 10.3109/15419060109080766 |
0.452 |
|
| 2002 |
Qin H, Shao Q, Curtis H, Galipeau J, Belliveau DJ, Wang T, Alaoui-Jamali MA, Laird DW. Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication. The Journal of Biological Chemistry. 277: 29132-8. PMID 12042301 DOI: 10.1074/Jbc.M200797200 |
0.389 |
|
| 2002 |
Gaietta G, Deerinck TJ, Adams SR, Bouwer J, Tour O, Laird DW, Sosinsky GE, Tsien RY, Ellisman MH. Multicolor and electron microscopic imaging of connexin trafficking. Science (New York, N.Y.). 296: 503-7. PMID 11964472 DOI: 10.1126/Science.1068793 |
0.355 |
|
| 2001 |
Thomas T, Jordan K, Laird DW. Role of cytoskeletal elements in the recruitment of Cx43-GFP and Cx26-YFP into gap junctions. Cell Communication & Adhesion. 8: 231-6. PMID 12064594 DOI: 10.3109/15419060109080729 |
0.756 |
|
| 2001 |
Laird DW, Jordan K, Shao Q. Expression and imaging of connexin-GFP chimeras in live mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 154: 135-42. PMID 11218645 DOI: 10.1385/1-59259-043-8:135 |
0.716 |
|
| 2001 |
Laird DW, Jordan K, Thomas T, Qin H, Fistouris P, Shao Q. Comparative analysis and application of fluorescent protein-tagged connexins. Microscopy Research and Technique. 52: 263-72. PMID 11180619 DOI: 10.1002/1097-0029(20010201)52:3<263::Aid-Jemt1012>3.0.Co;2-Q |
0.746 |
|
| 2001 |
Jordan K, Chodock R, Hand AR, Laird DW. The origin of annular junctions: a mechanism of gap junction internalization. Journal of Cell Science. 114: 763-73. PMID 11171382 |
0.756 |
|
| 2000 |
Mao AJ, Bechberger J, Lidington D, Galipeau J, Laird DW, Naus CCG. Neuronal differentiation and growth control of neuro-2a cells after retroviral gene delivery of connexin43 Journal of Biological Chemistry. 275: 34407-34414. PMID 10924505 DOI: 10.1074/Jbc.M003917200 |
0.436 |
|
| 2000 |
Zhang J, Gao JX, Salojin K, Shao Q, Grattan M, Meagher C, Laird DW, Delovitch TL. Regulation of fas ligand expression during activation-induced cell death in T cells by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase. The Journal of Experimental Medicine. 191: 1017-30. PMID 10727463 DOI: 10.1084/Jem.191.6.1017 |
0.334 |
|
| 2000 |
Bukauskas FF, Jordan K, Bukauskiene A, Bennett MV, Lampe PD, Laird DW, Verselis VK. Clustering of connexin 43-enhanced green fluorescent protein gap junction channels and functional coupling in living cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 2556-61. PMID 10706639 DOI: 10.1073/Pnas.050588497 |
0.734 |
|
| 2000 |
Laird DW, Saez JC. Post-transcri ptional events in the expression of gap junctions Advances in Molecular and Cell Biology. 30: 99-128. DOI: 10.1016/S1569-2558(00)30004-2 |
0.429 |
|
| 1999 |
Caruso JA, Laird DW, Batist G. Role of HSP90 in mediating cross-talk between the estrogen receptor and the Ah receptor signal transduction pathways. Biochemical Pharmacology. 58: 1395-403. PMID 10513983 DOI: 10.1016/S0006-2952(99)00225-7 |
0.326 |
|
| 1999 |
Cyr DG, Hermo L, Egenberger N, Mertineit C, Trasler JM, Laird DW. Cellular immunolocalization of occludin during embryonic and postnatal development of the mouse testis and epididymis. Endocrinology. 140: 3815-25. PMID 10433243 DOI: 10.1210/Endo.140.8.6903 |
0.384 |
|
| 1999 |
Jordan K, Solan JL, Dominguez M, Sia M, Hand A, Lampe PD, Laird DW. Trafficking, assembly, and function of a connexin43-green fluorescent protein chimera in live mammalian cells. Molecular Biology of the Cell. 10: 2033-50. PMID 10359613 DOI: 10.1091/Mbc.10.6.2033 |
0.763 |
|
| 1999 |
Sia MA, Woodward TL, Turner JD, Laird DW. Quiescent mammary epithelial cells have reduced connexin43 but maintain a high level of gap junction intercellular communication. Developmental Genetics. 24: 111-22. PMID 10079515 DOI: 10.1002/(Sici)1520-6408(1999)24:1/2<111::Aid-Dvg11>3.0.Co;2-P |
0.475 |
|
| 1997 |
Xie HQ, Laird DW, Chang TH, Hu VW. A mitosis-specific phosphorylation of the gap junction protein connexin43 in human vascular cells: Biochemical characterization and localization Journal of Cell Biology. 137: 203-210. PMID 9105048 DOI: 10.1083/jcb.137.1.203 |
0.334 |
|
| 1997 |
Feldman PA, Kim J, Laird DW. Loss of gap junction plaques and inhibition of intercellular communication in ilimaquinone-treated BICR-M1Rk and NRK cells. The Journal of Membrane Biology. 155: 275-87. PMID 9050451 DOI: 10.1007/s002329900180 |
0.363 |
|
| 1996 |
Laird DW. The life cycle of a connexin: gap junction formation, removal, and degradation. Journal of Bioenergetics and Biomembranes. 28: 311-8. PMID 8844328 DOI: 10.1007/BF02110107 |
0.394 |
|
| 1996 |
Cyr DG, Hermo L, Laird DW. Immunocytochemical localization and regulation of connexin43 in the adult rat epididymis. Endocrinology. 137: 1474-84. PMID 8625926 DOI: 10.1210/Endo.137.4.8625926 |
0.444 |
|
| 1996 |
Laird DW, Castillo M, Kasprzak L. Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells. The Journal of Cell Biology. 131: 1193-203. PMID 8522583 DOI: 10.1083/JCB.131.5.1193 |
0.378 |
|
| 1992 |
Laird DW, Yancey SB, Bugga L, Revel JP. Connexin expression and gap junction communication compartments in the developing mouse limb. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 195: 153-61. PMID 1338686 DOI: 10.1002/aja.1001950302 |
0.369 |
|
| 1992 |
Meyer RA, Laird DW, Revel JP, Johnson RG. Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies. The Journal of Cell Biology. 119: 179-89. PMID 1326565 |
0.323 |
|
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