Elizabeth M. Nolan - Publications

Affiliations: 
Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
metalloproteins
Website:
http://web.mit.edu/chemistry/www/faculty/nolan.html

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cunden LS, Nolan EM. Preparation of the Oxidized and Reduced Forms of Psoriasin (S100A7). Methods in Molecular Biology (Clifton, N.J.). 1929: 379-395. PMID 30710286 DOI: 10.1007/978-1-4939-9030-6_24  0.48
2018 Richardson CER, Nolan EM, Shoulders MD, Lippard SJ. A sensitive, non-radioactive assay for Zn(II) uptake into metazoan cells. Biochemistry. PMID 30381945 DOI: 10.1021/acs.biochem.8b01043  1
2018 Stephan JR, Yu F, Costello RM, Bleier BS, Nolan EM. Oxidative Post-Translational Modifications Accelerate Proteolytic Degradation of Calprotectin. Journal of the American Chemical Society. PMID 30380834 DOI: 10.1021/jacs.8b06354  0.56
2018 Cunden LS, Nolan EM. Bioinorganic Explorations of Zn(II) Sequestration by Human S100 Host-Defense Proteins. Biochemistry. PMID 29381858 DOI: 10.1021/acs.biochem.7b01305  0.48
2018 Richardson CER, Cunden LS, Butty VL, Nolan EM, Lippard SJ, Shoulders MD. A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency. Journal of the American Chemical Society. PMID 29334734 DOI: 10.1021/jacs.7b12897  1
2017 Johnstone TC, Nolan EM. Determination of the Molecular Structures of Ferric Enterobactin and Ferric Enantioenterobactin using Racemic Crystallography. Journal of the American Chemical Society. PMID 28956921 DOI: 10.1021/jacs.7b09375  0.8
2016 Nakashige TG, Stephan JR, Cunden LS, Brophy MB, Wommack AJ, Keegan BC, Shearer JM, Nolan EM. The Hexahistidine Motif of Host-Defense Protein Human Calprotectin Contributes to Zinc Withholding and Its Functional Versatility. Journal of the American Chemical Society. PMID 27541598 DOI: 10.1021/jacs.6b06845  0.56
2016 Stephan JR, Nolan EM. Calcium-induced Tetramerization and Zinc Chelation Shield Human Calprotectin from Degradation by Host and Bacterial Extracellular Proteases. Chemical Science (Royal Society of Chemistry : 2010). 7: 1962-1975. PMID 26925211 DOI: 10.1039/C5SC03287C  0.56
2016 Cunden LS, Gaillard A, Nolan EM. Calcium Ions Tune the Zinc-Sequestering Properties and Antimicrobial Activity of Human S100A12. Chemical Science (Royal Society of Chemistry : 2010). 7: 1338-1348. PMID 26913170 DOI: 10.1039/C5SC03655K  0.48
2015 Madsen JL, Johnstone TC, Nolan EM. Chemical Synthesis of Staphyloferrin B Affords Insight into the Molecular Structure, Iron Chelation, and Biological Activity of a Polycarboxylate Siderophore Deployed by the Human Pathogen Staphylococcus aureus. Journal of the American Chemical Society. PMID 26030732 DOI: 10.1021/jacs.5b04557  1
2015 Zheng T, Nolan EM. Evaluation of (acyloxy)alkyl ester linkers for antibiotic release from siderophore-antibiotic conjugates. Bioorganic & Medicinal Chemistry Letters. PMID 25794938 DOI: 10.1016/j.bmcl.2015.02.034  1
2015 Johnstone TC, Nolan EM. Beyond iron: non-classical biological functions of bacterial siderophores. Dalton Transactions (Cambridge, England : 2003). 44: 6320-39. PMID 25764171 DOI: 10.1039/c4dt03559c  1
2015 Chileveru HR, Lim SA, Chairatana P, Wommack AJ, Chiang IL, Nolan EM. Visualizing attack of Escherichia coli by the antimicrobial peptide human defensin 5. Biochemistry. 54: 1767-77. PMID 25664683 DOI: 10.1021/bi501483q  1
2015 Gagnon DM, Brophy MB, Bowman SE, Stich TA, Drennan CL, Britt RD, Nolan EM. Manganese binding properties of human calprotectin under conditions of high and low calcium: X-ray crystallographic and advanced electron paramagnetic resonance spectroscopic analysis. Journal of the American Chemical Society. 137: 3004-16. PMID 25597447 DOI: 10.1021/ja512204s  1
2015 Brophy MB, Nolan EM. Manganese and microbial pathogenesis: sequestration by the Mammalian immune system and utilization by microorganisms. Acs Chemical Biology. 10: 641-51. PMID 25594606 DOI: 10.1021/cb500792b  1
2015 Woods SE, Leonard MR, Hayden JA, Brophy MB, Bernert KR, Lavoie B, Muthupalani S, Whary MT, Mawe GM, Nolan EM, Carey MC, Fox JG. Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous "black" pigment gallstone formation in germfree Swiss Webster mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G335-49. PMID 25477375 DOI: 10.1152/ajpgi.00314.2014  1
2015 Chairatana P, Zheng T, Nolan EM. Targeting virulence: salmochelin modification tunes the antibacterial activity spectrum of β-lactams for pathogen-selective killing of Escherichia coli Chemical Science. 6: 4458-4471. DOI: 10.1039/c5sc00962f  1
2014 Moser S, Chileveru HR, Tomaras J, Nolan EM. A bacterial mutant library as a tool to study the attack of a defensin peptide. Chembiochem : a European Journal of Chemical Biology. 15: 2684-8. PMID 25430675 DOI: 10.1002/cbic.201402354  1
2014 Wommack AJ, Ziarek JJ, Tomaras J, Chileveru HR, Zhang Y, Wagner G, Nolan EM. Discovery and characterization of a disulfide-locked C(2)-symmetric defensin peptide. Journal of the American Chemical Society. 136: 13494-7. PMID 25181039 DOI: 10.1021/ja505957w  1
2014 Chairatana P, Nolan EM. Molecular basis for self-assembly of a human host-defense peptide that entraps bacterial pathogens. Journal of the American Chemical Society. 136: 13267-76. PMID 25158166 DOI: 10.1021/ja5057906  1
2014 Zheng T, Nolan EM. Enterobactin-mediated delivery of β-lactam antibiotics enhances antibacterial activity against pathogenic Escherichia coli. Journal of the American Chemical Society. 136: 9677-91. PMID 24927110 DOI: 10.1021/ja503911p  1
2014 Nolan EM, Shionoya M. Editorial overview: bioinorganic chemistry: recent advances in bioinorganic chemistry. Current Opinion in Chemical Biology. 19: vii-ix. PMID 24731720 DOI: 10.1016/j.cbpa.2014.03.016  1
2013 Brophy MB, Nakashige TG, Gaillard A, Nolan EM. Contributions of the S100A9 C-terminal tail to high-affinity Mn(II) chelation by the host-defense protein human calprotectin. Journal of the American Chemical Society. 135: 17804-17. PMID 24245608 DOI: 10.1021/ja407147d  1
2013 Zhang Y, Cougnon FB, Wanniarachchi YA, Hayden JA, Nolan EM. Reduction of human defensin 5 affords a high-affinity zinc-chelating peptide. Acs Chemical Biology. 8: 1907-11. PMID 23841778 DOI: 10.1021/cb400340k  1
2013 Hayden JA, Brophy MB, Cunden LS, Nolan EM. High-affinity manganese coordination by human calprotectin is calcium-dependent and requires the histidine-rich site formed at the dimer interface. Journal of the American Chemical Society. 135: 775-87. PMID 23276281 DOI: 10.1021/ja3096416  1
2012 Wommack AJ, Robson SA, Wanniarachchi YA, Wan A, Turner CJ, Wagner G, Nolan EM. NMR solution structure and condition-dependent oligomerization of the antimicrobial peptide human defensin 5. Biochemistry. 51: 9624-37. PMID 23163963 DOI: 10.1021/bi301255u  1
2012 Zheng T, Bullock JL, Nolan EM. Siderophore-mediated cargo delivery to the cytoplasm of Escherichia coli and Pseudomonas aeruginosa: syntheses of monofunctionalized enterobactin scaffolds and evaluation of enterobactin-cargo conjugate uptake. Journal of the American Chemical Society. 134: 18388-400. PMID 23098193 DOI: 10.1021/ja3077268  1
2012 Brophy MB, Hayden JA, Nolan EM. Calcium ion gradients modulate the zinc affinity and antibacterial activity of human calprotectin. Journal of the American Chemical Society. 134: 18089-100. PMID 23082970 DOI: 10.1021/ja307974e  1
2012 Zheng T, Nolan EM. Siderophore-based detection of Fe(III) and microbial pathogens. Metallomics : Integrated Biometal Science. 4: 866-80. PMID 22854844 DOI: 10.1039/c2mt20082a  1
2011 Wanniarachchi YA, Kaczmarek P, Wan A, Nolan EM. Human defensin 5 disulfide array mutants: disulfide bond deletion attenuates antibacterial activity against Staphylococcus aureus. Biochemistry. 50: 8005-17. PMID 21861459 DOI: 10.1021/bi201043j  1
2011 Nolan EM. Let's Visualize Biology: Chemistry and Cellular Imaging Letters to a Young Chemist. 119-136. DOI: 10.1002/9781118007099.ch8  1
2009 Strieker M, Nolan EM, Walsh CT, Marahiel MA. Stereospecific synthesis of threo- and erythro-beta-hydroxyglutamic acid during kutzneride biosynthesis. Journal of the American Chemical Society. 131: 13523-30. PMID 19722489 DOI: 10.1021/ja9054417  1
2009 Altmann KH, Buchner J, Kessler H, Diederich F, Kräutler B, Lippard S, Liskamp R, Müller K, Nolan EM, Samori B, Schneider G, Schreiber SL, Schwalbe H, Toniolo C, van Boeckel CA, et al. The state of the art of chemical biology. Chembiochem : a European Journal of Chemical Biology. 10: 16-29. PMID 19115274 DOI: 10.1002/cbic.200800758  1
2009 Nolan EM, Walsh CT. How nature morphs peptide scaffolds into antibiotics. Chembiochem : a European Journal of Chemical Biology. 10: 34-53. PMID 19058272 DOI: 10.1002/cbic.200800438  1
2009 Nolan EM, Lippard SJ. Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry. Accounts of Chemical Research. 42: 193-203. PMID 18989940 DOI: 10.1021/ar8001409  1
2008 Tomat E, Nolan EM, Jaworski J, Lippard SJ. Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells. Journal of the American Chemical Society. 130: 15776-7. PMID 18973293 DOI: 10.1021/ja806634e  1
2008 Nolan EM, Walsh CT. Investigations of the MceIJ-catalyzed posttranslational modification of the microcin E492 C-terminus: linkage of ribosomal and nonribosomal peptides to form "trojan horse" antibiotics. Biochemistry. 47: 9289-99. PMID 18690711 DOI: 10.1021/bi800826j  1
2008 Nolan EM, Lippard SJ. Tools and tactics for the optical detection of mercuric ion. Chemical Reviews. 108: 3443-80. PMID 18652512 DOI: 10.1021/cr068000q  1
2008 Walsh CT, Nolan EM. Morphing peptide backbones into heterocycles. Proceedings of the National Academy of Sciences of the United States of America. 105: 5655-6. PMID 18398003 DOI: 10.1073/pnas.0802300105  1
2008 Roush RF, Nolan EM, Löhr F, Walsh CT. Maturation of an Escherichia coli ribosomal peptide antibiotic by ATP-consuming N-P bond formation in microcin C7. Journal of the American Chemical Society. 130: 3603-9. PMID 18290647 DOI: 10.1021/ja7101949  1
2008 Roush RF, Nolan EM, Löhr F, Walsh CT. Maturation of an Escherichia coli ribosomal peptide antibiotic by ATP-consuming N-P bond formation in microcin C7 (Journal of the American Chemical Society (2008) 130, (3603-3609)) Journal of the American Chemical Society. 130: 6055. DOI: 10.1021/ja802086j  1
2007 Nolan EM, Fischbach MA, Koglin A, Walsh CT. Biosynthetic tailoring of microcin E492m: post-translational modification affords an antibacterial siderophore-peptide conjugate. Journal of the American Chemical Society. 129: 14336-47. PMID 17973380 DOI: 10.1021/ja074650f  1
2007 Neidig ML, Brown CD, Light KM, Fujimori DG, Nolan EM, Price JC, Barr EW, Bollinger JM, Krebs C, Walsh CT, Solomon EI. CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases. Journal of the American Chemical Society. 129: 14224-31. PMID 17967013 DOI: 10.1021/ja074557r  1
2007 Nolan EM, Lippard SJ. Turn-on and ratiometric mercury sensing in water with a red-emitting probe. Journal of the American Chemical Society. 129: 5910-8. PMID 17429971 DOI: 10.1021/ja068879r  1
2006 Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ. Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization. Journal of the American Chemical Society. 128: 15517-28. PMID 17132019 DOI: 10.1021/ja065759a  1
2006 Nolan EM, Jaworski J, Racine ME, Sheng M, Lippard SJ. Midrange affinity fluorescent Zn(II) sensors of the Zinpyr family: syntheses, characterization, and biological imaging applications. Inorganic Chemistry. 45: 9748-57. PMID 17112271 DOI: 10.1021/ic061137e  1
2006 Nolan EM, Racine ME, Lippard SJ. Selective Hg(II) detection in aqueous solution with thiol derivatized fluoresceins. Inorganic Chemistry. 45: 2742-9. PMID 16529499 DOI: 10.1021/ic052083w  1
2005 Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ. QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). Journal of the American Chemical Society. 127: 16812-23. PMID 16316228 DOI: 10.1021/ja052184t  1
2005 Nolan EM, Lippard SJ. MS4, a seminaphthofluorescein-based chemosensor for the ratiometric detection of Hg(II) Journal of Materials Chemistry. 15: 2778-2783. DOI: 10.1039/b501615k  1
2004 Nolan EM, Lippard SJ. The zinspy family of fluorescent zinc sensors: syntheses and spectroscopic investigations. Inorganic Chemistry. 43: 8310-7. PMID 15606177 DOI: 10.1021/ic048778z  1
2004 Chang CJ, Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ. ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. Inorganic Chemistry. 43: 6774-9. PMID 15476377 DOI: 10.1021/ic049293d  1
2004 Chang CJ, Nolan EM, Jaworski J, Burdette SC, Sheng M, Lippard SJ. Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zinc. Chemistry & Biology. 11: 203-10. PMID 15123282 DOI: 10.1016/j.chembiol.2004.01.017  1
2004 Nolan EM, Burdette SC, Harvey JH, Hilderbrand SA, Lippard SJ. Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. Inorganic Chemistry. 43: 2624-35. PMID 15074981 DOI: 10.1021/ic035158+  1
2004 Chang CJ, Jaworski J, Nolan EM, Sheng M, Lippard SJ. A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc. Proceedings of the National Academy of Sciences of the United States of America. 101: 1129-34. PMID 14734801 DOI: 10.1073/pnas.0308079100  1
2003 Nolan EM, Lippard SJ. A "turn-on" fluorescent sensor for the selective detection of mercuric ion in aqueous media. Journal of the American Chemical Society. 125: 14270-1. PMID 14624563 DOI: 10.1021/ja037995g  1
2002 Nolan EM, Linck RG. Through-space charge and dipolar effects in substituted ethanes and 1,1,1-trifluoroethanes Journal of Physical Chemistry A. 106: 533-543. DOI: 10.1021/jp012969v  1
2001 Nolan EM, Linck RG. An exploration of long range electronic effects in substituted alkanes Journal of Physical Chemistry A. 105: 7297-7307. DOI: 10.1021/jp010833r  1
2000 Nolan EM, Linck RG. Charge variations in substituted alkanes: Evidence for a through-space effect Journal of the American Chemical Society. 122: 11497-11506. DOI: 10.1021/ja0026511  1
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