| Year |
Citation |
Score |
| 2021 |
Gearty SV, Dündar F, Zumbo P, Espinosa-Carrasco G, Shakiba M, Sanchez-Rivera FJ, Socci ND, Trivedi P, Lowe SW, Lauer P, Mohibullah N, Viale A, DiLorenzo TP, Betel D, Schietinger A. An autoimmune stem-like CD8 T cell population drives type 1 diabetes. Nature. PMID 34847567 DOI: 10.1038/s41586-021-04248-x |
0.571 |
|
| 2021 |
Amdare N, Purcell AW, DiLorenzo TP. Non-contiguous T cell epitopes in autoimmune diabetes: From mice to men and back again. The Journal of Biological Chemistry. 100827. PMID 34044020 DOI: 10.1016/j.jbc.2021.100827 |
0.668 |
|
| 2020 |
James EA, Mallone R, Kent SC, DiLorenzo TP. T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal. Diabetes. 69: 1311-1335. PMID 32561620 DOI: 10.2337/Dbi19-0022 |
0.661 |
|
| 2019 |
Schloss J, Ali R, Babad J, Guerrero-Ros I, Pongsachai J, He LZ, Keler T, DiLorenzo TP. Development and Characterization of a Preclinical Model for the Evaluation of CD205-Mediated Antigen Delivery Therapeutics in Type 1 Diabetes. Immunohorizons. 3: 236-253. PMID 31356169 DOI: 10.4049/immunohorizons.1900014 |
0.806 |
|
| 2019 |
Purcell AW, Sechi S, DiLorenzo TP. The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes. Diabetes. 68: 879-886. PMID 31010879 DOI: 10.2337/Dbi18-0066 |
0.556 |
|
| 2018 |
Schloss J, Ali R, Racine JJ, Chapman HD, Serreze DV, DiLorenzo TP. HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression. Journal of Immunology (Baltimore, Md. : 1950). PMID 29632144 DOI: 10.4049/Jimmunol.1701652 |
0.626 |
|
| 2018 |
Racine JJ, Stewart I, Ratiu J, Christianson G, Lowell E, Helm K, Allocco J, Maser RS, Chen YG, Lutz CM, Roopenian D, Schloss J, DiLorenzo TP, Serreze DV. Improved Murine-MHC-Deficient HLA-Transgenic NOD-Mouse Models for Type 1 Diabetes Therapy Development. Diabetes. PMID 29472249 DOI: 10.2337/Db17-1467 |
0.534 |
|
| 2016 |
Serreze DV, Niens M, Kulik J, DiLorenzo TP. Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans. Methods in Molecular Biology (Clifton, N.J.). 1438: 137-51. PMID 27150089 DOI: 10.1007/978-1-4939-3661-8_9 |
0.665 |
|
| 2016 |
Ali R, Babad J, Follenzi A, Gebe JA, Brehm MA, Nepom GT, Shultz LD, Greiner DL, DiLorenzo TP. Genetically Modified Human CD4(+) T Cells Can Be Evaluated In Vivo Without Lethal Graft Versus Host Disease. Immunology. PMID 27124592 DOI: 10.1111/Imm.12613 |
0.822 |
|
| 2016 |
Babad J, Ali R, Schloss J, DiLorenzo TP. An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients. Journal of Diabetes Research. 2016: 7959060. PMID 26824049 DOI: 10.1155/2016/7959060 |
0.814 |
|
| 2016 |
Sidney J, Schloss J, Moore C, Lindvall M, Wriston A, Hunt DF, Shabanowitz J, DiLorenzo TP, Sette A. Characterization of the peptide binding specificity of the HLA class I alleles B*38:01 and B*39:06. Immunogenetics. PMID 26754738 DOI: 10.1007/S00251-015-0898-2 |
0.445 |
|
| 2016 |
Babad J, Ali R, Schloss J, DiLorenzo TP. An HLA-transgenic mouse model of type 1 diabetes that incorporates the reduced but not abolished thymic insulin expression seen in patients Journal of Diabetes Research. 2016. DOI: 10.1155/2016/7959060 |
0.388 |
|
| 2015 |
Katakowski JA, Mukherjee G, Wilner SE, Maier KE, Harrison MT, DiLorenzo TP, Levy M, Palliser D. Delivery of siRNAs to Dendritic Cells Using DEC205-Targeted Lipid Nanoparticles to Inhibit Immune Responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26412590 DOI: 10.1038/Mt.2015.175 |
0.44 |
|
| 2015 |
Mukherjee G, Chaparro RJ, Schloss J, Smith C, Bando CD, DiLorenzo TP. Glucagon-reactive islet-infiltrating CD8 T cells in NOD mice. Immunology. 144: 631-40. PMID 25333865 DOI: 10.1111/Imm.12415 |
0.716 |
|
| 2015 |
Babad J, Mukherjee G, Follenzi A, Ali R, Roep BO, Shultz LD, Santamaria P, Yang OO, Goldstein H, Greiner DL, DiLorenzo TP. Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice. Clinical and Experimental Immunology. 179: 398-413. PMID 25302633 DOI: 10.1111/Cei.12465 |
0.844 |
|
| 2014 |
Lamont D, Mukherjee G, Kumar PR, Samanta D, McPhee CG, Kay TW, Almo SC, DiLorenzo TP, Serreze DV. Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 193: 2135-46. PMID 25063871 DOI: 10.4049/Jimmunol.1400997 |
0.652 |
|
| 2013 |
Mukherjee G, Geliebter A, Babad J, Santamaria P, Serreze DV, Freeman GJ, Tarbell KV, Sharpe A, DiLorenzo TP. DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8⁺ T cells independently of PD-1 and PD-L1. International Immunology. 25: 651-60. PMID 24021877 DOI: 10.1093/Intimm/Dxt031 |
0.819 |
|
| 2012 |
Antal Z, Baker JC, Smith C, Jarchum I, Babad J, Mukherjee G, Yang Y, Sidney J, Sette A, Santamaria P, DiLorenzo TP. Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes. Journal of Immunology (Baltimore, Md. : 1950). 188: 5766-75. PMID 22539795 DOI: 10.4049/Jimmunol.1102930 |
0.811 |
|
| 2011 |
DiLorenzo TP. Multiple antigens versus single major antigen in type 1 diabetes: arguing for multiple antigens. Diabetes/Metabolism Research and Reviews. 27: 778-83. PMID 22069259 DOI: 10.1002/Dmrr.1251 |
0.583 |
|
| 2011 |
Samanta D, Mukherjee G, Ramagopal UA, Chaparro RJ, Nathenson SG, DiLorenzo TP, Almo SC. Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 13682-7. PMID 21825122 DOI: 10.1073/Pnas.1110971108 |
0.663 |
|
| 2010 |
Babad J, Geliebter A, DiLorenzo TP. T-cell autoantigens in the non-obese diabetic mouse model of autoimmune diabetes. Immunology. 131: 459-65. PMID 21039471 DOI: 10.1111/J.1365-2567.2010.03362.X |
0.818 |
|
| 2010 |
Chaparro RJ, Dilorenzo TP. An update on the use of NOD mice to study autoimmune (Type 1) diabetes. Expert Review of Clinical Immunology. 6: 939-55. PMID 20979558 DOI: 10.1586/Eci.10.68 |
0.477 |
|
| 2010 |
Mukherjee G, Dilorenzo TP. The immunotherapeutic potential of dendritic cells in type 1 diabetes. Clinical and Experimental Immunology. 161: 197-207. PMID 20491789 DOI: 10.1111/J.1365-2249.2010.04157.X |
0.637 |
|
| 2010 |
Brims DR, Qian J, Jarchum I, Mikesh L, Palmieri E, Ramagopal UA, Malashkevich VN, Chaparro RJ, Lund T, Hattori M, Shabanowitz J, Hunt DF, Nathenson SG, Almo SC, Dilorenzo TP. Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect. International Immunology. 22: 191-203. PMID 20093428 DOI: 10.1093/Intimm/Dxp127 |
0.806 |
|
| 2010 |
Serreze DV, Niens M, Kulik J, Dilorenzo TP. Bridging mice to men: using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans. Methods in Molecular Biology (Clifton, N.J.). 602: 119-34. PMID 20012396 DOI: 10.1007/978-1-60761-058-8_8 |
0.6 |
|
| 2010 |
Jarchum I, DiLorenzo TP. Ins2 deficiency augments spontaneous HLA-A*0201-restricted T cell responses to insulin. Journal of Immunology (Baltimore, Md. : 1950). 184: 658-65. PMID 19966211 DOI: 10.4049/Jimmunol.0903414 |
0.818 |
|
| 2009 |
Kojaoghlanian T, Joseph A, Follenzi A, Zheng JH, Leiser M, Fleischer N, Horwitz MS, DiLorenzo TP, Goldstein H. Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic beta-cells to correct diabetes in allogeneic mice. Gene Therapy. 16: 340-8. PMID 19112449 DOI: 10.1038/Gt.2008.172 |
0.415 |
|
| 2008 |
Antal Z, Jarchum I, DiLorenzo TP. HLA class I supertypes in type 1 diabetic children in an urban children's hospital. Annals of the New York Academy of Sciences. 1150: 86-9. PMID 19120273 DOI: 10.1196/Annals.1447.005 |
0.774 |
|
| 2008 |
Jarchum I, Takaki T, DiLorenzo TP. Efficient culture of CD8(+) T cells from the islets of NOD mice and their use for the study of autoreactive specificities. Journal of Immunological Methods. 339: 66-73. PMID 18782577 DOI: 10.1016/J.Jim.2008.08.007 |
0.799 |
|
| 2008 |
Chaparro RJ, Burton AR, Serreze DV, Vignali DA, DiLorenzo TP. Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells. Journal of Immunological Methods. 335: 106-15. PMID 18439618 DOI: 10.1016/J.Jim.2008.03.007 |
0.697 |
|
| 2008 |
Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP. Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 6374-9. PMID 18430797 DOI: 10.1073/Pnas.0802644105 |
0.83 |
|
| 2008 |
Jarchum I, Nichol L, Trucco M, Santamaria P, DiLorenzo TP. Identification of novel IGRP epitopes targeted in type 1 diabetes patients. Clinical Immunology (Orlando, Fla.). 127: 359-65. PMID 18358785 DOI: 10.1016/J.Clim.2008.01.015 |
0.812 |
|
| 2008 |
Joseph A, Zheng JH, Follenzi A, Dilorenzo T, Sango K, Hyman J, Chen K, Piechocka-Trocha A, Brander C, Hooijberg E, Vignali DA, Walker BD, Goldstein H. Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity. Journal of Virology. 82: 3078-89. PMID 18184707 DOI: 10.1128/Jvi.01812-07 |
0.373 |
|
| 2008 |
Chaparro R, Burton A, Serreze D, Vignali D, DiLorenzo T. Sa.67. Rapid Identification of MHC Class I-restricted Antigens Relevant to Autoimmune Diabetes Using Retrogenic T Cells Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.288 |
0.634 |
|
| 2007 |
Chattopadhyay K, Ramagopal UA, Mukhopadhaya A, Malashkevich VN, Dilorenzo TP, Brenowitz M, Nathenson SG, Almo SC. Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function. Proceedings of the National Academy of Sciences of the United States of America. 104: 19452-7. PMID 18040044 DOI: 10.1073/Pnas.0709264104 |
0.331 |
|
| 2007 |
Jarchum I, Baker JC, Yamada T, Takaki T, Marron MP, Serreze DV, DiLorenzo TP. In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice. Diabetes. 56: 2551-60. PMID 17620420 DOI: 10.2337/Db07-0332 |
0.846 |
|
| 2007 |
Serreze DV, Marron MP, Dilorenzo TP. "Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes. Annals of the New York Academy of Sciences. 1103: 103-11. PMID 17376821 DOI: 10.1196/Annals.1394.019 |
0.659 |
|
| 2007 |
Cao E, Zang X, Ramagopal UA, Mukhopadhaya A, Fedorov A, Fedorov E, Zencheck WD, Lary JW, Cole JL, Deng H, Xiao H, Dilorenzo TP, Allison JP, Nathenson SG, Almo SC. T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface. Immunity. 26: 311-21. PMID 17363302 DOI: 10.1016/J.Immuni.2007.01.016 |
0.442 |
|
| 2007 |
Forestier C, Takaki T, Molano A, Im JS, Baine I, Jerud ES, Illarionov P, Ndonye R, Howell AR, Santamaria P, Besra GS, Dilorenzo TP, Porcelli SA. Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator. Journal of Immunology (Baltimore, Md. : 1950). 178: 1415-25. PMID 17237389 DOI: 10.4049/Jimmunol.178.3.1415 |
0.445 |
|
| 2006 |
Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, Trucco M, DiLorenzo TP, Serreze DV. HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 176: 3257-65. PMID 16493087 DOI: 10.4049/Jimmunol.176.5.3257 |
0.712 |
|
| 2006 |
Roden MM, Brims DR, Fedorov AA, DiLorenzo TP, Almo SC, Nathenson SG. Structural analysis of H2-Db class I molecules containing two different allelic forms of the type 1 diabetes susceptibility factor beta-2 microglobulin: implications for the mechanism underlying variations in antigen presentation. Molecular Immunology. 43: 1370-8. PMID 16229893 DOI: 10.1016/J.Molimm.2005.08.005 |
0.459 |
|
| 2005 |
Han B, Serra P, Yamanouchi J, Amrani A, Elliott JF, Dickie P, Dilorenzo TP, Santamaria P. Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes. The Journal of Clinical Investigation. 115: 1879-87. PMID 15937548 DOI: 10.1172/Jci24219 |
0.701 |
|
| 2005 |
DiLorenzo TP, Serreze DV. The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice. Immunological Reviews. 204: 250-63. PMID 15790363 DOI: 10.1111/J.0105-2896.2005.00244.X |
0.681 |
|
| 2004 |
Lieberman SM, Takaki T, Han B, Santamaria P, Serreze DV, DiLorenzo TP. Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase. Journal of Immunology (Baltimore, Md. : 1950). 173: 6727-34. PMID 15557165 DOI: 10.4049/Jimmunol.173.11.6727 |
0.671 |
|
| 2004 |
Takaki T, Lieberman SM, Holl TM, Han B, Santamaria P, Serreze DV, DiLorenzo TP. Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4. Journal of Immunology (Baltimore, Md. : 1950). 173: 2530-41. PMID 15294969 DOI: 10.4049/Jimmunol.173.4.2530 |
0.645 |
|
| 2004 |
Serreze DV, Holl TM, Marron MP, Graser RT, Johnson EA, Choisy-Rossi C, Slattery RM, Lieberman SM, DiLorenzo TP. MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 172: 871-9. PMID 14707058 DOI: 10.4049/Jimmunol.172.2.871 |
0.657 |
|
| 2003 |
Lieberman SM, DiLorenzo TP. A comprehensive guide to antibody and T-cell responses in type 1 diabetes. Tissue Antigens. 62: 359-77. PMID 14617043 DOI: 10.1034/J.1399-0039.2003.00152.X |
0.626 |
|
| 2003 |
Lieberman SM, Evans AM, Han B, Takaki T, Vinnitskaya Y, Caldwell JA, Serreze DV, Shabanowitz J, Hunt DF, Nathenson SG, Santamaria P, DiLorenzo TP. Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. 100: 8384-8. PMID 12815107 DOI: 10.1073/Pnas.0932778100 |
0.691 |
|
| 2002 |
DiLorenzo TP, Lieberman SM, Takaki T, Honda S, Chapman HD, Santamaria P, Serreze DV, Nathenson SG. During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities. Clinical Immunology (Orlando, Fla.). 105: 332-41. PMID 12498815 DOI: 10.1006/Clim.2002.5298 |
0.691 |
|
| 2001 |
Zhang W, Honda S, Wang F, DiLorenzo TP, Kalergis AM, Ostrov DA, Nathenson SG. Immunobiological analysis of TCR single-chain transgenic mice reveals new possibilities for interaction between CDR3alpha and an antigenic peptide bound to MHC class I. Journal of Immunology (Baltimore, Md. : 1950). 167: 4396-404. PMID 11591764 DOI: 10.4049/Jimmunol.167.8.4396 |
0.464 |
|
| 2001 |
Honda S, Zhang W, Kalergis AM, DiLorenzo TP, Wang F, Nathenson SG. Hapten addition to an MHC class I-binding peptide causes substantial adjustments of the TCR structure of the responding CD8(+) T cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 4276-85. PMID 11591750 DOI: 10.4049/Jimmunol.167.8.4276 |
0.476 |
|
| 2001 |
Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S. Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool. Diabetes. 50: 1992-2000. PMID 11522664 DOI: 10.2337/Diabetes.50.9.1992 |
0.688 |
|
| 2000 |
Graser RT, DiLorenzo TP, Wang F, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV. Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions. Journal of Immunology (Baltimore, Md. : 1950). 164: 3913-8. PMID 10725754 DOI: 10.4049/Jimmunol.164.7.3913 |
0.66 |
|
| 1998 |
DiLorenzo TP, Graser RT, Ono T, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV. Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement. Proceedings of the National Academy of Sciences of the United States of America. 95: 12538-43. PMID 9770521 DOI: 10.1073/Pnas.95.21.12538 |
0.687 |
|
| 1998 |
Wang F, Ono T, Kalergis AM, Zhang W, DiLorenzo TP, Lim K, Nathenson SG. On defining the rules for interactions between the T cell receptor and its ligand: a critical role for a specific amino acid residue of the T cell receptor beta chain. Proceedings of the National Academy of Sciences of the United States of America. 95: 5217-22. PMID 9560256 DOI: 10.1073/Pnas.95.9.5217 |
0.447 |
|
| 1991 |
Reppucci AD, DiLorenzo TP, Abramson AL, Steinberg BM. In vitro modulation of human laryngeal papilloma cell differentiation by retinoic acid. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 105: 528-32. PMID 1662346 DOI: 10.1177/019459989110500404 |
0.345 |
|
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