Brad L. Pentelute - Publications

Affiliations: 
Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
characterization of chemically modified proteins with modern biophysical techniques such as single-molecule electrophysiology, EPR, protein X-ray crystallography, protein NMR, and biological mass spectrometry
Website:
http://chemistry.mit.edu/people/pentelute-bradley

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Simon MD, Maki Y, Vinogradov AA, Zhang C, Yu H, Lin YS, Kajihara Y, Pentelute BL. D-amino acid scan of two small proteins. Journal of the American Chemical Society. PMID 27494078 DOI: 10.1021/jacs.6b03765  0.8
2016 Zhang C, Welborn M, Zhu T, Yang NJ, Santos MS, Van Voorhis T, Pentelute BL. π-Clamp-mediated cysteine conjugation. Nature Chemistry. 8: 120-8. PMID 26791894 DOI: 10.1038/nchem.2413  1
2015 Vinogradova EV, Zhang C, Spokoyny AM, Pentelute BL, Buchwald SL. Organometallic palladium reagents for cysteine bioconjugation. Nature. 526: 687-91. PMID 26511579 DOI: 10.1038/nature15739  0.8
2015 Cohen DT, Zhang C, Pentelute BL, Buchwald SL. An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides. Journal of the American Chemical Society. 137: 9784-7. PMID 26225900 DOI: 10.1021/jacs.5b05447  0.8
2015 Rabideau AE, Liao X, Akçay G, Pentelute BL. Translocation of Non-Canonical Polypeptides into Cells Using Protective Antigen. Scientific Reports. 5: 11944. PMID 26178180 DOI: 10.1038/srep11944  1
2015 Bunker RD, Mandal K, Bashiri G, Chaston JJ, Pentelute BL, Lott JS, Kent SB, Baker EN. A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography. Proceedings of the National Academy of Sciences of the United States of America. 112: 4310-5. PMID 25831534 DOI: 10.1073/pnas.1422387112  0.96
2015 Jiang J, Pentelute BL, Collier RJ, Zhou ZH. Atomic structure of anthrax protective antigen pore elucidates toxin translocation. Nature. 521: 545-9. PMID 25778700 DOI: 10.1038/nature14247  1
2015 Akkaladevi N, Mukherjee S, Katayama H, Janowiak B, Patel D, Gogol EP, Pentelute BL, John Collier R, Fisher MT. Following Natures Lead: On the Construction of Membrane-Inserted Toxins in Lipid Bilayer Nanodiscs. The Journal of Membrane Biology. 248: 595-607. PMID 25578459 DOI: 10.1007/s00232-014-9768-3  1
2015 Vinogradov AA, Evans ED, Pentelute BL. Total synthesis and biochemical characterization of mirror image barnase Chemical Science. 6: 2997-3002. DOI: 10.1039/c4sc03877k  1
2015 Rabideau AE, Liao X, Pentelute BL. Delivery of mirror image polypeptides into cells Chemical Science. 6: 648-653. DOI: 10.1039/c4sc02078b  1
2015 Cohen DT, Zhang C, Pentelute BL, Buchwald SL. An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides Journal of the American Chemical Society. 137: 9784-9787. DOI: 10.1021/jacs.5b05447  1
2014 Liao X, Rabideau AE, Pentelute BL. Delivery of antibody mimics into mammalian cells via anthrax toxin protective antigen. Chembiochem : a European Journal of Chemical Biology. 15: 2458-66. PMID 25250705 DOI: 10.1002/cbic.201402290  1
2014 Zhang C, Dai P, Spokoyny AM, Pentelute BL. Enzyme-catalyzed macrocyclization of long unprotected peptides. Organic Letters. 16: 3652-5. PMID 25002256 DOI: 10.1021/ol501609y  1
2014 Policarpo RL, Kang H, Liao X, Rabideau AE, Simon MD, Pentelute BL. Flow-based enzymatic ligation by sortase A. Angewandte Chemie (International Ed. in English). 53: 9203-8. PMID 24989829 DOI: 10.1002/anie.201403582  0.6
2014 Mong SK, Vinogradov AA, Simon MD, Pentelute BL. Rapid total synthesis of DARPin pE59 and barnase. Chembiochem : a European Journal of Chemical Biology. 15: 721-33. PMID 24616257 DOI: 10.1002/cbic.201300797  0.6
2014 Simon MD, Heider PL, Adamo A, Vinogradov AA, Mong SK, Li X, Berger T, Policarpo RL, Zhang C, Zou Y, Liao X, Spokoyny AM, Jensen KF, Pentelute BL. Rapid flow-based peptide synthesis. Chembiochem : a European Journal of Chemical Biology. 15: 713-20. PMID 24616230 DOI: 10.1002/cbic.201300796  1
2014 Zou Y, Spokoyny AM, Zhang C, Simon MD, Yu H, Lin YS, Pentelute BL. Convergent diversity-oriented side-chain macrocyclization scan for unprotected polypeptides. Organic & Biomolecular Chemistry. 12: 566-73. PMID 24310320 DOI: 10.1039/c3ob42168f  0.8
2013 Zhang C, Spokoyny AM, Zou Y, Simon MD, Pentelute BL. Enzymatic "click" ligation: selective cysteine modification in polypeptides enabled by promiscuous glutathione S-transferase. Angewandte Chemie (International Ed. in English). 52: 14001-5. PMID 24222025 DOI: 10.1002/anie.201306430  0.8
2013 Naik S, Brock S, Akkaladevi N, Tally J, McGinn-Straub W, Zhang N, Gao P, Gogol EP, Pentelute BL, Collier RJ, Fisher MT. Monitoring the kinetics of the pH-driven transition of the anthrax toxin prepore to the pore by biolayer interferometry and surface plasmon resonance. Biochemistry. 52: 6335-47. PMID 23964683 DOI: 10.1021/bi400705n  1
2013 Spokoyny AM, Zou Y, Ling JJ, Yu H, Lin YS, Pentelute BL. A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling. Journal of the American Chemical Society. 135: 5946-9. PMID 23560559 DOI: 10.1021/ja400119t  1
2013 Gogol EP, Akkaladevi N, Szerszen L, Mukherjee S, Chollet-Hinton L, Katayama H, Pentelute BL, Collier RJ, Fisher MT. Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryo-electron microscopy. Protein Science : a Publication of the Protein Society. 22: 586-94. PMID 23494942 DOI: 10.1002/pro.2241  1
2013 Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, et al. Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science (New York, N.Y.). 339: 1216-9. PMID 23471411 DOI: 10.1126/science.1231097  1
2013 Akkaladevi N, Hinton-Chollet L, Katayama H, Mitchell J, Szerszen L, Mukherjee S, Gogol EP, Pentelute BL, Collier RJ, Fisher MT. Assembly of anthrax toxin pore: lethal-factor complexes into lipid nanodiscs. Protein Science : a Publication of the Protein Society. 22: 492-501. PMID 23389868 DOI: 10.1002/pro.2231  1
2012 Ling JJ, Policarpo RL, Rabideau AE, Liao X, Pentelute BL. Protein thioester synthesis enabled by sortase. Journal of the American Chemical Society. 134: 10749-52. PMID 22686546 DOI: 10.1021/ja302354v  1
2012 Kent S, Sohma Y, Liu S, Bang D, Pentelute B, Mandal K. Through the looking glass--a new world of proteins enabled by chemical synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 428-36. PMID 22674813 DOI: 10.1002/psc.2421  1
2012 Mandal K, Pentelute BL, Bang D, Gates ZP, Torbeev VY, Kent SB. Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology. Angewandte Chemie (International Ed. in English). 51: 1481-6. PMID 22213444 DOI: 10.1002/anie.201107846  1
2012 Sawaya MR, Pentelute BL, Kent SB, Yeates TO. Single-wavelength phasing strategy for quasi-racemic protein crystal diffraction data. Acta Crystallographica. Section D, Biological Crystallography. 68: 62-8. PMID 22194334 DOI: 10.1107/S0907444911049985  1
2012 Liu S, Pentelute BL, Kent SB. Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin. Angewandte Chemie (International Ed. in English). 51: 993-9. PMID 22180156 DOI: 10.1002/anie.201106060  1
2011 Fischer A, Holden MA, Pentelute BL, Collier RJ. Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers. Proceedings of the National Academy of Sciences of the United States of America. 108: 16577-81. PMID 21949363 DOI: 10.1073/pnas.1113074108  1
2011 Lee J, Kwon Y, Pentelute BL, Bang D. Use of model peptide reactions for the characterization of kinetically controlled ligation. Bioconjugate Chemistry. 22: 1645-9. PMID 21740060 DOI: 10.1021/bc2002242  1
2011 Pentelute BL, Sharma O, Collier RJ. Chemical dissection of protein translocation through the anthrax toxin pore. Angewandte Chemie (International Ed. in English). 50: 2294-6. PMID 21351339 DOI: 10.1002/anie.201006460  1
2010 Pentelute BL, Mandal K, Gates ZP, Sawaya MR, Yeates TO, Kent SB. Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography. Chemical Communications (Cambridge, England). 46: 8174-6. PMID 20877851 DOI: 10.1039/c0cc03148h  1
2010 Pentelute BL, Barker AP, Janowiak BE, Kent SB, Collier RJ. A semisynthesis platform for investigating structure-function relationships in the N-terminal domain of the anthrax Lethal Factor. Acs Chemical Biology. 5: 359-64. PMID 20180595 DOI: 10.1021/cb100003r  1
2009 Mandal K, Pentelute BL, Tereshko V, Thammavongsa V, Schneewind O, Kossiakoff AA, Kent SB. Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods. Protein Science : a Publication of the Protein Society. 18: 1146-54. PMID 19472324 DOI: 10.1002/pro.127  1
2009 Mandal K, Pentelute BL, Tereshko V, Kossiakoff AA, Kent SB. X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods. Journal of the American Chemical Society. 131: 1362-3. PMID 19133782 DOI: 10.1021/ja8077973  1
2008 Pentelute BL, Gates ZP, Tereshko V, Dashnau JL, Vanderkooi JM, Kossiakoff AA, Kent SB. X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers. Journal of the American Chemical Society. 130: 9695-701. PMID 18598029 DOI: 10.1021/ja8013538  1
2008 Pentelute BL, Gates ZP, Dashnau JL, Vanderkooi JM, Kent SB. Mirror image forms of snow flea antifreeze protein prepared by total chemical synthesis have identical antifreeze activities. Journal of the American Chemical Society. 130: 9702-7. PMID 18598026 DOI: 10.1021/ja801352j  1
2008 Sohma Y, Pentelute BL, Whittaker J, Hua QX, Whittaker LJ, Weiss MA, Kent SB. Comparative properties of insulin-like growth factor 1 (IGF-1) and [Gly7D-Ala]IGF-1 prepared by total chemical synthesis. Angewandte Chemie (International Ed. in English). 47: 1102-6. PMID 18161716 DOI: 10.1002/anie.200703521  1
2007 Johnson EC, Malito E, Shen Y, Pentelute B, Rich D, Florián J, Tang WJ, Kent SB. Insights from atomic-resolution X-ray structures of chemically synthesized HIV-1 protease in complex with inhibitors. Journal of Molecular Biology. 373: 573-86. PMID 17869270 DOI: 10.1016/j.jmb.2007.07.054  1
2007 Pentelute BL, Kent SB. Selective desulfurization of cysteine in the presence of Cys(Acm) in polypeptides obtained by native chemical ligation. Organic Letters. 9: 687-90. PMID 17286375 DOI: 10.1021/ol0630144  1
2006 Bang D, Pentelute BL, Kent SB. Kinetically controlled ligation for the convergent chemical synthesis of proteins. Angewandte Chemie (International Ed. in English). 45: 3985-8. PMID 16639756 DOI: 10.1002/anie.200600702  1
2006 Bang D, Pentelute BL, Gates ZP, Kent SB. Direct on-resin synthesis of peptide-alphathiophenylesters for use in native chemical ligation. Organic Letters. 8: 1049-52. PMID 16524265 DOI: 10.1021/ol052811j  1
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