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Brad L. Pentelute - Publications

Affiliations: 
Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
characterization of chemically modified proteins with modern biophysical techniques such as single-molecule electrophysiology, EPR, protein X-ray crystallography, protein NMR, and biological mass spectrometry
Website:
http://chemistry.mit.edu/people/pentelute-bradley
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Year Citation  Score
2020 Pomplun S, Gates ZP, Zhang G, Quartararo AJ, Pentelute BL. Discovery of Nucleic Acid Binding Molecules from Combinatorial Biohybrid Nucleobase Peptide Libraries. Journal of the American Chemical Society. 142: 19642-19651. PMID 33166454 DOI: 10.1021/jacs.0c08964  0.806
2020 Dhanjee HH, Saebi A, Buslov I, Loftis AR, Buchwald SL, Pentelute BL. Correction to "Protein-Protein Cross-Coupling via Palladium-Protein Oxidative Addition Complexes from Cysteine Residues". Journal of the American Chemical Society. PMID 32603593 DOI: 10.1021/Jacs.0C06703  0.445
2020 Quartararo AJ, Gates ZP, Somsen BA, Hartrampf N, Ye X, Shimada A, Kajihara Y, Ottmann C, Pentelute BL. Ultra-large chemical libraries for the discovery of high-affinity peptide binders. Nature Communications. 11: 3183. PMID 32576815 DOI: 10.1038/S41467-020-16920-3  0.807
2020 Lindemann WR, Mijalis AJ, Alonso JL, Borbat PP, Freed JH, Arnaout MA, Pentelute BL, Ortony JH. Conformational dynamics in extended RGD-containing peptides. Biomacromolecules. PMID 32469507 DOI: 10.1021/Acs.Biomac.0C00506  0.388
2020 Hartrampf N, Saebi A, Poskus M, Gates ZP, Callahan AJ, Cowfer AE, Hanna S, Antilla S, Schissel CK, Quartararo AJ, Ye X, Mijalis AJ, Simon MD, Loas A, Liu S, ... Pentelute BL, et al. Synthesis of proteins by automated flow chemistry. Science (New York, N.Y.). 368: 980-987. PMID 32467387 DOI: 10.1126/Science.Abb2491  0.787
2020 Albin JS, Pentelute BL. Efficient flow synthesis of human antimicrobial peptides. Australian Journal of Chemistry. 73: 380-388. PMID 32431323 DOI: 10.1071/Ch20043  0.362
2020 Dhanjee HH, Saebi A, Buslov I, Loftis AR, Buchwald SL, Pentelute BL. Protein-Protein Cross-Coupling via Palladium-Protein Oxidative Addition Complexes from Cysteine Residues. Journal of the American Chemical Society. PMID 32364380 DOI: 10.1021/Jacs.0C03143  0.468
2020 Pomplun S, Shugrue CR, Schmitt AM, Schissel CK, Farquhar CE, Pentelute BL. Secondary Amino Alcohols: Traceless Cleavable Linkers for Use in Affinity Capture and Release. Angewandte Chemie (International Ed. in English). 59: 11566-11572. PMID 32227406 DOI: 10.1002/Anie.202003478  0.788
2020 Loas A, Pentelute BL. Introduction: Peptide Chemistry. Chemical Reviews. 120: 3049-3050. PMID 32208601 DOI: 10.1021/acs.chemrev.0c00136  0.376
2020 Lindemann WR, Evans ED, Mijalis AJ, Saouaf OM, Pentelute BL, Ortony JH. Quantifying residue-specific conformational dynamics of a highly reactive 29-mer peptide. Scientific Reports. 10: 2597. PMID 32054898 DOI: 10.1038/S41598-020-59047-7  0.334
2020 Truex NL, Holden RL, Wang BY, Chen PG, Hanna S, Hu Z, Shetty K, Olive O, Neuberg D, Hacohen N, Keskin DB, Ott PA, Wu CJ, Pentelute BL. Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy. Scientific Reports. 10: 723. PMID 31959774 DOI: 10.1038/S41598-019-56943-5  0.358
2019 Fadzen CM, Holden R, Wolfe JM, Choo ZN, Schissel CK, Yao M, Hanson GJ, Pentelute BL. Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy. Biochemistry. PMID 31450889 DOI: 10.1021/Acs.Biochem.9B00413  0.804
2019 Touti F, Gates ZP, Bandyopadhyay A, Lautrette G, Pentelute BL. Author Correction: In-solution enrichment identifies peptide inhibitors of protein-protein interactions. Nature Chemical Biology. PMID 31086332 DOI: 10.1038/S41589-019-0302-X  0.786
2019 Touti F, Gates ZP, Bandyopdhyay A, Lautrette G, Pentelute BL. In-solution enrichment identifies peptide inhibitors of protein-protein interactions. Nature Chemical Biology. 15: 410-418. PMID 30886434 DOI: 10.1038/S41589-019-0245-2  0.786
2019 Evans ED, Gates ZP, Sun ZJ, Mijalis AJ, Pentelute BL. Conformational stabilization and rapid labeling of a 29-residue peptide by a small molecule reaction partner. Biochemistry. PMID 30724554 DOI: 10.1021/acs.biochem.8b00940  0.785
2019 von Spreckelsen N, Ghotmi Y, Fadzen C, Wolfe J, Hartrampf N, Bergmann S, Qu Y, Murrell E, Bononi F, Luyt L, Lamfers M, Ligon K, Chiocca E, Viapiano M, Pentelute BL, et al. DDIS-36. BTP-7, A NOVEL PEPTIDE FOR THERAPEUTIC TARGETING OF MALIGNANT BRAIN TUMORS Neuro-Oncology. 21: vi71-vi71. DOI: 10.1093/neuonc/noz175.287  0.723
2019 Zhang C, Vinogradova EV, Spokoyny AM, Buchwald SL, Pentelute BL. Arylierungschemie für die Biokonjugation Angewandte Chemie. 131: 4860-4892. DOI: 10.1002/Ange.201806009  0.593
2018 Pentelute B, Zhang C, Vinogradova E, Spokoyny A, Buchwald S. Arylation Chemistry for Bioconjugation. Angewandte Chemie (International Ed. in English). PMID 30399206 DOI: 10.1002/Anie.201806009  0.709
2018 Cohen DT, Zhang C, Fadzen CM, Mijalis AJ, Hie L, Johnson KD, Shriver Z, Plante O, Miller SJ, Buchwald SL, Pentelute BL. A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins. Nature Chemistry. PMID 30397320 DOI: 10.1038/S41557-018-0154-0  0.593
2018 Evans ED, Pentelute BL. Studies on a landscape of perfluoroaromatic-reactive peptides. Organic & Biomolecular Chemistry. PMID 30065992 DOI: 10.1039/c8ob01678j  0.369
2018 Touti F, Lautrette G, Johnson K, Delaney J, Wollacott A, Tissire H, Viswanathan K, Shriver Z, Mong S, Mijalis A, Plante O, Pentelute B. Antibody-Bactericidal Macrocyclic Peptide Conjugates to Target Gram Negative Bacteria. Chembiochem : a European Journal of Chemical Biology. PMID 29984452 DOI: 10.1002/Cbic.201800295  0.321
2018 Garcia-Castillo MD, Chinnapen DJ, Te Welscher YM, Gonzalez RJ, Softic S, Pacheco M, Mrsny RJ, Kahn CR, von Andrian UH, Lau J, Pentelute BL, Lencer WI. Mucosal absorption of therapeutic peptides by harnessing the endogenous sorting of glycosphingolipids. Elife. 7. PMID 29851380 DOI: 10.7554/Elife.34469  0.319
2018 Gates ZP, Vinogradov AA, Quartararo AJ, Bandyopadhyay A, Choo ZN, Evans ED, Halloran KH, Mijalis AJ, Mong SK, Simon MD, Standley EA, Styduhar ED, Tasker SZ, Touti F, Weber JM, ... ... Pentelute BL, et al. Xenoprotein engineering via synthetic libraries. Proceedings of the National Academy of Sciences of the United States of America. PMID 29784819 DOI: 10.1073/Pnas.1722633115  0.79
2018 Slough DP, McHugh SM, Cummings AE, Dai P, Pentelute BL, Kritzer JA, Lin YS. Designing Well-Structured Cyclic Pentapeptides Based on Sequence-Structure Relationships. The Journal of Physical Chemistry. B. PMID 29589926 DOI: 10.1021/Acs.Jpcb.8B01747  0.362
2018 Dunkelmann DL, Hirata Y, Totaro KA, Cohen DT, Zhang C, Gates ZP, Pentelute BL. Amide-forming chemical ligation via-acyl hydroxamic acids. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581295 DOI: 10.1073/Pnas.1718356115  0.785
2018 Pentelute B, Zhang C, Dai P, Vinogradov A, Gates Z. Site-Selective Cysteine-Cyclooctyne Conjugation. Angewandte Chemie (International Ed. in English). PMID 29575377 DOI: 10.1002/Anie.201800860  0.801
2018 Wolfe JM, Fadzen CM, Holden RL, Yao M, Hanson GJ, Pentelute B. Perfluoroaryl Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides. Angewandte Chemie (International Ed. in English). PMID 29479836 DOI: 10.1002/anie.201801167  0.382
2018 Kubota K, Dai P, Pentelute BL, Buchwald SL. Palladium Oxidative Addition Complexes for Peptide and Protein Crosslinking. Journal of the American Chemical Society. PMID 29406701 DOI: 10.1021/Jacs.8B00172  0.585
2018 Wedekind JE, Belashov IA, Crawford DW, Lavender CE, Dai P, Beardslee PC, Mathews DH, Pentelute BL, McNaughton BR. Structure of HIV-1 TAR in complex with a lab-evolved protein provides insight into RNA recognition and synthesis of a constrained peptide that impairs transcription Acta Crystallographica Section a Foundations and Advances. 74: a345-a345. DOI: 10.1107/S0108767318096551  0.301
2017 Evans ED, Pentelute BL. Discovery of a 29-amino-acid reactive abiotic peptide for selective cysteine arylation. Acs Chemical Biology. PMID 29283243 DOI: 10.1021/acschembio.7b00520  0.439
2017 Rojas AJ, Zhang C, Vinogradova EV, Buchwald NH, Reilly J, Pentelute BL, Buchwald SL. Divergent unprotected peptide macrocyclisation by palladium-mediated cysteine arylation. Chemical Science. 8: 4257-4263. PMID 29081961 DOI: 10.1039/C6Sc05454D  0.618
2017 Mong S, Cochran F, Yu H, Graziano ZA, Lin YS, Cochran JR, Pentelute BL. Heterochiral Knottin Protein: Folding and Solution Structure. Biochemistry. PMID 28952732 DOI: 10.1021/Acs.Biochem.7B00722  0.331
2017 Vinogradov AA, Gates ZP, Zhang C, Quartararo AJ, Halloran KH, Pentelute BL. Library design-facilitated high-throughput sequencing of synthetic peptide libraries. Acs Combinatorial Science. PMID 28892357 DOI: 10.1021/Acscombsci.7B00109  0.773
2017 Dai P, Williams JK, Zhang C, Welborn M, Shepherd JJ, Zhu T, Van Voorhis T, Hong M, Pentelute BL. A structural and mechanistic study of π-clamp-mediated cysteine perfluoroarylation. Scientific Reports. 7: 7954. PMID 28801573 DOI: 10.1038/S41598-017-08402-2  0.429
2017 Rojas AJ, Pentelute BL, Buchwald SL. Water-Soluble Palladium Reagents for Cysteine S-Arylation under Ambient Aqueous Conditions. Organic Letters. PMID 28777001 DOI: 10.1021/Acs.Orglett.7B01911  0.512
2017 Mijalis AJ, Thomas DA, Simon MD, Adamo A, Beaumont R, Jensen KF, Pentelute BL. A fully automated flow-based approach for accelerated peptide synthesis. Nature Chemical Biology. PMID 28244989 DOI: 10.1038/nchembio.2318  0.399
2017 Lee HG, Lautrette G, Pentelute BL, Buchwald SL. Palladium-Mediated Arylation of Lysine in Unprotected Peptides. Angewandte Chemie (International Ed. in English). 56: 3177-3181. PMID 28206688 DOI: 10.1002/Anie.201611202  0.562
2016 Dai P, Zhang C, Welborn M, Shepherd JJ, Zhu T, Van Voorhis T, Pentelute BL. Salt Effect Accelerates Site-Selective Cysteine Bioconjugation. Acs Central Science. 2: 637-646. PMID 27725962 DOI: 10.1021/Acscentsci.6B00180  0.313
2016 Simon MD, Maki Y, Vinogradov AA, Zhang C, Yu H, Lin YS, Kajihara Y, Pentelute BL. D-amino acid scan of two small proteins. Journal of the American Chemical Society. PMID 27494078 DOI: 10.1021/Jacs.6B03765  0.346
2016 Rabideau AE, Pentelute BL. Delivery of Non-Native Cargo into Mammalian Cells Using Anthrax Lethal Toxin. Acs Chemical Biology. 11: 1490-501. PMID 27055654 DOI: 10.1021/acschembio.6b00169  0.366
2016 Totaro K, Liao X, Bhattacharya K, Finneman JI, Sperry JB, Massa MA, Thorn J, Ho SV, Pentelute BL. Systematic Investigation of EDC/sNHS-Mediated Bioconjugation Reactions for Carboxylated Peptide Substrates. Bioconjugate Chemistry. PMID 26974183 DOI: 10.1021/Acs.Bioconjchem.6B00043  0.392
2016 Lühmann T, Mong SK, Simon MD, Meinel L, Pentelute BL. A perfluoroaromatic abiotic analog of H2 relaxin enabled by rapid flow-based peptide synthesis. Organic & Biomolecular Chemistry. 14: 3345-9. PMID 26954512 DOI: 10.1039/c6ob00208k  0.342
2016 Vinogradov AA, Choo ZN, Totaro KA, Pentelute BL. Macrocyclization of Unprotected Peptide Isocyanates. Organic Letters. 18: 1226-9. PMID 26948900 DOI: 10.1021/acs.orglett.5b03626  0.417
2016 Vinogradov AA, Simon MD, Pentelute BL. C-Terminal Modification of Fully Unprotected Peptide Hydrazides via in Situ Generation of Isocyanates. Organic Letters. 18: 1222-5. PMID 26948719 DOI: 10.1021/acs.orglett.5b03625  0.42
2016 Zhang C, Welborn M, Zhu T, Yang NJ, Santos MS, Van Voorhis T, Pentelute BL. π-Clamp-mediated cysteine conjugation. Nature Chemistry. 8: 120-8. PMID 26791894 DOI: 10.1038/Nchem.2413  0.319
2016 Cho C, Kasai K, Wolfe J, Hornburg K, Bononi F, Luyt L, Pentelute B, Viapiano M, Chiocca E, Lawler S. PS2 - 178 Brevican-Specific Peptides for the Development of Next-Generation Targeted Theranostics for High Grade Gliomas Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 43: S14-S14. DOI: 10.1017/cjn.2016.369  0.315
2015 Vinogradova EV, Zhang C, Spokoyny AM, Pentelute BL, Buchwald SL. Organometallic palladium reagents for cysteine bioconjugation. Nature. 526: 687-91. PMID 26511579 DOI: 10.1038/Nature15739  0.702
2015 Cohen DT, Zhang C, Pentelute BL, Buchwald SL. An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides. Journal of the American Chemical Society. 137: 9784-7. PMID 26225900 DOI: 10.1021/Jacs.5B05447  0.559
2015 Rabideau AE, Liao X, Akçay G, Pentelute BL. Translocation of Non-Canonical Polypeptides into Cells Using Protective Antigen. Scientific Reports. 5: 11944. PMID 26178180 DOI: 10.1038/srep11944  0.366
2015 Bunker RD, Mandal K, Bashiri G, Chaston JJ, Pentelute BL, Lott JS, Kent SB, Baker EN. A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography. Proceedings of the National Academy of Sciences of the United States of America. 112: 4310-5. PMID 25831534 DOI: 10.1073/Pnas.1422387112  0.493
2015 Cho C, Bononi F, Wolfe J, Pentelute B, Luyt L, Viapiano M, Chiocca EA, Lawler S. ATPS-08DISCOVERY OF NOVEL GLIOMA-TARGETING PEPTIDES USING A HIGH-THROUGHPUT MICROFLUIDIC MAGNETIC-ACTIVATED SORTER Neuro-Oncology. 17: v19.4-v19. DOI: 10.1093/Neuonc/Nov204.08  0.333
2015 Cohen DT, Zhang C, Pentelute BL, Buchwald SL. An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides Journal of the American Chemical Society. 137: 9784-9787. DOI: 10.1021/jacs.5b05447  0.521
2014 Zhang C, Dai P, Spokoyny AM, Pentelute BL. Enzyme-catalyzed macrocyclization of long unprotected peptides. Organic Letters. 16: 3652-5. PMID 25002256 DOI: 10.1021/Ol501609Y  0.71
2014 Mong SK, Vinogradov AA, Simon MD, Pentelute BL. Rapid total synthesis of DARPin pE59 and barnase. Chembiochem : a European Journal of Chemical Biology. 15: 721-33. PMID 24616257 DOI: 10.1002/cbic.201300797  0.441
2014 Simon MD, Heider PL, Adamo A, Vinogradov AA, Mong SK, Li X, Berger T, Policarpo RL, Zhang C, Zou Y, Liao X, Spokoyny AM, Jensen KF, Pentelute BL. Rapid flow-based peptide synthesis. Chembiochem : a European Journal of Chemical Biology. 15: 713-20. PMID 24616230 DOI: 10.1002/Cbic.201300796  0.693
2014 Zou Y, Spokoyny AM, Zhang C, Simon MD, Yu H, Lin YS, Pentelute BL. Convergent diversity-oriented side-chain macrocyclization scan for unprotected polypeptides. Organic & Biomolecular Chemistry. 12: 566-73. PMID 24310320 DOI: 10.1039/C3Ob42168F  0.724
2013 Zhang C, Spokoyny AM, Zou Y, Simon MD, Pentelute BL. Enzymatic "click" ligation: selective cysteine modification in polypeptides enabled by promiscuous glutathione S-transferase. Angewandte Chemie (International Ed. in English). 52: 14001-5. PMID 24222025 DOI: 10.1002/Anie.201306430  0.632
2013 Spokoyny AM, Zou Y, Ling JJ, Yu H, Lin YS, Pentelute BL. A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling. Journal of the American Chemical Society. 135: 5946-9. PMID 23560559 DOI: 10.1021/Ja400119T  0.692
2013 Akkaladevi N, Hinton-Chollet L, Katayama H, Mitchell J, Szerszen L, Mukherjee S, Gogol EP, Pentelute BL, Collier RJ, Fisher MT. Assembly of anthrax toxin pore: lethal-factor complexes into lipid nanodiscs. Protein Science : a Publication of the Protein Society. 22: 492-501. PMID 23389868 DOI: 10.1002/Pro.2231  0.304
2012 Ling JJ, Policarpo RL, Rabideau AE, Liao X, Pentelute BL. Protein thioester synthesis enabled by sortase. Journal of the American Chemical Society. 134: 10749-52. PMID 22686546 DOI: 10.1021/ja302354v  0.334
2012 Kent S, Sohma Y, Liu S, Bang D, Pentelute B, Mandal K. Through the looking glass--a new world of proteins enabled by chemical synthesis. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 428-36. PMID 22674813 DOI: 10.1002/Psc.2421  0.749
2012 Mandal K, Pentelute BL, Bang D, Gates ZP, Torbeev VY, Kent SB. Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology. Angewandte Chemie (International Ed. in English). 51: 1481-6. PMID 22213444 DOI: 10.1002/Anie.201107846  0.766
2012 Sawaya MR, Pentelute BL, Kent SB, Yeates TO. Single-wavelength phasing strategy for quasi-racemic protein crystal diffraction data. Acta Crystallographica. Section D, Biological Crystallography. 68: 62-8. PMID 22194334 DOI: 10.1107/S0907444911049985  0.532
2012 Liu S, Pentelute BL, Kent SB. Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin. Angewandte Chemie (International Ed. in English). 51: 993-9. PMID 22180156 DOI: 10.1002/Anie.201106060  0.542
2011 Fischer A, Holden MA, Pentelute BL, Collier RJ. Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers. Proceedings of the National Academy of Sciences of the United States of America. 108: 16577-81. PMID 21949363 DOI: 10.1073/Pnas.1113074108  0.34
2011 Lee J, Kwon Y, Pentelute BL, Bang D. Use of model peptide reactions for the characterization of kinetically controlled ligation. Bioconjugate Chemistry. 22: 1645-9. PMID 21740060 DOI: 10.1021/Bc2002242  0.695
2011 Pentelute BL, Sharma O, Collier RJ. Chemical dissection of protein translocation through the anthrax toxin pore. Angewandte Chemie (International Ed. in English). 50: 2294-6. PMID 21351339 DOI: 10.1002/Anie.201006460  0.36
2010 Pentelute BL, Mandal K, Gates ZP, Sawaya MR, Yeates TO, Kent SB. Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography. Chemical Communications (Cambridge, England). 46: 8174-6. PMID 20877851 DOI: 10.1039/C0Cc03148H  0.804
2010 Pentelute BL, Barker AP, Janowiak BE, Kent SB, Collier RJ. A semisynthesis platform for investigating structure-function relationships in the N-terminal domain of the anthrax Lethal Factor. Acs Chemical Biology. 5: 359-64. PMID 20180595 DOI: 10.1021/Cb100003R  0.529
2009 Mandal K, Pentelute BL, Tereshko V, Thammavongsa V, Schneewind O, Kossiakoff AA, Kent SB. Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods. Protein Science : a Publication of the Protein Society. 18: 1146-54. PMID 19472324 DOI: 10.1002/Pro.127  0.593
2009 Mandal K, Pentelute BL, Tereshko V, Kossiakoff AA, Kent SB. X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods. Journal of the American Chemical Society. 131: 1362-3. PMID 19133782 DOI: 10.1021/Ja8077973  0.592
2008 Pentelute BL, Gates ZP, Tereshko V, Dashnau JL, Vanderkooi JM, Kossiakoff AA, Kent SB. X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers. Journal of the American Chemical Society. 130: 9695-701. PMID 18598029 DOI: 10.1021/Ja8013538  0.784
2008 Pentelute BL, Gates ZP, Dashnau JL, Vanderkooi JM, Kent SB. Mirror image forms of snow flea antifreeze protein prepared by total chemical synthesis have identical antifreeze activities. Journal of the American Chemical Society. 130: 9702-7. PMID 18598026 DOI: 10.1021/Ja801352J  0.818
2008 Sohma Y, Pentelute BL, Whittaker J, Hua QX, Whittaker LJ, Weiss MA, Kent SB. Comparative properties of insulin-like growth factor 1 (IGF-1) and [Gly7D-Ala]IGF-1 prepared by total chemical synthesis. Angewandte Chemie (International Ed. in English). 47: 1102-6. PMID 18161716 DOI: 10.1002/Anie.200703521  0.484
2007 Johnson EC, Malito E, Shen Y, Pentelute B, Rich D, Florián J, Tang WJ, Kent SB. Insights from atomic-resolution X-ray structures of chemically synthesized HIV-1 protease in complex with inhibitors. Journal of Molecular Biology. 373: 573-86. PMID 17869270 DOI: 10.1016/J.Jmb.2007.07.054  0.68
2007 Pentelute BL, Kent SB. Selective desulfurization of cysteine in the presence of Cys(Acm) in polypeptides obtained by native chemical ligation. Organic Letters. 9: 687-90. PMID 17286375 DOI: 10.1021/Ol0630144  0.698
2006 Bang D, Pentelute BL, Kent SB. Kinetically controlled ligation for the convergent chemical synthesis of proteins. Angewandte Chemie (International Ed. in English). 45: 3985-8. PMID 16639756 DOI: 10.1002/Anie.200600702  0.694
2006 Bang D, Pentelute BL, Gates ZP, Kent SB. Direct on-resin synthesis of peptide-alphathiophenylesters for use in native chemical ligation. Organic Letters. 8: 1049-52. PMID 16524265 DOI: 10.1021/Ol052811J  0.802
2006 Bang D, Pentelute BL, Kent SBH. Cover Picture: Kinetically Controlled Ligation for the Convergent Chemical Synthesis of Proteins (Angew. Chem. Int. Ed. 24/2006) Angewandte Chemie International Edition. 45: 3887-3887. DOI: 10.1002/Anie.200690082  0.604
2006 Bang D, Pentelute BL, Kent SBH. Titelbild: Kinetically Controlled Ligation for the Convergent Chemical Synthesis of Proteins (Angew. Chem. 24/2006) Angewandte Chemie. 118: 3991-3991. DOI: 10.1002/Ange.200690082  0.61
Low-probability matches (unlikely to be authored by this person)
2016 Cho C, Kasai K, Wolfe J, Hornburg K, Bononi F, Luyt L, Pentelute B, Viapiano M, Chiocca EA, Lawler SE. EXTH-51. BREVICAN-SPECIFIC PEPTIDES FOR THE DEVELOPMENT OF NEXT-GENERATION TARGETED THERANOSTICS FOR MALIGNANT GLIOMAS Neuro-Oncology. 18: vi70-vi70. DOI: 10.1093/Neuonc/Now212.293  0.296
2018 Wolfe JM, Fadzen CM, Choo ZN, Holden RL, Yao M, Hanson GJ, Pentelute BL. Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery. Acs Central Science. 4: 512-520. PMID 29721534 DOI: 10.1021/acscentsci.8b00098  0.275
2018 Moynihan KD, Holden RL, Mehta NK, Wang C, Karver MR, Dinter J, Liang S, Abraham W, Melo MB, Zhang AQ, Li N, Le Gall S, Pentelute B, Irvine DJ. Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability. Cancer Immunology Research. PMID 29915023 DOI: 10.1158/2326-6066.Cir-17-0607  0.274
2013 Gogol EP, Akkaladevi N, Szerszen L, Mukherjee S, Chollet-Hinton L, Katayama H, Pentelute BL, Collier RJ, Fisher MT. Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryo-electron microscopy. Protein Science : a Publication of the Protein Society. 22: 586-94. PMID 23494942 DOI: 10.1002/Pro.2241  0.271
2018 Belashov IA, Crawford DW, Cavender CE, Dai P, Beardslee PC, Mathews DH, Pentelute BL, McNaughton BR, Wedekind JE. Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription. Nucleic Acids Research. PMID 29961805 DOI: 10.1093/Nar/Gky529  0.264
2015 Rabideau AE, Pentelute BL. A d-Amino Acid at the N-Terminus of a Protein Abrogates Its Degradation by the N-End Rule Pathway. Acs Central Science. 1: 423-430. PMID 26807441 DOI: 10.1021/ACSCENTSCI.5B00308  0.24
2013 Naik S, Brock S, Akkaladevi N, Tally J, McGinn-Straub W, Zhang N, Gao P, Gogol EP, Pentelute BL, Collier RJ, Fisher MT. Monitoring the kinetics of the pH-driven transition of the anthrax toxin prepore to the pore by biolayer interferometry and surface plasmon resonance. Biochemistry. 52: 6335-47. PMID 23964683 DOI: 10.1021/Bi400705N  0.239
2018 Cho C, Ghotmi Y, Fadzan C, Wolfe J, Bergmann S, Qu Y, Murrell E, Bononi F, Luyt L, Chiocca EA, Viapiano M, Pentelute B, Lawler S. DDIS-26. BTP-7, A NOVEL PEPTIDE FOR THERAPEUTIC TARGETING OF MALIGNANT BRAIN TUMORS Neuro-Oncology. 20: vi74-vi74. DOI: 10.1093/Neuonc/Noz175.287  0.236
2017 Cho C, Ghotmi Y, Fazden C, Wolfe J, Bononi F, Murrell E, Luyt L, Viapiano M, Pentelute B, Chiocca EA, Lawler SE. DDIS-19. NOVEL PEPTIDE HOMING TO GLIOMA-SPECIFIC ISOFORM OF BREVICAN SELECTIVELY TARGETS MALIGNANT BRAIN TUMORS Neuro-Oncology. 19: vi62-vi63. DOI: 10.1093/Neuonc/Nox168.254  0.235
2014 Liao X, Rabideau AE, Pentelute BL. Delivery of antibody mimics into mammalian cells via anthrax toxin protective antigen. Chembiochem : a European Journal of Chemical Biology. 15: 2458-66. PMID 25250705 DOI: 10.1002/cbic.201402290  0.229
2017 Fadzen C, Wolfe J, Cho CF, Chiocca EA, Lawler S, Pentelute BL. Perfluoroarene-Based Peptide Macrocycles to Enhance Penetration Across the Blood-Brain Barrier. Journal of the American Chemical Society. PMID 28992407 DOI: 10.1021/Jacs.7B09790  0.225
2014 Policarpo RL, Kang H, Liao X, Rabideau AE, Simon MD, Pentelute BL. Flow-based enzymatic ligation by sortase A. Angewandte Chemie (International Ed. in English). 53: 9203-8. PMID 24989829 DOI: 10.1002/anie.201403582  0.219
2020 Fadzen CM, Wolfe JM, Zhou W, Cho CF, von Spreckelsen N, Hutchinson KT, Lee YC, Chiocca EA, Lawler S, Yilmaz ÖH, Lippard SJ, Pentelute BL. A Platinum(IV) Prodrug - Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain. Journal of Medicinal Chemistry. PMID 32410451 DOI: 10.1021/Acs.Jmedchem.0C00022  0.21
2017 Cho CF, Wolfe JM, Fadzen CM, Calligaris D, Hornburg K, Chiocca EA, Agar NYR, Pentelute BL, Lawler SE. Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents. Nature Communications. 8: 15623. PMID 28585535 DOI: 10.1038/Ncomms15623  0.203
2018 Wang B, Dai P, Ding D, Del Rosario A, Grant RA, Pentelute BL, Laub MT. Affinity-based capture and identification of protein effectors of the growth regulator ppGpp. Nature Chemical Biology. PMID 30559427 DOI: 10.1038/S41589-018-0183-4  0.198
2018 Machen AJ, O'Neil PT, Pentelute BL, Villar MT, Artigues A, Fisher MT. Analyzing Dynamic Protein Complexes Assembled On and Released From Biolayer Interferometry Biosensor Using Mass Spectrometry and Electron Microscopy. Journal of Visualized Experiments : Jove. PMID 30124667 DOI: 10.3791/57902  0.178
2020 Loftis AR, Santos MS, Truex NL, Biancucci M, Satchell KJF, Pentelute BL. Anthrax protective antigen retargeted with single-chain variable fragments delivers enzymes to pancreatic cancer cells. Chembiochem : a European Journal of Chemical Biology. PMID 32369652 DOI: 10.1002/cbic.202000201  0.172
2013 Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, et al. Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science (New York, N.Y.). 339: 1216-9. PMID 23471411 DOI: 10.1126/Science.1231097  0.167
2020 Lu Z, Paolella BR, Truex NL, Loftis AR, Liao X, Rabideau AE, Brown MS, Busanovich J, Beroukhim R, Pentelute BL. Targeting cancer gene dependencies with anthrax-mediated delivery of peptide nucleic acids. Acs Chemical Biology. PMID 32348107 DOI: 10.1021/Acschembio.9B01027  0.161
2016 Jiang J, Pentelute BL, Collier RJ, Zhou ZH. 2.9-Å Resolution Structure of Anthrax Protective Antigen Pore Determined by Cryo Electron Microscopy Biophysical Journal. 110: 158a. DOI: 10.1016/j.bpj.2015.11.886  0.16
2015 Jiang J, Pentelute BL, Collier RJ, Zhou ZH. Atomic structure of anthrax protective antigen pore elucidates toxin translocation. Nature. 521: 545-9. PMID 25778700 DOI: 10.1038/nature14247  0.156
2017 Elkins MR, Williams JK, Gelenter MD, Dai P, Kwon B, Sergeyev IV, Pentelute BL, Hong M. Cholesterol-binding site of the influenza M2 protein in lipid bilayers from solid-state NMR. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158386 DOI: 10.1073/Pnas.1715127114  0.126
2018 Hartmann S, Lopez Cruz R, Alameh S, Ho CC, Rabideau AE, Pentelute BL, Bradley KA, Martchenko M. Characterization of a novel piperidine-based inhibitor of cathepsin B-dependent bacterial toxins and viruses. Acs Infectious Diseases. PMID 29749721 DOI: 10.1021/Acsinfecdis.8B00053  0.124
2016 Pentelute BL, Wang L. Editorial overview: Chemistry for biopolymers to investigate and even move beyond nature. Current Opinion in Chemical Biology. PMID 27751659 DOI: 10.1016/J.Cbpa.2016.09.017  0.122
2015 Vinogradov AA, Evans ED, Pentelute BL. Total synthesis and biochemical characterization of mirror image barnase Chemical Science. 6: 2997-3002. DOI: 10.1039/c4sc03877k  0.122
2015 Akkaladevi N, Mukherjee S, Katayama H, Janowiak B, Patel D, Gogol EP, Pentelute BL, John Collier R, Fisher MT. Following Natures Lead: On the Construction of Membrane-Inserted Toxins in Lipid Bilayer Nanodiscs. The Journal of Membrane Biology. 248: 595-607. PMID 25578459 DOI: 10.1007/S00232-014-9768-3  0.12
2017 Biancucci M, Rabideau AE, Lu Z, Loftis AR, Pentelute BL, Satchell KJF. Substrate recognition of MARTX Ras/Rap1 specific endopeptidase. Biochemistry. PMID 28459538 DOI: 10.1021/acs.biochem.7b00246  0.114
2019 Wang B, Dai P, Ding D, Del Rosario A, Grant RA, Pentelute BL, Laub MT. Author Correction: Affinity-based capture and identification of protein effectors of the growth regulator ppGpp. Nature Chemical Biology. PMID 31076737 DOI: 10.1038/S41589-019-0296-4  0.103
2020 Mandala VS, Loftis AR, Shcherbakov AA, Pentelute BL, Hong M. Atomic structures of closed and open influenza B M2 proton channel reveal the conduction mechanism. Nature Structural & Molecular Biology. PMID 32015551 DOI: 10.1038/S41594-019-0371-2  0.075
2018 Bergmann S, Lawler SE, Qu Y, Fadzen CM, Wolfe JM, Regan MS, Pentelute BL, Agar NYR, Cho CF. Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics. Nature Protocols. PMID 30382243 DOI: 10.1038/s41596-018-0066-x  0.074
2019 Jack S, Madhivanan K, Ramadesikan S, Subramanian S, Edwards DF, Elzey BD, Dhawan D, McCluskey A, Kischuk EM, Loftis AR, Truex N, Santos M, Lu M, Rabideau A, Pentelute B, et al. A Novel, Safe, Fast, Efficient Treatment for Her2-positive and Negative Bladder Cancer Utilizing an EGF-Anthrax Toxin Chimera. International Journal of Cancer. PMID 31584195 DOI: 10.1002/Ijc.32719  0.073
2019 Romano KP, Warrier T, Poulsen BE, Nguyen PH, Loftis AR, Saebi A, Pentelute BL, Hung DT. Mutations in confer cross-resistance between the LptD inhibitor POL7080 and colistin in . Antimicrobial Agents and Chemotherapy. PMID 31235628 DOI: 10.1128/Aac.00511-19  0.064
2016 Cho C, Wolfe J, Fazden C, Hornburg K, Chiocca EA, Pentelute B, Lawler SE. DDIS-12. A FACILE, ROBUST AND PREDICTIVE IN VITRO BLOOD-BRAIN-BARRIER MODEL FOR HIGH-THROUGHPUT SCREENING AND DISCOVERY OF BRAIN-PENETRATING AGENTS Neuro-Oncology. 18: vi49-vi50. DOI: 10.1093/Neuonc/Now212.203  0.064
2015 Rabideau AE, Liao X, Pentelute BL. Delivery of mirror image polypeptides into cells Chemical Science. 6: 648-653. DOI: 10.1039/c4sc02078b  0.063
2017 Cho C, Wolfe J, Fadzen C, Calligaris D, Hornburg K, Chiocca EA, Agar N, Pentelute B, Lawler S. SCDT-02. BLOOD-BRAIN-BARRIER SPHEROIDS AS AN IN VITRO SCREENING PLATFORM FOR BRAIN-PENETRATING AGENTS Neuro-Oncology. 19: vi265-vi265. DOI: 10.1093/Neuonc/Nox168.1086  0.046
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