| Year |
Citation |
Score |
| 2023 |
Yammine KM, Abularach SM, Kim SY, Bikovtseva AA, Lilianty J, Butty VL, Schiavoni RP, Bateman JF, Lamandé SR, Shoulders MD. Chondrodysplasia-inducing p.Gly1170Ser causes an ER storage defect without associated unfolded protein response in a human cartilage model. Biorxiv : the Preprint Server For Biology. PMID 37905055 DOI: 10.1101/2023.10.19.562780 |
0.788 |
|
| 2023 |
Yoon J, Zhang YM, Her C, Grant RA, Ponomarenko AM, Ackermann BE, Debelouchina GT, Shoulders MD. The Immune-Evasive Proline 283 Substitution in Influenza Nucleoprotein Increases Aggregation Propensity Without Altering the Native Structure. Biorxiv : the Preprint Server For Biology. PMID 37745335 DOI: 10.1101/2023.09.08.556894 |
0.785 |
|
| 2023 |
Yoon J, Patrick JE, Ogbunugafor CB, Shoulders MD. Viral Evolution Shaped by Host Proteostasis Networks. Annual Review of Virology. PMID 37071930 DOI: 10.1146/annurev-virology-100220-112120 |
0.812 |
|
| 2023 |
Mengiste AA, Wilson RH, Weissman RF, Papa Iii LJ, Hendel SJ, Moore CL, Butty VL, Shoulders MD. Expanded MutaT7 toolkit efficiently and simultaneously accesses all possible transition mutations in bacteria. Nucleic Acids Research. PMID 36715334 DOI: 10.1093/nar/gkad003 |
0.774 |
|
| 2023 |
Yammine KM, Mirda Abularach S, Sampurno L, Bateman JF, Lamandé SR, Shoulders MD. Using CRISPR/Cas9 to generate a heterozygous COL2A1 p.R719C iPSC line (MCRIi019-A-6) model of human precocious osteoarthritis. Stem Cell Research. 67: 103020. PMID 36682125 DOI: 10.1016/j.scr.2023.103020 |
0.775 |
|
| 2022 |
Molina RS, Rix G, Mengiste AA, Alvarez B, Seo D, Chen H, Hurtado J, Zhang Q, Donato García-García J, Heins ZJ, Almhjell PJ, Arnold FH, Khalil AS, Hanson AD, Dueber JE, ... ... Shoulders MD, et al. In vivo hypermutation and continuous evolution. Nature Reviews. Methods Primers. 2. PMID 37073402 DOI: 10.1038/s43586-022-00130-w |
0.771 |
|
| 2022 |
Choudhury A, Ratna A, Lim A, Sebastian RM, Moore CL, Filliol AA, Bledsoe J, Dai C, Schwabe RF, Shoulders MD, Mandrekar P. Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis. Hepatology Communications. PMID 35945902 DOI: 10.1002/hep4.2058 |
0.66 |
|
| 2022 |
King DT, Serrano-Negrón JE, Zhu Y, Moore CL, Shoulders MD, Foster LJ, Vocadlo DJ. Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome. Journal of the American Chemical Society. PMID 35230102 DOI: 10.1021/jacs.1c10621 |
0.442 |
|
| 2022 |
Bateman JF, Shoulders MD, Lamandé SR. Collagen misfolding mutations: the contribution of the unfolded protein response to the molecular pathology. Connective Tissue Research. 63: 210-227. PMID 35225118 DOI: 10.1080/03008207.2022.2036735 |
0.314 |
|
| 2022 |
Yoon J, Nekongo EE, Patrick JE, Hui T, Phillips AM, Ponomarenko AI, Hendel SJ, Sebastian RM, Zhang YM, Butty VL, Ogbunugafor CB, Lin YS, Shoulders MD. The endoplasmic reticulum proteostasis network profoundly shapes the protein sequence space accessible to HIV envelope. Plos Biology. 20: e3001569. PMID 35180219 DOI: 10.1371/journal.pbio.3001569 |
0.773 |
|
| 2021 |
Hendel SJ, Shoulders MD. Directed evolution in mammalian cells. Nature Methods. 18: 346-357. PMID 33828274 DOI: 10.1038/s41592-021-01090-x |
0.78 |
|
| 2021 |
Li RC, Wong MY, DiChiara AS, Hosseini AS, Shoulders MD. Collagen's enigmatic, highly conserved -glycan has an essential proteostatic function. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33674390 DOI: 10.1073/pnas.2026608118 |
0.793 |
|
| 2020 |
Kung LHW, Sampurno L, Yammine KM, Graham A, McDonald P, Bateman JF, Shoulders MD, Lamandé SR. CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A. Stem Cell Research. 48: 101962. PMID 33002832 DOI: 10.1016/J.Scr.2020.101962 |
0.781 |
|
| 2020 |
Nekongo EE, Ponomarenko AI, Dewal MB, Butty VL, Browne EP, Shoulders MD. HSF1 Activation Can Restrict HIV Replication. Acs Infectious Diseases. PMID 32502335 DOI: 10.1021/Acsinfecdis.0C00166 |
0.768 |
|
| 2020 |
Doan ND, Hosseini AS, Bikovtseva AA, Huang MS, DiChiara AS, Papa LJ, Koller A, Shoulders MD. Elucidation of proteostasis defects caused by osteogenesis imperfecta mutations in the collagen-α2(I) C-propeptide domain. The Journal of Biological Chemistry. PMID 32482890 DOI: 10.1074/Jbc.Ra120.014071 |
0.755 |
|
| 2020 |
Sebastian RM, Shoulders MD. Chemical Biology Framework to Illuminate Proteostasis. Annual Review of Biochemistry. PMID 32097570 DOI: 10.1146/Annurev-Biochem-013118-111552 |
0.664 |
|
| 2020 |
Bikovtseva A, Doan N, DiChiara AS, Del Rosario A, Shoulders MD. Mutation‐Dependent Capacity of the ER Proteostasis Network to Quality Control Disease‐Causing Collagen Misfolding The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09187 |
0.765 |
|
| 2019 |
Papa LJ, Shoulders MD. Genetic Engineering by DNA Recombineering. Current Protocols in Chemical Biology. 11: e70. PMID 31483098 DOI: 10.1002/Cpch.70 |
0.768 |
|
| 2019 |
Wong MY, Shoulders MD. Targeting defective proteostasis in the collagenopathies. Current Opinion in Chemical Biology. 50: 80-88. PMID 31028939 DOI: 10.1016/J.Cbpa.2019.02.021 |
0.643 |
|
| 2019 |
Doan ND, DiChiara AS, Del Rosario AM, Schiavoni RP, Shoulders MD. Mass Spectrometry-Based Proteomics to Define Intracellular Collagen Interactomes. Methods in Molecular Biology (Clifton, N.J.). 1944: 95-114. PMID 30840237 DOI: 10.1007/978-1-4939-9095-5_7 |
0.776 |
|
| 2019 |
Liebelt F, Sebastian RM, Moore CL, Mulder MPC, Ovaa H, Shoulders MD, Vertegaal ACO. SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock. Cell Reports. 26: 236-249.e4. PMID 30605679 DOI: 10.1016/J.Celrep.2018.12.027 |
0.703 |
|
| 2018 |
Berman C, Papa LJ, Hendel SJ, Moore CL, Suen PH, Weickhardt AF, Doan ND, Kumar CM, Uil TG, Butty VL, Hoeben RC, Shoulders MD. An Adaptable Platform for Directed Evolution in Human Cells. Journal of the American Chemical Society. PMID 30427676 DOI: 10.1021/Jacs.8B10937 |
0.757 |
|
| 2018 |
Richardson CER, Nolan EM, Shoulders MD, Lippard SJ. A sensitive, non-radioactive assay for Zn(II) uptake into metazoan cells. Biochemistry. PMID 30381945 DOI: 10.1021/Acs.Biochem.8B01043 |
0.389 |
|
| 2018 |
DiChiara AS, Li RC, Suen PH, Hosseini AS, Taylor RJ, Weickhardt AF, Malhotra D, McCaslin DR, Shoulders MD. A cysteine-based molecular code informs collagen C-propeptide assembly. Nature Communications. 9: 4206. PMID 30310058 DOI: 10.1038/S41467-018-06185-2 |
0.778 |
|
| 2018 |
Wong MY, Chen K, Antonopoulos A, Kasper BT, Dewal MB, Taylor RJ, Whittaker CA, Hein PP, Dell A, Genereux JC, Haslam SM, Mahal LK, Shoulders MD. XBP1s activation can globally remodel N-glycan structure distribution patterns. Proceedings of the National Academy of Sciences of the United States of America. PMID 30305426 DOI: 10.1073/Pnas.1805425115 |
0.786 |
|
| 2018 |
Phillips AM, Ponomarenko AI, Chen K, Ashenberg O, Miao J, McHugh SM, Butty VL, Whittaker CA, Moore CL, Bloom JD, Lin YS, Shoulders MD. Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones. Plos Biology. 16: e3000008. PMID 30222731 DOI: 10.1371/Journal.Pbio.3000008 |
0.783 |
|
| 2018 |
Phillips AM, Doud MB, Gonzalez LO, Butty VL, Lin YS, Bloom JD, Shoulders MD. Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin. Elife. 7. PMID 30188321 DOI: 10.7554/Elife.38795 |
0.718 |
|
| 2018 |
Moore CL, Papa LJ, Shoulders MD. A Processive Protein Chimera Introduces Mutations Across Defined DNA Regions in vivo. Journal of the American Chemical Society. PMID 29991261 DOI: 10.1021/Jacs.8B04001 |
0.786 |
|
| 2018 |
Wong MY, Doan ND, DiChiara AS, Papa LJ, Cheah JH, Soule CK, Watson N, Hulleman JD, Shoulders MD. High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production. Biochemistry. PMID 29676157 DOI: 10.1021/Acs.Biochem.8B00378 |
0.782 |
|
| 2018 |
Cole KS, Grandjean JMD, Chen K, Witt CH, O'Day J, Shoulders MD, Wiseman RL, Weerapana E. Characterization of an A-Site Selective Protein Disulfide Isomerase A1 Inhibitor. Biochemistry. PMID 29521097 DOI: 10.1021/Acs.Biochem.8B00178 |
0.796 |
|
| 2018 |
Richardson CER, Cunden LS, Butty VL, Nolan EM, Lippard SJ, Shoulders MD. A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency. Journal of the American Chemical Society. PMID 29334734 DOI: 10.1021/Jacs.7B12897 |
0.412 |
|
| 2018 |
Phillips AM, Doud MB, Gonzalez LO, Butty VL, Lin Y, Bloom JD, Shoulders MD. Author response: Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin Elife. DOI: 10.7554/Elife.38795.037 |
0.679 |
|
| 2017 |
Phillips AM, Gonzalez LO, Nekongo EE, Ponomarenko AI, McHugh SM, Butty VL, Levine SS, Lin YS, Mirny LA, Shoulders MD. Host proteostasis modulates influenza evolution. Elife. 6. PMID 28949290 DOI: 10.7554/Elife.28652 |
0.791 |
|
| 2017 |
Wong MY, DiChiara AS, Suen PH, Chen K, Doan ND, Shoulders MD. Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response. Current Topics in Microbiology and Immunology. PMID 28929194 DOI: 10.1007/82_2017_56 |
0.799 |
|
| 2017 |
Phillips AM, Gonzalez LO, Nekongo EE, Ponomarenko AI, McHugh SM, Butty VL, Levine SS, Lin Y, Mirny LA, Shoulders MD. Author response: Host proteostasis modulates influenza evolution Elife. DOI: 10.7554/Elife.28652.022 |
0.768 |
|
| 2017 |
Wong MY, DiChiara AS, Suen PH, Chen K, Doan ND, Shoulders MD. Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response Current Topics in Microbiology and Immunology. 1-25. DOI: 10.1007/82_2017_56 |
0.788 |
|
| 2016 |
Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A. Multidimensional chemical control of CRISPR-Cas9. Nature Chemical Biology. PMID 27820801 DOI: 10.1038/Nchembio.2224 |
0.611 |
|
| 2016 |
DiChiara AS, Taylor RJ, Wong MY, Doan ND, Del Rosario AM, Shoulders MD. Mapping and Exploring the Collagen-I Proteostasis Network. Acs Chemical Biology. PMID 26848503 DOI: 10.1021/Acschembio.5B01083 |
0.804 |
|
| 2015 |
Phillips AM, Shoulders MD. The Path of Least Resistance: Mechanisms to Reduce Influenza's Sensitivity to Oseltamivir. Journal of Molecular Biology. PMID 26748011 DOI: 10.1016/J.Jmb.2015.12.019 |
0.659 |
|
| 2015 |
Moore CL, Dewal MB, Nekongo EE, Santiago S, Lu NB, Levine SS, Shoulders MD. Transportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1. Acs Chemical Biology. PMID 26502114 DOI: 10.1021/Acschembio.5B00740 |
0.79 |
|
| 2015 |
Dewal MB, DiChiara AS, Antonopoulos A, Taylor RJ, Harmon CJ, Haslam SM, Dell A, Shoulders MD. XBP1s Links the Unfolded Protein Response to the Molecular Architecture of Mature N-Glycans. Chemistry & Biology. 22: 1301-12. PMID 26496683 DOI: 10.1016/J.Chembiol.2015.09.006 |
0.794 |
|
| 2015 |
Choudhary A, Kamer KJ, Shoulders MD, Raines RT. 4-ketoproline: An electrophilic proline analog for bioconjugation. Biopolymers. 104: 110-5. PMID 25656588 DOI: 10.1002/Bip.22620 |
0.626 |
|
| 2015 |
Genereux JC, Qu S, Zhou M, Ryno LM, Wang S, Shoulders MD, Kaufman RJ, Lasmézas CI, Kelly JW, Wiseman RL. Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis. The Embo Journal. 34: 4-19. PMID 25361606 DOI: 10.15252/Embj.201488896 |
0.811 |
|
| 2015 |
Phillips A, Nekongo E, Shoulders M. Hijacking the Host Cell's Protein Homeostasis Network to Potentiate Influenza Evolution The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.713.4 |
0.803 |
|
| 2014 |
Chen JJ, Genereux JC, Qu S, Hulleman JD, Shoulders MD, Wiseman RL. ATF6 activation reduces the secretion and extracellular aggregation of destabilized variants of an amyloidogenic protein. Chemistry & Biology. 21: 1564-74. PMID 25444553 DOI: 10.1016/J.Chembiol.2014.09.009 |
0.806 |
|
| 2014 |
Ryno LM, Genereux JC, Naito T, Morimoto RI, Powers ET, Shoulders MD, Wiseman RL. Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1. Acs Chemical Biology. 9: 1273-83. PMID 24689980 DOI: 10.1021/Cb500062N |
0.798 |
|
| 2013 |
Shoulders MD, Ryno LM, Cooley CB, Kelly JW, Wiseman RL. Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells. Journal of the American Chemical Society. 135: 8129-32. PMID 23682758 DOI: 10.1021/Ja402756P |
0.772 |
|
| 2013 |
Shoulders MD, Ryno LM, Genereux JC, Moresco JJ, Tu PG, Wu C, Yates JR, Su AI, Kelly JW, Wiseman RL. Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments. Cell Reports. 3: 1279-92. PMID 23583182 DOI: 10.1016/J.Celrep.2013.03.024 |
0.806 |
|
| 2012 |
Krow GR, Shoulders MD, Edupuganti R, Gandla D, Yu F, Sonnet PE, Sender M, Choudhary A, DeBrosse C, Ross CW, Carroll P, Raines RT. Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics. The Journal of Organic Chemistry. 77: 5331-44. PMID 22607128 DOI: 10.1021/Jo300700A |
0.588 |
|
| 2011 |
Krow GR, Edupuganti R, Gandla D, Yu F, Sender M, Sonnet PE, Zdilla MJ, DeBrosse C, Cannon KC, Ross CW, Choudhary A, Shoulders MD, Raines RT. Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines. The Journal of Organic Chemistry. 76: 3626-34. PMID 21500838 DOI: 10.1021/Jo200117P |
0.586 |
|
| 2011 |
Shoulders MD, Raines RT. Interstrand dipole-dipole interactions can stabilize the collagen triple helix. The Journal of Biological Chemistry. 286: 22905-12. PMID 21482820 DOI: 10.1074/Jbc.M110.199984 |
0.493 |
|
| 2010 |
Krow GR, Liu N, Sender M, Lin G, Centafont R, Sonnet PE, DeBrosse C, Ross CW, Carroll PJ, Shoulders MD, Raines RT. Oligomers of a 5-carboxy-methanopyrrolidine β-amino acid. A search for order. Organic Letters. 12: 5438-41. PMID 21043445 DOI: 10.1021/Ol1022917 |
0.447 |
|
| 2010 |
Shoulders MD, Kotch FW, Choudhary A, Guzei IA, Raines RT. The aberrance of the 4S diastereomer of 4-hydroxyproline. Journal of the American Chemical Society. 132: 10857-65. PMID 20681719 DOI: 10.1021/Ja103082Y |
0.772 |
|
| 2010 |
Shoulders MD, Satyshur KA, Forest KT, Raines RT. Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proceedings of the National Academy of Sciences of the United States of America. 107: 559-64. PMID 20080719 DOI: 10.1073/Pnas.0909592107 |
0.483 |
|
| 2009 |
Shoulders MD, Kamer KJ, Raines RT. Origin of the stability conferred upon collagen by fluorination. Bioorganic & Medicinal Chemistry Letters. 19: 3859-62. PMID 19423349 DOI: 10.1016/J.Bmcl.2009.03.168 |
0.455 |
|
| 2009 |
Shoulders MD, Raines RT. Modulating collagen triple-helix stability with 4-chloro, 4-fluoro, and 4-methylprolines. Advances in Experimental Medicine and Biology. 611: 251-2. PMID 19400182 DOI: 10.1007/978-0-387-73657-0_115 |
0.478 |
|
| 2009 |
Shoulders MD, Raines RT. Collagen structure and stability. Annual Review of Biochemistry. 78: 929-58. PMID 19344236 DOI: 10.1146/Annurev.Biochem.77.032207.120833 |
0.513 |
|
| 2008 |
Shoulders MD, Guzei IA, Raines RT. 4-chloroprolines: synthesis, conformational analysis, and effect on the collagen triple helix. Biopolymers. 89: 443-54. PMID 17937398 DOI: 10.1002/Bip.20864 |
0.492 |
|
| 2006 |
Shoulders MD, Hodges JA, Raines RT. Reciprocity of steric and stereoelectronic effects in the collagen triple helix. Journal of the American Chemical Society. 128: 8112-3. PMID 16787056 DOI: 10.1021/Ja061793D |
0.647 |
|
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