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Jason C. Kwan - Publications

Affiliations: 
2005-2010 University of Florida, Gainesville, Gainesville, FL, United States 
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Uppal S, Metz JL, Xavier RKM, Nepal KK, Xu D, Wang G, Kwan JC. Uncovering Lasonolide A Biosynthesis Using Genome-Resolved Metagenomics. Mbio. e0152422. PMID 36125273 DOI: 10.1128/mbio.01524-22  0.342
2021 Liang X, Chen QY, Seabra GM, Matthew S, Kwan JC, Li C, Paul VJ, Luesch H. Bifunctional Doscadenamides Activate Quorum Sensing in Gram-Negative Bacteria and Synergize with TRAIL to Induce Apoptosis in Cancer Cells. Journal of Natural Products. PMID 33480689 DOI: 10.1021/acs.jnatprod.0c01003  0.764
2020 Waterworth SC, Flórez LV, Rees ER, Hertweck C, Kaltenpoth M, Kwan JC. Horizontal Gene Transfer to a Defensive Symbiont with a Reduced Genome in a Multipartite Beetle Microbiome. Mbio. 11. PMID 32098813 DOI: 10.1128/Mbio.02430-19  0.368
2019 Liang X, Matthew S, Chen QY, Kwan JC, Paul VJ, Luesch H. Discovery and Total Synthesis of Doscadenamide A: A Quorum Sensing Signaling Molecule from a Marine Cyanobacterium. Organic Letters. PMID 31414826 DOI: 10.1021/Acs.Orglett.9B02525  0.759
2019 Acharya D, Miller I, Cui Y, Braun DR, Berres ME, Styles MJ, Li L, Kwan J, Rajski SR, Blackwell HE, Bugni TS. Omics Technologies to Understand Activation of a Biosynthetic Gene Cluster in Micromonospora sp. WMMB235: Deciphering Keyicin Biosynthesis. Acs Chemical Biology. PMID 31120241 DOI: 10.1021/Acschembio.9B00223  0.549
2019 Miller IJ, Rees ER, Ross J, Miller I, Baxa J, Lopera J, Kerby RL, Rey FE, Kwan JC. Autometa: automated extraction of microbial genomes from individual shotgun metagenomes. Nucleic Acids Research. PMID 30838416 DOI: 10.1093/Nar/Gkz148  0.764
2018 Seal BS, Drider D, Oakley BB, Brüssow H, Bikard D, Rich JO, Miller S, Devillard E, Kwan J, Bertin G, Reeves S, Swift SM, Raicek M, Gay CG. Microbial-derived products as potential new antimicrobials. Veterinary Research. 49: 66. PMID 30060765 DOI: 10.1186/S13567-018-0563-5  0.355
2018 Al-Awadhi FH, Gao B, Rezaei MA, Kwan JC, Li C, Ye T, Paul VJ, Luesch H. Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium. Journal of Medicinal Chemistry. PMID 30015488 DOI: 10.1021/Acs.Jmedchem.8B00885  0.773
2018 Flórez LV, Scherlach K, Miller IJ, Rodrigues A, Kwan JC, Hertweck C, Kaltenpoth M. An antifungal polyketide associated with horizontally acquired genes supports symbiont-mediated defense in Lagria villosa beetles. Nature Communications. 9: 2478. PMID 29946103 DOI: 10.1038/S41467-018-04955-6  0.563
2018 Smith TE, Pond CD, Pierce E, Harmer ZP, Kwan J, Zachariah MM, Harper MK, Wyche TP, Matainaho TK, Bugni TS, Barrows LR, Ireland CM, Schmidt EW. Accessing chemical diversity from the uncultivated symbionts of small marine animals. Nature Chemical Biology. PMID 29291350 DOI: 10.1038/Nchembio.2537  0.355
2017 Lopera J, Miller IJ, McPhail KL, Kwan JC. Increased Biosynthetic Gene Dosage in a Genome-Reduced Defensive Bacterial Symbiont. Msystems. 2. PMID 29181447 DOI: 10.1128/mSystems.00096-17  0.789
2017 Torres JP, Tianero MD, Robes JMD, Kwan JC, Biggs JS, Concepcion GP, Olivera BM, Haygood MG, Schmidt EW. Stenotrophomonas-like bacteria are widespread symbionts in cone snail venom ducts. Applied and Environmental Microbiology. PMID 28986377 DOI: 10.1128/Aem.01418-17  0.367
2017 Miller IJ, Chevrette MG, Kwan JC. Interpreting Microbial Biosynthesis in the Genomic Age: Biological and Practical Considerations. Marine Drugs. 15. PMID 28587290 DOI: 10.3390/Md15060165  0.575
2016 Miller IJ, Lopera JG, Montgomery K, Rose W, Kwan JC. A comparative metagenomics approach to marine natural product drug discovery in Hippospongia lachne. Planta Medica. 81: S1-S381. PMID 27976358 DOI: 10.1055/S-0036-1596166  0.752
2016 Miller IJ, Lopera JG, Montgomery K, Puglisi M, Rose W, Kwan JC. Deconvolution of complete microbial genomes from shotgun metagenomes. Planta Medica. 81: S1-S381. PMID 27976331 DOI: 10.1055/S-0036-1596111  0.759
2016 Miller IJ, Lopera J, Miller I, Montgomery K, Puglisi M, Kirby R, Rose W, Rey F, Kwan JC. Autometa: Automated extraction of microbial genomes from metagenomes. Planta Medica. 81: S1-S381. PMID 27976278 DOI: 10.1055/S-0036-1597077  0.755
2016 Miller IJ, Weyna TR, Fong SS, Lim-Fong GE, Kwan JC. Single sample resolution of rare microbial dark matter in a marine invertebrate metagenome. Scientific Reports. 6: 34362. PMID 27681823 DOI: 10.1038/Srep34362  0.574
2016 Miller IJ, Vanee N, Fong SS, Lim-Fong GE, Kwan JC. Lack of overt genome reduction in the bryostatin-producing bryozoan symbiont, "Candidatus Endobugula sertula". Applied and Environmental Microbiology. PMID 27590822 DOI: 10.1128/Aem.01800-16  0.583
2015 Tianero MD, Kwan JC, Wyche TP, Presson AP, Koch M, Barrows LR, Bugni TS, Schmidt EW. Species specificity of symbiosis and secondary metabolism in ascidians. The Isme Journal. 9: 615-28. PMID 25171330 DOI: 10.1038/Ismej.2014.152  0.309
2015 Nelson A, Nguyen T, Ferguson K, Sears J, Tanouye U, Carlson S, Weyna T, Kwan J, Murphy B, Puglisi M. Adaptability of subtropical algae to local microbial populations Planta Medica. 81. DOI: 10.1055/S-0035-1556268  0.509
2015 Weyna T, Barkei J, Miller I, McPhail K, Kwan J. The mandelalides are produced by a symbiont in the phylum Verrucomicrobia in the tunicate Lissoclinum sp. Planta Medica. 81. DOI: 10.1055/S-0035-1556230  0.612
2015 Miller I, Weyna T, Fong S, Lim-Fong G, Kwan J. Single shot deconvolution of the symbiotic Bugula neritina metagenome Planta Medica. 81. DOI: 10.1055/S-0035-1556207  0.496
2015 Miller I, Weyna T, Mlot C, Fong S, McPhail K, Lim-Fong G, Kwan J. Integrated de novo metagenomics and metatranscriptomics to study natural products and microbial ecology in situ Planta Medica. 81. DOI: 10.1055/S-0035-1556116  0.57
2014 Kim B, Park H, Salvador LA, Serrano PE, Kwan JC, Zeller SL, Chen QY, Ryu S, Liu Y, Byeon S, Luesch H, Hong J. Evaluation of class I HDAC isoform selectivity of largazole analogues. Bioorganic & Medicinal Chemistry Letters. 24: 3728-31. PMID 25070421 DOI: 10.1016/J.Bmcl.2014.07.006  0.733
2014 Kwan JC, Tianero MD, Donia MS, Wyche TP, Bugni TS, Schmidt EW. Host control of symbiont natural product chemistry in cryptic populations of the tunicate Lissoclinum patella. Plos One. 9: e95850. PMID 24788869 DOI: 10.1371/Journal.Pone.0095850  0.384
2014 Kwan JC, Liu Y, Ratnayake R, Hatano R, Kuribara A, Morimoto C, Ohnuma K, Paul VJ, Ye T, Luesch H. Grassypeptolides as natural inhibitors of dipeptidyl peptidase 8 and T-cell activation. Chembiochem : a European Journal of Chemical Biology. 15: 799-804. PMID 24591193 DOI: 10.1002/Cbic.201300762  0.778
2014 Miller I, Weyna T, Mlot C, Fong S, McPhail K, Lim-Fong G, Kwan J. Natural products in complex microbiomes – Assembling multiple bacterial genomes directly through shotgun metagenomics Planta Medica. 80. DOI: 10.1055/S-0034-1382362  0.582
2013 Kwan JC, Schmidt EW. Bacterial endosymbiosis in a chordate host: long-term co-evolution and conservation of secondary metabolism. Plos One. 8: e80822. PMID 24324632 DOI: 10.1371/Journal.Pone.0080822  0.358
2013 Lin Z, Torres JP, Ammon MA, Marett L, Teichert RW, Reilly CA, Kwan JC, Hughen RW, Flores M, Tianero MD, Peraud O, Cox JE, Light AR, Villaraza AJ, Haygood MG, et al. A bacterial source for mollusk pyrone polyketides. Chemistry & Biology. 20: 73-81. PMID 23352141 DOI: 10.1016/J.Chembiol.2012.10.019  0.357
2012 Kwan JC, Donia MS, Han AW, Hirose E, Haygood MG, Schmidt EW. Genome streamlining and chemical defense in a coral reef symbiosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 20655-60. PMID 23185008 DOI: 10.1073/Pnas.1213820109  0.389
2012 Hou Y, Tianero MD, Kwan JC, Wyche TP, Michel CR, Ellis GA, Vazquez-Rivera E, Braun DR, Rose WE, Schmidt EW, Bugni TS. Structure and biosynthesis of the antibiotic bottromycin D. Organic Letters. 14: 5050-3. PMID 22984777 DOI: 10.1021/Ol3022758  0.336
2011 Kwan JC, Meickle T, Ladwa D, Teplitski M, Paul V, Luesch H. Lyngbyoic acid, a "tagged" fatty acid from a marine cyanobacterium, disrupts quorum sensing in Pseudomonas aeruginosa Molecular Biosystems. 7: 1205-1216. PMID 21258753 DOI: 10.1039/C0Mb00180E  0.667
2011 Akindele AJ, Eksioglu EA, Kwan JC, Adeyemi OO, Liu C, Luesch H, James MO. Biological effects of Byrsocarpus coccineus in vitro. Pharmaceutical Biology. 49: 152-60. PMID 21110733 DOI: 10.3109/13880209.2010.504967  0.522
2010 Kwan JC, Ratnayake R, Abboud KA, Paul VJ, Luesch H. Grassypeptolides A-C, cytotoxic bis-thiazoline containing marine cyclodepsipeptides. The Journal of Organic Chemistry. 75: 8012-23. PMID 21047144 DOI: 10.1021/Jo1013564  0.77
2010 Kwan JC, Luesch H. Weapons in disguise-Activating mechanisms and protecting group chemistry in nature Chemistry - a European Journal. 16: 13020-13029. PMID 20931575 DOI: 10.1002/Chem.201001562  0.602
2010 Liu Y, Salvador LA, Byeon S, Ying Y, Kwan JC, Law BK, Hong J, Luesch H. Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 335: 351-61. PMID 20739454 DOI: 10.1124/Jpet.110.172387  0.763
2010 Kwan JC, Teplitski M, Gunasekera SP, Paul VJ, Luesch H. Isolation and biological evaluation of 8-epi-malyngamide C from the Floridian marine cyanobacterium Lyngbya majuscula. Journal of Natural Products. 73: 463-6. PMID 20166701 DOI: 10.1021/Np900614N  0.664
2010 Gunasekera SP, Miller MW, Kwan JC, Luesch H, Paul VJ. Molassamide, a depsipeptide serine protease inhibitor from the marine cyanobacterium Dichothrix utahensis. Journal of Natural Products. 73: 459-62. PMID 20020755 DOI: 10.1021/Np900603F  0.694
2009 Kwan JC, Taori K, Paul VJ, Luesch H. Lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena. Marine Drugs. 7: 528-38. PMID 20098596 DOI: 10.3390/Md7040528  0.754
2009 Kwan JC, Eksioglu EA, Liu C, Paul VJ, Luesch H. Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. Journal of Medicinal Chemistry. 52: 5732-47. PMID 19715320 DOI: 10.1021/Jm9009394  0.681
2008 Kwan JC, Rocca JR, Abboud KA, Paul VJ, Luesch H. Total structure determination of grassypeptolide, a new marine cyanobacterial cytotoxin. Organic Letters. 10: 789-92. PMID 18220404 DOI: 10.1021/Ol702946D  0.653
2008 Luesch H, Liu Y, Taori K, Kwan J, Matthew S, Paul V. Bioactive natural products from marine cyanobacteria: new structures and modes of action Planta Medica. 74. DOI: 10.1055/S-0028-1083977  0.734
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