Ranjala Ratnayake - Publications

Affiliations: 
2009-2011 University of Florida, Gainesville, Gainesville, FL, United States 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Matthew S, Chen QY, Ratnayake R, Fermaintt CS, Lucena-Agell D, Bonato F, Prota AE, Lim ST, Wang X, Díaz JF, Risinger AL, Paul VJ, Oliva MÁ, Luesch H. Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33619102 DOI: 10.1073/pnas.2021847118  0.88
2021 Grenning AJ, Emmetiere F, Ratnayake R, Schares HAM, Jones KFM, Bevan-Smith E, Luesch H, Harki DA. Function-oriented and modular (+/-)-cis-pseudoguaianolide synthesis: Discovery of new Nrf2 Activators and NF-κB Inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33502811 DOI: 10.1002/chem.202100038  0.88
2020 Lizarme-Salas Y, Ariawan AD, Ratnayake R, Luesch H, Finch A, Hunter L. Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity. Beilstein Journal of Organic Chemistry. 16: 2663-2670. PMID 33178356 DOI: 10.3762/bjoc.16.216  0.88
2020 Jiang G, Zhang P, Ratnayake R, Yang G, Zhang Y, Zuo R, Powell M, Huguet-Tapia JC, Abboud KA, Dang LH, Teplitski M, Paul V, Xiao R, Zaman KAU, Hu Z, et al. Fungal epithiodiketopiperazines carrying α,β-polysulfide bridges from Penecillium steckii YE, and their chemical interconversion. Chembiochem : a European Journal of Chemical Biology. PMID 32816319 DOI: 10.1002/Cbic.202000403  0.88
2020 Paciaroni NG, Norwood VM, Ratnayake R, Luesch H, Huigens RW. Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets. Bioorganic & Medicinal Chemistry. 28: 115546. PMID 32616180 DOI: 10.1016/J.Bmc.2020.115546  0.88
2020 Al-Awadhi FH, Salvador-Reyes LA, Elsadek LA, Ratnayake R, Chen QY, Luesch H. Largazole is a Brain-Penetrant Class I HDAC Inhibitor with Extended Applicability to Glioblastoma and CNS Diseases. Acs Chemical Neuroscience. PMID 32559056 DOI: 10.1021/Acschemneuro.0C00093  0.88
2020 Tamashunas AC, Tocco VJ, Matthews J, Zhang Q, Atanasova KR, Paschall L, Pathak S, Ratnayake R, Stephens AD, Luesch H, Licht JD, Lele TP. High-throughput gene screen reveals modulators of nuclear shape. Molecular Biology of the Cell. mbcE19090520. PMID 32320319 DOI: 10.1091/Mbc.E19-09-0520  0.88
2020 Ratnayake R, Gunasekera SP, Ma JJ, Dang LH, Carney T, Paul VJ, Luesch H. Dolastatin 15 from a Marine Cyanobacterium Suppresses HIF-1α Mediated Cancer Cell Viability and Vascularization. Chembiochem : a European Journal of Chemical Biology. PMID 32237262 DOI: 10.1002/Cbic.202000180  0.88
2020 Norwood VM, Brice-Tutt A, Eans SO, Stacy H, Shi G, Ratnayake R, Rocca JR, Abboud KA, Li C, Luesch H, McLaughlin JP, Huigens Iii RW. Preventing Morphine Seeking Behavior through the Re-engineering of Vincamine's Biological Activity. Journal of Medicinal Chemistry. PMID 31913038 DOI: 10.1021/Acs.Jmedchem.9B01924  0.88
2020 Norwood V, Brice-Tutt AC, Eans SO, Stacy HM, Shi G, Ratnayake R, Rocca JR, Abboud KA, Li C, Luesch H, McLaughlin JP, Huigens RW. Preventing Morphine-SeekingBehavior through the Re-Engineeringof Vincamine’s Biological Activity Journal of Medicinal Chemistry. DOI: 10.1021/Acs.Jmedchem.9B01924.S001  0.88
2020 Liu Q, Liu L, Ratnayake R, Luesch H, Guo Y, Ye T. Nine‐Step Total Synthesis and Biological Evaluation of Rhizonin A Chinese Journal of Chemistry. DOI: 10.1002/Cjoc.202000222  0.88
2019 Liu L, Guo Y, Liu Q, Ratnayake R, Luesch H, Ye T. Total Synthesis of Endolides A and B. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 30: 2279-2284. PMID 34163101 DOI: 10.1055/s-0037-1610736  0.88
2019 Dekan Z, Sianati S, Yousuf A, Sutcliffe KJ, Gillis A, Mallet C, Singh P, Jin AH, Wang AM, Mohammadi SA, Stewart M, Ratnayake R, Fontaine F, Lacey E, Piggott AM, et al. A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31611414 DOI: 10.1073/Pnas.1908662116  0.56
2019 Bousquet MS, Ratnayake R, Pope JL, Chen QY, Zhu F, Chen S, Carney TJ, Gharaibeh RZ, Jobin C, Paul VJ, Luesch H. Seaweed natural products modify the host inflammatory response via Nrf2 signaling and alter colon microbiota composition and gene expression. Free Radical Biology & Medicine. PMID 31536771 DOI: 10.1016/J.Freeradbiomed.2019.09.013  0.88
2019 Liu L, Guo Y, Liu Q, Ratnayake R, Luesch H, Ye T. Total Synthesis of Endolides A and B Synlett. 30: 2279-2284. DOI: 10.1055/S-0037-1610736  0.88
2018 Yan JL, Cheng Y, Chen J, Ratnayake R, Dang LH, Luesch H, Guo Y, Ye T. Total Synthesis of Asperphenins A and B. Organic Letters. PMID 30232896 DOI: 10.1021/Acs.Orglett.8B02652  0.88
2018 Cai W, Ratnayake R, Gerber MH, Chen QY, Yu Y, Derendorf H, Trevino JG, Luesch H. Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model. Investigational New Drugs. PMID 30073464 DOI: 10.1007/S10637-018-0647-0  0.88
2017 Cai W, Salvador-Reyes LA, Zhang W, Chen QY, Matthew S, Ratnayake R, Seo SJ, Dolles S, Gibson DJ, Paul VJ, Luesch H. Apratyramide, a Marine-Derived Peptidic Stimulator of VEGF-A and Other Growth Factors with Potential Application in Wound Healing. Acs Chemical Biology. PMID 29205032 DOI: 10.1021/Acschembio.7B00827  0.88
2017 Kim B, Ratnayake R, Lee H, Shi G, Zeller SL, Li C, Luesch H, Hong J. Synthesis and biological evaluation of largazole zinc-binding group analogs. Bioorganic & Medicinal Chemistry. PMID 28416100 DOI: 10.1016/J.Bmc.2017.03.071  0.88
2017 Paciaroni NG, Ratnayake R, Matthews JH, Norwood VM, Arnold AC, Dang LH, Luesch H, Huigens RW. Back Cover: A Tryptoline Ring‐Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine (Chem. Eur. J. 18/2017) Chemistry: a European Journal. 23: 4463-4463. DOI: 10.1002/Chem.201605731  0.88
2016 Paciaroni N, Ratnayake R, Matthews J, Norwood V, Arnold A, Dang L, Luesch H, Huigens Iii RW. A Tryptoline Ring Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27900785 DOI: 10.1002/Chem.201604795  0.88
2016 Gunasekera SP, Imperial L, Garst C, Ratnayake R, Dang LH, Paul VJ, Luesch H. Caldoramide, a Modified Pentapeptide from the Marine Cyanobacterium Caldora penicillata. Journal of Natural Products. PMID 27380142 DOI: 10.1021/Acs.Jnatprod.6B00203  0.88
2016 Al-Awadhi FH, Ratnayake R, Paul VJ, Luesch H. Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium. Bioorganic & Medicinal Chemistry. PMID 27211244 DOI: 10.1016/J.Bmc.2016.04.062  0.88
2016 Gunasekera SP, Li Y, Ratnayake R, Luo D, Lo J, Reibenspies JH, Xu Z, Clare-Salzler MJ, Ye T, Paul VJ, Luesch H. Discovery, Total Synthesis and Key Structural Elements for the Immunosuppressive Activity of Cocosolide, a Symmetrical Glycosylated Macrolide Dimer from Marine Cyanobacteria. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27139508 DOI: 10.1002/Chem.201600674  0.88
2016 Caropreso V, Darvishi E, Turbyville TJ, Ratnayake R, Grohar PJ, McMahon JB, Woldemichael G. Englerin A inhibits EWS-FLI1 DNA Binding in Ewings Sarcoma Cells. The Journal of Biological Chemistry. PMID 26961871 DOI: 10.1074/Jbc.M115.701375  0.8
2016 Bousquet MS, Ma JJ, Ratnayake R, Havre PA, Yao J, Dang NH, Paul VJ, Carney TJ, Dang LH, Luesch H. Multidimensional Screening Platform for Simultaneously Targeting Oncogenic KRAS and Hypoxia-Inducible Factors Pathways in Colorectal Cancer. Acs Chemical Biology. PMID 26938486 DOI: 10.1021/Acschembio.5B00860  0.88
2016 Vijayasarathy S, Prasad P, Fremlin LJ, Ratnayake R, Salim AA, Khalil Z, Capon RJ. C3 and 2D C3 Marfey's Methods for Amino Acid Analysis in Natural Products. Journal of Natural Products. PMID 26863178 DOI: 10.1021/Acs.Jnatprod.5B01125  0.8
2014 Kwan JC, Liu Y, Ratnayake R, Hatano R, Kuribara A, Morimoto C, Ohnuma K, Paul VJ, Ye T, Luesch H. Grassypeptolides as natural inhibitors of dipeptidyl peptidase 8 and T-cell activation. Chembiochem : a European Journal of Chemical Biology. 15: 799-804. PMID 24591193 DOI: 10.1002/Cbic.201300762  0.8
2013 Ratnayake R, Liu Y, Paul VJ, Luesch H. Cultivated sea lettuce is a multiorgan protector from oxidative and inflammatory stress by enhancing the endogenous antioxidant defense system. Cancer Prevention Research (Philadelphia, Pa.). 6: 989-99. PMID 24005795 DOI: 10.1158/1940-6207.Capr-13-0014  0.8
2013 Sourbier C, Scroggins BT, Ratnayake R, Prince TL, Lee S, Lee MJ, Nagy PL, Lee YH, Trepel JB, Beutler JA, Linehan WM, Neckers L. Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality. Cancer Cell. 23: 228-37. PMID 23352416 DOI: 10.1016/J.Ccr.2012.12.007  0.8
2012 Diyabalanage T, Ratnayake R, Bokesch HR, Ransom TT, Henrich CJ, Beutler JA, McMahon JB, Gustafson KR. Flabelliferins A and B, sesterterpenoids from the South Pacific sponge Carteriospongia flabellifera. Journal of Natural Products. 75: 1490-4. PMID 22834941 DOI: 10.1021/Np3003518  0.8
2012 Akee RK, Ransom T, Ratnayake R, McMahon JB, Beutler JA. Chlorinated englerins with selective inhibition of renal cancer cell growth. Journal of Natural Products. 75: 459-63. PMID 22280462 DOI: 10.1021/Np200905U  0.8
2011 Popplewell WL, Ratnayake R, Wilson JA, Beutler JA, Colburn NH, Henrich CJ, McMahon JB, McKee TC. Grassypeptolides F and G, cyanobacterial peptides from Lyngbya majuscula. Journal of Natural Products. 74: 1686-91. PMID 21806011 DOI: 10.1021/Np2005083  0.8
2011 Diyabalanage T, Ratnayake R, Wilson JA, Henrich CJ, Beutler JA, Colburn NH, McMahon JB, Gustafson KR. Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. Bioorganic & Medicinal Chemistry Letters. 21: 4397-9. PMID 21733691 DOI: 10.1016/J.Bmcl.2011.06.044  0.8
2011 Devkota KP, Ratnayake R, Colburn NH, Wilson JA, Henrich CJ, McMahon JB, Beutler JA. Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius. Journal of Natural Products. 74: 374-7. PMID 21306129 DOI: 10.1021/Np100736Y  0.8
2011 Versiani MA, Diyabalanage T, Ratnayake R, Henrich CJ, Bates SE, McMahon JB, Gustafson KR. Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2. Journal of Natural Products. 74: 262-6. PMID 21275386 DOI: 10.1021/Np100797Y  0.8
2010 Kwan JC, Ratnayake R, Abboud KA, Paul VJ, Luesch H. Grassypeptolides A-C, cytotoxic bis-thiazoline containing marine cyclodepsipeptides. The Journal of Organic Chemistry. 75: 8012-23. PMID 21047144 DOI: 10.1021/Jo1013564  0.8
2010 Matthew S, Ratnayake R, Becerro MA, Ritson-Williams R, Paul VJ, Luesch H. Intramolecular modulation of serine protease inhibitor activity in a marine cyanobacterium with antifeedant properties. Marine Drugs. 8: 1803-16. PMID 20631871 DOI: 10.3390/Md8061803  0.8
2009 Ratnayake R, Covell D, Ransom TT, Gustafson KR, Beutler JA. Englerin A, a selective inhibitor of renal cancer cell growth, from Phyllanthus engleri. Organic Letters. 11: 57-60. PMID 19061394 DOI: 10.1021/Ol802339W  0.8
2008 Ratnayake R, Fremlin LJ, Lacey E, Gill JH, Capon RJ. Acremolides A-D, lipodepsipeptides from an Australian marine-derived fungus, Acremonium sp. Journal of Natural Products. 71: 403-8. PMID 18288804 DOI: 10.1021/Np070589G  0.8
2007 Capon RJ, Stewart M, Ratnayake R, Lacey E, Gill JH. Citromycetins and bilains A-C: new aromatic polyketides and diketopiperazines from Australian marine-derived and terrestrial Penicillium spp. Journal of Natural Products. 70: 1746-52. PMID 17958395 DOI: 10.1021/Np0702483  0.8
2007 Ratnayake R, Lacey E, Tennant S, Gill JH, Capon RJ. Kibdelones: novel anticancer polyketides from a rare Australian actinomycete. Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 1610-9. PMID 17091523 DOI: 10.1002/Chem.200601236  0.8
2006 Ratnayake R, Lacey E, Tennant S, Gill JH, Capon RJ. Isokibdelones: novel heterocyclic polyketides from a Kibdelosporangium sp. Organic Letters. 8: 5267-70. PMID 17078694 DOI: 10.1021/Ol062113E  0.8
2005 Capon RJ, Ratnayake R, Stewart M, Lacey E, Tennant S, Gill JH. Aspergillazines A-E: novel heterocyclic dipeptides from an Australian strain of Aspergillus unilateralis. Organic & Biomolecular Chemistry. 3: 123-9. PMID 15602607 DOI: 10.1039/B413440K  0.8
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