Alexis R. Demonbreun, Ph.D. - Publications

Affiliations: 
2009 University of Chicago, Chicago, IL 
Area:
Cell Biology, Molecular Biology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ramachandran K, Futtner CR, Sommars MA, Quattrocelli M, Omura Y, Fruzyna E, Wang JC, Waldeck NJ, Senagolage MD, Telles CG, Demonbreun AR, Prendergast E, Lai N, Arango D, Bederman IR, et al. Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis. Nature Metabolism. PMID 38337096 DOI: 10.1038/s42255-024-00983-3  0.628
2024 O'Brien JG, Willis AB, Long AM, Kwon JM, Lee G, Li FW, Page PG, Vo AH, Hadhazy M, Spencer MJ, Crosbie RH, Demonbreun AR, McNally EM. The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix. Jci Insight. PMID 38175727 DOI: 10.1172/jci.insight.173246  0.536
2023 Fullenkamp DE, Willis AB, Curtin JL, Amaral AP, Dittloff KT, Harris SI, Chychula IA, Holgren CW, Burridge PW, Russell B, Demonbreun AR, McNally EM. Physiological stress improves stem cell modeling of dystrophic cardiomyopathy. Disease Models & Mechanisms. PMID 38050701 DOI: 10.1242/dmm.050487  0.436
2023 Long AM, Lee G, Demonbreun A, McNally EM. Extracellular matrix contribution to disease progression and dysfunction in myopathy. American Journal of Physiology. Cell Physiology. PMID 37746696 DOI: 10.1152/ajpcell.00182.2023  0.563
2023 O'Brien JG, Willis AB, Long AM, Kwon J, Lee G, Li F, Page PGT, Vo AH, Hadhazy M, Crosbie RH, Demonbreun AR, McNally EM. The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix. Biorxiv : the Preprint Server For Biology. PMID 37425960 DOI: 10.1101/2023.06.29.547098  0.529
2023 Waters EA, Haney CR, Vaught LA, McNally EM, Demonbreun AR. New semi-automated tool for the quantitation of MR imaging to estimate in vivo muscle disease severity in mice. Biorxiv : the Preprint Server For Biology. PMID 37293050 DOI: 10.1101/2023.05.23.541310  0.581
2022 Wintzinger M, Miz K, York A, Demonbreun AR, Molkentin JD, McNally EM, Quattrocelli M. Effects of Glucocorticoids in Murine Models of Duchenne and Limb-Girdle Muscular Dystrophy. Methods in Molecular Biology (Clifton, N.J.). 2587: 467-478. PMID 36401044 DOI: 10.1007/978-1-0716-2772-3_24  0.584
2022 Demonbreun AR, Bogdanovic E, Vaught LA, Reiser NL, Fallon KS, Long AM, Oosterbaan CC, Hadhazy M, Page PG, Joseph PRB, Cowen G, Telenson AM, Khatri A, Sadleir KR, Vassar R, et al. A conserved annexin A6-mediated membrane repair mechanism in muscle, heart, and nerve. Jci Insight. 7. PMID 35866481 DOI: 10.1172/jci.insight.158107  0.558
2022 Sancilio A, Schrock JM, Demonbreun AR, D'Aquila RT, Mustanski B, Vaught LA, Reiser NL, Velez MP, Hsieh RR, Ryan DT, Saber R, McNally EM, McDade TW. COVID-19 symptom severity predicts neutralizing antibody activity in a community-based serological study. Scientific Reports. 12: 12269. PMID 35851303 DOI: 10.1038/s41598-022-15791-6  0.393
2022 McDade TW, Sancilio A, D'Aquila R, Mustanski B, Vaught LA, Reiser NL, Velez ME, Hsieh RR, Ryan DT, Saber R, McNally EM, Demonbreun AR. Low Levels of Neutralizing Antibodies After Natural Infection With Severe Acute Respiratory Syndrome Coronavirus 2 in a Community-Based Serological Study. Open Forum Infectious Diseases. 9: ofac055. PMID 35252468 DOI: 10.1093/ofid/ofac055  0.377
2022 Simons LM, Lorenzo-Redondo R, Gibson M, Kinch SL, Vandervaart JP, Reiser NL, Eren M, Lux E, McNally EM, Tambur AR, Vaughan DE, Bachta KER, Demonbreun AR, Satchell KJF, Achenbach CJ, et al. Assessment of Virological Contributions to COVID-19 Outcomes in a Longitudinal Cohort of Hospitalized Adults. Open Forum Infectious Diseases. 9: ofac027. PMID 35198645 DOI: 10.1093/ofid/ofac027  0.364
2021 Demonbreun AR, Velez MP, Saber R, Ryan DT, Sancilio A, McDade TW, McNally EM. mRNA intramuscular vaccination produces a robust IgG antibody response in advanced neuromuscular disease. Neuromuscular Disorders : Nmd. 32: 33-35. PMID 34920929 DOI: 10.1016/j.nmd.2021.11.006  0.451
2021 Mustanski B, Saber R, Ryan DT, Benbow N, Madkins K, Hayford C, Newcomb ME, Schrock JM, Vaught LA, Reiser NL, Velez MP, Hsieh RR, Demonbreun AR, D'Aquila R, McNally EM, et al. Geographic disparities in COVID-19 case rates are not reflected in seropositivity rates using a neighborhood survey in Chicago. Annals of Epidemiology. PMID 34728335 DOI: 10.1016/j.annepidem.2021.10.006  0.372
2021 McNally EM, Demonbreun AR. Resealing and rebuilding injured muscle. Science (New York, N.Y.). 374: 262-263. PMID 34648349 DOI: 10.1126/science.abm2240  0.612
2021 Demonbreun AR, Fallon KS, Oosterbaan CC, Vaught LA, Reiser NL, Bogdanovic E, Velez MP, Salamone IM, Page PGT, Hadhazy M, Quattrocelli M, Barefield DY, Wood LD, Gonzalez JP, Morris C, et al. Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy. Science Translational Medicine. 13: eabf0376. PMID 34516828 DOI: 10.1126/scitranslmed.abf0376  0.798
2021 McDade TW, Demonbreun AR, Sancilio A, Mustanski B, D'Aquila RT, McNally EM. Durability of antibody response to vaccination and surrogate neutralization of emerging variants based on SARS-CoV-2 exposure history. Scientific Reports. 11: 17325. PMID 34462501 DOI: 10.1038/s41598-021-96879-3  0.398
2021 Barefield DY, Sell JJ, Tahtah I, Kearns SD, McNally EM, Demonbreun AR. Loss of dysferlin or myoferlin results in differential defects in excitation-contraction coupling in mouse skeletal muscle. Scientific Reports. 11: 15865. PMID 34354129 DOI: 10.1038/s41598-021-95378-9  0.6
2021 Sancilio AE, D'Aquila RT, McNally EM, Velez MP, Ison MG, Demonbreun AR, McDade TW. A surrogate virus neutralization test to quantify antibody-mediated inhibition of SARS-CoV-2 in finger stick dried blood spot samples. Scientific Reports. 11: 15321. PMID 34321523 DOI: 10.1038/s41598-021-94653-z  0.387
2021 Schrock JM, Ryan DT, Saber R, Benbow N, Vaught LA, Reiser N, Velez MP, Hsieh R, Newcomb M, Demonbreun AR, Mustanski B, McNally EM, D'Aquila R, McDade TW. Cohabitation With a Known Coronavirus Disease 2019 Case Is Associated With Greater Antibody Concentration and Symptom Severity in a Community-Based Sample of Seropositive Adults. Open Forum Infectious Diseases. 8: ofab244. PMID 34316503 DOI: 10.1093/ofid/ofab244  0.398
2021 Demonbreun AR, Sancilio A, Velez MP, Ryan DT, Saber R, Vaught LA, Reiser NL, Hsieh RR, D'Aquila RT, Mustanski B, McNally EM, McDade TW. Comparison of IgG and neutralizing antibody responses after one or two doses of COVID-19 mRNA vaccine in previously infected and uninfected individuals. Eclinicalmedicine. 38: 101018. PMID 34278286 DOI: 10.1016/j.eclinm.2021.101018  0.387
2021 Demonbreun AR, Sancilio A, Velez ME, Ryan DT, Pesce L, Saber R, Vaught LA, Reiser NL, Hsieh RR, D'Aquila RT, Mustanski B, McDade TW, McNally EM. COVID-19 mRNA vaccination generates greater IgG levels in women compared to men. The Journal of Infectious Diseases. PMID 34117873 DOI: 10.1093/infdis/jiab314  0.367
2021 Schrock JM, Ryan DT, Saber R, Benbow N, Vaught LA, Reiser N, Velez MP, Hsieh R, Newcomb M, Demonbreun AR, Mustanski B, McNally EM, D'Aquila R, McDade TW. Exposure to SARS-CoV-2 within the household is associated with greater symptom severity and stronger antibody responses in a community-based sample of seropositive adults. Medrxiv : the Preprint Server For Health Sciences. PMID 33758903 DOI: 10.1101/2021.03.11.21253421  0.386
2021 Demonbreun AR, McDade TW, Pesce LL, Vaught LA, Reiser NL, Bogdanovic E, Velez MP, Hsieh RR, Simons LM, Saber R, Ryan DT, Ison MG, Hultquist JF, Wilkins JT, D'Aquila RT, et al. Patterns and persistence of SARS-CoV-2 IgG antibodies in Chicago to monitor COVID-19 exposure. Jci Insight. PMID 33755598 DOI: 10.1172/jci.insight.146148  0.384
2020 Demonbreun AR, McDade TW, Pesce L, Vaught LA, Reiser NL, Bogdanovic E, Velez ME, Hsieh RR, Klaisner CN, Simons LM, Saber R, Ryan DT, Ison MG, Hultquist JF, Wilkins JT, et al. Patterns and persistence of SARS-CoV-2 IgG antibodies in a US metropolitan site. Medrxiv : the Preprint Server For Health Sciences. PMID 33236031 DOI: 10.1101/2020.11.17.20233452  0.378
2020 McDade TW, McNally EM, Zelikovich AS, D'Aquila R, Mustanski B, Miller A, Vaught LA, Reiser NL, Bogdanovic E, Fallon KS, Demonbreun AR. High seroprevalence for SARS-CoV-2 among household members of essential workers detected using a dried blood spot assay. Plos One. 15: e0237833. PMID 32797108 DOI: 10.1371/Journal.Pone.0237833  0.447
2019 Quattrocelli M, Zelikovich AS, Jiang Z, Peek CB, Demonbreun AR, Kuntz NL, Barish GD, Haldar SM, Bass J, McNally EM. Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming. Jci Insight. 4. PMID 31852847 DOI: 10.1172/Jci.Insight.132402  0.607
2019 Demonbreun AR, Wyatt EJ, Fallon KS, Oosterbaan CC, Page P, Hadhazy M, Quattrocelli M, Barefield DY, McNally EM. A gene-edited mouse model of Limb-Girdle muscular dystrophy 2C for testing exon skipping. Disease Models & Mechanisms. PMID 31582396 DOI: 10.1242/Dmm.040832  0.595
2019 Demonbreun AR, Fallon KS, Oosterbaan CC, Bogdanovic E, Warner JL, Sell JJ, Page PG, Quattrocelli M, Barefield DY, McNally EM. Recombinant annexin A6 promotes membrane repair and protects against muscle injury. The Journal of Clinical Investigation. PMID 31545299 DOI: 10.1172/Jci128840  0.604
2019 Aubert G, Barefield DY, Demonbreun AR, Ramratnam M, Fallon KS, Warner JL, Rossi AE, Hadhazy M, Makielski JC, McNally EM. Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective. Jacc. Basic to Translational Science. 4: 251-268. PMID 31061927 DOI: 10.1016/J.Jacbts.2018.11.012  0.454
2019 Kim EY, Barefield DY, Vo AH, Gacita AM, Schuster EJ, Wyatt EJ, Davis JL, Dong B, Sun C, Page P, Dellefave-Castillo L, Demonbreun A, Zhang HF, McNally EM. Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes. Jci Insight. PMID 30730308 DOI: 10.1172/Jci.Insight.122686  0.526
2018 Vo AH, Swaggart KA, Woo A, Gao QQ, Demonbreun AR, Fallon KS, Quattrocelli M, Hadhazy M, Page PGT, Chen Z, Eskin A, Squire K, Nelson SF, McNally EM. Dusp6 is a genetic modifier of growth through enhanced ERK activity. Human Molecular Genetics. PMID 30289454 DOI: 10.1093/Hmg/Ddy349  0.789
2018 Wyatt EJ, Demonbreun AR, Kim EY, Puckelwartz MJ, Vo AH, Dellefave-Castillo LM, Gao QQ, Vainzof M, Pavanello RCM, Zatz M, McNally EM. Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers. Jci Insight. 3. PMID 29720576 DOI: 10.1172/Jci.Insight.99357  0.536
2017 Quattrocelli M, Capote J, Ohiri JC, Warner JL, Vo AH, Earley JU, Hadhazy M, Demonbreun AR, Spencer MJ, McNally EM. Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury. Plos Genetics. 13: e1007070. PMID 29065150 DOI: 10.1371/Journal.Pgen.1007070  0.663
2017 Quattrocelli M, Salamone IM, Page P, Warner JL, Demonbreun AR, McNally EM. Intermittent Glucocorticoid Dosing Improves Muscle Repair and Function in Mice with Limb Girdle Muscular Dystrophy. The American Journal of Pathology. PMID 28823869 DOI: 10.1016/J.Ajpath.2017.07.017  0.801
2017 Quattrocelli M, Barefield DY, Warner JL, Vo AH, Hadhazy M, Earley JU, Demonbreun AR, McNally EM. Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy. The Journal of Clinical Investigation. PMID 28481224 DOI: 10.1172/Jci91445  0.656
2017 Demonbreun AR, McNally EM. Muscle cell communication in development and repair. Current Opinion in Pharmacology. 34: 7-14. PMID 28419894 DOI: 10.1016/J.Coph.2017.03.008  0.693
2016 Demonbreun AR, Quattrocelli M, Barefield DY, Allen MV, Swanson KE, McNally EM. An actin-dependent annexin complex mediates plasma membrane repair in muscle. The Journal of Cell Biology. PMID 27298325 DOI: 10.1083/Jcb.201512022  0.658
2016 Demonbreun AR, Allen MV, Warner JL, Barefield DY, Krishnan S, Swanson KE, Earley JU, McNally EM. Enhanced Muscular Dystrophy from Loss of Dysferlin Is Accompanied by Impaired Annexin A6 Translocation after Sarcolemmal Disruption. The American Journal of Pathology. PMID 27070822 DOI: 10.1016/J.Ajpath.2016.02.005  0.606
2016 Demonbreun AR, McNally EM. Plasma Membrane Repair in Health and Disease. Current Topics in Membranes. 77: 67-96. PMID 26781830 DOI: 10.1016/Bs.Ctm.2015.10.006  0.678
2015 Demonbreun AR, McNally EM. DNA Electroporation, Isolation and Imaging of Myofibers. Journal of Visualized Experiments : Jove. e53551. PMID 26780499 DOI: 10.3791/53551  0.583
2015 Demonbreun AR, Biersmith BH, McNally EM. Membrane fusion in muscle development and repair. Seminars in Cell & Developmental Biology. PMID 26537430 DOI: 10.1016/J.Semcdb.2015.10.026  0.697
2015 Gao QQ, Wyatt E, Goldstein JA, LoPresti P, Castillo LM, Gazda A, Petrossian N, Earley JU, Hadhazy M, Barefield DY, Demonbreun AR, Bönnemann C, Wolf M, McNally EM. Reengineering a transmembrane protein to treat muscular dystrophy using exon skipping. The Journal of Clinical Investigation. PMID 26457733 DOI: 10.1172/Jci82768  0.737
2015 Demonbreun AR, Swanson KE, Rossi AE, Deveaux HK, Earley JU, Allen MV, Arya P, Bhattacharyya S, Band H, Pytel P, McNally EM. Eps 15 Homology Domain (EHD)-1 Remodels Transverse Tubules in Skeletal Muscle. Plos One. 10: e0136679. PMID 26325203 DOI: 10.1371/Journal.Pone.0136679  0.653
2015 Lenhart KC, O'Neill TJ, Cheng Z, Dee R, Demonbreun AR, Li J, Xiao X, McNally EM, Mack CP, Taylor JM. GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice. Skeletal Muscle. 5: 27. PMID 26301073 DOI: 10.1186/S13395-015-0054-6  0.646
2015 Lenhart KC, O'Neill TJ, Cheng Z, Dee R, Demonbreun AR, Li J, Xiao X, McNally EM, Mack CP, Taylor JM. GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice Skeletal Muscle. 5. DOI: 10.1186/s13395-015-0054-6  0.547
2014 Swaggart KA, Demonbreun AR, Vo AH, Swanson KE, Kim EY, Fahrenbach JP, Holley-Cuthrell J, Eskin A, Chen Z, Squire K, Heydemann A, Palmer AA, Nelson SF, McNally EM. Annexin A6 modifies muscular dystrophy by mediating sarcolemmal repair. Proceedings of the National Academy of Sciences of the United States of America. 111: 6004-9. PMID 24717843 DOI: 10.1073/Pnas.1324242111  0.759
2014 Demonbreun AR, McNally EM. Dynamin 2 the rescue for centronuclear myopathy. The Journal of Clinical Investigation. 124: 976-8. PMID 24569368 DOI: 10.1172/Jci74434  0.65
2014 Posey AD, Swanson KE, Alvarez MG, Krishnan S, Earley JU, Band H, Pytel P, McNally EM, Demonbreun AR. EHD1 mediates vesicle trafficking required for normal muscle growth and transverse tubule development. Developmental Biology. 387: 179-90. PMID 24440153 DOI: 10.1016/J.Ydbio.2014.01.004  0.803
2014 Demonbreun AR, Rossi AE, Alvarez MG, Swanson KE, Deveaux HK, Earley JU, Hadhazy M, Vohra R, Walter GA, Pytel P, McNally EM. Dysferlin and myoferlin regulate transverse tubule formation and glycerol sensitivity. The American Journal of Pathology. 184: 248-59. PMID 24177035 DOI: 10.1016/J.Ajpath.2013.09.009  0.674
2011 Posey AD, Demonbreun A, McNally EM. Ferlin proteins in myoblast fusion and muscle growth. Current Topics in Developmental Biology. 96: 203-30. PMID 21621072 DOI: 10.1016/B978-0-12-385940-2.00008-5  0.804
2011 Posey AD, Pytel P, Gardikiotes K, Demonbreun AR, Rainey M, George M, Band H, McNally EM. Endocytic recycling proteins EHD1 and EHD2 interact with fer-1-like-5 (Fer1L5) and mediate myoblast fusion. The Journal of Biological Chemistry. 286: 7379-88. PMID 21177873 DOI: 10.1074/Jbc.M110.157222  0.756
2011 Demonbreun AR, Fahrenbach JP, Deveaux K, Earley JU, Pytel P, McNally EM. Impaired muscle growth and response to insulin-like growth factor 1 in dysferlin-mediated muscular dystrophy. Human Molecular Genetics. 20: 779-89. PMID 21127009 DOI: 10.1093/Hmg/Ddq522  0.67
2010 Demonbreun AR, Lapidos KA, Heretis K, Levin S, Dale R, Pytel P, Svensson EC, McNally EM. Myoferlin regulation by NFAT in muscle injury, regeneration and repair. Journal of Cell Science. 123: 2413-22. PMID 20571050 DOI: 10.1242/Jcs.065375  0.67
2010 Demonbreun AR, Posey AD, Heretis K, Swaggart KA, Earley JU, Pytel P, McNally EM. Myoferlin is required for insulin-like growth factor response and muscle growth. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1284-95. PMID 20008164 DOI: 10.1096/Fj.09-136309  0.781
2008 Doherty KR, Demonbreun AR, Wallace GQ, Cave A, Posey AD, Heretis K, Pytel P, McNally EM. The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion. The Journal of Biological Chemistry. 283: 20252-60. PMID 18502764 DOI: 10.1074/Jbc.M802306200  0.752
2007 Heydemann A, Demonbreun A, Hadhazy M, Earley JU, McNally EM. Nuclear sequestration of delta-sarcoglycan disrupts the nuclear localization of lamin A/C and emerin in cardiomyocytes. Human Molecular Genetics. 16: 355-63. PMID 17164264 DOI: 10.1093/Hmg/Ddl453  0.572
2005 Heydemann A, Huber JM, Demonbreun A, Hadhazy M, McNally EM. Genetic background influences muscular dystrophy. Neuromuscular Disorders : Nmd. 15: 601-9. PMID 16084087 DOI: 10.1016/J.Nmd.2005.05.004  0.547
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