George Georgiou - Publications

Biomedical Engineering University of Texas at Austin, Austin, Texas, U.S.A. 
discovery and development of protein therapeutics and applied immunology by capitalizing on state of the art protein engineering, directed evolution and systems biology technologies

175 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lang X, Green MD, Wang W, Yu J, Choi JE, Jiang L, Liao P, Zhou J, Zhang Q, Dow A, Saripalli AL, Kryczek I, Wei S, Szeliga W, Vatan L, ... ... Georgiou G, et al. Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11. Cancer Discovery. PMID 31554642 DOI: 10.1158/2159-8290.CD-19-0338  0.32
2019 Taft JM, Georgeon S, Allen C, Reckel S, DeSautelle J, Hantschel O, Georgiou G, Iverson BL. A Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity. Acs Chemical Biology. PMID 31339688 DOI: 10.1021/acschembio.9b00283  0.48
2019 Lindesmith LC, McDaniel JR, Changela A, Verardi R, Kerr SA, Costantini V, Brewer-Jensen PD, Mallory ML, Voss WN, Boutz DR, Blazeck JJ, Ippolito GC, Vinje J, Kwong PD, Georgiou G, et al. Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination. Immunity. 50: 1530-1541.e8. PMID 31216462 DOI: 10.1016/j.immuni.2019.05.007  0.36
2019 Wang W, Green M, Choi JE, Gijón M, Kennedy PD, Johnson JK, Liao P, Lang X, Kryczek I, Sell A, Xia H, Zhou J, Li G, Li J, Li W, ... ... Georgiou G, et al. CD8 T cells regulate tumour ferroptosis during cancer immunotherapy. Nature. PMID 31043744 DOI: 10.1038/s41586-019-1170-y  0.32
2019 Krebs SJ, Kwon YD, Schramm CA, Law WH, Donofrio G, Zhou KH, Gift S, Dussupt V, Georgiev IS, Schätzle S, McDaniel JR, Lai YT, Sastry M, Zhang B, Jarosinski MC, ... ... Georgiou G, et al. Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity. PMID 30876875 DOI: 10.1016/j.immuni.2019.02.008  0.36
2019 Lee J, Paparoditis P, Horton AP, Frühwirth A, McDaniel JR, Jung J, Boutz DR, Hussein DA, Tanno Y, Pappas L, Ippolito GC, Corti D, Lanzavecchia A, Georgiou G. Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations. Cell Host & Microbe. PMID 30795981 DOI: 10.1016/j.chom.2019.01.010  0.36
2018 Cai D, Zhang L, Li Y, Wei W, Georgiou GK. The Role of Approximate Number System in Different Mathematics Skills Across Grades. Frontiers in Psychology. 9: 1733. PMID 30279672 DOI: 10.3389/fpsyg.2018.01733  0.36
2018 Zhou W, Xia Z, Georgiou GK, Shu H. SThe distinct roles of dorsal and ventral visual systems in naming of Chinese characters. Neuroscience. PMID 30176323 DOI: 10.1016/j.neuroscience.2018.08.024  0.36
2018 Wei W, Guo L, Georgiou GK, Tavouktsoglou A, Deng C. Different Subcomponents of Executive Functioning Predict Different Growth Parameters in Mathematics: Evidence From a 4-Year Longitudinal Study With Chinese Children. Frontiers in Psychology. 9: 1037. PMID 29977222 DOI: 10.3389/fpsyg.2018.01037  0.48
2018 Liu Y, McDaniel JR, Khan S, Campisi P, Propst EJ, Holler T, Grunebaum E, Georgiou G, Ippolito GC, Ehrhardt GRA. Antibodies Encoded by FCRL4-Bearing Memory B Cells Preferentially Recognize Commensal Microbial Antigens. Journal of Immunology (Baltimore, Md. : 1950). PMID 29703863 DOI: 10.4049/jimmunol.1701549  0.36
2018 McDaniel JR, Pero SC, Voss WN, Shukla GS, Sun Y, Schaetzle S, Lee CH, Horton AP, Harlow S, Gollihar J, Ellefson JW, Krag CC, Tanno Y, Sidiropoulos N, Georgiou G, et al. Identification of tumor-reactive B cells and systemic IgG in breast cancer based on clonal frequency in the sentinel lymph node. Cancer Immunology, Immunotherapy : Cii. PMID 29427082 DOI: 10.1007/s00262-018-2123-2  0.4
2018 Wang B, DeKosky BJ, Timm MR, Lee J, Normandin E, Misasi J, Kong R, McDaniel JR, Delidakis G, Leigh KE, Niezold T, Choi CW, Viox EG, Fahad A, Cagigi A, ... ... Georgiou G, et al. Functional interrogation and mining of natively paired human VH:VL antibody repertoires. Nature Biotechnology. PMID 29309060 DOI: 10.1038/nbt.4052  0.44
2017 Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, ... ... Georgiou G, et al. Corrigendum: IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions. Nature Immunology. 18: 1173. PMID 28926542 DOI: 10.1038/ni1017-1173c  0.36
2017 McDaniel JR, Ippolito GC, Georgiou G. Mapping the secrets of the antibody pool. Nature Biotechnology. PMID 28892077 DOI: 10.1038/nbt.3972  0.36
2017 Altani A, Georgiou GK, Deng C, Cho JR, Katopodi K, Wei W, Protopapas A. Is processing of symbols and words influenced by writing system? Evidence from Chinese, Korean, English, and Greek. Journal of Experimental Child Psychology. 164: 117-135. PMID 28810135 DOI: 10.1016/j.jecp.2017.07.006  0.48
2017 Williams LD, Ofek G, Schätzle S, McDaniel JR, Lu X, Nicely NI, Wu L, Lougheed CS, Bradley T, Louder MK, McKee K, Bailer RT, O'Dell S, Georgiev IS, Seaman MS, ... ... Georgiou G, et al. Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Science Immunology. 2. PMID 28783671 DOI: 10.1126/sciimmunol.aal2200  0.36
2017 Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, ... ... Georgiou G, et al. IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions. Nature Immunology. PMID 28604720 DOI: 10.1038/ni.3770  0.36
2016 Li Q, Yi L, Hoi KH, Marek P, Georgiou G, Iverson BL. Profiling Protease Specificity: Combining Yeast ER Sequestration Screening (YESS) with Next Generation Sequencing. Acs Chemical Biology. PMID 27977123 DOI: 10.1021/acschembio.6b00547  0.48
2016 Cui J, Georgiou GK, Zhang Y, Li Y, Shu H, Zhou X. Examining the relationship between rapid automatized naming and arithmetic fluency in Chinese kindergarten children. Journal of Experimental Child Psychology. 154: 146-163. PMID 27883911 DOI: 10.1016/j.jecp.2016.10.008  0.36
2016 Lee J, Boutz DR, Chromikova V, Joyce MG, Vollmers C, Leung K, Horton AP, DeKosky BJ, Lee CH, Lavinder JJ, Murrin EM, Chrysostomou C, Hoi KH, Tsybovsky Y, Thomas PV, ... ... Georgiou G, et al. Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination. Nature Medicine. PMID 27820605 DOI: 10.1038/nm.4224  0.44
2016 Wang B, Kluwe CA, Lungu OI, DeKosky BJ, Kerr SA, Johnson EL, Tanno H, Lee CH, Jung J, Rezigh AB, Carroll SM, Reyes AN, Bentz JR, Villanueva I, Altman AL, ... ... Georgiou G, et al. Corrigendum: Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining. Scientific Reports. 6: 27229. PMID 27282782 DOI: 10.1038/srep27229  0.44
2016 Wang B, Lee CH, Johnson EL, Kluwe CA, Cunningham JC, Tanno H, Crooks RM, Georgiou G, Ellington AD. Discovery of high affinity anti-ricin antibodies by B cell receptor sequencing and by yeast display of combinatorial VH:VL libraries from immunized animals. Mabs. 0. PMID 27224530 DOI: 10.1080/19420862.2016.1190059  1
2016 DeKosky BJ, Lungu OI, Park D, Johnson EL, Charab W, Chrysostomou C, Kuroda D, Ellington AD, Ippolito GC, Gray JJ, Georgiou G. Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114511 DOI: 10.1073/pnas.1525510113  1
2016 McDaniel JR, DeKosky BJ, Tanno H, Ellington AD, Georgiou G. Ultra-high-throughput sequencing of the immune receptor repertoire from millions of lymphocytes. Nature Protocols. 11: 429-42. PMID 26844430 DOI: 10.1038/nprot.2016.024  1
2015 van den Boer M, Georgiou GK, de Jong PF. Naming of short words is (almost) the same as naming of alphanumeric symbols: Evidence from two orthographies. Journal of Experimental Child Psychology. 144: 152-165. PMID 26741859 DOI: 10.1016/j.jecp.2015.11.016  0.48
2015 Georgiou GK, Das JP. What component of executive functions contributes to normal and impaired reading comprehension in young adults? Research in Developmental Disabilities. 49: 118-128. PMID 26704777 DOI: 10.1016/j.ridd.2015.12.001  0.48
2015 Gorman J, Soto C, Yang MM, Davenport TM, Guttman M, Bailer RT, Chambers M, Chuang GY, DeKosky BJ, Doria-Rose NA, Druz A, Ernandes MJ, Georgiev IS, Jarosinski MC, Joyce MG, ... ... Georgiou G, et al. Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nature Structural & Molecular Biology. PMID 26689967 DOI: 10.1038/nsmb.3144  0.36
2015 Georgiou GK, Aro M, Liao CH, Parrila R. Modeling the relationship between rapid automatized naming and literacy skills across languages varying in orthographic consistency. Journal of Experimental Child Psychology. 143: 48-64. PMID 26615467 DOI: 10.1016/j.jecp.2015.10.017  0.48
2015 Quandt EM, Gollihar J, Blount ZD, Ellington AD, Georgiou G, Barrick JE. Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment. Elife. 4. PMID 26465114 DOI: 10.7554/eLife.09696  1
2015 Murzabaev M, Kojima T, Mizoguchi T, Kobayashi I, DeKosky BJ, Georgiou G, Nakano H. Handmade microfluidic device for biochemical applications in emulsion. Journal of Bioscience and Bioengineering. PMID 26386750 DOI: 10.1016/j.jbiosc.2015.08.001  1
2015 Burrage LC, Sun Q, Elsea SH, Jiang MM, Nagamani SC, Frankel AE, Stone E, Alters SE, Johnson DE, Rowlinson SW, Georgiou G, Lee BH. Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency. Human Molecular Genetics. PMID 26358771 DOI: 10.1093/hmg/ddv352  1
2015 Kerr SA, Jackson EL, Lungu OI, Meyer AG, Demogines A, Ellington AD, Georgiou G, Wilke CO, Sawyer SL. Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses. Journal of Virology. 89: 11643-53. PMID 26355089 DOI: 10.1128/JVI.01408-15  1
2015 Wang B, Kluwe CA, Lungu OI, DeKosky BJ, Kerr SA, Johnson EL, Jung J, Rezigh AB, Carroll SM, Reyes AN, Bentz JR, Villanueva I, Altman AL, Davey RA, Ellington AD, ... Georgiou G, et al. Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining. Scientific Reports. 5: 13926. PMID 26355042 DOI: 10.1038/srep13926  1
2015 Cummine J, Chouinard B, Szepesvari E, Georgiou GK. An examination of the rapid automatized naming-reading relationship using functional magnetic resonance imaging. Neuroscience. 305: 49-66. PMID 26235433 DOI: 10.1016/j.neuroscience.2015.07.071  0.48
2015 Yi L, Taft JM, Li Q, Gebhard MC, Georgiou G, Iverson BL. Yeast Endoplasmic Reticulum Sequestration Screening for the Engineering of Proteases from Libraries Expressed in Yeast. Methods in Molecular Biology (Clifton, N.J.). 1319: 81-93. PMID 26060071 DOI: 10.1007/978-1-4939-2748-7_5  0.48
2015 Fanti KA, Panayiotou G, Lazarou C, Michael R, Georgiou G. The better of two evils? Evidence that children exhibiting continuous conduct problems high or low on callous-unemotional traits score on opposite directions on physiological and behavioral measures of fear. Development and Psychopathology. 1-14. PMID 25916948 DOI: 10.1017/S0954579415000371  0.48
2015 Chrysostomou C, Quandt EM, Marshall NM, Stone E, Georgiou G. An alternate pathway of arsenate resistance in E. coli mediated by the glutathione S-transferase GstB. Acs Chemical Biology. 10: 875-82. PMID 25517993 DOI: 10.1021/cb500755j  1
2015 DeKosky BJ, Kojima T, Rodin A, Charab W, Ippolito GC, Ellington AD, Georgiou G. In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire. Nature Medicine. 21: 86-91. PMID 25501908 DOI: 10.1038/nm.3743  1
2015 Liao CH, Deng C, Hamilton J, Lee CS, Wei W, Georgiou GK. The role of rapid naming in reading development and dyslexia in Chinese. Journal of Experimental Child Psychology. 130: 106-22. PMID 25462035 DOI: 10.1016/j.jecp.2014.10.002  0.48
2015 Lavinder JJ, Horton AP, Georgiou G, Ippolito GC. Next-generation sequencing and protein mass spectrometry for the comprehensive analysis of human cellular and serum antibody repertoires. Current Opinion in Chemical Biology. 24: 112-20. PMID 25461729 DOI: 10.1016/j.cbpa.2014.11.007  1
2015 Cai D, Georgiou GK, Wen M, Das JP. The role of planning in different mathematical skills Journal of Cognitive Psychology. DOI: 10.1080/20445911.2015.1103742  0.48
2015 Song S, Georgiou GK, Su M, Hua S. How well do phonological awareness and rapid automatized naming correlate with Chinese reading accuracy and fluency? A meta-analysis Scientific Studies of Reading. 1-25. DOI: 10.1080/10888438.2015.1088543  0.48
2015 Wei W, Georgiou GK, Deng C. Examining the Cross-Lagged Relationships Between RAN and Word Reading in Chinese Scientific Studies of Reading. 19: 446-455. DOI: 10.1080/10888438.2015.1077447  0.48
2015 Ciping D, Silinskas G, Wei W, Georgiou GK. Cross-lagged relationships between home learning environment and academic achievement in Chinese Early Childhood Research Quarterly. 33: 12-20. DOI: 10.1016/j.ecresq.2015.05.001  0.48
2015 Wine Y, Horton AP, Ippolito GC, Georgiou G. Serology in the 21st century: The molecular-level analysis of the serum antibody repertoire Current Opinion in Immunology. 35: 89-97. DOI: 10.1016/j.coi.2015.06.009  1
2014 Kelton W, Mehta N, Charab W, Lee J, Lee CH, Kojima T, Kang TH, Georgiou G. IgGA: a "cross-isotype" engineered human Fc antibody domain that displays both IgG-like and IgA-like effector functions. Chemistry & Biology. 21: 1603-9. PMID 25500223 DOI: 10.1016/j.chembiol.2014.10.017  1
2014 Romain G, Senyukov V, Rey-Villamizar N, Merouane A, Kelton W, Liadi I, Mahendra A, Charab W, Georgiou G, Roysam B, Lee DA, Varadarajan N. Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells. Blood. 124: 3241-9. PMID 25232058 DOI: 10.1182/blood-2014-04-569061  1
2014 Cummine J, Szepesvari E, Chouinard B, Hanif W, Georgiou GK. A functional investigation of RAN letters, digits, and objects: how similar are they? Behavioural Brain Research. 275: 157-65. PMID 25172183 DOI: 10.1016/j.bbr.2014.08.038  0.48
2014 Lavinder JJ, Hoi KH, Reddy ST, Wine Y, Georgiou G. Systematic characterization and comparative analysis of the rabbit immunoglobulin repertoire. Plos One. 9: e101322. PMID 24978027 DOI: 10.1371/journal.pone.0101322  1
2014 Al Dahhan N, Georgiou GK, Hung R, Munoz D, Parrila R, Kirby JR. Eye movements of university students with and without reading difficulties during naming speed tasks. Annals of Dyslexia. 64: 137-50. PMID 24723032 DOI: 10.1007/s11881-013-0090-z  0.48
2014 Boutz DR, Horton AP, Wine Y, Lavinder JJ, Georgiou G, Marcotte EM. Proteomic identification of monoclonal antibodies from serum. Analytical Chemistry. 86: 4758-66. PMID 24684310 DOI: 10.1021/ac4037679  1
2014 Mroczek ES, Ippolito GC, Rogosch T, Hoi KH, Hwangpo TA, Brand MG, Zhuang Y, Liu CR, Schneider DA, Zemlin M, Brown EE, Georgiou G, Schroeder HW. Differences in the composition of the human antibody repertoire by B cell subsets in the blood. Frontiers in Immunology. 5: 96. PMID 24678310 DOI: 10.3389/fimmu.2014.00096  1
2014 Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, ... ... Georgiou G, et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 509: 55-62. PMID 24590074 DOI: 10.1038/nature13036  1
2014 Lavinder JJ, Wine Y, Giesecke C, Ippolito GC, Horton AP, Lungu OI, Hoi KH, DeKosky BJ, Murrin EM, Wirth MM, Ellington AD, Dörner T, Marcotte EM, Boutz DR, Georgiou G. Identification and characterization of the constituent human serum antibodies elicited by vaccination. Proceedings of the National Academy of Sciences of the United States of America. 111: 2259-64. PMID 24469811 DOI: 10.1073/pnas.1317793111  1
2014 Georgiou G, Ippolito GC, Beausang J, Busse CE, Wardemann H, Quake SR. The promise and challenge of high-throughput sequencing of the antibody repertoire. Nature Biotechnology. 32: 158-68. PMID 24441474 DOI: 10.1038/nbt.2782  1
2014 Georgiou GK, Das JP. University Student With Poor Reading Comprehension: The Hidden Cognitive Processing Deficit. Journal of Learning Disabilities. PMID 24395082 DOI: 10.1177/0022219413513924  0.48
2014 Quandt EM, Deatherage DE, Ellington AD, Georgiou G, Barrick JE. Recursive genomewide recombination and sequencing reveals a key refinement step in the evolution of a metabolic innovation in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 111: 2217-22. PMID 24379390 DOI: 10.1073/pnas.1314561111  1
2014 Tredwin CJ, Young AM, Abou Neel EA, Georgiou G, Knowles JC. Hydroxyapatite, fluor-hydroxyapatite and fluorapatite produced via the sol-gel method: dissolution behaviour and biological properties after crystallisation. Journal of Materials Science. Materials in Medicine. 25: 47-53. PMID 24052344 DOI: 10.1007/s10856-013-5050-y  0.36
2014 Georgiou GK, Das JP. Reading comprehension in university students: Relevance of PASS theory of intelligence Journal of Research in Reading. 37: S101-S115. DOI: 10.1111/j.1467-9817.2012.01542.x  0.48
2014 Georgiou GK, Manolitsis G, Tziraki N. Is Intelligence Relevant in Reading "μανα" and in Calculating "3 + 5"? Cognition, Intelligence, and Achievement: a Tribute to J. P. Das. 225-243. DOI: 10.1016/B978-0-12-410388-7.00012-9  0.48
2014 Deng C, Georgiou GK. Establishing Measurement Invariance of the Cognitive Assessment System Across Cultures Cognition, Intelligence, and Achievement: a Tribute to J. P. Das. 137-148. DOI: 10.1016/B978-0-12-410388-7.00008-7  0.48
2014 Georgiou GK, Papadopoulos TC, Kaizer EL. Different RAN components relate to reading at different points in time Reading and Writing. 27: 1379-1394. DOI: 10.1007/s11145-014-9496-1  0.48
2014 Wang H, Wen H, Tian L, You F, Kui H, Georgiou G. Research on motor vehicle travel trip test for low carbon transportation in ITS Recent Patents On Computer Science. 7: 137-149.  0.36
2013 Protopapas A, Altani A, Georgiou GK. Development of serial processing in reading and rapid naming. Journal of Experimental Child Psychology. 116: 914-29. PMID 24077466 DOI: 10.1016/j.jecp.2013.08.004  0.48
2013 Tanios R, Bekdash A, Kassab E, Stone E, Georgiou G, Frankel AE, Abi-Habib RJ. Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells. Leukemia Research. 37: 1565-71. PMID 24018014 DOI: 10.1016/j.leukres.2013.08.007  1
2013 Agnello G, Chang LL, Lamb CM, Georgiou G, Stone EM. Discovery of a substrate selectivity motif in amino acid decarboxylases unveils a taurine biosynthesis pathway in prokaryotes. Acs Chemical Biology. 8: 2264-71. PMID 23972067 DOI: 10.1021/cb400335k  1
2013 Der BS, Kluwe C, Miklos AE, Jacak R, Lyskov S, Gray JJ, Georgiou G, Ellington AD, Kuhlman B. Alternative computational protocols for supercharging protein surfaces for reversible unfolding and retention of stability. Plos One. 8: e64363. PMID 23741319 DOI: 10.1371/journal.pone.0064363  1
2013 Yi L, Gebhard MC, Li Q, Taft JM, Georgiou G, Iverson BL. Engineering of TEV protease variants by yeast ER sequestration screening (YESS) of combinatorial libraries. Proceedings of the National Academy of Sciences of the United States of America. 110: 7229-34. PMID 23589865 DOI: 10.1073/pnas.1215994110  1
2013 Georgiou GK, Tziraki N, Manolitsis G, Fella A. Is rapid automatized naming related to reading and mathematics for the same reason(s)? A follow-up study from kindergarten to Grade 1. Journal of Experimental Child Psychology. 115: 481-96. PMID 23506806 DOI: 10.1016/j.jecp.2013.01.004  0.48
2013 Carroll S, Georgiou G. Antibody-mediates inhibition of human C1s and the classical complement pathway. Immunobiology. 218: 1041-8. PMID 23434433 DOI: 10.1016/j.imbio.2013.01.001  1
2013 Paley O, Agnello G, Cantor J, Yoo TH, Georgiou G, Stone E. GFP reporter screens for the engineering of amino acid degrading enzymes from libraries expressed in bacteria. Methods in Molecular Biology (Clifton, N.J.). 978: 31-44. PMID 23423887 DOI: 10.1007/978-1-62703-293-3_3  1
2013 Georgiou GK, Parrila R, Cui Y, Papadopoulos TC. Why is rapid automatized naming related to reading? Journal of Experimental Child Psychology. 115: 218-25. PMID 23384823 DOI: 10.1016/j.jecp.2012.10.015  0.48
2013 Wine Y, Boutz DR, Lavinder JJ, Miklos AE, Hughes RA, Hoi KH, Jung ST, Horton AP, Murrin EM, Ellington AD, Marcotte EM, Georgiou G. Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response. Proceedings of the National Academy of Sciences of the United States of America. 110: 2993-8. PMID 23382245 DOI: 10.1073/pnas.1213737110  1
2013 DeKosky BJ, Ippolito GC, Deschner RP, Lavinder JJ, Wine Y, Rawlings BM, Varadarajan N, Giesecke C, Dörner T, Andrews SF, Wilson PC, Hunicke-Smith SP, Willson CG, Ellington AD, Georgiou G. High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire. Nature Biotechnology. 31: 166-9. PMID 23334449 DOI: 10.1038/nbt.2492  1
2013 Needham BD, Carroll SM, Giles DK, Georgiou G, Whiteley M, Trent MS. Modulating the innate immune response by combinatorial engineering of endotoxin. Proceedings of the National Academy of Sciences of the United States of America. 110: 1464-9. PMID 23297218 DOI: 10.1073/pnas.1218080110  1
2013 Tredwin CJ, Young AM, Georgiou G, Shin SH, Kim HW, Knowles JC. Hydroxyapatite, fluor-hydroxyapatite and fluorapatite produced via the sol-gel method. Optimisation, characterisation and rheology. Dental Materials : Official Publication of the Academy of Dental Materials. 29: 166-73. PMID 23218445 DOI: 10.1016/  0.36
2013 Mittal J, Yoo TH, Georgiou G, Truskett TM. Structural ensemble of an intrinsically disordered polypeptide. The Journal of Physical Chemistry. B. 117: 118-24. PMID 23205890 DOI: 10.1021/jp308984e  1
2013 Jung ST, Kelton W, Kang TH, Ng DT, Andersen JT, Sandlie I, Sarkar CA, Georgiou G. Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity. Acs Chemical Biology. 8: 368-75. PMID 23030766 DOI: 10.1021/cb300455f  1
2013 Protopapas A, Altani A, Georgiou GK. RAN Backward: A Test of the Visual Scanning Hypothesis Scientific Studies of Reading. 17: 453-461. DOI: 10.1080/10888438.2013.769556  0.48
2012 Chatrchyan S, Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Aguilo E, Bergauer T, Dragicevic M, Erö J, Fabjan C, Friedl M, Frühwirth R, Ghete VM, Hammer J, Hörmann N, ... ... Georgiou G, et al. Observation of sequential Υ suppression in PbPb collisions. Physical Review Letters. 109: 222301. PMID 23368113 DOI: 10.1103/PhysRevLett.109.222301  0.16
2012 Saggy I, Wine Y, Shefet-Carasso L, Nahary L, Georgiou G, Benhar I. Antibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining. Protein Engineering, Design & Selection : Peds. 25: 539-49. PMID 22988130 DOI: 10.1093/protein/gzs060  1
2012 Stone E, Paley O, Hu J, Ekerdt B, Cheung NK, Georgiou G. De novo engineering of a human cystathionine-γ-lyase for systemic (L)-Methionine depletion cancer therapy. Acs Chemical Biology. 7: 1822-9. PMID 22963240 DOI: 10.1021/cb300335j  1
2012 Li W, Cantor JR, Yogesha SD, Yang S, Chantranupong L, Liu JQ, Agnello G, Georgiou G, Stone EM, Zhang Y. Uncoupling intramolecular processing and substrate hydrolysis in the N-terminal nucleophile hydrolase hASRGL1 by circular permutation. Acs Chemical Biology. 7: 1840-7. PMID 22891768 DOI: 10.1021/cb300232n  1
2012 Borrok MJ, Jung ST, Kang TH, Monzingo AF, Georgiou G. Revisiting the role of glycosylation in the structure of human IgG Fc. Acs Chemical Biology. 7: 1596-602. PMID 22747430 DOI: 10.1021/cb300130k  1
2012 Romero PA, Stone E, Lamb C, Chantranupong L, Krause A, Miklos AE, Hughes RA, Fechtel B, Ellington AD, Arnold FH, Georgiou G. SCHEMA-designed variants of human Arginase I and II reveal sequence elements important to stability and catalysis. Acs Synthetic Biology. 1: 221-8. PMID 22737599 DOI: 10.1021/sb300014t  1
2012 Rani M, Bolles M, Donaldson EF, Van Blarcom T, Baric R, Iverson B, Georgiou G. Increased antibody affinity confers broad in vitro protection against escape mutants of severe acute respiratory syndrome coronavirus. Journal of Virology. 86: 9113-21. PMID 22696652 DOI: 10.1128/JVI.00233-12  1
2012 Papadopoulos TC, Georgiou GK, Parrila RK. Low-level deficits in beat perception: neither necessary nor sufficient for explaining developmental dyslexia in a consistent orthography. Research in Developmental Disabilities. 33: 1841-56. PMID 22695074 DOI: 10.1016/j.ridd.2012.04.009  0.48
2012 Skretas G, Makino T, Varadarajan N, Pogson M, Georgiou G. Multi-copy genes that enhance the yield of mammalian G protein-coupled receptors in Escherichia coli. Metabolic Engineering. 14: 591-602. PMID 22609824 DOI: 10.1016/j.ymben.2012.05.001  1
2012 Ippolito GC, Hoi KH, Reddy ST, Carroll SM, Ge X, Rogosch T, Zemlin M, Shultz LD, Ellington AD, Vandenberg CL, Georgiou G. Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse. Plos One. 7: e35497. PMID 22558161 DOI: 10.1371/journal.pone.0035497  1
2012 Miklos AE, Kluwe C, Der BS, Pai S, Sircar A, Hughes RA, Berrondo M, Xu J, Codrea V, Buckley PE, Calm AM, Welsh HS, Warner CR, Zacharko MA, Carney JP, ... ... Georgiou G, et al. Structure-based design of supercharged, highly thermoresistant antibodies. Chemistry & Biology. 19: 449-55. PMID 22520751 DOI: 10.1016/j.chembiol.2012.01.018  1
2012 Georgiou GK, Papadopoulos TC, Zarouna E, Parrila R. Are auditory and visual processing deficits related to developmental dyslexia? Dyslexia (Chichester, England). 18: 110-29. PMID 22419585 DOI: 10.1002/dys.1439  0.48
2012 Georgiou G, Lee SY. Editorial: Michael Shuler's legacy in biochemical engineering. Biotechnology Journal. 7: 314-6. PMID 22383185 DOI: 10.1002/biot.201290012  1
2012 Mauldin JP, Zeinali I, Kleypas K, Woo JH, Blackwood RS, Jo CH, Stone EM, Georgiou G, Frankel AE. Recombinant human arginase toxicity in mice is reduced by citrulline supplementation. Translational Oncology. 5: 26-31. PMID 22348173 DOI: 10.1593/tlo.11262  1
2012 Yoo TH, Pogson M, Iverson BL, Georgiou G. Directed evolution of highly selective proteases by using a novel FACS-based screen that capitalizes on the p53 regulator MDM2. Chembiochem : a European Journal of Chemical Biology. 13: 649-53. PMID 22334509 DOI: 10.1002/cbic.201100718  1
2012 Georgiou GK, Papadopoulos TC, Fella A, Parrila R. Rapid naming speed components and reading development in a consistent orthography. Journal of Experimental Child Psychology. 112: 1-17. PMID 22297121 DOI: 10.1016/j.jecp.2011.11.006  0.48
2012 Cantor JR, Panayiotou V, Agnello G, Georgiou G, Stone EM. Engineering reduced-immunogenicity enzymes for amino acid depletion therapy in cancer. Methods in Enzymology. 502: 291-319. PMID 22208990 DOI: 10.1016/B978-0-12-416039-2.00015-X  1
2012 Stone E, Chantranupong L, Gonzalez C, O'Neal J, Rani M, VanDenBerg C, Georgiou G. Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 158: 171-9. PMID 22001609 DOI: 10.1016/j.jconrel.2011.09.097  1
2012 Agrawal V, Woo JH, Mauldin JP, Jo C, Stone EM, Georgiou G, Frankel AE. Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells. Anti-Cancer Drugs. 23: 51-64. PMID 21955999 DOI: 10.1097/CAD.0b013e32834ae42b  1
2011 Reddy ST, Georgiou G. Systems analysis of adaptive immunity by utilization of high-throughput technologies. Current Opinion in Biotechnology. 22: 584-9. PMID 21570821 DOI: 10.1016/j.copbio.2011.04.015  1
2011 Makino T, Skretas G, Georgiou G. Strain engineering for improved expression of recombinant proteins in bacteria. Microbial Cell Factories. 10: 32. PMID 21569582 DOI: 10.1186/1475-2859-10-32  1
2011 Feeney MA, Veeravalli K, Boyd D, Gon S, Faulkner MJ, Georgiou G, Beckwith J. Repurposing lipoic acid changes electron flow in two important metabolic pathways of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 108: 7991-6. PMID 21521794 DOI: 10.1073/pnas.1105429108  1
2011 Jung ST, Kang TH, Kelton W, Georgiou G. Bypassing glycosylation: engineering aglycosylated full-length IgG antibodies for human therapy. Current Opinion in Biotechnology. 22: 858-67. PMID 21420850 DOI: 10.1016/j.copbio.2011.03.002  1
2011 Qazi O, Rani M, Gnanam AJ, Cullen TW, Stead CM, Kensing H, McCaul K, Ngugi S, Prior JL, Lipka A, Nagy JM, Gregory CW, Judy BM, Harding SV, Titball RW, ... ... Georgiou G, et al. Development of reagents and assays for the detection of pathogenic Burkholderia species. Faraday Discussions. 149: 23-36; discussion 63. PMID 21413172 DOI: 10.1039/c005422b  1
2011 Cantor JR, Stone EM, Georgiou G. Expression and biochemical characterization of the human enzyme N-terminal asparagine amidohydrolase. Biochemistry. 50: 3025-33. PMID 21375249 DOI: 10.1021/bi101832w  1
2011 Cantor JR, Yoo TH, Dixit A, Iverson BL, Forsthuber TG, Georgiou G. Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift. Proceedings of the National Academy of Sciences of the United States of America. 108: 1272-7. PMID 21209329 DOI: 10.1073/pnas.1014739108  1
2011 Veeravalli K, Boyd D, Iverson BL, Beckwith J, Georgiou G. Laboratory evolution of glutathione biosynthesis reveals natural compensatory pathways. Nature Chemical Biology. 7: 101-5. PMID 21186348 DOI: 10.1038/nchembio.499  1
2011 Makino T, Skretas G, Kang TH, Georgiou G. Comprehensive engineering of Escherichia coli for enhanced expression of IgG antibodies Metabolic Engineering. 13: 241-251. PMID 21130896 DOI: 10.1016/j.ymben.2010.11.002  1
2011 Arredondo SA, Georgiou G. The problem of expression of multidisulfide bonded recombinant proteins in E. coli Protein Reviews. 14: 183-215. DOI: 10.1007/978-1-4419-7273-6-9  1
2010 Stone EM, Chantranupong L, Georgiou G. The second-shell metal ligands of human arginase affect coordination of the nucleophile and substrate. Biochemistry. 49: 10582-8. PMID 21053939 DOI: 10.1021/bi101542t  1
2010 Qiu JK, Jung ST, Georgiou G, Hang HY. Enrichment of Escherichia coli spheroplasts displaying scFv antibodies specific for antigens expressed on the human cell surface. Applied Microbiology and Biotechnology. 88: 1385-91. PMID 20878322 DOI: 10.1007/s00253-010-2861-3  1
2010 Reddy ST, Ge X, Miklos AE, Hughes RA, Kang SH, Hoi KH, Chrysostomou C, Hunicke-Smith SP, Iverson BL, Tucker PW, Ellington AD, Georgiou G. Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells. Nature Biotechnology. 28: 965-9. PMID 20802495 DOI: 10.1038/nbt.1673  1
2010 Skretas G, Georgiou G. Simple genetic selection protocol for isolation of overexpressed genes that enhance accumulation of membrane-integrated human G protein-coupled receptors in Escherichia coli Applied and Environmental Microbiology. 76: 5852-5859. PMID 20639362 DOI: 10.1128/AEM.00963-10  1
2010 Jung ST, Kang TH, Georgiou G. Efficient expression and purification of human aglycosylated Fcgamma receptors in Escherichia coli. Biotechnology and Bioengineering. 107: 21-30. PMID 20506277 DOI: 10.1002/bit.22785  1
2010 Mazor Y, Van Blarcom T, Carroll S, Georgiou G. Selection of full-length IgGs by tandem display on filamentous phage particles and Escherichia coli fluorescence-activated cell sorting screening. The Febs Journal. 277: 2291-303. PMID 20423457 DOI: 10.1111/j.1742-4658.2010.07645.x  1
2010 Van Blarcom TJ, Sofer-Podesta C, Ang J, Boyer JL, Crystal RG, Georgiou G. Affinity maturation of an anti-V antigen IgG expressed in situ through adenovirus gene delivery confers enhanced protection against Yersinia pestis challenge. Gene Therapy. 17: 913-21. PMID 20393511 DOI: 10.1038/gt.2010.42  1
2010 Ge X, Mazor Y, Hunicke-Smith SP, Ellington AD, Georgiou G. Rapid construction and characterization of synthetic antibody libraries without DNA amplification. Biotechnology and Bioengineering. 106: 347-57. PMID 20198660 DOI: 10.1002/bit.22712  1
2010 Jung ST, Reddy ST, Kang TH, Borrok MJ, Sandlie I, Tucker PW, Georgiou G. Aglycosylated IgG variants expressed in bacteria that selectively bind FcgammaRI potentiate tumor cell killing by monocyte-dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 604-9. PMID 20080725 DOI: 10.1073/pnas.0908590107  1
2010 Stone EM, Glazer ES, Chantranupong L, Cherukuri P, Breece RM, Tierney DL, Curley SA, Iverson BL, Georgiou G. Replacing Mn(2+) with Co(2+) in human arginase i enhances cytotoxicity toward l-arginine auxotrophic cancer cell lines. Acs Chemical Biology. 5: 333-42. PMID 20050660 DOI: 10.1021/cb900267j  1
2009 Varadarajan N, Pogson M, Georgiou G, Iverson BL. Proteases that can distinguish among different post-translational forms of tyrosine engineered using multicolor flow cytometry. Journal of the American Chemical Society. 131: 18186-90. PMID 19924991 DOI: 10.1021/ja907803k  1
2009 Cantor JR, Stone EM, Chantranupong L, Georgiou G. The human asparaginase-like protein 1 hASRGL1 is an Ntn hydrolase with beta-aspartyl peptidase activity. Biochemistry. 48: 11026-31. PMID 19839645 DOI: 10.1021/bi901397h  1
2009 Skretas G, Carroll S, DeFrees S, Schwartz MF, Johnson KF, Georgiou G. Expression of active human sialyltransferase ST6GalNAcI in Escherichia coli. Microbial Cell Factories. 8: 50. PMID 19788761 DOI: 10.1186/1475-2859-8-50  1
2009 Zhou L, Zhao M, Wolf RZ, Graham DE, Georgiou G. Transcriptional regulation of the Escherichia coli gene rraB, encoding a protein inhibitor of RNase E Journal of Bacteriology. 191: 6665-6674. PMID 19717586 DOI: 10.1128/JB.00344-09  1
2009 Pogson M, Georgiou G, Iverson BL. Engineering next generation proteases. Current Opinion in Biotechnology. 20: 390-7. PMID 19709875 DOI: 10.1016/j.copbio.2009.07.003  1
2009 Arredondo SA, Chen TF, Riggs AF, Gilbert HF, Georgiou G. Role of dimerization in the catalytic properties of the Escherichia coli disulfide isomerase DsbC. The Journal of Biological Chemistry. 284: 23972-9. PMID 19581640 DOI: 10.1074/jbc.M109.010199  0.8
2009 Varadarajan N, Cantor JR, Georgiou G, Iverson BL. Construction and flow cytometric screening of targeted enzyme libraries. Nature Protocols. 4: 893-901. PMID 19478805 DOI: 10.1038/nprot.2009.60  1
2009 Leysath CE, Monzingo AF, Maynard JA, Barnett J, Georgiou G, Iverson BL, Robertus JD. Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen. Journal of Molecular Biology. 387: 680-93. PMID 19361425 DOI: 10.1016/j.jmb.2009.02.003  1
2009 Mazor Y, Van Blarcom T, Iverson BL, Georgiou G. Isolation of full-length IgG antibodies from combinatorial libraries expressed in Escherichia coli. Methods in Molecular Biology (Clifton, N.J.). 525: 217-39, xiv. PMID 19252859 DOI: 10.1007/978-1-59745-554-1_11  1
2009 Seo MJ, Jeong KJ, Leysath CE, Ellington AD, Iverson BL, Georgiou G. Engineering antibody fragments to fold in the absence of disulfide bonds. Protein Science : a Publication of the Protein Society. 18: 259-67. PMID 19177559 DOI: 10.1002/pro.31  1
2009 Eser M, Masip L, Kadokura H, Georgiou G, Beckwith J. Disulfide bond formation by exported glutaredoxin indicates glutathione's presence in the E. coli periplasm. Proceedings of the National Academy of Sciences of the United States of America. 106: 1572-7. PMID 19164554 DOI: 10.1073/pnas.0812596106  1
2009 Skretas G, Georgiou G. Genetic analysis of G protein-coupled receptor expression in Escherichia Coli: Inhibitory role of DnaJ on the membrane integration of the human central cannabinoid receptor Biotechnology and Bioengineering. 102: 357-367. PMID 18828176 DOI: 10.1002/bit.22097  1
2009 Strauch EM, Georgiou G. Mechanistic challenges and engineering applications of protein export in E. coli Systems Biology and Biotechnology of Escherichia Coli. 327-349. DOI: 10.1007/978-1-4020-9394-4_16  1
2008 Mazor Y, Van Blarcom T, Iverson BL, Georgiou G. E-clonal antibodies: selection of full-length IgG antibodies using bacterial periplasmic display. Nature Protocols. 3: 1766-77. PMID 18948976 DOI: 10.1038/nprot.2008.176  1
2008 Skretas G, Georgiou G. Engineering G protein-coupled receptor expression in bacteria Proceedings of the National Academy of Sciences of the United States of America. 105: 14747-14748. PMID 18812517 DOI: 10.1073/pnas.0807741105  1
2008 Arredondo S, Segatori L, Gilbert HF, Georgiou G. De novo design and evolution of artificial disulfide isomerase enzymes analogous to the bacterial DsbC. The Journal of Biological Chemistry. 283: 31469-76. PMID 18782764 DOI: 10.1074/jbc.M803346200  1
2008 Varadarajan N, Georgiou G, Iverson BL. An engineered protease that cleaves specifically after sulfated tyrosine. Angewandte Chemie (International Ed. in English). 47: 7861-3. PMID 18780393 DOI: 10.1002/anie.200800736  1
2008 Link AJ, Skretas G, Strauch EM, Chari NS, Georgiou G. Efficient production of membrane-integrated and detergent-soluble G protein-coupled receptors in Escherichia coli. Protein Science : a Publication of the Protein Society. 17: 1857-63. PMID 18593817 DOI: 10.1110/ps.035980.108  1
2008 Faulkner MJ, Veeravalli K, Gon S, Georgiou G, Beckwith J. Functional plasticity of a peroxidase allows evolution of diverse disulfide-reducing pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 6735-40. PMID 18456836 DOI: 10.1073/pnas.0801986105  1
2008 Varadarajan N, Rodriguez S, Hwang BY, Georgiou G, Iverson BL. Highly active and selective endopeptidases with programmed substrate specificities. Nature Chemical Biology. 4: 290-4. PMID 18391948 DOI: 10.1038/nchembio.80  1
2008 Cobaugh CW, Almagro JC, Pogson M, Iverson B, Georgiou G. Synthetic Antibody Libraries Focused Towards Peptide Ligands Journal of Molecular Biology. 378: 622-633. PMID 18384812 DOI: 10.1016/j.jmb.2008.02.037  1
2008 Li HX, Hwang BY, Laxmikanthan G, Blaber SI, Blaber M, Golubkov PA, Ren P, Iverson BL, Georgiou G. Substrate specificity of human kallikreins 1 and 6 determined by phage display. Protein Science : a Publication of the Protein Society. 17: 664-72. PMID 18359858 DOI: 10.1110/ps.073333208  0.48
2008 Masip L, Klein-Marcuschamer D, Quan S, Bardwell JC, Georgiou G. Laboratory evolution of Escherichia coli thioredoxin for enhanced catalysis of protein oxidation in the periplasm reveals a phylogenetically conserved substrate specificity determinant. The Journal of Biological Chemistry. 283: 840-8. PMID 18003618 DOI: 10.1074/jbc.M705147200  1
2008 Veeravalli K, Faulkner M, Chrysostomou C, Beckwith J, Georgiou G. Investigating the status of oxidative protein folding in escherichia coli missing components of the thiol-redox pathways Aiche Annual Meeting, Conference Proceedings 1
2008 Van Blarcom TJ, Carroll S, Mazor Y, Georgiou G. A comparison of antibodies isolated from immune libraries by two different Anchored Periplasmic Expression (APEx) systems Aiche Annual Meeting, Conference Proceedings 1
2008 Jung ST, Kang TH, Sandlie I, Tucker PW, Georgiou G. Engineering of aglycosylated antibody Fc for selective binding to Fc gamma receptors and effector function Aiche Annual Meeting, Conference Proceedings 1
2007 Strauch EM, Georgiou G. Escherichia coli tatC mutations that suppress defective twin-arginine transporter signal peptides. Journal of Molecular Biology. 374: 283-91. PMID 17936785 DOI: 10.1016/j.jmb.2007.09.050  1
2007 Link AJ, Jeong KJ, Georgiou G. Beyond toothpicks: new methods for isolating mutant bacteria. Nature Reviews. Microbiology. 5: 680-8. PMID 17676054 DOI: 10.1038/nrmicro1715  1
2007 Jung ST, Jeong KJ, Iverson BL, Georgiou G. Binding and enrichment of Escherichia coli spheroplasts expressing inner membrane tethered scFv antibodies on surface immobilized antigens. Biotechnology and Bioengineering. 98: 39-47. PMID 17657772 DOI: 10.1002/bit.21405  1
2007 Jeong KJ, Seo MJ, Iverson BL, Georgiou G. APEx 2-hybrid, a quantitative protein-protein interaction assay for antibody discovery and engineering. Proceedings of the National Academy of Sciences of the United States of America. 104: 8247-52. PMID 17494738 DOI: 10.1073/pnas.0702650104  1
2007 Ribnicky B, Van Blarcom T, Georgiou G. A scFv Antibody Mutant Isolated in a Genetic Screen for Improved Export via the Twin Arginine Transporter Pathway Exhibits Faster Folding Journal of Molecular Biology. 369: 631-639. PMID 17462668 DOI: 10.1016/j.jmb.2007.03.068  1
2007 Rouhier N, Unno H, Bandyopadhyay S, Masip L, Kim SK, Hirasawa M, Gualberto JM, Lattard V, Kusunoki M, Knaff DB, Georgiou G, Hase T, Johnson MK, Jacquot JP. Functional, structural, and spectroscopic characterization of a glutathione-ligated [2Fe-2S] cluster in poplar glutaredoxin C1. Proceedings of the National Academy of Sciences of the United States of America. 104: 7379-84. PMID 17460036 DOI: 10.1073/pnas.0702268104  1
2007 Strauch EM, Georgiou G. A bacterial two-hybrid system based on the twin-arginine transporter pathway of E. coli. Protein Science : a Publication of the Protein Society. 16: 1001-8. PMID 17456749 DOI: 10.1110/ps.062687207  1
2007 Mazor Y, Van Blarcom T, Mabry R, Iverson BL, Georgiou G. Isolation of engineered, full-length antibodies from libraries expressed in Escherichia coli. Nature Biotechnology. 25: 563-5. PMID 17435747 DOI: 10.1038/nbt1296  1
2007 Levy R, Molineux IJ, Iverson BL, Georgiou G. Isolation of trans-acting genes that enhance soluble expression of scFv antibodies in the E. coli cytoplasm by lambda phage display. Journal of Immunological Methods. 321: 164-73. PMID 17328908 DOI: 10.1016/j.jim.2007.01.017  1
2007 Tullman-Ercek D, DeLisa MP, Kawarasaki Y, Iranpour P, Ribnicky B, Palmer T, Georgiou G. Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides. The Journal of Biological Chemistry. 282: 8309-16. PMID 17218314 DOI: 10.1074/jbc.M610507200  0.52
2006 Gao J, Lee K, Zhao M, Qiu J, Zhan X, Saxena A, Moore CJ, Cohen SN, Georgiou G. Differential modulation of E. coli mRNA abundance by inhibitory proteins that alter the composition of the degradosome Molecular Microbiology. 61: 394-406. PMID 16771842 DOI: 10.1111/j.1365-2958.2006.05246.x  1
2006 Masip L, Veeravalli K, Georgiou G. The many faces of glutathione in bacteria. Antioxidants & Redox Signaling. 8: 753-62. PMID 16771667 DOI: 10.1089/ars.2006.8.753  1
2006 Lee PA, Tullman-Ercek D, Georgiou G. The bacterial twin-arginine translocation pathway. Annual Review of Microbiology. 60: 373-95. PMID 16756481 DOI: 10.1146/annurev.micro.60.080805.142212  0.52
2006 Segatori L, Murphy L, Arredondo S, Kadokura H, Gilbert H, Beckwith J, Georgiou G. Conserved role of the linker alpha-helix of the bacterial disulfide isomerase DsbC in the avoidance of misoxidation by DsbB. The Journal of Biological Chemistry. 281: 4911-9. PMID 16280324 DOI: 10.1074/jbc.M505453200  1
2005 Georgiou G, Segatori L. Preparative expression of secreted proteins in bacteria: status report and future prospects. Current Opinion in Biotechnology. 16: 538-45. PMID 16095898 DOI: 10.1016/j.copbio.2005.07.008  1
2004 Zhang M, Monzingo AF, Segatori L, Georgiou G, Robertus JD. Structure of DsbC from Haemophilus influenzae. Acta Crystallographica. Section D, Biological Crystallography. 60: 1512-8. PMID 15333920 DOI: 10.1107/S0907444904014593  1
2004 Segatori L, Paukstelis PJ, Gilbert HF, Georgiou G. Engineered DsbC chimeras catalyze both protein oxidation and disulfide-bond isomerization in Escherichia coli: Reconciling two competing pathways. Proceedings of the National Academy of Sciences of the United States of America. 101: 10018-23. PMID 15220477 DOI: 10.1073/pnas.0403003101  1
2004 Masip L, Pan JL, Haldar S, Penner-Hahn JE, DeLisa MP, Georgiou G, Bardwell JC, Collet JF. An engineered pathway for the formation of protein disulfide bonds. Science (New York, N.Y.). 303: 1185-9. PMID 14976313 DOI: 10.1126/science.1092612  1
2004 Zhan X, Gao J, Jain C, Cieslewicz MJ, Swartz JR, Georgiou G. Genetic analysis of disulfide isomerization in Escherichia coli: expression of DsbC is modulated by RNase E-dependent mRNA processing. Journal of Bacteriology. 186: 654-60. PMID 14729690 DOI: 10.1128/JB.186.3.654-660.2004  1
2003 Monzingo AF, Gao J, Qiu J, Georgiou G, Robertus JD. The X-ray structure of Escherichia coli RraA (MenG), A protein inhibitor of RNA processing. Journal of Molecular Biology. 332: 1015-24. PMID 14499605 DOI: 10.1016/S0022-2836(03)00970-7  1
2003 Lee K, Zhan X, Gao J, Qiu J, Feng Y, Meganathan R, Cohen SN, Georgiou G. RraA. a protein inhibitor of RNase E activity that globally modulates RNA abundance in E. coli. Cell. 114: 623-34. PMID 13678585 DOI: 10.1016/j.cell.2003.08.003  1
2003 Lafond R, Zhan X, Georgiou G. Screening and selection strategies for disulfide isomerase activity. Methods in Molecular Biology (Clifton, N.J.). 230: 239-57. PMID 12824588 DOI: 10.1385/1-59259-396-8:239  1
2003 Georgiou G, Masip L. Biochemistry. An overoxidation journey with a return ticket. Science (New York, N.Y.). 300: 592-4. PMID 12714731 DOI: 10.1126/science.1084976  1
2002 Maynard JA, Maassen CB, Leppla SH, Brasky K, Patterson JL, Iverson BL, Georgiou G. Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity. Nature Biotechnology. 20: 597-601. PMID 12042864 DOI: 10.1038/nbt0602-597  1
2002 Maynard JA, Chen G, Georgiou G, Iverson BL. In vitro scanning-saturation mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 182: 149-63. PMID 11768962  1
2001 Levy R, Weiss R, Chen G, Iverson BL, Georgiou G. Production of correctly folded Fab antibody fragment in the cytoplasm of Escherichia coli trxB gor mutants via the coexpression of molecular chaperones. Protein Expression and Purification. 23: 338-47. PMID 11676610 DOI: 10.1006/prep.2001.1520  1
2001 Bessette PH, Qiu J, Bardwell JC, Swartz JR, Georgiou G. Effect of sequences of the active-site dipeptides of DsbA and DsbC on in vivo folding of multidisulfide proteins in Escherichia coli. Journal of Bacteriology. 183: 980-8. PMID 11208797 DOI: 10.1128/JB.183.3.980-988.2001  1
1999 Zhan X, Schwaller M, Gilbert HF, Georgiou G. Facilitating the formation of disulfide bonds in the Escherichia coli periplasm via coexpression of yeast protein disulfide isomerase. Biotechnology Progress. 15: 1033-8. PMID 10585186 DOI: 10.1021/bp990083r  1
1999 Bessette PH, Aslund F, Beckwith J, Georgiou G. Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm. Proceedings of the National Academy of Sciences of the United States of America. 96: 13703-8. PMID 10570136 DOI: 10.1073/pnas.96.24.13703  1
1999 Bessette PH, Cotto JJ, Gilbert HF, Georgiou G. In vivo and in vitro function of the Escherichia coli periplasmic cysteine oxidoreductase DsbG. The Journal of Biological Chemistry. 274: 7784-92. PMID 10075670 DOI: 10.1074/jbc.274.12.7784  0.6
1998 Qiu J, Swartz JR, Georgiou G. Expression of active human tissue-type plasminogen activator in Escherichia coli. Applied and Environmental Microbiology. 64: 4891-6. PMID 9835579  1
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