Joseph M. Castellano - Publications

Affiliations: 
2017- Neuroscience Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Aging, Neurodegeneration, Alzheimer's disease
Website:
http://labs.neuroscience.mssm.edu/project/castellano-lab/

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hemmer BM, Philippi SM, Castellano JM. Youth-associated platelet-derived chemokine reverses brain aging through neuroimmune mechanisms. Trends in Molecular Medicine. PMID 37945435 DOI: 10.1016/j.molmed.2023.10.007  0.787
2023 Ferreira AC, Hemmer BM, Philippi SM, Grau-Perales AB, Rosenstadt JL, Liu H, Zhu JD, Kareva T, Ahfeldt T, Varghese M, Hof PR, Castellano JM. Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity. Molecular Psychiatry. PMID 37914840 DOI: 10.1038/s41380-023-02296-5  0.708
2022 Luo J, Nguyen A, Villeda S, Zhang H, Ding Z, Lindsey D, Bieri G, Castellano JM, Beaupre GS, Wyss-Coray T. Corrigendum: Long-Term Cognitive Impairments and Pathological Alterations in a Mouse Model of Repetitive Mild Traumatic Brain Injury. Frontiers in Neurology. 13: 730576. PMID 35847232 DOI: 10.3389/fneur.2022.730576  0.713
2022 Machlovi SI, Neuner SM, Hemmer BM, Khan R, Liu Y, Huang M, Zhu JD, Castellano JM, Cai D, Marcora E, Goate AM. APOE4 genotype confers transcriptomic and functional alterations to primary mouse microglia. Neurobiology of Disease. 105615. PMID 35031484 DOI: 10.1016/j.nbd.2022.105615  0.629
2020 Brigger D, Riether C, van Brummelen R, Mosher KI, Shiu A, Ding Z, Zbären N, Gasser P, Guntern P, Yousef H, Castellano JM, Storni F, Graff-Radford N, Britschgi M, Grandgirard D, et al. Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nature Metabolism. PMID 32694825 DOI: 10.1038/s42255-020-0228-3  0.751
2019 Ferreira AC, Castellano JM. Leaving the Lights on Using Gamma Entrainment to Protect against Neurodegeneration. Neuron. 102: 901-902. PMID 31170394 DOI: 10.1016/J.Neuron.2019.05.020  0.748
2018 Castellano JM. Blood-Based Therapies to Combat Aging. Gerontology. 1-6. PMID 30196300 DOI: 10.1159/000492573  0.325
2017 Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature. PMID 28424512 DOI: 10.1038/Nature22067  0.621
2017 Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, et al. Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity. The Journal of Experimental Medicine. PMID 28298456 DOI: 10.1084/Jem.20162011  0.765
2016 Castellano JM, Palner M, Li SB, Freeman GM, Nguyen A, Shen B, Stan T, Mosher KI, Chin FT, de Lecea L, Luo J, Wyss-Coray T. In vivo assessment of behavioral recovery and circulatory exchange in the peritoneal parabiosis model. Scientific Reports. 6: 29015. PMID 27364522 DOI: 10.1038/Srep29015  0.578
2016 Zhang XD, Wang H, Antaris AL, Li L, Diao S, Ma R, Nguyen A, Hong G, Ma Z, Wang J, Zhu S, Castellano JM, Wyss-Coray T, Liang Y, Luo J, et al. Traumatic Brain Injury Imaging in the Second Near-Infrared Window with a Molecular Fluorophore. Advanced Materials (Deerfield Beach, Fla.). PMID 27253071 DOI: 10.1002/Adma.201600706  0.551
2015 Castellano JM, Kirby ED, Wyss-Coray T. Blood-Borne Revitalization of the Aged Brain. Jama Neurology. PMID 26237737 DOI: 10.1001/Jamaneurol.2015.1616  0.734
2015 Shieh P, Dien VT, Beahm BJ, Castellano JM, Wyss-Coray T, Bertozzi CR. CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum. Journal of the American Chemical Society. 137: 7145-51. PMID 25902190 DOI: 10.1021/Jacs.5B02383  0.505
2014 Baruch K, Deczkowska A, David E, Castellano JM, Miller O, Kertser A, Berkutzki T, Barnett-Itzhaki Z, Bezalel D, Wyss-Coray T, Amit I, Schwartz M. Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function. Science (New York, N.Y.). 346: 89-93. PMID 25147279 DOI: 10.1126/Science.1252945  0.636
2014 Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, ... Castellano JM, et al. Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. Jama Neurology. 71: 1228-36. PMID 25111166 DOI: 10.1001/Jamaneurol.2014.2011  0.516
2014 Villeda SA, Plambeck KE, Middeldorp J, Castellano JM, Mosher KI, Luo J, Smith LK, Bieri G, Lin K, Berdnik D, Wabl R, Udeochu J, Wheatley EG, Zou B, Simmons DA, et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nature Medicine. 20: 659-63. PMID 24793238 DOI: 10.1038/Nm.3569  0.736
2014 Luo J, Nguyen A, Villeda S, Zhang H, Ding Z, Lindsey D, Bieri G, Castellano JM, Beaupre GS, Wyss-Coray T. Long-term cognitive impairments and pathological alterations in a mouse model of repetitive mild traumatic brain injury. Frontiers in Neurology. 5: 12. PMID 24550885 DOI: 10.3389/Fneur.2014.00012  0.739
2014 Deczkowska A, Baruch K, David E, Castellano JM, Miller O, Kertser A, Berkutzki T, Barnett-Itzhaki Z, Bezalel D, Wyss-coray T, Amit I, Schwartz M. Aging-induced immunological signature of the brain's choroid plexus negatively regulates neurogenesis and cognitive function Journal of Neuroimmunology. 275: 124. DOI: 10.1016/J.Jneuroim.2014.08.331  0.567
2013 Verghese PB, Castellano JM, Garai K, Wang Y, Jiang H, Shah A, Bu G, Frieden C, Holtzman DM. ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions. Proceedings of the National Academy of Sciences of the United States of America. 110: E1807-16. PMID 23620513 DOI: 10.1073/Pnas.1220484110  0.763
2013 Ulrich JD, Burchett JM, Restivo JL, Schuler DR, Verghese PB, Mahan TE, Landreth GE, Castellano JM, Jiang H, Cirrito JR, Holtzman DM. In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis. Molecular Neurodegeneration. 8: 13. PMID 23601557 DOI: 10.1186/1750-1326-8-13  0.768
2012 Castellano JM, Deane R, Gottesdiener AJ, Verghese PB, Stewart FR, West T, Paoletti AC, Kasper TR, DeMattos RB, Zlokovic BV, Holtzman DM. Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 15502-7. PMID 22927427 DOI: 10.1073/Pnas.1206446109  0.801
2011 Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM. Human apoE isoforms differentially regulate brain amyloid-β peptide clearance. Science Translational Medicine. 3: 89ra57. PMID 21715678 DOI: 10.1126/Scitranslmed.3002156  0.757
2011 Verghese PB, Castellano JM, Holtzman DM. Apolipoprotein E in Alzheimer's disease and other neurological disorders. The Lancet. Neurology. 10: 241-52. PMID 21349439 DOI: 10.1016/S1474-4422(10)70325-2  0.758
2011 Castellano J, Verghese P, Stewart F, DeMattos R, Holtzman D. P2-221: Synthetic human apoE particles differentially regulate brain interstitial amyloid-beta levels Alzheimer's & Dementia. 7: S383-S383. DOI: 10.1016/J.Jalz.2011.05.1103  0.744
2010 Castellano JM, Stewart FR, May PC, DeMattos RB, Paul SM, Holtzman DM. O4-02-03: Soluble Aβ clearance from the brain interstitial fluid of PDAPP mice is human apoE isoform-dependent Alzheimer's & Dementia. 6: S153-S153. DOI: 10.1016/J.Jalz.2010.05.475  0.572
2009 Kim J, Castellano JM, Jiang H, Basak JM, Parsadanian M, Pham V, Mason SM, Paul SM, Holtzman DM. Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance. Neuron. 64: 632-44. PMID 20005821 DOI: 10.1016/J.Neuron.2009.11.013  0.78
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