Year |
Citation |
Score |
2020 |
Manoranjan B, Venugopal C, Bakhshinyan D, Adile AA, Richards L, Kameda-Smith MM, Whitley O, Dvorkin-Gheva A, Subapanditha M, Savage N, Tatari N, McKenna D, Bassey-Archibong B, Winegarden N, Hallett R, ... ... Doble BW, et al. Wnt activation as a therapeutic strategy in medulloblastoma. Nature Communications. 11: 4323. PMID 32859895 DOI: 10.1038/S41467-020-17953-4 |
0.301 |
|
2020 |
Zhang M, Lai Y, Krupalnik V, Guo P, Guo X, Zhou J, Xu Y, Yu Z, Liu L, Jiang A, Li W, Abdul MM, Ma G, Li N, Fu X, ... ... Doble BW, et al. β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus. Science Advances. 6: eaba1593. PMID 32832621 DOI: 10.1126/Sciadv.Aba1593 |
0.363 |
|
2017 |
Moreira S, Polena E, Gordon V, Abdulla S, Mahendram S, Cao J, Blais A, Wood GA, Dvorkin-Gheva A, Doble BW. A Single TCF Transcription Factor, Regardless of Its Activation Capacity, Is Sufficient for Effective Trilineage Differentiation of ESCs. Cell Reports. 20: 2424-2438. PMID 28877475 DOI: 10.1016/J.Celrep.2017.08.043 |
0.358 |
|
2017 |
Manoranjan B, Venugopal C, Pavlovic Z, Bakhshinyan D, Kameda-Smith M, Subapanditha M, Mahendram S, Moffat J, Doble BW, Singh S. Abstract 5831: Activated Wnt signaling for the treatment of recurrent medulloblastoma Cancer Research. 77: 5831-5831. DOI: 10.1158/1538-7445.Am2017-5831 |
0.328 |
|
2015 |
Khan KA, Dô F, Marineau A, Doyon P, Clément JF, Woodgett JR, Doble BW, Servant MJ. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Molecular and Cellular Biology. 35: 3029-43. PMID 26100021 DOI: 10.1128/Mcb.00344-15 |
0.331 |
|
2015 |
Meredith GD, D'Ippolito A, Dudas M, Zeidner LC, Hostetter L, Faulds K, Arnold TH, Popkie AP, Doble BW, Marnellos G, Adams C, Wang Y, Phiel CJ. Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells. Molecular Biology of the Cell. 26: 2139-50. PMID 25833708 DOI: 10.1091/Mbc.E15-01-0013 |
0.326 |
|
2015 |
Manoranjan B, Venugopal C, Mahendram S, Moreira S, Hallett R, Vijayakumar T, Bakhshinyan D, McFarlane N, Hassell J, Doble B, Singh S. MB-15 * ACTIVATED Wnt SIGNALING TARGETS Sox2+ TREATMENT-REFRACTORY Shh-DEPENDENT MEDULLOBLASTOMA STEM CELLS Neuro-Oncology. 17: iii23-iii23. DOI: 10.1093/Neuonc/Nov061.91 |
0.31 |
|
2014 |
Bartman CM, Egelston J, Kattula S, Zeidner LC, D'Ippolito A, Doble BW, Phiel CJ. Gene Expression Profiling in Mouse Embryonic Stem Cells Reveals Glycogen Synthase Kinase-3-Dependent Targets of Phosphatidylinositol 3-Kinase and Wnt/β-Catenin Signaling Pathways. Frontiers in Endocrinology. 5: 133. PMID 25165462 DOI: 10.3389/Fendo.2014.00133 |
0.344 |
|
2013 |
Holowacz T, Alexson TO, Coles BL, Doble BW, Kelly KF, Woodgett JR, Van Der Kooy D. The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin. Biology Open. 2: 812-21. PMID 23951407 DOI: 10.1242/Bio.20131941 |
0.413 |
|
2013 |
Mahendram S, Kelly KF, Paez-Parent S, Mahmood S, Polena E, Cooney AJ, Doble BW. Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation. Plos One. 8: e65320. PMID 23724138 DOI: 10.1371/Journal.Pone.0065320 |
0.328 |
|
2012 |
Manoranjan B, Venugopal C, McFarlane N, Doble BW, Dunn SE, Scheinemann K, Singh SK. Medulloblastoma stem cells: where development and cancer cross pathways. Pediatric Research. 71: 516-22. PMID 22430388 DOI: 10.1038/Pr.2011.62 |
0.304 |
|
2011 |
Kelly KF, Ng DY, Jayakumaran G, Wood GA, Koide H, Doble BW. β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism. Cell Stem Cell. 8: 214-27. PMID 21295277 DOI: 10.1016/J.Stem.2010.12.010 |
0.34 |
|
2010 |
Popkie AP, Zeidner LC, Albrecht AM, D'Ippolito A, Eckardt S, Newsom DE, Groden J, Doble BW, Aronow B, McLaughlin KJ, White P, Phiel CJ. Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci. The Journal of Biological Chemistry. 285: 41337-47. PMID 21047779 DOI: 10.1074/Jbc.M110.170704 |
0.395 |
|
2010 |
Zhou J, Lal H, Chen X, Shang X, Song J, Li Y, Kerkela R, Doble BW, MacAulay K, DeCaul M, Koch WJ, Farber J, Woodgett J, Gao E, Force T. GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice Journal of Clinical Investigation. 120: 2280-2291. PMID 20516643 DOI: 10.1172/Jci41407 |
0.373 |
|
2009 |
Kim WY, Wang X, Wu Y, Doble BW, Patel S, Woodgett JR, Snider WD. GSK-3 is a master regulator of neural progenitor homeostasis. Nature Neuroscience. 12: 1390-7. PMID 19801986 DOI: 10.1038/Nn.2408 |
0.363 |
|
2008 |
Kerkela R, Kockeritz L, Macaulay K, Zhou J, Doble BW, Beahm C, Greytak S, Woulfe K, Trivedi CM, Woodgett JR, Epstein JA, Force T, Huggins GS. Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation. The Journal of Clinical Investigation. 118: 3609-18. PMID 18830417 DOI: 10.1172/Jci36245 |
0.378 |
|
2008 |
Patel S, Doble BW, MacAulay K, Sinclair EM, Drucker DJ, Woodgett JR. Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action. Molecular and Cellular Biology. 28: 6314-28. PMID 18694957 DOI: 10.1128/Mcb.00763-08 |
0.3 |
|
2008 |
Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P, Smith A. The ground state of embryonic stem cell self-renewal. Nature. 453: 519-23. PMID 18497825 DOI: 10.1038/Nature06968 |
0.37 |
|
2008 |
Thornton TM, Pedraza-Alva G, Deng B, Wood CD, Aronshtam A, Clements JL, Sabio G, Davis RJ, Matthews DE, Doble B, Rincon M. Phosphorylation by p38 MAPK as an alternative pathway for GSK3β inactivation Science. 320: 667-670. PMID 18451303 DOI: 10.1126/Science.1156037 |
0.393 |
|
2007 |
Doble BW, Woodgett JR. Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions. Cells, Tissues, Organs. 185: 73-84. PMID 17587811 DOI: 10.1159/000101306 |
0.399 |
|
2007 |
Doble BW, Patel S, Wood GA, Kockeritz LK, Woodgett JR. Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Developmental Cell. 12: 957-71. PMID 17543867 DOI: 10.1016/J.Devcel.2007.04.001 |
0.324 |
|
2006 |
Kockeritz L, Doble B, Patel S, Woodgett JR. Glycogen synthase kinase-3--an overview of an over-achieving protein kinase. Current Drug Targets. 7: 1377-88. PMID 17100578 DOI: 10.2174/1389450110607011377 |
0.436 |
|
2004 |
Sheikh F, Hirst CJ, Jin Y, Bock ME, Fandrich RR, Nickel BE, Doble BW, Kardami E, Cattini PA. Inhibition of TGFbeta signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis. Cardiovascular Research. 64: 516-25. PMID 15537505 DOI: 10.1016/J.Cardiores.2004.08.009 |
0.608 |
|
2004 |
Patel S, Doble B, Woodgett JR. Glycogen synthase kinase-3 in insulin and Wnt signalling: A double-edged sword? Biochemical Society Transactions. 32: 803-808. PMID 15494020 DOI: 10.1042/Bst0320803 |
0.381 |
|
2004 |
Doble BW, Dang X, Ping P, Fandrich RR, Nickel BE, Jin Y, Cattini PA, Kardami E. Phosphorylation of serine 262 in the gap junction protein connexin-43 regulates DNA synthesis in cell-cell contact forming cardiomyocytes. Journal of Cell Science. 117: 507-14. PMID 14702389 DOI: 10.1242/Jcs.00889 |
0.632 |
|
2003 |
Kardami E, Banerji S, Doble BW, Dang X, Fandrich RR, Jin Y, Cattini PA. PKC-dependent phosphorylation may regulate the ability of connexin43 to inhibit DNA synthesis. Cell Communication & Adhesion. 10: 293-7. PMID 14681031 DOI: 10.1080/Cac.10.4-6.293.297 |
0.639 |
|
2003 |
Dang X, Doble BW, Kardami E. The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth. Molecular and Cellular Biochemistry. 242: 35-8. PMID 12619863 DOI: 10.1007/978-1-4757-4712-6_5 |
0.6 |
|
2003 |
Doble BW, Woodgett JR. GSK-3: tricks of the trade for a multi-tasking kinase. Journal of Cell Science. 116: 1175-86. PMID 12615961 DOI: 10.1242/Jcs.00384 |
0.415 |
|
2002 |
Jiang ZS, Padua RR, Ju H, Doble BW, Jin Y, Hao J, Cattini PA, Dixon IM, Kardami E. Acute protection of ischemic heart by FGF-2: involvement of FGF-2 receptors and protein kinase C. American Journal of Physiology. Heart and Circulatory Physiology. 282: H1071-80. PMID 11834506 DOI: 10.1152/Ajpheart.00290.2001 |
0.63 |
|
2001 |
Doble BW, Ping P, Fandrich RR, Cattini PA, Kardami E. Protein kinase C-epsilon mediates phorbol ester-induced phosphorylation of connexin-43. Cell Communication & Adhesion. 8: 253-6. PMID 12064598 DOI: 10.3109/15419060109080733 |
0.622 |
|
2001 |
Sun G, Doble BW, Sun JM, Fandrich RR, Florkiewicz R, Kirshenbaum L, Davie JR, Cattini PA, Kardami E. CUG-initiated FGF-2 induces chromatin compaction in cultured cardiac myocytes and in vitro. Journal of Cellular Physiology. 186: 457-67. PMID 11169985 DOI: 10.1002/1097-4652(2000)9999:999<000::Aid-Jcp1044>3.0.Co;2-2 |
0.624 |
|
2000 |
Doble BW, Ping P, Kardami E. The epsilon subtype of protein kinase C is required for cardiomyocyte connexin-43 phosphorylation. Circulation Research. 86: 293-301. PMID 10679481 DOI: 10.1161/01.Res.86.3.293 |
0.67 |
|
1998 |
Kardami E, Doble BW. Cardiomyocyte gap junctions: a target of growth-promoting signaling. Trends in Cardiovascular Medicine. 8: 180-7. PMID 21235931 DOI: 10.1016/S1050-1738(98)00007-3 |
0.679 |
|
1998 |
Padua RR, Merle PL, Doble BW, Yu CH, Zahradka P, Pierce GN, Panagia V, Kardami E. FGF-2-induced negative inotropism and cardioprotection are inhibited by chelerythrine: involvement of sarcolemmal calcium-independent protein kinase C. Journal of Molecular and Cellular Cardiology. 30: 2695-709. PMID 9990540 DOI: 10.1006/Jmcc.1998.0832 |
0.647 |
|
1997 |
Nagy JI, Li WE, Roy C, Doble BW, Gilchrist JS, Kardami E, Hertzberg EL. Selective monoclonal antibody recognition and cellular localization of an unphosphorylated form of connexin43. Experimental Cell Research. 236: 127-36. PMID 9344592 DOI: 10.1006/Excr.1997.3716 |
0.616 |
|
1996 |
Doble BW, Chen Y, Bosc DG, Litchfield DW, Kardami E. Fibroblast growth factor-2 decreases metabolic coupling and stimulates phosphorylation as well as masking of connexin43 epitopes in cardiac myocytes. Circulation Research. 79: 647-58. PMID 8831488 DOI: 10.1161/01.Res.79.4.647 |
0.676 |
|
1995 |
Doble BW, Kardami E. Basic fibroblast growth factor stimulates connexin-43 expression and intercellular communication of cardiac fibroblasts. Molecular and Cellular Biochemistry. 143: 81-7. PMID 7776963 DOI: 10.1007/Bf00925930 |
0.643 |
|
1995 |
Kardami E, Liu L, Pasumarthi SK, Doble BW, Cattini PA. Regulation of basic fibroblast growth factor (bFGF) and FGF receptors in the heart. Annals of the New York Academy of Sciences. 752: 353-69. PMID 7755280 DOI: 10.1111/J.1749-6632.1995.Tb17444.X |
0.618 |
|
1994 |
Pasumarthi KB, Doble BW, Kardami E, Cattini PA. Over-expression of CUG- or AUG-initiated forms of basic fibroblast growth factor in cardiac myocytes results in similar effects on mitosis and protein synthesis but distinct nuclear morphologies. Journal of Molecular and Cellular Cardiology. 26: 1045-60. PMID 7799445 DOI: 10.1006/Jmcc.1994.1125 |
0.633 |
|
1993 |
Liu L, Doble BW, Kardami E. Perinatal phenotype and hypothyroidism are associated with elevated levels of 21.5- to 22-kDa basic fibroblast growth factor in cardiac ventricles. Developmental Biology. 157: 507-16. PMID 8500657 DOI: 10.1006/Dbio.1993.1153 |
0.626 |
|
1993 |
Kardami E, Padua RR, Pasumarthi KBS, Liu L, Doble BW, Davey SE, Cattini PA. Basic fibroblast growth factor in cardiac myocytes: expression and effects Developments in Cardiovascular Medicine. 147: 55-75. DOI: 10.1007/978-1-4615-3098-5_5 |
0.636 |
|
1991 |
Kardami E, Stoski RM, Doble BW, Yamamoto T, Hertzberg EL, Nagy JI. Biochemical and ultrastructural evidence for the association of basic fibroblast growth factor with cardiac gap junctions. The Journal of Biological Chemistry. 266: 19551-7. PMID 1918064 |
0.601 |
|
1991 |
Kardami E, Liu L, Doble BW. Basic fibroblast growth factor in cultured cardiac myocytes. Annals of the New York Academy of Sciences. 638: 244-55. PMID 1785804 DOI: 10.1111/J.1749-6632.1991.Tb49035.X |
0.639 |
|
1990 |
Doble BW, Fandrich RR, Liu L, Padua RR, Kardami E. Calcium protects pituitary basic fibroblast growth factors from limited proteolysis by co-purifying proteases. Biochemical and Biophysical Research Communications. 173: 1116-22. PMID 2268315 DOI: 10.1016/S0006-291X(05)80901-5 |
0.58 |
|
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