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Robert D. Guzy, Ph.D. - Publications

Affiliations: 
2005 University of Chicago, Chicago, IL 
Area:
Cell Biology
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 El-Baz LMF, Shoukry NM, Hafez HS, Guzy RD, Salem ML. Fibroblast Growth Factor 2 Augments Transforming Growth Factor Beta 1 Induced Epithelial-mesenchymal Transition in Lung Cell Culture Model. Iranian Journal of Allergy, Asthma, and Immunology. 19: 348-361. PMID 33463102 DOI: 10.18502/Ijaai.V19I4.4110  0.333
2020 Lee TH, Yeh CF, Lee YT, Shih YC, Chen YT, Hung CT, You MY, Wu PC, Shentu TP, Huang RT, Lin YS, Wu YF, Lin SJ, Lu FL, Tsao PN, ... ... Guzy RD, et al. Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization. Nature Communications. 11: 4254. PMID 32848143 DOI: 10.1038/S41467-020-18047-X  0.349
2019 Dorry SJ, Ansbro BO, Ornitz DM, Mutlu GM, Guzy RD. FGFR2 is Required for AEC2 Homeostasis and Survival Following Bleomycin-Induced Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 31860803 DOI: 10.1165/Rcmb.2019-0079Oc  0.326
2018 Reyfman PA, Walter JM, Joshi N, Anekalla KR, McQuattie-Pimentel AC, Chiu S, Fernandez R, Akbarpour M, Chen CI, Ren Z, Verma R, Abdala-Valencia H, Nam K, Chi M, Han S, ... ... Guzy RD, et al. Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 30554520 DOI: 10.1164/Rccm.201712-2410Oc  0.304
2018 Koo HY, El-Baz LMF, House SL, Cilvik SN, Dorry SJ, Shoukry NM, Salem ML, Hafez HS, Dulin NO, Ornitz DM, Guzy RD. Fibroblast growth factor 2 decreases bleomycin-induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation. The Journal of Pathology. PMID 29873400 DOI: 10.1002/Path.5106  0.342
2017 Hamanaka RB, Nigdelioglu R, Meliton AY, Tian Y, Witt LJ, O'Leary E, Sun KA, Woods PS, Wu D, Ansbro B, Ard S, Rohde JM, Dulin NO, Guzy RD, Mutlu GM. Inhibition of PHGDH Attenuates Bleomycin-induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 29019702 DOI: 10.1165/Rcmb.2017-0186Oc  0.31
2017 Guzy RD, Li L, Smith C, Dorry SJ, Koo HY, Chen L, Ornitz DM. Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling. The Journal of Biological Chemistry. PMID 28487375 DOI: 10.1074/Jbc.M117.791764  0.346
2015 Guzy RD, Stoilov I, Elton TJ, Mecham RP, Ornitz DM. Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin. American Journal of Respiratory Cell and Molecular Biology. 52: 116-28. PMID 24988442 DOI: 10.1165/Rcmb.2014-0184Oc  0.309
2013 Waypa GB, Marks JD, Guzy RD, Mungai PT, Schriewer JM, Dokic D, Ball MK, Schumacker PT. Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation. American Journal of Respiratory and Critical Care Medicine. 187: 424-32. PMID 23328522 DOI: 10.1164/Rccm.201207-1294Oc  0.729
2011 Loor G, Kondapalli J, Iwase H, Chandel NS, Waypa GB, Guzy RD, Vanden Hoek TL, Schumacker PT. Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. Biochimica Et Biophysica Acta. 1813: 1382-94. PMID 21185334 DOI: 10.1016/J.Bbamcr.2010.12.008  0.66
2010 Waypa GB, Marks JD, Guzy R, Mungai PT, Schriewer J, Dokic D, Schumacker PT. Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells. Circulation Research. 106: 526-35. PMID 20019331 DOI: 10.1161/Circresaha.109.206334  0.732
2008 Guzy RD, Sharma B, Bell E, Chandel NS, Schumacker PT. Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis. Molecular and Cellular Biology. 28: 718-31. PMID 17967865 DOI: 10.1128/Mcb.01338-07  0.595
2007 Iwase H, Robin E, Guzy RD, Mungai PT, Vanden Hoek TL, Chandel NS, Levraut J, Schumacker PT. Nitric oxide during ischemia attenuates oxidant stress and cell death during ischemia and reperfusion in cardiomyocytes. Free Radical Biology & Medicine. 43: 590-9. PMID 17640569 DOI: 10.1016/J.Freeradbiomed.2007.05.017  0.705
2007 Guzy RD, Mack MM, Schumacker PT. Mitochondrial complex III is required for hypoxia-induced ROS production and gene transcription in yeast. Antioxidants & Redox Signaling. 9: 1317-28. PMID 17627464 DOI: 10.1089/Ars.2007.1708  0.625
2007 Robin E, Guzy RD, Loor G, Iwase H, Waypa GB, Marks JD, Hoek TL, Schumacker PT. Oxidant stress during simulated ischemia primes cardiomyocytes for cell death during reperfusion. The Journal of Biological Chemistry. 282: 19133-43. PMID 17488710 DOI: 10.1074/Jbc.M701917200  0.641
2007 Loor G, Kondapalli J, Sharma B, Guzy R, Schumacker P. Mechanisms of cell death in oxidant stress and ischemia-reperfusion injury The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A448-C  0.579
2006 Waypa GB, Guzy R, Mungai PT, Mack MM, Marks JD, Roe MW, Schumacker PT. Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells. Circulation Research. 99: 970-8. PMID 17008601 DOI: 10.1161/01.Res.0000247068.75808.3F  0.733
2006 Guzy RD, Schumacker PT. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Experimental Physiology. 91: 807-19. PMID 16857720 DOI: 10.1113/Expphysiol.2006.033506  0.671
2005 Guzy RD, Hoyos B, Robin E, Chen H, Liu L, Mansfield KD, Simon MC, Hammerling U, Schumacker PT. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metabolism. 1: 401-8. PMID 16054089 DOI: 10.1016/J.Cmet.2005.05.001  0.635
2005 Mansfield KD, Guzy RD, Pan Y, Young RM, Cash TP, Schumacker PT, Simon MC. Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation. Cell Metabolism. 1: 393-9. PMID 16054088 DOI: 10.1016/J.Cmet.2005.05.003  0.603
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