Zhijun Luo - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Cell Biology, Molecular Biology

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chen Q, Jin J, Guo W, Tang Z, Luo Y, Ying Y, Lin H, Luo Z. PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2. International Journal of Molecular Sciences. 23. PMID 35955931 DOI: 10.3390/ijms23158798  0.392
2022 Zhao J, Luo Z. Discovery of Raf Family Is a Milestone in Deciphering the Ras-Mediated Intracellular Signaling Pathway. International Journal of Molecular Sciences. 23. PMID 35563547 DOI: 10.3390/ijms23095158  0.41
2020 Lin H, Shi F, Jiang S, Wang Y, Zou J, Ying Y, Huang D, Luo L, Yan X, Luo Z. Metformin attenuates trauma-induced heterotopic ossification via inhibition of Bone Morphogenetic Protein signalling. Journal of Cellular and Molecular Medicine. PMID 33169942 DOI: 10.1111/jcmm.16076  0.374
2020 Yi Y, Chen D, Ao J, Zhang W, Yi J, Ren X, Fei J, Li F, Niu M, Chen H, Luo Y, Luo Z, Xiao ZJ. Transcriptional suppression of AMPKα1 promotes breast cancer metastasis upon oncogene activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32193335 DOI: 10.1073/Pnas.1914786117  0.449
2019 Jiang S, Shi F, Lin H, Ying Y, Luo L, Huang D, Luo Z. Inonotus Obliquus Polysaccharides Induces Apoptosis of Lung Cancer Cells and Alters Energy Metabolism via the LKB1/AMPK Axis. International Journal of Biological Macromolecules. PMID 31751687 DOI: 10.1016/J.Ijbiomac.2019.10.174  0.364
2019 Li Y, Sun R, Zou J, Ying Y, Luo Z. Dual Roles of the AMP-Activated Protein Kinase Pathway in Angiogenesis. Cells. 8. PMID 31331111 DOI: 10.3390/Cells8070752  0.409
2019 Jiang S, Wang Y, Luo L, Shi F, Zou J, Lin H, Ying Y, Luo Y, Zhan Z, Liu P, Zhu B, Huang D, Luo Z. AMP-activated protein kinase regulates cancer cell growth and metabolism via nuclear and mitochondria events. Journal of Cellular and Molecular Medicine. PMID 30993829 DOI: 10.1111/Jcmm.14279  0.435
2018 Li N, Feng Y, Hu Y, He C, Xie C, Ouyang Y, Artim SC, Huang D, Zhu Y, Luo Z, Ge Z, Lu N. Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway. Journal of Experimental & Clinical Cancer Research : Cr. 37: 280. PMID 30466467 DOI: 10.1186/S13046-018-0962-5  0.303
2018 Gao J, Ye J, Ying Y, Lin H, Luo Z. Negative regulation of TGF-β by AMPK and implications in the treatment of associated disorders. Acta Biochimica Et Biophysica Sinica. 50: 523-531. PMID 29873702 DOI: 10.1093/Abbs/Gmy028  0.346
2017 Lin H, Ying Y, Wang YY, Wang G, Jiang SS, Huang D, Luo L, Chen YG, Gerstenfeld LC, Luo Z. AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of in vitro osteogenic differentiation. Biochimica Et Biophysica Acta. PMID 28847510 DOI: 10.1016/J.Bbamcr.2017.08.009  0.493
2017 Ying Y, Ueta T, Jiang S, Lin H, Wang Y, Vavvas D, Wen R, Chen YG, Luo Z. Metformin inhibits ALK1-mediated angiogenesis via activation of AMPK. Oncotarget. PMID 28427181 DOI: 10.18632/Oncotarget.15825  0.426
2017 Liang Z, Li W, Liu J, Li J, He F, Jiang Y, Yang L, Li P, Wang B, Wang Y, Ren Y, Yang J, Luo Z, Vaziri C, Liu P. Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells. Scientific Reports. 7: 41776. PMID 28150753 DOI: 10.1038/Srep41776  0.331
2016 Wang Y, Li Y, Hu G, Huang X, Rao H, Xiong X, Luo Z, Lu Q, Luo S. Nek2A phosphorylates and stabilizes SuFu: A new strategy of Gli2/Hedgehog signaling regulatory. Cellular Signalling. PMID 27297360 DOI: 10.1016/J.Cellsig.2016.06.010  0.347
2016 He H, Liu D, Lin H, Jiang S, Ying Y, Chun S, Deng H, Zaia J, Wen R, Luo Z. Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein and has multiple functions. Biochimica Et Biophysica Acta. PMID 27033522 DOI: 10.1016/J.Bbamcr.2016.03.022  0.382
2015 Li NS, Zou JR, Lin H, Ke R, He XL, Xiao L, Huang D, Luo L, Lv N, Luo Z. LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 26718214 DOI: 10.1007/S13277-015-4639-9  0.36
2015 Huang D, He X, Zou J, Guo P, Jiang S, Lv N, Alekseyev Y, Luo L, Luo Z. Negative regulation of Bmi-1 by AMPK and implication in cancer progression. Oncotarget. PMID 26717043 DOI: 10.18632/Oncotarget.6748  0.321
2015 Lin H, Li N, He H, Ying Y, Sunkara S, Luo L, Lv N, Huang D, Luo Z. AMPK Inhibits the Stimulatory Effects of TGF-β on Smad2/3 Activity, Cell Migration and Epithelial to Mesenchymal Transition. Molecular Pharmacology. PMID 26424816 DOI: 10.1124/Mol.115.099549  0.43
2015 Yang Z, Xie C, Xu W, Liu G, Cao X, Li W, Chen J, Zhu Y, Luo S, Luo Z, Lu N. Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway. Oncotarget. PMID 26376616 DOI: 10.18632/Oncotarget.5577  0.418
2015 Luo L, Jiang S, Huang D, Lu N, Luo Z. MLK3 phophorylates AMPK independently of LKB1. Plos One. 10: e0123927. PMID 25874865 DOI: 10.1371/Journal.Pone.0123927  0.495
2014 He G, Zhang YW, Lee JH, Zeng SX, Wang YV, Luo Z, Dong XC, Viollet B, Wahl GM, Lu H. AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity. Molecular and Cellular Biology. 34: 148-57. PMID 24190973 DOI: 10.1128/Mcb.00670-13  0.512
2013 Luo L, Huang W, Tao R, Hu N, Xiao ZX, Luo Z. ATM and LKB1 dependent activation of AMPK sensitizes cancer cells to etoposide-induced apoptosis. Cancer Letters. 328: 114-9. PMID 22960274 DOI: 10.1016/J.Canlet.2012.08.034  0.387
2012 Wang B, Zhang H, Zhu M, Luo Z, Peng Y. MEK1-ERKs signal cascade is required for the replication of Enterovirus 71 (EV71). Antiviral Research. 93: 110-7. PMID 22101247 DOI: 10.1016/J.Antiviral.2011.11.001  0.374
2011 Chakrabarti P, English T, Karki S, Qiang L, Tao R, Kim J, Luo Z, Farmer SR, Kandror KV. SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL. Journal of Lipid Research. 52: 1693-701. PMID 21743036 DOI: 10.1194/Jlr.M014647  0.411
2011 Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, Jiang B, Park O, Luo Z, Lefai E, Shyy JY, Gao B, Wierzbicki M, Verbeuren TJ, Shaw RJ, Cohen RA, et al. AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice. Cell Metabolism. 13: 376-88. PMID 21459323 DOI: 10.1016/J.Cmet.2011.03.009  0.416
2011 Li Y, Xu S, Giles A, Nakamura K, Lee JW, Hou X, Donmez G, Li J, Luo Z, Walsh K, Guarente L, Zang M. Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1664-79. PMID 21321189 DOI: 10.1096/Fj.10-173492  0.316
2011 Zhou J, Yang Z, Tsuji T, Gong J, Xie J, Chen C, Li W, Amar S, Luo Z. LITAF and TNFSF15, two downstream targets of AMPK, exert inhibitory effects on tumor growth. Oncogene. 30: 1892-900. PMID 21217782 DOI: 10.1038/Onc.2010.575  0.387
2010 Luo Z, Zang M, Guo W. AMPK as a metabolic tumor suppressor: control of metabolism and cell growth. Future Oncology (London, England). 6: 457-70. PMID 20222801 DOI: 10.2217/Fon.09.174  0.353
2010 Zhang H, Feng H, Luo L, Zhou Q, Luo Z, Peng Y. Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2. Virus Research. 150: 22-7. PMID 20172001 DOI: 10.1016/J.Virusres.2010.02.007  0.438
2010 Tao R, Gong J, Luo X, Zang M, Guo W, Wen R, Luo Z. AMPK exerts dual regulatory effects on the PI3K pathway. Journal of Molecular Signaling. 5: 1. PMID 20167101 DOI: 10.1186/1750-2187-5-1  0.472
2009 Ma T, Zhao Y, Kwak YD, Yang Z, Thompson R, Luo Z, Xu H, Liao FF. Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11226-36. PMID 19741129 DOI: 10.1523/Jneurosci.6150-08.2009  0.375
2009 Zhou J, Huang W, Tao R, Ibaragi S, Lan F, Ido Y, Wu X, Alekseyev YO, Lenburg ME, Hu GF, Luo Z. Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells. Oncogene. 28: 1993-2002. PMID 19347029 DOI: 10.1038/onc.2009.63  0.336
2009 Chen Y, Zhou K, Wang R, Liu Y, Kwak YD, Ma T, Thompson RC, Zhao Y, Smith L, Gasparini L, Luo Z, Xu H, Liao FF. Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription. Proceedings of the National Academy of Sciences of the United States of America. 106: 3907-12. PMID 19237574 DOI: 10.1073/Pnas.0807991106  0.347
2008 Zang M, Gong J, Luo L, Zhou J, Xiang X, Huang W, Huang Q, Luo X, Olbrot M, Peng Y, Chen C, Luo Z. Characterization of Ser338 phosphorylation for Raf-1 activation. The Journal of Biological Chemistry. 283: 31429-37. PMID 18775988 DOI: 10.1074/Jbc.M802855200  0.541
2008 Chakrabarti P, Anno T, Manning BD, Luo Z, Kandror KV. The mammalian target of rapamycin complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5'-untranslated region in the expression of leptin messenger ribonucleic acid. Molecular Endocrinology (Baltimore, Md.). 22: 2260-7. PMID 18653778 DOI: 10.1210/Me.2008-0148  0.355
2006 Ruderman NB, Keller C, Richard AM, Saha AK, Luo Z, Xiang X, Giralt M, Ritov VB, Menshikova EV, Kelley DE, Hidalgo J, Pedersen BK, Kelly M. Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome. Diabetes. 55: S48-54. PMID 17130644 DOI: 10.2337/Db06-S007  0.342
2006 Park S, Rath O, Beach S, Xiang X, Kelly SM, Luo Z, Kolch W, Yeung KC. Regulation of RKIP binding to the N-region of the Raf-1 kinase. Febs Letters. 580: 6405-12. PMID 17097642 DOI: 10.1016/J.Febslet.2006.10.054  0.436
2006 Saha AK, Persons K, Safer JD, Luo Z, Holick MF, Ruderman NB. AMPK regulation of the growth of cultured human keratinocytes. Biochemical and Biophysical Research Communications. 349: 519-24. PMID 16949049 DOI: 10.1016/J.Bbrc.2006.08.107  0.402
2006 Chadee DN, Xu D, Hung G, Andalibi A, Lim DJ, Luo Z, Gutmann DH, Kyriakis JM. Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein. Proceedings of the National Academy of Sciences of the United States of America. 103: 4463-8. PMID 16537381 DOI: 10.1073/Pnas.0510651103  0.526
2006 Jin Y, Dai MS, Lu SZ, Xu Y, Luo Z, Zhao Y, Lu H. 14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation. The Embo Journal. 25: 1207-18. PMID 16511572 DOI: 10.1038/Sj.Emboj.7601010  0.373
2005 Zhu J, Balan V, Bronisz A, Balan K, Sun H, Leicht DT, Luo Z, Qin J, Avruch J, Tzivion G. Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK binding. Molecular Biology of the Cell. 16: 4733-44. PMID 16093354 DOI: 10.1091/Mbc.E05-02-0090  0.546
2005 Luo Z, Saha AK, Xiang X, Ruderman NB. AMPK, the metabolic syndrome and cancer. Trends in Pharmacological Sciences. 26: 69-76. PMID 15681023 DOI: 10.1016/J.Tips.2004.12.011  0.427
2004 Xiang X, Saha AK, Wen R, Ruderman NB, Luo Z. AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms. Biochemical and Biophysical Research Communications. 321: 161-7. PMID 15358229 DOI: 10.1016/J.Bbrc.2004.06.133  0.395
2004 Hayne C, Xiang X, Luo Z. MEK inhibition and phosphorylation of serine 4 on B23 are two coincident events in mitosis. Biochemical and Biophysical Research Communications. 321: 675-80. PMID 15358159 DOI: 10.1016/J.Bbrc.2004.07.024  0.704
2003 Cai D, Iyer A, Felekkis KN, Near RI, Luo Z, Chernoff J, Albanese C, Pestell RG, Lerner A. AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter. Cancer Research. 63: 6802-8. PMID 14583477  0.362
2003 Song Y, Zhao L, Tao W, Laties AM, Luo Z, Wen R. Photoreceptor protection by cardiotrophin-1 in transgenic rats with the rhodopsin mutation s334ter. Investigative Ophthalmology & Visual Science. 44: 4069-75. PMID 12939330 DOI: 10.1167/Iovs.02-1130  0.31
2003 Huang YZ, Zang M, Xiong WC, Luo Z, Mei L. Erbin suppresses the MAP kinase pathway. The Journal of Biological Chemistry. 278: 1108-14. PMID 12379659 DOI: 10.1074/Jbc.M205413200  0.496
2002 Xiang X, Zang M, Waelde CA, Wen R, Luo Z. Phosphorylation of 338SSYY341 regulates specific interaction between Raf-1 and MEK1. The Journal of Biological Chemistry. 277: 44996-5003. PMID 12244094 DOI: 10.1074/Jbc.M203953200  0.499
2002 Xu CW, Luo Z. Inactivation of Ras function by allele-specific peptide aptamers. Oncogene. 21: 5753-7. PMID 12173045 DOI: 10.1038/Sj.Onc.1205680  0.338
2002 Luo ZG, Wang Q, Zhou JZ, Wang J, Luo Z, Liu M, He X, Wynshaw-Boris A, Xiong WC, Lu B, Mei L. Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1. Neuron. 35: 489-505. PMID 12165471 DOI: 10.1016/S0896-6273(02)00783-3  0.314
2002 Tomás E, Lin YS, Dagher Z, Saha A, Luo Z, Ido Y, Ruderman NB. Hyperglycemia and insulin resistance: possible mechanisms. Annals of the New York Academy of Sciences. 967: 43-51. PMID 12079834 DOI: 10.1111/J.1749-6632.2002.Tb04262.X  0.36
2002 Xiang X, Yuan M, Song Y, Ruderman N, Wen R, Luo Z. 14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1. Molecular Endocrinology (Baltimore, Md.). 16: 552-62. PMID 11875115 DOI: 10.1210/Mend.16.3.0790  0.335
2002 Zang M, Hayne C, Luo Z. Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1. The Journal of Biological Chemistry. 277: 4395-405. PMID 11733498 DOI: 10.1074/Jbc.M110000200  0.724
2001 Lin Y, Itani SI, Kurowski TG, Dean DJ, Luo Z, Yaney GC, Ruderman NB. Inhibition of insulin signaling and glycogen synthesis by phorbol dibutyrate in rat skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 281: E8-E15. PMID 11404218 DOI: 10.1152/Ajpendo.2001.281.1.E8  0.368
2001 Lenz G, Gonçalves D, Luo Z, Avruch J, Rodnight R, Neary JT. Extracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte cultures. Journal of Neurochemistry. 77: 1001-9. PMID 11359865 DOI: 10.1046/J.1471-4159.2001.00299.X  0.508
2001 Zang M, Waelde CA, Xiang X, Rana A, Wen R, Luo Z. Microtubule integrity regulates Pak leading to Ras-independent activation of Raf-1. insights into mechanisms of Raf-1 activation. The Journal of Biological Chemistry. 276: 25157-65. PMID 11274179 DOI: 10.1074/Jbc.M100152200  0.551
2000 Tzivion G, Luo Z, Avruch J. Calyculin A-induced vimentin phosphorylation sequesters 14-3-3 and displaces other 14-3-3 partners in vivo. Journal of Biological Chemistry. 275: 29772-29778. PMID 10887173 DOI: 10.1074/Jbc.M001207200  0.449
2000 Hayne C, Tzivion G, Luo Z. Raf-1/MEK/MAPK pathway is necessary for the G2/M transition induced by nocodazole. Journal of Biological Chemistry. 275: 31876-31882. PMID 10884385 DOI: 10.1074/Jbc.M002766200  0.714
2000 Lenz G, Gottfried C, Luo Z, Avruch J, Rodnight R, Nie WJ, Kang Y, Neary JT. P(2Y) purinoceptor subtypes recruit different mek activators in astrocytes. British Journal of Pharmacology. 129: 927-36. PMID 10696092 DOI: 10.1038/Sj.Bjp.0703138  0.354
1999 Kurowski TG, Lin Y, Luo Z, Tsichlis PN, Buse MG, Heydrick SJ, Ruderman NB. Hyperglycemia inhibits insulin activation of Akt/protein kinase B but not phosphatidylinositol 3-kinase in rat skeletal muscle. Diabetes. 48: 658-63. PMID 10078574 DOI: 10.2337/Diabetes.48.3.658  0.326
1998 Tzivion G, Luo Z, Avruch J. A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity Nature. 394: 88-92. PMID 9665134 DOI: 10.1038/27938  0.557
1997 Marti A, Luo Z, Cunningham C, Ohta Y, Hartwig J, Stossel TP, Kyriakis JM, Avruch J. Actin-biding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-α activation of SAPK in melanoma cells Journal of Biological Chemistry. 272: 2620-2628. PMID 9006895 DOI: 10.1074/Jbc.272.5.2620  0.463
1997 Luo Z, Diaz B, Marshall MS, Avruch J. An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ. Molecular and Cellular Biology. 17: 46-53. PMID 8972184 DOI: 10.1128/Mcb.17.1.46  0.416
1996 Luo Z, Tzivion G, Belshaw PJ, Vavvas D, Marshall M, Avruch J. Oligomerization activates c-Raf-1 through a Ras-dependent mechanism. Nature. 383: 181-5. PMID 8774885 DOI: 10.1038/383181A0  0.505
1996 Si J, Luo Z, Mei L. Induction of acetylcholine receptor gene expression by ARIA requires activation of mitogen-activated protein kinase. The Journal of Biological Chemistry. 271: 19752-9. PMID 8702681 DOI: 10.1074/Jbc.271.33.19752  0.487
1995 Luo Z, Zhang X, Rapp U, Avruch J. Identification of the 14.3.3 ζ Domains Important for Self-association and Raf Binding Journal of Biological Chemistry. 270: 23681-23687. PMID 7559537 DOI: 10.1074/Jbc.270.40.23681  0.505
1994 Singh IS, Luo Z, Kozlowski MT, Erlichman J. Association of USF and c-Myc with a helix-loop-helix-consensus motif in the core promoter of the murine type II beta regulatory subunit gene of cyclic adenosine 3', 5'-monophosphate-dependent protein kinase. Molecular Endocrinology (Baltimore, Md.). 8: 1163-74. PMID 7838149 DOI: 10.1210/Mend.8.9.7838149  0.369
1993 Keryer G, Luo Z, Cavadore JC, Erlichman J, Bornens M. Phosphorylation of the regulatory subunit of type II beta cAMP-dependent protein kinase by cyclin B/p34cdc2 kinase impairs its binding to microtubule-associated protein 2. Proceedings of the National Academy of Sciences of the United States of America. 90: 5418-22. PMID 8516283 DOI: 10.1073/Pnas.90.12.5418  0.442
1991 Singh IS, Luo ZJ, Eng A, Erlichman J. Molecular cloning and characterization of the promoter region of the mouse regulatory subunit RII beta of type II cAMP-dependent protein kinase. Biochemical and Biophysical Research Communications. 178: 221-6. PMID 2069562 DOI: 10.1016/0006-291X(91)91802-J  0.379
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