Year |
Citation |
Score |
2012 |
Garbarino J, Pan M, Chin HF, Lund FW, Maxfield FR, Breslow JL. STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC. Journal of Lipid Research. 53: 2716-25. PMID 23033213 DOI: 10.1194/Jlr.M032227 |
0.45 |
|
2012 |
Maxwell KN, Breslow JL. Antibodies to PCSK9: a superior way to lower LDL cholesterol? Circulation Research. 111: 274-7. PMID 22821907 DOI: 10.1161/CIRCRESAHA.112.275859 |
0.345 |
|
2012 |
Brown WV, Breslow J, Ballantyne C. Clinical use of genetic typing in human lipid disorders. Journal of Clinical Lipidology. 6: 199-207. PMID 22658144 DOI: 10.1016/J.Jacl.2012.02.007 |
0.307 |
|
2010 |
Burkhardt R, Toh SA, Lagor WR, Birkeland A, Levin M, Li X, Robblee M, Fedorov VD, Yamamoto M, Satoh T, Akira S, Kathiresan S, Breslow JL, Rader DJ. Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice. The Journal of Clinical Investigation. 120: 4410-4. PMID 21084752 DOI: 10.1172/Jci44213 |
0.426 |
|
2010 |
Riegelhaupt JJ, Waase MP, Garbarino J, Cruz DE, Breslow JL. Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism. Journal of Lipid Research. 51: 1134-43. PMID 19965609 DOI: 10.1194/Jlr.M003095 |
0.576 |
|
2009 |
Zhou C, King N, Chen KY, Breslow JL. Activation of PXR induces hypercholesterolemia in wild-type and accelerates atherosclerosis in apoE deficient mice. Journal of Lipid Research. 50: 2004-13. PMID 19436068 DOI: 10.1194/Jlr.M800608-Jlr200 |
0.411 |
|
2005 |
Maxwell KN, Breslow JL. Proprotein convertase subtilisin kexin 9: the third locus implicated in autosomal dominant hypercholesterolemia. Current Opinion in Lipidology. 16: 167-72. PMID 15767856 |
0.338 |
|
2005 |
Soccio RE, Adams RM, Maxwell KN, Breslow JL. Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress. The Journal of Biological Chemistry. 280: 19410-8. PMID 15760897 DOI: 10.1074/Jbc.M501778200 |
0.706 |
|
2005 |
Maxwell KN, Fisher EA, Breslow JL. Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment. Proceedings of the National Academy of Sciences of the United States of America. 102: 2069-74. PMID 15677715 DOI: 10.1073/pnas.0409736102 |
0.467 |
|
2004 |
Soccio RE, Breslow JL. Intracellular cholesterol transport. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1150-60. PMID 15130918 DOI: 10.1161/01.Atv.0000131264.66417.D5 |
0.696 |
|
2004 |
Maxwell KN, Breslow JL. Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype. Proceedings of the National Academy of Sciences of the United States of America. 101: 7100-5. PMID 15118091 DOI: 10.1073/pnas.0402133101 |
0.523 |
|
2004 |
Tiemann M, Han Z, Soccio R, Bollineni J, Shefer S, Sehayek E, Breslow JL. Cholesterol feeding of mice expressing cholesterol 7alpha-hydroxylase increases bile acid pool size despite decreased enzyme activity. Proceedings of the National Academy of Sciences of the United States of America. 101: 1846-51. PMID 14762172 DOI: 10.1073/Pnas.0308426100 |
0.697 |
|
2003 |
Maxwell KN, Soccio RE, Duncan EM, Sehayek E, Breslow JL. Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice. Journal of Lipid Research. 44: 2109-19. PMID 12897189 DOI: 10.1194/Jlr.M300203-Jlr200 |
0.697 |
|
2003 |
Sehayek E, Duncan EM, Yu HJ, Petukhova L, Breslow JL. Loci controlling plasma non-HDL and HDL cholesterol levels in a C57BL /6J x CASA /Rk intercross. Journal of Lipid Research. 44: 1744-50. PMID 12810823 DOI: 10.1194/jlr.M300139-JLR200 |
0.369 |
|
2003 |
Sehayek E, Wang R, Ono JG, Zinchuk VS, Duncan EM, Shefer S, Vance DE, Ananthanarayanan M, Chait BT, Breslow JL. Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol. Journal of Lipid Research. 44: 1605-13. PMID 12810817 DOI: 10.1194/Jlr.M200488-Jlr200 |
0.335 |
|
2003 |
Soccio RE, Breslow JL. StAR-related lipid transfer (START) proteins: mediators of intracellular lipid metabolism. The Journal of Biological Chemistry. 278: 22183-6. PMID 12724317 DOI: 10.1074/Jbc.R300003200 |
0.713 |
|
2003 |
Chen F, Ma L, Dawson PA, Sinal CJ, Sehayek E, Gonzalez FJ, Breslow J, Ananthanarayanan M, Shneider BL. Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter. The Journal of Biological Chemistry. 278: 19909-16. PMID 12456679 DOI: 10.1074/Jbc.M207903200 |
0.38 |
|
2002 |
Han Z, Heath SC, Shmulewitz D, Li W, Auerbach SB, Blundell ML, Lehner T, Ott J, Stoffel M, Friedman JM, Breslow JL. Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. American Journal of Medical Genetics. 110: 234-42. PMID 12116231 DOI: 10.1002/Ajmg.10445 |
0.324 |
|
2002 |
Romanowski MJ, Soccio RE, Breslow JL, Burley SK. Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain Proceedings of the National Academy of Sciences of the United States of America. 99: 6949-6954. PMID 12011453 DOI: 10.1073/Pnas.052140699 |
0.701 |
|
2002 |
Soccio RE, Adams RM, Romanowski MJ, Sehayek E, Burley SK, Breslow JL. The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6. Proceedings of the National Academy of Sciences of the United States of America. 99: 6943-8. PMID 12011452 DOI: 10.1073/Pnas.052143799 |
0.73 |
|
2002 |
Merkel M, Heeren J, Dudeck W, Rinninger F, Radner H, Breslow JL, Goldberg IJ, Zechner R, Greten H. Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in the presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake. The Journal of Biological Chemistry. 277: 7405-11. PMID 11751882 DOI: 10.1074/jbc.M107914200 |
0.379 |
|
2001 |
Shih DQ, Bussen M, Sehayek E, Ananthanarayanan M, Shneider BL, Suchy FJ, Shefer S, Bollileni JS, Gonzalez FJ, Breslow JL, Stoffel M. Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism. Nature Genetics. 27: 375-82. PMID 11279518 DOI: 10.1038/86871 |
0.462 |
|
2000 |
Merkel M, Carasco W, Hudgins L, Breslow J. Dietary monounsaturated fatty acids and carbohydrates increase VLDL-cholesterol and atherosclerosis in mice via an apo E dependent pathway Atherosclerosis. 151: 113. DOI: 10.1016/S0021-9150(00)80510-9 |
0.393 |
|
1999 |
Weng W, Li L, Van Bennekum AM, Potter SH, Harrison EH, Blanen WS, Breslow JL, Fisher EA. Intestinal absorption of dietary cholesteryl ester is decreased but retinyl ester absorption is normal in carboxyl ester lipase knockout mice Biochemistry. 38: 4143-4149. PMID 10194330 DOI: 10.1021/bi981679a |
0.356 |
|
1997 |
Hayek T, Attias J, Coleman R, Breslow J, Keidar S. 4.P.10 The effect of the angiotensin converting enzyme (ACE) inhibitor fosinopril and the angiotensin receptor antagonist losartan on the susceptibility of plasma low density lipoprotein to lipid peroxidation and on the progression of atherosclerosis in the apo E deficient transgenic mice Atherosclerosis. 134: 298. DOI: 10.1016/S0021-9150(97)89538-X |
0.399 |
|
1996 |
Yang TP, Agellon LB, Walsh A, Breslow JL, Tall AR. Alternative splicing of the human cholesteryl ester transfer protein gene in transgenic mice. Exon exclusion modulates gene expression in response to dietary or developmental change. The Journal of Biological Chemistry. 271: 12603-9. PMID 8647871 DOI: 10.1074/jbc.271.21.12603 |
0.326 |
|
1994 |
Breslow J. Lipoproteins and heart disease. Transgenic mice models are helping in the search for new therapies. Bio/Technology (Nature Publishing Company). 12: 365-7, 369-70. PMID 7764681 DOI: 10.1038/Nbt0494-365 |
0.312 |
|
1992 |
Plump AS, Smith JD, Hayek T, Aalto-Setälä K, Walsh A, Verstuyft JG, Rubin EM, Breslow JL. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell. 71: 343-53. PMID 1423598 DOI: 10.1016/0092-8674(92)90362-G |
0.347 |
|
1983 |
Karathanasis SK, Norum RA, Zannis VI, Breslow JL. An inherited polymorphism in the human apolipoprotein A-I gene locus related to the development of atherosclerosis Nature. 301: 718-720. PMID 6402711 DOI: 10.1038/301718a0 |
0.382 |
|
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