Year |
Citation |
Score |
2023 |
Zhu K, Kazim N, Yue J, Yen A. Correction: Vacuolin‑1 enhances RA‑induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP‑76 axis subject to endosomal regulation that drives late differentiation steps. Cell & Bioscience. 13: 22. PMID 36737806 DOI: 10.1186/s13578-023-00965-0 |
0.311 |
|
2022 |
Zhu K, Kazim N, Yue J, Yen A. Vacuolin-1 enhances RA-induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP-76 axis subject to endosomal regulation that drives late differentiation steps. Cell & Bioscience. 12: 179. PMID 36329484 DOI: 10.1186/s13578-022-00911-6 |
0.486 |
|
2021 |
Kazim N, Yen A. Evidence of off-target effects of bosutinib that promote retinoic acid-induced differentiation of non-APL AML cells. Cell Cycle (Georgetown, Tex.). 1-14. PMID 34836491 DOI: 10.1080/15384101.2021.2005275 |
0.537 |
|
2021 |
Kazim N, Yen A. Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells. Oncotarget. 12: 1147-1164. PMID 34136084 DOI: 10.18632/oncotarget.27969 |
0.531 |
|
2020 |
Zhu K, Yue J, Yen A. Depleting interferon regulatory factor-1(IRF-1) with CRISPR/Cas9 attenuates inducible oxidative metabolism without affecting RA-induced differentiation in HL-60 human AML cells. Faseb Bioadvances. 2: 354-364. PMID 32617521 DOI: 10.1096/fba.2020-00004 |
0.501 |
|
2020 |
Rashid A, Wang R, Zhang L, Yue J, Yang M, Yen A. Dissecting the novel partners of nuclear c-Raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation. Experimental Cell Research. 111989. PMID 32283065 DOI: 10.1016/J.Yexcr.2020.111989 |
0.434 |
|
2020 |
Rashid A, Duan X, Gao F, Yang M, Yen A. Roscovitine enhances all- retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation. Oncotarget. 11: 1017-1036. PMID 32256976 DOI: 10.18632/Oncotarget.27508 |
0.537 |
|
2020 |
Rashid A, Duan X, Gao F, Yang M, Yen A. Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor. Cellular Signalling. 109555. PMID 32032659 DOI: 10.1016/j.cellsig.2020.109555 |
0.488 |
|
2018 |
Bunaciu RP, MacDonald RJ, Jensen HA, Gao F, Wang X, Johnson L, Varner JD, Yen A. Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML. Leukemia & Lymphoma. 1-12. PMID 30570341 DOI: 10.1080/10428194.2018.1543880 |
0.396 |
|
2018 |
MacDonald RJ, Yen A. CXCR5 overexpression in HL-60 cells enhances chemotaxis toward CXCL13 without anticipated interaction partners or enhanced MAPK signaling. In Vitro Cellular & Developmental Biology. Animal. PMID 30276608 DOI: 10.1007/s11626-018-0293-z |
0.434 |
|
2018 |
MacDonald RJ, Bunaciu RP, Ip V, Dai D, Tran D, Varner JD, Yen A. Src family kinase inhibitor bosutinib enhances retinoic acid-induced differentiation of HL-60 leukemia cells. Leukemia & Lymphoma. 1-11. PMID 29569971 DOI: 10.1080/10428194.2018.1452213 |
0.445 |
|
2018 |
Supnick HT, Bunaciu RP, Yen A. The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1,25-dihydroxyvitamin D3-induced differentiation of HL-60 myeloblastic leukemia cells. Oncotarget. 9: 9808-9824. PMID 29515772 DOI: 10.18632/Oncotarget.24275 |
0.338 |
|
2018 |
Bunaciu RP, MacDonald RJ, Gao F, Johnson LM, Varner JD, Wang X, Nataraj S, Guzman ML, Yen A. Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment. Oncotarget. 9: 4134-4149. PMID 29423110 DOI: 10.18632/Oncotarget.23642 |
0.341 |
|
2017 |
MacDonald RJ, Shrimp JH, Jiang H, Zhang L, Lin H, Yen A. Probing the requirement for CD38 in retinoic acid-induced HL-60 cell differentiation with a small molecule dimerizer and genetic knockout. Scientific Reports. 7: 17406. PMID 29234114 DOI: 10.1038/S41598-017-17720-4 |
0.459 |
|
2017 |
Tasseff R, Jensen HA, Congleton J, Dai D, Rogers KV, Sagar A, Bunaciu RP, Yen A, Varner JD. An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program. Scientific Reports. 7: 14327. PMID 29085021 DOI: 10.1038/S41598-017-14523-5 |
0.783 |
|
2016 |
Wallace AS, Supnick HT, Bunaciu RP, Yen A. RRD-251 enhances All-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells. Oncotarget. PMID 27331409 DOI: 10.18632/Oncotarget.10136 |
0.542 |
|
2015 |
Jensen HA, Yourish HB, Bunaciu RP, Varner JD, Yen A. Induced myelomonocytic differentiation in leukemia cells is accompanied by noncanonical transcription factor expression. Febs Open Bio. 5: 789-800. PMID 26566473 DOI: 10.1016/J.Fob.2015.09.008 |
0.516 |
|
2015 |
Bunaciu RP, Jensen HA, MacDonald RJ, LaTocha DH, Varner JD, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. Plos One. 10: e0135668. PMID 26287494 DOI: 10.1371/Journal.Pone.0135668 |
0.543 |
|
2015 |
Ibabao CN, Bunaciu RP, Schaefer DM, Yen A. The AhR agonist VAF347 augments retinoic acid-induced differentiation in leukemia cells. Febs Open Bio. 5: 308-18. PMID 25941627 DOI: 10.1016/J.Fob.2015.04.002 |
0.618 |
|
2015 |
Jensen HA, Bunaciu RP, Varner JD, Yen A. GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation. Cellular Signalling. 27: 1666-75. PMID 25817574 DOI: 10.1016/J.Cellsig.2015.03.014 |
0.561 |
|
2015 |
Kim BJ, Zhao S, Bunaciu RP, Yen A, Wu M. A 3D in situ cell counter reveals that breast tumor cell (MDA-MB-231) proliferation rate is reduced by the collagen matrix density. Biotechnology Progress. PMID 25683564 DOI: 10.1002/Btpr.2062 |
0.35 |
|
2015 |
Wallace AS, Geil WM, Yen A. Abstract 2031: RRD-251 enhances retinoic acid induced differentiation of myeloblastic leukemic cells Cancer Research. 75: 2031-2031. DOI: 10.1158/1538-7445.Am2015-2031 |
0.497 |
|
2014 |
Jensen HA, Bunaciu RP, Ibabao CN, Myers R, Varner JD, Yen A. Retinoic acid therapy resistance progresses from unilineage to bilineage in HL-60 leukemic blasts. Plos One. 9: e98929. PMID 24922062 DOI: 10.1371/Journal.Pone.0098929 |
0.519 |
|
2014 |
Congleton J, Shen M, MacDonald R, Malavasi F, Yen A. Phosphorylation of c-Cbl and p85 PI3K driven by all-trans retinoic acid and CD38 depends on Lyn kinase activity. Cellular Signalling. 26: 1589-97. PMID 24686085 DOI: 10.1016/J.Cellsig.2014.03.021 |
0.794 |
|
2014 |
Shrimp JH, Hu J, Dong M, Wang BS, MacDonald R, Jiang H, Hao Q, Yen A, Lin H. Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe. Journal of the American Chemical Society. 136: 5656-63. PMID 24660829 DOI: 10.1021/Ja411046J |
0.436 |
|
2014 |
Geil WM, Yen A. Nuclear Raf-1 kinase regulates the CXCR5 promoter by associating with NFATc3 to drive retinoic acid-induced leukemic cell differentiation. The Febs Journal. 281: 1170-80. PMID 24330068 DOI: 10.1111/Febs.12693 |
0.568 |
|
2013 |
Bunaciu RP, Yen A. 6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells. Molecular Cancer. 12: 39. PMID 23656719 DOI: 10.1186/1476-4598-12-39 |
0.501 |
|
2013 |
Jensen HA, Styskal LE, Tasseff R, Bunaciu RP, Congleton J, Varner JD, Yen A. The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells. Plos One. 8: e58621. PMID 23554907 DOI: 10.1371/Journal.Pone.0058621 |
0.815 |
|
2012 |
Congleton J, MacDonald R, Yen A. Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK-dependent differentiation of myeloid leukemia cells. Leukemia. 26: 1180-8. PMID 22182854 DOI: 10.1038/Leu.2011.390 |
0.785 |
|
2011 |
Shen M, Bunaciu RP, Congleton J, Jensen HA, Sayam LG, Varner JD, Yen A. Interferon regulatory factor-1 binds c-Cbl, enhances mitogen activated protein kinase signaling and promotes retinoic acid-induced differentiation of HL-60 human myelo-monoblastic leukemia cells. Leukemia & Lymphoma. 52: 2372-9. PMID 21740303 DOI: 10.3109/10428194.2011.603449 |
0.818 |
|
2011 |
Tasseff R, Nayak S, Song SO, Yen A, Varner JD. Modeling and analysis of retinoic acid induced differentiation of uncommitted precursor cells. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 578-91. PMID 21437295 DOI: 10.1039/C0Ib00141D |
0.527 |
|
2011 |
Bunaciu RP, Yen A. Activation of the aryl hydrocarbon receptor AhR Promotes retinoic acid-induced differentiation of myeloblastic leukemia cells by restricting expression of the stem cell transcription factor Oct4. Cancer Research. 71: 2371-80. PMID 21262915 DOI: 10.1158/0008-5472.Can-10-2299 |
0.547 |
|
2011 |
Congleton J, Jiang H, Malavasi F, Lin H, Yen A. ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary. Experimental Cell Research. 317: 910-9. PMID 21156171 DOI: 10.1016/J.Yexcr.2010.12.003 |
0.795 |
|
2010 |
Reiterer G, Chen L, Tassef R, Varner JD, Chen CY, Yen A. RAF associates with phosphorylated nuclear BubR1 during endoreduplication induced by JAK inhibition. Cell Cycle (Georgetown, Tex.). 9: 3297-304. PMID 20703093 DOI: 10.4161/Cc.9.16.12631 |
0.402 |
|
2010 |
Nayak S, Shen M, Bunaciu RP, Bloom SE, Varner JD, Yen A. Arsenic trioxide cooperates with all trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RARalpha negative human myeloblastic leukemia cells. Leukemia & Lymphoma. 51: 1734-47. PMID 20615082 DOI: 10.3109/10428194.2010.501535 |
0.562 |
|
2009 |
Shen M, Yen A. c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrest. The Journal of Biological Chemistry. 284: 25664-77. PMID 19635790 DOI: 10.1074/Jbc.M109.014241 |
0.503 |
|
2009 |
Smith J, Bunaciu RP, Reiterer G, Coder D, George T, Asaly M, Yen A. Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells. Experimental Cell Research. 315: 2241-8. PMID 19298812 DOI: 10.1016/J.Yexcr.2009.03.004 |
0.541 |
|
2009 |
Tallini YN, Greene KS, Craven M, Spealman A, Breitbach M, Smith J, Fisher PJ, Steffey M, Hesse M, Doran RM, Woods A, Singh B, Yen A, Fleischmann BK, Kotlikoff MI. c-kit expression identifies cardiovascular precursors in the neonatal heart. Proceedings of the National Academy of Sciences of the United States of America. 106: 1808-13. PMID 19193854 DOI: 10.1073/Pnas.0808920106 |
0.382 |
|
2009 |
Jiang H, Congleton J, Liu Q, Merchant P, Malavasi F, Lee HC, Hao Q, Yen A, Lin H. Mechanism-based small molecule probes for labeling CD38 on live cells. Journal of the American Chemical Society. 131: 1658-9. PMID 19191692 DOI: 10.1021/Ja808387G |
0.767 |
|
2009 |
Shen M, Yen A. Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells. Oncology. 76: 91-100. PMID 19127080 DOI: 10.1159/000188664 |
0.567 |
|
2008 |
Shen M, Yen A. c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells. Cancer Research. 68: 8761-9. PMID 18974118 DOI: 10.1158/0008-5472.Can-08-1058 |
0.608 |
|
2008 |
Kauss MA, Reiterer G, Bunaciu RP, Yen A. Human myeloblastic leukemia cells (HL-60) express a membrane receptor for estrogen that signals and modulates retinoic acid-induced cell differentiation. Experimental Cell Research. 314: 2999-3006. PMID 18692045 DOI: 10.1016/J.Yexcr.2008.07.015 |
0.536 |
|
2008 |
Reiterer G, Bunaciu RP, Smith JL, Yen A. Inhibiting the platelet derived growth factor receptor increases signs of retinoic acid syndrome in myeloid differentiated HL-60 cells. Febs Letters. 582: 2508-14. PMID 18571505 DOI: 10.1016/J.Febslet.2008.06.016 |
0.499 |
|
2008 |
Wang J, Yen A. A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. The Journal of Biological Chemistry. 283: 4375-86. PMID 18006504 DOI: 10.1074/Jbc.M708471200 |
0.564 |
|
2007 |
Reiterer G, Yen A. Platelet-derived growth factor receptor regulates myeloid and monocytic differentiation of HL-60 cells. Cancer Research. 67: 7765-72. PMID 17699781 DOI: 10.1158/0008-5472.Can-07-0014 |
0.543 |
|
2007 |
Yen A. Retinoic acid therapy served by ligands cross linking and masking CD38. Leukemia Research. 31: 423-5. PMID 16914201 DOI: 10.1016/J.Leukres.2006.07.003 |
0.359 |
|
2006 |
Reiterer G, Yen A. Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication. Cancer Research. 66: 9083-9. PMID 16982750 DOI: 10.1158/0008-5472.Can-06-0972 |
0.465 |
|
2006 |
Chikamori K, Hill JE, Grabowski DR, Zarkhin E, Grozav AG, Vaziri SA, Wang J, Gudkov AV, Rybicki LR, Bukowski RM, Yen A, Tanimoto M, Ganapathi MK, Ganapathi R. Downregulation of topoisomerase IIbeta in myeloid leukemia cell lines leads to activation of apoptosis following all-trans retinoic acid-induced differentiation/growth arrest. Leukemia. 20: 1809-18. PMID 16932348 DOI: 10.1038/Sj.Leu.2404351 |
0.53 |
|
2006 |
Lamkin TJ, Chin V, Yen A. All-trans retinoic acid induces p62DOK1 and p56DOK2 expression which enhances induced differentiation and G0 arrest of HL-60 leukemia cells. American Journal of Hematology. 81: 603-15. PMID 16823827 DOI: 10.1002/Ajh.20667 |
0.807 |
|
2006 |
Yen A, Varvayanis S, Smith JL, Lamkin TJ. Retinoic acid induces expression of SLP-76: expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells. European Journal of Cell Biology. 85: 117-32. PMID 16439309 DOI: 10.1016/J.Ejcb.2005.09.020 |
0.804 |
|
2006 |
Lamkin TJ, Chin V, Varvayanis S, Smith JL, Sramkoski RM, Jacobberger JW, Yen A. Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. Journal of Cellular Biochemistry. 97: 1328-38. PMID 16329108 DOI: 10.1002/Jcb.20745 |
0.81 |
|
2006 |
Ganapathi M, Chikamori K, Hill J, Grabowski D, Zarkhin E, Grozav A, Vaziri S, Bukowski R, Yen A, Ganapathi R. 493 POSTER Down regulation of topoisomerase IIβ in myeloid leukemia cell lines leads to activation of apoptosis following all-trans retinoic acid-induced differentiation/growth arrest European Journal of Cancer Supplements. 4: 150. DOI: 10.1016/S1359-6349(06)70498-0 |
0.476 |
|
2004 |
Yen A, Lin DM, Lamikin TJ, Varvayanis S. Retinoic acid, bromodeoxyuridine, and the Δ205 mutant polyoma virus middle T antigen regulate expression levels of a common ensemble of proteins associated with early stages of inducing HL-60 leukemic cell differentiation. In Vitro Cellular & Developmental Biology. Animal. 40: 216-41. PMID 27520281 DOI: 10.1290/1543-706X(2004)40<216:Rabatm>2.0.Co;2 |
0.574 |
|
2004 |
Yen A, Lin DM, Lamkin TJ, Varvayanis S. retinoic acid, bromodeoxyuridine, and the Delta 205 mutant polyoma virus middle T antigen regulate expression levels of a common ensemble of proteins associated with early stages of inducing HL-60 leukemic cell differentiation. In Vitro Cellular & Developmental Biology. Animal. 40: 216-41. PMID 15638704 DOI: 10.1290/1543-706X(2004)40<216:RABATM>2.0.CO;2 |
0.804 |
|
2004 |
Flaminio MJ, Yen A, Antczak DF. The proliferation inhibitory proteins p27(Kip1) and retinoblastoma are involved in the control of equine lymphocyte proliferation. Veterinary Immunology and Immunopathology. 102: 363-77. PMID 15541790 DOI: 10.1016/J.Vetimm.2004.07.001 |
0.432 |
|
2004 |
Yen A, Fenning R, Chandraratna R, Walker P, Varvayanis S. A retinoic acid receptor beta/gamma-selective prodrug (tazarotene) plus a retinoid X receptor ligand induces extracellular signal-regulated kinase activation, retinoblastoma hypophosphorylation, G0 arrest, and cell differentiation. Molecular Pharmacology. 66: 1727-37. PMID 15383624 DOI: 10.1124/Mol.104.003475 |
0.537 |
|
2004 |
Wang J, Yen A. A novel retinoic acid-responsive element regulates retinoic acid-induced BLR1 expression. Molecular and Cellular Biology. 24: 2423-43. PMID 14993281 |
0.364 |
|
2002 |
Wightman J, Roberson MS, Lamkin TJ, Varvayanis S, Yen A. Retinoic acid-induced growth arrest and differentiation: retinoic acid up-regulates CD32 (Fc gammaRII) expression, the ectopic expression of which retards the cell cycle. Molecular Cancer Therapeutics. 1: 493-506. PMID 12479267 |
0.811 |
|
2002 |
Battle TE, Yen A. Ectopic expression of CXCR5/BLR1 accelerates retinoic acid- and vitamin D(3)-induced monocytic differentiation of U937 cells. Experimental Biology and Medicine (Maywood, N.J.). 227: 753-62. PMID 12324654 DOI: 10.1177/153537020222700906 |
0.533 |
|
2002 |
Hong HY, Varvayanis S, Yen A. Retinoic acid causes MEK-dependent RAF phosphorylation through RARalpha plus RXR activation in HL-60 cells. Differentiation; Research in Biological Diversity. 68: 55-66. PMID 11683493 DOI: 10.1046/J.1432-0436.2001.068001055.X |
0.477 |
|
2001 |
Yen A, Placanica L, Bloom S, Varvayanis S. Polyomavirus small t antigen prevents retinoic acid-induced retinoblastoma protein hypophosphorylation and redirects retinoic acid-induced G0 arrest and differentiation to apoptosis Journal of Virology. 75: 5302-5314. PMID 11333911 DOI: 10.1128/Jvi.75.11.5302-5314.2001 |
0.556 |
|
2001 |
Yen A, Norman AW, Varvayanis S. Nongenomic vitamin D3 analogs activating ERK2 in HL-60 cells show that retinoic acid-induced differentiation and cell cycle arrest require early concurrent MAPK and RAR and RXR activation [2] In Vitro Cellular and Developmental Biology - Animal. 37: 93-99. PMID 11332745 DOI: 10.1290/1071-2690(2001)037<0093:Nvdaae>2.0.Co;2 |
0.487 |
|
2001 |
Battle TE, Roberson MS, Zhang T, Varvayanis S, Yen A. Retinoic acid-induced blr1 expression requires RARalpha, RXR, and MAPK activation and uses ERK2 but not JNK/SAPK to accelerate cell differentiation. European Journal of Cell Biology. 80: 59-67. PMID 11211936 DOI: 10.1078/0171-9335-00141 |
0.567 |
|
2000 |
Yen A, Varvayanis S. Retinoic acid increases amount of phosphorylated RAF; ectopic expression of cFMS reveals that retinoic acid-induced differentiation is more strongly dependent on ERK2 signaling than induced GO arrest is. In Vitro Cellular & Developmental Biology. Animal. 36: 249-55. PMID 10852350 DOI: 10.1290/1071-2690(2000)036<0249:Raiaop>2.0.Co;2 |
0.527 |
|
2000 |
Battle TE, Levine RA, Yen A. Retinoic acid-induced blr1 expression promotes ERK2 activation and cell differentiation in HL-60 cells. Experimental Cell Research. 254: 287-98. PMID 10640427 DOI: 10.1006/Excr.1999.4766 |
0.558 |
|
1999 |
Yen A, Roberson MS, Varvayanis S. Retinoic acid selectively activates the ERK2 but not JNK/SAPK or p38 MAP kinases when inducing myeloid differentiation. In Vitro Cellular & Developmental Biology. Animal. 35: 527-32. PMID 10548434 DOI: 10.1007/S11626-999-0063-Z |
0.394 |
|
1999 |
Yen A, Cherington V, Schaffhausen B, Marks K, Varvayanis S. Transformation-defective polyoma middle T antigen mutants defective in PLCgamma, PI-3, or src kinase activation enhance ERK2 activation and promote retinoic acid-induced, cell differentiation like wild-type middle T. Experimental Cell Research. 248: 538-51. PMID 10222145 DOI: 10.1006/Excr.1999.4423 |
0.482 |
|
1999 |
Townsend KJ, Zhou P, Qian L, Bieszczad CK, Lowrey CH, Yen A, Craig RW. Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation. The Journal of Biological Chemistry. 274: 1801-13. PMID 9880563 DOI: 10.1074/Jbc.274.3.1801 |
0.444 |
|
1998 |
Yen A, Sturgill R. Hypophosphorylation of the RB protein in S and G2 as well as G1 during growth arrest. Experimental Cell Research. 241: 324-31. PMID 9637774 DOI: 10.1006/Excr.1998.4007 |
0.354 |
|
1998 |
Platko JD, Forbes ME, Varvayanis S, Williams MN, Brooks SC, Cherington V, Yen A. Polyoma middle T antigen in HL-60 cells accelerates hematopoietic myeloid and monocytic cell differentiation. Experimental Cell Research. 238: 42-50. PMID 9457055 DOI: 10.1006/Excr.1997.3782 |
0.488 |
|
1997 |
Brooks SC, Sturgill R, Choi J, Yen A. An RXR-selective analog attenuates the RAR alpha-selective analog-induced differentiation and non-G1-restricted growth arrest of NB4 cells. Experimental Cell Research. 234: 259-69. PMID 9260893 DOI: 10.1006/Excr.1997.3620 |
0.413 |
|
1997 |
Platko JD, Yen A. Paxillin increases as retinoic acid or vitamin D3 induce HL-60 cell differentiation. In Vitro Cellular & Developmental Biology. Animal. 33: 84-7. PMID 9081214 DOI: 10.1007/S11626-997-0027-0 |
0.409 |
|
1997 |
Yen A, Sturgill R, Varvayanis S, Chern R. FMS (CSF-1 receptor) prolongs cell cycle and promotes retinoic acid-induced hypophosphorylation of retinoblastoma protein, G1 arrest, and cell differentiation. Experimental Cell Research. 229: 111-25. PMID 8940255 DOI: 10.1006/excr.1996.0349 |
0.478 |
|
1996 |
Yen A, Varvayanis S. The ratio of retinoblastoma (RB) to fos and RB to myc expression during the cell cycle. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 210: 205-12. PMID 8539257 DOI: 10.3181/00379727-210-43940 |
0.436 |
|
1996 |
Brooks Sr, Kazmer S, Levin A, Yen A. Myeloid differentiation and retinoblastoma phosphorylation changes in HL-60 cells induced by retinoic acid receptor- and retinoid X receptor- selective retinoic acid analogs Blood. 87: 227-237. DOI: 10.1182/Blood.V87.1.227.Bloodjournal871227 |
0.402 |
|
1995 |
Yen A, Varvayanis S. RB phosphorylation in sodium butyrate-resistant HL-60 cells: cross-resistance to retinoic acid but not vitamin D3. Journal of Cellular Physiology. 163: 502-9. PMID 7775593 DOI: 10.1002/Jcp.1041630310 |
0.511 |
|
1995 |
Yen A, Varvayanis S. DMSO, sodium butyrate, and TPA induce hypophosphorylation of RB with HL-60 cell differentiation. In Vitro Cellular & Developmental Biology. Animal. 31: 164-7. PMID 7757295 DOI: 10.1007/Bf02639427 |
0.478 |
|
1994 |
Yen A, Varvayanis S. Late dephosphorylation of the RB protein in G2 during the process of induced cell differentiation. Experimental Cell Research. 214: 250-7. PMID 8082728 DOI: 10.1006/excr.1994.1255 |
0.391 |
|
1994 |
Yen A, French T, Russell K, Varvayanis S, Forbes M. Vitamin-regulated retinoblastoma tumor suppressor gene expression in leukemic cells. Advances in Experimental Medicine and Biology. 354: 1-18. PMID 8067277 DOI: 10.1007/978-1-4899-0939-8_1 |
0.373 |
|
1994 |
Yen A, Soong S, Kwon HJ, Yoshida M, Beppu T, Varvayanis S. Enhanced cell differentiation when RB is hypophosphorylated and down-regulated by radicicol, a SRC-kinase inhibitor. Experimental Cell Research. 214: 163-71. PMID 7521842 DOI: 10.1006/excr.1994.1245 |
0.455 |
|
1993 |
Yen A, Coles M, Varvayanis S. 1,25-Dihydroxy vitamin D3 and 12-O-tetradecanoyl phorbol-13-acetate synergistically induce monocytic cell differentiation: FOS and RB expression. Journal of Cellular Physiology. 156: 198-203. PMID 8314857 DOI: 10.1002/Jcp.1041560126 |
0.501 |
|
1993 |
Yen A, Forbes ME, Varvayanis S, Tykocinski ML, Groger RK, Platko JD. C-FMS dependent HL-60 cell differentiation and regulation of RB gene expression. Journal of Cellular Physiology. 157: 379-91. PMID 8227169 DOI: 10.1002/jcp.1041570222 |
0.434 |
|
1992 |
Yen A, Chandler S. Inducers of leukemic cell differentiation cause down-regulation of RB gene expression. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 199: 291-7. PMID 1539032 DOI: 10.3181/00379727-199-43359 |
0.516 |
|
1992 |
Yen A, Samuel V, Forbes M. Regulation of cell proliferation: Late down-regulation of c-myb preceding myelo-monocytic cell differentiation Journal of Cellular Physiology. 153: 147-156. PMID 1522128 DOI: 10.1002/Jcp.1041530119 |
0.503 |
|
1992 |
Yen A, Varvayanis S. RB tumor suppressor gene expression responds to DNA synthesis inhibitors. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 669-72. PMID 1429370 DOI: 10.1007/Bf02631044 |
0.433 |
|
1991 |
Yen A, Chandler S, Sturzenegger-Varvayanis S. Regulated expression of the RB "tumor suppressor gene" in normal lymphocyte mitogenesis: elevated expression in transformed leukocytes and role as a "status quo" gene. Experimental Cell Research. 192: 289-97. PMID 1845796 DOI: 10.1016/0014-4827(91)90188-Z |
0.431 |
|
1991 |
Yen A, Blue J, Forbes M. 1,25-Dihydroxy vitamin D2 induces leukemia cell differentiation. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 518-20. PMID 1653778 DOI: 10.1007/Bf02631279 |
0.373 |
|
1990 |
Mihara K, Cao XR, Yen A, Chandler S, Driscoll B, Murphree AL, T'Ang A, Fung YK. Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product. Science (New York, N.Y.). 246: 1300-3. PMID 2588006 DOI: 10.1126/science.2588006 |
0.319 |
|
1990 |
Cook RT, Keiner JA, Yen A. Ethanol causes accelerated G1 arrest in differentiating HL-60 cells Alcoholism: Clinical and Experimental Research. 14: 695-703. PMID 1702269 DOI: 10.1111/j.1530-0277.1990.tb01229.x |
0.365 |
|
1990 |
Cook RT, Keiner J, Yen A, Fishbaugh J. Ethanol induced growth inhibition and growth adaptation in vitro. Cell cycle delay in late G1. Alcohol and Alcoholism. 25: 33-43. DOI: 10.1093/Oxfordjournals.Alcalc.A044975 |
0.314 |
|
1988 |
Yen A, Freeman L, Fishbaugh J. Induction of HL-60 monocytic cell differentiation promoted by a perturbation of DNA synthesis: hydroxyurea promotes action of TPA. Experimental Cell Research. 174: 98-106. PMID 2826198 DOI: 10.1016/0014-4827(88)90145-0 |
0.366 |
|
1988 |
Guernsey DL, Yen A. Retinoic-acid-induced modulation of c-myc not dependent on its continued presence: possible role in pre-commitment for HL-60 cells. International Journal of Cancer. 42: 576-81. PMID 2459072 DOI: 10.1002/ijc.2910420419 |
0.343 |
|
1987 |
Yen A, Brown D, Fishbaugh J. Precommitment states induced during HL-60 myeloid differentiation: possible similarities of retinoic acid- and DMSO-induced early events. Experimental Cell Research. 173: 80-4. PMID 3678385 DOI: 10.1016/0014-4827(87)90333-8 |
0.379 |
|
1987 |
Yen A, Freeman L, Fishbaugh J. Hydroxyurea indices precommitment during retinoic induced HL-60 terminal myeloid differentiation: possible involvement of gene amplification. Leukemia Research. 11: 63-71. PMID 3468316 DOI: 10.1016/0145-2126(87)90106-8 |
0.374 |
|
1986 |
Yen A, Powers V, Fishbaugh J. Retinoic acid induced HL-60 myeloid differentiation: Dependence of early and late events on isomeric structure Leukemia Research. 10: 619-629. PMID 3458975 DOI: 10.1016/0145-2126(86)90264-X |
0.373 |
|
1986 |
Yen A, Freeman L, Powers V, Van Sant R, Fishbaugh J. Cell cycle dependence of calmodulin levels during HL-60 proliferation and myeloid differentiation. No changes during pre-commitment Experimental Cell Research. 165: 139-151. PMID 2940106 DOI: 10.1016/0014-4827(86)90539-2 |
0.517 |
|
1985 |
Yen A, Reece SL, Albright KL. Control of cell differentiation during proliferation. II. Myeloid differentiation and cell cycle arrest of HL-60 promyelocytes preceded by nuclear structural changes. Leukemia Research. 9: 51-71. PMID 3857406 DOI: 10.1016/0145-2126(85)90021-9 |
0.396 |
|
1984 |
Yen A, Reece SL, Albright KL. Membrane origin for a signal eliciting a program of cell differentiation. Experimental Cell Research. 152: 493-9. PMID 6586426 DOI: 10.1016/0014-4827(84)90651-7 |
0.401 |
|
1984 |
Yen A, Reece SL, Albright KL. Dependence of HL-60 myeloid cell differentiation on continuous and split retinoic acid exposures: precommitment memory associated with altered nuclear structure. Journal of Cellular Physiology. 118: 277-86. PMID 6583206 DOI: 10.1002/jcp.1041180310 |
0.337 |
|
1983 |
Yen A, Lewin D, Fairchild D. Interferon inhibits PWM induced B cell differentiation but not onset of proliferation. Leukemia Research. 6: 221-9. PMID 6985264 DOI: 10.1016/0145-2126(82)90028-5 |
0.321 |
|
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