Andrew Yen - Publications

Affiliations: 
Cornell University, Ithaca, NY, United States 
Area:
Oncology, Cell Biology, Toxicology

100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhu K, Kazim N, Yue J, Yen A. Correction: Vacuolin‑1 enhances RA‑induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP‑76 axis subject to endosomal regulation that drives late differentiation steps. Cell & Bioscience. 13: 22. PMID 36737806 DOI: 10.1186/s13578-023-00965-0  0.311
2022 Zhu K, Kazim N, Yue J, Yen A. Vacuolin-1 enhances RA-induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP-76 axis subject to endosomal regulation that drives late differentiation steps. Cell & Bioscience. 12: 179. PMID 36329484 DOI: 10.1186/s13578-022-00911-6  0.486
2021 Kazim N, Yen A. Evidence of off-target effects of bosutinib that promote retinoic acid-induced differentiation of non-APL AML cells. Cell Cycle (Georgetown, Tex.). 1-14. PMID 34836491 DOI: 10.1080/15384101.2021.2005275  0.537
2021 Kazim N, Yen A. Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells. Oncotarget. 12: 1147-1164. PMID 34136084 DOI: 10.18632/oncotarget.27969  0.531
2020 Zhu K, Yue J, Yen A. Depleting interferon regulatory factor-1(IRF-1) with CRISPR/Cas9 attenuates inducible oxidative metabolism without affecting RA-induced differentiation in HL-60 human AML cells. Faseb Bioadvances. 2: 354-364. PMID 32617521 DOI: 10.1096/fba.2020-00004  0.501
2020 Rashid A, Wang R, Zhang L, Yue J, Yang M, Yen A. Dissecting the novel partners of nuclear c-Raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation. Experimental Cell Research. 111989. PMID 32283065 DOI: 10.1016/J.Yexcr.2020.111989  0.434
2020 Rashid A, Duan X, Gao F, Yang M, Yen A. Roscovitine enhances all- retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation. Oncotarget. 11: 1017-1036. PMID 32256976 DOI: 10.18632/Oncotarget.27508  0.537
2020 Rashid A, Duan X, Gao F, Yang M, Yen A. Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor. Cellular Signalling. 109555. PMID 32032659 DOI: 10.1016/j.cellsig.2020.109555  0.488
2018 Bunaciu RP, MacDonald RJ, Jensen HA, Gao F, Wang X, Johnson L, Varner JD, Yen A. Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML. Leukemia & Lymphoma. 1-12. PMID 30570341 DOI: 10.1080/10428194.2018.1543880  0.396
2018 MacDonald RJ, Yen A. CXCR5 overexpression in HL-60 cells enhances chemotaxis toward CXCL13 without anticipated interaction partners or enhanced MAPK signaling. In Vitro Cellular & Developmental Biology. Animal. PMID 30276608 DOI: 10.1007/s11626-018-0293-z  0.434
2018 MacDonald RJ, Bunaciu RP, Ip V, Dai D, Tran D, Varner JD, Yen A. Src family kinase inhibitor bosutinib enhances retinoic acid-induced differentiation of HL-60 leukemia cells. Leukemia & Lymphoma. 1-11. PMID 29569971 DOI: 10.1080/10428194.2018.1452213  0.445
2018 Supnick HT, Bunaciu RP, Yen A. The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1,25-dihydroxyvitamin D3-induced differentiation of HL-60 myeloblastic leukemia cells. Oncotarget. 9: 9808-9824. PMID 29515772 DOI: 10.18632/Oncotarget.24275  0.338
2018 Bunaciu RP, MacDonald RJ, Gao F, Johnson LM, Varner JD, Wang X, Nataraj S, Guzman ML, Yen A. Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment. Oncotarget. 9: 4134-4149. PMID 29423110 DOI: 10.18632/Oncotarget.23642  0.341
2017 MacDonald RJ, Shrimp JH, Jiang H, Zhang L, Lin H, Yen A. Probing the requirement for CD38 in retinoic acid-induced HL-60 cell differentiation with a small molecule dimerizer and genetic knockout. Scientific Reports. 7: 17406. PMID 29234114 DOI: 10.1038/S41598-017-17720-4  0.459
2017 Tasseff R, Jensen HA, Congleton J, Dai D, Rogers KV, Sagar A, Bunaciu RP, Yen A, Varner JD. An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program. Scientific Reports. 7: 14327. PMID 29085021 DOI: 10.1038/S41598-017-14523-5  0.783
2016 Wallace AS, Supnick HT, Bunaciu RP, Yen A. RRD-251 enhances All-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells. Oncotarget. PMID 27331409 DOI: 10.18632/Oncotarget.10136  0.542
2015 Jensen HA, Yourish HB, Bunaciu RP, Varner JD, Yen A. Induced myelomonocytic differentiation in leukemia cells is accompanied by noncanonical transcription factor expression. Febs Open Bio. 5: 789-800. PMID 26566473 DOI: 10.1016/J.Fob.2015.09.008  0.516
2015 Bunaciu RP, Jensen HA, MacDonald RJ, LaTocha DH, Varner JD, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. Plos One. 10: e0135668. PMID 26287494 DOI: 10.1371/Journal.Pone.0135668  0.543
2015 Ibabao CN, Bunaciu RP, Schaefer DM, Yen A. The AhR agonist VAF347 augments retinoic acid-induced differentiation in leukemia cells. Febs Open Bio. 5: 308-18. PMID 25941627 DOI: 10.1016/J.Fob.2015.04.002  0.618
2015 Jensen HA, Bunaciu RP, Varner JD, Yen A. GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation. Cellular Signalling. 27: 1666-75. PMID 25817574 DOI: 10.1016/J.Cellsig.2015.03.014  0.561
2015 Kim BJ, Zhao S, Bunaciu RP, Yen A, Wu M. A 3D in situ cell counter reveals that breast tumor cell (MDA-MB-231) proliferation rate is reduced by the collagen matrix density. Biotechnology Progress. PMID 25683564 DOI: 10.1002/Btpr.2062  0.35
2015 Wallace AS, Geil WM, Yen A. Abstract 2031: RRD-251 enhances retinoic acid induced differentiation of myeloblastic leukemic cells Cancer Research. 75: 2031-2031. DOI: 10.1158/1538-7445.Am2015-2031  0.497
2014 Jensen HA, Bunaciu RP, Ibabao CN, Myers R, Varner JD, Yen A. Retinoic acid therapy resistance progresses from unilineage to bilineage in HL-60 leukemic blasts. Plos One. 9: e98929. PMID 24922062 DOI: 10.1371/Journal.Pone.0098929  0.519
2014 Congleton J, Shen M, MacDonald R, Malavasi F, Yen A. Phosphorylation of c-Cbl and p85 PI3K driven by all-trans retinoic acid and CD38 depends on Lyn kinase activity. Cellular Signalling. 26: 1589-97. PMID 24686085 DOI: 10.1016/J.Cellsig.2014.03.021  0.794
2014 Shrimp JH, Hu J, Dong M, Wang BS, MacDonald R, Jiang H, Hao Q, Yen A, Lin H. Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe. Journal of the American Chemical Society. 136: 5656-63. PMID 24660829 DOI: 10.1021/Ja411046J  0.436
2014 Geil WM, Yen A. Nuclear Raf-1 kinase regulates the CXCR5 promoter by associating with NFATc3 to drive retinoic acid-induced leukemic cell differentiation. The Febs Journal. 281: 1170-80. PMID 24330068 DOI: 10.1111/Febs.12693  0.568
2013 Bunaciu RP, Yen A. 6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells. Molecular Cancer. 12: 39. PMID 23656719 DOI: 10.1186/1476-4598-12-39  0.501
2013 Jensen HA, Styskal LE, Tasseff R, Bunaciu RP, Congleton J, Varner JD, Yen A. The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells. Plos One. 8: e58621. PMID 23554907 DOI: 10.1371/Journal.Pone.0058621  0.815
2012 Congleton J, MacDonald R, Yen A. Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK-dependent differentiation of myeloid leukemia cells. Leukemia. 26: 1180-8. PMID 22182854 DOI: 10.1038/Leu.2011.390  0.785
2011 Shen M, Bunaciu RP, Congleton J, Jensen HA, Sayam LG, Varner JD, Yen A. Interferon regulatory factor-1 binds c-Cbl, enhances mitogen activated protein kinase signaling and promotes retinoic acid-induced differentiation of HL-60 human myelo-monoblastic leukemia cells. Leukemia & Lymphoma. 52: 2372-9. PMID 21740303 DOI: 10.3109/10428194.2011.603449  0.818
2011 Tasseff R, Nayak S, Song SO, Yen A, Varner JD. Modeling and analysis of retinoic acid induced differentiation of uncommitted precursor cells. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 578-91. PMID 21437295 DOI: 10.1039/C0Ib00141D  0.527
2011 Bunaciu RP, Yen A. Activation of the aryl hydrocarbon receptor AhR Promotes retinoic acid-induced differentiation of myeloblastic leukemia cells by restricting expression of the stem cell transcription factor Oct4. Cancer Research. 71: 2371-80. PMID 21262915 DOI: 10.1158/0008-5472.Can-10-2299  0.547
2011 Congleton J, Jiang H, Malavasi F, Lin H, Yen A. ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary. Experimental Cell Research. 317: 910-9. PMID 21156171 DOI: 10.1016/J.Yexcr.2010.12.003  0.795
2010 Reiterer G, Chen L, Tassef R, Varner JD, Chen CY, Yen A. RAF associates with phosphorylated nuclear BubR1 during endoreduplication induced by JAK inhibition. Cell Cycle (Georgetown, Tex.). 9: 3297-304. PMID 20703093 DOI: 10.4161/Cc.9.16.12631  0.402
2010 Nayak S, Shen M, Bunaciu RP, Bloom SE, Varner JD, Yen A. Arsenic trioxide cooperates with all trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RARalpha negative human myeloblastic leukemia cells. Leukemia & Lymphoma. 51: 1734-47. PMID 20615082 DOI: 10.3109/10428194.2010.501535  0.562
2009 Shen M, Yen A. c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrest. The Journal of Biological Chemistry. 284: 25664-77. PMID 19635790 DOI: 10.1074/Jbc.M109.014241  0.503
2009 Smith J, Bunaciu RP, Reiterer G, Coder D, George T, Asaly M, Yen A. Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells. Experimental Cell Research. 315: 2241-8. PMID 19298812 DOI: 10.1016/J.Yexcr.2009.03.004  0.541
2009 Tallini YN, Greene KS, Craven M, Spealman A, Breitbach M, Smith J, Fisher PJ, Steffey M, Hesse M, Doran RM, Woods A, Singh B, Yen A, Fleischmann BK, Kotlikoff MI. c-kit expression identifies cardiovascular precursors in the neonatal heart. Proceedings of the National Academy of Sciences of the United States of America. 106: 1808-13. PMID 19193854 DOI: 10.1073/Pnas.0808920106  0.382
2009 Jiang H, Congleton J, Liu Q, Merchant P, Malavasi F, Lee HC, Hao Q, Yen A, Lin H. Mechanism-based small molecule probes for labeling CD38 on live cells. Journal of the American Chemical Society. 131: 1658-9. PMID 19191692 DOI: 10.1021/Ja808387G  0.767
2009 Shen M, Yen A. Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells. Oncology. 76: 91-100. PMID 19127080 DOI: 10.1159/000188664  0.567
2008 Shen M, Yen A. c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells. Cancer Research. 68: 8761-9. PMID 18974118 DOI: 10.1158/0008-5472.Can-08-1058  0.608
2008 Kauss MA, Reiterer G, Bunaciu RP, Yen A. Human myeloblastic leukemia cells (HL-60) express a membrane receptor for estrogen that signals and modulates retinoic acid-induced cell differentiation. Experimental Cell Research. 314: 2999-3006. PMID 18692045 DOI: 10.1016/J.Yexcr.2008.07.015  0.536
2008 Reiterer G, Bunaciu RP, Smith JL, Yen A. Inhibiting the platelet derived growth factor receptor increases signs of retinoic acid syndrome in myeloid differentiated HL-60 cells. Febs Letters. 582: 2508-14. PMID 18571505 DOI: 10.1016/J.Febslet.2008.06.016  0.499
2008 Wang J, Yen A. A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. The Journal of Biological Chemistry. 283: 4375-86. PMID 18006504 DOI: 10.1074/Jbc.M708471200  0.564
2007 Reiterer G, Yen A. Platelet-derived growth factor receptor regulates myeloid and monocytic differentiation of HL-60 cells. Cancer Research. 67: 7765-72. PMID 17699781 DOI: 10.1158/0008-5472.Can-07-0014  0.543
2007 Yen A. Retinoic acid therapy served by ligands cross linking and masking CD38. Leukemia Research. 31: 423-5. PMID 16914201 DOI: 10.1016/J.Leukres.2006.07.003  0.359
2006 Reiterer G, Yen A. Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication. Cancer Research. 66: 9083-9. PMID 16982750 DOI: 10.1158/0008-5472.Can-06-0972  0.465
2006 Chikamori K, Hill JE, Grabowski DR, Zarkhin E, Grozav AG, Vaziri SA, Wang J, Gudkov AV, Rybicki LR, Bukowski RM, Yen A, Tanimoto M, Ganapathi MK, Ganapathi R. Downregulation of topoisomerase IIbeta in myeloid leukemia cell lines leads to activation of apoptosis following all-trans retinoic acid-induced differentiation/growth arrest. Leukemia. 20: 1809-18. PMID 16932348 DOI: 10.1038/Sj.Leu.2404351  0.53
2006 Lamkin TJ, Chin V, Yen A. All-trans retinoic acid induces p62DOK1 and p56DOK2 expression which enhances induced differentiation and G0 arrest of HL-60 leukemia cells. American Journal of Hematology. 81: 603-15. PMID 16823827 DOI: 10.1002/Ajh.20667  0.807
2006 Yen A, Varvayanis S, Smith JL, Lamkin TJ. Retinoic acid induces expression of SLP-76: expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells. European Journal of Cell Biology. 85: 117-32. PMID 16439309 DOI: 10.1016/J.Ejcb.2005.09.020  0.804
2006 Lamkin TJ, Chin V, Varvayanis S, Smith JL, Sramkoski RM, Jacobberger JW, Yen A. Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. Journal of Cellular Biochemistry. 97: 1328-38. PMID 16329108 DOI: 10.1002/Jcb.20745  0.81
2006 Ganapathi M, Chikamori K, Hill J, Grabowski D, Zarkhin E, Grozav A, Vaziri S, Bukowski R, Yen A, Ganapathi R. 493 POSTER Down regulation of topoisomerase IIβ in myeloid leukemia cell lines leads to activation of apoptosis following all-trans retinoic acid-induced differentiation/growth arrest European Journal of Cancer Supplements. 4: 150. DOI: 10.1016/S1359-6349(06)70498-0  0.476
2004 Yen A, Lin DM, Lamikin TJ, Varvayanis S. Retinoic acid, bromodeoxyuridine, and the Δ205 mutant polyoma virus middle T antigen regulate expression levels of a common ensemble of proteins associated with early stages of inducing HL-60 leukemic cell differentiation. In Vitro Cellular & Developmental Biology. Animal. 40: 216-41. PMID 27520281 DOI: 10.1290/1543-706X(2004)40<216:Rabatm>2.0.Co;2  0.574
2004 Yen A, Lin DM, Lamkin TJ, Varvayanis S. retinoic acid, bromodeoxyuridine, and the Delta 205 mutant polyoma virus middle T antigen regulate expression levels of a common ensemble of proteins associated with early stages of inducing HL-60 leukemic cell differentiation. In Vitro Cellular & Developmental Biology. Animal. 40: 216-41. PMID 15638704 DOI: 10.1290/1543-706X(2004)40<216:RABATM>2.0.CO;2  0.804
2004 Flaminio MJ, Yen A, Antczak DF. The proliferation inhibitory proteins p27(Kip1) and retinoblastoma are involved in the control of equine lymphocyte proliferation. Veterinary Immunology and Immunopathology. 102: 363-77. PMID 15541790 DOI: 10.1016/J.Vetimm.2004.07.001  0.432
2004 Yen A, Fenning R, Chandraratna R, Walker P, Varvayanis S. A retinoic acid receptor beta/gamma-selective prodrug (tazarotene) plus a retinoid X receptor ligand induces extracellular signal-regulated kinase activation, retinoblastoma hypophosphorylation, G0 arrest, and cell differentiation. Molecular Pharmacology. 66: 1727-37. PMID 15383624 DOI: 10.1124/Mol.104.003475  0.537
2004 Wang J, Yen A. A novel retinoic acid-responsive element regulates retinoic acid-induced BLR1 expression. Molecular and Cellular Biology. 24: 2423-43. PMID 14993281  0.364
2002 Wightman J, Roberson MS, Lamkin TJ, Varvayanis S, Yen A. Retinoic acid-induced growth arrest and differentiation: retinoic acid up-regulates CD32 (Fc gammaRII) expression, the ectopic expression of which retards the cell cycle. Molecular Cancer Therapeutics. 1: 493-506. PMID 12479267  0.811
2002 Battle TE, Yen A. Ectopic expression of CXCR5/BLR1 accelerates retinoic acid- and vitamin D(3)-induced monocytic differentiation of U937 cells. Experimental Biology and Medicine (Maywood, N.J.). 227: 753-62. PMID 12324654 DOI: 10.1177/153537020222700906  0.533
2002 Hong HY, Varvayanis S, Yen A. Retinoic acid causes MEK-dependent RAF phosphorylation through RARalpha plus RXR activation in HL-60 cells. Differentiation; Research in Biological Diversity. 68: 55-66. PMID 11683493 DOI: 10.1046/J.1432-0436.2001.068001055.X  0.477
2001 Yen A, Placanica L, Bloom S, Varvayanis S. Polyomavirus small t antigen prevents retinoic acid-induced retinoblastoma protein hypophosphorylation and redirects retinoic acid-induced G0 arrest and differentiation to apoptosis Journal of Virology. 75: 5302-5314. PMID 11333911 DOI: 10.1128/Jvi.75.11.5302-5314.2001  0.556
2001 Yen A, Norman AW, Varvayanis S. Nongenomic vitamin D3 analogs activating ERK2 in HL-60 cells show that retinoic acid-induced differentiation and cell cycle arrest require early concurrent MAPK and RAR and RXR activation [2] In Vitro Cellular and Developmental Biology - Animal. 37: 93-99. PMID 11332745 DOI: 10.1290/1071-2690(2001)037<0093:Nvdaae>2.0.Co;2  0.487
2001 Battle TE, Roberson MS, Zhang T, Varvayanis S, Yen A. Retinoic acid-induced blr1 expression requires RARalpha, RXR, and MAPK activation and uses ERK2 but not JNK/SAPK to accelerate cell differentiation. European Journal of Cell Biology. 80: 59-67. PMID 11211936 DOI: 10.1078/0171-9335-00141  0.567
2000 Yen A, Varvayanis S. Retinoic acid increases amount of phosphorylated RAF; ectopic expression of cFMS reveals that retinoic acid-induced differentiation is more strongly dependent on ERK2 signaling than induced GO arrest is. In Vitro Cellular & Developmental Biology. Animal. 36: 249-55. PMID 10852350 DOI: 10.1290/1071-2690(2000)036<0249:Raiaop>2.0.Co;2  0.527
2000 Battle TE, Levine RA, Yen A. Retinoic acid-induced blr1 expression promotes ERK2 activation and cell differentiation in HL-60 cells. Experimental Cell Research. 254: 287-98. PMID 10640427 DOI: 10.1006/Excr.1999.4766  0.558
1999 Yen A, Roberson MS, Varvayanis S. Retinoic acid selectively activates the ERK2 but not JNK/SAPK or p38 MAP kinases when inducing myeloid differentiation. In Vitro Cellular & Developmental Biology. Animal. 35: 527-32. PMID 10548434 DOI: 10.1007/S11626-999-0063-Z  0.394
1999 Yen A, Cherington V, Schaffhausen B, Marks K, Varvayanis S. Transformation-defective polyoma middle T antigen mutants defective in PLCgamma, PI-3, or src kinase activation enhance ERK2 activation and promote retinoic acid-induced, cell differentiation like wild-type middle T. Experimental Cell Research. 248: 538-51. PMID 10222145 DOI: 10.1006/Excr.1999.4423  0.482
1999 Townsend KJ, Zhou P, Qian L, Bieszczad CK, Lowrey CH, Yen A, Craig RW. Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation. The Journal of Biological Chemistry. 274: 1801-13. PMID 9880563 DOI: 10.1074/Jbc.274.3.1801  0.444
1998 Yen A, Sturgill R. Hypophosphorylation of the RB protein in S and G2 as well as G1 during growth arrest. Experimental Cell Research. 241: 324-31. PMID 9637774 DOI: 10.1006/Excr.1998.4007  0.354
1998 Platko JD, Forbes ME, Varvayanis S, Williams MN, Brooks SC, Cherington V, Yen A. Polyoma middle T antigen in HL-60 cells accelerates hematopoietic myeloid and monocytic cell differentiation. Experimental Cell Research. 238: 42-50. PMID 9457055 DOI: 10.1006/Excr.1997.3782  0.488
1997 Brooks SC, Sturgill R, Choi J, Yen A. An RXR-selective analog attenuates the RAR alpha-selective analog-induced differentiation and non-G1-restricted growth arrest of NB4 cells. Experimental Cell Research. 234: 259-69. PMID 9260893 DOI: 10.1006/Excr.1997.3620  0.413
1997 Platko JD, Yen A. Paxillin increases as retinoic acid or vitamin D3 induce HL-60 cell differentiation. In Vitro Cellular & Developmental Biology. Animal. 33: 84-7. PMID 9081214 DOI: 10.1007/S11626-997-0027-0  0.409
1997 Yen A, Sturgill R, Varvayanis S, Chern R. FMS (CSF-1 receptor) prolongs cell cycle and promotes retinoic acid-induced hypophosphorylation of retinoblastoma protein, G1 arrest, and cell differentiation. Experimental Cell Research. 229: 111-25. PMID 8940255 DOI: 10.1006/excr.1996.0349  0.478
1996 Yen A, Varvayanis S. The ratio of retinoblastoma (RB) to fos and RB to myc expression during the cell cycle. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 210: 205-12. PMID 8539257 DOI: 10.3181/00379727-210-43940  0.436
1996 Brooks Sr, Kazmer S, Levin A, Yen A. Myeloid differentiation and retinoblastoma phosphorylation changes in HL-60 cells induced by retinoic acid receptor- and retinoid X receptor- selective retinoic acid analogs Blood. 87: 227-237. DOI: 10.1182/Blood.V87.1.227.Bloodjournal871227  0.402
1995 Yen A, Varvayanis S. RB phosphorylation in sodium butyrate-resistant HL-60 cells: cross-resistance to retinoic acid but not vitamin D3. Journal of Cellular Physiology. 163: 502-9. PMID 7775593 DOI: 10.1002/Jcp.1041630310  0.511
1995 Yen A, Varvayanis S. DMSO, sodium butyrate, and TPA induce hypophosphorylation of RB with HL-60 cell differentiation. In Vitro Cellular & Developmental Biology. Animal. 31: 164-7. PMID 7757295 DOI: 10.1007/Bf02639427  0.478
1994 Yen A, Varvayanis S. Late dephosphorylation of the RB protein in G2 during the process of induced cell differentiation. Experimental Cell Research. 214: 250-7. PMID 8082728 DOI: 10.1006/excr.1994.1255  0.391
1994 Yen A, French T, Russell K, Varvayanis S, Forbes M. Vitamin-regulated retinoblastoma tumor suppressor gene expression in leukemic cells. Advances in Experimental Medicine and Biology. 354: 1-18. PMID 8067277 DOI: 10.1007/978-1-4899-0939-8_1  0.373
1994 Yen A, Soong S, Kwon HJ, Yoshida M, Beppu T, Varvayanis S. Enhanced cell differentiation when RB is hypophosphorylated and down-regulated by radicicol, a SRC-kinase inhibitor. Experimental Cell Research. 214: 163-71. PMID 7521842 DOI: 10.1006/excr.1994.1245  0.455
1993 Yen A, Coles M, Varvayanis S. 1,25-Dihydroxy vitamin D3 and 12-O-tetradecanoyl phorbol-13-acetate synergistically induce monocytic cell differentiation: FOS and RB expression. Journal of Cellular Physiology. 156: 198-203. PMID 8314857 DOI: 10.1002/Jcp.1041560126  0.501
1993 Yen A, Forbes ME, Varvayanis S, Tykocinski ML, Groger RK, Platko JD. C-FMS dependent HL-60 cell differentiation and regulation of RB gene expression. Journal of Cellular Physiology. 157: 379-91. PMID 8227169 DOI: 10.1002/jcp.1041570222  0.434
1992 Yen A, Chandler S. Inducers of leukemic cell differentiation cause down-regulation of RB gene expression. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 199: 291-7. PMID 1539032 DOI: 10.3181/00379727-199-43359  0.516
1992 Yen A, Samuel V, Forbes M. Regulation of cell proliferation: Late down-regulation of c-myb preceding myelo-monocytic cell differentiation Journal of Cellular Physiology. 153: 147-156. PMID 1522128 DOI: 10.1002/Jcp.1041530119  0.503
1992 Yen A, Varvayanis S. RB tumor suppressor gene expression responds to DNA synthesis inhibitors. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 669-72. PMID 1429370 DOI: 10.1007/Bf02631044  0.433
1991 Yen A, Chandler S, Sturzenegger-Varvayanis S. Regulated expression of the RB "tumor suppressor gene" in normal lymphocyte mitogenesis: elevated expression in transformed leukocytes and role as a "status quo" gene. Experimental Cell Research. 192: 289-97. PMID 1845796 DOI: 10.1016/0014-4827(91)90188-Z  0.431
1991 Yen A, Blue J, Forbes M. 1,25-Dihydroxy vitamin D2 induces leukemia cell differentiation. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 518-20. PMID 1653778 DOI: 10.1007/Bf02631279  0.373
1990 Mihara K, Cao XR, Yen A, Chandler S, Driscoll B, Murphree AL, T'Ang A, Fung YK. Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product. Science (New York, N.Y.). 246: 1300-3. PMID 2588006 DOI: 10.1126/science.2588006  0.319
1990 Cook RT, Keiner JA, Yen A. Ethanol causes accelerated G1 arrest in differentiating HL-60 cells Alcoholism: Clinical and Experimental Research. 14: 695-703. PMID 1702269 DOI: 10.1111/j.1530-0277.1990.tb01229.x  0.365
1990 Cook RT, Keiner J, Yen A, Fishbaugh J. Ethanol induced growth inhibition and growth adaptation in vitro. Cell cycle delay in late G1. Alcohol and Alcoholism. 25: 33-43. DOI: 10.1093/Oxfordjournals.Alcalc.A044975  0.314
1988 Yen A, Freeman L, Fishbaugh J. Induction of HL-60 monocytic cell differentiation promoted by a perturbation of DNA synthesis: hydroxyurea promotes action of TPA. Experimental Cell Research. 174: 98-106. PMID 2826198 DOI: 10.1016/0014-4827(88)90145-0  0.366
1988 Guernsey DL, Yen A. Retinoic-acid-induced modulation of c-myc not dependent on its continued presence: possible role in pre-commitment for HL-60 cells. International Journal of Cancer. 42: 576-81. PMID 2459072 DOI: 10.1002/ijc.2910420419  0.343
1987 Yen A, Brown D, Fishbaugh J. Precommitment states induced during HL-60 myeloid differentiation: possible similarities of retinoic acid- and DMSO-induced early events. Experimental Cell Research. 173: 80-4. PMID 3678385 DOI: 10.1016/0014-4827(87)90333-8  0.379
1987 Yen A, Freeman L, Fishbaugh J. Hydroxyurea indices precommitment during retinoic induced HL-60 terminal myeloid differentiation: possible involvement of gene amplification. Leukemia Research. 11: 63-71. PMID 3468316 DOI: 10.1016/0145-2126(87)90106-8  0.374
1986 Yen A, Powers V, Fishbaugh J. Retinoic acid induced HL-60 myeloid differentiation: Dependence of early and late events on isomeric structure Leukemia Research. 10: 619-629. PMID 3458975 DOI: 10.1016/0145-2126(86)90264-X  0.373
1986 Yen A, Freeman L, Powers V, Van Sant R, Fishbaugh J. Cell cycle dependence of calmodulin levels during HL-60 proliferation and myeloid differentiation. No changes during pre-commitment Experimental Cell Research. 165: 139-151. PMID 2940106 DOI: 10.1016/0014-4827(86)90539-2  0.517
1985 Yen A, Reece SL, Albright KL. Control of cell differentiation during proliferation. II. Myeloid differentiation and cell cycle arrest of HL-60 promyelocytes preceded by nuclear structural changes. Leukemia Research. 9: 51-71. PMID 3857406 DOI: 10.1016/0145-2126(85)90021-9  0.396
1984 Yen A, Reece SL, Albright KL. Membrane origin for a signal eliciting a program of cell differentiation. Experimental Cell Research. 152: 493-9. PMID 6586426 DOI: 10.1016/0014-4827(84)90651-7  0.401
1984 Yen A, Reece SL, Albright KL. Dependence of HL-60 myeloid cell differentiation on continuous and split retinoic acid exposures: precommitment memory associated with altered nuclear structure. Journal of Cellular Physiology. 118: 277-86. PMID 6583206 DOI: 10.1002/jcp.1041180310  0.337
1983 Yen A, Lewin D, Fairchild D. Interferon inhibits PWM induced B cell differentiation but not onset of proliferation. Leukemia Research. 6: 221-9. PMID 6985264 DOI: 10.1016/0145-2126(82)90028-5  0.321
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