Kenneth R. McLeish - Publications

Affiliations: 
University of Louisville, Louisville, KY, United States 
Area:
Cell Biology, Molecular Biology, Immunology

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kolonics F, Kajdácsi E, Farkas VJ, Veres DS, Khamari D, Kittel Á, Merchant ML, McLeish KR, Lőrincz ÁM, Ligeti E. Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions. Journal of Leukocyte Biology. PMID 32946637 DOI: 10.1002/Jlb.3A0320-210R  0.348
2020 Catz SD, McLeish KR. Therapeutic targeting of neutrophil exocytosis. Journal of Leukocyte Biology. 107: 393-408. PMID 31990103 DOI: 10.1002/Jlb.3Ri0120-645R  0.365
2019 Singel KL, Emmons TR, Khan ANH, Mayor PC, Shen S, Wong JT, Morrell K, Eng KH, Mark J, Bankert RB, Matsuzaki J, Koya RC, Blom AM, McLeish KR, Qu J, et al. Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment. Jci Insight. PMID 30730851 DOI: 10.1172/Jci.Insight.122311  0.303
2018 Caster DJ, Korte EA, Tan M, Barati MT, Tandon S, Creed TM, Salant DJ, Hata JL, Epstein PN, Huang H, Powell DW, McLeish KR. Neutrophil exocytosis induces podocyte cytoskeletal reorganization and proteinuria in experimental glomerulonephritis. American Journal of Physiology. Renal Physiology. PMID 29790391 DOI: 10.1152/Ajprenal.00039.2018  0.376
2017 Korte EA, Caster DJ, Barati MT, Tan M, Zheng S, Berthier CC, Brosius FC, Vieyra MB, Sheehan RM, Kosiewicz M, Wysoczynski M, Gaffney PM, Salant DJ, McLeish KR, Powell DW. ABIN1 determines severity of glomerulonephritis via activation of intrinsic glomerular inflammation. The American Journal of Pathology. PMID 28935578 DOI: 10.1016/J.Ajpath.2017.08.018  0.352
2017 Creed TM, Tandon S, Ward RA, McLeish KR. Endocytosis is required for exocytosis and priming of respiratory burst activity in human neutrophils. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 28638979 DOI: 10.1007/S00011-017-1070-2  0.363
2017 Caster DJ, Powell DW, Miralda I, Ward RA, McLeish KR. Re-Examining Neutrophil Participation in GN. Journal of the American Society of Nephrology : Jasn. PMID 28620081 DOI: 10.1681/Asn.2016121271  0.33
2017 Miralda I, Uriarte SM, McLeish KR. Multiple Phenotypic Changes Define Neutrophil Priming. Frontiers in Cellular and Infection Microbiology. 7: 217. PMID 28611952 DOI: 10.3389/Fcimb.2017.00217  0.326
2017 McLeish KR, Merchant ML, Creed TM, Tandon S, Barati MT, Uriarte SM, Ward RA. Frontline Science: Tumor necrosis factor-α stimulation and priming of human neutrophil granule exocytosis. Journal of Leukocyte Biology. PMID 28096297 DOI: 10.1189/Jlb.3Hi0716-293Rr  0.395
2016 Hobeika L, Barati MT, Caster DJ, McLeish KR, Merchant ML. Characterization of glomerular extracellular matrix by proteomic analysis of laser captured microdissected glomeruli. Kidney International. PMID 27988214 DOI: 10.1016/J.Kint.2016.09.044  0.301
2015 Lőrincz ÁM, Schütte M, Timár CI, Veres DS, Kittel Á, McLeish KR, Merchant ML, Ligeti E. Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytes. Journal of Leukocyte Biology. 98: 583-9. PMID 25986013 DOI: 10.1189/Jlb.3Vma1014-514R  0.332
2015 Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ. Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators. Plos One. 10: e0121637. PMID 25848767 DOI: 10.1371/Journal.Pone.0121637  0.325
2015 Bai J, Tang L, Lomas-Neira J, Chen Y, McLeish KR, Uriarte SM, Chung CS, Ayala A. TAT-SNAP-23 treatment inhibits the priming of neutrophil functions contributing to shock and/or sepsis-induced extra-pulmonary acute lung injury. Innate Immunity. 21: 42-54. PMID 24391146 DOI: 10.1177/1753425913516524  0.333
2014 Arnett E, Vadia S, Nackerman CC, Oghumu S, Satoskar AR, McLeish KR, Uriarte SM, Seveau S. The pore-forming toxin listeriolysin O is degraded by neutrophil metalloproteinase-8 and fails to mediate Listeria monocytogenes intracellular survival in neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 192: 234-44. PMID 24319266 DOI: 10.4049/Jimmunol.1301302  0.3
2013 Uriarte SM, Rane MJ, Merchant ML, Jin S, Lentsch AB, Ward RA, McLeish KR. Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats. Shock (Augusta, Ga.). 39: 286-92. PMID 23364427 DOI: 10.1097/Shk.0B013E318282C9A1  0.369
2013 McLeish KR, Uriarte SM, Tandon S, Creed TM, Le J, Ward RA. Exocytosis of neutrophil granule subsets and activation of prolyl isomerase 1 are required for respiratory burst priming. Journal of Innate Immunity. 5: 277-89. PMID 23363774 DOI: 10.1159/000345992  0.37
2013 Timár CI, Lorincz AM, Csépányi-Kömi R, Vályi-Nagy A, Nagy G, Buzás EI, Iványi Z, Kittel A, Powell DW, McLeish KR, Ligeti E. Antibacterial effect of microvesicles released from human neutrophilic granulocytes. Blood. 121: 510-8. PMID 23144171 DOI: 10.1182/Blood-2012-05-431114  0.318
2012 Liu W, Yan M, Liu Y, McLeish KR, Coleman WG, Rodgers GP. Olfactomedin 4 inhibits cathepsin C-mediated protease activities, thereby modulating neutrophil killing of Staphylococcus aureus and Escherichia coli in mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 2460-7. PMID 22844115 DOI: 10.4049/Jimmunol.1103179  0.31
2011 Luerman GC, Powell DW, Uriarte SM, Cummins TD, Merchant ML, Ward RA, McLeish KR. Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation. Molecular & Cellular Proteomics : McP. 10: M110.001552. PMID 21097543 DOI: 10.1074/Mcp.M110.001552  0.411
2010 Luerman GC, Uriarte SM, Rane MJ, McLeish KR. Application of proteomics to neutrophil biology. Journal of Proteomics. 73: 552-61. PMID 19580889 DOI: 10.1016/J.Jprot.2009.06.013  0.346
2009 Uriarte SM, Jog NR, Luerman GC, Bhimani S, Ward RA, McLeish KR. Counterregulation of clathrin-mediated endocytosis by the actin and microtubular cytoskeleton in human neutrophils. American Journal of Physiology. Cell Physiology. 296: C857-67. PMID 19176760 DOI: 10.1152/Ajpcell.00454.2008  0.398
2009 Uriarte SM, McLeish KR, Ward RA. Anti-proteinase 3 antibodies both stimulate and prime human neutrophils. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 24: 1150-7. PMID 18952697 DOI: 10.1093/Ndt/Gfn580  0.335
2008 Uriarte SM, Powell DW, Luerman GC, Merchant ML, Cummins TD, Jog NR, Ward RA, McLeish KR. Comparison of proteins expressed on secretory vesicle membranes and plasma membranes of human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 180: 5575-81. PMID 18390742 DOI: 10.4049/Jimmunol.180.8.5575  0.301
2007 Jog NR, Jala VR, Ward RA, Rane MJ, Haribabu B, McLeish KR. Heat shock protein 27 regulates neutrophil chemotaxis and exocytosis through two independent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 178: 2421-8. PMID 17277149 DOI: 10.4049/Jimmunol.178.4.2421  0.369
2007 Jog NR, Rane MJ, Lominadze G, Luerman GC, Ward RA, McLeish KR. The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets. American Journal of Physiology. Cell Physiology. 292: C1690-700. PMID 17202227 DOI: 10.1152/Ajpcell.00384.2006  0.307
2006 Barati MT, Rane MJ, Klein JB, McLeish KR. A proteomic screen identified stress-induced chaperone proteins as targets of Akt phosphorylation in mesangial cells. Journal of Proteome Research. 5: 1636-46. PMID 16823971 DOI: 10.1021/Pr0502469  0.377
2005 Lominadze G, Rane MJ, Merchant M, Cai J, Ward RA, McLeish KR. Myeloid-related protein-14 is a p38 MAPK substrate in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 174: 7257-67. PMID 15905572 DOI: 10.4049/Jimmunol.174.11.7257  0.372
2005 Hirano S, Sun X, DeGuzman CA, Ransom RF, McLeish KR, Smoyer WE, Shelden EA, Welsh MJ, Benndorf R. p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli. American Journal of Physiology. Renal Physiology. 288: F1133-43. PMID 15687248 DOI: 10.1152/Ajprenal.00210.2004  0.354
2005 Khundmiri SJ, Dean WL, McLeish KR, Lederer ED. Parathyroid hormone-mediated regulation of Na+-K+-ATPase requires ERK-dependent translocation of protein kinase Calpha. The Journal of Biological Chemistry. 280: 8705-13. PMID 15637080 DOI: 10.1074/Jbc.M408606200  0.337
2005 Powell DW, Pierce WM, McLeish KR. Defining mitogen-activated protein kinase pathways with mass spectrometry-based approaches. Mass Spectrometry Reviews. 24: 847-64. PMID 15619233 DOI: 10.1002/Mas.20044  0.36
2004 Ward RA, McLeish KR. Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure? Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 19: 1702-7. PMID 15150351 DOI: 10.1093/Ndt/Gfh271  0.335
2004 Barati MT, Powell DW, McLeish KR. Proteomic approach to identification of novel kinase substrates in mesangial cells. Contributions to Nephrology. 141: 231-44. PMID 14650236 DOI: 10.1159/000074601  0.303
2003 Coxon PY, Rane MJ, Uriarte S, Powell DW, Singh S, Butt W, Chen Q, McLeish KR. MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils. Cellular Signalling. 15: 993-1001. PMID 14499342 DOI: 10.1016/S0898-6568(03)00074-3  0.404
2003 Powell DW, Rane MJ, Joughin BA, Kalmukova R, Hong JH, Tidor B, Dean WL, Pierce WM, Klein JB, Yaffe MB, McLeish KR. Proteomic identification of 14-3-3ζ as a mitogen-activated protein kinase-activated protein kinase 2 substrate: Role in dimer formation and ligand binding Molecular and Cellular Biology. 23: 5376-5387. PMID 12861023 DOI: 10.1128/Mcb.23.15.5376-5387.2003  0.402
2003 Singh S, Powell DW, Rane MJ, Millard TH, Trent JO, Pierce WM, Klein JB, Machesky LM, McLeish KR. Identification of the p16-Arc subunit of the Arp 2/3 complex as a substrate of MAPK-activated protein kinase 2 by proteomic analysis. The Journal of Biological Chemistry. 278: 36410-7. PMID 12829704 DOI: 10.1074/Jbc.M306428200  0.376
2003 Rane MJ, Pan Y, Singh S, Powell DW, Wu R, Cummins T, Chen Q, McLeish KR, Klein JB. Heat shock protein 27 controls apoptosis by regulating Akt activation. The Journal of Biological Chemistry. 278: 27828-35. PMID 12740362 DOI: 10.1074/Jbc.M303417200  0.363
2003 Chen Q, Powell DW, Rane MJ, Singh S, Butt W, Klein JB, McLeish KR. Akt phosphorylates p47phox and mediates respiratory burst activity in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 170: 5302-8. PMID 12734380 DOI: 10.4049/Jimmunol.170.10.5302  0.395
2002 Powell DW, Rane MJ, Chen Q, Singh S, McLeish KR. Identification of 14-3-3zeta as a protein kinase B/Akt substrate. The Journal of Biological Chemistry. 277: 21639-42. PMID 11956222 DOI: 10.1074/Jbc.M203167200  0.362
2001 Klein JB, Buridi A, Coxon PY, Rane MJ, Manning T, Kettritz R, McLeish KR. Role of extracellular signal-regulated kinase and phosphatidylinositol-3 kinase in chemoattractant and LPS delay of constitutive neutrophil apoptosis. Cellular Signalling. 13: 335-43. PMID 11369515 DOI: 10.1016/S0898-6568(01)00151-6  0.368
2001 Rane MJ, Coxon PY, Powell DW, Webster R, Klein JB, Pierce W, Ping P, McLeish KR. p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils. The Journal of Biological Chemistry. 276: 3517-23. PMID 11042204 DOI: 10.1074/Jbc.M005953200  0.378
2000 Ward RA, Nakamura M, McLeish KR. Priming of the neutrophil respiratory burst involves p38 mitogen-activated protein kinase-dependent exocytosis of flavocytochrome b558-containing granules. The Journal of Biological Chemistry. 275: 36713-9. PMID 10976103 DOI: 10.1074/Jbc.M003017200  0.394
2000 Arthur JM, Lawrence MS, Payne CR, Rane MJ, McLeish KR. The calcium-sensing receptor stimulates JNK in MDCK cells. Biochemical and Biophysical Research Communications. 275: 538-41. PMID 10964699 DOI: 10.1006/Bbrc.2000.3226  0.364
2000 Coxon PY, Rane MJ, Powell DW, Klein JB, McLeish KR. Differential mitogen-activated protein kinase stimulation by Fc gamma receptor IIa and Fc gamma receptor IIIb determines the activation phenotype of human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 164: 6530-7. PMID 10843711 DOI: 10.4049/Jimmunol.164.12.6530  0.381
2000 Rane MJ, Prossnitz ER, Arthur JM, Ward RA, McLeish KR. Deficient homologous desensitization of formyl peptide receptors stably expressed in undifferentiated HL-60 cells. Biochemical Pharmacology. 60: 179-87. PMID 10825462 DOI: 10.1016/S0006-2952(00)00313-0  0.316
2000 Klein JB, Rane MJ, Scherzer JA, Coxon PY, Kettritz R, Mathiesen JM, Buridi A, McLeish KR. Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways. Journal of Immunology (Baltimore, Md. : 1950). 164: 4286-91. PMID 10754327 DOI: 10.4049/Jimmunol.164.8.4286  0.358
1999 Klein JB, McLeish KR, Ward RA. Transplantation, not dialysis, corrects azotemia-dependent priming of the neutrophil oxidative burst. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 33: 483-91. PMID 10070912 DOI: 10.1016/S0272-6386(99)70185-X  0.33
1999 Klein J, Scherzer J, McLeish K, Kettritz R. GM-CSF DELAYS NEUTROPHIL APOPTOSIS BY ACTIVATION OF EXTRACELLULAR SIGNAL-RESPONSE KINASE AND PHOSPHOINOSITIDE 3-KINASE. Transplantation. 67: S264. DOI: 10.1097/00007890-199904150-01056  0.346
1999 Buridi A, McLeish K, Eades D, Klein J. LIPOPOLYSACCHARIDE DELAYS NEUTROPHIL APOPTOSIS BY ACTIVATION OF EXTRACELLULAR SIGNAL-RESPONSE KINASE. Transplantation. 67: S37. DOI: 10.1097/00007890-199904150-00149  0.344
1998 McLeish KR, Knall C, Ward RA, Gerwins P, Coxon PY, Klein JB, Johnson GL. Activation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-alpha and GM-CSF. Journal of Leukocyte Biology. 64: 537-45. PMID 9766635 DOI: 10.1002/Jlb.64.4.537  0.37
1998 McLeish KR, Klein JB, Coxon PY, Head KZ, Ward RA. Bacterial phagocytosis activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in human neutrophils. Journal of Leukocyte Biology. 64: 835-844. DOI: 10.1002/Jlb.64.6.835  0.395
1996 McLeish KR, Klein JB, Lederer ED, Head KZ, Ward RA. Azotemia, TNF alpha, and LPS prime the human neutrophil oxidative burst by distinct mechanisms. Kidney International. 50: 407-16. PMID 8840267 DOI: 10.1038/Ki.1996.330  0.342
1996 Ward R, McLeish KR. Soluble TNF alpha receptors are increased in chronic renal insufficiency and hemodialysis and inhibit neutrophil priming by TNF alpha. Artificial Organs. 20: 390-5. PMID 8725616 DOI: 10.1111/J.1525-1594.1996.Tb04521.X  0.301
1995 Ward RA, McLeish KR. Hemodialysis with cellulose membranes primes the neutrophil oxidative burst. Artificial Organs. 19: 801-7. PMID 8572999 DOI: 10.1111/J.1525-1594.1995.Tb02431.X  0.334
1995 Klein JB, Scherzer JA, Harding G, Jacobs AA, McLeish KR. TNF-alpha stimulates increased plasma membrane guanine nucleotide binding protein activity in polymorphonuclear leukocytes. Journal of Leukocyte Biology. 57: 500-6. PMID 7884323 DOI: 10.1002/Jlb.57.3.500  0.342
1995 Jacobs AA, Huber JL, Ward RA, Klein JB, McLeish KR. Chemoattractant receptor-specific differences in G protein activation rates regulate effector enzyme and functional responses. Journal of Leukocyte Biology. 57: 679-86. PMID 7722425 DOI: 10.1002/Jlb.57.4.679  0.337
1995 Lederer ED, McLeish KR. P2 purinoceptor stimulation attenuates PTH inhibition of phosphate uptake by a G protein-dependent mechanism. The American Journal of Physiology. 269: F309-16. PMID 7573478 DOI: 10.1152/Ajprenal.1995.269.3.F309  0.387
1994 Lederer ED, Jacobs AA, Hoffman JL, Harding GB, Robishaw JD, McLeish KR, Mcleish KR. Role of carboxylmethylation in chemoattractant receptor-stimulated G protein activation and functional responses Biochemical and Biophysical Research Communications. 200: 1604-1614. PMID 8185616 DOI: 10.1006/Bbrc.1994.1635  0.344
1994 McLeish KR, Lederer ED, Klein JB, Hoffman JL. Effect of prenylcysteine analogues on chemoattractant receptor-mediated G protein activation Cellular Signalling. 6: 569-579. PMID 7818993 DOI: 10.1016/0898-6568(94)90011-6  0.362
1993 Schepers TM, McLeish KR. Differential cholera-toxin- and pertussis-toxin-catalysed ADP-ribosylation of G-proteins coupled to formyl-peptide and leukotriene B4 receptors. The Biochemical Journal. 289: 469-73. PMID 8380997 DOI: 10.1042/Bj2890469  0.311
1992 Schepers TM, Klein JB, Feldhoff PW, Dean WL, McLeish KR. Interferon-gamma induces phosphorylation of multiple small-molecular-weight proteins in U937 cells. Journal of Interferon Research. 12: 289-96. PMID 1331258 DOI: 10.1089/Jir.1992.12.289  0.381
1991 McLeish KR, Klein JB, Schepers T, Sonnenfeld G. Modulation of transmembrane signalling in HL-60 granulocytes by tumour necrosis factor-alpha. The Biochemical Journal. 279: 455-60. PMID 1659380 DOI: 10.1042/Bj2790455  0.358
1991 Klein JB, Scherzer JA, McLEISH KR. Interferon-γ Enhances Superoxide Production by HL-60 Cells Stimulated with Multiple Agonists Journal of Interferon Research. 11: 69-74. DOI: 10.1089/Jir.1991.11.69  0.301
1989 Jacobs AA, Ward RA, Wellhausen SR, McLeish KR. Polymorphonuclear leukocyte function during hemodialysis: relationship to complement activation. Nephron. 52: 119-24. PMID 2739846 DOI: 10.1159/000185613  0.33
1989 McLeish KR, Dean WL, Wellhausen SR, Stelzer GT. Role of intracellular calcium in priming of human peripheral blood monocytes by bacterial lipopolysaccharide. Inflammation. 13: 681-92. PMID 2533167 DOI: 10.1007/Bf00914312  0.314
1987 McLeish KR, Wellhausen SR, Dean WL. Biochemical basis of HLA-DR and CR3 modulation on human peripheral blood monocytes by lipopolysaccharide. Cellular Immunology. 108: 242-8. PMID 3038340 DOI: 10.1016/0008-8749(87)90209-7  0.362
1987 McLeish KR, Wellhausen SR, Stelzer GT. Mechanism of prostaglandin E2 inhibition of acute changes in vascular permeability. Inflammation. 11: 279-288. PMID 2820877 DOI: 10.1007/Bf00915833  0.342
1986 McLeish KR, Miller FN, Stelzer GT, Wellhausen SR. Mechanism by which methylprednisolone inhibits acute immune complex-induced changes in vascular permeability. Inflammation. 10: 321-32. PMID 3744476 DOI: 10.1007/Bf00916127  0.327
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