Robert J. Lechleider - Publications

Affiliations: 
Georgetown University Medical Center, Washington, DC, United States 
Area:
Cell Biology

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Sharifi N, Lechleider RJ, Farrar WL. Transforming growth factor-beta receptor III downregulation in prostate cancer: is inhibin B a tumor suppressor in prostate? Journal of Molecular Endocrinology. 39: 329-32. PMID 17975259 DOI: 10.1677/Jme-07-0084  0.408
2007 Lee YH, Kayyali US, Sousa AM, Rajan T, Lechleider RJ, Day RM. Transforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/Src. American Journal of Respiratory Cell and Molecular Biology. 37: 485-93. PMID 17585111 DOI: 10.1165/rcmb.2006-0439OC  0.744
2006 Briones VR, Chen S, Riegel AT, Lechleider RJ. Mechanism of fibroblast growth factor-binding protein 1 repression by TGF-beta. Biochemical and Biophysical Research Communications. 345: 595-601. PMID 16690027 DOI: 10.1016/J.Bbrc.2006.04.052  0.499
2006 Chen S, Crawford M, Day RM, Briones VR, Leader JE, Jose PA, Lechleider RJ. RhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation. The Journal of Biological Chemistry. 281: 1765-70. PMID 16317010 DOI: 10.1074/jbc.M507771200  0.526
2004 Frontelo P, Leader JE, Yoo N, Potocki AC, Crawford M, Kulik M, Lechleider RJ. Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression. Oncogene. 23: 5242-51. PMID 15107829 DOI: 10.1038/sj.onc.1207660  0.63
2004 Chen S, Lechleider RJ. Transforming growth factor-beta-induced differentiation of smooth muscle from a neural crest stem cell line. Circulation Research. 94: 1195-202. PMID 15059931 DOI: 10.1161/01.RES.0000126897.41658.81  0.7
2003 Chen S, Kulik M, Lechleider RJ. Smad proteins regulate transcriptional induction of the SM22alpha gene by TGF-beta. Nucleic Acids Research. 31: 1302-10. PMID 12582250 DOI: 10.1093/Nar/Gkg224  0.822
2002 Lin Y, Martin J, Gruendler C, Farley J, Meng X, Li BY, Lechleider R, Huff C, Kim RH, Grasser WA, Paralkar V, Wang T. A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs). Bmc Cell Biology. 3: 15. PMID 12097147 DOI: 10.1186/1471-2121-3-15  0.391
2001 Lechleider RJ, Ryan JL, Garrett L, Eng C, Deng Cx, Wynshaw-Boris A, Roberts AB. Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion Developmental Biology. 240: 157-167. PMID 11784053 DOI: 10.1006/Dbio.2001.0469  0.524
2001 Verrecchia F, Vindevoghel L, Lechleider RJ, Uitto J, Roberts AB, Mauviel A. Smad3/AP-1 interactions control transcriptional responses to TGF-beta in a promoter-specific manner. Oncogene. 20: 3332-40. PMID 11423983 DOI: 10.1038/sj.onc.1204448  0.695
2001 Parks WT, Frank DB, Huff C, Renfrew Haft C, Martin J, Meng X, de Caestecker MP, McNally JG, Reddi A, Taylor SI, Roberts AB, Wang T, Lechleider RJ. Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases. The Journal of Biological Chemistry. 276: 19332-9. PMID 11279102 DOI: 10.1074/Jbc.M100606200  0.313
2001 Wurthner JU, Frank DB, Felici A, Green HM, Cao Z, Schneider MD, McNally JG, Lechleider RJ, Roberts AB. Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone. The Journal of Biological Chemistry. 276: 19495-502. PMID 11278302 DOI: 10.1074/JBC.M006473200  0.785
2000 Larisch S, Yi Y, Lotan R, Kerner H, Eimerl S, Tony Parks W, Gottfried Y, Birkey Reffey S, de Caestecker MP, Danielpour D, Book-Melamed N, Timberg R, Duckett CS, Lechleider RJ, Steller H, et al. A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. Nature Cell Biology. 2: 915-21. PMID 11146656 DOI: 10.1038/35046566  0.46
2000 de Caestecker MP, Yahata T, Wang D, Parks WT, Huang S, Hill CS, Shioda T, Roberts AB, Lechleider RJ. The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain. The Journal of Biological Chemistry. 275: 2115-22. PMID 10636916 DOI: 10.1074/jbc.275.3.2115  0.449
1999 Xu RH, Lechleider RJ, Shih HM, Hao CF, Sredni D, Roberts AB, Kung Hf. Functional analysis of human Smad1: role of the amino-terminal domain. Biochemical and Biophysical Research Communications. 258: 366-73. PMID 10329393 DOI: 10.1006/BBRC.1999.0598  0.344
1999 Yang X, Letterio JJ, Lechleider RJ, Chen L, Hayman R, Gu H, Roberts AB, Deng C. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. The Embo Journal. 18: 1280-91. PMID 10064594 DOI: 10.1093/emboj/18.5.1280  0.563
1999 Vindevoghel L, Lechleider RJ, Kon A, de Caestecker MP, Uitto J, Roberts AB, Mauviel A. SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta. Proceedings of the National Academy of Sciences of the United States of America. 95: 14769-74. PMID 9843964 DOI: 10.1073/PNAS.95.25.14769  0.722
1998 Shioda T, Lechleider RJ, Dunwoodie SL, Li H, Yahata T, de Caestecker MP, Fenner MH, Roberts AB, Isselbacher KJ. Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator. Proceedings of the National Academy of Sciences of the United States of America. 95: 9785-90. PMID 9707553 DOI: 10.1073/PNAS.95.17.9785  0.491
1998 de Caestecker MP, Parks WT, Frank CJ, Castagnino P, Bottaro DP, Roberts AB, Lechleider RJ. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes & Development. 12: 1587-92. PMID 9620846 DOI: 10.1101/Gad.12.11.1587  0.649
1998 Vindevoghel L, Kon A, Lechleider RJ, Uitto J, Roberts AB, Mauviel A. Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-beta. The Journal of Biological Chemistry. 273: 13053-7. PMID 9582342 DOI: 10.1074/JBC.273.21.13053  0.783
1998 Vindevoghel L, Kon A, Lechleider RJ, Roberts AB, Kouba DJ, Mauviel A. Identification of the first human gene target for the TGF-β/SMAD signaling pathway: COL7A1 Journal of Dermatological Science. 16: S27. DOI: 10.1016/s0923-1811(98)83157-5  0.404
1997 de Caestecker MP, Hemmati P, Larisch-Bloch S, Ajmera R, Roberts AB, Lechleider RJ. Characterization of functional domains within Smad4/DPC4. The Journal of Biological Chemistry. 272: 13690-6. PMID 9153220 DOI: 10.1074/jbc.272.21.13690  0.769
1996 Wang T, Li BY, Danielson PD, Shah PC, Rockwell S, Lechleider RJ, Martin J, Manganaro T, Donahoe PK. The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors. Cell. 86: 435-44. PMID 8756725 DOI: 10.1016/S0092-8674(00)80116-6  0.625
1996 Byers S, Pishvaian M, Crockett C, Peer C, Tozeren A, Sporn M, Anzano M, Lechleider R. Retinoids increase cell-cell adhesion strength, beta-catenin protein stability, and localization to the cell membrane in a breast cancer cell line: a role for serine kinase activity. Endocrinology. 137: 3265-73. PMID 8754749 DOI: 10.1210/endo.137.8.8754749  0.476
1996 Lechleider RJ, de Caestecker MP, Dehejia A, Polymeropoulos MH, Roberts AB. Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1. The Journal of Biological Chemistry. 271: 17617-20. PMID 8663601 DOI: 10.1074/Jbc.271.30.17617  0.804
1992 Jakowlew SB, Lechleider R, Geiser AG, Kim SJ, Santa-Coloma TA, Cubert J, Sporn MB, Roberts AB. Identification and characterization of the chicken transforming growth factor-beta 3 promoter. Molecular Endocrinology (Baltimore, Md.). 6: 1285-98. PMID 1406706 DOI: 10.1210/Mend.6.8.1406706  0.736
1991 Roberts AB, Kim SJ, Noma T, Glick AB, Lafyatis R, Lechleider R, Jakowlew SB, Geiser A, O'Reilly MA, Danielpour D. Multiple forms of TGF-beta: distinct promoters and differential expression. Ciba Foundation Symposium. 157: 7-15; discussion 15-. PMID 1906395  0.787
1991 Lafyatis R, Lechleider R, Roberts AB, Sporn MB. Secretion and transcriptional regulation of transforming growth factor-β3 during myogenesis Molecular and Cellular Biology. 11: 3795-3803. PMID 1710772  0.429
1990 Roberts AB, Kim SJ, Kondaiah P, Jakowlew SB, Denhez F, Glick AB, Geiser AG, Watanabe S, Noma T, Lechleider R. Transcriptional control of expression of the TGF-betas. Annals of the New York Academy of Sciences. 593: 43-50. PMID 2197962 DOI: 10.1111/J.1749-6632.1990.Tb16098.X  0.692
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