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Joe W. Ramos, Ph.D. - Publications

Affiliations: 
2000-2004 Cell Biology and Neuroscience Rutgers University, New Brunswick, New Brunswick, NJ, United States 
 2004- Cancer Center University of Hawai'i at Manoa, Honolulu, HI 
Area:
Cell Biology, Immunology, Cancer Biology
Website:
http://www2.hawaii.edu/~joeramos
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55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yang WS, Caliva MJ, Khadka VS, Tiirikainen M, Matter ML, Deng Y, Ramos JW. RSK1 and RSK2 serine/threonine kinases regulate different transcription programs in cancer. Frontiers in Cell and Developmental Biology. 10: 1015665. PMID 36684450 DOI: 10.3389/fcell.2022.1015665  0.376
2022 Yamaguchi M, Murata T, Ramos JW. Extracellular Regucalcin Suppresses the Growth, Migration, Invasion and Adhesion of Metastatic Human Prostate Cancer Cells. Oncology. PMID 35340010 DOI: 10.1159/000524303  0.363
2021 Caliva MJ, Yang WS, Young-Robbins S, Zhou M, Yoon H, Matter ML, Grimes ML, Conrads T, Ramos JW. Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates α5β1 integrin endocytosis. Scientific Reports. 11: 19830. PMID 34615962 DOI: 10.1038/s41598-021-99348-z  0.416
2021 Ghanem NZ, Matter ML, Ramos JW. Regulation of Leukaemia Associated Rho GEF (LARG/ARHGEF12). Small Gtpases. 1-9. PMID 34304710 DOI: 10.1080/21541248.2021.1951590  0.353
2020 Corpuz AD, Ramos JW, Matter ML. PTRH2: an adhesion regulated molecular switch at the nexus of life, death, and differentiation. Cell Death Discovery. 6: 124. PMID 33298880 DOI: 10.1038/s41420-020-00357-0  0.306
2020 Yamaguchi M, Murata T, Ramos JW. The calcium channel agonist Bay K 8644 promotes the growth of human liver cancer HepG2 cells in vitro: suppression with overexpressed regucalcin. Molecular and Cellular Biochemistry. PMID 32591915 DOI: 10.1007/S11010-020-03795-7  0.38
2019 Li ZW, Sun B, Gong T, Guo S, Zhang J, Wang J, Sugawara A, Jiang M, Yan J, Gurary A, Zhen X, Gao B, Xiao SY, Chen W, Ma C, ... ... Ramos JW, et al. GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Downregulating Expression of GNAI2. Gastroenterology. PMID 30836096 DOI: 10.1053/J.Gastro.2019.02.040  0.317
2018 Elie BT, Fernández-Gallardo J, Curado N, Cornejo MA, Ramos JW, Contel M. Bimetallic titanocene-gold phosphane complexes inhibit invasion, metastasis, and angiogenesis-associated signaling molecules in renal cancer. European Journal of Medicinal Chemistry. 161: 310-322. PMID 30368130 DOI: 10.1016/J.Ejmech.2018.10.034  0.335
2017 Shi GX, Yang WS, Jin L, Matter ML, Ramos JW. RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279389 DOI: 10.1073/Pnas.1708584115  0.539
2017 Greig FH, Kennedy S, Gibson G, Ramos JW, Nixon GF. PEA-15 (Phosphoprotein Enriched in Astrocytes 15) Is a Protective Mediator in the Vasculature and Is Regulated During Neointimal Hyperplasia. Journal of the American Heart Association. 6. PMID 28893763 DOI: 10.1161/Jaha.117.006936  0.49
2017 Shi G, Jin L, Matter ML, Kesari S, Ramos JW. Abstract 1363: RSK2 provokes invasive signaling in glioblastoma through LARG-dependent activation of Rho GTPases Cancer Research. 77: 1363-1363. DOI: 10.1158/1538-7445.Am2017-1363  0.401
2016 Sulzmaier FJ, Young-Robbins S, Jiang P, Geerts D, Prechtl AM, Matter ML, Kesari S, Ramos JW. RSK2 activity mediates glioblastoma invasiveness and is a potential target for new therapeutics. Oncotarget. PMID 27829215 DOI: 10.18632/Oncotarget.13084  0.76
2016 Jorand R, Biswas S, Wakefield DL, Tobin SJ, Golfetto O, Hilton K, Ko M, Ramos JW, Small AR, Chu P, Singh G, Jovanovic-Talisman T. Molecular signatures of mu opioid receptor and somatostatin receptor 2 in pancreatic cancer. Molecular Biology of the Cell. PMID 27682590 DOI: 10.1091/Mbc.E16-06-0427  0.345
2016 Fash DM, Peer CJ, Li Z, Talisman IJ, Hayavi S, Sulzmaier FJ, Ramos JW, Sourbier C, Neckers L, Figg WD, Beutler JA, Chain WJ. Synthesis of a stable and orally bioavailable englerin analogue. Bioorganic & Medicinal Chemistry Letters. PMID 27107948 DOI: 10.1016/J.Bmcl.2016.04.016  0.707
2015 Fernández-Gallardo J, Elie BT, Sadhukha T, Prabha S, Sanaú M, Rotenberg SA, Ramos JW, Contel M. Heterometallic titanium-gold complexes inhibit renal cancer cells in vitro and in vivo. Chemical Science (Royal Society of Chemistry : 2010). 6: 5269-5283. PMID 27213034 DOI: 10.1039/C5Sc01753J  0.382
2015 Griffiths GS, Doe J, Jijiwa M, Van Ry P, Cruz V, de la Vega M, Ramos JW, Burkin DJ, Matter ML. Bit-1 is an essential regulator of myogenic differentiation. Journal of Cell Science. 128: 1707-17. PMID 25770104 DOI: 10.1242/Dev.125765  0.376
2015 Liang Z, Sulzmaier FJ, Yoshida WY, Kelly M, Ramos JW, Williams PG. Neopetrocyclamines A and B, polycyclic diamine alkaloids from the sponge Neopetrosia cf exigua. Journal of Natural Products. 78: 543-7. PMID 25585025 DOI: 10.1021/Np500759R  0.703
2014 Fernández-Gallardo J, Elie BT, Sulzmaier FJ, Sanaú M, Ramos JW, Contel M. Organometallic Titanocene-Gold Compounds as Potential Chemotherapeutics in Renal Cancer. Study of their Protein Kinase Inhibitory Properties. Organometallics. 33: 6669-6681. PMID 25435644 DOI: 10.1021/Om500965K  0.735
2014 Frik M, Martínez A, Elie BT, Gonzalo O, Ramírez de Mingo D, Sanaú M, Sánchez-Delgado R, Sadhukha T, Prabha S, Ramos JW, Marzo I, Contel M. In vitro and in vivo evaluation of water-soluble iminophosphorane ruthenium(II) compounds. A potential chemotherapeutic agent for triple negative breast cancer. Journal of Medicinal Chemistry. 57: 9995-10012. PMID 25409416 DOI: 10.1021/Jm5012337  0.312
2014 Sharma A, Fonseca LL, Rajani C, Yanagida JK, Endo Y, Cline JM, Stone JC, Ji J, Ramos JW, Lorenzo PS. Targeted deletion of RasGRP1 impairs skin tumorigenesis. Carcinogenesis. 35: 1084-91. PMID 24464785 DOI: 10.1093/Carcin/Bgu016  0.35
2014 Prechtl A, Sulzmaier F, Jiang P, Kesari S, Ramos J. Abstract 5007: RSK isoform regulation of migration and invasion in glioblastoma Cancer Research. 74: 5007-5007. DOI: 10.1158/1538-7445.Am2014-5007  0.527
2013 Sulzmaier FJ, Ramos JW. RSK isoforms in cancer cell invasion and metastasis. Cancer Research. 73: 6099-105. PMID 24097826 DOI: 10.1158/0008-5472.Can-13-1087  0.798
2012 Sulzmaier FJ, Li Z, Nakashige ML, Fash DM, Chain WJ, Ramos JW. Englerin a selectively induces necrosis in human renal cancer cells. Plos One. 7: e48032. PMID 23144724 DOI: 10.1371/Journal.Pone.0048032  0.73
2012 Gawecka JE, Young-Robbins SS, Sulzmaier FJ, Caliva MJ, Heikkilä MM, Matter ML, Ramos JW. RSK2 protein suppresses integrin activation and fibronectin matrix assembly and promotes cell migration. The Journal of Biological Chemistry. 287: 43424-37. PMID 23118220 DOI: 10.1074/Jbc.M112.423046  0.793
2012 Sulzmaier F, Opoku-Ansah J, Ramos JW. Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter. Small Gtpases. 3: 173-7. PMID 22694972 DOI: 10.4161/Sgtp.20021  0.773
2012 Gawecka JE, Geerts D, Koster J, Caliva MJ, Sulzmaier FJ, Opoku-Ansah J, Wada RK, Bachmann AS, Ramos JW. PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma. International Journal of Cancer. 131: 1556-68. PMID 22213050 DOI: 10.1002/Ijc.27415  0.782
2012 Sulzmaier FJ, Valmiki MK, Nelson DA, Caliva MJ, Geerts D, Matter ML, White EP, Ramos JW. PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D. Oncogene. 31: 3547-60. PMID 22105357 DOI: 10.1038/Onc.2011.514  0.759
2012 Williams P, Preciado A, Liang Z, Sulzmaier F, Ramos J. Stictamides - Isolation, synthesis, and biological evaluation of cell invasion inhibitors Planta Medica. 78. DOI: 10.1055/S-0032-1320313  0.735
2011 Liang Z, Sorribas A, Sulzmaier FJ, Jiménez JI, Wang X, Sauvage T, Yoshida WY, Wang G, Ramos JW, Williams PG. Stictamides A-C, MMP12 inhibitors containing 4-amino-3-hydroxy-5-phenylpentanoic acid subunits. The Journal of Organic Chemistry. 76: 3635-43. PMID 21500817 DOI: 10.1021/Jo200241H  0.719
2011 Griffiths GS, Grundl M, Leychenko A, Reiter S, Young-Robbins SS, Sulzmaier FJ, Caliva MJ, Ramos JW, Matter ML. Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathway. The Journal of Biological Chemistry. 286: 14713-23. PMID 21383007 DOI: 10.1074/Jbc.M111.228387  0.788
2011 Hunter I, Mascall KS, Ramos JW, Nixon GF. A phospholipase Cγ1-activated pathway regulates transcription in human vascular smooth muscle cells. Cardiovascular Research. 90: 557-64. PMID 21285289 DOI: 10.1093/Cvr/Cvr039  0.46
2010 Gawecka JE, Griffiths GS, Ek-Rylander B, Ramos JW, Matter ML. R-Ras regulates migration through an interaction with filamin A in melanoma cells. Plos One. 5: e11269. PMID 20585650 DOI: 10.1371/Journal.Pone.0011269  0.789
2010 Pastorino S, Renganathan H, Caliva MJ, Filbert EL, Opoku-Ansah J, Sulzmaier FJ, Gawecka JE, Werlen G, Shaw AS, Ramos JW. The death effector domain protein PEA-15 negatively regulates T-cell receptor signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2818-28. PMID 20354143 DOI: 10.1096/Fj.09-144295  0.725
2009 Valmiki MG, Ramos JW. Death effector domain-containing proteins. Cellular and Molecular Life Sciences : Cmls. 66: 814-30. PMID 18989622 DOI: 10.1007/S00018-008-8489-0  0.393
2008 Ramos JW. The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells. The International Journal of Biochemistry & Cell Biology. 40: 2707-19. PMID 18562239 DOI: 10.1016/J.Biocel.2008.04.009  0.541
2007 Vaidyanathan H, Opoku-Ansah J, Pastorino S, Renganathan H, Matter ML, Ramos JW. ERK MAP kinase is targeted to RSK2 by the phosphoprotein PEA-15. Proceedings of the National Academy of Sciences of the United States of America. 104: 19837-42. PMID 18077417 DOI: 10.1073/Pnas.0704514104  0.754
2006 Renault-Mihara F, Beuvon F, Iturrioz X, Canton B, De Bouard S, Léonard N, Mouhamad S, Sharif A, Ramos JW, Junier MP, Chneiweiss H. Phosphoprotein enriched in astrocytes-15 kDa expression inhibits astrocyte migration by a protein kinase C delta-dependent mechanism. Molecular Biology of the Cell. 17: 5141-52. PMID 16987961 DOI: 10.1091/Mbc.E05-11-1072  0.498
2006 Matter ML, Ramos JW. Expression cloning of signaling proteins regulated by cell adhesion. Methods in Molecular Biology (Clifton, N.J.). 341: 155-65. PMID 16799197 DOI: 10.1385/1-59745-113-4:155  0.479
2005 Renganathan H, Vaidyanathan H, Knapinska A, Ramos JW. Phosphorylation of PEA-15 switches its binding specificity from ERK/MAPK to FADD. The Biochemical Journal. 390: 729-35. PMID 15916534 DOI: 10.1042/Bj20050378  0.762
2005 Sur R, Ramos JW. Vanishin is a novel ubiquitinylated death-effector domain protein that blocks ERK activation Biochemical Journal. 387: 315-324. PMID 15537391 DOI: 10.1042/Bj20041713  0.547
2003 Chou FL, Hill JM, Hsieh JC, Pouyssegur J, Brunet A, Glading A, Uberall F, Ramos JW, Werner MH, Ginsberg MH. PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation. The Journal of Biological Chemistry. 278: 52587-97. PMID 14506247 DOI: 10.1074/Jbc.M309322200  0.636
2003 Vaidyanathan H, Ramos JW. RSK2 activity is regulated by its interaction with PEA-15. The Journal of Biological Chemistry. 278: 32367-72. PMID 12796492 DOI: 10.1074/Jbc.M303988200  0.821
2002 Hill JM, Vaidyanathan H, Ramos JW, Ginsberg MH, Werner MH. Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain. The Embo Journal. 21: 6494-504. PMID 12456656 DOI: 10.1093/Emboj/Cdf641  0.793
2002 Ramos JW, Ginsberg M. Expression cloning strategies for the identification of adhesion molecules. Methods in Cell Biology. 69: 209-21. PMID 12070994 DOI: 10.1016/S0091-679X(02)69014-4  0.596
2002 Desai A, Holleran EA, Incardona JP, Weiner O, Aasland R, Weinzierl RO, Ponnambalam V, Slesinger PA, Ramos JW, Matter ML, Benton R, Hukriede N, Tsang M, Guacci V, Heck MM. Cell biology Current Opinion in Cell Biology. 14: 1-9. DOI: 10.1016/S0955-0674(01)00286-1  0.358
2001 Formstecher E, Ramos JW, Fauquet M, Calderwood DA, Hsieh JC, Canton B, Nguyen XT, Barnier JV, Camonis J, Ginsberg MH, Chneiweiss H. PEA-15 Mediates Cytoplasmic Sequestration of ERK MAP Kinase Developmental Cell. 1: 239-250. PMID 11702783 DOI: 10.1016/S1534-5807(01)00035-1  0.645
2001 Matter ML, Ginsberg MH, Ramos JW. Identification of cell signaling molecules by expression cloning Science's Stke : Signal Transduction Knowledge Environment. 2001. PMID 11593050 DOI: 10.1126/Stke.2001.103.Pl9  0.621
2001 Desai A, Holleran EA, Incardona JP, Weiner O, Aasland R, Weinzierl RO, Ponnambalam V, Slesinger PA, Ramos JW, Matter ML, Benton R, Tsang M, Hukriede N. Paper alert: Cell biology Current Opinion in Cell Biology. 13: 513-521. DOI: 10.1016/S0955-0674(00)00244-1  0.333
2000 Ramos JW, Hughes PE, Renshaw MW, Schwartz MA, Formstecher E, Chneiweiss H, Ginsberg MH. Death effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanism. Molecular Biology of the Cell. 11: 2863-72. PMID 10982386 DOI: 10.1091/Mbc.11.9.2863  0.645
2000 Zhang Y, Redina O, Altshuller YM, Yamazaki M, Ramos J, Chneiweiss H, Kanaho Y, Frohman MA. Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them. The Journal of Biological Chemistry. 275: 35224-32. PMID 10926929 DOI: 10.1074/Jbc.M003329200  0.426
1998 Ramos JW, Kojima TK, Hughes PE, Fenczik CA, Ginsberg MH. The death effector domain of PEA-15 is involved in its regulation of integrin activation Journal of Biological Chemistry. 273: 33897-33900. PMID 9852038 DOI: 10.1074/Jbc.273.51.33897  0.632
1997 Fenczik CA, Sethi T, Ramos JW, Hughes PE, Ginsberg MH. Complementation of dominant suppression implicates CD98 in integrin activation Nature. 390: 81-85. PMID 9363894 DOI: 10.1038/36349  0.607
1996 Alfandari D, Ramos J, Clavilier L, DeSimone DW, Darribère T. The RGD-dependent and the Hep II binding domains of fibronectin govern the adhesive behaviors of amphibian embryonic cells Mechanisms of Development. 56: 83-92. PMID 8798149 DOI: 10.1016/0925-4773(96)00513-8  0.771
1996 Ramos JW, DeSimone DW. Xenopus embryonic cell adhesion to fibronectin: Position-specific activation of RGD/synergy site-dependent migratory behavior at gastrulation Journal of Cell Biology. 134: 227-240. PMID 8698817 DOI: 10.1083/Jcb.134.1.227  0.687
1994 Danker K, Hacke H, Ramos J, DeSimone D, Wedlich D. V(+)-fibronectin expression and localization prior to gastrulation in Xenopus laevis embryos. Mechanisms of Development. 44: 155-65. PMID 8155578 DOI: 10.1016/0925-4773(93)90064-5  0.324
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