| Year |
Citation |
Score |
| 2020 |
Thiagalingam S. Epigenetic memory in development and disease: Unraveling the mechanism. Biochimica Et Biophysica Acta. Reviews On Cancer. 188349. PMID 31982403 DOI: 10.1016/J.Bbcan.2020.188349 |
0.336 |
|
| 2020 |
Wong CK, Lambert AW, Ozturk S, Papageorgis P, Lopez D, Shen N, Sen Z, Abdolmaleky HM, Győrffy B, Feng H, Thiagalingam S. Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan. Molecular Cancer Research : McR. PMID 31932471 DOI: 10.1158/1541-7786.Mcr-19-0525 |
0.8 |
|
| 2019 |
Wong CK, Gromisch C, Ozturk S, Papageorgis P, Abdolmaleky HM, Reinhard BM, Thiagalingam A, Thiagalingam S. MicroRNA-4417 is a tumor suppressor and prognostic biomarker for triple-negative breast cancer. Cancer Biology & Therapy. 1-8. PMID 30922194 DOI: 10.1080/15384047.2019.1595285 |
0.774 |
|
| 2019 |
Kalli M, Mpekris F, Wong CK, Panagi M, Ozturk S, Thiagalingam S, Stylianopoulos T, Papageorgis P. Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis. Frontiers in Oncology. 9: 32. PMID 30805303 DOI: 10.3389/Fonc.2019.00032 |
0.819 |
|
| 2018 |
Abdolmaleky HM, Gower AC, Wong CK, Cox JW, Zhang X, Thiagalingam A, Shafa R, Sivaraman V, Zhou JR, Thiagalingam S. Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain laterality/asymmetry in schizophrenia and bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 30468562 DOI: 10.1002/Ajmg.B.32691 |
0.399 |
|
| 2018 |
Wong CK, Zhang S, Reinhard B, Thiagalingam S. Abstract B60: Nanoparticles directed to IL13RA2 for targeted therapy of basal-like breast cancer Cancer Epidemiology, Biomarkers & Prevention. 27. DOI: 10.1158/1538-7755.Disp17-B60 |
0.485 |
|
| 2018 |
Wong C, Thiagalingam S. Abstract P5-07-09: Identification of miRNA biomarkers for early diagnosis of basal-like breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P5-07-09 |
0.411 |
|
| 2016 |
Nohesara S, Ghadirivasfi M, Barati M, Ghasemzadeh MR, Narimani S, Mousavi-Behbahani Z, Joghataei M, Soleimani M, Taban M, Mehrabi S, Thiagalingam S, Abdolmaleky HM. Methamphetamine-induced psychosis is associated with DNA hypomethylation and increased expression of AKT1 and key dopaminergic genes. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27753212 DOI: 10.1002/Ajmg.B.32506 |
0.421 |
|
| 2016 |
Ozturk S, Papageorgis P, Wong CK, Lambert AW, Abdolmaleky HM, Thiagalingam A, Cohen HT, Thiagalingam S. SDPR functions as a metastasis suppressor in breast cancer by promoting apoptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26739564 DOI: 10.1073/Pnas.1514663113 |
0.815 |
|
| 2015 |
Lambert AW, Wong CK, Ozturk S, Papageorgis P, Raghunathan R, Alekseyev Y, Gower AC, Reinhard BM, Abdolmaleky HM, Thiagalingam S. Tumor Cell-Derived Periostin Regulates Cytokines That Maintain Breast Cancer Stem Cells. Molecular Cancer Research : McR. PMID 26507575 DOI: 10.1158/1541-7786.Mcr-15-0079 |
0.803 |
|
| 2015 |
Abdolmaleky HM, Pajouhanfar S, Faghankhani M, Joghataei MT, Mostafavi A, Thiagalingam S. Antipsychotic drugs attenuate aberrant DNA methylation of DTNBP1 (dysbindin) promoter in saliva and post-mortem brain of patients with schizophrenia and Psychotic bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 687-96. PMID 26285059 DOI: 10.1002/Ajmg.B.32361 |
0.374 |
|
| 2015 |
Papageorgis P, Ozturk S, Lambert AW, Neophytou CM, Tzatsos A, Wong CK, Thiagalingam S, Constantinou AI. Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis. Breast Cancer Research : Bcr. 17: 98. PMID 26208975 DOI: 10.1186/S13058-015-0607-Y |
0.8 |
|
| 2015 |
Abdolmaleky HM, Zhou JR, Thiagalingam S. An update on the epigenetics of psychotic diseases and autism. Epigenomics. 7: 427-49. PMID 26077430 DOI: 10.2217/Epi.14.85 |
0.357 |
|
| 2015 |
Papageorgis P, Ozturk S, Lambert AW, Neophytou CM, Tzatsos A, Wong CK, Thiagalingam S, Constantinou AI. Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis Breast Cancer Research. 17. DOI: 10.1186/s13058-015-0607-y |
0.783 |
|
| 2014 |
Abdolmaleky HM, Nohesara S, Ghadirivasfi M, Lambert AW, Ahmadkhaniha H, Ozturk S, Wong CK, Shafa R, Mostafavi A, Thiagalingam S. DNA hypermethylation of serotonin transporter gene promoter in drug naïve patients with schizophrenia. Schizophrenia Research. 152: 373-80. PMID 24411530 DOI: 10.1016/J.Schres.2013.12.007 |
0.64 |
|
| 2013 |
Lambert AW, Ozturk S, Papageorgis P, Abdolmaleky H, Thiagalingam S. Abstract 4890: Periostin signaling regulates breast cancer stem cells. Cancer Research. 73: 4890-4890. DOI: 10.1158/1538-7445.Am2013-4890 |
0.742 |
|
| 2013 |
Lambert A, Ozturk S, Papageorgis P, Abdolmaleky H, Thiagalingam S. Abstract P1-06-13: Periostin controls cytokine production to maintain breast cancer stem cells Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P1-06-13 |
0.743 |
|
| 2012 |
Lambert AW, Ozturk S, Thiagalingam S. Integrin signaling in mammary epithelial cells and breast cancer. Isrn Oncology. 2012: 493283. PMID 22523705 DOI: 10.5402/2012/493283 |
0.713 |
|
| 2012 |
Thiagalingam S. Molecular detection of smad2/smad4 alterations in colorectal tumors. Methods in Molecular Medicine. 50: 149-65. PMID 21318824 DOI: 10.1385/1-59259-084-5:149 |
0.385 |
|
| 2012 |
Lambert AW, Ozturk S, Thiagalingam S. Abstract 5191: Periostin signaling in breast cancer stem cells Cancer Research. 72: 5191-5191. DOI: 10.1158/1538-7445.Am2012-5191 |
0.724 |
|
| 2012 |
Papageorgis P, Thiagalingam S, Constantinou A. 127 Integrating Transcriptomic and Genetic Approaches to Identify Novel Mediators of Breast Cancer Metastasis European Journal of Cancer. 48: S30-S31. DOI: 10.1016/S0959-8049(12)70827-4 |
0.312 |
|
| 2011 |
Abdolmaleky HM, Thiagalingam S. Can the schizophrenia epigenome provide clues for the molecular basis of pathogenesis? Epigenomics. 3: 679-83. PMID 22126286 DOI: 10.2217/Epi.11.94 |
0.336 |
|
| 2011 |
Nohesara S, Ghadirivasfi M, Mostafavi S, Eskandari MR, Ahmadkhaniha H, Thiagalingam S, Abdolmaleky HM. DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder. Journal of Psychiatric Research. 45: 1432-8. PMID 21820670 DOI: 10.1016/J.Jpsychires.2011.06.013 |
0.376 |
|
| 2011 |
Ghadirivasfi M, Nohesara S, Ahmadkhaniha HR, Eskandari MR, Mostafavi S, Thiagalingam S, Abdolmaleky HM. Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 536-45. PMID 21598376 DOI: 10.1002/Ajmg.B.31192 |
0.345 |
|
| 2011 |
Abdolmaleky HM, Yaqubi S, Papageorgis P, Lambert AW, Ozturk S, Sivaraman V, Thiagalingam S. Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder. Schizophrenia Research. 129: 183-90. PMID 21550210 DOI: 10.1016/J.Schres.2011.04.007 |
0.75 |
|
| 2011 |
Papageorgis P, Cheng K, Ozturk S, Gong Y, Lambert AW, Abdolmaleky HM, Zhou JR, Thiagalingam S. Smad4 inactivation promotes malignancy and drug resistance of colon cancer. Cancer Research. 71: 998-1008. PMID 21245094 DOI: 10.1158/0008-5472.Can-09-3269 |
0.798 |
|
| 2010 |
Papageorgis P, Lambert AW, Ozturk S, Gao F, Pan H, Manne U, Alekseyev YO, Thiagalingam A, Abdolmaleky HM, Lenburg M, Thiagalingam S. Smad signaling is required to maintain epigenetic silencing during breast cancer progression. Cancer Research. 70: 968-78. PMID 20086175 DOI: 10.1158/0008-5472.Can-09-1872 |
0.813 |
|
| 2010 |
Thiagalingam S, Lambert AW, Ozturk S, Abdolmaleky HM, Papageorgis P. Abstract 187: Epigenetic memory during breast cancer progression is sustained by Smad signaling pathway Cancer Research. 70: 187-187. DOI: 10.1158/1538-7445.Am10-187 |
0.815 |
|
| 2009 |
Gao F, Ponte JF, Levy M, Papageorgis P, Cook NM, Ozturk S, Lambert AW, Thiagalingam A, Abdolmaleky HM, Sullivan BA, Thiagalingam S. hBub1 negatively regulates p53 mediated early cell death upon mitotic checkpoint activation. Cancer Biology & Therapy. 8: 548-56. PMID 19252416 DOI: 10.4161/Cbt.8.7.7929 |
0.784 |
|
| 2009 |
Gao F, Ponte JF, Papageorgis P, Levy M, Ozturk S, Lambert AW, Pan H, Chinnappan D, Cheng KH, Thiagalingam A, Abdolmaleky HM, Thiagalingam S. hBub1 deficiency triggers a novel p53 mediated early apoptotic checkpoint pathway in mitotic spindle damaged cells. Cancer Biology & Therapy. 8: 627-35. PMID 19242126 DOI: 10.4161/Cbt.8.7.7928 |
0.751 |
|
| 2008 |
Abdolmaleky HM, Zhou JR, Thiagalingam S, Smith CL. Epigenetic and pharmacoepigenomic studies of major psychoses and potentials for therapeutics. Pharmacogenomics. 9: 1809-23. PMID 19072640 DOI: 10.2217/14622416.9.12.1809 |
0.36 |
|
| 2008 |
Abdolmaleky HM, Smith CL, Zhou JR, Thiagalingam S. Epigenetic alterations of the dopaminergic system in major psychiatric disorders. Methods in Molecular Biology (Clifton, N.J.). 448: 187-212. PMID 18370235 DOI: 10.1007/978-1-59745-205-2_9 |
0.384 |
|
| 2008 |
Smith C, Abdolmalkey H, Faraone S, Shafa R, Tsuang M, Thiagalingam S. 280 – Genetic and epigenetic mediated hyperactivity of membrane-bound catechol-o-methyl transferase (MB-COMT) is associated with hypoexpression of DRD1, DRD2 and RELN genes in schizophrenia (SCZ) and bipolar disorder (BD) but not in well controls Schizophrenia Research. 98: 148-149. DOI: 10.1016/J.Schres.2007.12.347 |
0.322 |
|
| 2007 |
Pan H, Gao F, Papageorgis P, Abdolmaleky HM, Faller DV, Thiagalingam S. Aberrant activation of gamma-catenin promotes genomic instability and oncogenic effects during tumor progression. Cancer Biology & Therapy. 6: 1638-43. PMID 18245958 DOI: 10.4161/Cbt.6.10.4904 |
0.766 |
|
| 2006 |
Abdolmaleky HM, Cheng KH, Faraone SV, Wilcox M, Glatt SJ, Gao F, Smith CL, Shafa R, Aeali B, Carnevale J, Pan H, Papageorgis P, Ponte JF, Sivaraman V, Tsuang MT, ... Thiagalingam S, et al. Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Human Molecular Genetics. 15: 3132-45. PMID 16984965 DOI: 10.1093/Hmg/Ddl253 |
0.761 |
|
| 2006 |
Thiagalingam S. A cascade of modules of a network defines cancer progression. Cancer Research. 66: 7379-85. PMID 16885330 DOI: 10.1158/0008-5472.Can-06-0993 |
0.46 |
|
| 2005 |
Abdolmaleky HM, Thiagalingam S, Wilcox M. Genetics and epigenetics in major psychiatric disorders: dilemmas, achievements, applications, and future scope. American Journal of Pharmacogenomics : Genomics-Related Research in Drug Development and Clinical Practice. 5: 149-60. PMID 15952869 DOI: 10.2165/00129785-200505030-00002 |
0.306 |
|
| 2005 |
Russo AL, Thiagalingam A, Pan H, Califano J, Cheng KH, Ponte JF, Chinnappan D, Nemani P, Sidransky D, Thiagalingam S. Differential DNA hypermethylation of critical genes mediates the stage-specific tobacco smoke-induced neoplastic progression of lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2466-70. PMID 15814621 DOI: 10.1158/1078-0432.Ccr-04-1962 |
0.751 |
|
| 2005 |
Pan H, Califano J, Ponte JF, Russo AL, Cheng KH, Thiagalingam A, Nemani P, Sidransky D, Thiagalingam S. Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer. Cancer Research. 65: 1664-9. PMID 15753360 DOI: 10.1158/0008-5472.Can-04-3297 |
0.73 |
|
| 2005 |
Abdolmaleky HM, Cheng KH, Russo A, Smith CL, Faraone SV, Wilcox M, Shafa R, Glatt SJ, Nguyen G, Ponte JF, Thiagalingam S, Tsuang MT. Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 134: 60-6. PMID 15717292 DOI: 10.1002/Ajmg.B.30140 |
0.734 |
|
| 2004 |
Cheng KH, Ponte JF, Thiagalingam S. Elucidation of epigenetic inactivation of SMAD8 in cancer using targeted expressed gene display. Cancer Research. 64: 1639-46. PMID 14996722 DOI: 10.1158/0008-5472.Can-03-2688 |
0.769 |
|
| 2003 |
Thiagalingam S, Cheng KH, Lee HJ, Mineva N, Thiagalingam A, Ponte JF. Histone deacetylases: unique players in shaping the epigenetic histone code. Annals of the New York Academy of Sciences. 983: 84-100. PMID 12724214 DOI: 10.1111/J.1749-6632.2003.Tb05964.X |
0.727 |
|
| 2003 |
Kugathasan S, Cheng K, Johnson NA, Ogawa H, Rafiee P, Binion DG, Thiagalingam S. Inactivation of mucosal SMAD signaling is associated with the progression from early to late Crohn's disease (Cd) Gastroenterology. 124: A313. DOI: 10.1016/S0016-5085(03)81579-2 |
0.688 |
|
| 2002 |
Thiagalingam S, Foy RL, Cheng KH, Lee HJ, Thiagalingam A, Ponte JF. Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: molecular basis of its occurrence. Current Opinion in Oncology. 14: 65-72. PMID 11790983 DOI: 10.1097/00001622-200201000-00012 |
0.72 |
|
| 2002 |
Thiagalingam S, Cheng K, Foy R, Lee H, Chinnappan D, Ponte J. TGFb and its Smad Connection to Cancer Current Genomics. 3: 449-476. DOI: 10.2174/1389202023350291 |
0.306 |
|
| 2001 |
Thiagalingam S, Laken S, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B, Lengauer C. Mechanisms underlying losses of heterozygosity in human colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 98: 2698-702. PMID 11226302 DOI: 10.1073/Pnas.051625398 |
0.355 |
|
| 1998 |
Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B. 14-3-3sigma is a p53-regulated inhibitor of G2/M progression. Molecular Cell. 1: 3-11. PMID 9659898 DOI: 10.1016/S1097-2765(00)80002-7 |
0.364 |
|
| 1997 |
He TC, da Costa LT, Thiagalingam S. Homeosis and polyposis: a tale from the mouse. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 19: 551-5. PMID 9230687 DOI: 10.1002/Bies.950190705 |
0.305 |
|
| 1996 |
Thiagalingam S, Lengauer C, Leach FS, Schutte M, Hahn SA, Overhauser J, Willson JK, Markowitz S, Hamilton SR, Kern SE, Kinzler KW, Vogelstein B. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nature Genetics. 13: 343-6. PMID 8673134 DOI: 10.1038/Ng0796-343 |
0.394 |
|
| 1995 |
Tokino T, Thiagalingam S, el-Deiry WS, Waldman T, Kinzler KW, Vogelstein B. p53 tagged sites from human genomic DNA. Human Molecular Genetics. 3: 1537-42. PMID 7833908 DOI: 10.1093/Hmg/3.9.1537 |
0.332 |
|
| 1995 |
Thiagalingam S, Kinzler KW, Vogelstein B. PAK1, a gene that can regulate p53 activity in yeast. Proceedings of the National Academy of Sciences of the United States of America. 92: 6062-6. PMID 7597081 DOI: 10.1073/Pnas.92.13.6062 |
0.392 |
|
| 1994 |
Pietenpol JA, Tokino T, Thiagalingam S, El-Deiry WS, Kinzler KW, Vogelstein B. Sequence-specific transcriptional activation is essential for growth suppression by p53 Proceedings of the National Academy of Sciences of the United States of America. 91: 1998-2002. PMID 8134338 DOI: 10.1073/Pnas.91.6.1998 |
0.351 |
|
| 1993 |
Oliner JD, Pietenpol JA, Thiagalingam S, Gyuris J, Kinzler KW, Vogelstein B. Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53 Nature. 362: 857-860. PMID 8479525 DOI: 10.1038/362857A0 |
0.329 |
|
| 1992 |
Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW, Vogelstein B. Oncogenic forms of p53 inhibit p53-regulated gene expression Science. 256: 827-830. PMID 1589764 DOI: 10.1126/Science.1589764 |
0.376 |
|
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