| Year |
Citation |
Score |
| 2024 |
Zakrzewski JL, Suh D, Markley JC, Smith OM, King C, Goldberg GL, Jenq R, Holland AM, Grubin J, Cabrera-Perez J, Brentjens RJ, Lu SX, Rizzuto G, Sant'Angelo DB, Riviere I, et al. Author Correction: Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors. Nature Biotechnology. PMID 38531977 DOI: 10.1038/s41587-024-02205-3 |
0.397 |
|
| 2023 |
Li YR, Zúñiga-Pflücker JC. Thymus aging and immune reconstitution, progresses and challenges. Seminars in Immunology. 70: 101837. PMID 37659170 DOI: 10.1016/j.smim.2023.101837 |
0.308 |
|
| 2023 |
Teichman S, Wang H, Lee CR, Mohtashami M, Foerster E, Han J, Trotman-Grant AC, Winer S, Tsui H, Philpott DJ, Zúñiga-Pflücker JC. Recent Thymic Emigrants Require RBPJ-Dependent Notch Signaling to Transition into Functionally Mature Naive T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 37154711 DOI: 10.4049/jimmunol.2300140 |
0.52 |
|
| 2023 |
Golzari-Sorkheh M, Zúñiga-Pflücker JC. Development and Function of FOXP3 + Regulators of Immune Responses. Clinical and Experimental Immunology. PMID 37085947 DOI: 10.1093/cei/uxad048 |
0.317 |
|
| 2022 |
Mohtashami M, Brauer PM, Zúñiga-Pflücker JC. Induction of Human T Cell Development In Vitro with OP9-DL4-7FS Cells Expressing Human Cytokines. Methods in Molecular Biology (Clifton, N.J.). 2580: 249-260. PMID 36374462 DOI: 10.1007/978-1-0716-2740-2_15 |
0.53 |
|
| 2022 |
Yoganathan K, Yan A, Rocha J, Trotman-Grant A, Mohtashami M, Wells L, Zúñiga-Pflücker JC, Anderson MK. Regulation of the Signal-Dependent E Protein HEBAlt Through a YYY Motif Is Required for Progression Through T Cell Development. Frontiers in Immunology. 13: 848577. PMID 35990644 DOI: 10.3389/fimmu.2022.848577 |
0.511 |
|
| 2022 |
Mohtashami M, Li YR, Lee CR, Zúñiga-Pflücker JC. Thymus Reconstitution in Young and Aged Mice Is Facilitated by -Generated Progenitor T Cells. Frontiers in Immunology. 13: 926773. PMID 35874726 DOI: 10.3389/fimmu.2022.926773 |
0.512 |
|
| 2022 |
Thompson PK, Chen ELY, de Pooter RF, Frelin C, Vogel WK, Lee CR, Venables T, Shah DK, Iscove NN, Leid M, Anderson MK, Zúñiga-Pflücker JC. Realization of the T Lineage Program Involves GATA-3 Induction of Bcl11b and Repression of Cdkn2b Expression. Journal of Immunology (Baltimore, Md. : 1950). PMID 35705252 DOI: 10.4049/jimmunol.2100366 |
0.508 |
|
| 2022 |
Wang H, Zúñiga-Pflücker JC. Thymic Microenvironment: Interactions Between Innate Immune Cells and Developing Thymocytes. Frontiers in Immunology. 13: 885280. PMID 35464404 DOI: 10.3389/fimmu.2022.885280 |
0.586 |
|
| 2022 |
Veiga DFT, Tremblay M, Gerby B, Herblot S, Haman A, Gendron P, Lemieux S, Zúñiga-Pflücker JC, Hébert J, Cohen JP, Hoang T. Monoallelic Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia. Frontiers in Immunology. 13: 867443. PMID 35401501 DOI: 10.3389/fimmu.2022.867443 |
0.526 |
|
| 2021 |
Trotman-Grant AC, Mohtashami M, De Sousa Casal J, Martinez EC, Lee D, Teichman S, Brauer PM, Han J, Anderson MK, Zúñiga-Pflücker JC. DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system. Nature Communications. 12: 5023. PMID 34408144 DOI: 10.1038/s41467-021-25245-8 |
0.639 |
|
| 2021 |
Chen ELY, Lee CR, Thompson PK, Wiest DL, Anderson MK, Zúñiga-Pflücker JC. Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo. Cell Reports. 35: 109227. PMID 34107257 DOI: 10.1016/j.celrep.2021.109227 |
0.481 |
|
| 2021 |
Chen ELY, Brauer PM, Martinez EC, Huang X, Yu N, Anderson MK, Li Y, Zúñiga-Pflücker JC. Cutting Edge: TCR-β Selection Is Required at the CD4CD8 Stage of Human T Cell Development. Journal of Immunology (Baltimore, Md. : 1950). PMID 33941655 DOI: 10.4049/jimmunol.2100141 |
0.47 |
|
| 2021 |
Han J, Zúñiga-Pflücker JC. High-Oxygen Submersion Fetal Thymus Organ Cultures Enable FOXN1-Dependent and -Independent Support of T Lymphopoiesis. Frontiers in Immunology. 12: 652665. PMID 33859647 DOI: 10.3389/fimmu.2021.652665 |
0.328 |
|
| 2021 |
Fahl SP, Contreras AV, Verma A, Qiu X, Harly C, Radtke F, Zúñiga-Pflücker JC, Murre C, Xue HH, Sen JM, Wiest DL. The E protein-TCF1 axis controls γδ T cell development and effector fate. Cell Reports. 34: 108716. PMID 33535043 DOI: 10.1016/j.celrep.2021.108716 |
0.516 |
|
| 2021 |
Han J, Zúñiga-Pflücker JC. A 2020 View of Thymus Stromal Cells in T Cell Development. Journal of Immunology (Baltimore, Md. : 1950). 206: 249-256. PMID 33397738 DOI: 10.4049/jimmunol.2000889 |
0.603 |
|
| 2020 |
Singh J, Mohtashami M, Anderson G, Zúñiga-Pflücker JC. Thymic Engraftment by -Derived Progenitor T Cells in Young and Aged Mice. Frontiers in Immunology. 11: 1850. PMID 32973763 DOI: 10.3389/Fimmu.2020.01850 |
0.624 |
|
| 2020 |
Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zúñiga-Pflücker JC, Manley NR. NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development (Cambridge, England). PMID 32467240 DOI: 10.1242/Dev.178988 |
0.528 |
|
| 2020 |
Elsaesser HJ, Mohtashami M, Osokine I, Snell LM, Cunningham CR, Boukhaled GM, McGavern DB, Zúñiga-Pflücker JC, Brooks DG. Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32094187 DOI: 10.1073/Pnas.1913776117 |
0.569 |
|
| 2019 |
Singh J, Chen ELY, Xing Y, Stefanski HE, Blazar BR, Zúñiga-Pflücker JC. Generation and function of progenitor T cells from StemRegenin-1-expanded CD34+ human hematopoietic progenitor cells. Blood Advances. 3: 2934-2948. PMID 31648315 DOI: 10.1182/Bloodadvances.2018026575 |
0.72 |
|
| 2019 |
Chen ELY, Thompson PK, Zúñiga-Pflücker JC. RBPJ-dependent Notch signaling initiates the T cell program in a subset of thymus-seeding progenitors. Nature Immunology. PMID 31636466 DOI: 10.1038/S41590-019-0518-7 |
0.604 |
|
| 2019 |
Zhao B, Yoganathan K, Li L, Lee JY, Zúñiga-Pflücker JC, Love PE. Notch and the pre-TCR coordinate thymocyte proliferation by induction of the SCF subunits Fbxl1 and Fbxl12. Nature Immunology. PMID 31451788 DOI: 10.1038/S41590-019-0469-Z |
0.468 |
|
| 2019 |
Trotman-Grant A, Zúñiga-Pflücker JC. Close Quarters Can Be a Good Fit for Stem Cells to Become T Cells. Cell Stem Cell. 24: 345-347. PMID 30849360 DOI: 10.1016/J.Stem.2019.02.013 |
0.643 |
|
| 2019 |
Benveniste PM, Nakatsugawa M, Nguyen L, Ohashi PS, Hirano N, Zúñiga-Pflücker JC. In vitro-generated MART-1-specific CD8 T cells display a broader T cell receptor repertoire than naïve ex vivo and tumor infiltrating lymphocytes. Immunology and Cell Biology. PMID 30633397 DOI: 10.1111/imcb.12231 |
0.632 |
|
| 2019 |
Benveniste PM, Roy S, Nakatsugawa M, Chen ELY, Nguyen L, Millar DG, Ohashi PS, Hirano N, Adams EJ, Zuniga-Pflucker JC. Generation and molecular recognition of melanoma-associated antigen-specific human gamma delta T cells. Science Immunology. 3. DOI: 10.2210/Pdb6D7G/Pdb |
0.502 |
|
| 2018 |
Benveniste PM, Roy S, Nakatsugawa M, Chen ELY, Nguyen L, Millar DG, Ohashi PS, Hirano N, Adams EJ, Zúñiga-Pflücker JC. Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells. Science Immunology. 3. PMID 30552102 DOI: 10.1126/Sciimmunol.Aav4036 |
0.55 |
|
| 2018 |
Zhao FL, Ahn JJ, Chen E, Yi TJ, Stickle NH, Spaner D, Zúñiga-Pflücker JC, Dunn SE. Peroxisome Proliferator-Activated Receptor-δ Supports the Metabolic Requirements of Cell Growth in TCRβ-Selected Thymocytes and Peripheral CD4 T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 30257885 DOI: 10.4049/Jimmunol.1800374 |
0.658 |
|
| 2018 |
Singh J, Zúñiga-Pflücker JC. Producing proT-cells to promote immunotherapies. International Immunology. PMID 30102361 DOI: 10.1093/Intimm/Dxy051 |
0.643 |
|
| 2018 |
Krishnamoorthy M, Buhari FHM, Zhao T, Brauer PM, Burrows K, Cao EY, Moxley-Paquette V, Mortha A, Zúñiga-Pflücker JC, Treanor B. The ion channel TRPM7 is required for B cell lymphopoiesis. Science Signaling. 11. PMID 29871911 DOI: 10.1126/Scisignal.Aan2693 |
0.415 |
|
| 2018 |
Zarin P, In TSH, Chen ELY, Singh J, Wong GW, Mohtashami M, Wiest DL, Anderson MK, Zúñiga-Pflücker JC. Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse γδ T Cell Effector Differentiation. Immunology and Cell Biology. PMID 29754419 DOI: 10.1111/Imcb.12164 |
0.476 |
|
| 2018 |
Wu CM, Roth TL, Baglaenko Y, Ferri DM, Brauer P, Zuniga-Pflucker JC, Rosbe KW, Wither JE, Marson A, Allen CDC. Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins. Journal of Immunological Methods. PMID 29614266 DOI: 10.1016/J.Jim.2018.03.009 |
0.393 |
|
| 2018 |
Fahl SP, Coffey F, Kain L, Zarin P, Dunbrack RL, Teyton L, Zúñiga-Pflücker JC, Kappes DJ, Wiest DL. Role of a selecting ligand in shaping the murine γδ-TCR repertoire. Proceedings of the National Academy of Sciences of the United States of America. PMID 29432160 DOI: 10.1073/Pnas.1718328115 |
0.556 |
|
| 2018 |
Stefanski H, Singh J, Norris B, Schumacher R, Wagner JE, Blazar BR, Zuniga-Pflucker JC. Robust Progenitor T-Cell Production From Human Hematopoietic Progenitor Cell Expanded with Stemregenin-1 Biology of Blood and Marrow Transplantation. 24. DOI: 10.1016/J.Bbmt.2017.12.434 |
0.637 |
|
| 2017 |
Falkenhagen A, Singh J, Asad S, Leontyev D, Read S, Zúñiga-Pflücker JC, Joshi S. Control of HIV Infection In Vivo Using Gene Therapy with a Secreted Entry Inhibitor. Molecular Therapy. Nucleic Acids. 9: 132-144. PMID 29246292 DOI: 10.1016/J.Omtn.2017.08.017 |
0.439 |
|
| 2017 |
In TSH, Trotman-Grant A, Fahl S, Chen ELY, Zarin P, Moore AJ, Wiest DL, Zúñiga-Pflücker JC, Anderson MK. HEB is required for the specification of fetal IL-17-producing γδ T cells. Nature Communications. 8: 2004. PMID 29222418 DOI: 10.1038/S41467-017-02225-5 |
0.624 |
|
| 2017 |
Moore AJ, In TS, Trotman-Grant A, Yoganathan K, Montpellier B, Guidos CJ, Zúñiga-Pflücker JC, Anderson MK. A key role for IL-7R in the generation of microenvironments required for thymic dendritic cells. Immunology and Cell Biology. PMID 28890536 DOI: 10.1038/Icb.2017.74 |
0.481 |
|
| 2017 |
Li Y, Brauer PM, Singh J, Xhiku S, Yoganathan K, Zúñiga-Pflücker JC, Anderson MK. Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis. Stem Cell Reports. PMID 28803914 DOI: 10.1016/J.Stemcr.2017.07.011 |
0.495 |
|
| 2017 |
Shen Q, Cohen B, Zheng W, Rahbar R, Martin B, Murakami K, Lamorte S, Thompson P, Berman H, Zúñiga-Pflücker JC, Ohashi PS, Reedijk M. Notch Shapes the Innate Immunophenotype in Breast Cancer. Cancer Discovery. PMID 28790030 DOI: 10.1158/2159-8290.Cd-17-0037 |
0.326 |
|
| 2017 |
Rahman N, Brauer PM, Ho L, Usenko T, Tewary M, Zúñiga-Pflücker JC, Zandstra PW. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence. Nature Communications. 8: 15380. PMID 28541275 DOI: 10.1038/Ncomms15380 |
0.527 |
|
| 2017 |
Smith MJ, Reichenbach DK, Parker SL, Riddle MJ, Mitchell J, Osum KC, Mohtashami M, Stefanski HE, Fife BT, Bhandoola A, Hogquist KA, Holländer GA, Zúñiga-Pflücker JC, Tolar J, Blazar BR. T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction. Jci Insight. 2. PMID 28515359 DOI: 10.1172/Jci.Insight.92056 |
0.599 |
|
| 2017 |
Shukla S, Langley MA, Singh J, Edgar JM, Mohtashami M, Zúñiga-Pflücker JC, Zandstra PW. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1. Nature Methods. PMID 28394335 DOI: 10.1038/Nmeth.4258 |
0.717 |
|
| 2017 |
Volpi S, Yamazaki Y, Brauer PM, van Rooijen E, Hayashida A, Slavotinek A, Sun Kuehn H, Di Rocco M, Rivolta C, Bortolomai I, Du L, Felgentreff K, Ott de Bruin L, Hayashida K, Freedman G, et al. EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. The Journal of Experimental Medicine. PMID 28148688 DOI: 10.1084/Jem.20161525 |
0.443 |
|
| 2017 |
Hao Z, Sheng Y, Duncan GS, Li WY, Dominguez C, Sylvester J, Su YW, Lin GH, Snow BE, Brenner D, You-Ten A, Haight J, Inoue S, Wakeham A, Elford A, et al. K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression. Nature Communications. 8: 14003. PMID 28084302 DOI: 10.1038/Ncomms14003 |
0.555 |
|
| 2016 |
Brauer PM, Singh J, Xhiku S, Zúñiga-Pflücker JC. T Cell Genesis: In Vitro Veritas Est? Trends in Immunology. PMID 27789110 DOI: 10.1016/J.It.2016.09.008 |
0.654 |
|
| 2016 |
Brauer PM, Pessach IM, Clarke E, Rowe JH, Ott de Bruin L, Lee YN, Dominguez-Brauer C, Comeau AM, Awong G, Felgentreff K, Zhang YH, Bredemeyer A, Al-Herz W, Du L, Ververs F, et al. Modeling altered T-cell development with human induced pluripotent stem cells from patients with RAG1 mutations and distinct immunological phenotypes. Blood. PMID 27301863 DOI: 10.1182/Blood-2015-10-676304 |
0.837 |
|
| 2016 |
Mohtashami M, Zarin P, Zúñiga-Pflücker JC. Induction of T Cell Development In Vitro by Delta-Like (Dll)-Expressing Stromal Cells. Methods in Molecular Biology (Clifton, N.J.). 1323: 159-67. PMID 26294407 DOI: 10.1007/978-1-4939-2809-5_14 |
0.671 |
|
| 2015 |
Smith MJ, Webber BR, Mohtashami M, Stefanski HE, Zún˜iga-Pflücker JC, Blazar BR. Concise Review: In Vitro T-Cell Generation from Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination. Stem Cells (Dayton, Ohio). PMID 26227158 DOI: 10.1002/Stem.2115 |
0.683 |
|
| 2015 |
Zúñiga-Pflücker JC. T cell development runs marrow deep. Journal of Experimental Medicine. 212: 599-600. PMID 25941319 DOI: 10.1084/Jem.2125Insight3 |
0.619 |
|
| 2015 |
Liang HC, Zúñiga-Pflücker JC. Hematopoiesis: from start to immune reconstitution potential. Stem Cell Research & Therapy. 6: 52. PMID 25889009 DOI: 10.1186/S13287-015-0051-Z |
0.487 |
|
| 2015 |
Zarin P, Chen EL, In TS, Anderson MK, Zúñiga-Pflücker JC. Gamma delta T-cell differentiation and effector function programming, TCR signal strength, when and how much? Cellular Immunology. 296: 70-5. PMID 25866401 DOI: 10.1016/J.Cellimm.2015.03.007 |
0.612 |
|
| 2015 |
Allan DS, Kirkham CL, Aguilar OA, Qu LC, Chen P, Fine JH, Serra P, Awong G, Gommerman JL, Zúñiga-Pflücker JC, Carlyle JR. An in vitro model of innate lymphoid cell function and differentiation. Mucosal Immunology. 8: 340-51. PMID 25138665 DOI: 10.1038/Mi.2014.71 |
0.795 |
|
| 2015 |
Zúñiga-Pflücker JC. From stem cells to T cells, in vitro applications and in vivo implications Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.026 |
0.642 |
|
| 2014 |
Kianizad K, Zúñiga-Pflücker JC. Dedicated mTEC Progenitors Stay True, Even into Adulthood Immunity. 41: 675-676. PMID 25517607 DOI: 10.1016/J.Immuni.2014.11.008 |
0.402 |
|
| 2014 |
Garabatos N, Blanco J, Fandos C, Lopez E, Santamaria P, Ruiz A, Perez-Vidakovics ML, Benveniste P, Galkin O, Zuñiga-Pflucker JC, Serra P. A monoclonal antibody against the extracellular domain of mouse and human epithelial V-like antigen 1 reveals a restricted expression pattern among CD4- CD8- thymocytes. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33: 305-11. PMID 25357997 DOI: 10.1089/Mab.2014.0030 |
0.489 |
|
| 2014 |
Ku?erová-Levisohn M, Lovett J, Lahiji A, Holmes R, Zúñiga-Pflücker JC, Ortiz BD. Derivation of T cells in vitro from mouse embryonic stem cells. Journal of Visualized Experiments : Jove. e52119. PMID 25349888 DOI: 10.3791/52119 |
0.56 |
|
| 2014 |
Soh CL, Giudice A, Jenny RA, Elliott DA, Hatzistavrou T, Micallef SJ, Kianizad K, Seach N, Zúñiga-Pflücker JC, Chidgey AP, Trounson A, Nilsson SK, Haylock DN, Boyd RL, Elefanty AG, et al. FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors. Stem Cell Reports. 2: 925-37. PMID 24936476 DOI: 10.1016/J.Stemcr.2014.04.009 |
0.574 |
|
| 2014 |
Zúñiga-Pflücker J. New role identified for LRR-containing proteins in T cell development Journal of Experimental Medicine. 211: 746-747. PMID 24799532 DOI: 10.1084/Jem.2115Insight4 |
0.373 |
|
| 2014 |
Shah DK, Zúñiga-Pflücker JC. An Overview of the Intrathymic Intricacies of T Cell Development Journal of Immunology. 192: 4017-4023. PMID 24748636 DOI: 10.4049/Jimmunol.1302259 |
0.633 |
|
| 2014 |
Zarin P, Wong GW, Mohtashami M, Wiest DL, Zúñiga-Pflücker JC. Enforcement of γδ-lineage commitment by the pre-T-cell receptor in precursors with weak γδ-TCR signals. Proceedings of the National Academy of Sciences of the United States of America. 111: 5658-63. PMID 24706811 DOI: 10.1073/Pnas.1312872111 |
0.642 |
|
| 2014 |
Benveniste P, Serra P, Dervovic D, Herer E, Knowles G, Mohtashami M, Zúñiga-Pflücker JC. Notch signals are required for in vitro but not in vivo maintenance of human hematopoietic stem cells and delay the appearance of multipotent progenitors. Blood. 123: 1167-77. PMID 24363404 DOI: 10.1182/Blood-2013-07-505099 |
0.56 |
|
| 2014 |
Ichim CV, Dervović DD, Zúñiga-Pflücker JC, Wells RA. The orphan nuclear receptor Ear-2 (Nr2f6) is a novel negative regulator of T cell development. Experimental Hematology. 42: 46-58. PMID 24096122 DOI: 10.1016/J.Exphem.2013.09.010 |
0.61 |
|
| 2013 |
Awong G, Singh J, Mohtashami M, Malm M, La Motte-Mohs RN, Benveniste PM, Serra P, Herer E, van den Brink MR, Zúñiga-Pflücker JC. Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture. Blood. 122: 4210-9. PMID 24215033 DOI: 10.1182/Blood-2012-12-472803 |
0.872 |
|
| 2013 |
Mohtashami M, Shah DK, Kianizad K, Awong G, Zúñiga-Pflücker JC. Induction of T-cell development by Delta-like 4-expressing fibroblasts. International Immunology. 25: 601-11. PMID 23988616 DOI: 10.1093/Intimm/Dxt027 |
0.881 |
|
| 2013 |
Smeets MF, Mackenzie-Kludas C, Mohtashami M, Zhang HH, Zúñiga-Pflücker JC, Izon DJ. Removal of myeloid cytokines from the cellular environment enhances T-cell development in vitro. International Immunology. 25: 589-99. PMID 23988615 DOI: 10.1093/Intimm/Dxt025 |
0.652 |
|
| 2013 |
Frelin C, Herrington R, Janmohamed S, Barbara M, Tran G, Paige CJ, Benveniste P, Zuñiga-Pflücker JC, Souabni A, Busslinger M, Iscove NN. GATA-3 regulates the self-renewal of long-term hematopoietic stem cells. Nature Immunology. 14: 1037-44. PMID 23974957 DOI: 10.1038/Ni.2692 |
0.496 |
|
| 2013 |
Dervovic DD, Liang HC, Cannons JL, Elford AR, Mohtashami M, Ohashi PS, Schwartzberg PL, Zúñiga-Pflücker JC. Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for Notch. Journal of Immunology (Baltimore, Md. : 1950). 191: 1704-15. PMID 23851691 DOI: 10.4049/Jimmunol.1300417 |
0.855 |
|
| 2013 |
Liang HC, Holmes R, Zúñiga-Pflücker JC. Directed differentiation of embryonic stem cells to the T-lymphocyte lineage. Methods in Molecular Biology (Clifton, N.J.). 1029: 119-28. PMID 23756946 DOI: 10.1007/978-1-62703-478-4_9 |
0.68 |
|
| 2013 |
Awong G, Zúñiga-Pflücker JC. Generation, isolation, and engraftment of in vitro-derived human T cell progenitors. Methods in Molecular Biology (Clifton, N.J.). 946: 103-13. PMID 23179828 DOI: 10.1007/978-1-62703-128-8_7 |
0.837 |
|
| 2012 |
Kennedy M, Awong G, Sturgeon CM, Ditadi A, LaMotte-Mohs R, Zúñiga-Pflücker JC, Keller G. T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures. Cell Reports. 2: 1722-35. PMID 23219550 DOI: 10.1016/J.Celrep.2012.11.003 |
0.839 |
|
| 2012 |
Shah DK, Mohtashami M, Zúñiga-Pflücker JC. Role of recycling, Mindbomb1 association, and exclusion from lipid rafts of δ-like 4 for effective Notch signaling to drive T cell development. Journal of Immunology (Baltimore, Md. : 1950). 189: 5797-808. PMID 23162128 DOI: 10.4049/Jimmunol.1202469 |
0.595 |
|
| 2012 |
Zúñiga-Pflücker JC. When Three Negatives Made a Positive Influence in Defining Four Early Steps in T Cell Development Journal of Immunology. 189: 4201-4202. PMID 23087424 DOI: 10.4049/Jimmunol.1202553 |
0.524 |
|
| 2012 |
Dervovic DD, Ciofani M, Kianizad K, Zúñiga-Pflücker JC. Comparative and functional evaluation of in vitro generated to ex vivo CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 3411-20. PMID 22925927 DOI: 10.4049/Jimmunol.1200979 |
0.849 |
|
| 2012 |
Weinacht KG, Brauer PM, Felgentreff K, Devine A, Gennery AR, Giliani S, Al-Herz W, Schambach A, Zúñiga-Pflücker JC, Notarangelo LD. The role of induced pluripotent stem cells in research and therapy of primary immunodeficiencies. Current Opinion in Immunology. 24: 617-24. PMID 22841347 DOI: 10.1016/J.Coi.2012.07.001 |
0.482 |
|
| 2012 |
Parietti V, Nelson E, Telliam G, Le Noir S, Pla M, Delord M, Vanneaux V, Mohtashami M, Macintyre EA, Gluckman JC, Asnafi V, Zúñiga-Pflücker JC, Larghero J, Canque B. Dynamics of human prothymocytes and xenogeneic thymopoiesis in hematopoietic stem cell-engrafted nonobese diabetic-SCID/IL-2rγnull mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 1648-60. PMID 22798679 DOI: 10.4049/Jimmunol.1201251 |
0.55 |
|
| 2012 |
Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, et al. IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature. 488: 656-9. PMID 22763442 DOI: 10.1038/Nature11323 |
0.344 |
|
| 2012 |
Wong GW, Knowles GC, Mak TW, Ferrando AA, Zúñiga-Pflücker JC. HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes. Blood. 120: 1439-48. PMID 22649105 DOI: 10.1182/Blood-2011-12-395319 |
0.384 |
|
| 2012 |
Shah DK, Zúñiga-Pflücker JC. Notch receptor-ligand interactions during T cell development, a ligand endocytosis-driven mechanism. Current Topics in Microbiology and Immunology. 360: 19-46. PMID 22581027 DOI: 10.1007/82_2012_225 |
0.499 |
|
| 2012 |
Moore AJ, Sarmiento J, Mohtashami M, Braunstein M, Zúñiga-Pflücker JC, Anderson MK. Transcriptional priming of intrathymic precursors for dendritic cell development. Development (Cambridge, England). 139: 373-84. PMID 22186727 DOI: 10.1242/Dev.069344 |
0.527 |
|
| 2011 |
Thompson PK, Zúñiga-Pflücker JC. On becoming a T cell, a convergence of factors kick it up a Notch along the way. Seminars in Immunology. 23: 350-359. PMID 21981947 DOI: 10.1016/J.Smim.2011.08.007 |
0.616 |
|
| 2011 |
Awong G, Zuniga-Pflucker JC. Thymus-bound: the many features of T cell progenitors. Frontiers in Bioscience (Scholar Edition). 3: 961-9. PMID 21622245 DOI: 10.2741/200 |
0.836 |
|
| 2011 |
Awong G, Herer E, La Motte-Mohs RN, Zúñiga-Pflücker JC. Human CD8 T cells generated in vitro from hematopoietic stem cells are functionally mature. Bmc Immunology. 12: 22. PMID 21429219 DOI: 10.1186/1471-2172-12-22 |
0.874 |
|
| 2011 |
Beaudette-Zlatanova BC, Knight KL, Zhang S, Stiff PJ, Zúñiga-Pflücker JC, Le PT. A human thymic epithelial cell culture system for the promotion of lymphopoiesis from hematopoietic stem cells. Experimental Hematology. 39: 570-9. PMID 21296124 DOI: 10.1016/J.Exphem.2011.01.014 |
0.525 |
|
| 2010 |
Murata A, Okuyama K, Sakano S, Kajiki M, Hirata T, Yagita H, Zúñiga-Pflücker JC, Miyake K, Akashi-Takamura S, Moriwaki S, Niida S, Yoshino M, Hayashi S. A Notch Ligand, Delta-Like 1 Functions As an Adhesion Molecule for Mast Cells Journal of Immunology. 185: 3905-3912. PMID 20810995 DOI: 10.4049/Jimmunol.1000195 |
0.4 |
|
| 2010 |
Ciofani M, Zúñiga-Pflücker JC. Determining γδ versus αβ T cell development Nature Reviews Immunology. 10: 657-663. PMID 20725107 DOI: 10.1038/Nri2820 |
0.657 |
|
| 2010 |
Awong G, LaMotte-Mohs R, Zúñiga-Pflücker JC. Key players for T-cell regeneration. Current Opinion in Hematology. 17: 327-32. PMID 20571395 DOI: 10.1097/Moh.0B013E3283395133 |
0.825 |
|
| 2010 |
Mohtashami M, Shah DK, Nakase H, Kianizad K, Petrie HT, Zúñiga-Pflücker JC. Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes. Journal of Immunology (Baltimore, Md. : 1950). 185: 867-76. PMID 20548034 DOI: 10.4049/Jimmunol.1000782 |
0.619 |
|
| 2010 |
Allan DS, Rybalov B, Awong G, Zúñiga-Pflücker JC, Kopcow HD, Carlyle JR, Strominger JL. TGF-β affects development and differentiation of human natural killer cell subsets. European Journal of Immunology. 40: 2289-95. PMID 20540115 DOI: 10.1002/Eji.200939910 |
0.812 |
|
| 2010 |
Dervović D, Zúñiga-Pflücker JC. Positive selection of T cells, an in vitro view Seminars in Immunology. 22: 276-286. PMID 20537907 DOI: 10.1016/J.Smim.2010.04.014 |
0.811 |
|
| 2010 |
Wong GW, Zúñiga-Pflücker JC. gammadelta and alphabeta T cell lineage choice: resolution by a stronger sense of being. Seminars in Immunology. 22: 228-36. PMID 20466561 DOI: 10.1016/J.Smim.2010.04.005 |
0.59 |
|
| 2010 |
Staron M, Yang Y, Liu B, Li J, Shen Y, Zúñiga-Pflücker JC, Aguila HL, Goldschneider I, Li Z. gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis. Blood. 115: 2380-90. PMID 19965672 DOI: 10.1182/Blood-2009-07-233031 |
0.552 |
|
| 2010 |
Saleh MA, Ishii K, Kim Y, Murakami A, Amagai M, Shibaguchi H, Tsuru H, Kuroki M, Murata A, Okuyama K, Sawada A, Egawa Y, Sakano S, Yagita H, Zúñiga-Pflücker JC, et al. Cell adhesion in immunity (WS-103) Chairpersons: Tatsuo Kinashi, Sirpa Jalkanen International Immunology. 22. DOI: 10.1093/Intimm/Dxq365 |
0.373 |
|
| 2009 |
Holmes R, Zúñiga-Pflücker JC. The OP9-DL1 system: generation of T-lymphocytes from embryonic or hematopoietic stem cells in vitro. Csh Protocols. 2009. PMID 20147086 DOI: 10.1101/Pdb.Prot5156 |
0.633 |
|
| 2009 |
Lauritsen JP, Wong GW, Lee SY, Lefebvre JM, Ciofani M, Rhodes M, Kappes DJ, Zúñiga-Pflücker JC, Wiest DL. Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. Immunity. 31: 565-75. PMID 19833086 DOI: 10.1016/J.Immuni.2009.07.010 |
0.605 |
|
| 2009 |
Zúñiga-Pflücker JC. The Original Intrathymic Progenitor from Which T Cells Originate Journal of Immunology. 183: 3-4. PMID 19542424 DOI: 10.4049/Jimmunol.0990043 |
0.65 |
|
| 2009 |
Awong G, Herer E, Surh CD, Dick JE, La Motte-Mohs RN, Zúñiga-Pflücker JC. Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells. Blood. 114: 972-82. PMID 19491395 DOI: 10.1182/Blood-2008-10-187013 |
0.842 |
|
| 2008 |
Martin CH, Woll PS, Ni Z, Zúñiga-Pflücker JC, Kaufman DS. Differences in lymphocyte developmental potential between human embryonic stem cell and umbilical cord blood-derived hematopoietic progenitor cells. Blood. 112: 2730-7. PMID 18621931 DOI: 10.1182/Blood-2008-01-133801 |
0.701 |
|
| 2008 |
Baron ML, Gauchat D, La Motte-Mohs R, Kettaf N, Abdallah A, Michiels T, Zúñiga-Pflücker JC, Sékaly RP. TLR Ligand-Induced Type I IFNs Affect Thymopoiesis. Journal of Immunology (Baltimore, Md. : 1950). 180: 7134-46. PMID 18490712 DOI: 10.4049/Jimmunol.180.11.7134 |
0.315 |
|
| 2008 |
Zakrzewski JL, Suh D, Markley JC, Smith OM, King C, Goldberg GL, Jenq R, Holland AM, Grubin J, Cabrera-Perez J, Brentjens RJ, Lu SX, Rizzuto G, Sant'Angelo DB, Riviere I, et al. Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors. Nature Biotechnology. 26: 453-61. PMID 18376399 DOI: 10.1038/Nbt1395 |
0.583 |
|
| 2008 |
Awong G, La Motte-Mohs RN, Zúñiga-Pflücker JC. In vitro human T cell development directed by notch-ligand interactions. Methods in Molecular Biology (Clifton, N.J.). 430: 135-42. PMID 18370296 DOI: 10.1007/978-1-59745-182-6_9 |
0.835 |
|
| 2008 |
Zakrzewski JL, Suh D, Markley JC, Smith OM, King C, Goldberg G, Jenq R, Holland AM, Grubin J, Cabrera-Perez J, Lu SX, Rizzuto G, Sant'Angelo DB, Riviere I, Sadelain M, ... Zuniga-Pflucker JC, et al. 344: Off-the-Shelf Tumor Immunotherapy with Genetically Enhanced Allogeneic T-Cell Precursors Biology of Blood and Marrow Transplantation. 14: 126. DOI: 10.1016/J.Bbmt.2007.12.354 |
0.478 |
|
| 2007 |
Awong G, La Motte-Mohs RN, Zúñiga-Pflücker JC. Generation of pro-T cells in vitro: potential for immune reconstitution. Seminars in Immunology. 19: 341-9. PMID 17997108 DOI: 10.1016/J.Smim.2007.10.005 |
0.855 |
|
| 2007 |
Michie AM, Chan AC, Ciofani M, Carleton M, Lefebvre JM, He Y, Allman DM, Wiest DL, Zúñiga-Pflücker JC, Izon DJ. Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals. International Immunology. 19: 1421-30. PMID 17981791 DOI: 10.1093/Intimm/Dxm113 |
0.584 |
|
| 2007 |
Zúñiga-Pflücker JC. CD8+ T cells are kept in tune by modulating IL-7 responsiveness. Nature Immunology. 8: 1027-1028. PMID 17878908 DOI: 10.1038/Ni1007-1027 |
0.638 |
|
| 2007 |
Koltsova EK, Ciofani M, Benezra R, Miyazaki T, Clipstone N, Zúñiga-Pflücker JC, Wiest DL. Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint. Journal of Immunology (Baltimore, Md. : 1950). 179: 4694-703. PMID 17878368 DOI: 10.4049/Jimmunol.179.7.4694 |
0.382 |
|
| 2007 |
Pooter RFd, Zúñiga-Pflücker JC. Generation of immunocompetent T cells from embryonic stem cells. Methods of Molecular Biology. 380: 73-81. PMID 17876088 DOI: 10.1007/978-1-59745-395-0_5 |
0.657 |
|
| 2007 |
Bhandoola A, von Boehmer H, Petrie HT, Zúñiga-Pflücker JC. Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from. Immunity. 26: 678-89. PMID 17582341 DOI: 10.1016/J.Immuni.2007.05.009 |
0.659 |
|
| 2007 |
Ciofani M, Zúñiga-Pflücker JC. The thymus as an inductive site for T lymphopoiesis. Annual Review of Cell and Developmental Biology. 23: 463-493. PMID 17506693 DOI: 10.1146/Annurev.Cellbio.23.090506.123547 |
0.662 |
|
| 2007 |
Pooter Rd, Zúñiga-Pflücker JC. T-cell potential and development in vitro: the OP9-DL1 approach. Current Opinion in Immunology. 19: 163-168. PMID 17303399 DOI: 10.1016/J.Coi.2007.02.011 |
0.63 |
|
| 2007 |
Petrie HT, Zúñiga-Pflücker JC. Zoned Out: Functional Mapping of Stromal Signaling Microenvironments in the Thymus Annual Review of Immunology. 25: 649-679. PMID 17291187 DOI: 10.1146/Annurev.Immunol.23.021704.115715 |
0.634 |
|
| 2007 |
Pipkin ME, Ljutic B, Cruz-Guilloty F, Nouzova M, Rao A, Zúñiga-Pflücker JC, Lichtenheld MG. Chromosome transfer activates and delineates a locus control region for perforin. Immunity. 26: 29-41. PMID 17222571 DOI: 10.1016/J.Immuni.2006.11.009 |
0.318 |
|
| 2007 |
Motte-Mohs RNL, Awong G, Zuniga-Pflucker JC. In Vitro Models of Human T Cell Development: Dishing Out Progenitor T Cells Current Immunology Reviews. 3: 57-75. DOI: 10.2174/157339507779802205 |
0.861 |
|
| 2007 |
Zakrzewski JL, Suh D, Smith OM, King C, Goldberg GL, Jenq R, Holland AM, Grubin J, Lu SX, Cabrera-Perez J, Rizzuto G, Sant’Angelo DB, van den Brink MR, Markley JC, Riviere I, ... ... Zuniga-Pflucker JC, et al. Targeted ‘Off-the-Shelf’ Tumor Immunotherapy Using Allogeneic T-Cell Precursors. Blood. 110: 579-579. DOI: 10.1182/Blood.V110.11.579.579 |
0.641 |
|
| 2007 |
Zúñiga-Pflücker JC, Brink MRMvd. EditorialGiving T cells a chance to come back Seminars in Immunology. 19: 279. DOI: 10.1016/J.Smim.2007.11.001 |
0.613 |
|
| 2006 |
Ramsdell F, Zúñiga-Pflücker JC, Takahama Y. In Vitro Systems for the Study of T Cell Development: Fetal Thymus Organ Culture and OP9‐DL1 Cell Coculture Current Protocols in Immunology. 71. PMID 18432973 DOI: 10.1002/0471142735.Im0318S71 |
0.633 |
|
| 2006 |
Aublin A, Ciofani M, Willkomm N, Hamrouni A, Szymczak-Workman AL, Takahashi T, Sandjeu Y, Guillaume P, Vignali DA, Michielin O, Zúñiga-Pflücker JC, Maryanski JL. A natural structural variant of the mouse TCR beta-chain displays intrinsic receptor function and antigen specificity. Journal of Immunology (Baltimore, Md. : 1950). 177: 8587-94. PMID 17142757 DOI: 10.4049/Jimmunol.177.12.8587 |
0.514 |
|
| 2006 |
de Pooter RF, Schmitt TM, Zúñiga-Pflücker JC. In vitro generation of T lymphocytes from embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 330: 113-21. PMID 16846020 DOI: 10.1385/1-59745-036-7:113 |
0.566 |
|
| 2006 |
Ciofani M, Knowles GC, Wiest DL, Boehmer Hv, Zúñiga-Pflücker JC. Stage-Specific and Differential Notch Dependency at the αβ and γδ T Lineage Bifurcation Immunity. 25: 105-116. PMID 16814577 DOI: 10.1016/J.Immuni.2006.05.010 |
0.685 |
|
| 2006 |
Wang D, Claus CL, Vaccarelli G, Braunstein M, Schmitt TM, Zúñiga-Pflücker JC, Rothenberg EV, Anderson MK. The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors. Journal of Immunology (Baltimore, Md. : 1950). 177: 109-19. PMID 16785505 DOI: 10.4049/Jimmunol.177.1.109 |
0.587 |
|
| 2006 |
Zúñiga-Pflücker JC, Ciofani M. Pre-T Cell Receptor's clashing Signals: “Should I Stay or Should I Go” Immunity. 24: 669-670. PMID 16782022 DOI: 10.1016/J.Immuni.2006.06.006 |
0.476 |
|
| 2006 |
Ciofani M, Zúñiga-Pflücker JC. A survival guide to early T cell development. Immunologic Research. 34: 117-132. PMID 16760572 DOI: 10.1385/Ir:34:2:117 |
0.522 |
|
| 2006 |
Garbe AI, Krueger A, Gounari F, Zúñiga-Pflücker JC, Boehmer Hv. Differential synergy of Notch and T cell receptor signaling determines αβ versus γδ lineage fate Journal of Experimental Medicine. 203: 1579-1590. PMID 16754723 DOI: 10.1084/Jem.20060474 |
0.574 |
|
| 2006 |
Pooter RFd, Schmitt TM, Pompa JLdl, Fujiwara Y, Orkin SH, Zúñiga-Pflücker JC. Notch Signaling Requires GATA-2 to Inhibit Myelopoiesis from Embryonic Stem Cells and Primary Hemopoietic Progenitors Journal of Immunology. 176: 5267-5275. PMID 16621992 DOI: 10.4049/Jimmunol.176.9.5267 |
0.56 |
|
| 2006 |
Yokota T, Huang J, Tavian M, Nagai Y, Hirose J, Zúñiga-Pflücker JC, Péault B, Kincade PW. Tracing the first waves of lymphopoiesis in mice. Development (Cambridge, England). 133: 2041-51. PMID 16611687 DOI: 10.1242/Dev.02349 |
0.614 |
|
| 2006 |
Yoshida T, Ng SY, Zuniga-Pflucker JC, Georgopoulos K. Early hematopoietic lineage restrictions directed by Ikaros. Nature Immunology. 7: 382-91. PMID 16518393 DOI: 10.1038/Ni1314 |
0.399 |
|
| 2006 |
Schmitt TM, Zúñiga-Pflücker JC. T‐cell development, doing it in a dish Immunological Reviews. 209: 95-102. PMID 16448536 DOI: 10.1111/J.0105-2896.2006.00353.X |
0.639 |
|
| 2006 |
Mohtashami M, Zúñiga-Pflücker JC. Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development. Journal of Immunology (Baltimore, Md. : 1950). 176: 730-4. PMID 16393955 DOI: 10.4049/Jimmunol.176.2.730 |
0.588 |
|
| 2005 |
Huang J, Garrett KP, Pelayo R, Zúñiga-Pflücker JC, Petrie HT, Kincade PW. Propensity of adult lymphoid progenitors to progress to DN2/3 stage thymocytes with Notch receptor ligation. Journal of Immunology (Baltimore, Md. : 1950). 175: 4858-65. PMID 16210587 DOI: 10.4049/Jimmunol.175.8.4858 |
0.524 |
|
| 2005 |
Konrad MAP, Zúñiga-Pflücker JC. The BTG/TOB family protein TIS21 regulates stage-specific proliferation of developing thymocytes. European Journal of Immunology. 35: 3030-3042. PMID 16163674 DOI: 10.1002/Eji.200526345 |
0.611 |
|
| 2005 |
Ciofani M, Zúñiga-Pflücker JC. Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism. Nature Immunology. 6: 881-888. PMID 16056227 DOI: 10.1038/Ni1234 |
0.564 |
|
| 2005 |
Zúñiga-Pflücker JC, Schmitt TM. Unraveling the origin of lymphocyte progenitors European Journal of Immunology. 35: 2016-2018. PMID 15971277 DOI: 10.1002/Eji.200535106 |
0.56 |
|
| 2005 |
Schmitt TM, Zuniga-Pflucker JC. Thymus-derived signals regulate early T-cell development. Critical Reviews in Immunology. 25: 141-159. PMID 15952934 DOI: 10.1615/Critrevimmunol.V25.I2.40 |
0.62 |
|
| 2005 |
Taghon TN, David ES, Zúñiga-Pflücker JC, Rothenberg EV. Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling. Genes & Development. 19: 965-78. PMID 15833919 DOI: 10.1101/Gad.1298305 |
0.571 |
|
| 2005 |
Ljutic B, Carlyle JR, Filipp D, Nakagawa R, Julius M, Zúñiga-Pflücker JC. Functional requirements for signaling through the stimulatory and inhibitory mouse NKR-P1 (CD161) NK cell receptors. Journal of Immunology (Baltimore, Md. : 1950). 174: 4789-96. PMID 15814704 DOI: 10.4049/Jimmunol.174.8.4789 |
0.438 |
|
| 2005 |
Balciunaite G, Ceredig R, Fehling HJ, Zúñiga-Pflücker JC, Rolink AG. The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation. European Journal of Immunology. 35: 1292-300. PMID 15770699 DOI: 10.1002/Eji.200425822 |
0.544 |
|
| 2005 |
Terra R, Louis I, Le Blanc R, Ouellet S, Zúñiga-Pflücker JC, Perreault C. T-cell generation by lymph node resident progenitor cells. Blood. 106: 193-200. PMID 15746078 DOI: 10.1182/Blood-2004-12-4886 |
0.534 |
|
| 2005 |
Mandal M, Borowski C, Palomero T, Ferrando AA, Oberdoerffer P, Meng F, Ruiz-Vela A, Ciofani M, Zuniga-Pflucker JC, Screpanti I, Look AT, Korsmeyer SJ, Rajewsky K, Von Boehmer H, Aifantis I. The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival Journal of Experimental Medicine. 201: 603-614. PMID 15728238 DOI: 10.1084/Jem.20041924 |
0.563 |
|
| 2005 |
Motte-Mohs RNL, Herer E, Zúñiga-Pflücker JC. Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro Blood. 105: 1431-1439. PMID 15494433 DOI: 10.1182/Blood-2004-04-1293 |
0.723 |
|
| 2005 |
de Pooter RF, Cho SK, Zúñiga-Pflücker JC. In vitro generation of lymphocytes from embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 290: 135-47. PMID 15361660 DOI: 10.1385/1-59259-838-2:135 |
0.834 |
|
| 2005 |
Zakrzewski JL, Kochman AA, Lu SX, Terwey TH, Kim TD, Hubbard VM, Muriglan SJ, Suh D, Cabrera-Perez J, Radhakrishnan R, Heller G, Zuniga-Pflucker JC, Alpdogan O, Brink MRMvd. Adoptive Transfer of In Vitro Generated T Cell Precursors Enhances Donor T Cell Reconstitution and Graft-Versus-Tumor Activity in Allogeneic Hematopoietic Stem Cell Transplantation Recipients. Blood. 106: 63-63. DOI: 10.1182/Blood.V106.11.63.63 |
0.674 |
|
| 2005 |
Zakrzewski JL, Kochman A, Muriglan SJ, Lu S, Kim TD, Zuniga-Pflucker JC, Alpdogan O, Brink MRMvd. Adoptive transfer of in vitro-generated T cell precursors enhances posttransplant donor T cell reconstitution in recipients of an allogeneic hematopoietic stem cell transplantation Biology of Blood and Marrow Transplantation. 11: 4-5. DOI: 10.1016/J.Bbmt.2004.12.013 |
0.583 |
|
| 2004 |
Schmitt TM, Ciofani M, Petrie HT, Zúñiga-Pflücker JC. Maintenance of T Cell Specification and Differentiation Requires Recurrent Notch Receptor–Ligand Interactions Journal of Experimental Medicine. 200: 469-479. PMID 15314075 DOI: 10.1084/Jem.20040394 |
0.701 |
|
| 2004 |
Porritt HE, Rumfelt LL, Tabrizifard S, Schmitt TM, Zúñiga-Pflücker JC, Petrie HT. Heterogeneity among DN1 Prothymocytes Reveals Multiple Progenitors with Different Capacities to Generate T Cell and Non-T Cell Lineages Immunity. 20: 735-745. PMID 15189738 DOI: 10.1016/J.Immuni.2004.05.004 |
0.667 |
|
| 2004 |
Ciofani M, Schmitt TM, Ciofani A, Michie AM, Çuburu N, Aublin A, Maryanski JL, Zúñiga-Pflücker JC. Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation Journal of Immunology. 172: 5230-5239. PMID 15100261 DOI: 10.4049/Jimmunol.172.9.5230 |
0.48 |
|
| 2004 |
Schmitt TM, de Pooter RF, Gronski MA, Cho SK, Ohashi PS, Zúñiga-Pflücker JC. Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nature Immunology. 5: 410-7. PMID 15034575 DOI: 10.1038/Ni1055 |
0.861 |
|
| 2004 |
Okada H, Bakal C, Shahinian A, Elia A, Wakeham A, Suh WK, Duncan GS, Ciofani M, Rottapel R, Zúñiga-Pflücker JC, Mak TW. Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. The Journal of Experimental Medicine. 199: 399-410. PMID 14757745 DOI: 10.1084/Jem.20032092 |
0.568 |
|
| 2004 |
Zúñiga-Pflücker JC. T-cell development made simple Nature Reviews Immunology. 4: 67-72. PMID 14704769 DOI: 10.1038/Nri1257 |
0.628 |
|
| 2003 |
Cho SK, Zúñiga-Pflücker JC. Development of lymphoid lineages from embryonic stem cells in vitro. Methods in Enzymology. 365: 158-69. PMID 14696344 DOI: 10.1016/S0076-6879(03)65011-1 |
0.819 |
|
| 2003 |
Ljutic B, Carlyle JR, Zúñiga-Pflücker JC. Identification of upstream cis-acting regulatory elements controlling lineage-specific expression of the mouse NK cell activation receptor, NKR-P1C. The Journal of Biological Chemistry. 278: 31909-17. PMID 12813047 DOI: 10.1074/Jbc.M212869200 |
0.45 |
|
| 2003 |
de Pooter RF, Cho SK, Carlyle JR, Zúñiga-Pflücker JC. In vitro generation of T lymphocytes from embryonic stem cell-derived prehematopoietic progenitors. Blood. 102: 1649-53. PMID 12738664 DOI: 10.1182/Blood-2003-01-0224 |
0.854 |
|
| 2003 |
Haks MC, Belkowski SM, Ciofani M, Rhodes M, Lefebvre JM, Trop S, Hugo P, Zúñiga-Pflücker JC, Wiest DL. Low Activation Threshold As a Mechanism for Ligand-Independent Signaling in Pre-T Cells Journal of Immunology. 170: 2853-2861. PMID 12626535 DOI: 10.4049/Jimmunol.170.6.2853 |
0.429 |
|
| 2003 |
Kim S, Motte-Mohs RNAL, Rudolph D, Zúñiga-Pflücker JC, Mak TW. The role of nuclear factor-κB essential modulator (NEMO) in B cell development and survival Proceedings of the National Academy of Sciences of the United States of America. 100: 1203-1208. PMID 12538858 DOI: 10.1073/Pnas.0337707100 |
0.395 |
|
| 2002 |
Schmitt TM, Zúñiga-Pflücker JC. Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro Immunity. 17: 749-756. PMID 12479821 DOI: 10.1016/S1074-7613(02)00474-0 |
0.739 |
|
| 2002 |
Michie AM, Zúñiga-Pflücker JC. Regulation of thymocyte differentiation: pre-TCR signals and β-selection Seminars in Immunology. 14: 311-323. PMID 12220932 DOI: 10.1016/S1044-5323(02)00064-7 |
0.496 |
|
| 2001 |
Mariathasan S, Zakarian A, Bouchard D, Michie AM, Zúñiga-Pflücker JC, Ohashi PS. Duration and strength of extracellular signal-regulated kinase signals are altered during positive versus negative thymocyte selection. Journal of Immunology (Baltimore, Md. : 1950). 167: 4966-73. PMID 11673503 DOI: 10.4049/Jimmunol.167.9.4966 |
0.32 |
|
| 2001 |
Sasaki T, Wada T, Kishimoto H, Irie-Sasaki J, Matsumoto G, Goto T, Yao Z, Wakeham A, Mak TW, Suzuki A, Cho SK, Zuniga-Pflucker JC, Oliveira-dos-Santos AJ, Katada T, Nishina H, et al. The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells. The Journal of Experimental Medicine. 194: 757-68. PMID 11560992 DOI: 10.1084/Jem.194.6.757 |
0.768 |
|
| 2001 |
Michie AM, Soh JW, Hawley RG, Weinstein IB, Zuniga-Pflucker JC. Allelic exclusion and differentiation by protein kinase C-mediated signals in immature thymocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 609-14. PMID 11149941 DOI: 10.1073/Pnas.98.2.609 |
0.491 |
|
| 2000 |
Michie AM, Zúñiga-Pflücker JC. In vivo detection of intracellular signaling pathways in developing thymocytes. Developmental Immunology. 8: 31-45. PMID 11293810 DOI: 10.1155/2000/97820 |
0.422 |
|
| 2000 |
Kruisbeek AM, Haks MC, Carleton M, Wiest DL, Michie AM, Zúñiga-Pflücker JC. Branching out to gain control: how the pre-TCR is linked to multiple functions Immunology Today. 21: 637-644. PMID 11114425 DOI: 10.1016/S0167-5699(00)01744-8 |
0.465 |
|
| 2000 |
Trop S, Rhodes M, Wiest DL, Hugo P, Zúñiga-Pflücker JC. Competitive Displacement of pTα by TCR-α During TCR Assembly Prevents Surface Coexpression of Pre-TCR and αβ TCR Journal of Immunology. 165: 5566-5572. PMID 11067911 DOI: 10.4049/Jimmunol.165.10.5566 |
0.511 |
|
| 2000 |
Michie AM, Zúñiga-Pflücker JC. Transfection and transcription of genes in developing thymocytes. Methods of Molecular Biology. 134: 55-62. PMID 10730248 DOI: 10.1385/1-59259-682-7:55 |
0.521 |
|
| 2000 |
Michie AM, Carlyle JR, Schmitt TM, Ljutic B, Cho SK, Fong Q, Zúñiga-Pflücker JC. Clonal characterization of a bipotent T cell and NK cell progenitor in the mouse fetal thymus. Journal of Immunology (Baltimore, Md. : 1950). 164: 1730-3. PMID 10657617 DOI: 10.4049/Jimmunol.164.4.1730 |
0.857 |
|
| 1999 |
Michie AM, Trop S, Wiest DL, Zúñiga-Pflücker JC. Extracellular signal-regulated kinase (ERK) activation by the pre-T cell receptor in developing thymocytes in vivo. Journal of Experimental Medicine. 190: 1647-1656. PMID 10587355 DOI: 10.1084/Jem.190.11.1647 |
0.561 |
|
| 1999 |
Cho SK, Webber TD, Carlyle JR, Nakano T, Lewis SM, Zúñiga-Pflücker JC. Functional characterization of B lymphocytes generated in vitro from embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 9797-802. PMID 10449774 DOI: 10.1073/Pnas.96.17.9797 |
0.794 |
|
| 1998 |
Carlyle JR, Zúñiga-Pflücker JC. Requirement for the thymus in alphabeta T lymphocyte lineage commitment. Immunity. 9: 187-97. PMID 9729039 DOI: 10.1016/S1074-7613(00)80601-9 |
0.604 |
|
| 1997 |
Carlyle JR, Michie AM, Furlonger C, Nakano T, Lenardo MJ, Paige CJ, Zúñiga-Pflücker JC. Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes. The Journal of Experimental Medicine. 186: 173-82. PMID 9221746 DOI: 10.1084/Jem.186.2.173 |
0.62 |
|
| 1996 |
Zúñiga-Pflücker JC, Lenardo MJ. Regulation of thymocyte development from immature progenitors Current Opinion in Immunology. 8: 215-224. PMID 8725945 DOI: 10.1016/S0952-7915(96)80060-4 |
0.612 |
|
| 1996 |
Jiang D, Lenardo MJ, Zuniga-Pflucker JC. p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement. Journal of Experimental Medicine. 183: 1923-1928. PMID 8666950 DOI: 10.1084/Jem.183.4.1923 |
0.52 |
|
| 1996 |
Fisher GH, Lenardo MJ, Zúñiga-Pflücker JC. Synergy between T Cell Receptor and Fas (CD95/APO-1) Signaling in Mouse Thymocyte Death Cellular Immunology. 169: 99-106. PMID 8612301 DOI: 10.1006/Cimm.1996.0096 |
0.45 |
|
| 1995 |
Zheng L, Boehme SA, Critchfield JM, Zuniga-Pflucker JC, Freedman M, Lenardo MJ. Immunological tolerance by antigen-induced apoptosis of mature T lymphocytes. Advances in Experimental Medicine and Biology. 365: 81-9. PMID 7887316 DOI: 10.1007/978-1-4899-0987-9_9 |
0.512 |
|
| 1995 |
Albright JW, Zúñiga-Pflücker JC, Albright JF. Transcriptional Control of IL-2 and IL-4 in T Cells of Young and Old Mice Cellular Immunology. 164: 170-175. PMID 7656324 DOI: 10.1006/Cimm.1995.1158 |
0.517 |
|
| 1995 |
Zuniga-Pflucker JC, Jiang D, Lenardo MJ. Requirement for TNF-alpha and IL-1 alpha in fetal thymocyte commitment and differentiation Science. 268: 1906-1909. PMID 7541554 DOI: 10.1126/Science.7541554 |
0.46 |
|
| 1995 |
Critchfield JM, Zúñiga-Pflücker JC, Lenardo MJ. Parameters controlling the programmed death of mature mouse T lymphocytes in high-dose suppression Cellular Immunology. 160: 71-78. PMID 7531119 DOI: 10.1016/0008-8749(95)80011-7 |
0.545 |
|
| 1994 |
Zúñiga-Pflücker JC, Jiang D, Schwartzberg PL, Lenardo MJ. Sublethal γ-radiation induces differentiation of CD4-/CD8- into CD4+/CD8+ thymocytes without T cell receptor β rearrangement in recombinase activation gene 2-/- mice Journal of Experimental Medicine. 180: 1517-1521. PMID 7931082 DOI: 10.1084/Jem.180.4.1517 |
0.526 |
|
| 1993 |
Zúñiga-Pflücker JC, Schwartz HL, Lenardo MJ. Gene transcription in differentiating immature T cell receptor(neg) thymocytes resembles antigen-activated mature T cells. Journal of Experimental Medicine. 178: 1139-1149. PMID 8376926 DOI: 10.1084/Jem.178.4.1139 |
0.564 |
|
| 1990 |
Zúñiga-Pflücker JC, Jones LA, Longo DL, Kruisbeek AM. CD8 is required during positive selection of CD4-/CD8+ T cells. Journal of Experimental Medicine. 171: 427-437. PMID 1968084 DOI: 10.1084/Jem.171.2.427 |
0.566 |
|
| 1989 |
Zuñiga-Pflücker JC, McCarthy SA, Weston M, Longo DL, Singer A, Kruisbeek AM. Role of CD4 in thymocyte selection and maturation. The Journal of Experimental Medicine. 169: 2085-96. PMID 2525172 DOI: 10.1084/Jem.169.6.2085 |
0.491 |
|
| 1989 |
Zuñiga-Pflucker JC, Longo DL, Kruisbeek AM. Positive selection of CD4-CD8+ T cells in the thymus of normal mice. Nature. 338: 76-8. PMID 2521924 DOI: 10.1038/338076A0 |
0.607 |
|
| 1989 |
Zuniga-Pflücker JC, Jones LA, Longo DL, Kruisbeek AM. Both TCR/MHC and Accessory Molecule/MHC Interactions Are Required for Positive and Negative Selection of Mature T Cells in the Thymus Cold Spring Harbor Symposia On Quantitative Biology. 54: 153-158. PMID 2517918 DOI: 10.1101/Sqb.1989.054.01.019 |
0.483 |
|
| 1989 |
Veillette A, Zúñiga-Pflücker JC, Bolen JB, Kruisbeek AM. Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways Journal of Experimental Medicine. 170: 1671-1680. PMID 2478653 DOI: 10.1084/Jem.170.5.1671 |
0.499 |
|
| 1988 |
Tentori L, Longo DL, Zuñiga-Pflucker JC, Wing C, Kruisbeek AM. Essential role of the interleukin 2-interleukin 2 receptor pathway in thymocyte maturation in vivo. Journal of Experimental Medicine. 168: 1741-1747. PMID 3263466 DOI: 10.1084/Jem.168.5.1741 |
0.465 |
|
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