Richard Kremer - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Molecular Biology, Oncology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Burt LA, Billington EO, Rose MS, Kremer R, Hanley DA, Boyd SK. Reply to Vitamin D Supplements: Is Bone Loss by HR-pQCT Really Negative? Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 33534173 DOI: 10.1002/jbmr.4247  0.328
2020 Burt LA, Billington EO, Rose MS, Kremer R, Hanley DA, Boyd SK. Reply to Effects of High-Dose Vitamin D Supplementation on Bone Fragility. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 33095473 DOI: 10.1002/jbmr.4190  0.314
2020 Burt LA, Billington EO, Rose MS, Kremer R, Hanley DA, Boyd SK. Adverse effects of high-dose vitamin D supplementation on volumetric bone density are greater in females than males. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32777104 DOI: 10.1002/Jbmr.4152  0.417
2019 Sheng L, Turner AG, Barratt K, Kremer R, Morris HA, Callen DF, Anderson PH, Tarulli GA. Mammary-specific Ablation of Cyp24a1 Inhibits Development, Reduces Proliferation and Increases Sensitivity to Vitamin D. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30654105 DOI: 10.1016/j.jsbmb.2019.01.005  0.354
2018 Li J, Doré-Savard L, Sellin K, Camirand A, Kremer R. Abstract 3062: Ablation of parathyroid hormone-related protein in the triple negative human breast cancer line MDA-MB-231 inhibits its cancer stem cell phenotype Cancer Research. 78: 3062-3062. DOI: 10.1158/1538-7445.Am2018-3062  0.319
2017 Jusu S, Presley JF, Williams C, Das SK, Jean-Claude B, Kremer R. Examination of VDR/RXR/DRIP205 Interaction, Intranuclear Localization and DNA Binding in Ras-transformed Keratinocytes and Its Implication for Designing Optimal Vitamin D Therapy in Cancer. Endocrinology. PMID 29300860 DOI: 10.1210/En.2017-03098  0.349
2017 Haimi M, Kremer R. Vitamin D deficiency/insufficiency from childhood to adulthood: Insights from a sunny country. World Journal of Clinical Pediatrics. 6: 1-9. PMID 28224090 DOI: 10.5409/wjcp.v6.i1.1  0.308
2016 Jusu S, Presley JF, Kremer R. Phosphorylation of Human Retinoid X Receptor α at Serine 260 Impairs its Subcellular Localization, Receptor Interaction, Nuclear Mobility and 1α, 25dihydroxyvitamin D3 - Dependent DNA Binding in Ras -Transformed Keratinocytes. The Journal of Biological Chemistry. PMID 27852823 DOI: 10.1074/Jbc.M116.758185  0.475
2016 Li J, Luco AL, Ochietti B, Fadhil I, Camirand A, Reinhardt TA, St-Arnaud R, Muller W, Kremer R. Tumoral Vitamin D Synthesis by CYP27B1 1-α-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-κB Modulation. Endocrinology. en20151824. PMID 27119753 DOI: 10.1210/En.2015-1824  0.449
2015 Rossdeutscher L, Li J, Luco AL, Fadhil I, Ochietti B, Camirand A, Huang DC, Reinhardt TA, Muller W, Kremer R. Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer. Cancer Prevention Research (Philadelphia, Pa.). 8: 120-8. PMID 25468832 DOI: 10.1158/1940-6207.CAPR-14-0110  0.372
2014 Tabatabaei N, Rodd CJ, Kremer R, Weiler HA. High vitamin D status before conception, but not during pregnancy, is inversely associated with maternal gestational diabetes mellitus in guinea pigs. The Journal of Nutrition. 144: 1994-2001. PMID 25342700 DOI: 10.3945/Jn.114.197814  0.354
2014 Tabatabaei N, Rodd CJ, Kremer R, Khavandgar Z, Murshed M, Weiler HA. Dietary vitamin D during pregnancy has dose-dependent effects on long bone density and architecture in guinea pig offspring but not the sows. The Journal of Nutrition. 144: 1985-93. PMID 25320192 DOI: 10.3945/Jn.114.197806  0.393
2014 Tabatabaei N, Giguère Y, Forest JC, Rodd CJ, Kremer R, Weiler HA. Osteocalcin is higher across pregnancy in Caucasian women with gestational diabetes mellitus. Canadian Journal of Diabetes. 38: 307-13. PMID 24986803 DOI: 10.1016/J.Jcjd.2014.02.007  0.307
2013 Fang H, Kremer R, Sebag M. A Transgenic Model Of Multiple Myeloma Bone Disease Shows Profound Mesenchymal Stem Cell Impairment Blood. 122: 130-130. DOI: 10.1182/Blood.V122.21.130.130  0.302
2013 Li J, Karaplis AC, Huang DC, Siegel PM, Camirand A, Yang XF, Muller WJ, Kremer R. Abstract 89: Parathyroid Hormone-related Protein (PTHrP) is critical for breast tumour metastasis and may constitute a novel target for therapeutic intervention. Cancer Research. 73: 89-89. DOI: 10.1158/1538-7445.Am2013-89  0.313
2012 Vidal C, Bermeo S, Li W, Huang D, Kremer R, Duque G. Interferon gamma inhibits adipogenesis in vitro and prevents marrow fat infiltration in oophorectomized mice. Stem Cells (Dayton, Ohio). 30: 1042-8. PMID 22331815 DOI: 10.1002/Stem.1063  0.309
2011 Li J, Karaplis AC, Huang DC, Siegel PM, Camirand A, Yang XF, Muller WJ, Kremer R. PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target. The Journal of Clinical Investigation. 121: 4655-69. PMID 22056386 DOI: 10.1172/Jci46134  0.323
2010 Lamblin M, Dabbas B, Spingarn R, Mendoza-Sanchez R, Wang TT, An BS, Huang DC, Kremer R, White JH, Gleason JL. Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids. Bioorganic & Medicinal Chemistry. 18: 4119-37. PMID 20452225 DOI: 10.1016/J.Bmc.2010.03.078  0.468
2010 Gilsanz V, Kremer A, Mo AO, Wren TA, Kremer R. Vitamin D status and its relation to muscle mass and muscle fat in young women. The Journal of Clinical Endocrinology and Metabolism. 95: 1595-601. PMID 20164290 DOI: 10.1097/Ogx.0B013E3182021Fd9  0.329
2009 Duque G, Huang DC, Macoritto M, Rivas D, Yang XF, Ste-Marie LG, Kremer R. Autocrine regulation of interferon gamma in mesenchymal stem cells plays a role in early osteoblastogenesis. Stem Cells (Dayton, Ohio). 27: 550-8. PMID 19096039 DOI: 10.1634/Stemcells.2008-0886  0.335
2009 Kremer R, Campbell PP, Reinhardt T, Gilsanz V. Vitamin D status and its relationship to body fat, final height, and peak bone mass in young women. The Journal of Clinical Endocrinology and Metabolism. 94: 67-73. PMID 18984659 DOI: 10.1210/Jc.2008-1575  0.356
2008 Macoritto M, Nguyen-Yamamoto L, Huang DC, Samuel S, Yang XF, Wang TT, White JH, Kremer R. Phosphorylation of the human retinoid X receptor alpha at serine 260 impairs coactivator(s) recruitment and induces hormone resistance to multiple ligands. The Journal of Biological Chemistry. 283: 4943-56. PMID 18003614 DOI: 10.1074/Jbc.M707517200  0.408
2006 Vecino-Vecino C, Gratton M, Kremer R, Rodriguez-Mañas L, Duque G. Seasonal variance in serum levels of vitamin D determines a compensatory response by parathyroid hormone: Study in an ambulatory elderly population in Quebec Gerontology. 52: 33-39. PMID 16439822 DOI: 10.1159/000089823  0.404
2006 Sebag M, Stewart K, Palmer S, Kremer R, Bergsagel PL, Chesi M. A Novel Transgenic Mouse Model of Multiple Myeloma Reliably Predicts Drug Response. Blood. 108: 241-241. DOI: 10.1182/Blood.V108.11.241.241  0.301
2005 Duque G, Macoritto M, Dion N, Ste-Marie LG, Kremer R. 1,25(OH)2D3 acts as a bone-forming agent in the hormone-independent senescence-accelerated mouse (SAM-P/6). American Journal of Physiology. Endocrinology and Metabolism. 288: E723-30. PMID 15572658 DOI: 10.1152/Ajpendo.00180.2004  0.463
2005 Gao X, Butler IS, Kremer R. A near-infrared Fourier transform Raman spectroscopy of epidermal keratinocytes: changes in the protein-DNA structure following malignant transformation. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 61: 27-35. PMID 15556417 DOI: 10.1016/J.Saa.2004.03.007  0.313
2004 Duque G, Macoritto M, Kremer R. Vitamin D treatment of senescence accelerated mice (SAM-P/6) induces several regulators of stromal cell plasticity. Biogerontology. 5: 421-9. PMID 15609106 DOI: 10.1007/S10522-004-3192-5  0.443
2004 Duque G, El Abdaimi K, Henderson JE, Lomri A, Kremer R. Vitamin D inhibits Fas ligand-induced apoptosis in human osteoblasts by regulating components of both the mitochondrial and Fas-related pathways Bone. 35: 57-64. PMID 15207741 DOI: 10.1016/J.Bone.2004.03.005  0.428
2004 Duque G, Macoritto M, Kremer R. 1,25(OH)2D3 inhibits bone marrow adipogenesis in senescence accelerated mice (SAM-P/6) by decreasing the expression of peroxisome proliferator-activated receptor gamma 2 (PPARgamma2). Experimental Gerontology. 39: 333-8. PMID 15036392 DOI: 10.1016/J.Exger.2003.11.008  0.432
2003 El-Abdaimi K, Ste-Marie LG, Papavasiliou V, Dion N, Cardinal PE, Huang D, Kremer R. Pamidronate prevents the development of skeletal metastasis in nude mice transplanted with human breast cancer cells by reducing tumor burden within bone. International Journal of Oncology. 22: 883-90. PMID 12632083 DOI: 10.3892/Ijo.22.4.883  0.317
2002 Duque G, El Abdaimi K, Macoritto M, Miller MM, Kremer R. Estrogens (E2) regulate expression and response of 1,25-dihydroxyvitamin D3 receptors in bone cells: changes with aging and hormone deprivation. Biochemical and Biophysical Research Communications. 299: 446-54. PMID 12445821 DOI: 10.1016/S0006-291X(02)02657-8  0.409
2002 Saucier C, Papavasiliou V, Palazzo A, Naujokas MA, Kremer R, Park M. Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis. Oncogene. 21: 1800-11. PMID 11896612 DOI: 10.1038/Sj.Onc.1205261  0.332
2001 Zimmerman DR, Reinhardt TA, Kremer R, Beitz DC, Reddy GS, Horst RL. Calcitroic acid is a major catabolic metabolite in the metabolism of 1α-dihydroxyvitamin D2 Archives of Biochemistry and Biophysics. 392: 14-22. PMID 11469789 DOI: 10.1006/Abbi.2001.2419  0.37
2001 Solomon C, Macoritto M, Gao X, White JH, Kremer R. The unique tryptophan residue of the vitamin D receptor is critical for ligand binding and transcriptional activation. Journal of Bone and Mineral Research. 16: 39-45. PMID 11149488 DOI: 10.1359/Jbmr.2001.16.1.39  0.694
2001 Solomon C, White JH, Rhim JS, Kremer R. Vitamin D Resistance in RAS-Transformed Keratinocytes: Mechanism and Reversal Strategies Radiation Research. 155: 156-162. PMID 11121228 DOI: 10.1667/0033-7587(2001)155[0156:Vdrirt]2.0.Co;2  0.699
1999 Solomon C, White JH, Kremer R. Mitogen-activated protein kinase inhibits 1,25-dihydroxyvitamin D3- dependent signal transduction by phosphorylating human retinoid X receptor α Journal of Clinical Investigation. 103: 1729-1735. PMID 10377179 DOI: 10.1172/Jci6871  0.436
1996 Jones G, Byford V, Makin HL, Kremer R, Rice RH, deGraffenried LA, Knutson JC, Bishop CW. Anti-proliferative activity and target cell catabolism of the vitamin D analog 1 alpha,24(S)-(OH)2D2 in normal and immortalized human epidermal cells. Biochemical Pharmacology. 52: 133-40. PMID 8678897 DOI: 10.1016/0006-2952(96)00173-6  0.444
1996 Kremer R, Sebag M, Champigny C, Meerovitch K, Hendy GN, White J, Goltzman D. Identification and characterization of 1,25-dihydroxyvitamin D3-responsive repressor sequences in the rat parathyroid hormone-related peptide gene. Journal of Biological Chemistry. 271: 16310-16316. PMID 8663213 DOI: 10.1074/Jbc.271.27.16310  0.439
1996 Masuda S, Byford V, Kremer R, Makin HLJ, Kubodera N, Nishii Y, Okazaki A, Okano T, Kobayashi T, Jones G. In Vitro Metabolism of the Vitamin D Analog, 22-Oxacalcitriol, Using Cultured Osteosarcoma, Hepatoma, and Keratinocyte Cell Lines Journal of Biological Chemistry. 271: 8700-8708. PMID 8621502 DOI: 10.1074/Jbc.271.15.8700  0.392
1996 Masuda S, Okano T, Kobayashi T, Makin HLJ, Kremer R, Sato K, Nishii Y, Jones G. Target cell metabolism of 2β-(3-hydroxypropoxy)-1α, 25-dihydroxyvitamin D3 (ED-71) Osteoporosis International. 6: 105-105. DOI: 10.1007/Bf02499959  0.324
1995 Dilworth FJ, Scott I, Green A, Strugnell S, Guo Y, Roberts EA, Kremer R, Calverley MJ, Makin HLJ, Jones G. Different mechanisms of hydroxylation site selection by liver and kidney cytochrome P450 species (CYP27 and CYP24) involved in vitamin D metabolism. Journal of Biological Chemistry. 270: 16766-16774. PMID 7622489 DOI: 10.1074/Jbc.270.28.16766  0.376
1995 Yu J, Papavasiliou V, Rhim J, Goltzman D, Kremer R. Vitamin D analogs: new therapeutic agents for the treatment of squamous cancer and its associated hypercalcemia. Anti-Cancer Drugs. 6: 101-108. DOI: 10.1097/00001813-199502000-00012  0.483
1994 Sebag M, Gulliver W, Kremer R. Effects of 1,25 dihydroxyvitamin D3 and calcium on growth and differentiation on c-fos and P53 gene expression in normal human keratinocytes Journal of Investigative Dermatology. 103: 323-329. PMID 8077697 DOI: 10.1111/1523-1747.Ep12394802  0.411
1994 Sebag M, Henderson J, Goltzman D, Kremer R. Regulation of parathyroid hormone-related peptide production in normal human mammary epithelial cells in vitro American Journal of Physiology - Cell Physiology. 267: C723-C730. PMID 7943200 DOI: 10.1152/Ajpcell.1994.267.3.C723  0.379
1993 Haq M, Kremer R, Goltzman D, Rabbani SA. A vitamin D analogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo Journal of Clinical Investigation. 91: 2416-2422. PMID 8514854 DOI: 10.1172/Jci116475  0.406
1992 Henderson JE, Kremer R, Rhim JS, Goltzman D. Identification and functional characterization of adenylate cyclase-linked receptors for parathyroid hormone-like peptides on immortalized human keratinocytes Endocrinology. 130: 449-457. PMID 1309343 DOI: 10.1210/Endo.130.1.1309343  0.359
1991 Kremer R, Karaplis AC, Henderson J, Gulliver W, Banville D, Hendy GN, Goltzman D. Regulation of parathyroid hormone-like peptide in cultured normal human keratinocytes: Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion Journal of Clinical Investigation. 87: 884-893. PMID 1999499 DOI: 10.1172/Jci115094  0.382
1982 Kremer R, Goltzman D. Parathyroid hormone stimulates mammalian renal 25-hydroxyvitamin D3-1α-hydroxylase in vitro Endocrinology. 110: 294-296. PMID 7053991 DOI: 10.1210/Endo-110-1-294  0.379
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