Joel M. Friedman - Publications

Physiology & Biophysics Albert Einstein College of Medicine, New York, New York, United States 

352 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Costa-Orlandi CB, Martinez LR, Bila NM, Friedman JM, Friedman AJ, Mendes-Giannini MJS, Nosanchuk JD. Nitric Oxide-Releasing Nanoparticles Are Similar to Efinaconazole in Their Capacity to Eradicate Biofilms. Frontiers in Cellular and Infection Microbiology. 11: 684150. PMID 34336712 DOI: 10.3389/fcimb.2021.684150  1
2021 Tar MT, Friedman JM, Draganski A, Davies KP. Topically delivered nitric oxide acts synergistically with an orally administered PDE5 inhibitor in eliciting an erectile response in a rat model of radical prostatectomy. International Journal of Impotence Research. PMID 34017115 DOI: 10.1038/s41443-021-00451-6  1
2021 Wang J, Dey A, Kramer AH, Miao Y, Liu J, Baker L, Friedman JM, Nacharaju P, Chuck RS, Zhang C, Sharp DJ. A Novel Therapeutic Approach to Corneal Alkaline Burn Model by Targeting Fidgetin-Like 2, a Microtubule Regulator. Translational Vision Science & Technology. 10: 17. PMID 33510956 DOI: 10.1167/tvst.10.1.17  1
2021 Adusumilli NC, Mordorski B, Nosanchuk J, Friedman JM, Friedman AJ. Curcumin nanoparticles as a photoprotective adjuvant. Experimental Dermatology. PMID 33450110 DOI: 10.1111/exd.14282  1
2020 Williams AT, Muller CR, Govender K, Navati MS, Friedman AJ, Friedman JM, Cabrales P. Control of systemic inflammation throughearly nitric oxide supplementation with nitric oxide releasing nanoparticles. Free Radical Biology & Medicine. PMID 33011274 DOI: 10.1016/j.freeradbiomed.2020.09.025  1
2020 Adusumilli NC, Zhang D, Friedman JM, Friedman AJ. Harnessing nitric oxide for preventing, limiting and treating the severe pulmonary consequences of COVID-19. Nitric Oxide : Biology and Chemistry. PMID 32681986 DOI: 10.1016/j.niox.2020.07.003  1
2020 Cleare LG, Li KL, Abuzeid WM, Nacharaju P, Friedman JM, Nosanchuk JD. NO : Nitric Oxide in Nanotherapeutics to Combat Emerging Fungal Pathogen . Journal of Fungi (Basel, Switzerland). 6. PMID 32545506 DOI: 10.3390/jof6020085  1
2020 Karakus S, Musicki B, Navati MS, Friedman JM, Davies KP, Burnett AL. NO-releasing nanoparticles ameliorate detrusor overactivity in transgenic sickle cell mice via restored NO/ROCK signaling. The Journal of Pharmacology and Experimental Therapeutics. PMID 32144123 DOI: 10.1124/jpet.119.264697  1
2019 Navati MS, Lucas A, Liong C, Barros M, Jayadeva JT, Friedman JM, Cabrales P. Reducing Ischemia/Reperfusion Injury by the Targeted Delivery of Nitric Oxide from Magnetic-Field-Induced Localization of -Nitrosothiol-Coated Paramagnetic Nanoparticles. Acs Applied Bio Materials. 2: 2907-2919. PMID 35030784 DOI: 10.1021/acsabm.9b00282  1
2019 Yang C, Mavelli GV, Nacharaju P, Li K, Cleare LG, Nosanchuk JD, Friedman JM, Abuzeid WM. Novel nitric oxide-generating platform using manuka honey as an anti-biofilm strategy in chronic rhinosinusitis. International Forum of Allergy & Rhinology. PMID 31834677 DOI: 10.1002/alr.22472  1
2019 Girish VM, Liang H, Aguilan JT, Nosanchuk JD, Friedman JM, Nacharaju P. Anti-biofilm activity of garlic extract loaded nanoparticles. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 31085344 DOI: 10.1016/j.nano.2019.04.012  1
2018 Krausz AE, Adler BL, Makdisi J, Schairer D, Rosen J, Landriscina A, Navati M, Alfieri A, Friedman JM, Nosanchuk JD, Rodriguez-Gabin A, Ye KQ, McDaid HM, Friedman AJ. Nanoparticle-Encapsulated Doxorubicin Demonstrates Superior Tumor Cell Kill in Triple Negative Breast Cancer Subtypes Intrinsically Resistant to Doxorubicin. Precision Nanomedicine. 1: 173-182. PMID 31032494 DOI: 10.33218/prnano1(3).181029.1  1
2018 Abuzeid WM, Girish VM, Fastenberg JH, Draganski AR, Lee AY, Nosanchuk JD, Friedman JM. Nitric oxide-releasing microparticles as a potent antimicrobial therapeutic against chronic rhinosinusitis bacterial isolates. International Forum of Allergy & Rhinology. PMID 30044542 DOI: 10.1002/alr.22185  1
2018 Costa-Orlandi CB, Mordorski B, Baltazar LM, Mendes-Giannini MJS, Friedman JM, Nosanchuk JD, Friedman AJ. Nitric Oxide Releasing Nanoparticles as a Strategy to Improve Current Onychomycosis Treatments. Journal of Drugs in Dermatology : Jdd. 17: 717-720. PMID 30005092  1
2018 Draganski A, Tar MT, Villegas G, Friedman JM, Davies KP. Topically Applied Curcumin-Loaded Nanoparticles Treat Erectile Dysfunction in a Rat Model of Type-2 Diabetes. The Journal of Sexual Medicine. 15: 645-653. PMID 29699754 DOI: 10.1016/j.jsxm.2018.03.009  1
2017 Jana S, Meng F, Hirsch RE, Friedman JM, Alayash AI. Oxidized Mutant Human Hemoglobins S and E Induce Oxidative Stress and Bioenergetic Dysfunction in Human Pulmonary Endothelial Cells. Frontiers in Physiology. 8: 1082. PMID 29311995 DOI: 10.3389/Fphys.2017.01082  1
2017 Austin TO, Matamoros AJ, Friedman JM, Friedman AJ, Nacharaju P, Yu W, Sharp DJ, Baas PW. Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration. Scientific Reports. 7: 9675. PMID 28852085 DOI: 10.1038/S41598-017-10250-Z  1
2017 Mordorski B, Costa-Orlandi CB, Baltazar LM, Carreño LJ, Landriscina A, Rosen J, Navati M, Mendes-Giannini MJS, Friedman JM, Nosanchuk JD, Friedman AJ. Topical nitric oxide releasing nanoparticles are effective in a murine model of dermal Trichophyton rubrum dermatophytosis. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28712918 DOI: 10.1016/j.nano.2017.06.018  1
2017 Zimmerman R, Tsai AG, Salazar Vázquez BY, Cabrales P, Hofmann A, Meier J, Shander A, Spahn DR, Friedman JM, Tartakovsky DM, Intaglietta M. Posttransfusion Increase of Hematocrit per se Does Not Improve Circulatory Oxygen Delivery due to Increased Blood Viscosity. Anesthesia and Analgesia. PMID 28328758 DOI: 10.1213/Ane.0000000000002008  1
2017 Draganski AR, Friedman JM, Ludescher RD. Solvent-Slaved Dynamic Processes Observed by Tryptophan Phosphorescence of Human Serum Albumin. Biophysical Journal. 112: 881-891. PMID 28297647 DOI: 10.1016/J.Bpj.2016.12.048  1
2017 Jani VP, Jelvani A, Moges S, Nacharaju P, Roche C, Dantsker D, Palmer A, Friedman JM, Cabrales P. Polyethylene Glycol Camouflaged Earthworm Hemoglobin. Plos One. 12: e0170041. PMID 28099525 DOI: 10.1371/Journal.Pone.0170041  1
2016 Hirsch RE, Sibmooh N, Fucharoen S, Friedman JM. HbE/β-thalassemia and Oxidative Stress: The Key to Pathophysiological Mechanisms & Novel Therapeutics. Antioxidants & Redox Signaling. PMID 27650096 DOI: 10.1089/Ars.2016.6806  1
2016 Zhang Z, Leong DJ, Xu L, He Z, Wang A, Navati M, Kim SJ, Hirsh DM, Hardin JA, Cobelli NJ, Friedman JM, Sun HB. Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse model. Arthritis Research & Therapy. 18: 128. PMID 27260322 DOI: 10.1186/s13075-016-1025-y  1
2016 Navati MS, Chung W, Friedman JM. Trehalose-Based Glassy Matrices as an Effective Tool to Trap Short-Lived Intermediates in the Nitric Oxide Dioxygenation (NOD) Reaction of Hemoglobin. The Journal of Physical Chemistry. B. PMID 27120679 DOI: 10.1021/acs.jpcb.5b12778  1
2016 Strader MB, Kassa T, Meng F, Wood FB, Hirsch RE, Friedman JM, Alayash AI. Oxidative instability of hemoglobin E (β26 Glu→Lys) is increased in the presence of free α subunits and reversed by α-hemoglobin stabilizing protein (AHSP): Relevance to HbE/β-thalassemia. Redox Biology. 8: 363-374. PMID 26995402 DOI: 10.1016/J.Redox.2016.03.004  1
2016 Liang H, Friedman JM, Nacharaju P. Fabrication of biodegradable PEG-PLA nanospheres for solubility, stabilization, and delivery of curcumin. Artificial Cells, Nanomedicine, and Biotechnology. 1-8. PMID 26924283 DOI: 10.3109/21691401.2016.1146736  1
2015 Friedman JM, Friedman AJ. Development and therapeutic applications of nitric oxide-releasing materials. Future Science Oa. 1: FSO50. PMID 28031864 DOI: 10.4155/FSO.15.50  1
2015 Liang H, Nacharaju P, Friedman A, Friedman JM. Nitric oxide generating/releasing materials. Future Science Oa. 1. PMID 26855790  1
2015 Cabrales P, Ortiz D, Friedman JM. NO supplementation for transfusion medicine and cardiovascular applications. Future Science Oa. 1. PMID 26807267 DOI: 10.4155/Fso.15.51  1
2015 Li Z, Kelly L, Heiman M, Greengard P, Friedman JM. Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake. Cell Metabolism. 22: 1059-67. PMID 26655697 DOI: 10.1016/J.Cmet.2015.10.012  1
2015 Chitty LS, Friedman JM, Langlois S. Current Controversies in Prenatal Diagnosis 2: Should a fetal exome be used in the assessment of a dysmorphic or malformed fetus? Prenatal Diagnosis. PMID 26525746 DOI: 10.1002/pd.4718  1
2015 Tanowitz HB, Machado FS, Spray DC, Friedman JM, Weiss OS, Lora JN, Nagajyothi J, Moraes DN, Garg NJ, Nunes MC, Ribeiro AL. Developments in the management of Chagas cardiomyopathy. Expert Review of Cardiovascular Therapy. 1-17. PMID 26496376 DOI: 10.1586/14779072.2015.1103648  1
2015 Zeng W, Pirzgalska RM, Pereira MM, Kubasova N, Barateiro A, Seixas E, Lu YH, Kozlova A, Voss H, Martins GG, Friedman JM, Domingos AI. Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis. Cell. 163: 84-94. PMID 26406372 DOI: 10.1016/J.Cell.2015.08.055  1
2015 Peng Y, Zeng W, Ye H, Han KH, Dharmarajan V, Novick S, Wilson IA, Griffin PR, Friedman JM, Lerner RA. A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions. Chemistry & Biology. 22: 1134-43. PMID 26278185 DOI: 10.1016/J.Chembiol.2015.07.011  1
2015 Hexter A, Jones A, Joe H, Heap L, Smith MJ, Wallace AJ, Halliday D, Parry A, Taylor A, Raymond L, Shaw A, Afridi S, Obholzer R, Axon P, King AT, ... Friedman JM, et al. Clinical and molecular predictors of mortality in neurofibromatosis 2: a UK national analysis of 1192 patients. Journal of Medical Genetics. PMID 26275417 DOI: 10.1136/jmedgenet-2015-103290  1
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Corrigendum to "Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression"[Mol Metab 4 (2015) 392-405]. Molecular Metabolism. 4: 592. PMID 26266092 DOI: 10.1016/J.Molmet.2015.05.004  1
2015 Nectow AR, Ekstrand MI, Friedman JM. Molecular characterization of neuronal cell types based on patterns of projection with Retro-TRAP. Nature Protocols. 10: 1319-27. PMID 26247298 DOI: 10.1038/Nprot.2015.087  1
2015 Qin M, Landriscina A, Rosen J, Wei G, Kao S, Olcott W, Agak GW, Paz KB, Bonventre J, Clendaniel A, Harper S, Adler B, Krausz A, Friedman J, Nosanchuk J, et al. Nitric Oxide Releasing Nanoparticles Prevent Propionibacterium acnes Induced Inflammation by both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response. The Journal of Investigative Dermatology. PMID 26172313 DOI: 10.1038/Jid.2015.277  1
2015 Reefhuis J, Devine O, Friedman JM, Louik C, Honein MA. Specific SSRIs and birth defects: Bayesian analysis to interpret new data in the context of previous reports. Bmj (Clinical Research Ed.). 351: h3190. PMID 26156519 DOI: 10.1136/bmj.h3190  1
2015 Zeng W, Lu YH, Lee J, Friedman JM. Reanalysis of parabiosis of obesity mutants in the age of leptin. Proceedings of the National Academy of Sciences of the United States of America. PMID 26150485 DOI: 10.1073/Pnas.1510378112  1
2015 Ning X, Farschtschi S, Jones A, Kehrer-Sawatzki H, Mautner VF, Friedman JM. Growth in Neurofibromatosis 1 Microdeletion Patients. Clinical Genetics. PMID 26111455 DOI: 10.1111/cge.12632  1
2015 Friedman JM. Editorial. Life Sciences. PMID 26092482 DOI: 10.1016/j.lfs.2015.06.002  1
2015 Adam S, Friedman JM. Individual DNA samples and health information sold by 23andMe. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 26087174 DOI: 10.1038/gim.2015.82  1
2015 Battula KK, Nappanveettil G, Nakanishi S, Kuramoto T, Friedman JM, Kalashikam RR. Genetic Relatedness of WNIN and WNIN/Ob with Major Rat Strains in Biomedical Research. Biochemical Genetics. 53: 132-40. PMID 25991561 DOI: 10.1007/s10528-015-9679-8  1
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression. Molecular Metabolism. 4: 392-405. PMID 25973387 DOI: 10.1016/J.Molmet.2015.02.002  1
2015 Boycott K, Hartley T, Adam S, Bernier F, Chong K, Fernandez BA, Friedman JM, Geraghty MT, Hume S, Knoppers BM, Laberge AM, Majewski J, Mendoza-Londono R, Meyn MS, Michaud JL, et al. The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists. Journal of Medical Genetics. 52: 431-7. PMID 25951830 DOI: 10.1136/Jmedgenet-2015-103144  1
2015 Stanley SA, Sauer J, Kane RS, Dordick JS, Friedman JM. Corrigendum: Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles. Nature Medicine. 21: 537. PMID 25951532 DOI: 10.1038/Nm0515-537B  1
2015 Jett K, Nguyen R, Arman D, Birch P, Chohan H, Farschtschi S, Fuensterer C, Kluwe L, Friedman JM, Mautner VF. Quantitative associations of scalp and body subcutaneous neurofibromas with internal plexiform tumors in neurofibromatosis 1. American Journal of Medical Genetics. Part A. 167: 1518-24. PMID 25900062 DOI: 10.1002/ajmg.a.37068  1
2015 Samuels ME, Friedman JM. Genetic mosaics and the germ line lineage. Genes. 6: 216-37. PMID 25898403 DOI: 10.3390/genes6020216  1
2015 Charafeddine RA, Makdisi J, Schairer D, O'Rourke BP, Diaz-Valencia JD, Chouake J, Kutner A, Krausz A, Adler B, Nacharaju P, Liang H, Mukherjee S, Friedman JM, Friedman A, Nosanchuk JD, et al. Fidgetin-Like 2: A Microtubule-Based Regulator of Wound Healing. The Journal of Investigative Dermatology. PMID 25756798 DOI: 10.1038/jid.2015.94  1
2015 Glueck CJ, Friedman J, Hafeez A, Hassan A, Wang P. Testosterone therapy, thrombophilia, and hospitalization for deep venous thrombosis-pulmonary embolus, an exploratory, hypothesis-generating study. Medical Hypotheses. 84: 341-3. PMID 25648660 DOI: 10.1016/j.mehy.2015.01.020  1
2015 Filges I, Manokhina I, Peñaherrera MS, McFadden DE, Louie K, Nosova E, Friedman JM, Robinson WP. Recurrent triploidy due to a failure to complete maternal meiosis II: whole-exome sequencing reveals candidate variants. Molecular Human Reproduction. 21: 339-46. PMID 25504873 DOI: 10.1093/molehr/gau112  1
2015 Stanley SA, Sauer J, Kane RS, Dordick JS, Friedman JM. Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles. Nature Medicine. 21: 92-8. PMID 25501906 DOI: 10.1038/Nm.3730  1
2015 Friedman JM, Mantzoros CS. 20 years of leptin: from the discovery of the leptin gene to leptin in our therapeutic armamentarium. Metabolism: Clinical and Experimental. 64: 1-4. PMID 25497341 DOI: 10.1016/J.Metabol.2014.10.023  1
2015 Mordorski B, Pelgrift R, Adler B, Krausz A, da Costa Neto AB, Liang H, Gunther L, Clendaniel A, Harper S, Friedman JM, Nosanchuk JD, Nacharaju P, Friedman AJ. S-nitrosocaptopril nanoparticles as nitric oxide-liberating and transnitrosylating anti-infective technology. Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 283-91. PMID 25461287 DOI: 10.1016/j.nano.2014.09.017  1
2015 Roche CJ, Talwar A, Palmer AF, Cabrales P, Gerfen G, Friedman JM. Evaluating the capacity to generate and preserve nitric oxide bioactivity in highly purified earthworm erythrocruorin: a giant polymeric hemoglobin with potential blood substitute properties. The Journal of Biological Chemistry. 290: 99-117. PMID 25371199 DOI: 10.1074/Jbc.M114.583260  1
2015 Krausz AE, Adler BL, Cabral V, Navati M, Doerner J, Charafeddine RA, Chandra D, Liang H, Gunther L, Clendaniel A, Harper S, Friedman JM, Nosanchuk JD, Friedman AJ. Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent. Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 195-206. PMID 25240595 DOI: 10.1016/J.Nano.2014.09.004  1
2015 Berkunsky I, Simoy MV, Cepeda RE, Marinelli C, Kacoliris FP, Daniele G, Cortelezzi A, Díaz-Luque JA, Friedman JM, Aramburú RM. Assessing the use of forest islands by parrot species in a neotropical savanna | Évaluation de l'utilisation d'îles forestières par des espèces de perroquets dans une savane néotropicale Avian Conservation and Ecology. 10. DOI: 10.5751/ACE-00753-100111  1
2015 Meko DM, Friedman JM, Touchan R, Edmondson JR, Griffin ER, Scott JA. Alternative standardization approaches to improving streamflow reconstructions with ring-width indices of riparian trees Holocene. 25: 1093-1101. DOI: 10.1177/0959683615580181  1
2015 Friedman JM, Vincent KR, Griffin ER, Scott ML, Shafroth PB, Auble GT. Processes of arroyo filling in northern New Mexico, USA Bulletin of the Geological Society of America. 127: 621-640. DOI: 10.1130/B31046.1  1
2015 Mcshane RR, Auerbach DA, Friedman JM, Auble GT, Shafroth PB, Merigliano MF, Scott ML, Poff NL. Distribution of invasive and native riparian woody plants across the western USA in relation to climate, river flow, floodplain geometry and patterns of introduction Ecography. 38: 1254-1265. DOI: 10.1111/Ecog.01285  1
2015 Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Corrigendum to "Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression"[Mol Metab 4 (2015) 392-405] Molecular Metabolism. DOI: 10.1016/j.molmet.2015.05.004  1
2015 Sackeyfio R, Bernstein JL, Kutler DI, Friedman JM, Spector JA. Reconstruction of a pathologic mandibular fracture in a patient with pycnodysostosis using a free osteocutaneous fibula flap: A case report Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. DOI: 10.1016/j.ajoms.2015.03.010  1
2015 Nemzer LR, Navati MS, Friedman JM. Imprisoned lightning: charge transport in trehalose-derived sugar glasses Ionics. DOI: 10.1007/s11581-015-1410-6  1
2015 Liu S, Chen Y, Friedman JM, Hati JHA, Fang G. Use of 2H and 18O stable isotopes to investigate water sources for different ages of Populus euphratica along the lower Heihe River Ecological Research. DOI: 10.1007/s11284-015-1270-6  1
2015 Mandinach EB, Friedman JM, Gummer ES. How can schools of education help to build educators' capacity to use data? A systemic view of the issue Teachers College Record. 117: 1-50.  1
2014 Daston GP, Beyer BK, Carney EW, Chapin RE, Friedman JM, Piersma AH, Rogers JM, Scialli AR. Exposure-based validation list for developmental toxicity screening assays. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 101: 423-8. PMID 25475026 DOI: 10.1002/bdrb.21132  1
2014 Bove R, Alwan S, Friedman JM, Hellwig K, Houtchens M, Koren G, Lu E, McElrath TF, Smyth P, Tremlett H, Sadovnick AD. Management of multiple sclerosis during pregnancy and the reproductive years: a systematic review. Obstetrics and Gynecology. 124: 1157-68. PMID 25415167 DOI: 10.1097/01.Aoa.0000472705.96338.58  1
2014 Stavas MJ, Shinohara ET, Attia A, Ning MS, Friedman JM, Cmelak AJ. Short course high dose radiotherapy in the treatment of anaplastic thyroid carcinoma. Journal of Thyroid Research. 2014: 764281. PMID 25379320 DOI: 10.1155/2014/764281  1
2014 Tan K, Knight ZA, Friedman JM. Ablation of AgRP neurons impairs adaption to restricted feeding. Molecular Metabolism. 3: 694-704. PMID 25352998 DOI: 10.1016/J.Molmet.2014.07.002  1
2014 Tar M, Cabrales P, Navati M, Adler B, Nacharaju P, Friedman AJ, Friedman J, Davies KP. Topically applied NO-releasing nanoparticles can increase intracorporal pressure and elicit spontaneous erections in a rat model of radical prostatectomy. The Journal of Sexual Medicine. 11: 2903-14. PMID 25302850 DOI: 10.1111/Jsm.12705  1
2014 Friedman JM, Stavas MJ, Cmelak AJ. Clinical and scientific impact of human papillomavirus on head and neck cancer. World Journal of Clinical Oncology. 5: 781-91. PMID 25302178 DOI: 10.5306/wjco.v5.i4.781  1
2014 Elliott JE, Friedman JM, Futral JE, Goodman RD, Lovering AT. Sildenafil, nifedipine and acetazolamide do not allow for blood flow through intrapulmonary arteriovenous anastomoses during exercise while breathing 100% oxygen. Experimental Physiology. 99: 1636-47. PMID 25261497 DOI: 10.1113/Expphysiol.2014.081562  1
2014 Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, et al. Update from the 2013 International Neurofibromatosis Conference. American Journal of Medical Genetics. Part A. 164: 2969-78. PMID 25255738 DOI: 10.1002/Ajmg.A.36754  1
2014 Saito N, Sakakibara K, Sato T, Friedman JM, Kufe DW, VonHoff DD, Kawabe T. CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway. Molecular Cancer Therapeutics. 13: 3013-23. PMID 25253782 DOI: 10.1158/1535-7163.MCT-14-0064  1
2014 Knight ZA, Schmidt SF, Birsoy K, Tan K, Friedman JM. A critical role for mTORC1 in erythropoiesis and anemia. Elife. 3: e01913. PMID 25201874 DOI: 10.7554/Elife.01913  1
2014 Filges I, Friedman JM. Exome sequencing for gene discovery in lethal fetal disorders - harnessing the value of extreme phenotypes. Prenatal Diagnosis. PMID 25046514 DOI: 10.1002/pd.4464  1
2014 Liong C, Ortiz D, Ao-ieong E, Navati MS, Friedman JM, Cabrales P. Localized increase of tissue oxygen tension by magnetic targeted drug delivery. Nanotechnology. 25: 265102. PMID 24920392 DOI: 10.1088/0957-4484/25/26/265102  1
2014 Beaulieu CL, Majewski J, Schwartzentruber J, Samuels ME, Fernandez BA, Bernier FP, Brudno M, Knoppers B, Marcadier J, Dyment D, Adam S, Bulman DE, Jones SJ, Avard D, Nguyen MT, ... Friedman JM, et al. FORGE Canada Consortium: outcomes of a 2-year national rare-disease gene-discovery project. American Journal of Human Genetics. 94: 809-17. PMID 24906018 DOI: 10.1016/J.Ajhg.2014.05.003  1
2014 Ekstrand MI, Nectow AR, Knight ZA, Latcha KN, Pomeranz LE, Friedman JM. Molecular profiling of neurons based on connectivity. Cell. 157: 1230-42. PMID 24855954 DOI: 10.1016/J.Cell.2014.03.059  1
2014 Williams WI, Friedman JM, Gaskin JF, Norton AP. Hybridization of an invasive shrub affects tolerance and resistance to defoliation by a biological control agent. Evolutionary Applications. 7: 381-93. PMID 24665340 DOI: 10.1111/eva.12134  1
2014 Friedman JM, Adam S. Genetic diagnosis through whole-exome sequencing. The New England Journal of Medicine. 370: 1067-8. PMID 24620874 DOI: 10.1056/NEJMc1315908#SA2  1
2014 Domingos AI, Vaynshteyn J, Sordillo A, Friedman JM. The reward value of sucrose in leptin-deficient obese mice. Molecular Metabolism. 3: 73-80. PMID 24567906 DOI: 10.1016/J.Molmet.2013.10.007  1
2014 Demos MK, van Karnebeek CD, Ross CJ, Adam S, Shen Y, Zhan SH, Shyr C, Horvath G, Suri M, Fryer A, Jones SJ, Friedman JM. A novel recurrent mutation in ATP1A3 causes CAPOS syndrome. Orphanet Journal of Rare Diseases. 9: 15. PMID 24468074 DOI: 10.1186/1750-1172-9-15  1
2014 Saito Y, Saito H, Liang G, Friedman JM. Epigenetic alterations and microRNA misexpression in cancer and autoimmune diseases: a critical review. Clinical Reviews in Allergy & Immunology. 47: 128-35. PMID 24362548 DOI: 10.1007/s12016-013-8401-z  1
2014 McKinnon ML, Rozmus J, Fung SY, Hirschfeld AF, Del Bel KL, Thomas L, Marr N, Martin SD, Marwaha AK, Priatel JJ, Tan R, Senger C, Tsang A, Prendiville J, Junker AK, ... Friedman JM, et al. Combined immunodeficiency associated with homozygous MALT1 mutations. The Journal of Allergy and Clinical Immunology. 133: 1458-62, 1462.e1-7. PMID 24332264 DOI: 10.1016/j.jaci.2013.10.045  1
2014 Walsh JJ, Friedman AK, Sun H, Heller EA, Ku SM, Juarez B, Burnham VL, Mazei-Robison MS, Ferguson D, Golden SA, Koo JW, Chaudhury D, Christoffel DJ, Pomeranz L, Friedman JM, et al. Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway. Nature Neuroscience. 17: 27-9. PMID 24270188 DOI: 10.1038/Nn.3591  1
2014 Tucker T, Zahir FR, Griffith M, Delaney A, Chai D, Tsang E, Lemyre E, Dobrzeniecka S, Marra M, Eydoux P, Langlois S, Hamdan FF, Michaud JL, Friedman JM. Single exon-resolution targeted chromosomal microarray analysis of known and candidate intellectual disability genes. European Journal of Human Genetics : Ejhg. 22: 792-800. PMID 24253858 DOI: 10.1038/Ejhg.2013.248  1
2014 Nguyen R, Jett K, Harris GJ, Cai W, Friedman JM, Mautner VF. Benign whole body tumor volume is a risk factor for malignant peripheral nerve sheath tumors in neurofibromatosis type 1. Journal of Neuro-Oncology. 116: 307-13. PMID 24166582 DOI: 10.1007/S11060-013-1293-1  1
2014 Filges I, Nosova E, Bruder E, Tercanli S, Townsend K, Gibson WT, Röthlisberger B, Heinimann K, Hall JG, Gregory-Evans CY, Wasserman WW, Miny P, Friedman JM. Exome sequencing identifies mutations in KIF14 as a novel cause of an autosomal recessive lethal fetal ciliopathy phenotype. Clinical Genetics. 86: 220-8. PMID 24128419 DOI: 10.1111/cge.12301  1
2014 Sanchez DA, Schairer D, Tuckman-Vernon C, Chouake J, Kutner A, Makdisi J, Friedman JM, Nosanchuk JD, Friedman AJ. Amphotericin B releasing nanoparticle topical treatment of Candida spp. in the setting of a burn wound. Nanomedicine : Nanotechnology, Biology, and Medicine. 10: 269-77. PMID 23770066 DOI: 10.1016/j.nano.2013.06.002  1
2014 Lohn Z, Adam S, Birch PH, Friedman JM. Incidental findings from clinical genome-wide sequencing: a review. Journal of Genetic Counseling. 23: 463-73. PMID 23709124 DOI: 10.1007/s10897-013-9604-4  1
2014 Griffin ER, Perignon MC, Friedman JM, Tucker GE. Effects of woody vegetation on overbank sand transport during a large flood, Rio Puerco, New Mexico Geomorphology. 207: 30-50. DOI: 10.1016/J.Geomorph.2013.10.025  1
2014 Friedman JM, Hanson JW. Clinical Teratology Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.05509-4  1
2014 Friedman JM, Weber-Schöndorfer C. Antineoplastic drugs Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment: Third Edition. 373-399. DOI: 10.1016/B978-0-12-408078-2.00014-7  1
2013 Tucker T, Giroux S, Clément V, Langlois S, Friedman JM, Rousseau F. Prevalence of selected genomic deletions and duplications in a French-Canadian population-based sample of newborns. Molecular Genetics & Genomic Medicine. 1: 87-97. PMID 24498606 DOI: 10.1002/Mgg3.12  1
2013 Domingos AI, Sordillo A, Dietrich MO, Liu ZW, Tellez LA, Vaynshteyn J, Ferreira JG, Ekstrand MI, Horvath TL, de Araujo IE, Friedman JM. Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar. Elife. 2: e01462. PMID 24381247 DOI: 10.7554/Elife.01462  1
2013 Li Z, Ceccarini G, Eisenstein M, Tan K, Friedman JM. Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor. Molecular Metabolism. 2: 364-75. PMID 24327953 DOI: 10.1016/J.Molmet.2013.07.007  1
2013 Kalashikam RR, Battula KK, Kirlampalli V, Friedman JM, Nappanveettil G. Obese locus in WNIN/obese rat maps on chromosome 5 upstream of leptin receptor. Plos One. 8: e77679. PMID 24204914 DOI: 10.1371/journal.pone.0077679  1
2013 Roche CJ, Dantsker D, Heller ER, Sabat JE, Friedman JM. Reverse micelles as a tool for probing solvent modulation of protein dynamics: Reverse micelle encapsulated hemoglobin. Chemical Physics. 430: 88-97. PMID 24039330 DOI: 10.1016/j.chemphys.2013.04.006  1
2013 Friedman JM. A conversation with NYSDA President Joel M. Friedman, D.D.S. The New York State Dental Journal. 79: 26-8. PMID 24027893  1
2013 Townsend A, Adam S, Birch PH, Friedman JM. Paternalism and the ACMG recommendations on genomic incidental findings: patients seen but not heard. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 751-2. PMID 24008256 DOI: 10.1038/gim.2013.105  1
2013 Thorpe PG, Gilboa SM, Hernandez-Diaz S, Lind J, Cragan JD, Briggs G, Kweder S, Friedman JM, Mitchell AA, Honein MA. Medications in the first trimester of pregnancy: most common exposures and critical gaps in understanding fetal risk. Pharmacoepidemiology and Drug Safety. 22: 1013-8. PMID 23893932 DOI: 10.1002/Pds.3495  1
2013 Roche CJ, Cassera MB, Dantsker D, Hirsch RE, Friedman JM. Generating S-nitrosothiols from hemoglobin: mechanisms, conformational dependence, and physiological relevance. The Journal of Biological Chemistry. 288: 22408-25. PMID 23775069 DOI: 10.1074/Jbc.M113.482679  1
2013 Armstrong L, Jett K, Birch P, Kendler DL, McKay H, Tsang E, Stevenson DA, Hanley DA, Egeli D, Burrows M, Friedman JM. The generalized bone phenotype in children with neurofibromatosis 1: a sibling matched case-control study. American Journal of Medical Genetics. Part A. 161: 1654-61. PMID 23713011 DOI: 10.1002/Ajmg.A.36001  1
2013 Friedman JM. A conversation with Jeffrey M. Friedman by Ushma S. Neill. The Journal of Clinical Investigation. 123: 529-30. PMID 23598296 DOI: 10.1172/JCI68394  0.01
2013 Stevenson DA, Little D, Armstrong L, Crawford AH, Eastwood D, Friedman JM, Greggi T, Gutierrez G, Hunter-Schaedle K, Kendler DL, Kolanczyk M, Monsell F, Oetgen M, Richards BS, Schindeler A, et al. Approaches to treating NF1 tibial pseudarthrosis: consensus from the Children's Tumor Foundation NF1 Bone Abnormalities Consortium. Journal of Pediatric Orthopedics. 33: 269-75. PMID 23482262 DOI: 10.1097/Bpo.0B013E31828121B8  1
2013 Dias C, McDonald A, Sincan M, Rupps R, Markello T, Salvarinova R, Santos RF, Menghrajani K, Ahaghotu C, Sutherland DP, Fortuno ES, Kollmann TR, Demos M, Friedman JM, Speert DP, et al. Recurrent subacute post-viral onset of ataxia associated with a PRF1 mutation. European Journal of Human Genetics : Ejhg. 21: 1232-9. PMID 23443029 DOI: 10.1038/Ejhg.2013.20  1
2013 Li Z, Schmidt SF, Friedman JM. Developmental role for endocannabinoid signaling in regulating glucose metabolism and growth. Diabetes. 62: 2359-67. PMID 23423572 DOI: 10.2337/Db12-0901  1
2013 Zhu JL, Hasle H, Correa A, Schendel D, Friedman JM, Olsen J, Rasmussen SA. Hospitalizations among people with Down syndrome: a nationwide population-based study in Denmark. American Journal of Medical Genetics. Part A. 161: 650-7. PMID 23404922 DOI: 10.1002/Ajmg.A.35711  1
2013 Murdock D, Salit J, Stoffel M, Friedman JM, Pe'er I, Breslow JL, Bonnen PE. Longitudinal study shows increasing obesity and hyperglycemia in micronesia. Obesity (Silver Spring, Md.). 21: E421-7. PMID 23404778 DOI: 10.1002/Oby.20041  1
2013 Peters SL, Lind JN, Humphrey JR, Friedman JM, Honein MA, Tassinari MS, Moore CA, Mathis LL, Broussard CS. Safe lists for medications in pregnancy: inadequate evidence base and inconsistent guidance from Web-based information, 2011. Pharmacoepidemiology and Drug Safety. 22: 324-8. PMID 23359404 DOI: 10.1002/pds.3410  1
2013 Nguyen R, Mir TS, Kluwe L, Jett K, Kentsch M, Mueller G, Kehrer-Sawatzki H, Friedman JM, Mautner VF. Cardiac characterization of 16 patients with large NF1 gene deletions. Clinical Genetics. 84: 344-9. PMID 23278345 DOI: 10.1111/cge.12072  1
2013 Cabrales P, Friedman JM. HBOC vasoactivity: interplay between nitric oxide scavenging and capacity to generate bioactive nitric oxide species. Antioxidants & Redox Signaling. 18: 2284-97. PMID 23249305 DOI: 10.1089/Ars.2012.5099  1
2013 Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, ... Friedman JM, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 493: 532-6. PMID 23235832 DOI: 10.1038/Nature11713  1
2013 Schnabel C, Jett K, Friedman JM, Frieling I, Kruse HP, Mautner V. Effect of vitamin D3 treatment on bone density in neurofibromatosis 1 patients: a retrospective clinical study. Joint, Bone, Spine : Revue Du Rhumatisme. 80: 315-9. PMID 23021159 DOI: 10.1016/j.jbspin.2012.07.010  1
2013 Friedman JM, Hagander L, Hughes CD, Nash KA, Linden AF, Blossom J, Meara JG. Distance to hospital and utilization of surgical services in Haiti: do children, delivering mothers, and patients with emergent surgical conditions experience greater geographical barriers to surgical care? The International Journal of Health Planning and Management. 28: 248-56. PMID 22936638 DOI: 10.1002/hpm.2134  1
2013 Zhu JL, Hasle H, Correa A, Schendel D, Friedman JM, Olsen J, Rasmussen SA. Survival among people with Down syndrome: a nationwide population-based study in Denmark. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 64-9. PMID 22878506 DOI: 10.1038/Gim.2012.93  1
2013 Schnabel C, Jett K, Friedman JM, Frieling I, Kruse HP, Mautner V. Effect of vitamin D3 on bone density among patients with a neurofibromatosis type 1: A retrospective clinical study | Effet de la vitamine D3 sur la densité osseuse chez les patients porteurs d'une neurofibromatose 1: Une étude clinique rétrospective Revue Du Rhumatisme (Edition Francaise). 80: 262-266. DOI: 10.1016/j.rhum.2012.09.011  1
2013 Friedman JM, Hanson JW. Clinical Teratology Emery and Rimoin's Principles and Practice of Medical Genetics. 1-39. DOI: 10.1016/B978-0-12-383834-6.00044-6  1
2013 Merigliano MF, Friedman JM, Scott ML. Tree-Ring Records of Variation in Flow and Channel Geometry Treatise On Geomorphology. 12: 145-164. DOI: 10.1016/B978-0-12-374739-6.00319-5  1
2013 Birch P, Friedman JM. Quality of life in NF1 Neurofibromatosis Type 1: Molecular and Cellular Biology. 93-103. DOI: 10.1007/978-3-642-32864-0_8  1
2013 Stansfield BK, Ingram DA, Conway SJ, Friedman JM. Molecular basis of cardiovascular abnormalities in NF1 Neurofibromatosis Type 1: Molecular and Cellular Biology. 353-366. DOI: 10.1007/978-3-642-32864-0_23  1
2013 Perignon MC, Tucker GE, Griffin ER, Friedman JM. Effects of riparian vegetation on topographic change during a large flood event, Rio Puerco, New Mexico, USA Journal of Geophysical Research: Earth Surface. 118: 1193-1209. DOI: 10.1002/Jgrf.20073  1
2012 Chouake J, Schairer D, Kutner A, Sanchez DA, Makdisi J, Blecher-Paz K, Nacharaju P, Tuckman-Vernon C, Gialanella P, Friedman JM, Nosanchuk JD, Friedman AJ. Nitrosoglutathione generating nitric oxide nanoparticles as an improved strategy for combating Pseudomonas aeruginosa-infected wounds. Journal of Drugs in Dermatology : Jdd. 11: 1471-7. PMID 23377518  1
2012 Knight ZA, Tan K, Birsoy K, Schmidt S, Garrison JL, Wysocki RW, Emiliano A, Ekstrand MI, Friedman JM. Molecular profiling of activated neurons by phosphorylated ribosome capture. Cell. 151: 1126-37. PMID 23178128 DOI: 10.1016/J.Cell.2012.10.039  1
2012 Nguyen R, Dombi E, Widemann BC, Solomon J, Fuensterer C, Kluwe L, Friedman JM, Mautner VF. Growth dynamics of plexiform neurofibromas: a retrospective cohort study of 201 patients with neurofibromatosis 1. Orphanet Journal of Rare Diseases. 7: 75. PMID 23035791 DOI: 10.1186/1750-1172-7-75  1
2012 Manzini MC, Tambunan DE, Hill RS, Yu TW, Maynard TM, Heinzen EL, Shianna KV, Stevens CR, Partlow JN, Barry BJ, Rodriguez J, Gupta VA, Al-Qudah AK, Eyaid WM, Friedman JM, et al. Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome. American Journal of Human Genetics. 91: 541-7. PMID 22958903 DOI: 10.1016/J.Ajhg.2012.07.009  1
2012 Tsang E, Rupps R, McGillivray B, Eydoux P, Marra M, Arbour L, Langlois S, Friedman JM, Zahir FR. Life-history chronicle for a patient with the recently described chromosome 4q21 microdeletion syndrome. American Journal of Medical Genetics. Part A. 158: 2606-9. PMID 22903878 DOI: 10.1002/Ajmg.A.35568  1
2012 Townsend A, Adam S, Birch PH, Lohn Z, Rousseau F, Friedman JM. "I want to know what's in Pandora's Box": comparing stakeholder perspectives on incidental findings in clinical whole genomic sequencing. American Journal of Medical Genetics. Part A. 158: 2519-25. PMID 22903777 DOI: 10.1002/ajmg.a.35554  1
2012 Chambers C, Friedman JM. OTIS special issue preface. Birth Defects Research. Part a, Clinical and Molecular Teratology. 94: 569. PMID 22847972 DOI: 10.1002/Bdra.23069  1
2012 Friedman JM. ABCDXXX: The obscenity of postmarketing surveillance for teratogenic effects. Birth Defects Research. Part a, Clinical and Molecular Teratology. 94: 670-6. PMID 22786781 DOI: 10.1002/bdra.23043  1
2012 Nacharaju P, Tuckman-Vernon C, Maier KE, Chouake J, Friedman A, Cabrales P, Friedman JM. A nanoparticle delivery vehicle for S-nitroso-N-acetyl cysteine: sustained vascular response. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 27: 150-60. PMID 22705913 DOI: 10.1016/J.Niox.2012.06.003  1
2012 Stanley SA, Gagner JE, Damanpour S, Yoshida M, Dordick JS, Friedman JM. Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. Science (New York, N.Y.). 336: 604-8. PMID 22556257 DOI: 10.1126/Science.1216753  1
2012 Roche CJ, Dantsker D, Alayash AI, Friedman JM. Enhanced nitrite reductase activity associated with the haptoglobin complexed hemoglobin dimer: functional and antioxidative implications. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 27: 32-9. PMID 22521791 DOI: 10.1016/j.niox.2012.04.002  1
2012 Yang Q, Bailey L, Clarke R, Flanders WD, Liu T, Yesupriya A, Khoury MJ, Friedman JM. Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults. The American Journal of Clinical Nutrition. 95: 1245-53. PMID 22492374 DOI: 10.3945/ajcn.111.022384  1
2012 Demanes DJ, Friedman JM, Park SJ, Steinberg ML, Hayes JK, Kamrava MR. Brachytherapy catheter spacing and stabilization technique. Brachytherapy. 11: 392-7. PMID 22436515 DOI: 10.1016/j.brachy.2012.01.010  1
2012 Blecher K, Martinez LR, Tuckman-Vernon C, Nacharaju P, Schairer D, Chouake J, Friedman JM, Alfieri A, Guha C, Nosanchuk JD, Friedman AJ. Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice. Nanomedicine : Nanotechnology, Biology, and Medicine. 8: 1364-71. PMID 22406184 DOI: 10.1016/J.Nano.2012.02.014  1
2012 Han G, Nguyen LN, Macherla C, Chi Y, Friedman JM, Nosanchuk JD, Martinez LR. Nitric oxide-releasing nanoparticles accelerate wound healing by promoting fibroblast migration and collagen deposition. The American Journal of Pathology. 180: 1465-73. PMID 22306734 DOI: 10.1016/J.Ajpath.2011.12.013  1
2012 Schairer D, Martinez LR, Blecher K, Chouake J, Nacharaju P, Gialanella P, Friedman JM, Nosanchuk JD, Friedman A. Nitric oxide nanoparticles: pre-clinical utility as a therapeutic for intramuscular abscesses. Virulence. 3: 62-7. PMID 22286699 DOI: 10.4161/Viru.3.1.18816  1
2012 Bombard Y, Palin J, Friedman JM, Veenstra G, Creighton S, Bottorff JL, Hayden MR. Beyond the patient: the broader impact of genetic discrimination among individuals at risk of Huntington disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 217-26. PMID 22231990 DOI: 10.1002/Ajmg.B.32016  1
2012 Gusev A, Shah MJ, Kenny EE, Ramachandran A, Lowe JK, Salit J, Lee CC, Levandowsky EC, Weaver TN, Doan QC, Peckham HE, McLaughlin SF, Lyons MR, Sheth VN, Stoffel M, ... Friedman JM, et al. Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population. Genetics. 190: 679-89. PMID 22135348 DOI: 10.1534/Genetics.111.134874  1
2012 Tsang E, Birch P, Friedman JM. Valuing gene testing in children with possible neurofibromatosis 1. Clinical Genetics. 82: 591-3. PMID 22014292 DOI: 10.1111/j.1399-0004.2011.01801.x  1
2012 Jasaitis A, Ouellet H, Lambry JC, Martin JL, Friedman JM, Guertin M, Vos MH. Ultrafast heme-ligand recombination in truncated hemoglobin HbO from Mycobacterium tuberculosis: A ligand cage Chemical Physics. 396: 10-16. DOI: 10.1016/J.Chemphys.2011.04.003  1
2012 Guilbault KR, Brown CS, Friedman JM, Shafroth PB. The influence of chilling requirement on the southern distribution limit of exotic Russian olive (Elaeagnus angustifolia) in western North America Biological Invasions. 14: 1711-1724. DOI: 10.1007/s10530-012-0182-4  1
2011 Friedman JM. Using genomics for birth defects epidemiology: can epigenetics cut the GxE Gordian knot? Birth Defects Research. Part a, Clinical and Molecular Teratology. 91: 986-9. PMID 22140073 DOI: 10.1002/bdra.22875  1
2011 Birsoy K, Berry R, Wang T, Ceyhan O, Tavazoie S, Friedman JM, Rodeheffer MS. Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis. Development (Cambridge, England). 138: 4709-19. PMID 21989915 DOI: 10.1242/Jcs.101436  1
2011 Friedman AJ, Blecher K, Schairer D, Tuckman-Vernon C, Nacharaju P, Sanchez D, Gialanella P, Martinez LR, Friedman JM, Nosanchuk JD. Improved antimicrobial efficacy with nitric oxide releasing nanoparticle generated S-nitrosoglutathione. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 25: 381-6. PMID 21946032 DOI: 10.1016/J.Niox.2011.09.001  1
2011 Friedman JM, Roelle JE, Cade BS. Genetic and environmental influences on leaf phenology and cold hardiness of native and introduced riparian trees. International Journal of Biometeorology. 55: 775-87. PMID 21927930 DOI: 10.1007/s00484-011-0494-6  1
2011 Bierer R, Nitta CH, Friedman J, Codianni S, de Frutos S, Dominguez-Bautista JA, Howard TA, Resta TC, Bosc LV. NFATc3 is required for chronic hypoxia-induced pulmonary hypertension in adult and neonatal mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L872-80. PMID 21908592 DOI: 10.1152/ajplung.00405.2010  1
2011 Ribeiro AC, Ceccarini G, Dupré C, Friedman JM, Pfaff DW, Mark AL. Contrasting effects of leptin on food anticipatory and total locomotor activity. Plos One. 6: e23364. PMID 21853117 DOI: 10.1371/Journal.Pone.0023364  1
2011 Sakakibara K, Saito N, Sato T, Suzuki A, Hasegawa Y, Friedman JM, Kufe DW, Vonhoff DD, Iwami T, Kawabe T. CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity. Blood. 118: 3922-31. PMID 21841164 DOI: 10.1182/blood-2011-01-333138  1
2011 Adam MP, Polifka JE, Friedman JM. Evolving knowledge of the teratogenicity of medications in human pregnancy. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 157: 175-82. PMID 21766440 DOI: 10.1002/ajmg.c.30313  1
2011 Rasmussen SA, Friedman JM. Emerging issues in teratology: an introduction. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 157: 147-9. PMID 21766432 DOI: 10.1002/ajmg.c.30305  1
2011 Friedman JM. How do we know if an exposure is actually teratogenic in humans? American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 157: 170-4. PMID 21766430 DOI: 10.1002/ajmg.c.30302  1
2011 Bonaventura C, Henkens R, Friedman J, Siburt CJ, Kraiter D, Crumbliss AL. Steric factors moderate conformational fluidity and contribute to the high proton sensitivity of Root effect hemoglobins. Biochimica Et Biophysica Acta. 1814: 1261-8. PMID 21745602 DOI: 10.1016/J.Bbapap.2011.06.012  1
2011 Qiu X, Friedman JM, Liang G. Creating a flexible multiple microRNA expression vector by linking precursor microRNAs. Biochemical and Biophysical Research Communications. 411: 276-80. PMID 21726537 DOI: 10.1016/j.bbrc.2011.06.123  1
2011 Tucker T, Riccardi VM, Brown C, Fee J, Sutcliffe M, Vielkind J, Wechsler J, Wolkenstein P, Friedman JM. S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas. Journal of Neuroscience Research. 89: 1451-60. PMID 21674567 DOI: 10.1002/jnr.22654  1
2011 Gusev A, Kenny EE, Lowe JK, Salit J, Saxena R, Kathiresan S, Altshuler DM, Friedman JM, Breslow JL, Pe'er I. DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation. American Journal of Human Genetics. 88: 706-17. PMID 21620352 DOI: 10.1016/J.Ajhg.2011.04.023  1
2011 Friedman JM. Dilate, dilute, constrict, or else in treating hemorrhage? Critical Care Medicine. 39: 1591-2. PMID 21610642 DOI: 10.1097/CCM.0b013e3182185480  1
2011 Moore RA, Warren RL, Freeman JD, Gustavsen JA, Chénard C, Friedman JM, Suttle CA, Zhao Y, Holt RA. The sensitivity of massively parallel sequencing for detecting candidate infectious agents associated with human tissue. Plos One. 6: e19838. PMID 21603639 DOI: 10.1371/Journal.Pone.0019838  1
2011 Friedman A, Blecher K, Sanchez D, Tuckman-Vernon C, Gialanella P, Friedman JM, Martinez LR, Nosanchuk JD. Susceptibility of Gram-positive and -negative bacteria to novel nitric oxide-releasing nanoparticle technology. Virulence. 2: 217-21. PMID 21577055 DOI: 10.4161/Viru.2.3.16161  1
2011 Roche CJ, Malashkevich V, Balazs TC, Dantsker D, Chen Q, Moreira J, Almo SC, Friedman JM, Hirsch RE. Structural and functional studies indicating altered redox properties of hemoglobin E: implications for production of bioactive nitric oxide. The Journal of Biological Chemistry. 286: 23452-66. PMID 21531715 DOI: 10.1074/Jbc.M110.183186  1
2011 Tucker T, Riccardi VM, Sutcliffe M, Vielkind J, Wechsler J, Wolkenstein P, Friedman JM. Different patterns of mast cells distinguish diffuse from encapsulated neurofibromas in patients with neurofibromatosis 1. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 59: 584-90. PMID 21525187 DOI: 10.1369/0022155411407340  1
2011 Nachuraju P, Friedman AJ, Friedman JM, Cabrales P. Exogenous nitric oxide prevents cardiovascular collapse during hemorrhagic shock. Resuscitation. 82: 607-13. PMID 21342744 DOI: 10.1016/J.Resuscitation.2010.12.025  1
2011 Pérez CA, Stanley SA, Wysocki RW, Havranova J, Ahrens-Nicklas R, Onyimba F, Friedman JM. Molecular annotation of integrative feeding neural circuits. Cell Metabolism. 13: 222-32. PMID 21284989 DOI: 10.1016/J.Cmet.2010.12.013  1
2011 Han G, Friedman AJ, Friedman JM. Nitric oxide releasing nanoparticle synthesis and characterization. Methods in Molecular Biology (Clifton, N.J.). 704: 187-95. PMID 21161638 DOI: 10.1007/978-1-61737-964-2_14  1
2011 Cabrales P, Han G, Nacharaju P, Friedman AJ, Friedman JM. Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide. American Journal of Physiology. Heart and Circulatory Physiology. 300: H49-56. PMID 21057038 DOI: 10.1152/Ajpheart.00665.2010  1
2011 Broussard CS, Rasmussen SA, Friedman JM. Reply American Journal of Obstetrics and Gynecology. 205: e12. DOI: 10.1016/j.ajog.2011.04.027  1
2010 Friedman JM, Portnof JE. Similar experience. The New York State Dental Journal. 76: 8. PMID 21229665  1
2010 Mihu MR, Sandkovsky U, Han G, Friedman JM, Nosanchuk JD, Martinez LR. The use of nitric oxide releasing nanoparticles as a treatment against Acinetobacter baumannii in wound infections. Virulence. 1: 62-7. PMID 21178416 DOI: 10.4161/Viru.1.2.10038  1
2010 Israel HA, Behrman DA, Friedman JM, Silberstein J. Rationale for early versus late intervention with arthroscopy for treatment of inflammatory/degenerative temporomandibular joint disorders. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. 68: 2661-7. PMID 20739111 DOI: 10.1016/j.joms.2010.05.051  1
2010 Knight ZA, Hannan KS, Greenberg ML, Friedman JM. Hyperleptinemia is required for the development of leptin resistance. Plos One. 5: e11376. PMID 20613882 DOI: 10.1371/Journal.Pone.0011376  1
2010 Cabrales P, Han G, Roche C, Nacharaju P, Friedman AJ, Friedman JM. Sustained release nitric oxide from long-lived circulating nanoparticles. Free Radical Biology & Medicine. 49: 530-8. PMID 20460149 DOI: 10.1016/J.Freeradbiomed.2010.04.034  1
2010 Stanley S, Pinto S, Segal J, Pérez CA, Viale A, DeFalco J, Cai X, Heisler LK, Friedman JM. Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically. Proceedings of the National Academy of Sciences of the United States of America. 107: 7024-9. PMID 20351287 DOI: 10.1073/Pnas.1002790107  1
2010 Martinez LR, Mihu MR, Tar M, Cordero RJ, Han G, Friedman AJ, Friedman JM, Nosanchuk JD. Demonstration of antibiofilm and antifungal efficacy of chitosan against candidal biofilms, using an in vivo central venous catheter model. The Journal of Infectious Diseases. 201: 1436-40. PMID 20331379 DOI: 10.1086/651558  1
2010 Navati MS, Friedman JM. Glass matrix-facilitated thermal reduction: a tool for probing reactions of met hemoglobin with nitrite and nitric oxide. The Journal of Physical Chemistry. B. 114: 2938-43. PMID 20146537 DOI: 10.1021/jp909425z  1
2010 Roche CJ, Friedman JM. NO reactions with sol-gel and solution phase samples of the ferric nitrite derivative of HbA. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 22: 180-90. PMID 19919854 DOI: 10.1016/j.niox.2009.11.003  1
2010 Martinez LR, Mihu MR, Han G, Frases S, Cordero RJ, Casadevall A, Friedman AJ, Friedman JM, Nosanchuk JD. The use of chitosan to damage Cryptococcus neoformans biofilms. Biomaterials. 31: 669-79. PMID 19819009 DOI: 10.1016/J.Biomaterials.2009.09.087  1
2010 Han G, Tar M, Kuppam DSR, Friedman A, Melman A, Friedman J, Davies KP. Nanoparticles as a novel delivery vehicle for therapeutics targeting erectile dysfunction Journal of Sexual Medicine. 7: 224-233. PMID 19765204 DOI: 10.1111/j.1743-6109.2009.01507.x  1
2009 Guo F, Friedman JM. Osmolyte-induced perturbations of hydrogen bonding between hydration layer waters: correlation with protein conformational changes. The Journal of Physical Chemistry. B. 113: 16632-42. PMID 19961206 DOI: 10.1021/jp9072284  1
2009 Han G, Martinez LR, Mihu MR, Friedman AJ, Friedman JM, Nosanchuk JD. Nitric oxide releasing nanoparticles are therapeutic for Staphylococcus aureus abscesses in a murine model of infection. Plos One. 4: e7804. PMID 19915659 DOI: 10.1371/Journal.Pone.0007804  1
2009 Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, et al. Nitrate and nitrite in biology, nutrition and therapeutics. Nature Chemical Biology. 5: 865-9. PMID 19915529 DOI: 10.1038/Nchembio.260  1
2009 Shum JW, Lee AW, Lustman K, Friedman JM. Cavernous sinus thrombosis secondary to fracture of posterior maxillary sinus wall. Case report. The New York State Dental Journal. 75: 41-4. PMID 19882841  0.01
2009 Alon T, Zhou L, Pérez CA, Garfield AS, Friedman JM, Heisler LK. Transgenic mice expressing green fluorescent protein under the control of the corticotropin-releasing hormone promoter. Endocrinology. 150: 5626-32. PMID 19854866 DOI: 10.1210/En.2009-0881  1
2009 Portnof JE, Friedman JM, Reich R, Freedman PD, Behrman DA. Oral ectomesenchymal chondromyxoid tumor: case report and literature review. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 108: e20-4. PMID 19716722 DOI: 10.1016/j.tripleo.2009.05.040  1
2009 Tucker T, Marra M, Friedman JM. Massively parallel sequencing: the next big thing in genetic medicine. American Journal of Human Genetics. 85: 142-54. PMID 19679224 DOI: 10.1016/J.Ajhg.2009.06.022  1
2009 Friedman A, Friedman J. New biomaterials for the sustained release of nitric oxide: Past, present and future Expert Opinion On Drug Delivery. 6: 1113-1122. PMID 19663720 DOI: 10.1517/17425240903196743  1
2009 Navati MS, Friedman JM. Reactivity of glass-embedded met hemoglobin derivatives toward external NO: implications for nitrite-mediated production of bioactive NO. Journal of the American Chemical Society. 131: 12273-9. PMID 19663497 DOI: 10.1021/ja903364h  1
2009 Ceccarini G, Flavell RR, Butelman ER, Synan M, Willnow TE, Bar-Dagan M, Goldsmith SJ, Kreek MJ, Kothari P, Vallabhajosula S, Muir TW, Friedman JM. PET imaging of leptin biodistribution and metabolism in rodents and primates. Cell Metabolism. 10: 148-59. PMID 19656493 DOI: 10.1016/J.Cmet.2009.07.001  1
2009 Guo F, Friedman JM. Charge density-dependent modifications of hydration shell waters by Hofmeister ions. Journal of the American Chemical Society. 131: 11010-8. PMID 19603752 DOI: 10.1021/ja902240j  1
2009 Martinez LR, Han G, Chacko M, Mihu MR, Jacobson M, Gialanella P, Friedman AJ, Nosanchuk JD, Friedman JM. Antimicrobial and healing efficacy of sustained release nitric oxide nanoparticles against Staphylococcus aureus skin infection. The Journal of Investigative Dermatology. 129: 2463-9. PMID 19387479 DOI: 10.1038/Jid.2009.95  1
2009 Giordano D, Boechi L, Vergara A, Martí MA, Samuni U, Dantsker D, Grassi L, Estrin DA, Friedman JM, Mazzarella L, di Prisco G, Verde C. The hemoglobins of the sub-Antarctic fish Cottoperca gobio, a phyletically basal species--oxygen-binding equilibria, kinetics and molecular dynamics. The Febs Journal. 276: 2266-77. PMID 19292863 DOI: 10.1111/J.1742-4658.2009.06954.X  1
2008 Rodeheffer MS, Birsoy K, Friedman JM. Identification of white adipocyte progenitor cells in vivo. Cell. 135: 240-9. PMID 18835024 DOI: 10.1016/J.Cell.2008.09.036  1
2008 Birsoy K, Soukas A, Torrens J, Ceccarini G, Montez J, Maffei M, Cohen P, Fayzikhodjaeva G, Viale A, Socci ND, Friedman JM. Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach. Proceedings of the National Academy of Sciences of the United States of America. 105: 12985-90. PMID 18753616 DOI: 10.1073/Pnas.0805621105  1
2008 Ouellet YH, Daigle R, Lagüe P, Dantsker D, Milani M, Bolognesi M, Friedman JM, Guertin M. Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water. The Journal of Biological Chemistry. 283: 27270-8. PMID 18676995 DOI: 10.1074/Jbc.M804215200  1
2008 Flavell RR, Kothari P, Bar-Dagan M, Synan M, Vallabhajosula S, Friedman JM, Muir TW, Ceccarini G. Site-specific (18)F-labeling of the protein hormone leptin using a general two-step ligation procedure. Journal of the American Chemical Society. 130: 9106-12. PMID 18570424 DOI: 10.1021/Ja801666Z  1
2008 Friedman AJ, Han G, Navati MS, Chacko M, Gunther L, Alfieri A, Friedman JM. Sustained release nitric oxide releasing nanoparticles: characterization of a novel delivery platform based on nitrite containing hydrogel/glass composites. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 19: 12-20. PMID 18457680 DOI: 10.1016/j.niox.2008.04.003  1
2007 Samuni U, Roche CJ, Dantsker D, Friedman JM. Conformational dependence of hemoglobin reactivity under high viscosity conditions: the role of solvent slaved dynamics. Journal of the American Chemical Society. 129: 12756-64. PMID 17910446 DOI: 10.1021/Ja072342B  1
2007 Samuni U, Dantsker D, Roche CJ, Friedman JM. Ligand recombination and a hierarchy of solvent slaved dynamics: the origin of kinetic phases in hemeproteins. Gene. 398: 234-48. PMID 17570619 DOI: 10.1016/J.Gene.2007.04.032  1
2007 Nacharaju P, Friedman JM, Prabhakaran M, Acharya SA, Manjula BN. Combining the influence of two low O2 affinity-inducing chemical modifications of the central cavity of hemoglobin. Biochemistry. 46: 4554-64. PMID 17381072 DOI: 10.1021/bi0621462  1
2007 Cheung KJ, Tzameli I, Pissios P, Rovira I, Gavrilova O, Ohtsubo T, Chen Z, Finkel T, Flier JS, Friedman JM. Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity. Cell Metabolism. 5: 115-28. PMID 17276354 DOI: 10.1016/J.Cmet.2007.01.005  1
2006 Roche CJ, Guo F, Friedman JM. Molecular level probing of preferential hydration and its modulation by osmolytes through the use of pyranine complexed to hemoglobin. The Journal of Biological Chemistry. 281: 38757-68. PMID 17057250 DOI: 10.1074/jbc.M608835200  1
2006 Navati MS, Friedman JM. Sugar-derived glasses support thermal and photo-initiated electron transfer processes over macroscopic distances. The Journal of Biological Chemistry. 281: 36021-8. PMID 17005567 DOI: 10.1074/jbc.M606866200  1
2006 Roche CJ, Dantsker D, Samuni U, Friedman JM. Nitrite reductase activity of sol-gel-encapsulated deoxyhemoglobin. Influence of quaternary and tertiary structure. The Journal of Biological Chemistry. 281: 36874-82. PMID 16984908 DOI: 10.1074/Jbc.M603914200  1
2006 Samuni U, Roche CJ, Dantsker D, Juszczak LJ, Friedman JM. Modulation of reactivity and conformation within the T-quaternary state of human hemoglobin: the combined use of mutagenesis and sol-gel encapsulation. Biochemistry. 45: 2820-35. PMID 16503637 DOI: 10.1021/Bi050010I  1
2006 Das TK, Dewilde S, Friedman JM, Moens L, Rousseau DL. Multiple active site conformers in the carbon monoxide complexes of trematode hemoglobins. The Journal of Biological Chemistry. 281: 11471-9. PMID 16481317 DOI: 10.1074/Jbc.M512054200  1
2006 Maliga Z, Xing J, Cheung H, Juszczak LJ, Friedman JM, Rosenfeld SS. A pathway of structural changes produced by monastrol binding to Eg5. The Journal of Biological Chemistry. 281: 7977-82. PMID 16434397 DOI: 10.1074/Jbc.M511955200  1
2006 Alon T, Friedman JM. Late-onset leanness in mice with targeted ablation of melanin concentrating hormone neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 389-97. PMID 16407534 DOI: 10.1523/Jneurosci.1203-05.2006  1
2005 Sternson SM, Shepherd GM, Friedman JM. Topographic mapping of VMH --> arcuate nucleus microcircuits and their reorganization by fasting. Nature Neuroscience. 8: 1356-63. PMID 16172601 DOI: 10.1038/Nn1550  1
2005 Dantsker D, Roche C, Samuni U, Blouin G, Olson JS, Friedman JM. The position 68(E11) side chain in myoglobin regulates ligand capture, bond formation with heme iron, and internal movement into the xenon cavities. The Journal of Biological Chemistry. 280: 38740-55. PMID 16155005 DOI: 10.1074/Jbc.M506333200  1
2005 Acharya SA, Friedman JM, Manjula BN, Intaglietta M, Tsai AG, Winslow RM, Malavalli A, Vandegriff K, Smith PK. Enhanced molecular volume of conservatively pegylated Hb: (SP-PEG5K)6-HbA is non-hypertensive. Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 33: 239-55. PMID 16152690 DOI: 10.1081/Bio-200066365  1
2005 Manjula BN, Tsai AG, Intaglietta M, Tsai CH, Ho C, Smith PK, Perumalsamy K, Kanika ND, Friedman JM, Acharya SA. Conjugation of multiple copies of polyethylene glycol to hemoglobin facilitated through thiolation: influence on hemoglobin structure and function. The Protein Journal. 24: 133-46. PMID 16096719 DOI: 10.1007/S10930-005-7837-2  1
2005 Chen Z, Torrens JI, Anand A, Spiegelman BM, Friedman JM. Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms. Cell Metabolism. 1: 93-106. PMID 16054051 DOI: 10.1016/J.Cmet.2004.12.009  1
2005 Samuni U, Friedman JM. Proteins in motion: resonance Raman spectroscopy as a probe of functional intermediates. Methods in Molecular Biology (Clifton, N.J.). 305: 287-300. PMID 15940003 DOI: 10.1385/1-59259-912-5:287  1
2005 Dantsker D, Samuni U, Friedman JM, Agmon N. A hierarchy of functionally important relaxations within myoglobin based on solvent effects, mutations and kinetic model. Biochimica Et Biophysica Acta. 1749: 234-51. PMID 15914102 DOI: 10.1016/J.Bbapap.2005.04.002  1
2005 Kavanaugh JS, Rogers PH, Arnone A, Hui HL, Wierzba A, DeYoung A, Kwiatkowski LD, Noble RW, Juszczak LJ, Peterson ES, Friedman JM. Intersubunit interactions associated with Tyr42 alpha stabilize the quaternary-T tetramer but are not major quaternary constraints in deoxyhemoglobin. Biochemistry. 44: 3806-20. PMID 15751957 DOI: 10.1021/Bi0484670  1
2005 Cohen P, Yang G, Yu X, Soukas AA, Wolfish CS, Friedman JM, Li C. Induction of leptin receptor expression in the liver by leptin and food deprivation. The Journal of Biological Chemistry. 280: 10034-9. PMID 15644325 DOI: 10.1074/Jbc.M413684200  1
2005 Milani M, Pesce A, Nardini M, Ouellet H, Ouellet Y, Dewilde S, Bocedi A, Ascenzi P, Guertin M, Moens L, Friedman JM, Wittenberg JB, Bolognesi M. Structural bases for heme binding and diatomic ligand recognition in truncated hemoglobins. Journal of Inorganic Biochemistry. 99: 97-109. PMID 15598494 DOI: 10.1016/J.Jinorgbio.2004.10.035  1
2005 Juszczak L, Samuni U, Friedman JM. Conformational and functional significance of the α140 side-chain in HbA: A UV and visible resonance Raman study of three α140 mutants Journal of Raman Spectroscopy. 36: 350-358. DOI: 10.1002/Jrs.1322  1
2004 Samuni U, Dantsker D, Juszczak LJ, Bettati S, Ronda L, Mozzarelli A, Friedman JM. Spectroscopic and functional characterization of T state hemoglobin conformations encapsulated in silica gels. Biochemistry. 43: 13674-82. PMID 15504030 DOI: 10.1021/Bi048531D  1
2004 Tsuneshige A, Kanaori K, Samuni U, Danstker D, Friedman JM, Neya S, Giangiacomo L, Yonetani T. Semihemoglobins, high oxygen affinity dimeric forms of human hemoglobin respond efficiently to allosteric effectors without forming tetramers. The Journal of Biological Chemistry. 279: 48959-67. PMID 15361521 DOI: 10.1074/Jbc.M405909200  1
2004 Cohen P, Friedman JM. Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1). The Journal of Nutrition. 134: 2455S-2463S. PMID 15333742 DOI: 10.1093/Jn/134.9.2455S  1
2004 Dantsker D, Samuni U, Ouellet Y, Wittenberg BA, Wittenberg JB, Milani M, Bolognesi M, Guertin M, Friedman JM. Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 279: 38844-53. PMID 15234986 DOI: 10.1074/Jbc.M401513200  1
2004 Manjula BN, Tsai AG, Intaglietta M, Tsai CH, Ho C, Malavalli A, Vandegriff KD, Winslow RM, Smith PK, Perumalsamy K, Devi Kanika N, Friedman JM, Acharya SA. WITHDRAWN: PEGylated hemoglobin: Role of surface configuration of PEG for the modulation of hemoglobin vasoactivity. The Journal of Biological Chemistry. PMID 15194702 DOI: 10.1074/jbc.M403468200  1
2004 Friedman JM. Modern science versus the stigma of obesity. Nature Medicine. 10: 563-9. PMID 15170194 DOI: 10.1038/Nm0604-563  1
2004 Peterson ES, Shinder R, Khan I, Juczszak L, Wang J, Manjula B, Acharya SA, Bonaventura C, Friedman JM. Domain-specific effector interactions within the central cavity of human adult hemoglobin in solution and in porous sol-gel matrices: evidence for long-range communication pathways. Biochemistry. 43: 4832-43. PMID 15096052 DOI: 10.1021/Bi035481O  1
2004 Pinto S, Roseberry AG, Liu H, Diano S, Shanabrough M, Cai X, Friedman JM, Horvath TL. Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science (New York, N.Y.). 304: 110-5. PMID 15064421 DOI: 10.1126/Science.1089459  1
2004 Milani M, Pesce A, Ouellet Y, Dewilde S, Friedman J, Ascenzi P, Guertin M, Bolognesi M. Heme-ligand tunneling in group I truncated hemoglobins Journal of Biological Chemistry. 279: 21520-21525. PMID 15016811 DOI: 10.1074/Jbc.M401320200  1
2004 Roseberry AG, Liu H, Jackson AC, Cai X, Friedman JM. Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice. Neuron. 41: 711-22. PMID 15003171 DOI: 10.1016/S0896-6273(04)00074-1  1
2004 Samuni U, Ouellet Y, Guertin M, Friedman JM, Yeh SR. The absence of proximal strain in the truncated hemoglobins from Mycobacterium tuberculosis. Journal of the American Chemical Society. 126: 2682-3. PMID 14995168 DOI: 10.1021/Ja038093I  1
2004 Asilmaz E, Cohen P, Miyazaki M, Dobrzyn P, Ueki K, Fayzikhodjaeva G, Soukas AA, Kahn CR, Ntambi JM, Socci ND, Friedman JM. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. The Journal of Clinical Investigation. 113: 414-24. PMID 14755338 DOI: 10.1172/Jci19511  1
2004 Das TK, Samuni U, Lin Y, Goldberg DE, Rousseau DL, Friedman JM. Distal heme pocket conformers of carbonmonoxy derivatives of Ascaris hemoglobin: evidence of conformational trapping in porous sol-gel matrices. The Journal of Biological Chemistry. 279: 10433-41. PMID 14688246 DOI: 10.1074/Jbc.M309590200  1
2004 Navati MS, Ray A, Shamir J, Friedman JM. Probing solvation-shell hydrogen binding in glassy and sol-gel matrixes through vibronic sideband luminescence spectroscopy Journal of Physical Chemistry B. 108: 1321-1327.  1
2003 Cohen P, Ntambi JM, Friedman JM. Stearoyl-CoA desaturase-1 and the metabolic syndrome. Current Drug Targets. Immune, Endocrine and Metabolic Disorders. 3: 271-80. PMID 14683458 DOI: 10.2174/1568008033340117  1
2003 Liedtke W, Tobin DM, Bargmann CI, Friedman JM. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 100: 14531-6. PMID 14581619 DOI: 10.1073/Pnas.2235619100  1
2003 Liedtke W, Friedman JM. Abnormal osmotic regulation in trpv4-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 13698-703. PMID 14581612 DOI: 10.1073/Pnas.1735416100  1
2003 Acharya SA, Malavalli A, Peterson E, Sun PD, Ho C, Prabhakaran M, Arnone A, Manjula BN, Friedman JM. Probing the conformation of hemoglobin presbyterian in the R-state. Journal of Protein Chemistry. 22: 221-30. PMID 12962322 DOI: 10.1023/A:1025080801951  1
2003 Ishii M, Fei H, Friedman JM. Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity. Proceedings of the National Academy of Sciences of the United States of America. 100: 10540-5. PMID 12925742 DOI: 10.1073/Pnas.1334189100  1
2003 Liu H, Kishi T, Roseberry AG, Cai X, Lee CE, Montez JM, Friedman JM, Elmquist JK. Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7143-54. PMID 12904474 DOI: 10.1523/Jneurosci.23-18-07143.2003  1
2003 Samuni U, Juszczak L, Dantsker D, Khan I, Friedman AJ, Pérez-González-de-Apodaca J, Bruno S, Hui HL, Colby JE, Karasik E, Kwiatkowski LD, Mozzarelli A, Noble R, Friedman JM. Functional and spectroscopic characterization of half-liganded iron-zinc hybrid hemoglobin: evidence for conformational plasticity within the T state. Biochemistry. 42: 8272-88. PMID 12846576 DOI: 10.1021/Bi020648J  1
2003 Ouellet H, Juszczak L, Dantsker D, Samuni U, Ouellet YH, Savard PY, Wittenberg JB, Wittenberg BA, Friedman JM, Guertin M. Reactions of Mycobacterium tuberculosis truncated hemoglobin O with ligands reveal a novel ligand-inclusive hydrogen bond network. Biochemistry. 42: 5764-74. PMID 12741834 DOI: 10.1021/Bi0270337  1
2003 Samuni U, Dantsker D, Ray A, Wittenberg JB, Wittenberg BA, Dewilde S, Moens L, Ouellet Y, Guertin M, Friedman JM. Kinetic modulation in carbonmonoxy derivatives of truncated hemoglobins: the role of distal heme pocket residues and extended apolar tunnel. The Journal of Biological Chemistry. 278: 27241-50. PMID 12736253 DOI: 10.1074/Jbc.M212634200  1
2003 Manjula BN, Tsai A, Upadhya R, Perumalsamy K, Smith PK, Malavalli A, Vandegriff K, Winslow RM, Intaglietta M, Prabhakaran M, Friedman JM, Acharya AS. Site-specific PEGylation of hemoglobin at Cys-93(beta): correlation between the colligative properties of the PEGylated protein and the length of the conjugated PEG chain. Bioconjugate Chemistry. 14: 464-72. PMID 12643758 DOI: 10.1021/Bc0200733  1
2003 Juszczak LJ, Fablet C, Baudin-Creuza V, Lesecq-Le Gall S, Hirsch RE, Nagel RL, Friedman JM, Pagnier J. Conformational changes in hemoglobin S (betaE6V) imposed by mutation of the beta Glu7-beta Lys132 salt bridge and detected by UV resonance Raman spectroscopy. The Journal of Biological Chemistry. 278: 7257-63. PMID 12488314 DOI: 10.1074/Jbc.M200691200  1
2003 Navati MS, Samuni U, Aisen P, Friedman JM. Binding and release of iron by gel-encapsulated human transferrin: evidence for a conformational search. Proceedings of the National Academy of Sciences of the United States of America. 100: 3832-7. PMID 12486226 DOI: 10.1073/Pnas.262526399  1
2002 Franzen S, Peterson ES, Brown D, Friedman JM, Thomas MR, Boxer SG. Proximal ligand motions in H93G myoglobin. European Journal of Biochemistry / Febs. 269: 4879-86. PMID 12354119 DOI: 10.1046/J.1432-1033.2002.03193.X  1
2002 Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science (New York, N.Y.). 297: 240-3. PMID 12114623 DOI: 10.1126/Science.1071527  1
2002 Ray A, Friedman BA, Friedman JM. Trehalose glass-facilitated thermal reduction of metmyoglobin and methemoglobin. Journal of the American Chemical Society. 124: 7270-1. PMID 12071726 DOI: 10.1021/ja0201348  1
2002 Samuni U, Dantsker D, Khan I, Friedman AJ, Peterson E, Friedman JM. Spectroscopically and kinetically distinct conformational populations of sol-gel-encapsulated carbonmonoxy myoglobin. A comparison with hemoglobin. The Journal of Biological Chemistry. 277: 25783-90. PMID 11976324 DOI: 10.1074/Jbc.M200301200  1
2002 Dantsker D, Samuni U, Friedman AJ, Yang M, Ray A, Friedman JM. Geminate rebinding in trehalose-glass embedded myoglobins reveals residue-specific control of intramolecular trajectories. Journal of Molecular Biology. 315: 239-51. PMID 11779242 DOI: 10.1006/Jmbi.2001.5218  1
2002 Juszczak LJ, Manjula B, Bonaventura C, Acharya SA, Friedman JM. UV resonance Raman study of beta93-modified hemoglobin A: chemical modifier-specific effects and added influences of attached poly(ethylene glycol) chains. Biochemistry. 41: 376-85. PMID 11772037 DOI: 10.1021/Bi011212R  1
2001 Cohen P, Zhao C, Cai X, Montez JM, Rohani SC, Feinstein P, Mombaerts P, Friedman JM. Selective deletion of leptin receptor in neurons leads to obesity. The Journal of Clinical Investigation. 108: 1113-21. PMID 11602618 DOI: 10.1172/Jci13914  1
2001 Soukas A, Socci ND, Saatkamp BD, Novelli S, Friedman JM. Distinct transcriptional profiles of adipogenesis in vivo and in vitro. The Journal of Biological Chemistry. 276: 34167-74. PMID 11445576 DOI: 10.1074/jbc.M104421200  1
2001 Manjula BN, Malavalli A, Prabhakaran M, Friedman JM, Acharya AS. Activation of the low oxygen affinity-inducing potential of the Asn108(β)→Lys mutation of Hb-Presbyterian on intramolecular αα-fumaryl cross-bridging Protein Engineering. 14: 359-366. PMID 11438759  1
2001 Khan I, Dantsker D, Samuni U, Friedman AJ, Bonaventura C, Manjula B, Acharya SA, Friedman JM. Beta 93 modified hemoglobin: kinetic and conformational consequences. Biochemistry. 40: 7581-92. PMID 11412112 DOI: 10.1021/Bi010051O  1
2001 Shmulewitz D, Auerbach SB, Lehner T, Blundell ML, Winick JD, Youngman LD, Skilling V, Heath SC, Ott J, Stoffel M, Breslow JL, Friedman JM. Epidemiology and factor analysis of obesity, type II diabetes, hypertension, and dyslipidemia (syndrome X) on the Island of Kosrae, Federated States of Micronesia. Human Heredity. 51: 8-19. PMID 11096265 DOI: 10.1159/000022953  1
2000 Khan I, Shannon CF, Dantsker D, Friedman AJ, Perez-Gonzalez-de-Apodaca J, Friedman JM. Sol-gel trapping of functional intermediates of hemoglobin: geminate and bimolecular recombination studies. Biochemistry. 39: 16099-109. PMID 11123938 DOI: 10.1021/bi000536x  1
2000 Liedtke W, Choe Y, Martí-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S. Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell. 103: 525-35. PMID 11081638 DOI: 10.1016/S0092-8674(00)00143-4  1
2000 Malavalli A, Manjula BN, Friedman JM, Acharya AS. Perturbation of the intermolecular contact regions (molecular surface) of hemoglobin S by intramolecular low-O2-affinity-inducing central cavity cross-bridges. Journal of Protein Chemistry. 19: 255-67. PMID 11043930 DOI: 10.1023/A:1007039111556  1
2000 Soukas A, Cohen P, Socci ND, Friedman JM. Leptin-specific patterns of gene expression in white adipose tissue. Genes & Development. 14: 963-80. PMID 10783168 DOI: 10.1101/Gad.14.8.963  1
2000 Manjula BN, Malavalli A, Smith PK, Chan NL, Arnone A, Friedman JM, Acharya AS. Cys-93-betabeta-succinimidophenyl polyethylene glycol 2000 hemoglobin A. Intramolecular cross-bridging of hemoglobin outside the central cavity. The Journal of Biological Chemistry. 275: 5527-34. PMID 10681532 DOI: 10.1074/jbc.275.8.5527  1
2000 Das TK, Friedman JM, Kloek AP, Goldberg DE, Rousseau DL. Origin of the anomalous Fe-CO stretching mode in the CO complex of Ascaris hemoglobin. Biochemistry. 39: 837-42. PMID 10651650 DOI: 10.1021/Bi9922087  1
2000 Samuni U, Navati MS, Juszczak LJ, Dantsker D, Yang M, Friedman JM. Unfolding and refolding of Sol - Gel encapsulated carbonmonoxymyoglobin: An orchestrated spectroscopic study of intermediates and kinetics Journal of Physical Chemistry B. 104: 10802-10813. DOI: 10.1021/Jp000802G  1
2000 Malavalli A, Manjula BN, Friedman JM, Seetharama Acharya A. Perturbation of the intermolecular contact regions (Molecular Surface) of Hemoglobin S by intramolecular, low-O2-affinity-inducing central cavity cross-bridges Protein Journal. 19: 255-267.  1
1999 Friedman JM. Leptin and the regulation of body weight. Harvey Lectures. 95: 107-36. PMID 11446107  0.01
1999 Juszczak LJ, Friedman JM. UV resonance raman spectra of ligand binding intermediates of sol-gel encapsulated hemoglobin. The Journal of Biological Chemistry. 274: 30357-60. PMID 10521410 DOI: 10.1074/jbc.274.43.30357  1
1999 Das TK, Khan I, Rousseau DL, Friedman JM. Temperature dependent quaternary state relaxation in sol-gel encapsulated hemoglobin. Biospectroscopy. 5: S64-70. PMID 10512539 DOI: 10.1002/(Sici)1520-6343(1999)5:5+3.0.Co;2-W  1
1999 Gottfried DS, Manjula BN, Malavalli A, Acharya AS, Friedman JM. Probing the diphosphoglycerate binding pocket of HbA and HbPresbyterian (β108Asn → Lys) Biochemistry. 38: 11307-11315. PMID 10471280 DOI: 10.1021/bi9827464  1
1999 Hirsch RE, Juszczak LJ, Fataliev NA, Friedman JM, Nagel RL. Solution-active structural alterations in liganded hemoglobins C (beta6 Glu --> Lys) and S (beta6 Glu --> Val). The Journal of Biological Chemistry. 274: 13777-82. PMID 10318781 DOI: 10.1074/Jbc.274.20.13777  1
1999 Huang J, Juszczak LJ, Peterson ES, Shannon CF, Yang M, Huang S, Vidugiris GV, Friedman JM. The conformational and dynamic basis for ligand binding reactivity in hemoglobin Ypsilanti (beta 99 asp-->Tyr): origin of the quaternary enhancement effect. Biochemistry. 38: 4514-25. PMID 10194373 DOI: 10.1021/bi982724h  1
1999 Bonaventurat C, Bonaventura J, Shih DTB, Iben ET, Friedman J. Altered ligand rebinding kinetics due to distal-side effects in hemoglobin Chico (Lys(β66) (E10) → Thr) Journal of Biological Chemistry. 274: 8686-8693. PMID 10085107 DOI: 10.1074/Jbc.274.13.8686  1
1999 Gottfried DS, Kagan A, Huffman BM, Friedman JM. Impeded rotation of a protein in a sol-gel matrix Journal of Physical Chemistry B. 103: 2803-2807.  1
1998 Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature. 395: 763-70. PMID 9796811 DOI: 10.1038/27376  1
1998 Falconi M, Desideri A, Cupane A, Leone M, Ciccotti G, Peterson ES, Friedman JM, Gambacurta A, Ascoli F. Structural and dynamic properties of the homodimeric hemoglobin from Scapharca inaequivalvis Thr-72-->Ile mutant: molecular dynamics simulation, low temperature visible absorption spectroscopy, and resonance Raman spectroscopy studies. Biophysical Journal. 75: 2489-503. PMID 9788944 DOI: 10.1016/S0006-3495(98)77693-3  1
1998 Peterson ES, Friedman JM, Chien EY, Sligar SG. Functional implications of the proximal hydrogen-bonding network in myoglobin: a resonance Raman and kinetic study of Leu89, Ser92, His97, and F-helix swap mutants. Biochemistry. 37: 12301-19. PMID 9724545 DOI: 10.1021/Bi980752U  1
1998 Peterson ES, Friedman JM. A possible allosteric communication pathway identified through a resonance Raman study of four beta37 mutants of human hemoglobin A. Biochemistry. 37: 4346-57. PMID 9521755 DOI: 10.1021/bi9708693  1
1998 Fan B, Gupta G, Danziger RS, Friedman JM, Rousseau DL. Resonance Raman characterization of soluble guanylate cyclase expressed from baculovirus. Biochemistry. 37: 1178-84. PMID 9477941 DOI: 10.1021/Bi971934B  1
1998 Das TK, Khan I, Rousseau DL, Friedman JM. Preservation of the native structure in myoglobin at low pH by sol-gel encapsulation Journal of the American Chemical Society. 120: 10268-10269. DOI: 10.1021/Ja982127I  1
1998 Juszczak LJ, Hirsch RE, Nagel RL, Friedman JM. Conformational Differences in CO Derivatives of HbA, HbC (Eβ6K) and HbS (Eβ6V) in the Presence and Absence of Inositol Hexaphosphate Detected Using Ultraviolet Resonance Raman Spectroscopy Journal of Raman Spectroscopy. 29: 963-968. DOI: 10.1002/(Sici)1097-4555(199810/11)29:10/11<963::Aid-Jrs332>3.0.Co;2-4  1
1997 Halaas JL, Friedman JM. Leptin and its receptor. The Journal of Endocrinology. 155: 215-6. PMID 9415051 DOI: 10.1677/Joe.0.1550215  1
1997 Peterson ES, Huang S, Wang J, Miller LM, Vidugiris G, Kloek AP, Goldberg DE, Chance MR, Wittenberg JB, Friedman JM. A comparison of functional and structural consequences of the tyrosine B10 and glutamine E7 motifs in two invertebrate hemoglobins (Ascaris suum and Lucina pectinata). Biochemistry. 36: 13110-21. PMID 9335574 DOI: 10.1021/Bi971156N  1
1997 Kamohara S, Burcelin R, Halaas JL, Friedman JM, Charron MJ. Acute stimulation of glucose metabolism in mice by leptin treatment. Nature. 389: 374-7. PMID 9311777 DOI: 10.1038/38717  1
1997 Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton DA, Friedman JM. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 8878-83. PMID 9238071 DOI: 10.1073/Pnas.94.16.8878  1
1997 Fei H, Okano HJ, Li C, Lee GH, Zhao C, Darnell R, Friedman JM. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proceedings of the National Academy of Sciences of the United States of America. 94: 7001-5. PMID 9192681 DOI: 10.1073/Pnas.94.13.7001  1
1997 Huang S, Peterson ES, Ho C, Friedman JM. Quaternary structure sensitive tyrosine interactions in hemoglobin: a UV resonance Raman study of the double mutant rHb (beta99Asp-->Asn, alpha42Tyr-->Asp). Biochemistry. 36: 6197-206. PMID 9166792 DOI: 10.1021/Bi970018V  1
1997 Boffi A, Chiancone E, Peterson ES, Wang J, Rousseau DL, Friedman JM. Dynamics of cyanide binding to ferrous Scapharca inaequivalvis homodimeric hemoglobin. Biochemistry. 36: 4510-4. PMID 9109659 DOI: 10.1021/Bi961889S  1
1997 Gottfried DS, Juszczak LJ, Fataliev NA, Acharya AS, Hirsch RE, Friedman JM. Probing the hemoglobin central cavity by direct quantification of effector binding using fluorescence lifetime methods. The Journal of Biological Chemistry. 272: 1571-8. PMID 8999830 DOI: 10.1074/Jbc.272.3.1571  1
1997 Simpson MC, Peterson ES, Shannon CF, Eads DD, Friedman JM, Cheatum CM, Ondrias MR. Transient Raman observations of heme electronic and vibrational photodynamics in deoxyhemoglobin Journal of the American Chemical Society. 119: 5110-5117. DOI: 10.1021/Ja961198J  1
1996 Royer WE, Pardanani A, Gibson QH, Peterson ES, Friedman JM. Ordered water molecules as key allosteric mediators in a cooperative dimeric hemoglobin. Proceedings of the National Academy of Sciences of the United States of America. 93: 14526-31. PMID 8962085 DOI: 10.1073/Pnas.93.25.14526  1
1996 Winick JD, Stoffel M, Friedman JM. Identification of microsatellite markers linked to the human leptin receptor gene on chromosome 1. Genomics. 36: 221-2. PMID 8812446 DOI: 10.1006/Geno.1996.0455  1
1996 Huang J, Leone M, Boffi A, Friedman JM, Chiancone E. Near-infrared spectra of Scapharca homodimeric hemoglobin: characterization of the deoxy and photodissociated derivatives. Biophysical Journal. 70: 2924-9. PMID 8744330 DOI: 10.1016/S0006-3495(96)79862-4  1
1996 Huang S, Huang J, Kloek AP, Goldberg DE, Friedman JM. Hydrogen bonding of tyrosine B10 to heme-bound oxygen in Ascaris hemoglobin. Direct evidence from UV resonance Raman spectroscopy. The Journal of Biological Chemistry. 271: 958-62. PMID 8557711 DOI: 10.1074/Jbc.271.2.958  1
1996 Hirsch RE, Lin MJ, Vidugiris GJ, Huang S, Friedman JM, Nagel RL, Vidugirus GV. Conformational changes in oxyhemoglobin C (Glu beta 6-->Lys) detected by spectroscopic probing. The Journal of Biological Chemistry. 271: 372-5. PMID 8550589 DOI: 10.1074/jbc.271.1.372  1
1995 Maffei M, Fei H, Lee GH, Dani C, Leroy P, Zhang Y, Proenca R, Negrel R, Ailhaud G, Friedman JM. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Proceedings of the National Academy of Sciences of the United States of America. 92: 6957-60. PMID 7624352 DOI: 10.1073/Pnas.92.15.6957  1
1994 Hirsch RE, Vidugiris GJ, Friedman JM, Harrington JP. Alteration of tryptophan fluorescence properties upon dissociation of Lumbricus terrestris hemoglobin. Biochimica Et Biophysica Acta. 1205: 248-51. PMID 8155704 DOI: 10.1016/0167-4838(94)90240-2  1
1994 Friedman JM. Time-resolved resonance Raman spectroscopy as probe of structure, dynamics, and reactivity in hemoglobin. Methods in Enzymology. 232: 205-31. PMID 8057861  0.01
1994 Wang J, Smerdon SJ, Jäger J, Kohlstaedt LA, Rice PA, Friedman JM, Steitz TA. Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer. Proceedings of the National Academy of Sciences of the United States of America. 91: 7242-6. PMID 7518928 DOI: 10.1073/Pnas.91.15.7242  1
1994 Smerdon SJ, Jäger J, Wang J, Kohlstaedt LA, Chirino AJ, Friedman JM, Rice PA, Steitz TA. Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences of the United States of America. 91: 3911-5. PMID 7513427 DOI: 10.1073/Pnas.91.9.3911  1
1993 Rousseau DL, Song S, Friedman JM, Boffi A, Chiancone E. Heme-heme interactions in a homodimeric cooperative hemoglobin. Evidence from transient Raman scattering. The Journal of Biological Chemistry. 268: 5719-23. PMID 8449934  1
1993 Schneebeck MC, Vigil LE, Friedman JM, Chavez MD, Ondrias MR. Heme-CO religation in photolyzed hemoglobin: a time-resolved Raman study of the Fe-CO stretching mode. Biochemistry. 32: 1318-23. PMID 8448140 DOI: 10.1021/Bi00056A017  1
1993 Leibel RL, Bahary N, Friedman JM. Strategies for the molecular genetic analysis of obesity in humans. Critical Reviews in Food Science and Nutrition. 33: 351-8. PMID 8357496 DOI: 10.1080/10408399309527632  1
1993 Beese LS, Friedman JM, Steitz TA. Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. Biochemistry. 32: 14095-101. PMID 8260491 DOI: 10.1021/Bi00214A004  1
1993 Vidugiris GJ, Harrington JP, Friedman JM, Hirsch RE. Absence of ligand binding-induced tertiary changes in the multimeric earthworm Lumbricus terrestris hemoglobin. A resonance Raman study. The Journal of Biological Chemistry. 268: 26190-2. PMID 8253738  1
1993 Bahary N, McGraw DE, Shilling R, Friedman JM. Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones. Genomics. 16: 113-22. PMID 8098006 DOI: 10.1006/Geno.1993.1148  1
1993 Bahary N, Siegel DA, Walsh J, Zhang Y, Leopold L, Leibel R, Proenca R, Friedman JM. Microdissection of proximal mouse chromosome 6: identification of RFLPs tightly linked to the ob mutation. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 511-5. PMID 7906968 DOI: 10.1007/Bf00364786  1
1993 Steitz TA, Smerdon S, Jäger J, Wang J, Kohlstaedt LA, Friedman JM, Beese LS, Rice PA. Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I. Cold Spring Harbor Symposia On Quantitative Biology. 58: 495-504. PMID 7525146 DOI: 10.1101/Sqb.1993.058.01.056  1
1992 Kohlstaedt LA, Wang J, Friedman JM, Rice PA, Steitz TA. Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science (New York, N.Y.). 256: 1783-90. PMID 1377403 DOI: 10.1126/Science.1377403  1
1991 Iben IE, Cowen BR, Sanches R, Friedman JM. Carboxy Mb at pH 3. Time-resolved resonance Raman study at cryogenic temperatures. Biophysical Journal. 59: 908-19. PMID 2065191 DOI: 10.1016/S0006-3495(91)82304-9  0.16
1991 Truett GE, Bahary N, Friedman JM, Leibel RL. Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db). Proceedings of the National Academy of Sciences of the United States of America. 88: 7806-9. PMID 1881916 DOI: 10.1073/Pnas.88.17.7806  1
1991 Bahary N, Zorich G, Pachter JE, Leibel RL, Friedman JM. Molecular genetic linkage maps of mouse chromosomes 4 and 6. Genomics. 11: 33-47. PMID 1684952 DOI: 10.1016/0888-7543(91)90099-Z  1
1990 Chavez MD, Courtney SH, Chance MR, Kiula D, Nocek J, Hoffman BM, Friedman JM, Ondrias MR. Structural and functional significance of inhomogeneous line broadening of band III in hemoglobin and Fe-Mn hybrid hemoglobins. Biochemistry. 29: 4844-52. PMID 2364063 DOI: 10.1021/Bi00472A014  1
1990 Larsen RW, Chavez MD, Ondrias MR, Courtney SH, Friedman JM, Lin MJ, Hirsch RE. Dynamics and reactivity of HbXL99 alpha. A cross-linked hemoglobin derivative. The Journal of Biological Chemistry. 265: 4449-54. PMID 2307673  1
1990 Friedman JM, Campbell BF, Noble RW. A possible new control mechanism suggested by resonance Raman spectra from a deep ocean fish hemoglobin. Biophysical Chemistry. 37: 43-59. PMID 2285802 DOI: 10.1016/0301-4622(90)88006-E  1
1990 Babiss LE, Friedman JM. Regulation of N-myc gene expression: use of an adenovirus vector to demonstrate posttranscriptional control. Molecular and Cellular Biology. 10: 6700-8. PMID 2147226 DOI: 10.1128/Mcb.10.12.6700  0.01
1990 Bahary N, Leibel RL, Joseph L, Friedman JM. Molecular mapping of the mouse db mutation. Proceedings of the National Academy of Sciences of the United States of America. 87: 8642-6. PMID 1978328 DOI: 10.1073/Pnas.87.21.8642  1
1989 Scott TW, Campbell BF, Cone RL, Friedman JM. Line narrowing and site selectivity in tryptophan fluorescence from proteins and glasses: Cryogenic studies of conformational disorder and dynamics Chemical Physics. 131: 63-79. DOI: 10.1016/0301-0104(89)87081-8  1
1988 Findsen EW, Friedman JM, Ondrias MR. Effect of solvent viscosity on the heme-pocket dynamics of photolyzed (carbonmonoxy)hemoglobin. Biochemistry. 27: 8719-24. PMID 3242601 DOI: 10.1021/Bi00424A005  1
1988 Freemont PS, Friedman JM, Beese LS, Sanderson MR, Steitz TA. Cocrystal structure of an editing complex of Klenow fragment with DNA. Proceedings of the National Academy of Sciences of the United States of America. 85: 8924-8. PMID 3194400 DOI: 10.1073/Pnas.85.23.8924  1
1988 Derbyshire V, Freemont PS, Sanderson MR, Beese L, Friedman JM, Joyce CM, Steitz TA. Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. Science (New York, N.Y.). 240: 199-201. PMID 2832946 DOI: 10.1126/Science.2832946  1
1987 Carson SD, Wells CA, Findsen EW, Friedman JM, Ondrias MR. Interspecies variations in the transient heme species generated subsequent to CO photolysis from hemoglobins. The Journal of Biological Chemistry. 262: 3044-51. PMID 3818632  1
1987 Campbell BF, Chance MR, Friedman JM. Ligand binding channels reflected in the resonance Raman spectra of cryogenically trapped species of myoglobin. The Journal of Biological Chemistry. 262: 14885-90. PMID 3667612  1
1987 Campbell BF, Chance MR, Friedman JM. Linkage of functional and structural heterogeneity in proteins: dynamic hole burning in carboxymyoglobin. Science (New York, N.Y.). 238: 373-6. PMID 3659921 DOI: 10.1126/SCIENCE.3659921  1
1987 Chance MR, Campbell BF, Hoover R, Friedman JM. Myoglobin recombination at low temperature. Two phases revealed by Fourier transform infrared spectroscopy. The Journal of Biological Chemistry. 262: 6959-61. PMID 3584103  1
1987 Steitz TA, Beese L, Freemont PS, Friedman JM, Sanderson MR. Structural studies of Klenow fragment: an enzyme with two active sites. Cold Spring Harbor Symposia On Quantitative Biology. 52: 465-71. PMID 3331343 DOI: 10.1101/Sqb.1987.052.01.053  1
1986 Findsen EW, Shelnutt JA, Friedman JM, Ondrias MR. Resonance Raman investigation of transient photoinduced ligation changes in nickel octaethyl porphyrin Chemical Physics Letters. 126: 465-471. DOI: 10.1016/S0009-2614(86)80137-3  1
1985 Findsen EW, Friedman JM, Ondrias MR, Simon SR. Picosecond time-resolved resonance Raman studies of hemoglobin: implications for reactivity. Science (New York, N.Y.). 229: 661-5. PMID 4023704 DOI: 10.1126/Science.4023704  1
1985 Friedman JM, Scott TW, Fisanick GJ, Simon SR, Findsen EW, Ondrias MR, Macdonald VW. Localized control of ligand binding in hemoglobin: effect of tertiary structure on picosecond geminate recombination. Science (New York, N.Y.). 229: 187-90. PMID 4012316 DOI: 10.1126/Science.4012316  1
1985 Friedman JM. Structure, dynamics, and reactivity in hemoglobin. Science (New York, N.Y.). 228: 1273-80. PMID 4001941  0.01
1984 Ondrias MR, Scott TW, Friedman JM, Macdonald VW. A resonance Raman study of the temperature dependence of ligand photolysis and recombination in hemoglobins Chemical Physics Letters. 112: 351-355. DOI: 10.1016/0009-2614(84)85756-5  1
1983 Friedman JM, Scott TW, Stepnoski RA, Ikeda-Saito M, Yonetani T. The iron-proximal histidine linkage and protein control of oxygen binding in hemoglobin. A transient Raman study. The Journal of Biological Chemistry. 258: 10564-72. PMID 6885793  1
1983 Scott TW, Friedman JM, Ikeda-Saito M, Yonetani T. Subunit heterogeneity in the structure and dynamics of hemoglobin. A transient Raman study. Febs Letters. 158: 68-72. PMID 6862033 DOI: 10.1016/0014-5793(83)80678-4  1
1983 Ondrias MR, Friedman JM, Rousseau DL. Metastable species of hemoglobin: room temperature transients and cryogenically trapped intermediates. Science (New York, N.Y.). 220: 615-7. PMID 6836305  1
1982 Friedman JM, Rousseau DL, Ondrias MR, Stepnoski RA. Transient Raman study of hemoglobin: structural dependence of the iron-histidine linkage. Science (New York, N.Y.). 218: 1244-6. PMID 7146910  1
1982 Friedman JM, Stepnoski RA, Stavola M, Ondrias MR, Cone RL. Ligation and quaternary structure induced changes in the heme pocket of hemoglobin: a transient resonance Raman study. Biochemistry. 21: 2022-8. PMID 7093226  1
1982 Ashkin A, Smith PW, Dziedzic JM, Siekhaus WJ, Lowdermilk WH, Swain JE, Cone RL, Ender DA, Otteson MS, Fisher PL, Friedman JM, Guggenheim HJ, Peihui L, Zhongmin G, Weiqing Z, et al. Nonlinear optical processes I Applied Physics B Photophysics and Laser Chemistry. 28: 142-149. DOI: 10.1007/Bf00697839  1
1981 Sadowsky D, Rosenberg RD, Kaufman J, Levine BC, Friedman JM. Central hemangioma of the mandible. Literature review, case report, and discussion. Oral Surgery, Oral Medicine, and Oral Pathology. 52: 471-7. PMID 6946373 DOI: 10.1016/0030-4220(81)90356-X  0.01
1980 Rousseau DL, Shelnutt JA, Friedman JM, Henry ER, Simon SR. Charge transfer stabilization of hemoglobin structures. Biophysical Journal. 32: 83-5. PMID 19431414 DOI: 10.1016/S0006-3495(80)84920-4  1
1980 Friedman JM. Studies of dynamical processes in photodissociated carboxyhemeproteins using time resolved resonance Raman scattering. Biophysical Journal. 32: 636-8. PMID 19431404  0.01
1980 Friedman JM, Lyons KB. Transient Raman study of CO-haemoprotein photolysis: origin of the quantum yield. Nature. 284: 570-2. PMID 7366727  1
1980 Friedman JM, Bondybey VE, Rousseau DL. Br2 in an ar matrix: an example of complete damping of the resonance raman scattering amplitude in the discrete resonance limit Chemical Physics Letters. 70: 499-503. DOI: 10.1016/0009-2614(80)80112-6  1
1979 Shelnutt JA, Rousseau DL, Friedman JM, Simon SR. Protein-heme interaction in hemoglobin: evidence from Raman difference spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 76: 4409-13. PMID 291973 DOI: 10.1073/Pnas.76.9.4409  1
1979 Friedman JM, Rousseau DL, Navon G, Rosenfeld S, Glynn P, Lyons KB. Ruthenium red as a resonance Raman probe of Ca2+ binding sites in biological materials. Archives of Biochemistry and Biophysics. 193: 14-21. PMID 222215 DOI: 10.1016/0003-9861(79)90002-X  1
1979 Friedman JM, Rousseau DL, Shen C, Chiang CC, Duesler EN, Paul IC. Lasalocid crystallized from methanol: Spectroscopic and x-ray structural evidence for two structures Journal of the Chemical Society, Perkin Transactions 2. 835-838. DOI: 10.1039/P29790000835  1
1979 Friedman JM, Rousseau DL, Shen C. The effect of deuteration on the carboxyl stretching frequencies of a salicylic acid derivative Spectrochimica Acta Part a: Molecular Spectroscopy. 35: 989-991. DOI: 10.1016/0584-8539(79)80024-0  1
1978 Lyons KB, Friedman JM, Fleury PA. Nanosecond transient Raman spectra of photolysed carboxyhaemoglobin. Nature. 275: 565-6. PMID 692736  1
1978 Friedman JM, Rousseau DL. Simultaneous observation of coherent and incoherent resonant re-emission in the condensed phase Chemical Physics Letters. 55: 488-492. DOI: 10.1016/0009-2614(78)84020-2  1
1977 Friedman JM, Rousseau DL, Adar F. Excited state lifetimes in cytochromes measured from Raman scattering data: evidence for iron-porphyrin interactions. Proceedings of the National Academy of Sciences of the United States of America. 74: 2607-11. PMID 197515 DOI: 10.1073/Pnas.74.7.2607  1
1977 Friedman JM, Rousseau DL, Shen C, Paul IC. Infrared evidence for hydrogen bonding in the sodium salts of lasalocid a (X-537A) Journal of the Chemical Society, Chemical Communications. 684-686. DOI: 10.1039/C39770000684  1
1976 Friedman JM, Rousseau DL, Bondybey VE. Origin of resonant Raman excitation profiles red-shifted from optical absorption profiles Physical Review Letters. 37: 1610-1613. DOI: 10.1103/Physrevlett.37.1610  1
1975 Friedman J, Hochstrasser RM. Interference effects in resonance raman spectroscopy Chemical Physics Letters. 32: 414-419. DOI: 10.1016/0009-2614(75)85205-5  1
1974 Friedman JM, Hochstrasser RM. Moderately high resolution fluorecence spectrum of the S1 → S0 transition of azulene Chemical Physics. 6: 145-154. DOI: 10.1016/0301-0104(74)85056-1  1
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