| Year |
Citation |
Score |
| 2021 |
López-Pérez W, Sai K, Sakamachi Y, Parsons C, Kathariou S, Ninomiya-Tsuji J. TAK1 inhibition elicits mitochondrial ROS to block intracellular bacterial colonization. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34161265 DOI: 10.1073/pnas.2023647118 |
0.366 |
|
| 2019 |
Sai K, Parsons C, House JS, Kathariou S, Ninomiya-Tsuji J. Necroptosis mediators RIPK3 and MLKL suppress intracellular replication independently of host cell killing. The Journal of Cell Biology. PMID 30975711 DOI: 10.1083/Jcb.201810014 |
0.416 |
|
| 2019 |
Sung Hsieh HH, Agarwal S, Cholok DJ, Loder SJ, Kaneko K, Huber A, Chung MT, Ranganathan K, Habbouche J, Li J, Butts J, Reimer J, Kaura A, Drake J, Breuler C, ... ... Ninomiya-Tsuji J, et al. Coordinating Tissue Regeneration through TGF-β Activated Kinase 1 (TAK1) In-activation and Re-activation. Stem Cells (Dayton, Ohio). PMID 30786091 DOI: 10.1002/Stem.2991 |
0.354 |
|
| 2018 |
Liu X, Hayano S, Pan H, Inagaki M, Ninomiya-Tsuji J, Sun H, Mishina Y. Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death. Genesis (New York, N.Y. : 2000). PMID 29411501 DOI: 10.1002/Dvg.23093 |
0.341 |
|
| 2017 |
Mihaly SR, Sakamachi Y, Ninomiya-Tsuji J, Morioka S. Erratum: Noncanonical cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1. Scientific Reports. 7: 10695. PMID 28878387 DOI: 10.1038/s41598-017-09609-z |
0.745 |
|
| 2017 |
Mihaly SR, Sakamachi Y, Ninomiya-Tsuji J, Morioka S. Noncanocial cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1. Scientific Reports. 7: 2918. PMID 28592892 DOI: 10.1038/S41598-017-03112-1 |
0.755 |
|
| 2017 |
Sakamachi Y, Morioka S, Mihaly SR, Takaesu G, Foley JF, Fessler MB, Ninomiya-Tsuji J. TAK1 regulates resident macrophages by protecting lysosomal integrity. Cell Death & Disease. 8: e2598. PMID 28182011 DOI: 10.1038/Cddis.2017.23 |
0.75 |
|
| 2016 |
Hashimoto K, Simmons AN, Kajino-Sakamoto R, Tsuji Y, Ninomiya-Tsuji J. TAK1 regulates the Nrf2 antioxidant system through modulating p62/ SQSTM1. Antioxidants & Redox Signaling. PMID 27245349 DOI: 10.1089/Ars.2016.6663 |
0.396 |
|
| 2016 |
Simmons AN, Kajino-Sakamoto R, Ninomiya-Tsuji J. TAK1 regulates Paneth cell integrity partly through blocking necroptosis. Cell Death & Disease. 7: e2196. PMID 27077812 DOI: 10.1038/Cddis.2016.98 |
0.497 |
|
| 2016 |
Sai K, Morioka S, Takaesu G, Muthusamy N, Ghashghaei HT, Hanafusa H, Matsumoto K, Ninomiya-Tsuji J. TAK1 determines susceptibility to endoplasmic reticulum stress and hypothalamic leptin resistance. Journal of Cell Science. PMID 26985063 DOI: 10.1242/Jcs.180505 |
0.346 |
|
| 2016 |
Morioka S, Sai K, Omori E, Ikeda Y, Matsumoto K, Ninomiya-Tsuji J. TAK1 regulates hepatic lipid homeostasis through SREBP Oncogene. DOI: 10.1038/Onc.2015.453 |
0.335 |
|
| 2015 |
Lane J, Yumoto K, Azhar M, Ninomiya-Tsuji J, Inagaki M, Hu Y, Deng CX, Kim J, Mishina Y, Kaartinen V. Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development. Developmental Biology. 398: 231-41. PMID 25523394 DOI: 10.1016/J.Ydbio.2014.12.006 |
0.361 |
|
| 2014 |
Mihaly SR, Ninomiya-Tsuji J, Morioka S. TAK1 control of cell death. Cell Death and Differentiation. 21: 1667-76. PMID 25146924 DOI: 10.1038/Cdd.2014.123 |
0.763 |
|
| 2014 |
Mihaly SR, Morioka S, Ninomiya-Tsuji J, Takaesu G. Activated macrophage survival is coordinated by TAK1 binding proteins. Plos One. 9: e94982. PMID 24736749 DOI: 10.1371/Journal.Pone.0094982 |
0.737 |
|
| 2014 |
Morioka S, Broglie P, Omori E, Ikeda Y, Takaesu G, Matsumoto K, Ninomiya-Tsuji J. TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation. The Journal of Cell Biology. 204: 607-23. PMID 24535827 DOI: 10.1083/Jcb.201305070 |
0.583 |
|
| 2014 |
Ikeda Y, Morioka S, Matsumoto K, Ninomiya-Tsuji J. TAK1 binding protein 2 is essential for liver protection from stressors. Plos One. 9: e88037. PMID 24498425 DOI: 10.1371/Journal.Pone.0088037 |
0.36 |
|
| 2013 |
Yumoto K, Thomas PS, Lane J, Matsuzaki K, Inagaki M, Ninomiya-Tsuji J, Scott GJ, Ray MK, Ishii M, Maxson R, Mishina Y, Kaartinen V. TGF-β-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells. The Journal of Biological Chemistry. 288: 13467-80. PMID 23546880 DOI: 10.1074/Jbc.M112.431775 |
0.412 |
|
| 2013 |
Moreno-García ME, Sommer K, Rincon-Arano H, Brault M, Ninomiya-Tsuji J, Matesic LE, Rawlings DJ. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-κB activation. Molecular and Cellular Biology. 33: 1149-63. PMID 23297344 DOI: 10.1128/Mcb.06407-11 |
0.531 |
|
| 2012 |
Takaesu G, Inagaki M, Takubo K, Mishina Y, Hess PR, Dean GA, Yoshimura A, Matsumoto K, Suda T, Ninomiya-Tsuji J. TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms. Plos One. 7: e51073. PMID 23226465 DOI: 10.1371/Journal.Pone.0051073 |
0.482 |
|
| 2012 |
Morioka S, Inagaki M, Komatsu Y, Mishina Y, Matsumoto K, Ninomiya-Tsuji J. TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration. Blood. 120: 3846-57. PMID 22972987 DOI: 10.1182/Blood-2012-03-416198 |
0.462 |
|
| 2012 |
Omori E, Inagaki M, Mishina Y, Matsumoto K, Ninomiya-Tsuji J. Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species. Proceedings of the National Academy of Sciences of the United States of America. 109: 3365-70. PMID 22331902 DOI: 10.1073/Pnas.1116188109 |
0.514 |
|
| 2011 |
Criollo A, Niso-Santano M, Malik SA, Michaud M, Morselli E, Mariño G, Lachkar S, Arkhipenko AV, Harper F, Pierron G, Rain JC, Ninomiya-Tsuji J, Fuentes JM, Lavandero S, Galluzzi L, et al. Inhibition of autophagy by TAB2 and TAB3. The Embo Journal. 30: 4908-20. PMID 22081109 DOI: 10.1038/Emboj.2011.413 |
0.372 |
|
| 2011 |
Omori E, Matsumoto K, Ninomiya-Tsuji J. Non-canonical β-catenin degradation mediates reactive oxygen species-induced epidermal cell death. Oncogene. 30: 3336-44. PMID 21383695 DOI: 10.1038/Onc.2011.49 |
0.444 |
|
| 2010 |
Omori E, Matsumoto K, Zhu S, Smart RC, Ninomiya-Tsuji J. Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cells. Cancer Research. 70: 8417-25. PMID 20959492 DOI: 10.1158/0008-5472.Can-10-1227 |
0.383 |
|
| 2010 |
Kajino-Sakamoto R, Omori E, Nighot PK, Blikslager AT, Matsumoto K, Ninomiya-Tsuji J. TGF-beta-activated kinase 1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium. Journal of Immunology (Baltimore, Md. : 1950). 185: 4729-37. PMID 20855879 DOI: 10.4049/Jimmunol.0903587 |
0.422 |
|
| 2010 |
Sakamoto K, Huang BW, Iwasaki K, Hailemariam K, Ninomiya-Tsuji J, Tsuji Y. Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271. Molecular Biology of the Cell. 21: 2966-74. PMID 20573984 DOI: 10.1091/Mbc.E10-01-0015 |
0.454 |
|
| 2010 |
Broglie P, Matsumoto K, Akira S, Brautigan DL, Ninomiya-Tsuji J. Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway. The Journal of Biological Chemistry. 285: 2333-9. PMID 19955178 DOI: 10.1074/Jbc.M109.090522 |
0.502 |
|
| 2009 |
Morioka S, Omori E, Kajino T, Kajino-Sakamoto R, Matsumoto K, Ninomiya-Tsuji J. TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP. Oncogene. 28: 2257-65. PMID 19421137 DOI: 10.1038/Onc.2009.110 |
0.552 |
|
| 2009 |
Kim JY, Kajino-Sakamoto R, Omori E, Jobin C, Ninomiya-Tsuji J. Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis. Plos One. 4: e4561. PMID 19234607 DOI: 10.1371/Journal.Pone.0004561 |
0.415 |
|
| 2008 |
Inagaki M, Omori E, Kim JY, Komatsu Y, Scott G, Ray MK, Yamada G, Matsumoto K, Mishina Y, Ninomiya-Tsuji J. TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling. The Journal of Biological Chemistry. 283: 33080-6. PMID 18829460 DOI: 10.1074/Jbc.M807574200 |
0.491 |
|
| 2008 |
Inagaki M, Komatsu Y, Scott G, Yamada G, Ray M, Ninomiya-Tsuji J, Mishina Y. Generation of a conditional mutant allele for Tab1 in mouse. Genesis (New York, N.Y. : 2000). 46: 431-9. PMID 18693278 DOI: 10.1002/Dvg.20418 |
0.456 |
|
| 2008 |
Omori E, Morioka S, Matsumoto K, Ninomiya-Tsuji J. TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity. The Journal of Biological Chemistry. 283: 26161-8. PMID 18606807 DOI: 10.1074/Jbc.M804513200 |
0.46 |
|
| 2008 |
Kajino-Sakamoto R, Inagaki M, Lippert E, Akira S, Robine S, Matsumoto K, Jobin C, Ninomiya-Tsuji J. Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis. Journal of Immunology (Baltimore, Md. : 1950). 181: 1143-52. PMID 18606667 DOI: 10.4049/Jimmunol.181.2.1143 |
0.41 |
|
| 2008 |
Prickett TD, Ninomiya-Tsuji J, Broglie P, Muratore-Schroeder TL, Shabanowitz J, Hunt DF, Brautigan DL. TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB. The Journal of Biological Chemistry. 283: 19245-54. PMID 18456659 DOI: 10.1074/Jbc.M800943200 |
0.444 |
|
| 2008 |
Kim JY, Omori E, Matsumoto K, Núñez G, Ninomiya-Tsuji J. TAK1 is a central mediator of NOD2 signaling in epidermal cells. The Journal of Biological Chemistry. 283: 137-44. PMID 17965022 DOI: 10.1074/Jbc.M704746200 |
0.441 |
|
| 2008 |
Kajino-Sakamoto R, Inagaki M, Kim J, Robine S, Matsumoto K, Jobin C, Ninomiya-Tsuji J. 203 TAK1 Is Essential for Intestinal Epithelial Cell Survival and Regulates Intestinal Integrity Gastroenterology. 134: A-35-A-36. DOI: 10.1016/S0016-5085(08)60172-9 |
0.324 |
|
| 2007 |
HuangFu WC, Matsumoto K, Ninomiya-Tsuji J. Osmotic stress blocks NF-kappaB-dependent inflammatory responses by inhibiting ubiquitination of IkappaB. Febs Letters. 581: 5549-54. PMID 17997988 DOI: 10.1016/J.Febslet.2007.11.002 |
0.401 |
|
| 2007 |
Kajino T, Omori E, Ishii S, Matsumoto K, Ninomiya-Tsuji J. TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation. The Journal of Biological Chemistry. 282: 9475-81. PMID 17276978 DOI: 10.1074/Jbc.M700875200 |
0.319 |
|
| 2006 |
Kajino T, Ren H, Iemura S, Natsume T, Stefansson B, Brautigan DL, Matsumoto K, Ninomiya-Tsuji J. Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway. The Journal of Biological Chemistry. 281: 39891-6. PMID 17079228 DOI: 10.1074/Jbc.M608155200 |
0.482 |
|
| 2006 |
Sato S, Sanjo H, Tsujimura T, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Takeuchi O, Akira S. TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells. International Immunology. 18: 1405-11. PMID 16940043 DOI: 10.1093/Intimm/Dxl082 |
0.451 |
|
| 2006 |
Huangfu WC, Omori E, Akira S, Matsumoto K, Ninomiya-Tsuji J. Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways. The Journal of Biological Chemistry. 281: 28802-10. PMID 16893890 DOI: 10.1074/Jbc.M603627200 |
0.476 |
|
| 2006 |
Omori E, Matsumoto K, Sanjo H, Sato S, Akira S, Smart RC, Ninomiya-Tsuji J. TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. The Journal of Biological Chemistry. 281: 19610-7. PMID 16675448 DOI: 10.1074/Jbc.M603384200 |
0.491 |
|
| 2006 |
Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, Ninomiya-Tsuji J. TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB. The Journal of Biological Chemistry. 281: 7863-72. PMID 16446357 DOI: 10.1074/Jbc.M509834200 |
0.468 |
|
| 2005 |
Sato S, Sanjo H, Takeda K, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Matsumoto K, Takeuchi O, Akira S. Essential function for the kinase TAK1 in innate and adaptive immune responses. Nature Immunology. 6: 1087-95. PMID 16186825 DOI: 10.1038/Ni1255 |
0.437 |
|
| 2005 |
Li J, Miller EJ, Ninomiya-Tsuji J, Russell RR, Young LH. AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart. Circulation Research. 97: 872-9. PMID 16179588 DOI: 10.1161/01.Res.0000187458.77026.10 |
0.401 |
|
| 2005 |
Safwat N, Ninomiya-Tsuji J, Gore AJ, Miller WL. Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression. Endocrinology. 146: 4814-24. PMID 16081641 DOI: 10.1210/En.2005-0457 |
0.453 |
|
| 2005 |
Kishida S, Sanjo H, Akira S, Matsumoto K, Ninomiya-Tsuji J. TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 10: 447-54. PMID 15836773 DOI: 10.1111/J.1365-2443.2005.00852.X |
0.414 |
|
| 2004 |
Akiyama S, Yonezawa T, Kudo TA, Li MG, Wang H, Ito M, Yoshioka K, Ninomiya-Tsuji J, Matsumoto K, Kanamaru R, Tamura S, Kobayashi T. Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells. The Journal of Biological Chemistry. 279: 36616-20. PMID 15218018 DOI: 10.1074/Jbc.M406610200 |
0.469 |
|
| 2004 |
Kanei-Ishii C, Ninomiya-Tsuji J, Tanikawa J, Nomura T, Ishitani T, Kishida S, Kokura K, Kurahashi T, Ichikawa-Iwata E, Kim Y, Matsumoto K, Ishii S. Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK. Genes & Development. 18: 816-29. PMID 15082531 DOI: 10.1101/Gad.1170604 |
0.469 |
|
| 2004 |
Takeda K, Matsuzawa A, Nishitoh H, Tobiume K, Kishida S, Ninomiya-Tsuji J, Matsumoto K, Ichijo H. Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation. Embo Reports. 5: 161-6. PMID 14749717 DOI: 10.1038/sj.embor.7400072 |
0.32 |
|
| 2003 |
Ishitani T, Takaesu G, Ninomiya-Tsuji J, Shibuya H, Gaynor RB, Matsumoto K. Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling. The Embo Journal. 22: 6277-88. PMID 14633987 DOI: 10.1093/Emboj/Cdg605 |
0.382 |
|
| 2003 |
Ono K, Ohtomo T, Ninomiya-Tsuji J, Tsuchiya M. A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta. Biochemical and Biophysical Research Communications. 307: 332-7. PMID 12859960 DOI: 10.1016/S0006-291X(03)01207-5 |
0.346 |
|
| 2003 |
Ninomiya-Tsuji J, Kajino T, Ono K, Ohtomo T, Matsumoto M, Shiina M, Mihara M, Tsuchiya M, Matsumoto K. A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase. The Journal of Biological Chemistry. 278: 18485-90. PMID 12624112 DOI: 10.1074/Jbc.M207453200 |
0.468 |
|
| 2003 |
Li MG, Katsura K, Nomiyama H, Komaki K, Ninomiya-Tsuji J, Matsumoto K, Kobayashi T, Tamura S. Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon). The Journal of Biological Chemistry. 278: 12013-21. PMID 12556533 DOI: 10.1074/Jbc.M211474200 |
0.41 |
|
| 2003 |
Ishitani T, Ninomiya-Tsuji J, Matsumoto K. Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling. Molecular and Cellular Biology. 23: 1379-89. PMID 12556497 DOI: 10.1128/Mcb.23.4.1379-1389.2003 |
0.427 |
|
| 2003 |
Sanjo H, Takeda K, Tsujimura T, Ninomiya-Tsuji J, Matsumoto K, Akira S. TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling. Molecular and Cellular Biology. 23: 1231-8. PMID 12556483 DOI: 10.1128/Mcb.23.4.1231-1238.2003 |
0.459 |
|
| 2003 |
Takaesu G, Surabhi RM, Park KJ, Ninomiya-Tsuji J, Matsumoto K, Gaynor RB. TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. Journal of Molecular Biology. 326: 105-15. PMID 12547194 DOI: 10.1016/S0022-2836(02)01404-3 |
0.478 |
|
| 2003 |
Ishitani T, Kishida S, Hyodo-Miura J, Ueno N, Yasuda J, Waterman M, Shibuya H, Moon RT, Ninomiya-Tsuji J, Matsumoto K. The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling. Molecular and Cellular Biology. 23: 131-9. PMID 12482967 DOI: 10.1128/Mcb.23.1.131-139.2003 |
0.429 |
|
| 2002 |
Komatsu Y, Shibuya H, Takeda N, Ninomiya-Tsuji J, Yasui T, Miyado K, Sekimoto T, Ueno N, Matsumoto K, Yamada G. Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis. Mechanisms of Development. 119: 239-49. PMID 12464436 DOI: 10.1016/S0925-4773(02)00391-X |
0.398 |
|
| 2002 |
Jiang Z, Ninomiya-Tsuji J, Qian Y, Matsumoto K, Li X. Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Molecular and Cellular Biology. 22: 7158-67. PMID 12242293 DOI: 10.1128/Mcb.22.20.7158-7167.2002 |
0.351 |
|
| 2002 |
Mizukami J, Takaesu G, Akatsuka H, Sakurai H, Ninomiya-Tsuji J, Matsumoto K, Sakurai N. Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6. Molecular and Cellular Biology. 22: 992-1000. PMID 11809792 DOI: 10.1128/Mcb.22.4.992-1000.2002 |
0.511 |
|
| 2001 |
Qian Y, Commane M, Ninomiya-Tsuji J, Matsumoto K, Li X. IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B. The Journal of Biological Chemistry. 276: 41661-7. PMID 11518704 DOI: 10.1074/JBC.M102262200 |
0.304 |
|
| 2001 |
Takaesu G, Ninomiya-Tsuji J, Kishida S, Li X, Stark GR, Matsumoto K. Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Molecular and Cellular Biology. 21: 2475-84. PMID 11259596 DOI: 10.1128/Mcb.21.7.2475-2484.2001 |
0.369 |
|
| 2001 |
Holtmann H, Enninga J, Kälble S, Thiefes A, Dörrie A, Broemer M, Winzen R, Wilhelm A, Ninomiya-Tsuji J, Matsumoto K, Resch K, Kracht M. The MAPK Kinase Kinase TAK1 Plays a Central Role in Coupling the Interleukin-1 Receptor to Both Transcriptional and RNA-targeted Mechanisms of Gene Regulation Journal of Biological Chemistry. 276: 3508-3516. PMID 11050078 DOI: 10.1074/Jbc.M004376200 |
0.359 |
|
| 2000 |
Hanada M, Ninomiya-Tsuji J, Komaki K, Ohnishi M, Katsura K, Kanamaru R, Matsumoto K, Tamura S. Regulation of the TAK1 signaling pathway by protein phosphatase 2C. The Journal of Biological Chemistry. 276: 5753-9. PMID 11104763 DOI: 10.1074/Jbc.M007773200 |
0.47 |
|
| 2000 |
Mochida Y, Takeda K, Saitoh M, Nishitoh H, Amagasa T, Ninomiya-Tsuji J, Matsumoto K, Ichijo H. ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction. The Journal of Biological Chemistry. 275: 32747-52. PMID 10921914 DOI: 10.1074/JBC.M003042200 |
0.383 |
|
| 2000 |
Takaesu G, Kishida S, Hiyama A, Yamaguchi K, Shibuya H, Irie K, Ninomiya-Tsuji J, Matsumoto K. TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Molecular Cell. 5: 649-58. PMID 10882101 DOI: 10.1016/S1097-2765(00)80244-0 |
0.36 |
|
| 2000 |
Dan I, Watanabe NM, Kobayashi T, Yamashita-Suzuki K, Fukagaya Y, Kajikawa E, Kimura WK, Nakashima TM, Matsumoto K, Ninomiya-Tsuji J, Kusumi A. Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development. Febs Letters. 469: 19-23. PMID 10708748 DOI: 10.1016/S0014-5793(00)01247-3 |
0.358 |
|
| 2000 |
Kishimoto K, Matsumoto K, Ninomiya-Tsuji J. TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop. The Journal of Biological Chemistry. 275: 7359-64. PMID 10702308 DOI: 10.1074/Jbc.275.10.7359 |
0.42 |
|
| 1999 |
Ishitani T, Ninomiya-Tsuji J, Nagai S, Nishita M, Meneghini M, Barker N, Waterman M, Bowerman B, Clevers H, Shibuya H, Matsumoto K. The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. Nature. 399: 798-802. PMID 10391247 DOI: 10.1038/21674 |
0.434 |
|
| 1999 |
Meneghini MD, Ishitani T, Carter JC, Hisamoto N, Ninomiya-Tsuji J, Thorpe CJ, Hamill DR, Matsumoto K, Bowerman B. MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans. Nature. 399: 793-7. PMID 10391246 DOI: 10.1038/21666 |
0.48 |
|
| 1999 |
Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K. The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature. 398: 252-6. PMID 10094049 DOI: 10.1038/18465 |
0.434 |
|
| 1999 |
Yamaguchi K, Nagai S, Ninomiya-Tsuji J, Nishita M, Tamai K, Irie K, Ueno N, Nishida E, Shibuya H, Matsumoto K. XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. The Embo Journal. 18: 179-87. PMID 9878061 DOI: 10.1093/emboj/18.1.179 |
0.323 |
|
| 1998 |
Nomoto S, Watanabe Y, Ninomiya-Tsuji J, Yang LX, Nagai Y, Kiuchi K, Hagiwara M, Hidaka H, Matsumoto K, Irie K. Functional analyses of mammalian protein kinase C isozymes in budding yeast and mammalian fibroblasts. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 2: 601-14. PMID 9427282 DOI: 10.1046/J.1365-2443.1997.1470346.X |
0.438 |
|
| 1997 |
Ota T, Maeda M, Odashima S, Ninomiya-Tsuji J, Tatsuka M. G1 phase-specific suppression of the Cdk2 activity by ginsenoside Rh2 in cultured murine cells. Life Sciences. 60: PL39-44. PMID 9000124 DOI: 10.1016/S0024-3205(96)00608-X |
0.309 |
|
| 1993 |
Ninomiya-Tsuji J, Torti FM, Ringold GM. Tumor necrosis factor-induced c-myc expression in the absence of mitogenesis is associated with inhibition of adipocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 90: 9611-5. PMID 8415749 DOI: 10.1073/Pnas.90.20.9611 |
0.385 |
|
| 1993 |
Tsuji Y, Ninomiya-Tsuji J, Torti SV, Torti FM. Selective loss of CDC2 and CDK2 induction by tumor necrosis factor-α in senescent human diploid fibroblasts Experimental Cell Research. 209: 175-182. PMID 8262134 DOI: 10.1006/Excr.1993.1299 |
0.447 |
|
| 1993 |
Yasuda H, Nakata T, Kamijo M, Honda R, Nakamura M, Ninomiya-Tsuji J, Yamashita M, Nagahama Y, Ohba Y. Cyclin-dependent kinase 2 (cdk2) in the murine Cdc2 kinase TS mutant. Somatic Cell and Molecular Genetics. 18: 403-8. PMID 1475706 DOI: 10.1007/Bf01233079 |
0.376 |
|
| 1992 |
Shibuya H, Yoneyama M, Ninomiya-Tsuji J, Matsumoto K, Taniguchi T. IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-myc. Cell. 70: 57-67. PMID 1535827 DOI: 10.1016/0092-8674(92)90533-I |
0.401 |
|
| 1991 |
Ninomiya-Tsuji J, Nomoto S, Yasuda H, Reed SI, Matsumoto K. Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. Proceedings of the National Academy of Sciences of the United States of America. 88: 9006-10. PMID 1717994 DOI: 10.1073/Pnas.88.20.9006 |
0.388 |
|
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