Year |
Citation |
Score |
2019 |
Pettee KM, Becker KN, Alberts AS, Reinard KA, Schroeder JL, Eisenmann KM. Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres. Cancers. 11. PMID 30897774 DOI: 10.3390/Cancers11030392 |
0.399 |
|
2018 |
LeCorgne H, Tudosie AM, Lavik K, Su R, Becker KN, Moore S, Walia Y, Wisner A, Koehler D, Alberts AS, Williams FE, Eisenmann KM. Differential Toxicity of mDia Formin-Directed Functional Agonists and Antagonists in Developing Zebrafish. Frontiers in Pharmacology. 9: 340. PMID 29692731 DOI: 10.3389/Fphar.2018.00340 |
0.416 |
|
2016 |
Erasmus JC, Bruche S, Pizarro L, Maimari N, Poggioli T, Tomlinson C, Lees J, Zalivina I, Wheeler A, Alberts A, Russo A, Braga VMM. Defining functional interactions during biogenesis of epithelial junctions. Nature Communications. 7: 13542. PMID 27922008 DOI: 10.1038/Ncomms13542 |
0.456 |
|
2016 |
Damiani D, Goffinet AM, Alberts A, Tissir F. Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors. Nature Communications. 7: 13509. PMID 27848932 DOI: 10.1038/Ncomms13509 |
0.457 |
|
2016 |
Thiam HR, Vargas P, Carpi N, Crespo CL, Raab M, Terriac E, King MC, Jacobelli J, Alberts AS, Stradal T, Lennon-Dumenil AM, Piel M. Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments. Nature Communications. 7: 10997. PMID 26975831 DOI: 10.1038/Ncomms10997 |
0.43 |
|
2016 |
Vargas P, Maiuri P, Bretou M, Sáez PJ, Pierobon P, Maurin M, Chabaud M, Lankar D, Obino D, Terriac E, Raab M, Thiam HR, Brocker T, Kitchen-Goosen SM, Alberts AS, et al. Corrigendum: Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells. Nature Cell Biology. 18: 234. PMID 26820439 DOI: 10.1038/Ncb3301 |
0.417 |
|
2016 |
Davis-Turner J, Howard AM, Alberts AS. Abstract 1867: Activation of RHO-DIAPH signaling impairs RAS-driven exosome biogenesis Cancer Research. 76: 1867-1867. DOI: 10.1158/1538-7445.Am2016-1867 |
0.379 |
|
2015 |
Vargas P, Maiuri P, Bretou M, Sáez PJ, Pierobon P, Maurin M, Chabaud M, Lankar D, Obino D, Terriac E, Raab M, Thiam HR, Brocker T, Kitchen-Goosen SM, Alberts AS, et al. Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells. Nature Cell Biology. PMID 26641718 DOI: 10.1038/Ncb3284 |
0.402 |
|
2015 |
Arden JD, Lavik KI, Rubinic KA, Chiaia N, Khuder SA, Howard MJ, Nestor-Kalinoski AL, Alberts AS, Eisenmann KM. Small molecule agonists of mammalian Diaphanous-related (mDia) formins reveal an effective glioblastoma anti-invasion strategy. Molecular Biology of the Cell. PMID 26354425 DOI: 10.1091/Mbc.E14-11-1502 |
0.405 |
|
2015 |
Ercan-Sencicek AG, Jambi S, Franjic D, Nishimura S, Li M, El-Fishawy P, Morgan TM, Sanders SJ, Bilguvar K, Suri M, Johnson MH, Gupta AR, Yuksel Z, Mane S, Grigorenko E, ... ... Alberts AS, et al. Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans. European Journal of Human Genetics : Ejhg. 23: 165-72. PMID 24781755 DOI: 10.1038/Ejhg.2014.82 |
0.451 |
|
2015 |
Turner JD, Kitchen-Goosen SM, Howard AM, Schumacher HL, Alberts AS. Abstract 4194: APC and DIAPH1 collaborate to suppress myelodysplastic syndrome (MDS) pathogenesis Cancer Research. 75: 4194-4194. DOI: 10.1158/1538-7445.Am2015-4194 |
0.49 |
|
2014 |
Pan J, Lordier L, Meyran D, Rameau P, Lecluse Y, Kitchen-Goosen S, Badirou I, Mokrani H, Narumiya S, Alberts AS, Vainchenker W, Chang Y. The formin DIAPH1 (mDia1) regulates megakaryocyte proplatelet formation by remodeling the actin and microtubule cytoskeletons. Blood. 124: 3967-77. PMID 25298036 DOI: 10.1182/Blood-2013-12-544924 |
0.517 |
|
2014 |
Kher SS, Struckhoff AP, Alberts AS, Worthylake RA. A novel role for p115RhoGEF in regulation of epithelial plasticity. Plos One. 9: e85409. PMID 24465552 DOI: 10.1371/Journal.Pone.0085409 |
0.44 |
|
2013 |
Dong B, Zhang SS, Gao W, Su H, Chen J, Jin F, Bhargava A, Chen X, Jorgensen L, Alberts AS, Zhang J, Siminovitch KA. Mammalian diaphanous-related formin 1 regulates GSK3β-dependent microtubule dynamics required for T cell migratory polarization. Plos One. 8: e80500. PMID 24260404 DOI: 10.1371/Journal.Pone.0080500 |
0.425 |
|
2013 |
Lash LL, Wallar BJ, Turner JD, Vroegop SM, Kilkuskie RE, Kitchen-Goosen SM, Xu HE, Alberts AS. Small-molecule intramimics of formin autoinhibition: a new strategy to target the cytoskeletal remodeling machinery in cancer cells. Cancer Research. 73: 6793-803. PMID 24242070 DOI: 10.1158/0008-5472.Can-13-1593 |
0.481 |
|
2013 |
Lash LL, Alberts AS. Abstract 2130: Small molecule activation of diaphanous-related formins as a novel anti-cancer strategy. Cancer Research. 73: 2130-2130. DOI: 10.1158/1538-7445.Am2013-2130 |
0.489 |
|
2012 |
Touré F, Fritz G, Li Q, Rai V, Daffu G, Zou YS, Rosario R, Ramasamy R, Alberts AS, Yan SF, Schmidt AM. Formin mDia1 mediates vascular remodeling via integration of oxidative and signal transduction pathways. Circulation Research. 110: 1279-93. PMID 22511750 DOI: 10.1161/Circresaha.111.262519 |
0.43 |
|
2012 |
Lash-VanWhye L, Kitchen-Goosen S, Alberts AS. Abstract 4764: Targeting formin autoinhibition to construct cell infrastructure Cancer Research. 72: 4764-4764. DOI: 10.1158/1538-7445.Am2012-4764 |
0.48 |
|
2012 |
Kitchen-Goosen SM, Sternberger SC, Alberts AS. Abstract 3280: Loss of the tumor suppressor APC in cells expressing lysozyme M results in murine endometrial hyperplasia Cancer Research. 72: 3280-3280. DOI: 10.1158/1538-7445.Am2012-3280 |
0.416 |
|
2010 |
DeWard AD, Eisenmann KM, Matheson SF, Alberts AS. The role of formins in human disease. Biochimica Et Biophysica Acta. 1803: 226-33. PMID 19941910 DOI: 10.1016/J.Bbamcr.2009.11.006 |
0.741 |
|
2010 |
Wyhe LL, Alberts AS. Abstract 2539: Reactivating tumor suppression with small-molecule deregulators of the Rho-regulated diaphanous-related formin autoinhibitory mechanism Cancer Research. 70: 2539-2539. DOI: 10.1158/1538-7445.Am10-2539 |
0.502 |
|
2009 |
DeWard AD, Leali K, West RA, Prendergast GC, Alberts AS. Loss of RhoB expression enhances the myelodysplastic phenotype of mammalian diaphanous-related Formin mDia1 knockout mice. Plos One. 4: e7102. PMID 19768111 DOI: 10.1371/Journal.Pone.0007102 |
0.702 |
|
2009 |
Eisenmann KM, Dykema KJ, Matheson SF, Kent NF, DeWard AD, West RA, Tibes R, Furge KA, Alberts AS. 5q- myelodysplastic syndromes: chromosome 5q genes direct a tumor-suppression network sensing actin dynamics. Oncogene. 28: 3429-41. PMID 19597464 DOI: 10.1038/Onc.2009.207 |
0.703 |
|
2009 |
DeWard AD, Alberts AS. Ubiquitin-mediated degradation of the formin mDia2 upon completion of cell division. The Journal of Biological Chemistry. 284: 20061-9. PMID 19457867 DOI: 10.1074/Jbc.M109.000885 |
0.764 |
|
2009 |
Shi Y, Zhang J, Mullin M, Dong B, Alberts AS, Siminovitch KA. The mDial formin is required for neutrophil polarization, migration, and activation of the LARG/RhoA/ROCK signaling axis during chemotaxis. Journal of Immunology (Baltimore, Md. : 1950). 182: 3837-45. PMID 19265163 DOI: 10.4049/Jimmunol.0803838 |
0.493 |
|
2009 |
Shi Y, Dong B, Miliotis H, Liu J, Alberts AS, Zhang J, Siminovitch KA. Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophils. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 207-16. PMID 19234535 DOI: 10.1139/O08-130 |
0.373 |
|
2008 |
DeWard AD, Alberts AS. Microtubule stabilization: formins assert their independence. Current Biology : Cb. 18: R605-8. PMID 18644336 DOI: 10.1016/J.Cub.2008.06.001 |
0.742 |
|
2008 |
Wang P, Bowl MR, Bender S, Peng J, Farber L, Chen J, Ali A, Zhang Z, Alberts AS, Thakker RV, Shilatifard A, Williams BO, Teh BT. Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice. Molecular and Cellular Biology. 28: 2930-40. PMID 18212049 DOI: 10.1128/Mcb.00654-07 |
0.346 |
|
2007 |
Dent EW, Kwiatkowski AV, Mebane LM, Philippar U, Barzik M, Rubinson DA, Gupton S, Van Veen JE, Furman C, Zhang J, Alberts AS, Mori S, Gertler FB. Filopodia are required for cortical neurite initiation. Nature Cell Biology. 9: 1347-59. PMID 18026093 DOI: 10.1038/Ncb1654 |
0.425 |
|
2007 |
Gupton SL, Eisenmann K, Alberts AS, Waterman-Storer CM. mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration. Journal of Cell Science. 120: 3475-87. PMID 17855386 DOI: 10.1242/Jcs.006049 |
0.521 |
|
2007 |
Kamasani U, Duhadaway JB, Alberts AS, Prendergast GC. mDia function is critical for the cell suicide program triggered by farnesyl transferase inhibition. Cancer Biology & Therapy. 6: 1422-7. PMID 17786040 DOI: 10.4161/Cbt.6.9.4546 |
0.362 |
|
2007 |
Peng J, Kitchen SM, West RA, Sigler R, Eisenmann KM, Alberts AS. Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1. Cancer Research. 67: 7565-71. PMID 17699759 DOI: 10.1158/0008-5472.Can-07-1467 |
0.453 |
|
2007 |
Eisenmann KM, West RA, Hildebrand D, Kitchen SM, Peng J, Sigler R, Zhang J, Siminovitch KA, Alberts AS. T cell responses in mammalian diaphanous-related formin mDia1 knock-out mice. The Journal of Biological Chemistry. 282: 25152-8. PMID 17595162 DOI: 10.1074/Jbc.M703243200 |
0.449 |
|
2007 |
Eisenmann KM, Harris ES, Kitchen SM, Holman HA, Higgs HN, Alberts AS. Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex. Current Biology : Cb. 17: 579-91. PMID 17398099 DOI: 10.1016/J.Cub.2007.03.024 |
0.427 |
|
2007 |
Wallar BJ, Deward AD, Resau JH, Alberts AS. RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking. Experimental Cell Research. 313: 560-71. PMID 17198702 DOI: 10.1016/J.Yexcr.2006.10.033 |
0.748 |
|
2006 |
Wallar BJ, Stropich BN, Schoenherr JA, Holman HA, Kitchen SM, Alberts AS. The basic region of the diaphanous-autoregulatory domain (DAD) is required for autoregulatory interactions with the diaphanous-related formin inhibitory domain. The Journal of Biological Chemistry. 281: 4300-7. PMID 16361707 DOI: 10.1074/Jbc.M510277200 |
0.36 |
|
2005 |
Eisenmann KM, Peng J, Wallar BJ, Alberts AS. Rho GTPase-formin pairs in cytoskeletal remodelling. Novartis Foundation Symposium. 269: 206-218; discussion . PMID 16358408 DOI: 10.1002/047001766X.Ch16 |
0.47 |
|
2005 |
Colucci-Guyon E, Niedergang F, Wallar BJ, Peng J, Alberts AS, Chavrier P. A role for mammalian diaphanous-related formins in complement receptor (CR3)-mediated phagocytosis in macrophages. Current Biology : Cb. 15: 2007-12. PMID 16303559 DOI: 10.1016/J.Cub.2005.09.051 |
0.43 |
|
2005 |
Alberts AS, Qin H, Carr HS, Frost JA. PAK1 negatively regulates the activity of the Rho exchange factor NET1. The Journal of Biological Chemistry. 280: 12152-61. PMID 15684429 DOI: 10.1074/jbc.M405073200 |
0.338 |
|
2004 |
Wen Y, Eng CH, Schmoranzer J, Cabrera-Poch N, Morris EJ, Chen M, Wallar BJ, Alberts AS, Gundersen GG. EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration. Nature Cell Biology. 6: 820-30. PMID 15311282 DOI: 10.1038/Ncb1160 |
0.456 |
|
2003 |
Chen J, Lui WO, Vos MD, Clark GJ, Takahashi M, Schoumans J, Khoo SK, Petillo D, Lavery T, Sugimura J, Astuti D, Zhang C, Kagawa S, Maher ER, Larsson C, ... Alberts AS, et al. The t(1;3) breakpoint-spanning genes LSAMP and NORE1 are involved in clear cell renal cell carcinomas. Cancer Cell. 4: 405-13. PMID 14667507 DOI: 10.1016/S1535-6108(03)00269-1 |
0.343 |
|
2003 |
Wallar BJ, Alberts AS. The formins: active scaffolds that remodel the cytoskeleton. Trends in Cell Biology. 13: 435-46. PMID 12888296 DOI: 10.1016/S0962-8924(03)00153-3 |
0.518 |
|
2003 |
Peng J, Wallar BJ, Flanders A, Swiatek PJ, Alberts AS. Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42. Current Biology : Cb. 13: 534-45. PMID 12676083 DOI: 10.1016/S0960-9822(03)00170-2 |
0.438 |
|
2002 |
Alberts AS. Diaphanous-related Formin homology proteins. Current Biology : Cb. 12: R796. PMID 12477401 DOI: 10.1016/S0960-9822(02)01309-X |
0.53 |
|
2001 |
Palazzo AF, Joseph HL, Chen YJ, Dujardin DL, Alberts AS, Pfister KK, Vallee RB, Gundersen GG. Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Current Biology : Cb. 11: 1536-41. PMID 11591323 DOI: 10.1016/S0960-9822(01)00475-4 |
0.475 |
|
2001 |
Palazzo AF, Cook TA, Alberts AS, Gundersen GG. mDia mediates Rho-regulated formation and orientation of stable microtubules. Nature Cell Biology. 3: 723-9. PMID 11483957 DOI: 10.1038/35087035 |
0.464 |
|
2001 |
Alberts AS. Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain. The Journal of Biological Chemistry. 276: 2824-30. PMID 11035012 DOI: 10.1074/Jbc.M006205200 |
0.44 |
|
2000 |
Fackler OT, Lu X, Frost JA, Geyer M, Jiang B, Luo W, Abo A, Alberts AS, Peterlin BM. p21-activated kinase 1 plays a critical role in cellular activation by Nef. Molecular and Cellular Biology. 20: 2619-27. PMID 10713183 DOI: 10.1128/Mcb.20.7.2619-2627.2000 |
0.347 |
|
2000 |
Tominaga T, Sahai E, Chardin P, McCormick F, Courtneidge SA, Alberts AS. Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling. Molecular Cell. 5: 13-25. PMID 10678165 DOI: 10.1016/S1097-2765(00)80399-8 |
0.403 |
|
1999 |
Fackler OT, Luo W, Geyer M, Alberts AS, Peterlin BM. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Molecular Cell. 3: 729-39. PMID 10394361 DOI: 10.1016/S1097-2765(01)80005-8 |
0.382 |
|
1998 |
Alberts AS, Treisman R. Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1. The Embo Journal. 17: 4075-85. PMID 9670022 DOI: 10.1093/Emboj/17.14.4075 |
0.391 |
|
1998 |
Sahai E, Alberts AS, Treisman R. RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation. The Embo Journal. 17: 1350-61. PMID 9482732 DOI: 10.1093/Emboj/17.5.1350 |
0.321 |
|
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