Jonathan H. Jaggar - Publications

Affiliations: 
Molecular, Cellular, and Systems Physiology University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Physiology Biology, Cell Biology

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mata-Daboin A, Garrud TAC, Fernandez-Pena C, Peixoto-Neves D, Leo MD, Bernardelli AK, Singh P, Malik KU, Jaggar JH. Vasodilators activate the anion channel TMEM16A in endothelial cells to reduce blood pressure. Science Signaling. 16: eadh9399. PMID 37963195 DOI: 10.1126/scisignal.adh9399  0.454
2023 Mbiakop UC, Jaggar JH. Vascular polycystin proteins in health and disease. Microcirculation (New York, N.Y. : 1994). e12834. PMID 37823335 DOI: 10.1111/micc.12834  0.301
2023 Peixoto-Neves D, Jaggar JH. Physiological functions and pathological involvement of ion channel trafficking in the vasculature. The Journal of Physiology. PMID 37818949 DOI: 10.1113/JP285007  0.376
2023 Akin EJ, Aoun J, Jimenez C, Mayne K, Baeck J, Young MD, Sullivan B, Sanders KM, Ward SM, Bulley S, Jaggar JH, Earley S, Greenwood IA, Leblanc N. ANO1, CaV1.2, and IP3R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle. The Journal of General Physiology. 155. PMID 37702787 DOI: 10.1085/jgp.202213217  0.502
2023 Peixoto-Neves D, Yadav S, MacKay CE, Mbiakop UC, Mata-Daboin A, Leo MD, Jaggar JH. Vasodilators mobilize SK3 channels in endothelial cells to produce arterial relaxation. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303238120. PMID 37494394 DOI: 10.1073/pnas.2303238120  0.443
2023 Mata-Daboin A, Garrud TAC, Fernandez-Pena C, Peixoto-Neves D, Leo MD, Bernardelli AK, Singh P, Malik KU, Jaggar JH. Vasodilators activate TMEM16A channels in endothelial cells to reduce blood pressure. Biorxiv : the Preprint Server For Biology. PMID 37333248 DOI: 10.1101/2023.06.02.543450  0.44
2022 MacKay CE, Floen M, Leo MD, Hasan R, Garrud TAC, Fernández-Peña C, Singh P, Malik KU, Jaggar JH. A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation. Elife. 11. PMID 35229718 DOI: 10.7554/eLife.74765  0.315
2021 Bukiya AN, Leo MD, Jaggar JH, Dopico AM. Cholesterol activates BK channels by increasing KCNMB1 protein levels in the plasmalemma. The Journal of Biological Chemistry. 100381. PMID 33556372 DOI: 10.1016/j.jbc.2021.100381  0.473
2021 Leo MD, Peixoto-Neves D, Yin W, Raghavan S, Muralidharan P, Mata-Daboin A, Jaggar JH. TMEM16A channel upregulation in arterial smooth muscle cells produces vasoconstriction during diabetes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33449847 DOI: 10.1152/ajpheart.00690.2020  0.326
2020 Bulley S, Fernández-Peña C, Hasan R, Leo MD, Muralidharan P, MacKay CE, Evanson KW, Moreira-Junior L, Mata-Daboin A, Burris SK, Wang Q, Kuruvilla KP, Jaggar JH. Correction: Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure. Elife. 9. PMID 32602835 DOI: 10.7554/Elife.60403  0.461
2020 MacKay CE, Leo MD, Fernández-Peña C, Hasan R, Yin W, Mata-Daboin A, Bulley S, Gammons J, Mancarella S, Jaggar JH. Intravascular flow stimulates PKD2 (polycystin-2) channels in endothelial cells to reduce blood pressure. Elife. 9. PMID 32364494 DOI: 10.7554/Elife.56655  0.463
2020 Aoun J, Mayne K, Baeck J, Sanders KM, Ward SM, Greenwood IA, Bulley SA, Jaggar JH, Earley S, Leblanc N. ANO1, CaV1.2 and IP3R Form a Functional Unit of Excitation-Contraction Coupling during Agonist-Mediated Contraction of Mouse Pulmonary Arterial Smooth Muscle Biophysical Journal. 118: 563a-564a. DOI: 10.1016/J.Bpj.2019.11.3074  0.387
2019 Hasan R, Leo MD, Muralidharan P, Mata-Daboin A, Yin W, Bulley S, Fernandez-Peña C, MacKay CE, Jaggar JH. SUMO1 modification of PKD2 channels regulates arterial contractility. Proceedings of the National Academy of Sciences of the United States of America. PMID 31822608 DOI: 10.1073/Pnas.1917264116  0.48
2019 Zawieja SD, Castorena JA, Gui P, Li M, Bulley SA, Jaggar JH, Rock JR, Davis MJ. Ano1 mediates pressure-sensitive contraction frequency changes in mouse lymphatic collecting vessels. The Journal of General Physiology. PMID 30862712 DOI: 10.1085/jgp.201812294  0.359
2018 Bulley S, Fernández-Peña C, Hasan R, Leo MD, Muralidharan P, Mackay CE, Evanson KW, Moreira-Junior L, Mata-Daboin A, Burris SK, Wang Q, Kuruvilla KP, Jaggar JH. Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure. Elife. 7. PMID 30511640 DOI: 10.7554/Elife.42628  0.375
2018 Leo MD, Zhai X, Yin W, Jaggar JH. Impaired Trafficking of β1 Subunits Inhibits BK Channels in Cerebral Arteries of Hypertensive Rats. Hypertension (Dallas, Tex. : 1979). PMID 30012867 DOI: 10.1161/HYPERTENSIONAHA.118.11147  0.396
2018 Dopico AM, Bukiya AN, Jaggar JH. Calcium- and voltage-gated BK channels in vascular smooth muscle. Pflugers Archiv : European Journal of Physiology. PMID 29748711 DOI: 10.1007/s00424-018-2151-y  0.409
2018 Bulley S, Fernández-Peña C, Hasan R, Leo MD, Muralidharan P, Mackay CE, Evanson KW, Moreira-Junior L, Mata-Daboin A, Burris SK, Wang Q, Kuruvilla KP, Jaggar JH. Author response: Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure Elife. DOI: 10.7554/Elife.42628.023  0.454
2018 Mayne K, Young MD, Grainger N, Baeck JC, Sanders KM, Ward SM, Greenwood IA, Bulley SA, Jaggar JH, Leblanc N. Role of the CaCC Channel ANO1 in Electromechanical Coupling of Murine Pulmonary Artery Smooth Muscle Biophysical Journal. 114: 41a. DOI: 10.1016/J.Bpj.2017.11.273  0.452
2017 Leo MD, Jaggar JH. Trafficking of BK channel subunits controls arterial contractility. Oncotarget. 8: 106149-106150. PMID 29290926 DOI: 10.18632/oncotarget.22280  0.376
2017 Hasan R, Jaggar JH. KV channel trafficking and control of vascular tone. Microcirculation (New York, N.Y. : 1994). PMID 28963858 DOI: 10.1111/Micc.12418  0.581
2017 Zhai X, Leo MD, Jaggar JH. Endothelin-1 Stimulates Vasoconstriction Through Rab11A Serine 177 Phosphorylation. Circulation Research. PMID 28696251 DOI: 10.1161/CIRCRESAHA.117.311102  0.397
2017 Leo MD, Zhai X, Muralidharan P, Kuruvilla KP, Bulley S, Boop FA, Jaggar JH. Membrane depolarization activates BK channels through ROCK-mediated β1 subunit surface trafficking to limit vasoconstriction. Science Signaling. 10. PMID 28487419 DOI: 10.1126/Scisignal.Aah5417  0.492
2017 Jaggar JH, VanHook AM. Science Signaling Podcast for 9 May 2017: Trafficking of BK channel subunits in arterial myocytes. Science Signaling. 10. PMID 28487418 DOI: 10.1126/Scisignal.Aan4849  0.478
2017 Hasan R, Leeson-Payne ATS, Jaggar JH, Zhang X. Corrigendum: Calmodulin is responsible for Ca(2+)-dependent regulation of TRPA1 Channels. Scientific Reports. 7: 46588. PMID 28471425 DOI: 10.1038/Srep46588  0.434
2017 Hasan R, Leeson-Payne AT, Jaggar JH, Zhang X. Calmodulin is responsible for Ca(2+)-dependent regulation of TRPA1 Channels. Scientific Reports. 7: 45098. PMID 28332600 DOI: 10.1038/Srep45098  0.519
2016 Kidd MW, Bulley S, Jaggar JH. Angiotensin II reduces the surface abundance of KV1.5 channels in arterial myocytes to stimulate vasoconstriction. The Journal of Physiology. PMID 27958660 DOI: 10.1113/Jp272893  0.416
2016 Samak G, Gangwar R, Meena AS, Rao RG, Shukla PK, Manda B, Narayanan D, Jaggar JH, Rao R. Calcium Channels and Oxidative Stress Mediate a Synergistic Disruption of Tight Junctions by Ethanol and Acetaldehyde in Caco-2 Cell Monolayers. Scientific Reports. 6: 38899. PMID 27958326 DOI: 10.1038/Srep38899  0.613
2016 Wang Q, Leo MD, Narayanan D, Kuruvilla KP, Jaggar JH. Local coupling of TRPC6 to ANO1/TMEM16A channels in smooth muscle cells amplifies vasoconstriction in cerebral arteries. American Journal of Physiology. Cell Physiology. ajpcell.00092.2016. PMID 27147559 DOI: 10.1152/Ajpcell.00092.2016  0.759
2016 Bannister JP, Bulley S, Leo MD, Kidd MW, Jaggar JH. Rab25 influences functional CaV1.2 channel surface expression in arterial smooth muscle cells. American Journal of Physiology. Cell Physiology. ajpcell.00345.2015. PMID 27076616 DOI: 10.1152/Ajpcell.00345.2015  0.544
2015 Kidd MW, Leo MD, Bannister JP, Jaggar JH. Intravascular pressure enhances the abundance of functional Kv1.5 channels at the surface of arterial smooth muscle cells. Science Signaling. 8: ra83. PMID 26286025 DOI: 10.1126/scisignal.aac5128  0.378
2015 Leo MD, Bulley S, Bannister JP, Kuruvilla KP, Narayanan D, Jaggar JH. Angiotensin II stimulates internalization and degradation of arterial myocyte plasma membrane BK channels to induce vasoconstriction. American Journal of Physiology. Cell Physiology. 309: C392-402. PMID 26179602 DOI: 10.1152/Ajpcell.00127.2015  0.698
2015 Peixoto-Neves D, Wang Q, Leal-Cardoso JH, Rossoni LV, Jaggar JH. Eugenol dilates mesenteric arteries and reduces systemic BP by activating endothelial cell TRPV4 channels. British Journal of Pharmacology. 172: 3484-94. PMID 25832173 DOI: 10.1111/Bph.13156  0.507
2015 Burris SK, Wang Q, Bulley S, Neeb ZP, Jaggar JH. 9-Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels. British Journal of Pharmacology. 172: 2459-68. PMID 25573456 DOI: 10.1111/Bph.13077  0.534
2015 Sullivan MN, Gonzales AL, Pires PW, Bruhl A, Leo MD, Li W, Oulidi A, Boop FA, Feng Y, Jaggar JH, Welsh DG, Earley S. Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation. Science Signaling. 8: ra2. PMID 25564678 DOI: 10.1126/Scisignal.2005659  0.608
2015 Samak G, Chaudhry KK, Gangwar R, Narayanan D, Jaggar JH, Rao R. Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium. The Biochemical Journal. 465: 503-15. PMID 25377781 DOI: 10.1042/Bj20140450  0.655
2014 Nnorom CC, Davis C, Fedinec AL, Howell K, Jaggar JH, Parfenova H, Pourcyrous M, Leffler CW. Contributions of KATP and KCa channels to cerebral arteriolar dilation to hypercapnia in neonatal brain. Physiological Reports. 2. PMID 25168876 DOI: 10.14814/Phy2.12127  0.457
2014 Bannister JP, Adebiyi A, Zhao G, Narayanan D, Thomas CM, Feng JY, Jaggar J. Erratum: Smooth muscle cell α2δ-1 subunits are essential for vasoregulation by CaV1.2 channels (Circulation Research (2009) 105 (948-955) DOI: 10.1161/CIRCRESAHA.109.203620) Circulation Research. 115. PMID 25124325 DOI: 10.1161/Res.0000000000000032  0.673
2014 Nourian Z, Li M, Leo MD, Jaggar JH, Braun AP, Hill MA. Large conductance Ca2+-activated K+ channel (BKCa) α-subunit splice variants in resistance arteries from rat cerebral and skeletal muscle vasculature. Plos One. 9: e98863. PMID 24921651 DOI: 10.1371/Journal.Pone.0098863  0.478
2014 Peixoto-Neves D, Leal-Cardoso JH, Jaggar JH. Eugenol dilates rat cerebral arteries by inhibiting smooth muscle cell voltage-dependent calcium channels. Journal of Cardiovascular Pharmacology. 64: 401-6. PMID 24921632 DOI: 10.1097/Fjc.0000000000000131  0.555
2014 Evanson KW, Bannister JP, Leo MD, Jaggar JH. LRRC26 is a functional BK channel auxiliary γ subunit in arterial smooth muscle cells. Circulation Research. 115: 423-31. PMID 24906643 DOI: 10.1161/CIRCRESAHA.115.303407  0.526
2014 Ye Y, Jian K, Jaggar JH, Bukiya AN, Dopico AM. Type 2 ryanodine receptors are highly sensitive to alcohol. Febs Letters. 588: 1659-65. PMID 24631538 DOI: 10.1016/J.Febslet.2014.03.005  0.452
2014 Leo MD, Bannister JP, Narayanan D, Nair A, Grubbs JE, Gabrick KS, Boop FA, Jaggar JH. Dynamic regulation of β1 subunit trafficking controls vascular contractility. Proceedings of the National Academy of Sciences of the United States of America. 111: 2361-6. PMID 24464482 DOI: 10.1073/Pnas.1317527111  0.688
2014 Bulley S, Jaggar JH. Cl⁻ channels in smooth muscle cells. PflüGers Archiv : European Journal of Physiology. 466: 861-72. PMID 24077695 DOI: 10.1007/S00424-013-1357-2  0.524
2014 Evanson KW, Bannister JP, Leo MD, Jaggar JH. LRRC26 is a functional BK channel auxiliary γ subunit in arterial smooth muscle cells Circulation Research. 115: 423-431. DOI: 10.1161/CIRCRESAHA.115.303407  0.546
2014 Leo MD, Bannister JP, Narayanan D, Nair A, Grubbs JE, Gabrick KS, Boop F, Jaggar J. Erratum: Dynamic regulation of β1 subunit trafficking controls vascular contractility (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (2361-2366) DOI:10.1073/pnas.1317527111) Proceedings of the National Academy of Sciences of the United States of America. 111. DOI: 10.1073/Pnas.1407537111  0.575
2014 Bulley S, Jaggar JH. Erratum to: Cl− channels in smooth muscle cells PflüGers Archiv - European Journal of Physiology. 466: 873-873. DOI: 10.1007/S00424-014-1518-Y  0.445
2013 Narayanan D, Bulley S, Leo MD, Burris SK, Gabrick KS, Boop FA, Jaggar JH. Smooth muscle cell transient receptor potential polycystin-2 (TRPP2) channels contribute to the myogenic response in cerebral arteries. The Journal of Physiology. 591: 5031-46. PMID 23858011 DOI: 10.1113/Jphysiol.2013.258319  0.711
2013 Bannister JP, Leo MD, Narayanan D, Jangsangthong W, Nair A, Evanson KW, Pachuau J, Gabrick KS, Boop FA, Jaggar JH. The voltage-dependent L-type Ca2+ (CaV1.2) channel C-terminus fragment is a bi-modal vasodilator. The Journal of Physiology. 591: 2987-98. PMID 23568894 DOI: 10.1113/Jphysiol.2013.251926  0.754
2013 Schwingshackl A, Teng B, Ghosh M, Lim KG, Tigyi G, Narayanan D, Jaggar JH, Waters CM. Regulation of interleukin-6 secretion by the two-pore-domain potassium channel Trek-1 in alveolar epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L276-86. PMID 23275623 DOI: 10.1152/Ajplung.00299.2012  0.646
2012 Adebiyi A, Thomas-Gatewood CM, Leo MD, Kidd MW, Neeb ZP, Jaggar JH. An elevation in physical coupling of type 1 inositol 1,4,5-trisphosphate (IP3) receptors to transient receptor potential 3 (TRPC3) channels constricts mesenteric arteries in genetic hypertension. Hypertension. 60: 1213-9. PMID 23045459 DOI: 10.1161/Hypertensionaha.112.198820  0.518
2012 Bannister JP, Bulley S, Narayanan D, Thomas-Gatewood C, Luzny P, Pachuau J, Jaggar JH. Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension. Hypertension. 60: 1006-15. PMID 22949532 DOI: 10.1161/Hypertensionaha.112.199661  0.692
2012 Bulley S, Neeb ZP, Burris SK, Bannister JP, Thomas-Gatewood CM, Jangsangthong W, Jaggar JH. TMEM16A/ANO1 channels contribute to the myogenic response in cerebral arteries. Circulation Research. 111: 1027-36. PMID 22872152 DOI: 10.1161/Circresaha.112.277145  0.497
2012 Liang GH, Xi Q, Leffler CW, Jaggar JH. Hydrogen sulfide activates Ca2+ sparks to induce cerebral arteriole dilatation Journal of Physiology. 590: 2709-2720. PMID 22508960 DOI: 10.1113/Jphysiol.2011.225128  0.55
2012 Narayanan D, Adebiyi A, Jaggar JH. Inositol trisphosphate receptors in smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology. 302: H2190-210. PMID 22447942 DOI: 10.1152/Ajpheart.01146.2011  0.738
2012 Samak G, Narayanan D, Jaggar JH, Rao R. Ca V1.3 channels and intracellular calcium mediate osmotic stress-induced N-terminal c-Jun kinase activation and disruption of tight junctions in Caco-2 cell monolayers (The Journal of Biological Chemistry (2011) 286, (30232-30243)) Journal of Biological Chemistry. 287: 5181. DOI: 10.1074/Jbc.A111.240358  0.71
2012 Liang G, xi Q, Leffler C, Jaggar J. P6 Hydrogen sulfide activates Ca2+ sparks to induce cerebral arteriole dilation Nitric Oxide. 27. DOI: 10.1016/J.Niox.2012.08.007  0.544
2011 Thomas-Gatewood C, Neeb ZP, Bulley S, Adebiyi A, Bannister JP, Leo MD, Jaggar JH. TMEM16A channels generate Ca²⁺-activated Cl⁻ currents in cerebral artery smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1819-27. PMID 21856902 DOI: 10.1152/Ajpheart.00404.2011  0.608
2011 Adebiyi A, McNally EM, Jaggar JH. Vasodilation induced by oxygen/glucose deprivation is attenuated in cerebral arteries of SUR2 null mice. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1360-8. PMID 21784985 DOI: 10.1152/Ajpheart.00406.2011  0.462
2011 Samak G, Narayanan D, Jaggar JH, Rao R. CaV1.3 channels and intracellular calcium mediate osmotic stress-induced N-terminal c-Jun kinase activation and disruption of tight junctions in Caco-2 CELL MONOLAYERS. The Journal of Biological Chemistry. 286: 30232-43. PMID 21737448 DOI: 10.1074/Jbc.M111.240358  0.723
2011 Xi Q, Tcheranova D, Basuroy S, Parfenova H, Jaggar JH, Leffler CW. Glutamate-induced calcium signals stimulate CO production in piglet astrocytes. American Journal of Physiology. Heart and Circulatory Physiology. 301: H428-33. PMID 21572018 DOI: 10.1152/Ajpheart.01277.2010  0.506
2011 Leffler CW, Parfenova H, Jaggar JH. Carbon monoxide as an endogenous vascular modulator. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1-H11. PMID 21498777 DOI: 10.1152/Ajpheart.00230.2011  0.565
2011 Liang GH, Adebiyi A, Leo MD, McNally EM, Leffler CW, Jaggar JH. Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane KATP channels. American Journal of Physiology. Heart and Circulatory Physiology. 300: H2088-95. PMID 21421823 DOI: 10.1152/Ajpheart.01290.2010  0.414
2011 Bannister JP, Thomas-Gatewood CM, Neeb ZP, Adebiyi A, Cheng X, Jaggar JH. Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. The Journal of Biological Chemistry. 286: 15058-66. PMID 21357696 DOI: 10.1074/Jbc.M110.182816  0.56
2011 Adebiyi A, Narayanan D, Jaggar JH. Caveolin-1 assembles type 1 inositol 1,4,5-trisphosphate receptors and canonical transient receptor potential 3 channels into a functional signaling complex in arterial smooth muscle cells. The Journal of Biological Chemistry. 286: 4341-8. PMID 21098487 DOI: 10.1074/Jbc.M110.179747  0.711
2011 Samak G, Narayanan D, Jaggar JH, Rao R(. CA V 1.3, the Apical Membrane Calcium Channel, Mediates Osmotic Stress-Induced Calcium Influx, JNK2 Activation and Tight Junction (TJ) Disruption in CACO-2 Cell Monolayers Gastroenterology. 140: S-502. DOI: 10.1016/S0016-5085(11)62077-5  0.697
2010 Zhao G, Neeb ZP, Dennis Leo M, Pachuau J, Adebiyi A, Ouyang K, Chen J, Jaggar JH. Type 1 IP3 receptors activate BKC3 channels via local molecular coupling in arterial smooth muscle cells Journal of General Physiology. 136: 283-291. PMID 20713546 DOI: 10.1085/Jgp.201010453  0.615
2010 Narayanan D, Xi Q, Pfeffer LM, Jaggar JH. Mitochondria control functional CaV1.2 expression in smooth muscle cells of cerebral arteries. Circulation Research. 107: 631-41. PMID 20616314 DOI: 10.1161/Circresaha.110.224345  0.73
2010 Crnich R, Amberg GC, Leo MD, Gonzales AL, Tamkun MM, Jaggar JH, Earley S. Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 299: C682-94. PMID 20610768 DOI: 10.1152/Ajpcell.00101.2010  0.495
2010 Vaithianathan T, Narayanan D, Asuncion-Chin MT, Jeyakumar LH, Liu J, Fleischer S, Jaggar JH, Dopico AM. Subtype identification and functional characterization of ryanodine receptors in rat cerebral artery myocytes. American Journal of Physiology. Cell Physiology. 299: C264-78. PMID 20445169 DOI: 10.1152/Ajpcell.00318.2009  0.7
2010 Adebiyi A, Zhao G, Narayanan D, Thomas-Gatewood CM, Bannister JP, Jaggar JH. Isoform-selective physical coupling of TRPC3 channels to IP3 receptors in smooth muscle cells regulates arterial contractility. Circulation Research. 106: 1603-12. PMID 20378853 DOI: 10.1161/Circresaha.110.216804  0.735
2010 Xi Q, Umstot E, Zhao G, Narayanan D, Leffler CW, Jaggar JH. Glutamate regulates Ca2+ signals in smooth muscle cells of newborn piglet brain slice arterioles through astrocyte- and heme oxygenase-dependent mechanisms. American Journal of Physiology. Heart and Circulatory Physiology. 298: H562-9. PMID 19966053 DOI: 10.1152/Ajpheart.00823.2009  0.717
2009 Bannister JP, Adebiyi A, Zhao G, Narayanan D, Thomas CM, Feng JY, Jaggar JH. Smooth muscle cell alpha2delta-1 subunits are essential for vasoregulation by CaV1.2 channels. Circulation Research. 105: 948-55. PMID 19797702 DOI: 10.1161/Circresaha.109.203620  0.744
2009 Cheng X, Pachuau J, Blaskova E, Asuncion-Chin M, Liu J, Dopico AM, Jaggar JH. Alternative splicing of Cav1.2 channel exons in smooth muscle cells of resistance-size arteries generates currents with unique electrophysiological properties. American Journal of Physiology. Heart and Circulatory Physiology. 297: H680-8. PMID 19502562 DOI: 10.1152/Ajpheart.00109.2009  0.555
2009 Xi Q, Adebiyi A, Zhao G, Chapman KE, Waters C, Hassid A, Jaggar J. Erratum: IP3 Constricts cerebral arteries via IP3 receptor-mediated TRPC3 channel activation and independently of sarcoplasmic reticulum Ca2+ release (Circulation Research (2008) 102 (1118-1126)) Circulation Research. 105. DOI: 10.1161/Res.0B013E3181B12Da8  0.567
2009 Zhao G, Adebiyi A, Blaskova E, Xi Q, Jaggar J. Type 1 inositol 1,4,5-trisphosphate receptors mediate UTP-induced cation currents, Ca2+ signals, and vasoconstriction in cerebral arteries (American Journal of Physiology - Cell Physiology (2008) 295, (C1376-C1384) DOI: 10.1152/ajpcell.00362.2008) American Journal of Physiology-Cell Physiology. 297. DOI: 10.1152/Ajpcell.Zh0-5991-Corr.2009  0.478
2008 Zhao G, Adebiyi A, Blaskova E, Xi Q, Jaggar JH. Type 1 inositol 1,4,5-trisphosphate receptors mediate UTP-induced cation currents, Ca2+ signals, and vasoconstriction in cerebral arteries. American Journal of Physiology. Cell Physiology. 295: C1376-84. PMID 18799650 DOI: 10.1152/Ajpcell.00362.2008  0.524
2008 Adebiyi A, McNally EM, Jaggar JH. Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers. Molecular Pharmacology. 74: 736-43. PMID 18511652 DOI: 10.1124/Mol.108.048165  0.572
2008 Xi Q, Adebiyi A, Zhao G, Chapman KE, Waters CM, Hassid A, Jaggar JH. IP3 constricts cerebral arteries via IP3 receptor-mediated TRPC3 channel activation and independently of sarcoplasmic reticulum Ca2+ release. Circulation Research. 102: 1118-26. PMID 18388325 DOI: 10.1161/Circresaha.108.173948  0.598
2008 Li A, Xi Q, Umstot ES, Bellner L, Schwartzman ML, Jaggar JH, Leffler CW. Astrocyte-derived CO is a diffusible messenger that mediates glutamate-induced cerebral arteriolar dilation by activating smooth muscle Cell KCa channels. Circulation Research. 102: 234-41. PMID 17991880 DOI: 10.1161/Circresaha.107.164145  0.523
2007 Cheng X, Liu J, Asuncion-Chin M, Blaskova E, Bannister JP, Dopico AM, Jaggar JH. A novel Ca(V)1.2 N terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits. The Journal of Biological Chemistry. 282: 29211-21. PMID 17699517 DOI: 10.1074/Jbc.M610623200  0.559
2007 Jaggar JH. Smooth muscle sparklet Ca(v) channels defined: 1.2 is the number. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1317-9. PMID 17545476 DOI: 10.1152/Ajpheart.00613.2007  0.572
2007 Zhao G, Adebiyi A, Xi Q, Jaggar JH. Hypoxia reduces KCa channel activity by inducing Ca2+ spark uncoupling in cerebral artery smooth muscle cells American Journal of Physiology - Cell Physiology. 292. PMID 17314264 DOI: 10.1152/Ajpcell.00629.2006  0.627
2007 Adebiyi A, Zhao G, Cheranov SY, Ahmed A, Jaggar JH. Caveolin-1 abolishment attenuates the myogenic response in murine cerebral arteries. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1584-92. PMID 17098833 DOI: 10.1152/Ajpheart.00584.2006  0.598
2007 Adebiyi A, Zhao G, Cheranov SY, Ahmed A, Jaggar JH. Caveolin‐1 ablation induces functional K Ca channel activation and attenuates the myogenic response in cerebral arteries The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A521  0.533
2006 Li A, Adebiyi A, Leffler CW, Jaggar JH. KCa channel insensitivity to Ca2+ sparks underlies fractional uncoupling in newborn cerebral artery smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1118-25. PMID 16603686 DOI: 10.1152/Ajpheart.01308.2005  0.619
2006 Leffler CW, Parfenova H, Jaggar JH, Wang R. Carbon monoxide and hydrogen sulfide: gaseous messengers in cerebrovascular circulation. Journal of Applied Physiology (Bethesda, Md. : 1985). 100: 1065-76. PMID 16467393 DOI: 10.1152/Japplphysiol.00793.2005  0.525
2006 Cheng X, Jaggar JH. Genetic ablation of caveolin-1 modifies Ca2+ spark coupling in murine arterial smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2309-19. PMID 16428350 DOI: 10.1152/Ajpheart.01226.2005  0.612
2006 Cheranov SY, Jaggar JH. TNF-alpha dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation. American Journal of Physiology. Cell Physiology. 290: C964-71. PMID 16267103 DOI: 10.1152/Ajpcell.00499.2005  0.532
2005 Jaggar JH, Li A, Parfenova H, Liu J, Umstot ES, Dopico AM, Leffler CW. Heme is a carbon monoxide receptor for large-conductance Ca2+-activated K+ channels. Circulation Research. 97: 805-12. PMID 16166559 DOI: 10.1161/01.Res.0000186180.47148.7B  0.585
2005 Xi Q, Cheranov SY, Jaggar JH. Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks Circulation Research. 97: 354-362. PMID 16020754 DOI: 10.1161/01.Res.0000177669.29525.78  0.57
2005 Leffler CW, Fedinec AL, Parfenova H, Jaggar JH. Permissive contributions of NO and prostacyclin in CO-induced cerebrovascular dilation in piglets. American Journal of Physiology. Heart and Circulatory Physiology. 289: H432-8. PMID 15708959 DOI: 10.1152/Ajpheart.01195.2004  0.412
2004 Liu P, Xi Q, Ahmed A, Jaggar JH, Dopico AM. Essential role for smooth muscle BK channels in alcohol-induced cerebrovascular constriction. Proceedings of the National Academy of Sciences of the United States of America. 101: 18217-22. PMID 15604147 DOI: 10.1073/Pnas.0406096102  0.532
2004 Ahmed A, Waters CM, Leffler CW, Jaggar JH. Ionic mechanisms mediating the myogenic response in newborn porcine cerebral arteries American Journal of Physiology - Heart and Circulatory Physiology. 287: H2061-H2069. PMID 15284060 DOI: 10.1152/Ajpheart.00660.2004  0.585
2004 Barkoudah E, Jaggar JH, Leffler CW. The permissive role of endothelial NO in CO-induced cerebrovascular dilation. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1459-65. PMID 15191891 DOI: 10.1152/Ajpheart.00369.2004  0.526
2004 Cheranov SY, Jaggar JH. Mitochondrial modulation of Ca2+ sparks and transient KCa currents in smooth muscle cells of rat cerebral arteries. The Journal of Physiology. 556: 755-71. PMID 14766935 DOI: 10.1113/Jphysiol.2003.059568  0.543
2004 Xi Q, Tcheranova D, Parfenova H, Horowitz B, Leffler CW, Jaggar JH. Carbon monoxide activates KCa channels in newborn arteriole smooth muscle cells by increasing apparent Ca2+ sensitivity of alpha-subunits. American Journal of Physiology. Heart and Circulatory Physiology. 286: H610-8. PMID 14563665 DOI: 10.1152/Ajpheart.00782.2003  0.584
2003 Meyer zu Heringdorf D, Liliom K, Schaefer M, Danneberg K, Jaggar JH, Tigyi G, Jakobs KH. Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors. Febs Letters. 554: 443-9. PMID 14623109 DOI: 10.1016/S0014-5793(03)01219-5  0.43
2003 Fiumana E, Parfenova H, Jaggar JH, Leffler CW. Carbon monoxide mediates vasodilator effects of glutamate in isolated pressurized cerebral arterioles of newborn pigs. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1073-9. PMID 12666665 DOI: 10.1152/Ajpheart.00881.2002  0.304
2002 Wang DA, Du H, Jaggar JH, Brindley DN, Tigyi GJ, Watsky MA. Injury-elicited differential transcriptional regulation of phospholipid growth factor receptors in the cornea. American Journal of Physiology. Cell Physiology. 283: C1646-54. PMID 12388084 DOI: 10.1152/Ajpcell.00323.2002  0.339
2002 Jaggar JH, Leffler CW, Cheranov SY, Tcheranova D, E S, Cheng X. Carbon monoxide dilates cerebral arterioles by enhancing the coupling of Ca2+ sparks to Ca2+-activated K+ channels. Circulation Research. 91: 610-7. PMID 12364389 DOI: 10.1161/01.Res.0000036900.76780.95  0.55
2002 Cheranov SY, Jaggar JH. Sarcoplasmic reticulum calcium load regulates rat arterial smooth muscle calcium sparks and transient K(Ca) currents. The Journal of Physiology. 544: 71-84. PMID 12356881 DOI: 10.1113/Jphysiol.2002.025197  0.535
2001 Jaggar JH. Intravascular pressure regulates local and global Ca(2+) signaling in cerebral artery smooth muscle cells. American Journal of Physiology. Cell Physiology. 281: C439-48. PMID 11443043 DOI: 10.1152/Ajpcell.2001.281.2.C439  0.569
2000 Jaggar JH, Nelson MT. Differential regulation of Ca(2+) sparks and Ca(2+) waves by UTP in rat cerebral artery smooth muscle cells. American Journal of Physiology. Cell Physiology. 279: C1528-39. PMID 11029300 DOI: 10.1152/Ajpcell.2000.279.5.C1528  0.542
2000 Jaggar JH, Porter VA, Lederer WJ, Nelson MT. Calcium sparks in smooth muscle. American Journal of Physiology. Cell Physiology. 278: C235-56. PMID 10666018 DOI: 10.1152/Ajpcell.2000.278.2.C235  0.548
1999 Bradley KK, Jaggar JH, Bonev AD, Heppner TJ, Flynn ER, Nelson MT, Horowitz B. Kir2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells. The Journal of Physiology. 515: 639-51. PMID 10066894 DOI: 10.1111/J.1469-7793.1999.639Ab.X  0.382
1998 Jaggar JH, Mawe GM, Nelson MT. Voltage-dependent Kcurrents in smooth muscle cells from mouse gallbladder. American Journal of Physiology. Gastrointestinal and Liver Physiology. 274: G687-G693. PMID 29585284 DOI: 10.1152/ajpgi.1998.274.4.G687  0.347
1998 Jaggar JH, Wellman GC, Heppner TJ, Porter VA, Perez GJ, Gollasch M, Kleppisch T, Rubart M, Stevenson AS, Lederer WJ, Knot HJ, Bonev AD, Nelson MT. Ca2+ channels, ryanodine receptors and Ca(2+)-activated K+ channels: a functional unit for regulating arterial tone. Acta Physiologica Scandinavica. 164: 577-87. PMID 9887980 DOI: 10.1046/J.1365-201X.1998.00462.X  0.639
1998 Gollasch M, Wellman GC, Knot HJ, Jaggar JH, Damon DH, Bonev AD, Nelson MT. Ontogeny of local sarcoplasmic reticulum Ca2+ signals in cerebral arteries: Ca2+ sparks as elementary physiological events. Circulation Research. 83: 1104-14. PMID 9831705 DOI: 10.1161/01.Res.83.11.1104  0.6
1998 Jaggar JH, Stevenson AS, Nelson MT. Voltage dependence of Ca2+ sparks in intact cerebral arteries. The American Journal of Physiology. 274: C1755-61. PMID 9611142 DOI: 10.1152/Ajpcell.1998.274.6.C1755  0.543
1998 Jaggar JH, Mawe GM, Nelson MT. Voltage-dependent K+ currents in smooth muscle cells from mouse gallbladder. The American Journal of Physiology. 274: G687-93. PMID 9575850 DOI: 10.1152/Ajpgi.1998.274.4.G687  0.41
1997 Bonev AD, Jaggar JH, Rubart M, Nelson MT. Activators of protein kinase C decrease Ca2+ spark frequency in smooth muscle cells from cerebral arteries. The American Journal of Physiology. 273: C2090-5. PMID 9435516 DOI: 10.1152/Ajpcell.1997.273.6.C2090  0.587
1994 Harding EA, Jaggar JH, Squires PE, Dunne MJ. Polymyxin B has multiple blocking actions on the ATP-sensitive potassium channel in insulin-secreting cells. Pflugers Archiv : European Journal of Physiology. 426: 31-9. PMID 8146022 DOI: 10.1007/Bf00374667  0.424
1994 Jaggar JH, Harding EA, Ayton BA, Dunne MJ. Activation of potassium channels by diazoxide and cromakalim in insulin-secreting cells is dependent upon internal ADP and channel run-down. Biochemical Society Transactions. 21: 426S. PMID 8131997 DOI: 10.1042/bst021426s  0.305
1993 Jaggar JH, Harding EA, Ayton BJ, Dunne MJ. Interaction of diazoxide and cromakalim with ATP-regulated K+ channels in rodent and clonal insulin-secreting cells. Journal of Molecular Endocrinology. 10: 59-70. PMID 8452640 DOI: 10.1677/jme.0.0100059  0.305
1993 Harding EA, Jaggar JH, Ayton BJ, Dunne MJ. Properties of diazoxide and cromakalim-induced activation of potassium channels in cultured rat and RINm5F insulin-secreting cells; effects of GTP. Experimental Physiology. 78: 25-34. PMID 8448011 DOI: 10.1113/expphysiol.1993.sp003668  0.336
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