| Year |
Citation |
Score |
| 2024 |
Taylor R, Basaly V, Kong B, Yang I, Brinker AM, Capece G, Bhattacharya A, Henry ZR, Otersen K, Yang Z, Meadows V, Mera S, Joseph LB, Zhou P, Aleksunes LM, ... ... Guo GL, et al. Effects of Therapeutically Approved Individual Bile Acids on The Development of Metabolic Dysfunction-Associated Steatohepatitis a Low Bile Acid Mouse Model. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 39302723 DOI: 10.1093/toxsci/kfae110 |
0.355 |
|
| 2024 |
Jin J, Nguyen LTG, Wassef A, Sadek R, Schmitt TM, Guo GL, Rasmussen TP, Zhong XB. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 39168525 DOI: 10.1124/dmd.124.001873 |
0.336 |
|
| 2024 |
Jin J, Nguyen LTG, Wassef A, Sadek R, Schmitt TM, Guo GL, Rasmussen TP, Zhong XB. Identification and Functional Characterization of Alternative Transcripts of LncRNA HNF1A-AS1 and Their Impacts on Cell Growth, Differentiation, Liver Diseases, and in Response to Drug Induction. Non-Coding Rna. 10. PMID 38668386 DOI: 10.3390/ncrna10020028 |
0.313 |
|
| 2024 |
Taylor R, Yang Z, Henry Z, Capece G, Meadows V, Otersen K, Basaly V, Bhattacharya A, Mera S, Zhou P, Joseph L, Yang I, Brinker A, Buckley B, Kong B, ... Guo GL, et al. Characterization of individual bile acids in vivo utilizing a novel low bile acid mouse model. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 38526215 DOI: 10.1093/toxsci/kfae029 |
0.336 |
|
| 2024 |
Yang X, Wang J, Chang CY, Zhou F, Liu J, Xu H, Ibrahim M, Gomez M, Guo GL, Liu H, Zong WX, Wondisford FE, Su X, White E, Feng Z, et al. Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice. Nature Communications. 15: 627. PMID 38245529 DOI: 10.1038/s41467-024-44924-w |
0.402 |
|
| 2023 |
Bhattacharya A, Taylor RE, Guo GL. In vivo mouse models to study bile acid synthesis and signaling. Hepatobiliary & Pancreatic Diseases International : Hbpd Int. PMID 37620226 DOI: 10.1016/j.hbpd.2023.08.009 |
0.357 |
|
| 2023 |
Meadows V, Yang Z, Basaly V, Guo GL. FXR Friend-ChIPs in the Enterohepatic System. Seminars in Liver Disease. PMID 37442156 DOI: 10.1055/a-2128-5538 |
0.335 |
|
| 2023 |
Henry Z, Meadows V, Guo GL. FXR and NASH: an avenue for tissue-specific regulation. Hepatology Communications. 7. PMID 37058105 DOI: 10.1097/HC9.0000000000000127 |
0.371 |
|
| 2022 |
Taylor R, Armstrong L, Bhattacharya A, Henry Z, Brinker A, Buckley B, Kong B, Guo G. Myclobutanil Mediated Alteration of Liver-Gut FXR Signaling in Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 36511616 DOI: 10.1093/toxsci/kfac129 |
0.443 |
|
| 2022 |
Guzman S, Dragan M, Kwon H, de Oliveira V, Rao S, Bhatt V, Kalemba KM, Shah A, Rustgi VK, Wang H, Bech PR, Abbara A, Izzi-Engbeaya C, Manousou P, Guo JY, ... Guo GL, et al. Targeting hepatic kisspeptin receptor ameliorates non-alcoholic fatty liver disease in a mouse model. The Journal of Clinical Investigation. PMID 35349482 DOI: 10.1172/JCI145889 |
0.401 |
|
| 2021 |
Rizzolo D, Kong B, Taylor RE, Brinker A, Goedken M, Buckley B, Guo GL. Bile acid homeostasis in female mice deficient in and . Acta Pharmaceutica Sinica. B. 11: 3847-3856. PMID 35024311 DOI: 10.1016/j.apsb.2021.05.023 |
0.366 |
|
| 2021 |
Rizzolo D, Kong B, Piekos S, Chen L, Zhong XB, Lu J, Shi J, Zhu HJ, Yang Q, Li AP, Li L, Wang H, Siemiątkowska A, Park C, Kagan L, ... Guo GL, et al. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34965924 DOI: 10.1124/dmd.121.000416 |
0.36 |
|
| 2021 |
Taylor RE, Bhattacharya A, Guo GL. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34759011 DOI: 10.1124/dmd.121.000388 |
0.377 |
|
| 2020 |
Sun R, Kong B, Yang N, Cao B, Feng D, Yu X, Ge C, Feng S, Fei F, Huang J, Lu Z, Xie Y, Yang CS, Guo GL, Wang G, et al. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal FXR Signaling Pathway and Inhibition of Hepatic Gluconeogenesis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 33376148 DOI: 10.1124/dmd.120.000215 |
0.348 |
|
| 2020 |
Kim YC, Seok S, Zhang Y, Ma J, Kong B, Guo G, Kemper B, Kemper JK. Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A. Nature Communications. 11: 5969. PMID 33235221 DOI: 10.1038/s41467-020-19803-9 |
0.348 |
|
| 2020 |
Yan S, Khambu B, Chen X, Dong Z, Guo G, Yin XM. Hepatic autophagy deficiency remodels gut microbiota for an adaptive protection via FGF15-FGFR4 signaling. Cellular and Molecular Gastroenterology and Hepatology. PMID 33127558 DOI: 10.1016/j.jcmgh.2020.10.011 |
0.347 |
|
| 2020 |
Stofan M, Guo GL. Bile Acids and FXR: Novel Targets for Liver Diseases. Frontiers in Medicine. 7: 544. PMID 33015098 DOI: 10.3389/fmed.2020.00544 |
0.381 |
|
| 2020 |
Huang M, Kong B, Zhang M, Rizzolo D, Armstrong LE, Schumacher JD, Chow MD, Lee YH, Joseph LB, Stofan M, Zhang L, Guo GL. Enhanced alcoholic liver disease in mice with intestine-specific farnesoid X receptor deficiency. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 32404932 DOI: 10.1038/s41374-020-0439-y |
0.412 |
|
| 2020 |
Ferrucci-Da Silva C, Zhan L, Shen J, Kong B, Campbell MJ, Memon N, Hegyi T, Lu L, Guo GL. Effects of total parenteral nutrition on drug metabolism gene expression in mice. Acta Pharmaceutica Sinica. B. 10: 153-158. PMID 31993312 DOI: 10.1016/j.apsb.2019.10.012 |
0.317 |
|
| 2019 |
Nikonorova IA, Zhu Q, Signore CC, Mirek ET, Jonsson WO, Kong B, Guo GL, Belden WJ, Anthony TG. Age modulates liver responses to asparaginase-induced amino acid stress in mice. The Journal of Biological Chemistry. PMID 31413113 DOI: 10.1074/jbc.RA119.009864 |
0.384 |
|
| 2019 |
Schumacher JD, Kong B, Wu J, Rizzolo D, Armstrong LE, Chow MD, Goedken M, Lee YH, Guo GL. Direct and Indirect Effects of FGF15 and FGF19 on Liver Fibrosis Development. Hepatology (Baltimore, Md.). PMID 31206730 DOI: 10.1002/hep.30810 |
0.405 |
|
| 2019 |
Byun S, Jung H, Chen J, Kim YC, Kim DH, Kong B, Guo G, Kemper B, Kemper JK. Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis. The Journal of Biological Chemistry. PMID 30996006 DOI: 10.1074/Jbc.Ra119.008360 |
0.402 |
|
| 2019 |
Dong B, Singh AB, Guo GL, Young M, Liu J. Activation of FXR by obeticholic acid induces hepatic gene expression of SR-BI through a novel mechanism of transcriptional synergy with the nuclear receptor LXR. International Journal of Molecular Medicine. PMID 30896855 DOI: 10.3892/ijmm.2019.4136 |
0.387 |
|
| 2019 |
Rizzolo D, Buckley K, Kong B, Zhan L, Shen J, Stofan M, Brinker A, Goedken M, Buckley B, Guo GL. Bile acid homeostasis in a Cyp7a1 & Cyp27a1 double knockout mouse model. Hepatology (Baltimore, Md.). PMID 30864232 DOI: 10.1002/Hep.30612 |
0.416 |
|
| 2019 |
Kong B, Zhang M, Huang M, Rizzolo D, Armstrong LE, Schumacher JD, Chow MD, Lee YH, Guo GL. FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 30803859 DOI: 10.1016/j.dld.2018.12.026 |
0.37 |
|
| 2018 |
Kim YC, Byun S, Seok S, Guo G, Xu HE, Kemper B, Kemper JK. Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption. Gastroenterology. PMID 30521806 DOI: 10.1053/J.Gastro.2018.11.061 |
0.354 |
|
| 2018 |
Memon N, Griffin IJ, Lee CW, Herdt A, Weinberger BI, Hegyi T, Carayannopoulos MO, Aleksunes LM, Guo GL. Developmental regulation of the gut-liver (FGF19-CYP7A1) axis in neonates. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 1-181. PMID 30122083 DOI: 10.1080/14767058.2018.1513483 |
0.317 |
|
| 2018 |
Kong B, Guo GL. Is this the time to reconsider the names for xenobiotic nuclear receptors? Hepatology (Baltimore, Md.). PMID 30113075 DOI: 10.1002/hep.30218 |
0.418 |
|
| 2018 |
Byun S, Kim DH, Ryerson D, Kim YC, Sun H, Kong B, Yau P, Guo G, Xu HE, Kemper B, Kemper JK. Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis. Nature Communications. 9: 2590. PMID 29968724 DOI: 10.1038/S41467-018-04697-5 |
0.356 |
|
| 2018 |
Wang P, Sachar M, Guo GL, Shehu AI, Lu J, Zhong XB, Ma X. Liver Metabolomics in a Mouse Model of Erythropoietic Protoporphyria. Biochemical Pharmacology. PMID 29906468 DOI: 10.1016/j.bcp.2018.06.011 |
0.4 |
|
| 2018 |
Zhang M, Kong B, Huang M, Wan R, Armstrong LE, Schumacher JD, Rizzolo D, Chow MD, Lee YH, Guo GL. FXR deletion in hepatocytes does not affect the severity of alcoholic liver disease in mice. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 29730159 DOI: 10.1016/j.dld.2018.04.009 |
0.377 |
|
| 2018 |
Kong B, Sun R, Huang M, Chow MD, Zhong XB, Xie W, Lee YH, Guo GL. A Novel Fibroblast Growth Factor 15 Dependent- and Bile Acid Independent-Promotion of Liver Regeneration in Mice. Hepatology (Baltimore, Md.). PMID 29672888 DOI: 10.1002/hep.30041 |
0.357 |
|
| 2018 |
Liu X, Guo GL, Kong B, Hilburn DB, Hubchak SC, Park S, LeCuyer B, Hsieh A, Wang L, Fang D, Green RM. Farnesoid X Receptor Signaling Activates the Hepatic X-box Binding Protein 1 Pathway in vitro and in Mice. Hepatology (Baltimore, Md.). PMID 29377207 DOI: 10.1002/Hep.29815 |
0.405 |
|
| 2017 |
Peng L, Piekos SC, Guo GL, Zhong XB. Role of Farnesoid X Receptor in the Determination of Liver Transcriptome during Postnatal Maturation in Mice. Nuclear Receptor Research. 4. PMID 29795774 DOI: 10.11131/2017/101308 |
0.412 |
|
| 2017 |
Huang M, Williams J, Kong B, Zhu Y, Li G, Zhu Z, Guo GL. Fibroblast growth factor 15 deficiency increases susceptibility but does not improve repair to acetaminophen-induced liver injury in mice. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 28867475 DOI: 10.1016/j.dld.2017.08.023 |
0.366 |
|
| 2017 |
Chow MD, Lee YH, Guo GL. The role of bile acids in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Molecular Aspects of Medicine. PMID 28442273 DOI: 10.1016/j.mam.2017.04.004 |
0.329 |
|
| 2017 |
Moscovitz JE, Yarmush G, Herrera-Garcia G, Guo GL, Aleksunes LM. Differential regulation of intestinal efflux transporters by pregnancy in mice. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-9. PMID 28043194 DOI: 10.1080/00498254.2016.1250292 |
0.365 |
|
| 2016 |
Niu Y, Xu M, Slagle BL, Huang H, Li S, Guo GL, Shi G, Qin W, Xie W. Farnesoid X receptor ablation sensitizes mice to hepatitis b virus X protein-induced hepatocarcinogenesis. Hepatology (Baltimore, Md.). PMID 28102638 DOI: 10.1002/Hep.28924 |
0.314 |
|
| 2016 |
Sun R, Yang N, Kong B, Cao B, Feng D, Yu X, Ge C, Huang J, Shen J, Wang P, Feng S, Fei F, Guo J, He J, Aa N, ... ... Guo GL, et al. Orally administered berberine modulates hepatic lipid metabolism by altering microbial bile acid metabolism and the intestinal FXR signaling pathway. Molecular Pharmacology. PMID 27932556 DOI: 10.1124/mol.116.106617 |
0.347 |
|
| 2016 |
Bright AS, Herrera-Garcia G, Moscovitz JE, You D, Guo GL, Aleksunes LM. Regulation of Drug Disposition Gene Expression in Pregnant Mice with Car Receptor Activation. Nuclear Receptor Research. 3. PMID 27818994 DOI: 10.11131/2016/101193 |
0.324 |
|
| 2016 |
Peng L, Piekos S, Guo GL, Zhong XB. Role of farnesoid X receptor in establishment of ontogeny of phase-I drug metabolizing enzyme genes in mouse liver. Acta Pharmaceutica Sinica. B. 6: 453-459. PMID 27709014 DOI: 10.1016/j.apsb.2016.07.015 |
0.328 |
|
| 2016 |
Zhu Y, Liu H, Zhang M, Guo GL. Fatty liver diseases, bile acids, and FXR. Acta Pharmaceutica Sinica. B. 6: 409-412. PMID 27709009 DOI: 10.1016/j.apsb.2016.07.008 |
0.365 |
|
| 2016 |
Moscovitz JE, Kong B, Buckley K, Buckley B, Guo GL, Aleksunes LM. Restoration of enterohepatic bile acid pathways in pregnant mice following short term activation of Fxr by GW4064. Toxicology and Applied Pharmacology. PMID 27609522 DOI: 10.1016/J.Taap.2016.08.021 |
0.383 |
|
| 2016 |
Kong B, Zhu Y, Li G, Williams JA, Buckley K, Tawfik O, Luyendyk JP, Guo GL. Mice with Hepatocyte-Specific FXR Deficiency are Resistant to Spontaneous but Susceptible to Cholic Acid Induced Hepatocarcinogenesis. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00134.2015. PMID 26744468 DOI: 10.1152/ajpgi.00134.2015 |
0.365 |
|
| 2015 |
Zhan L, Yang I, Kong B, Shen J, Gorczyca L, Memon N, Buckley BT, Guo GL. Dysregulation of bile acid homeostasis in parenteral nutrition mouse model. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00252.2015. PMID 26564717 DOI: 10.1152/Ajpgi.00252.2015 |
0.453 |
|
| 2015 |
Cheng Q, Inaba Y, Lu P, Xu M, He J, Zhao Y, Guo GL, Kuruba R, de la Vega R, Evans RW, Li S, Xie W. Chronic activation of FXR in transgenic mice caused perinatal toxicity and sensitized mice to cholesterol toxicity. Molecular Endocrinology (Baltimore, Md.). 29: 571-82. PMID 25719402 DOI: 10.1210/Me.2014-1337 |
0.457 |
|
| 2015 |
Tsuchiya H, da Costa KA, Lee S, Renga B, Jaeschke H, Yang Z, Orena SJ, Goedken MJ, Zhang Y, Kong B, Lebofsky M, Rudraiah S, Smalling R, Guo G, Fiorucci S, et al. Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice. Gastroenterology. 148: 1012-1023.e14. PMID 25701738 DOI: 10.1053/j.gastro.2015.01.045 |
0.374 |
|
| 2015 |
Oshida K, Vasani N, Thomas RS, Applegate D, Rosen M, Abbott B, Lau C, Guo G, Aleksunes LM, Klaassen C, Corton JC. Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium. Plos One. 10: e0112655. PMID 25689681 DOI: 10.1371/Journal.Pone.0112655 |
0.376 |
|
| 2015 |
Schmitt J, Kong B, Stieger B, Tschopp O, Schultze SM, Rau M, Weber A, Müllhaupt B, Guo GL, Geier A. Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal. Liver International : Official Journal of the International Association For the Study of the Liver. 35: 1133-44. PMID 25156247 DOI: 10.1111/liv.12456 |
0.381 |
|
| 2014 |
Manley S, Ni HM, Williams JA, Kong B, DiTacchio L, Guo G, Ding WX. Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity. Redox Biology. 2: 991-1002. PMID 25460735 DOI: 10.1016/J.Redox.2014.08.007 |
0.441 |
|
| 2014 |
Zhan L, Liu HX, Fang Y, Kong B, He Y, Zhong XB, Fang J, Wan YJ, Guo GL. Genome-wide binding and transcriptome analysis of human farnesoid X receptor in primary human hepatocytes. Plos One. 9: e105930. PMID 25198545 DOI: 10.1371/Journal.Pone.0105930 |
0.522 |
|
| 2014 |
Kong B, Huang J, Zhu Y, Li G, Williams J, Shen S, Aleksunes LM, Richardson JR, Apte U, Rudnick DA, Guo GL. Fibroblast growth factor 15 deficiency impairs liver regeneration in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G893-902. PMID 24699334 DOI: 10.1152/Ajpgi.00337.2013 |
0.402 |
|
| 2014 |
Zhang Y, Xu N, Xu J, Kong B, Copple B, Guo GL, Wang L. E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network. Hepatology (Baltimore, Md.). 60: 919-30. PMID 24619556 DOI: 10.1002/hep.27121 |
0.468 |
|
| 2014 |
Manley S, Ni HM, Kong B, Apte U, Guo G, Ding WX. Suppression of autophagic flux by bile acids in hepatocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 478-90. PMID 24189133 DOI: 10.1093/Toxsci/Kft246 |
0.523 |
|
| 2013 |
Li G, Zhu Y, Tawfik O, Kong B, Williams JA, Zhan L, Kassel KM, Luyendyk JP, Wang L, Guo GL. Mechanisms of STAT3 activation in the liver of FXR knockout mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G829-37. PMID 24091600 DOI: 10.1152/ajpgi.00155.2013 |
0.426 |
|
| 2013 |
Jiang Y, Jin J, Iakova P, Hernandez JC, Jawanmardi N, Sullivan E, Guo GL, Timchenko NA, Darlington GJ. Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice. Mechanisms of Ageing and Development. 134: 407-15. PMID 24007921 DOI: 10.1016/j.mad.2013.08.003 |
0.431 |
|
| 2013 |
He Y, Gong L, Fang Y, Zhan Q, Liu HX, Lu Y, Guo GL, Lehman-McKeeman L, Fang J, Wan YJ. The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling. Bmc Genomics. 14: 575. PMID 23981290 DOI: 10.1186/1471-2164-14-575 |
0.351 |
|
| 2013 |
Li G, Kong B, Zhu Y, Zhan L, Williams JA, Tawfik O, Kassel KM, Luyendyk JP, Wang L, Guo GL. Small heterodimer partner overexpression partially protects against liver tumor development in farnesoid X receptor knockout mice. Toxicology and Applied Pharmacology. 272: 299-305. PMID 23811326 DOI: 10.1016/j.taap.2013.06.016 |
0.415 |
|
| 2013 |
Thomas AM, Hart SN, Li G, Lu H, Fang Y, Fang J, Zhong XB, Guo GL. Hepatocyte nuclear factor 4 alpha and farnesoid X receptor co-regulates gene transcription in mouse livers on a genome-wide scale. Pharmaceutical Research. 30: 2188-98. PMID 23462932 DOI: 10.1007/S11095-013-1006-7 |
0.408 |
|
| 2013 |
Zhu Y, Li G, Dong Y, Zhou HH, Kong B, Aleksunes LM, Richardson JR, Li F, Guo GL. Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver. Toxicology and Applied Pharmacology. 266: 260-6. PMID 23178280 DOI: 10.1016/j.taap.2012.11.012 |
0.434 |
|
| 2012 |
Williams JA, Thomas AM, Li G, Kong B, Zhan L, Inaba Y, Xie W, Ding WX, Guo GL. Tissue specific induction of p62/Sqstm1 by farnesoid X receptor. Plos One. 7: e43961. PMID 22952826 DOI: 10.1371/Journal.Pone.0043961 |
0.485 |
|
| 2012 |
Borude P, Edwards G, Walesky C, Li F, Ma X, Kong B, Guo GL, Apte U. Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice. Hepatology (Baltimore, Md.). 56: 2344-52. PMID 22730081 DOI: 10.1002/Hep.25918 |
0.532 |
|
| 2012 |
Li G, Thomas AM, Williams JA, Kong B, Liu J, Inaba Y, Xie W, Guo GL. Farnesoid X receptor induces murine scavenger receptor Class B type I via intron binding. Plos One. 7: e35895. PMID 22540009 DOI: 10.1371/Journal.Pone.0035895 |
0.552 |
|
| 2012 |
Kong B, Csanaky IL, Aleksunes LM, Patni M, Chen Q, Ma X, Jaeschke H, Weir S, Broward M, Klaassen CD, Guo GL. Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity. Toxicology and Applied Pharmacology. 261: 189-95. PMID 22521610 DOI: 10.1016/J.Taap.2012.04.001 |
0.457 |
|
| 2012 |
Kong B, Wang L, Chiang JY, Zhang Y, Klaassen CD, Guo GL. Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice. Hepatology (Baltimore, Md.). 56: 1034-43. PMID 22467244 DOI: 10.1002/Hep.25740 |
0.491 |
|
| 2012 |
Cui JY, Aleksunes LM, Tanaka Y, Fu ZD, Guo Y, Guo GL, Lu H, Zhong XB, Klaassen CD. Bile acids via FXR initiate the expression of major transporters involved in the enterohepatic circulation of bile acids in newborn mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G979-96. PMID 22268101 DOI: 10.1152/Ajpgi.00370.2011 |
0.526 |
|
| 2012 |
Li G, Lin W, Araya JJ, Chen T, Timmermann BN, Guo GL. A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor. Toxicology and Applied Pharmacology. 258: 268-74. PMID 22178739 DOI: 10.1016/J.Taap.2011.11.006 |
0.479 |
|
| 2011 |
Kassel KM, Owens AP, Rockwell CE, Sullivan BP, Wang R, Tawfik O, Li G, Guo GL, Mackman N, Luyendyk JP. Protease-activated receptor 1 and hematopoietic cell tissue factor are required for hepatic steatosis in mice fed a Western diet. The American Journal of Pathology. 179: 2278-89. PMID 21907177 DOI: 10.1016/J.Ajpath.2011.07.015 |
0.495 |
|
| 2011 |
Pacyniak E, Hagenbuch B, Klaassen CD, Lehman-McKeeman L, Guo GL. Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice. Toxicology and Applied Pharmacology. 257: 23-31. PMID 21884716 DOI: 10.1016/J.Taap.2011.08.014 |
0.688 |
|
| 2011 |
Luyendyk JP, Guo GL. Steatosis DeLIVERs high-sensitivity C-reactive protein. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1714-5. PMID 21775769 DOI: 10.1161/Atvbaha.111.230722 |
0.413 |
|
| 2011 |
Kong B, Guo GL. Enhanced in vitro refolding of fibroblast growth factor 15 with the assistance of SUMO fusion partner. Plos One. 6: e20307. PMID 21655243 DOI: 10.1371/Journal.Pone.0020307 |
0.309 |
|
| 2011 |
Li G, Guo GL. Role of Class II nuclear receptors in liver carcinogenesis. Anti-Cancer Agents in Medicinal Chemistry. 11: 529-42. PMID 21554208 DOI: 10.2174/187152011796011064 |
0.398 |
|
| 2011 |
Luyendyk JP, Kassel KM, Allen K, Guo GL, Li G, Cantor GH, Copple BL. Fibrinogen deficiency increases liver injury and early growth response-1 (Egr-1) expression in a model of chronic xenobiotic-induced cholestasis. The American Journal of Pathology. 178: 1117-25. PMID 21356363 DOI: 10.1016/J.Ajpath.2010.11.064 |
0.492 |
|
| 2011 |
Zhang YK, Guo GL, Klaassen CD. Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters. Plos One. 6: e16683. PMID 21346810 DOI: 10.1371/Journal.Pone.0016683 |
0.371 |
|
| 2011 |
Li T, Matozel M, Boehme S, Kong B, Nilsson LM, Guo G, Ellis E, Chiang JY. Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis. Hepatology (Baltimore, Md.). 53: 996-1006. PMID 21319191 DOI: 10.1002/Hep.24107 |
0.485 |
|
| 2011 |
Zhu Y, Li F, Guo GL. Tissue-specific function of farnesoid X receptor in liver and intestine. Pharmacological Research. 63: 259-65. PMID 21211565 DOI: 10.1016/J.Phrs.2010.12.018 |
0.486 |
|
| 2010 |
Weaver BP, Zhang Y, Hiscox S, Guo GL, Apte U, Taylor KM, Sheline CT, Wang L, Andrews GK. Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration. Plos One. 5. PMID 20957146 DOI: 10.1371/Journal.Pone.0013158 |
0.406 |
|
| 2010 |
Wang L, Li F, Lu J, Li G, Li D, Zhong XB, Guo GL, Ma X. The Chinese herbal medicine Sophora flavescens activates pregnane X receptor. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2226-31. PMID 20736322 DOI: 10.1124/dmd.110.035253 |
0.322 |
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| 2010 |
Kassel KM, Guo GL, Tawfik O, Luyendyk JP. Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1794-804. PMID 20697377 DOI: 10.1038/Labinvest.2010.143 |
0.447 |
|
| 2010 |
Li G, Thomas AM, Hart SN, Zhong X, Wu D, Guo GL. Farnesoid X receptor activation mediates head-to-tail chromatin looping in the Nr0b2 gene encoding small heterodimer partner. Molecular Endocrinology (Baltimore, Md.). 24: 1404-12. PMID 20444884 DOI: 10.1210/Me.2010-0014 |
0.425 |
|
| 2010 |
Pacyniak E, Roth M, Hagenbuch B, Guo GL. Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 344-53. PMID 20176623 DOI: 10.1093/Toxsci/Kfq059 |
0.654 |
|
| 2010 |
Thomas AM, Hart SN, Kong B, Fang J, Zhong XB, Guo GL. Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine. Hepatology (Baltimore, Md.). 51: 1410-9. PMID 20091679 DOI: 10.1002/Hep.23450 |
0.492 |
|
| 2010 |
Luyendyk JP, Sullivan BP, Guo GL, Wang R. Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice. The American Journal of Pathology. 176: 177-86. PMID 20008134 DOI: 10.2353/Ajpath.2010.090672 |
0.504 |
|
| 2009 |
Maran RR, Thomas A, Roth M, Sheng Z, Esterly N, Pinson D, Gao X, Zhang Y, Ganapathy V, Gonzalez FJ, Guo GL. Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development. The Journal of Pharmacology and Experimental Therapeutics. 328: 469-77. PMID 18981289 DOI: 10.1124/Jpet.108.145409 |
0.447 |
|
| 2009 |
Kong B, Luyendyk JP, Tawfik O, Guo GL. Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet. The Journal of Pharmacology and Experimental Therapeutics. 328: 116-22. PMID 18948497 DOI: 10.1124/Jpet.108.144600 |
0.443 |
|
| 2008 |
Tanaka Y, Aleksunes LM, Yeager RL, Gyamfi MA, Esterly N, Guo GL, Klaassen CD. NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet. The Journal of Pharmacology and Experimental Therapeutics. 325: 655-64. PMID 18281592 DOI: 10.1124/Jpet.107.135822 |
0.47 |
|
| 2007 |
Kim I, Ahn SH, Inagaki T, Choi M, Ito S, Guo GL, Kliewer SA, Gonzalez FJ. Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine. Journal of Lipid Research. 48: 2664-72. PMID 17720959 DOI: 10.1194/Jlr.M700330-Jlr200 |
0.435 |
|
| 2007 |
Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, Dalton TP, Yamamoto M, Klaassen CD. Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology (Baltimore, Md.). 46: 1597-610. PMID 17668877 DOI: 10.1002/Hep.21831 |
0.467 |
|
| 2007 |
Ma X, Shah YM, Guo GL, Wang T, Krausz KW, Idle JR, Gonzalez FJ. Rifaximin is a gut-specific human pregnane X receptor activator. The Journal of Pharmacology and Experimental Therapeutics. 322: 391-8. PMID 17442842 DOI: 10.1124/Jpet.107.121913 |
0.488 |
|
| 2007 |
Pacyniak EK, Cheng X, Cunningham ML, Crofton K, Klaassen CD, Guo GL. The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 94-102. PMID 17324954 DOI: 10.1093/Toxsci/Kfm025 |
0.669 |
|
| 2007 |
Ma X, Shah Y, Cheung C, Guo GL, Feigenbaum L, Krausz KW, Idle JR, Gonzalez FJ. The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 194-200. PMID 17093002 DOI: 10.1124/Dmd.106.012831 |
0.419 |
|
| 2006 |
Guo GL, Santamarina-Fojo S, Akiyama TE, Amar MJ, Paigen BJ, Brewer B, Gonzalez FJ. Effects of FXR in foam-cell formation and atherosclerosis development. Biochimica Et Biophysica Acta. 1761: 1401-9. PMID 17110163 DOI: 10.1016/j.bbalip.2006.09.018 |
0.312 |
|
| 2006 |
Nakamoto K, Wang S, Jenison RD, Guo GL, Klaassen CD, Wan YJ, Zhong XB. Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene. Bmc Genetics. 7: 29. PMID 16709249 DOI: 10.1186/1471-2156-7-29 |
0.309 |
|
| 2006 |
Yamamoto Y, Moore R, Hess HA, Guo GL, Gonzalez FJ, Korach KS, Maronpot RR, Negishi M. Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity. The Journal of Biological Chemistry. 281: 16625-31. PMID 16606610 DOI: 10.1074/jbc.M602723200 |
0.422 |
|
| 2005 |
Jia Y, Guo GL, Surapureddi S, Sarkar J, Qi C, Guo D, Xia J, Kashireddi P, Yu S, Cho YW, Rao MS, Kemper B, Ge K, Gonzalez FJ, Reddy JK. Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 102: 12531-6. PMID 16109766 DOI: 10.1073/Pnas.0506000102 |
0.421 |
|
| 2004 |
Guo GL, Moffit JS, Nicol CJ, Ward JM, Aleksunes LA, Slitt AL, Kliewer SA, Manautou JE, Gonzalez FJ. Enhanced acetaminophen toxicity by activation of the pregnane X receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 82: 374-80. PMID 15456926 DOI: 10.1093/Toxsci/Kfh286 |
0.425 |
|
| 2003 |
Wagner M, Fickert P, Zollner G, Fuchsbichler A, Silbert D, Tsybrovskyy O, Zatloukal K, Guo GL, Schuetz JD, Gonzalez FJ, Marschall HU, Denk H, Trauner M. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. Gastroenterology. 125: 825-38. PMID 12949728 DOI: 10.1016/S0016-5085(03)01068-0 |
0.43 |
|
| 2003 |
Kitada H, Miyata M, Nakamura T, Tozawa A, Honma W, Shimada M, Nagata K, Sinal CJ, Guo GL, Gonzalez FJ, Yamazoe Y. Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity. The Journal of Biological Chemistry. 278: 17838-44. PMID 12637555 DOI: 10.1074/jbc.M210634200 |
0.445 |
|
| 2002 |
Lambert G, Amar MJ, Guo G, Brewer HB, Gonzalez FJ, Sinal CJ. The farnesoid X-receptor is an essential regulator of cholesterol homeostasis. The Journal of Biological Chemistry. 278: 2563-70. PMID 12421815 DOI: 10.1074/JBC.M209525200 |
0.312 |
|
| 2002 |
Guo GL, Staudinger J, Ogura K, Klaassen CD. Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16alpha-carbonitrile is via interaction with pregnane X receptor. Molecular Pharmacology. 61: 832-9. PMID 11901222 DOI: 10.1124/Mol.61.4.832 |
0.389 |
|
| 2002 |
Guo GL, Johnson DR, Klaassen CD. Postnatal expression and induction by pregnenolone-16alpha-carbonitrile of the organic anion-transporting polypeptide 2 in rat liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 283-8. PMID 11854146 DOI: 10.1124/Dmd.30.3.283 |
0.391 |
|
| 2002 |
Guo GL, Choudhuri S, Klaassen CD. Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways. The Journal of Pharmacology and Experimental Therapeutics. 300: 206-12. PMID 11752118 DOI: 10.1124/Jpet.300.1.206 |
0.424 |
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