Year |
Citation |
Score |
2022 |
Sugitani N, Vendetti FP, Cipriano AJ, Pandya P, Deppas JJ, Moiseeva TN, Schamus-Haynes S, Wang Y, Palmer D, Osmanbeyoglu HU, Bostwick A, Snyder NW, Gong YN, Aird KM, Delgoffe GM, ... ... Bakkenist CJ, et al. Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression. Cell Reports. 40: 111371. PMID 36130512 DOI: 10.1016/j.celrep.2022.111371 |
0.364 |
|
2022 |
Kiesel BF, Deppas JJ, Guo J, Parise RA, Clump DA, Bakkenist CJ, Beumer JH. Dose-dependent bioavailability, absorption-rate limited elimination, and tissue distribution of the ATR inhibitor BAY-1895344 (elimusertib) in mice. Cancer Chemotherapy and Pharmacology. PMID 35507041 DOI: 10.1007/s00280-022-04436-0 |
0.333 |
|
2019 |
Moiseeva TN, Qian C, Sugitani N, Osmanbeyoglu HU, Bakkenist CJ. WEE1 kinase inhibitor AZD1775 induces CDK1 kinase-dependent origin firing in unperturbed G1- and S-phase cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31712441 DOI: 10.1073/Pnas.1915108116 |
0.483 |
|
2019 |
Martino J, Brunette GJ, Barroso-González J, Moiseeva TN, Smith CM, Bakkenist CJ, O'Sullivan RJ, Bernstein KA. The human Shu complex functions with PDS5B and SPIDR to promote homologous recombination. Nucleic Acids Research. 47: 10151-10165. PMID 31665741 DOI: 10.1093/Nar/Gkz738 |
0.431 |
|
2019 |
Leonard BC, Lee ED, Bhola NE, Li H, Sogaard KK, Bakkenist CJ, Grandis JR, Johnson DE. ATR inhibition sensitizes HPV and HPV head and neck squamous cell carcinoma to cisplatin. Oral Oncology. 95: 35-42. PMID 31345392 DOI: 10.1016/J.Oraloncology.2019.05.028 |
0.422 |
|
2019 |
Moiseeva TN, Bakkenist CJ. Dormant origin signaling during unperturbed replication. Dna Repair. 102655. PMID 31311769 DOI: 10.1016/J.Dnarep.2019.102655 |
0.55 |
|
2019 |
Moiseeva TN, Yin Y, Calderon MJ, Qian C, Schamus-Haynes S, Sugitani N, Osmanbeyoglu HU, Rothenberg E, Watkins SC, Bakkenist CJ. An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication. Proceedings of the National Academy of Sciences of the United States of America. PMID 31209037 DOI: 10.1073/Pnas.1903418116 |
0.55 |
|
2019 |
Bakkenist CJ, Czambel RK, Lin Y, Yates NA, Zeng X, Shogan J, Schmitz JC. Quantitative analysis of ATM phosphorylation in lymphocytes. Dna Repair. 80: 1-7. PMID 31176958 DOI: 10.1016/J.Dnarep.2019.06.002 |
0.437 |
|
2018 |
Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S. Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA. Nature Communications. 9: 5351. PMID 30559436 DOI: 10.1038/S41467-018-07798-3 |
0.545 |
|
2018 |
Bakkenist CJ, Lee JJ, Schmitz JC. ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer. Clinical Colorectal Cancer. PMID 30316683 DOI: 10.1016/J.Clcc.2018.09.001 |
0.419 |
|
2018 |
Moiseeva TN, Bakkenist CJ. Regulation of the initiation of DNA replication in human cells. Dna Repair. PMID 30266203 DOI: 10.1016/J.Dnarep.2018.09.003 |
0.431 |
|
2018 |
Vendetti FP, Karukonda P, Clump DA, Teo T, Lalonde R, Nugent K, Ballew M, Kiesel BF, Beumer JH, Sarkar SN, Conrads TP, O'Connor MJ, Ferris RL, Tran PT, Delgoffe GM, ... Bakkenist CJ, et al. ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation. The Journal of Clinical Investigation. PMID 29952768 DOI: 10.1172/Jci96519 |
0.476 |
|
2018 |
Evdokimova VN, Gandhi M, Nikitski AV, Bakkenist CJ, Nikiforov YE. Nuclear myosin/actin-motored contact between homologous chromosomes is initiated by ATM kinase and homology-directed repair proteins at double-strand DNA breaks to suppress chromosome rearrangements. Oncotarget. 9: 13612-13622. PMID 29568381 DOI: 10.18632/Oncotarget.24434 |
0.457 |
|
2018 |
Bateman N, Ao W, Tommarello D, Conrads K, Teng P, Darcy K, Hamilton C, Maxwell GL, Bakkenist C, Conrads T. Abstract 2852: Identifying circulating biomarkers of acute response and resistance to clinical ATR and Chk1 inhibitors Cancer Research. 78: 2852-2852. DOI: 10.1158/1538-7445.Am2018-2852 |
0.419 |
|
2017 |
Moiseeva T, Hood B, Schamus S, O'Connor MJ, Conrads TP, Bakkenist CJ. ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1. Nature Communications. 8: 1392. PMID 29123096 DOI: 10.1038/S41467-017-01401-X |
0.552 |
|
2017 |
Kiesel BF, Scemama J, Parise RA, Villaruz L, Iffland A, Doyle A, Ivy P, Chu E, Bakkenist CJ, Beumer JH. LC-MS/MS assay for the quantitation of the ATR kinase inhibitor VX-970 in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 146: 244-250. PMID 28888173 DOI: 10.1016/J.Jpba.2017.08.037 |
0.424 |
|
2017 |
Kiesel BF, Shogan JC, Rachid M, Parise RA, Vendetti FP, Bakkenist CJ, Beumer JH. LC-MS/MS assay for the simultaneous quantitation of the ATM inhibitor AZ31 and the ATR inhibitor AZD6738 in mouse plasma. Journal of Pharmaceutical and Biomedical Analysis. 138: 158-165. PMID 28213176 DOI: 10.1016/J.Jpba.2017.01.055 |
0.312 |
|
2017 |
Vendetti FP, Leibowitz BJ, Barnes J, Schamus S, Kiesel BF, Abberbock S, Conrads T, Clump DA, Cadogan E, O'Connor MJ, Yu J, Beumer JH, Bakkenist CJ. Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation. Scientific Reports. 7: 41892. PMID 28145510 DOI: 10.1038/Srep41892 |
0.405 |
|
2017 |
Karukonda P, Vendetti F, Tran P, Clump D, Ferris R, Bakkenist C. ATR Kinase Inhibition Leads to Durable Radiosensitization of the Murine Kras G12D /Twist1 Lung Adenocarcinoma Model via a CD8 + T Cell-Dependent Mechanism International Journal of Radiation Oncology*Biology*Physics. 99: S30-S31. DOI: 10.1016/J.Ijrobp.2017.06.084 |
0.374 |
|
2016 |
Villaruz LC, Jones H, Dacic S, Abberbock S, Kurland BF, Stabile LP, Siegfried JM, Conrads TP, Smith NR, O'Connor MJ, Pierce AJ, Bakkenist CJ. ATM protein is deficient in over 40% of lung adenocarcinomas. Oncotarget. PMID 27259260 DOI: 10.18632/Oncotarget.9757 |
0.38 |
|
2016 |
Moiseeva TN, Gamper AM, Hood BL, Conrads TP, Bakkenist CJ. Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19. Dna Repair. 43: 9-17. PMID 27235625 DOI: 10.1016/J.Dnarep.2016.04.007 |
0.476 |
|
2015 |
Vendetti FP, Lau A, Schamus S, Conrads TP, O'Connor MJ, Bakkenist CJ. The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo. Oncotarget. PMID 26517239 DOI: 10.18632/Oncotarget.6247 |
0.536 |
|
2015 |
Bakkenist CJ, Beumer JH, Schmitz JC. ATM serine-1981 phosphorylation is a plausible biomarker. Cell Cycle (Georgetown, Tex.). 14: 3207-8. PMID 26517194 DOI: 10.1080/15384101.2015.1084205 |
0.448 |
|
2015 |
Beumer JH, Fu KY, Anyang BN, Siegfried JM, Bakkenist CJ. Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma. Bmc Cancer. 15: 649. PMID 26438152 DOI: 10.1186/S12885-015-1649-3 |
0.473 |
|
2015 |
Bakkenist CJ, Kastan MB. Chromatin perturbations during the DNA damage response in higher eukaryotes. Dna Repair. 36: 8-12. PMID 26391293 DOI: 10.1016/J.Dnarep.2015.09.002 |
0.525 |
|
2015 |
Bakkenist CJ, Czambel RK, Hershberger PA, Tawbi H, Beumer JH, Schmitz JC. A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells. Oncoscience. 2: 542-54. PMID 26097887 |
0.468 |
|
2015 |
Teng PN, Bateman NW, Darcy KM, Hamilton CA, Maxwell GL, Bakkenist CJ, Conrads TP. Pharmacologic inhibition of ATR and ATM offers clinically important distinctions to enhancing platinum or radiation response in ovarian, endometrial, and cervical cancer cells. Gynecologic Oncology. 136: 554-61. PMID 25560806 DOI: 10.1016/J.Ygyno.2014.12.035 |
0.424 |
|
2014 |
Forero A, Giacobbi NS, McCormick KD, Gjoerup OV, Bakkenist CJ, Pipas JM, Sarkar SN. Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase. Journal of Immunology (Baltimore, Md. : 1950). 192: 5933-42. PMID 24799566 DOI: 10.4049/Jimmunol.1303470 |
0.405 |
|
2014 |
Teng P, Bateman NW, Hamilton CA, Maxwell GL, Bakkenist CJ, Conrads TP. Abstract 3758: Inhibition of ATR, but not ATM, sensitizes gynecologic cancer cells to cisplatin Cancer Research. 74: 3758-3758. DOI: 10.1158/1538-7445.Am2014-3758 |
0.515 |
|
2014 |
Bateman N, Teng P, Conrads K, Hamilton C, Maxwell G, Bakkenist C, Conrads T. Abstract 2747: Pharmacological inhibition of the DNA damage response kinases, ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated), broadly sensitizes diverse subtypes of gynecological cancer cells to ionizing radiation Cancer Research. 74: 2747-2747. DOI: 10.1158/1538-7445.Am2014-2747 |
0.549 |
|
2014 |
Teng P, Bateman N, Conrads K, Oliver K, Hamilton C, Maxwell G, Bakkenist C, Conrads T. Enhanced gynecologic cancer cell killing through pharmacologic inhibition of the ataxia telangiectasia and Rad3-related kinase Gynecologic Oncology. 133: 108-109. DOI: 10.1016/J.Ygyno.2014.03.289 |
0.355 |
|
2014 |
Bateman N, Teng P, Conrads K, Hamilton C, Maxwell G, Bakkenist C, Conrads T. Pharmacologic inhibition of the DNA damage response kinases ATR (ataxia telangiectasia and rad3 related) and ATM (ataxia telangiectasia mutated) broadly sensitizes diverse subtypes of gynecologic cancer cells to ionizing radiation Gynecologic Oncology. 133: 21. DOI: 10.1016/J.Ygyno.2014.03.072 |
0.445 |
|
2013 |
Uttam S, Bista RK, Staton K, Alexandrov S, Choi S, Bakkenist CJ, Hartman DJ, Brand RE, Liu Y. Erratum: Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation: erratum. Biomedical Optics Express. 4: 2491. PMID 24312743 DOI: 10.1364/BOE.4.002491 |
0.609 |
|
2013 |
Bakkenist CJ, Vaziri C. Stoichiometry of ubiquitin-binding proteins directs DSB repair. Cell Cycle (Georgetown, Tex.). 12: 3716-7. PMID 24189535 DOI: 10.4161/Cc.26963 |
0.498 |
|
2013 |
Choi S, Bakkenist CJ. Brd4 shields chromatin from ATM kinase signaling storms. Science Signaling. 6: pe30. PMID 24045152 DOI: 10.1126/Scisignal.2004622 |
0.701 |
|
2013 |
Gamper AM, Rofougaran R, Watkins SC, Greenberger JS, Beumer JH, Bakkenist CJ. ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage. Nucleic Acids Research. 41: 10334-44. PMID 24038466 DOI: 10.1093/Nar/Gkt833 |
0.558 |
|
2013 |
Bakkenist CJ, Czambel RK, Clump DA, Greenberger JS, Beumer JH, Schmitz JC. Radiation therapy induces the DNA damage response in peripheral blood. Oncotarget. 4: 1143-8. PMID 23900392 DOI: 10.18632/Oncotarget.1084 |
0.509 |
|
2013 |
Uttam S, Bista RK, Staton K, Alexandrov S, Choi S, Bakkenist CJ, Hartman DJ, Brand RE, Liu Y. Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation. Biomedical Optics Express. 4: 596-613. PMID 23577294 DOI: 10.1364/Boe.4.000596 |
0.656 |
|
2013 |
Gandhi M, Evdokimova VN, Cuenco KT, Bakkenist CJ, Nikiforov YE. Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G₀-phase human cells. Cell Cycle (Georgetown, Tex.). 12: 547-52. PMID 23370393 DOI: 10.4161/Cc.23754 |
0.406 |
|
2012 |
Qian W, Choi S, Gibson GA, Watkins SC, Bakkenist CJ, Van Houten B. Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress. Journal of Cell Science. 125: 5745-57. PMID 23015593 DOI: 10.1242/Jcs.109769 |
0.699 |
|
2012 |
Choi S, Srivas R, Fu KY, Hood BL, Dost B, Gibson GA, Watkins SC, Van Houten B, Bandeira N, Conrads TP, Ideker T, Bakkenist CJ. Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes. Journal of Proteome Research. 11: 4983-91. PMID 22909323 DOI: 10.1021/Pr3005524 |
0.744 |
|
2012 |
Yamamoto K, Wang Y, Jiang W, Liu X, Dubois RL, Lin CS, Ludwig T, Bakkenist CJ, Zha S. Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice. The Journal of Cell Biology. 198: 305-13. PMID 22869596 DOI: 10.1083/Jcb.201204098 |
0.546 |
|
2012 |
Gandhi M, Evdokimova VN, T Cuenco K, Nikiforova MN, Kelly LM, Stringer JR, Bakkenist CJ, Nikiforov YE. Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G0/G1-phase human cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 9454-9. PMID 22645362 DOI: 10.1073/Pnas.1205759109 |
0.528 |
|
2012 |
Gamper AM, Choi S, Matsumoto Y, Banerjee D, Tomkinson AE, Bakkenist CJ. ATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis. The Journal of Biological Chemistry. 287: 12445-54. PMID 22362778 DOI: 10.1074/Jbc.M112.352310 |
0.747 |
|
2012 |
Evdokimova VN, Gandhi M, Bakkenist CJ, Nikiforov YE. Abstract 2125: A new method for assessing fidelity of DSB repair shows involvement of different DNA repair mechanisms at specific sites in human genome Cancer Research. 72: 2125-2125. DOI: 10.1158/1538-7445.Am2012-2125 |
0.374 |
|
2011 |
Bernard ME, Kim H, Berhane H, Epperly MW, Franicola D, Zhang X, Houghton F, Shields D, Wang H, Bakkenist CJ, Frantz MC, Forbeck EM, Goff JP, Wipf P, Greenberger JS. GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines. Radiation Research. 176: 603-12. PMID 21939290 DOI: 10.1667/Rr2624.1 |
0.42 |
|
2011 |
Choi S, Toledo LI, Fernandez-Capetillo O, Bakkenist CJ. CGK733 does not inhibit ATM or ATR kinase activity in H460 human lung cancer cells. Dna Repair. 10: 1000-1; author reply. PMID 21865098 DOI: 10.1016/J.Dnarep.2011.07.013 |
0.742 |
|
2011 |
Bista RK, Uttam S, Wang P, Staton K, Choi S, Bakkenist CJ, Hartman DJ, Brand RE, Liu Y. Quantification of nanoscale nuclear refractive index changes during the cell cycle. Journal of Biomedical Optics. 16: 070503. PMID 21806245 DOI: 10.1117/1.3597723 |
0.709 |
|
2011 |
White JS, Yue N, Hu J, Bakkenist CJ. The ATM kinase signaling induced by the low-energy β-particles emitted by (33)P is essential for the suppression of chromosome aberrations and is greater than that induced by the energetic β-particles emitted by (32)P. Mutation Research. 708: 28-36. PMID 21315088 DOI: 10.1016/J.Mrfmmm.2011.01.005 |
0.417 |
|
2011 |
Bernard ME, Epperly MW, Franicola D, Zhang X, Shields D, Houghton F, Bakkenist CJ, Guinan EC, Kannan N, Greenberger JS. Abstract 2503: Distinct radiosensitivities of human FancG-/- and FancD2-/- cell lines Cancer Research. 71: 2503-2503. DOI: 10.1158/1538-7445.Am2011-2503 |
0.361 |
|
2011 |
Bernard ME, Kim H, Epperly MW, Franicola D, Zhang X, Shields D, Houghton FD, Bakkenist CJ, Greenberger JS. GS-Nitroxide (JP4 - 039) Mediated Radioprotection of Human Fanconi Anemia Cell Lines International Journal of Radiation Oncology Biology Physics. 81. DOI: 10.1016/J.Ijrobp.2011.06.1288 |
0.313 |
|
2010 |
Choi S, Gamper AM, White JS, Bakkenist CJ. Inhibition of ATM kinase activity does not phenocopy ATM protein disruption: implications for the clinical utility of ATM kinase inhibitors. Cell Cycle (Georgetown, Tex.). 9: 4052-7. PMID 20953138 DOI: 10.4161/Cc.9.20.13471 |
0.74 |
|
2010 |
Rajagopalan MS, Stone B, Rwigema JC, Salimi U, Epperly MW, Goff J, Franicola D, Dixon T, Cao S, Zhang X, Buchholz BM, Bauer AJ, Choi S, Bakkenist C, Wang H, et al. Intraesophageal manganese superoxide dismutase-plasmid liposomes ameliorates novel total-body and thoracic radiation sensitivity of NOS1-/- mice. Radiation Research. 174: 297-312. PMID 20726721 DOI: 10.1667/Rr2019.1 |
0.635 |
|
2010 |
White JS, Choi S, Bakkenist CJ. Transient ATM kinase inhibition disrupts DNA damage-induced sister chromatid exchange. Science Signaling. 3: ra44. PMID 20516478 DOI: 10.1126/Scisignal.2000758 |
0.774 |
|
2010 |
Xu X, Vatsyayan J, Gao C, Bakkenist CJ, Hu J. Sumoylation of eIF4E activates mRNA translation. Embo Reports. 11: 299-304. PMID 20224576 DOI: 10.1038/Embor.2010.18 |
0.323 |
|
2009 |
Goff JP, Shields DS, Seki M, Choi S, Epperly MW, Dixon T, Wang H, Bakkenist CJ, Dertinger SD, Torous DK, Wittschieben J, Wood RD, Greenberger JS. Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation. Radiation Research. 172: 165-74. PMID 19630521 DOI: 10.1667/Rr1598.1 |
0.737 |
|
2009 |
Momcilović O, Choi S, Varum S, Bakkenist C, Schatten G, Navara C. Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 1822-35. PMID 19544417 DOI: 10.1002/Stem.123 |
0.755 |
|
2008 |
White JS, Choi S, Bakkenist CJ. Irreversible chromosome damage accumulates rapidly in the absence of ATM kinase activity. Cell Cycle (Georgetown, Tex.). 7: 1277-84. PMID 18418045 DOI: 10.4161/Cc.7.9.5961 |
0.747 |
|
2007 |
Parikh RA, White JS, Huang X, Schoppy DW, Baysal BE, Baskaran R, Bakkenist CJ, Saunders WS, Hsu LC, Romkes M, Gollin SM. Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma. Genes, Chromosomes & Cancer. 46: 761-75. PMID 17492757 DOI: 10.1002/Gcc.20462 |
0.359 |
|
2006 |
Gollin SM, Parikh RA, White JS, Huang X, Baskaran R, Saunders WS, Bakkenist CJ, Reshmi SC. S041 Identification of the Mechanism of 11q13 Amplification Leads to Detection of DNA Repair Defects in HNSCC Cell Lines Archives of Otolaryngology–Head & Neck Surgery. 132: 848. DOI: 10.1001/Archotol.132.8.848-A |
0.377 |
|
2005 |
Bartkova J, Bakkenist CJ, Rajpert-De Meyts E, Skakkebaek NE, Sehested M, Lukas J, Kastan MB, Bartek J. ATM activation in normal human tissues and testicular cancer. Cell Cycle (Georgetown, Tex.). 4: 838-45. PMID 15846060 DOI: 10.4161/Cc.4.6.1742 |
0.51 |
|
2005 |
Kastan M, Kitagawa R, Bakkenist C. DNA damage response pathways in cancer causation and treatment Breast Cancer Research. 7: 1-2. DOI: 10.1186/Bcr1049 |
0.601 |
|
2004 |
Karlseder J, Hoke K, Mirzoeva OK, Bakkenist C, Kastan MB, Petrini JH, de Lange T. The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response. Plos Biology. 2: E240. PMID 15314656 DOI: 10.1371/Journal.Pbio.0020240 |
0.548 |
|
2004 |
Bakkenist CJ, Kastan MB. Phosphatases join kinases in DNA-damage response pathways. Trends in Cell Biology. 14: 339-41. PMID 15246426 DOI: 10.1016/J.Tcb.2004.05.001 |
0.501 |
|
2004 |
Bakkenist CJ, Kastan MB. Initiating cellular stress responses. Cell. 118: 9-17. PMID 15242640 DOI: 10.1016/J.Cell.2004.06.023 |
0.47 |
|
2004 |
Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB. Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes & Development. 18: 1423-38. PMID 15175241 DOI: 10.1101/Gad.1200304 |
0.576 |
|
2004 |
Bakkenist CJ, Drissi R, Wu J, Kastan MB, Dome JS. Disappearance of the telomere dysfunction-induced stress response in fully senescent cells. Cancer Research. 64: 3748-52. PMID 15172978 DOI: 10.1158/0008-5472.Can-04-0453 |
0.424 |
|
2004 |
Horejsí Z, Falck J, Bakkenist CJ, Kastan MB, Lukas J, Bartek J. Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation. Oncogene. 23: 3122-7. PMID 15048089 DOI: 10.1038/Sj.Onc.1207447 |
0.533 |
|
2003 |
Cortés ML, Bakkenist CJ, Di Maria MV, Kastan MB, Breakefield XO. HSV-1 amplicon vector-mediated expression of ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype. Gene Therapy. 10: 1321-7. PMID 12883528 DOI: 10.1038/Sj.Gt.3301996 |
0.403 |
|
2003 |
Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature. 421: 499-506. PMID 12556884 DOI: 10.1038/Nature01368 |
0.564 |
|
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