Tim Schedl - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Genetics & Genomics) Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology, Human Development, Genetics, Cell Biology

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Tolkin T, Mohammad A, Starich TA, Nguyen KCQ, Hall DH, Schedl T, Hubbard EJA, Greenstein D. Innexin function dictates the spatial relationship between distal somatic cells in the gonad without impacting the germline stem cell pool. Elife. 11. PMID 36098634 DOI: 10.7554/eLife.74955  0.325
2022 Brenner JL, Jyo EM, Mohammad A, Fox P, Jones V, Mardis E, Schedl T, Maine EM. TRIM-NHL protein, NHL-2, modulates cell fate choices in the C. elegans germ line. Developmental Biology. 491: 43-55. PMID 36063869 DOI: 10.1016/j.ydbio.2022.08.010  0.389
2020 Tsatskis Y, Rosenfeld R, Pearson JD, Boswell C, Qu Y, Kim K, Fabian L, Mohammad A, Wang X, Robson MI, Krchma K, Wu J, Gonçalves J, Hodzic D, Wu S, ... ... Schedl T, et al. The NEMP family supports metazoan fertility and nuclear envelope stiffness. Science Advances. 6: eabb4591. PMID 32923640 DOI: 10.1126/Sciadv.Abb4591  0.336
2020 Chen J, Mohammad A, Pazdernik N, Huang H, Bowman B, Tycksen E, Schedl T. GLP-1 Notch-LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1. Plos Genetics. 16: e1008650. PMID 32196486 DOI: 10.1371/Journal.Pgen.1008650  0.497
2019 Albert Hubbard EJ, Schedl T. Biology of the Germline Stem Cell System. Genetics. 213: 1145-1188. PMID 31796552 DOI: 10.1534/Genetics.119.300238  0.424
2019 Kocsisova Z, Kornfeld K, Schedl T. Rapid, population-wide declines in stem cell number and activity during reproductive aging in . Development (Cambridge, England). PMID 30936182 DOI: 10.1242/Dev.173195  0.388
2018 Kocsisova Z, Mohammad A, Kornfeld K, Schedl T. Cell Cycle Analysis in the C. elegans Germline with the Thymidine Analog EdU. Journal of Visualized Experiments : Jove. PMID 30394383 DOI: 10.3791/58339  0.436
2018 Mohammad A, Vanden Broek K, Wang C, Daryabeigi A, Jantsch V, Hansen D, Schedl T. Initiation of Meiotic Development Is Controlled by Three Posttranscriptional Pathways in . Genetics. PMID 29941619 DOI: 10.1534/Genetics.118.300985  0.526
2018 Kocsisova Z, Kornfeld K, Schedl T. Cell cycle accumulation of the proliferating cell nuclear antigen PCN-1 transitions from continuous in the adult germline to intermittent in the early embryo of C. elegans. Bmc Developmental Biology. 18: 12. PMID 29848313 DOI: 10.1186/S12861-018-0171-7  0.416
2016 Brenner JL, Schedl T. Indirect Immunofluorescence of Proteins in Oogenic Germ Cells of Caenorhabditis elegans. Methods in Molecular Biology (Clifton, N.J.). 1457: 9-17. PMID 27557570 DOI: 10.1007/978-1-4939-3795-0_2  0.422
2016 Brenner JL, Schedl T. Germline Stem Cell Differentiation Entails Regional Control of Cell Fate Regulator GLD-1 in Caenorhabditis elegans. Genetics. 202: 1085-103. PMID 26757772 DOI: 10.1534/Genetics.115.185678  0.514
2015 Rastogi S, Borgo B, Pazdernik N, Fox P, Mardis ER, Kohara Y, Havranek J, Schedl T. Caenorhabditis elegans glp-4 Encodes a Valyl Aminoacyl tRNA Synthetase. G3 (Bethesda, Md.). PMID 26464357 DOI: 10.1534/G3.115.021899  0.461
2015 Fox PM, Schedl T. Analysis of Germline Stem Cell Differentiation Following Loss of GLP-1 Notch Activity in Caenorhabditis elegans. Genetics. 201: 167-84. PMID 26158953 DOI: 10.1534/Genetics.115.178061  0.436
2015 Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, Moley K, Schedl T, Wang Q. Differential function of pyruvate dehydrogenase kinases during mouse oocyte maturation. Journal of Cell Science. PMID 25991547 DOI: 10.1242/Jcs.167049  0.343
2014 Ma R, Hou X, Zhang L, Sun SC, Schedl T, Moley K, Wang Q. Rab5a is required for spindle length control and kinetochore-microtubule attachment during meiosis in oocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4026-35. PMID 24876181 DOI: 10.1096/Fj.14-250886  0.348
2014 Zhang L, Hou X, Ma R, Moley K, Schedl T, Wang Q. Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1435-45. PMID 24334550 DOI: 10.1096/Fj.13-244111  0.326
2013 Hansen D, Schedl T. Stem cell proliferation versus meiotic fate decision in Caenorhabditis elegans. Advances in Experimental Medicine and Biology. 757: 71-99. PMID 22872475 DOI: 10.1007/978-1-4614-4015-4_4  0.52
2013 Pazdernik N, Schedl T. Introduction to germ cell development in Caenorhabditis elegans. Advances in Experimental Medicine and Biology. 757: 1-16. PMID 22872472 DOI: 10.1007/978-1-4614-4015-4_1  0.477
2012 Wang C, Wilson-Berry L, Schedl T, Hansen D. TEG-1 CD2BP2 regulates stem cell proliferation and sex determination in the C. elegans germ line and physically interacts with the UAF-1 U2AF65 splicing factor. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 505-21. PMID 22275078 DOI: 10.1002/Dvdy.23735  0.51
2011 Arur S, Ohmachi M, Berkseth M, Nayak S, Hansen D, Zarkower D, Schedl T. MPK-1 ERK controls membrane organization in C. elegans oogenesis via a sex-determination module. Developmental Cell. 20: 677-88. PMID 21571224 DOI: 10.1016/J.Devcel.2011.04.009  0.432
2011 Fox PM, Vought VE, Hanazawa M, Lee MH, Maine EM, Schedl T. Cyclin E and CDK-2 regulate proliferative cell fate and cell cycle progression in the C. elegans germline. Development (Cambridge, England). 138: 2223-34. PMID 21558371 DOI: 10.1242/Dev.059535  0.511
2011 Green RA, Kao HL, Audhya A, Arur S, Mayers JR, Fridolfsson HN, Schulman M, Schloissnig S, Niessen S, Laband K, Wang S, Starr DA, Hyman AA, Schedl T, Desai A, et al. A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell. 145: 470-82. PMID 21529718 DOI: 10.1016/J.Cell.2011.03.037  0.356
2011 Sengupta P, Schedl T. Cellular reprogramming: chromatin puts on the brake. Current Biology : Cb. 21: R157-9. PMID 21334296 DOI: 10.1016/J.Cub.2010.12.044  0.439
2010 Wang Q, Frolova AI, Purcell S, Adastra K, Schoeller E, Chi MM, Schedl T, Moley KH. Mitochondrial dysfunction and apoptosis in cumulus cells of type I diabetic mice. Plos One. 5: e15901. PMID 21209947 DOI: 10.1371/Journal.Pone.0015901  0.303
2010 Lee MH, Schedl T. C. elegans star proteins, GLD-1 and ASD-2, regulate specific RNA targets to control development. Advances in Experimental Medicine and Biology. 693: 106-22. PMID 21189689 DOI: 10.1007/978-1-4419-7005-3_8  0.395
2010 Kerins JA, Hanazawa M, Dorsett M, Schedl T. PRP-17 and the pre-mRNA splicing pathway are preferentially required for the proliferation versus meiotic development decision and germline sex determination in Caenorhabditis elegans. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 1555-72. PMID 20419786 DOI: 10.1002/Dvdy.22274  0.529
2010 Howell K, Arur S, Schedl T, Sundaram MV. EOR-2 is an obligate binding partner of the BTB-zinc finger protein EOR-1 in Caenorhabditis elegans. Genetics. 184: 899-913. PMID 20065070 DOI: 10.1534/Genetics.109.111591  0.374
2009 Dorsett M, Schedl T. A role for dynein in the inhibition of germ cell proliferative fate. Molecular and Cellular Biology. 29: 6128-39. PMID 19752194 DOI: 10.1128/Mcb.00815-09  0.767
2009 Dorsett M, Westlund B, Schedl T. METT-10, a putative methyltransferase, inhibits germ cell proliferative fate in Caenorhabditis elegans. Genetics. 183: 233-47. PMID 19596901 DOI: 10.1534/Genetics.109.105270  0.773
2009 Arur S, Ohmachi M, Nayak S, Hayes M, Miranda A, Hay A, Golden A, Schedl T. Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development. Proceedings of the National Academy of Sciences of the United States of America. 106: 4776-81. PMID 19264959 DOI: 10.1073/Pnas.0812285106  0.443
2007 Lee MH, Ohmachi M, Arur S, Nayak S, Francis R, Church D, Lambie E, Schedl T. Multiple functions and dynamic activation of MPK-1 extracellular signal-regulated kinase signaling in Caenorhabditis elegans germline development. Genetics. 177: 2039-62. PMID 18073423 DOI: 10.1534/Genetics.107.081356  0.467
2007 Ellis R, Schedl T. Sex determination in the germ line. Wormbook : the Online Review of C. Elegans Biology. 1-13. PMID 18050498 DOI: 10.1895/Wormbook.1.82.2  0.492
2007 Jantsch V, Tang L, Pasierbek P, Penkner A, Nayak S, Baudrimont A, Schedl T, Gartner A, Loidl J. Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing. Molecular Biology of the Cell. 18: 4911-20. PMID 17914060 DOI: 10.1091/Mbc.E07-03-0243  0.361
2006 Lee MH, Schedl T. RNA-binding proteins. Wormbook : the Online Review of C. Elegans Biology. 1-13. PMID 18050487 DOI: 10.1895/Wormbook.1.79.1  0.38
2006 Hansen D, Schedl T. The regulatory network controlling the proliferation-meiotic entry decision in the Caenorhabditis elegans germ line. Current Topics in Developmental Biology. 76: 185-215. PMID 17118267 DOI: 10.1016/S0070-2153(06)76006-9  0.543
2005 Schumacher B, Hanazawa M, Lee MH, Nayak S, Volkmann K, Hofmann ER, Hofmann R, Hengartner M, Schedl T, Gartner A. Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis. Cell. 120: 357-68. PMID 15707894 DOI: 10.1016/J.Cell.2004.12.009  0.427
2005 Nayak S, Goree J, Schedl T. fog-2 and the evolution of self-fertile hermaphroditism in Caenorhabditis. Plos Biology. 3: e6. PMID 15630478 DOI: 10.1371/Journal.Pbio.0030006  0.441
2004 Tian X, Hansen D, Schedl T, Skeath JB. Epsin potentiates Notch pathway activity in Drosophila and C. elegans. Development (Cambridge, England). 131: 5807-15. PMID 15539484 DOI: 10.1242/Dev.01459  0.473
2004 Lee MH, Schedl T. Translation repression by GLD-1 protects its mRNA targets from nonsense-mediated mRNA decay in C. elegans. Genes & Development. 18: 1047-59. PMID 15105376 DOI: 10.1101/Gad.1188404  0.351
2004 Hansen D, Hubbard EJ, Schedl T. Multi-pathway control of the proliferation versus meiotic development decision in the Caenorhabditis elegans germline. Developmental Biology. 268: 342-57. PMID 15063172 DOI: 10.1016/J.Ydbio.2003.12.023  0.458
2004 Wiederkehr C, Basavaraj R, Sarrauste de Menthière C, Hermida L, Koch R, Schlecht U, Amon A, Brachat S, Breitenbach M, Briza P, Caburet S, Cherry M, Davis R, Deutschbauer A, Dickinson HG, ... ... Schedl T, et al. GermOnline, a cross-species community knowledgebase on germ cell differentiation. Nucleic Acids Research. 32: D560-7. PMID 14681481 DOI: 10.1093/Nar/Gkh055  0.332
2004 Hansen D, Wilson-Berry L, Dang T, Schedl T. Control of the proliferation versus meiotic development decision in the C. elegans germline through regulation of GLD-1 protein accumulation. Development (Cambridge, England). 131: 93-104. PMID 14660440 DOI: 10.1242/Dev.00916  0.543
2002 Ohmachi M, Rocheleau CE, Church D, Lambie E, Schedl T, Sundaram MV. C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation. Current Biology : Cb. 12: 427-33. PMID 11882296 DOI: 10.1016/S0960-9822(02)00690-5  0.39
2002 Nayak S, Santiago FE, Jin H, Lin D, Schedl T, Kipreos ET. The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell proliferation, morphogenesis, and meiosis. Current Biology : Cb. 12: 277-87. PMID 11864567 DOI: 10.1016/S0960-9822(02)00682-6  0.385
2001 Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 107: 27-41. PMID 11595183 DOI: 10.1016/S0092-8674(01)00520-7  0.492
2001 Lee MH, Schedl T. Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development. Genes & Development. 15: 2408-20. PMID 11562350 DOI: 10.1101/Gad.915901  0.43
2001 Miller MA, Nguyen VQ, Lee MH, Kosinski M, Schedl T, Caprioli RM, Greenstein D. A sperm cytoskeletal protein that signals oocyte meiotic maturation and ovulation. Science (New York, N.Y.). 291: 2144-7. PMID 11251118 DOI: 10.1126/Science.1057586  0.403
2001 Seydoux G, Schedl T. The germline in C. elegans: origins, proliferation, and silencing. International Review of Cytology. 203: 139-85. PMID 11131515 DOI: 10.1016/S0074-7696(01)03006-6  0.48
2000 Kuwabara PE, Lee MH, Schedl T, Jefferis GS. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Genes & Development. 14: 1933-44. PMID 10921907 DOI: 10.1101/Gad.14.15.1933  0.487
1999 McCarter J, Bartlett B, Dang T, Schedl T. On the control of oocyte meiotic maturation and ovulation in Caenorhabditis elegans. Developmental Biology. 205: 111-28. PMID 9882501 DOI: 10.1006/Dbio.1998.9109  0.405
1997 McCarter J, Bartlett B, Dang T, Schedl T. Soma-germ cell interactions in Caenorhabditis elegans: multiple events of hermaphrodite germline development require the somatic sheath and spermathecal lineages. Developmental Biology. 181: 121-43. PMID 9013925 DOI: 10.1006/Dbio.1996.8429  0.476
1997 Jones AR, Francis R, Schedl T. GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Developmental Biology. 180: 165-83. PMID 8948583 DOI: 10.1006/Dbio.1996.0293  0.511
1996 Iwasaki K, McCarter J, Francis R, Schedl T. emo-1, a Caenorhabditis elegans Sec61p gamma homologue, is required for oocyte development and ovulation. The Journal of Cell Biology. 134: 699-714. PMID 8707849 DOI: 10.1083/Jcb.134.3.699  0.401
1996 Kloek AP, McCarter JP, Setterquist RA, Schedl T, Goldberg DE. Caenorhabditis globin genes: rapid intronic divergence contrasts with conservation of silent exonic sites. Journal of Molecular Evolution. 43: 101-8. PMID 8660434 DOI: 10.1007/Bf02337354  0.34
1995 Jones AR, Schedl T. Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68. Genes & Development. 9: 1491-504. PMID 7601353 DOI: 10.1101/Gad.9.12.1491  0.342
1994 Clifford R, Francis R, Schedl T. Somatic control of germ cell development in Caenorhabditis elegans Seminars in Developmental Biology. 5: 21-30. DOI: 10.1006/Sedb.1994.1004  0.492
1993 Graham PL, Schedl T, Kimble J. More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans. Developmental Genetics. 14: 471-484. PMID 8111975 DOI: 10.1002/Dvg.1020140608  0.417
1992 Schedl T. The role of cell-cell interactions in postembryonic development of the Caenorhabditis elegans germ line. Current Opinion in Genetics & Development. 1: 185-90. PMID 1822268 DOI: 10.1016/S0959-437X(05)80068-1  0.382
1990 Seydoux G, Schedl T, Greenwald I. Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans. Cell. 61: 939-51. PMID 2350786 DOI: 10.1016/0092-8674(90)90060-R  0.411
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