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Michael J. Bouchard - Publications

Affiliations: 
Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Cell Biology, Virology Biology
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Duchemin NJ, Loonawat R, Yeakle K, Rosenkranz A, Bouchard MJ. Hypoxia-inducible factor affects hepatitis B virus transcripts and genome levels as well as the expression and subcellular location of the hepatitis B virus core protein. Virology. 586: 76-90. PMID 37490813 DOI: 10.1016/j.virol.2023.06.013  0.575
2022 Sarfaraz N, Somarowthu S, Bouchard MJ. The interplay of long noncoding RNAs and hepatitis B virus. Journal of Medical Virology. PMID 35946066 DOI: 10.1002/jmv.28058  0.495
2018 Slagle BL, Bouchard MJ. Role of HBx in hepatitis B virus persistence and its therapeutic implications. Current Opinion in Virology. 30: 32-38. PMID 29454995 DOI: 10.1016/J.Coviro.2018.01.007  0.57
2018 Lamontagne RJ, Casciano JC, Bouchard MJ. A broad investigation of the HBV-mediated changes to primary hepatocyte physiology reveals HBV significantly alters metabolic pathways. Metabolism: Clinical and Experimental. PMID 29410347 DOI: 10.1016/J.Metabol.2018.01.007  0.554
2018 Casciano JC, Bouchard MJ. Hepatitis B virus X protein modulates cytosolic Ca2+ signaling in primary human hepatocytes. Virus Research. 246: 23-27. PMID 29307794 DOI: 10.1016/J.Virusres.2018.01.001  0.552
2017 Casciano JC, Duchemin NJ, Lamontagne RJ, Steel LF, Bouchard MJ. Hepatitis B virus modulates store-operated calcium entry to enhance viral replication in primary hepatocytes. Plos One. 12: e0168328. PMID 28151934 DOI: 10.1371/Journal.Pone.0168328  0.469
2017 Casciano JC, Bouchard MJ. Measuring Changes in Cytosolic Calcium Levels in HBV- and HBx-Expressing Cultured Primary Hepatocytes. Methods in Molecular Biology (Clifton, N.J.). 1540: 143-155. PMID 27975314 DOI: 10.1007/978-1-4939-6700-1_12  0.57
2017 Kang Y, Rawat S, Duchemin N, Bouchard M, Noh M. Human Liver Sinusoid on a Chip for Hepatitis B Virus Replication Study Micromachines. 8: 27. DOI: 10.3390/Mi8010027  0.813
2016 Lamontagne RJ, Bagga S, Bouchard MJ. Hepatitis B virus molecular biology and pathogenesis. Hepatoma Research. 2: 163-186. PMID 28042609 DOI: 10.20517/2394-5079.2016.05  0.531
2016 Bagga S, Rawat S, Ajenjo M, Bouchard MJ. Hepatitis B virus (HBV) X protein-mediated regulation of hepatocyte metabolic pathways affects viral replication. Virology. 498: 9-22. PMID 27529294 DOI: 10.1016/J.Virol.2016.08.006  0.838
2016 Mehta A, Comunale MA, Rawat S, Casciano JC, Lamontagne J, Herrera H, Ramanathan A, Betesh L, Wang M, Norton P, Steel LF, Bouchard MJ. Intrinsic hepatocyte dedifferentiation is accompanied by upregulation of mesenchymal markers, protein sialylation and core alpha 1,6 linked fucosylation. Scientific Reports. 6: 27965. PMID 27328854 DOI: 10.1038/Srep27965  0.778
2016 Lamontagne J, Mell JC, Bouchard MJ. Transcriptome-Wide Analysis of Hepatitis B Virus-Mediated Changes to Normal Hepatocyte Gene Expression. Plos Pathogens. 12: e1005438. PMID 26891448 DOI: 10.1371/Journal.Ppat.1005438  0.564
2016 Slagle BL, Bouchard MJ. Hepatitis B Virus X and Regulation of Viral Gene Expression. Cold Spring Harbor Perspectives in Medicine. 6. PMID 26747833 DOI: 10.1101/Cshperspect.A021402  0.552
2015 Shah AD, Bouchard MJ, Shieh AC. Interstitial Fluid Flow Increases Hepatocellular Carcinoma Cell Invasion through CXCR4/CXCL12 and MEK/ERK Signaling. Plos One. 10: e0142337. PMID 26560447 DOI: 10.1371/Journal.Pone.0142337  0.397
2015 Lamontagne J, Steel LF, Bouchard MJ. Hepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseases. World Journal of Gastroenterology. 21: 7375-99. PMID 26139985 DOI: 10.3748/Wjg.V21.I24.7375  0.472
2015 Kang YB, Sodunke TR, Lamontagne J, Cirillo J, Rajiv C, Bouchard MJ, Noh M. Liver sinusoid on a chip: Long-term layered co-culture of primary rat hepatocytes and endothelial cells in microfluidic platforms. Biotechnology and Bioengineering. PMID 25994312 DOI: 10.1002/Bit.25659  0.491
2015 Rawat S, Bouchard MJ. The hepatitis B virus (HBV) HBx protein activates AKT to simultaneously regulate HBV replication and hepatocyte survival Journal of Virology. 89: 999-1012. PMID 25355887 DOI: 10.1128/Jvi.02440-14  0.843
2015 Slagle BL, Andrisani OM, Bouchard MJ, Lee CG, Ou JH, Siddiqui A. Technical standards for hepatitis B virus X protein (HBx) research. Hepatology (Baltimore, Md.). 61: 1416-24. PMID 25099228 DOI: 10.1002/Hep.27360  0.619
2015 Mehta AS, Comunale MA, Rawat S, Garner J, Betesh L, Wang M, Steel L, Bouchard M. Abstract 4982: Increased core fucosylation, a glycan alteration associated with cancer, is the result of hepatocyte dedifferentiation Cancer Research. 75: 4982-4982. DOI: 10.1158/1538-7445.Am2015-4982  0.78
2015 Shah AD, Bouchard M, Shieh AC. Abstract 4155: Interstitial fluid flow-induced hepatocellular carcinoma cell invasion requires MEK/ERK signaling Cancer Research. 75: 4155-4155. DOI: 10.1158/1538-7445.Am2015-4155  0.434
2014 Bagga S, Bouchard MJ. Cell cycle regulation during viral infection. Methods in Molecular Biology (Clifton, N.J.). 1170: 165-227. PMID 24906315 DOI: 10.1007/978-1-4939-0888-2_10  0.439
2014 Rice LM, Donigan M, Yang M, Liu W, Pandya D, Joseph BK, Sodi V, Gearhart TL, Yip J, Bouchard M, Nickels JT. Protein phosphatase 2A (PP2A) regulates low density lipoprotein uptake through regulating sterol response element-binding protein-2 (SREBP-2) DNA binding. The Journal of Biological Chemistry. 289: 17268-79. PMID 24770487 DOI: 10.1074/Jbc.M114.570390  0.733
2013 Kang YB, Rawat S, Cirillo J, Bouchard M, Noh HM. Layered long-term co-culture of hepatocytes and endothelial cells on a transwell membrane: toward engineering the liver sinusoid. Biofabrication. 5: 045008. PMID 24280542 DOI: 10.1088/1758-5082/5/4/045008  0.761
2012 Rawat S, Clippinger AJ, Bouchard MJ. Modulation of apoptotic signaling by the hepatitis B virus X protein. Viruses. 4: 2945-72. PMID 23202511 DOI: 10.3390/V4112945  0.81
2012 Yang B, Bouchard MJ. The hepatitis B virus X protein elevates cytosolic calcium signals by modulating mitochondrial calcium uptake. Journal of Virology. 86: 313-27. PMID 22031934 DOI: 10.1128/Jvi.06442-11  0.51
2011 Bouchard MJ, Navas-Martin S. Hepatitis B and C virus hepatocarcinogenesis: lessons learned and future challenges. Cancer Letters. 305: 123-43. PMID 21168955 DOI: 10.1016/J.Canlet.2010.11.014  0.517
2011 Lizzano RA, Yang B, Clippinger AJ, Bouchard MJ. The C-terminal region of the hepatitis B virus X protein is essential for its stability and function. Virus Research. 155: 231-9. PMID 20969903 DOI: 10.1016/J.Virusres.2010.10.013  0.794
2011 Gearhart TL, Bouchard MJ. The hepatitis B virus HBx protein modulates cell cycle regulatory proteins in cultured primary human hepatocytes. Virus Research. 155: 363-7. PMID 20934470 DOI: 10.1016/J.Virusres.2010.09.023  0.816
2010 Gearhart TL, Bouchard MJ. Replication of the hepatitis B virus requires a calcium-dependent HBx-induced G1 phase arrest of hepatocytes. Virology. 407: 14-25. PMID 20719353 DOI: 10.1016/J.Virol.2010.07.042  0.813
2010 Gearhart TL, Bouchard MJ. The hepatitis B virus X protein modulates hepatocyte proliferation pathways to stimulate viral replication. Journal of Virology. 84: 2675-86. PMID 20053744 DOI: 10.1128/Jvi.02196-09  0.837
2009 Clippinger AJ, Gearhart TL, Bouchard MJ. Hepatitis B virus X protein modulates apoptosis in primary rat hepatocytes by regulating both NF-kappaB and the mitochondrial permeability transition pore. Journal of Virology. 83: 4718-31. PMID 19279112 DOI: 10.1128/Jvi.02590-08  0.787
2008 Clippinger AJ, Bouchard MJ. Hepatitis B virus HBx protein localizes to mitochondria in primary rat hepatocytes and modulates mitochondrial membrane potential. Journal of Virology. 82: 6798-811. PMID 18448529 DOI: 10.1128/Jvi.00154-08  0.75
2008 Sodunke TR, Bouchard MJ, Noh HM. Microfluidic platform for hepatitis B viral replication study. Biomedical Microdevices. 10: 393-402. PMID 18165913 DOI: 10.1007/S10544-007-9148-1  0.576
2007 McClain SL, Clippinger AJ, Lizzano R, Bouchard MJ. Hepatitis B virus replication is associated with an HBx-dependent mitochondrion-regulated increase in cytosolic calcium levels. Journal of Virology. 81: 12061-5. PMID 17699583 DOI: 10.1128/Jvi.00740-07  0.78
2006 Bouchard MJ, Wang L, Schneider RJ. Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication. Journal of Virology. 80: 4406-14. PMID 16611900 DOI: 10.1128/Jvi.80.9.4406-4414.2006  0.538
2004 Bouchard MJ, Schneider RJ. The enigmatic X gene of hepatitis B virus. Journal of Virology. 78: 12725-34. PMID 15542625 DOI: 10.1128/Jvi.78.23.12725-12734.2004  0.593
2003 Bouchard MJ, Puro RJ, Wang L, Schneider RJ. Activation and inhibition of cellular calcium and tyrosine kinase signaling pathways identify targets of the HBx protein involved in hepatitis B virus replication. Journal of Virology. 77: 7713-9. PMID 12829810 DOI: 10.1128/Jvi.77.14.7713-7719.2003  0.59
2001 Bouchard MJ, Wang L, Schneider RJ. Calcium signaling by HBx protein in hepatitis B virus DNA replication. Science. 294: 2376-2378. PMID 11743208 DOI: 10.1126/Science.294.5550.2376  0.542
2001 Bouchard M, Giannakopoulos S, Wang EH, Tanese N, Schneider RJ. Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway. Journal of Virology. 75: 4247-57. PMID 11287574 DOI: 10.1128/Jvi.75.9.4247-4257.2001  0.478
1999 Klein NP, Bouchard MJ, Wang L, Kobarg C, Schneider RJ. Src kinases involved in hepatitis B virus replication The Embo Journal. 18: 5019-5027. PMID 10487754 DOI: 10.1093/Emboj/18.18.5019  0.565
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