Margaret Ng - Publications

Affiliations: 
The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Pathology, Molecular Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tsui SP, Tang TW, Ip H, So JCC, Au CH, Ma ESK, Chan CT, Ng M, Cheng KCK, Wong KF, Siu LL, Yip SF, Lin S, Lau SJ, Luk T, et al. Characterization of Genomic Landscape and Risk Stratification of De Novo Cytogenetically Normal Acute Myeloid Leukaemia Blood. 132: 5267-5267. DOI: 10.1182/Blood-2018-99-118909  0.308
2017 De Santo C, Booth S, Vardon A, Cousins A, Tubb V, Perry T, Noyvert B, Beggs A, Ng M, Halsey C, Kearns P, Cheng P, Mussai F. The arginine metabolome in Acute Lymphoblastic Leukemia can be targeted by the PEG-recombinant Arginase I BCT-100. International Journal of Cancer. PMID 29168171 DOI: 10.1002/Ijc.31170  0.354
2016 Lie R, Cheng CK, Chan NPH, Ip R, Chan N, Cheung J, Ng M. Abstract 1114: Downregulated miR-337-5p is associated with unfavorable features in acute myeloid leukemia and may play a role in modulating the extracellular signal-regulated kinase pathway Cancer Research. 76: 1114-1114. DOI: 10.1158/1538-7445.Am2016-1114  0.327
2015 Mussai F, Egan S, Higginbotham-Jones J, Perry T, Beggs A, Odintsova E, Loke J, Pratt G, U KP, Lo A, Ng M, Kearns P, Cheng P, De Santo C. Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target. Blood. 125: 2386-96. PMID 25710880 DOI: 10.1182/Blood-2014-09-600643  0.341
2015 Mussai FJ, Booth S, Vardon A, Ng M, Cheng P, De Santo C. Cytotoxicity of the Recombinant Human Arginase (BCT-100) Against Acute Lymphoblastic Leukaemia (ALL) Blood. 126: 4916-4916. DOI: 10.1182/Blood.V126.23.4916.4916  0.352
2014 Ma BB, Lui VW, Hui CW, Lau CP, Wong CH, Hui EP, Ng MH, Cheng SH, Tsao SW, Tsang CM, Cheung CS, Ho K, Chan AT. Preclinical evaluation of the mTOR-PI3K inhibitor BEZ235 in nasopharyngeal cancer models. Cancer Letters. 343: 24-32. PMID 24041865 DOI: 10.1016/j.canlet.2013.09.007  0.625
2014 Mussai FJ, Egan S, Higginbotham-Jones J, Lo A, Ng M, Perry TA, Loke J, Beggs AD, Pratt G, Kearns PR, Cheng P, DeSanto C. Cytotoxicity of the Recombinant Human Arginase (BCT-100) Against Acute Myeloid Leukaemia (AML) Blood. 124: 2317-2317. DOI: 10.1182/Blood.V124.21.2317.2317  0.375
2013 Cheng SH, Lau KM, Li CK, Chan NP, Ip RK, Cheng CK, Lee V, Shing MM, Leung AW, Ha SY, Cheuk DK, Lee AC, Li CH, Luk CW, Ling SC, ... ... Ng MH, et al. Minimal residual disease-based risk stratification in Chinese childhood acute lymphoblastic leukemia by flow cytometry and plasma DNA quantitative polymerase chain reaction. Plos One. 8: e69467. PMID 23936021 DOI: 10.1371/Journal.Pone.0069467  0.57
2013 Cheung YK, Cheng SH, Chan EJ, Lo SV, Ng MH, Kwan P. HLA-B alleles associated with severe cutaneous reactions to antiepileptic drugs in Han Chinese. Epilepsia. 54: 1307-14. PMID 23692434 DOI: 10.1111/Epi.12217  0.572
2013 Chen J, Chan AW, To KF, Chen W, Zhang Z, Ren J, Song C, Cheung YS, Lai PB, Cheng SH, Ng MH, Huang A, Ko BC. SIRT2 overexpression in hepatocellular carcinoma mediates epithelial to mesenchymal transition by protein kinase B/glycogen synthase kinase-3β/β-catenin signaling. Hepatology (Baltimore, Md.). 57: 2287-98. PMID 23348706 DOI: 10.1002/Hep.26278  0.609
2013 Cheng CK, Kwan TK, Cheung CY, Ng K, Liang P, Cheng SH, Chan NP, Ip RK, Wong RS, Lee V, Li CK, Yip SF, Ng MH. A polymorphism in the 3'-untranslated region of the NPM1 gene causes illegitimate regulation by microRNA-337-5p and correlates with adverse outcome in acute myeloid leukemia. Haematologica. 98: 913-7. PMID 23065518 DOI: 10.3324/Haematol.2012.073015  0.743
2013 Liang P, Cheng SH, Cheng CK, Lau KM, Lin SY, Chow EY, Chan NP, Ip RK, Wong RS, Ng MH. Platelet factor 4 induces cell apoptosis by inhibition of STAT3 via up-regulation of SOCS3 expression in multiple myeloma. Haematologica. 98: 288-95. PMID 22929979 DOI: 10.3324/Haematol.2012.065607  0.634
2013 Lung RW, Wang X, Tong JH, Chau SL, Lau KM, Cheng SH, Woo JK, Woo J, Leung PC, Ng MH, Tang NL, To KF. A single nucleotide polymorphism in microRNA-146a is associated with the risk for nasopharyngeal carcinoma. Molecular Carcinogenesis. 52: E28-38. PMID 22711332 DOI: 10.1002/Mc.21937  0.577
2013 Ma BB, Lui VW, Cheung CS, Lau CP, Ho K, Hui EP, Tsui SK, Ng MH, Cheng SH, Ng PK, Tsao SW, Chan AT. Activity of the MEK inhibitor selumetinib (AZD6244; ARRY-142886) in nasopharyngeal cancer cell lines. Investigational New Drugs. 31: 30-8. PMID 22565394 DOI: 10.1007/s10637-012-9828-4  0.613
2012 Ng MH, Cheng SH, Lai PB, Ling KK, Lau KM, Cheng CK, Wong N, Zee BC, Lin CK. Association of polymorphism of human leukocyte antigen alleles with development of hepatocellular carcinoma in Hong Kong Chinese. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 18: 37-40. PMID 23249853  0.581
2012 Cheng Y, Liang P, Geng H, Wang Z, Li L, Cheng SH, Ying J, Su X, Ng KM, Ng MH, Mok TS, Chan AT, Tao Q. A novel 19q13 nucleolar zinc finger protein suppresses tumor cell growth through inhibiting ribosome biogenesis and inducing apoptosis but is frequently silenced in multiple carcinomas. Molecular Cancer Research : McR. 10: 925-36. PMID 22679109 DOI: 10.1158/1541-7786.Mcr-11-0594  0.619
2012 Chiu ML, Hu M, Ng MH, Yeung CK, Chan JC, Chang MM, Cheng SH, Li L, Tomlinson B. Association between HLA-B*58:01 allele and severe cutaneous adverse reactions with allopurinol in Han Chinese in Hong Kong. The British Journal of Dermatology. 167: 44-9. PMID 22348415 DOI: 10.1111/J.1365-2133.2012.10894.X  0.572
2012 Zhou Q, Lui VW, Lau CP, Cheng SH, Ng MH, Cai Y, Chan SL, Yeo W. Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma. Biochemical Pharmacology. 83: 1146-58. PMID 22285225 DOI: 10.1016/J.Bcp.2012.01.013  0.627
2012 Ma BB, Lui VW, Hui C, Lau C, Ng M, Tsao SW, Hui EP, Wong CH, Yan L, Chan AT. Abstract 4602: Preclinical evaluation of the AKT inhibitor MK2206 in nasopharyngeal carcinoma cell lines Cancer Research. 72: 4602-4602. DOI: 10.1158/1538-7445.Am2012-4602  0.386
2011 Wing YK, Chen L, Lam SP, Li AM, Tang NL, Ng MH, Cheng SH, Ho CK, Mok V, Leung HW, Lau A, Chan MH, Chan HS, Chan PS. Familial aggregation of narcolepsy. Sleep Medicine. 12: 947-51. PMID 22036600 DOI: 10.1016/J.Sleep.2011.05.007  0.542
2011 Cheng CK, Li L, Cheng SH, Ng K, Chan NP, Ip RK, Wong RS, Shing MM, Li CK, Ng MH. Secreted-frizzled related protein 1 is a transcriptional repression target of the t(8;21) fusion protein in acute myeloid leukemia. Blood. 118: 6638-48. PMID 22031861 DOI: 10.1182/Blood-2011-05-354712  0.612
2011 Chen J, Zhang B, Wong N, Lo AW, To KF, Chan AW, Ng MH, Ho CY, Cheng SH, Lai PB, Yu J, Ng HK, Ling MT, Huang AL, Cai XF, et al. Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth. Cancer Research. 71: 4138-49. PMID 21527554 DOI: 10.1158/0008-5472.Can-10-4274  0.597
2011 Lui VW, Wong EY, Ho K, Ng PK, Lau CP, Tsui SK, Tsang CM, Tsao SW, Cheng SH, Ng MH, Ng YK, Lam EK, Hong B, Lo KW, Mok TS, et al. Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death. Oncogene. 30: 1127-34. PMID 21057531 DOI: 10.1038/Onc.2010.490  0.601
2011 Lui VW, Lau CP, Ho K, Ng MH, Cheng SH, Tsao SW, Tsang CM, Lei KI, Chan AT, Mok TS. Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells. Investigational New Drugs. 29: 1241-52. PMID 20571878 DOI: 10.1007/S10637-010-9470-Y  0.633
2011 Hui EP, Lui VW, Wong CS, Ma BB, Lau CP, Cheung CS, Ho K, Cheng SH, Ng MH, Chan AT. Preclinical evaluation of sunitinib as single agent or in combination with chemotherapy in nasopharyngeal carcinoma. Investigational New Drugs. 29: 1123-31. PMID 20467883 DOI: 10.1007/S10637-010-9451-1  0.582
2011 Hong B, Lui VW, Hui EP, Ng MH, Cheng SH, Sung FL, Tsang CM, Tsao SW, Chan AT. Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation. Investigational New Drugs. 29: 401-10. PMID 20013349 DOI: 10.1007/S10637-009-9356-Z  0.621
2010 Ng MH, Cheng SH, Lau KM, Leung GM, Khoo US, Zee BC, Sung JJ. Immunogenetics in SARS: a case-control study. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 16: 29-33. PMID 20864745  0.527
2010 Cheng Y, Geng H, Cheng SH, Liang P, Bai Y, Li J, Srivastava G, Ng MH, Fukagawa T, Wu X, Chan AT, Tao Q. KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas. Cancer Research. 70: 6516-26. PMID 20682794 DOI: 10.1158/0008-5472.Can-09-4566  0.615
2010 Lui VW, Lau CP, Cheung CS, Ho K, Ng MH, Cheng SH, Hong B, Tsao SW, Tsang CM, Lei KI, Yamasaki Y, Mita A, Chan AT. An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl)cytosine (ECyd), elicits antitumor effect via TP53-induced Glycolysis and Apoptosis Regulator (TIGAR) downregulation. Biochemical Pharmacology. 79: 1772-80. PMID 20219441 DOI: 10.1016/J.Bcp.2010.02.012  0.612
2010 Law BY, Wang M, Ma DL, Al-Mousa F, Michelangeli F, Cheng SH, Ng MH, To KF, Mok AY, Ko RY, Lam SK, Chen F, Che CM, Chiu P, Ko BC. Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis. Molecular Cancer Therapeutics. 9: 718-30. PMID 20197400 DOI: 10.1158/1535-7163.Mct-09-0700  0.598
2010 Hong B, Lui VW, Hui EP, Lu Y, Leung HS, Wong EY, Cheng SH, Ng MH, Mills GB, Chan AT. Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1. Biochemical Pharmacology. 79: 842-52. PMID 19879857 DOI: 10.1016/J.Bcp.2009.10.021  0.613
2010 Mejstríková E, Fronková E, Kalina T, Omelka M, Batinić D, Dubravcić K, Pospísilová K, Vásková M, Luria D, Cheng SH, Ng M, Leung Y, Kappelmayer J, Kiss F, Izraeli S, et al. Detection of residual B precursor lymphoblastic leukemia by uniform gating flow cytometry. Pediatric Blood & Cancer. 54: 62-70. PMID 19760767 DOI: 10.1002/Pbc.22261  0.597
2010 Ma BB, Lui VW, Poon FF, Wong SC, To KF, Wong E, Chen H, Lo KW, Tao Q, Chan AT, Ng MH, Cheng SH. Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response. Investigational New Drugs. 28: 326-33. PMID 19756373 DOI: 10.1007/S10637-009-9316-7  0.626
2010 Wong JH, Lui VW, Umezawa K, Ho Y, Wong EY, Ng MH, Cheng SH, Tsang CM, Tsao SW, Chan AT. A small molecule inhibitor of NF-kappaB, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses growth and invasion of nasopharyngeal carcinoma (NPC) cells. Cancer Letters. 287: 23-32. PMID 19560263 DOI: 10.1016/J.Canlet.2009.05.022  0.608
2010 Ma BB, Lui VW, Hui EP, Lau CP, Ho K, Ng MH, Cheng SH, Tsao SW, Chan AT. The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines. Investigational New Drugs. 28: 413-20. PMID 19471857 DOI: 10.1007/S10637-009-9269-X  0.628
2009 Cheng SH, Kwan P, Ng HK, Ng MH. New testing approach in HLA genotyping helps overcome barriers in effective clinical practice. Clinical Chemistry. 55: 1568-72. PMID 19556444 DOI: 10.1373/Clinchem.2009.127894  0.574
2008 Cheng CK, Li L, Cheng SH, Lau KM, Chan NP, Wong RS, Shing MM, Li CK, Ng MH. Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia. Blood. 112: 3391-402. PMID 18663147 DOI: 10.1182/Blood-2008-02-137083  0.614
2008 Wong RS, Cheng CK, Chan NP, Cheng SH, Wong WS, Lau KM, Cheng G, Ng MH. JAK2 V617F mutation is associated with increased risk of thrombosis in Chinese patients with essential thrombocythaemia. British Journal of Haematology. 141: 902-4. PMID 18410451 DOI: 10.1111/J.1365-2141.2008.07127.X  0.562
2007 Chen L, Fong SY, Lam CW, Tang NL, Ng MH, Li AM, Ho CK, Cheng SH, Lau KM, Wing YK. The familial risk and HLA susceptibility among narcolepsy patients in Hong Kong Chinese. Sleep. 30: 851-8. PMID 17682655 DOI: 10.1093/Sleep/30.7.851  0.554
2007 Cheng SH, Ng MH, Lau KM, Liu HS, Chan JC, Hui AB, Lo KW, Jiang H, Hou J, Chu RW, Wong WS, Chan NP, Ng HK. 4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor 4. Blood. 109: 2089-99. PMID 17077331 DOI: 10.1182/Blood-2006-04-018770  0.606
2007 Wong WS, Cheng KC, Lau KM, Chan NP, Shing MM, Cheng SH, Chik KW, Li CK, Ng MH. Clonal evolution of 8p11 stem cell syndrome in a 14-year-old Chinese boy: a review of literature of t(8;13) associated myeloproliferative diseases. Leukemia Research. 31: 235-8. PMID 16777224 DOI: 10.1016/J.Leukres.2006.04.015  0.598
2004 Ng MH, Lau KM, Li L, Cheng SH, Chan WY, Hui PK, Zee B, Leung CB, Sung JJ. Association of human-leukocyte-antigen class I (B*0703) and class II (DRB1*0301) genotypes with susceptibility and resistance to the development of severe acute respiratory syndrome. The Journal of Infectious Diseases. 190: 515-8. PMID 15243926 DOI: 10.1086/421523  0.585
2004 Cheng SH, Ng MH, Tsang KS, Lau KM, Chan JC, Liu HS, Chu RW, Poon CS, Ng HK. Establishment and characterization of a cytogenetically complex Chinese multiple myeloma-derived cell line with homozygous p53 deletion and cyclin E overexpression. International Journal of Oncology. 24: 1141-8. PMID 15067335 DOI: 10.3892/Ijo.24.5.1141  0.603
2003 Ng MH, Lau KM, Wong WS, To KW, Cheng SH, Tsang KS, Chan NP, Kho BC, Lo KW, Tong JH, Lam CW, Chan JC. Alterations of RAS signalling in Chinese multiple myeloma patients: absent BRAF and rare RAS mutations, but frequent inactivation of RASSF1A by transcriptional silencing or expression of a non-functional variant transcript. British Journal of Haematology. 123: 637-45. PMID 14616967 DOI: 10.1046/J.1365-2141.2003.04664.X  0.598
2003 Ng MH, Wong N, Lau TT, Tsang KS, Cheng SH, Chan NP, Tang SH, Lei KI, Leung Y. Chromosomal aberrations of multiple myeloma in Chinese patients at diagnosis: a study by combined G-banding and multicolor spectral karyotyping. Oncology Reports. 10: 587-91. PMID 12684628 DOI: 10.3892/Or.10.3.587  0.569
2002 Chan NP, Ng MH, Cheng SH, Lee V, Tsang KS, Lau TT, Li CK. Hereditary duplication of proximal chromosome 1q (q11q22) in a patient with T lymphoblastic lymphoma/leukaemia: a family study using G banding and comparative genomic hybridisation. Journal of Medical Genetics. 39: e79. PMID 12471217 DOI: 10.1136/Jmg.39.12.E79  0.592
2001 Ng MH, Wong N, Tsang KS, Cheng SH, Chung YF, Lo KW. Recurrent chromosomal rearrangements involving breakpoints 3p21 and 19q13 in Chinese IgD multiple myeloma detected by G-banding and multicolor spectral karyotyping: a review of IgD karyotype literature. Human Pathology. 32: 1016-20. PMID 11567234 DOI: 10.1053/Hupa.2001.27122  0.583
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