| Year |
Citation |
Score |
| 2024 |
Perry ML, Varney KM, Tiwary P, Weber DJ, Hernández-Ochoa EO. Unveiling the intricate role of S100A1 in regulating RyR1 activity: A commentary on "Structural insights into the regulation of RyR1 by S100A1". Cell Calcium. 123: 102947. PMID 39226841 DOI: 10.1016/j.ceca.2024.102947 |
0.691 |
|
| 2024 |
Sevdalis SE, Varney KM, Cook ME, Gillespie JJ, Pozharski E, Weber DJ. Structural and Functional Insights into the Delivery Systems of and Clostridial Binary Toxins. Toxins. 16. PMID 39195740 DOI: 10.3390/toxins16080330 |
0.624 |
|
| 2024 |
Bhattacharya S, Varney KM, Dahmane T, Johnson BA, Weber DJ, Palmer AG. Deuterium spin relaxation of fractionally deuterated ribonuclease H using paired 475 and 950 MHz NMR spectrometers. Journal of Biomolecular Nmr. PMID 38856928 DOI: 10.1007/s10858-024-00443-w |
0.588 |
|
| 2024 |
Samanta R, Zhuang X, Varney KM, Weber DJ, Matysiak S. Deciphering S100B Allosteric Signaling: The Role of a Peptide Target, TRTK-12, as an Ensemble Modulator. Journal of Chemical Information and Modeling. PMID 38605537 DOI: 10.1021/acs.jcim.4c00116 |
0.721 |
|
| 2023 |
Lázaro-Gorines R, Pérez P, Heras-Murillo I, Adán-Barrientos I, Albericio G, Astorgano D, Flores S, Luczkowiak J, Labiod N, Harwood SL, Segura-Tudela A, Rubio-Pérez L, Nugraha Y, Shang X, Li Y, ... ... Weber DJ, et al. Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2304818. PMID 37863812 DOI: 10.1002/advs.202304818 |
0.775 |
|
| 2023 |
Abeyawardhane DL, Adipietro KA, Godoy-Ruiz R, Varney KM, Sevdalis SE, Nawaz IF, Spittel AX, Rustandi RR, Silin VI, des Georges A, Pozharski E, Weber DJ. Endosomal activation of the binary toxin is Ca -dependent. Biorxiv : the Preprint Server For Biology. PMID 37645845 DOI: 10.1101/2023.08.18.553786 |
0.818 |
|
| 2023 |
Thankan RS, Thomas E, Purushottamachar P, Weber DJ, Njar VCO. Salinization Dramatically Enhance the Anti-Prostate Cancer Efficacies of AR/AR-V7 and Mnk1/2 Molecular Glue Degraders, Galeterone and VNPP433-3β Which Outperform Docetaxel and Enzalutamide in CRPC CWR22Rv1 Xenograft Mouse Model. Bioorganic Chemistry. 139: 106700. PMID 37392559 DOI: 10.1016/j.bioorg.2023.106700 |
0.271 |
|
| 2023 |
Chen X, Adhikary G, Newland JJ, Xu W, Keillor JW, Weber DJ, Eckert RL. Transglutaminase 2 binds to the CD44v6 cytoplasmic domain to stimulate CD44v6/ERK1/2 signaling and maintain an aggressive cancer phenotype. Molecular Cancer Research : McR. PMID 37227250 DOI: 10.1158/1541-7786.MCR-23-0051 |
0.355 |
|
| 2023 |
O'Neal AJ, Singh N, Rolandelli A, Laukaitis HJ, Wang X, Shaw DK, Young BD, Narasimhan S, Dutta S, Snyder GA, Samaddar S, Marnin L, Butler LR, Mendes MT, Cabrera Paz FE, ... ... Weber DJ, et al. Croquemort elicits activation of the immune deficiency pathway in ticks. Proceedings of the National Academy of Sciences of the United States of America. 120: e2208673120. PMID 37155900 DOI: 10.1073/pnas.2208673120 |
0.298 |
|
| 2023 |
Yu W, Weber DJ, MacKerell AD. Integrated Covalent Drug Design Workflow Using Site Identification by Ligand Competitive Saturation. Journal of Chemical Theory and Computation. PMID 37115781 DOI: 10.1021/acs.jctc.3c00232 |
0.358 |
|
| 2023 |
Thomas E, Thankan RS, Purushottamachar P, Weber DJ, Njar VCO. Targeted Degradation of Androgen Receptor by VNPP433-3β in Castration-Resistant Prostate Cancer Cells Implicates Interaction with E3 Ligase MDM2 Resulting in Ubiquitin-Proteasomal Degradation. Cancers. 15. PMID 36831540 DOI: 10.3390/cancers15041198 |
0.334 |
|
| 2023 |
Karade SS, Franco EJ, Rojas AC, Hanrahan KC, Kolesnikov A, Yu W, MacKerell AD, Hill DC, Weber DJ, Brown AN, Treston AM, Mariuzza RA. Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum α-Glucosidase I with Anti-SARS-CoV-2 Activity. Journal of Medicinal Chemistry. PMID 36762932 DOI: 10.1021/acs.jmedchem.2c01750 |
0.304 |
|
| 2022 |
Coburn KM, Roth B, Varney KM, Carrier F, Weber DJ. H, C, and N assignments of the mRNA binding protein hnRNP A18. Biomolecular Nmr Assignments. PMID 36539586 DOI: 10.1007/s12104-022-10117-z |
0.796 |
|
| 2022 |
Yu W, Weber DJ, MacKerell AD. Computer-Aided Drug Design: An Update. Methods in Molecular Biology (Clifton, N.J.). 2601: 123-152. PMID 36445582 DOI: 10.1007/978-1-0716-2855-3_7 |
0.243 |
|
| 2022 |
Young BD, Cook ME, Costabile BK, Samanta R, Zhuang X, Sevdalis SE, Varney KM, Mancia F, Matysiak S, Lattman E, Weber DJ. Binding and Functional Folding (BFF): A Physiological Framework for Studying Biomolecular Interactions and Allostery. Journal of Molecular Biology. 167872. PMID 36354074 DOI: 10.1016/j.jmb.2022.167872 |
0.738 |
|
| 2022 |
Thomas E, Thankan RS, Purushottamachar P, Huang W, Kane MA, Zhang Y, Ambulos NP, Weber DJ, Njar VCO. Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3β: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant Prostate Cancer In Vitro and In Vivo Models. Cells. 11. PMID 36078112 DOI: 10.3390/cells11172699 |
0.273 |
|
| 2022 |
Thomas E, Thankan RS, Purushottamachar P, Huang W, Kane MA, Zhang Y, Ambulos N, Weber DJ, Njar VCO. Transcriptome profiling reveals that VNPP433-3β, the lead next-generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial-mesenchymal transition and stem cell markers. Molecular Carcinogenesis. PMID 35512605 DOI: 10.1002/mc.23406 |
0.252 |
|
| 2021 |
Chowdhury A, Marin A, Weber DJ, Andrianov AK. Nano-Assembly of Quisinostat and Biodegradable Macromolecular Carrier Results in Supramolecular Complexes with Slow-Release Capabilities. Pharmaceutics. 13. PMID 34834249 DOI: 10.3390/pharmaceutics13111834 |
0.283 |
|
| 2021 |
Rorke EA, Adhikary G, Szmacinski H, Lakowicz JR, Weber DJ, Godoy-Ruiz R, Puranik P, Keillor JW, Gates EWJ, Eckert RL. Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity. Molecular Carcinogenesis. PMID 34610184 DOI: 10.1002/mc.23356 |
0.386 |
|
| 2021 |
Young BD, Varney KM, Wilder PT, Costabile BK, Pozharski E, Cook ME, Godoy-Ruiz R, Clarke OB, Mancia F, Weber DJ. Physiologically Relevant Free Ca Ion Concentrations Regulate STRA6-Calmodulin Complex Formation via the BP2 Region of STRA6. Journal of Molecular Biology. 433: 167272. PMID 34592217 DOI: 10.1016/j.jmb.2021.167272 |
0.799 |
|
| 2021 |
Alasady MJ, Terry AR, Pierce AD, Cavalier MC, Blaha CS, Adipietro KA, Wilder PT, Weber DJ, Hay N. The calcium-binding protein S100B reduces IL6 production in malignant melanoma via inhibition of RSK cellular signaling. Plos One. 16: e0256238. PMID 34411141 DOI: 10.1371/journal.pone.0256238 |
0.781 |
|
| 2021 |
Kundu N, Ma X, Hoag S, Wang F, Ibrahim A, Godoy-Ruiz R, Weber DJ, Fulton AM. An Extract of Taro () Mediates Potent Inhibitory Actions on Metastatic and Cancer Stem Cells by Tumor Cell-Autonomous and Immune-Dependent Mechanisms. Breast Cancer : Basic and Clinical Research. 15: 11782234211034937. PMID 34376983 DOI: 10.1177/11782234211034937 |
0.266 |
|
| 2021 |
Roth BM, DePalma RM, Cook ME, Varney KM, Weber DJ, Ogretmen B. H, C, and N backbone resonance assignments of the SET/TAF-1β/I2PP2A oncoprotein (residues 23-225). Biomolecular Nmr Assignments. PMID 34156643 DOI: 10.1007/s12104-021-10034-7 |
0.808 |
|
| 2021 |
Abeyawardhane DL, Godoy-Ruiz R, Adipietro KA, Varney KM, Rustandi RR, Pozharski E, Weber DJ. The Importance of Therapeutically Targeting the Binary Toxin from . International Journal of Molecular Sciences. 22. PMID 33805767 DOI: 10.3390/ijms22062926 |
0.778 |
|
| 2021 |
Chen Y, Toth EA, Ruan B, Choi EJ, Simmerman R, Chen Y, He Y, Wang R, Godoy-Ruiz R, King H, Custer G, Travis Gallagher D, Rozak DA, Solomon M, Muro S, ... Weber DJ, et al. Engineering subtilisin proteases that specifically degrade active RAS. Communications Biology. 4: 299. PMID 33674772 DOI: 10.1038/s42003-021-01818-7 |
0.278 |
|
| 2021 |
Young BD, Yu W, Rodríguez DJV, Varney KM, MacKerell AD, Weber DJ. Specificity of Molecular Fragments Binding to S100B versus S100A1 as Identified by NMR and Site Identification by Ligand Competitive Saturation (SILCS). Molecules (Basel, Switzerland). 26. PMID 33450915 DOI: 10.3390/molecules26020381 |
0.735 |
|
| 2021 |
Solano-Gonzalez E, Coburn KM, Yu W, Wilson GM, Nurmemmedov E, Kesari S, Chang ET, MacKerell AD, Weber DJ, Carrier F. Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint. Nucleic Acids Research. PMID 33398344 DOI: 10.1093/nar/gkaa1254 |
0.346 |
|
| 2020 |
Cook ME, Varney KM, Godoy-Ruiz R, Weber DJ. H, C, and N resonance assignments of the Clostridioides difficile receptor binding domain 2 (CDTb, residues 757-876). Biomolecular Nmr Assignments. PMID 33034833 DOI: 10.1007/s12104-020-09979-y |
0.69 |
|
| 2020 |
Varney KM, Wilder PT, Godoy-Ruiz R, Mancia F, Weber DJ. Correction to: H, C, and N resonance assignments of human calmodulin bound to a peptide derived from the STRA6 vitamin A transporter (CaMBP2). Biomolecular Nmr Assignments. PMID 32248334 DOI: 10.1007/s12104-020-09942-x |
0.741 |
|
| 2020 |
Xu X, Godoy-Ruiz R, Adipietro KA, Peralta C, Ben-Hail D, Varney KM, Cook ME, Roth BM, Wilder PT, Cleveland T, Grishaev A, Neu HM, Michel SLJ, Yu W, Beckett D, ... ... Weber DJ, et al. Structure of the cell-binding component of the binary toxin reveals a di-heptamer macromolecular assembly. Proceedings of the National Academy of Sciences of the United States of America. PMID 31896582 DOI: 10.1073/Pnas.1919490117 |
0.812 |
|
| 2020 |
Costabile BK, Chen Y, Kim J, Kim Y, Clarke OB, Wilder PT, Weber DJ, Quadro L, Sun H, Mancia F. Investigating the Mechanism of STRA6-Mediated Cellular Retinol Uptake Biophysical Journal. 118: 93a. DOI: 10.1016/J.Bpj.2019.11.672 |
0.621 |
|
| 2020 |
Coburn K, Solano-Gonzalez E, Roth B, Wilder PT, Varney K, Carrier F, Weber DJ. Investigation of the Impact of Post-Translational Modifications of HNRNP A18 on Small Molecule Inhibitors Biophysical Journal. 118: 49a. DOI: 10.1016/J.Bpj.2019.11.450 |
0.765 |
|
| 2019 |
Kwegyir-Afful AK, Ramalingam S, Ramamurthy VP, Purushottamachar P, Murigi FN, Vasaitis TS, Huang W, Kane MA, Zhang Y, Ambulos N, Tiwari S, Srivastava P, Nnane IP, Hussain A, Qiu Y, ... Weber DJ, et al. Galeterone and The Next Generation Galeterone Analogs, VNPP414 and VNPP433-3β Exert Potent Therapeutic Effects in Castration-/Drug-Resistant Prostate Cancer Preclinical Models In Vitro and In Vivo. Cancers. 11. PMID 31653008 DOI: 10.3390/Cancers11111637 |
0.366 |
|
| 2019 |
Varney KM, Cook ME, Weber DJ. An asymmetry that leads to activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31427532 DOI: 10.1073/Pnas.1912729116 |
0.648 |
|
| 2019 |
Donohue E, Khorsand S, Mercado G, Varney KM, Wilder PT, Yu W, MacKerell AD, Alexander P, Van QN, Moree B, Stephen AG, Weber DJ, Salafsky J, McCormick F. Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder. Proceedings of the National Academy of Sciences of the United States of America. PMID 31399543 DOI: 10.1073/Pnas.1905516116 |
0.786 |
|
| 2019 |
Deredge D, Wintrode PL, Tulapurkar ME, Nagarsekar A, Zhang Y, Weber DJ, Shapiro P, Hasday JD. A temperature-dependent conformational shift in p38α MAP kinase substrate binding region associated with changes in substrate phosphorylation profile. The Journal of Biological Chemistry. PMID 31213525 DOI: 10.1074/Jbc.Ra119.007525 |
0.438 |
|
| 2019 |
Roth BM, Varney KM, Yang H, Weber DJ, Tomkinson AE. H, C, and N backbone resonance assignments of the human DNA ligase 3 DNA-binding domain (residues 257-477). Biomolecular Nmr Assignments. PMID 31093909 DOI: 10.1007/S12104-019-09896-9 |
0.776 |
|
| 2019 |
Bester SM, Adipietro KA, Funk VL, Myslinski J, Keul ND, Cheung J, Wilder PT, Wood ZA, Weber DJ, Height JJ, Pegan SD. The structural and biochemical impact of monomerizing human acetylcholinesterase. Protein Science : a Publication of the Protein Society. PMID 30993792 DOI: 10.1002/Pro.3625 |
0.673 |
|
| 2019 |
Varney KM, Wilder PT, Godoy-Ruiz R, Mancia F, Weber DJ. HC, and N resonance assignments of human calmodulin bound to a peptide derived from the STRA6 vitamin A transporter (CaMBP2). Biomolecular Nmr Assignments. PMID 30875027 DOI: 10.1007/S12104-019-09890-1 |
0.802 |
|
| 2019 |
Wilder PT, Varney KM, Weber DJ. Targeting S100 Calcium-Binding Proteins with Small Molecule Inhibitors. Methods in Molecular Biology (Clifton, N.J.). 1929: 291-310. PMID 30710281 DOI: 10.1007/978-1-4939-9030-6_19 |
0.79 |
|
| 2019 |
Cook M, Varney K, Godoy-Ruiz R, Weber D. 1H 15N 13C Resonance Assignments of Receptor Binding Domain 1 of CDTb Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr28050 |
0.681 |
|
| 2019 |
Yu W, Pozharskiy E, Varney K, Weber DJ, MacKerell AD. Development of Small Molecule Inhibitors Targeting Clostridium Difficile Binary Toxin using the Site-Identification by Ligand Competitive Saturation (SILCS) Method Biophysical Journal. 116: 482a. DOI: 10.1016/J.Bpj.2018.11.2604 |
0.679 |
|
| 2018 |
Yu W, Jo S, Lakkaraju SK, Weber DJ, MacKerell AD. Exploring protein-protein interactions using the Site-Identification by Ligand Competitive Saturation (SILCS) methodology. Proteins. PMID 30582220 DOI: 10.1002/Prot.25650 |
0.439 |
|
| 2018 |
Hernández-Ochoa EO, Melville Z, Vanegas C, Varney KM, Wilder PT, Melzer W, Weber DJ, Schneider MF. Loss of S100A1 expression leads to Ca release potentiation in mutant mice with disrupted CaM and S100A1 binding to CaMBD2 of RyR1. Physiological Reports. 6: e13822. PMID 30101473 DOI: 10.14814/Phy2.13822 |
0.826 |
|
| 2017 |
Wilder PT, Weber DJ, Winstead A, Parnell S, Hinton TV, Stevenson M, Giri D, Azemati S, Olczak P, Powell BV, Odebode T, Tadesse S, Zhang Y, Pramanik SK, Wachira JM, et al. Unprecedented anticancer activities of organorhenium sulfonato and carboxylato complexes against hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells. Molecular and Cellular Biochemistry. PMID 28913709 DOI: 10.1007/S11010-017-3181-Z |
0.681 |
|
| 2017 |
Melville Z, Hernandez-Ochoa EO, Pratt SJ, Liu Y, Pierce AD, Wilder PT, Adipietro KA, Breysse DH, Varney K, Schneider MF, Weber DJ. The activation of PKA by the calcium-binding protein S100A1 is independent of cyclic AMP. Biochemistry. PMID 28409622 DOI: 10.1021/Acs.Biochem.7B00117 |
0.826 |
|
| 2017 |
Melville Z, Aligholizadeh E, McKnight LE, Weber DJ, Pozharski E, Weber DJ. X-ray crystal structure of human calcium-bound S100A1. Acta Crystallographica. Section F, Structural Biology Communications. 73: 215-221. PMID 28368280 DOI: 10.1107/S2053230X17003983 |
0.821 |
|
| 2017 |
Coburn K, Melville Z, Aligholizadeh E, Roth BM, Varney KM, Carrier F, Pozharski E, Weber DJ. Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Acta Crystallographica. Section F, Structural Biology Communications. 73: 209-214. PMID 28368279 DOI: 10.1107/S2053230X17003454 |
0.787 |
|
| 2017 |
Alasady MJ, Adipietro KA, Pierce AD, Wilder PT, Hartman KG, Weber DJ, Hay N. Abstract 315: S100B regulates IL-6 signaling via the p90 ribosomal S6 kinase (RSK) in malignant melanoma Cancer Research. 77: 315-315. DOI: 10.1158/1538-7445.Am2017-315 |
0.766 |
|
| 2017 |
Banerjee HN, Hodge S, Kahan W, Mandal S, Weber D, Lapidus R, Sarkar F, Ghosh S. Abstract 120: A study of in vitro and in vivo effects of a novel peptide and rhenium compounds on prostate cancer Cancer Research. 77: 120-120. DOI: 10.1158/1538-7445.Am2017-120 |
0.383 |
|
| 2016 |
Kerr C, Szmacinski H, Fisher ML, Nance B, Lakowicz JR, Akbar A, Keillor JW, Lok Wong T, Godoy-Ruiz R, Toth EA, Weber DJ, Eckert RL. Transamidase site-targeted agents alter the conformation of the transglutaminase cancer stem cell survival protein to reduce GTP binding activity and cancer stem cell survival. Oncogene. PMID 27941875 DOI: 10.1038/Onc.2016.452 |
0.503 |
|
| 2016 |
Chen Y, Clarke OB, Kim J, Stowe S, Kim YK, Assur Z, Cavalier M, Godoy-Ruiz R, von Alpen DC, Manzini C, Blaner WS, Frank J, Quadro L, Weber DJ, Shapiro L, et al. Structure of the STRA6 receptor for retinol uptake. Science (New York, N.Y.). 353. PMID 27563101 DOI: 10.1126/Science.Aad8266 |
0.79 |
|
| 2016 |
Roth BM, Varney KM, Rustandi RR, Weber DJ. (1)H(N), (13)C, and (15)N resonance assignments of the CDTb-interacting domain (CDTaBID) from the Clostridium difficile binary toxin catalytic component (CDTa, residues 1-221). Biomolecular Nmr Assignments. PMID 27351891 DOI: 10.1007/S12104-016-9695-6 |
0.793 |
|
| 2016 |
Cavalier MC, Melville Z, Aligholizadeh E, Raman EP, Yu W, Fang L, Alasady M, Pierce AD, Wilder PT, MacKerell AD, Weber DJ. Novel protein-inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography. Acta Crystallographica. Section D, Structural Biology. 72: 753-760. PMID 27303795 DOI: 10.1107/S2059798316005532 |
0.815 |
|
| 2016 |
Roth BM, Godoy-Ruiz R, Varney KM, Rustandi RR, Weber DJ. (1)H, (13)C, and (15)N resonance assignments of an enzymatically active domain from the catalytic component (CDTa, residues 216-420) of a binary toxin from Clostridium difficile. Biomolecular Nmr Assignments. PMID 26886352 DOI: 10.1007/S12104-016-9669-8 |
0.794 |
|
| 2016 |
Cavalier MC, Ansari MI, Pierce AD, Wilder PT, McKnight LE, Raman EP, Neau DB, Bezawada P, Alasady MJ, Charpentier TH, Varney K, Toth EA, MacKerell AD, Coop A, Weber DJ. Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations. Journal of Medicinal Chemistry. PMID 26727270 DOI: 10.1021/Acs.Jmedchem.5B01369 |
0.811 |
|
| 2016 |
Cavalier MC, Wilder PT, Luci D, Maloney DJ, Fang L, Ansari MI, MacKerell AD, Coop A, Jadhav A, Weber DJ. Abstract 1358: Structure-based drug design of 3-site binding, high affinity inhibitors of S100B in malignant melanoma Cancer Research. 76: 1358-1358. DOI: 10.1158/1538-7445.Am2016-1358 |
0.81 |
|
| 2016 |
Hernández-Ochoa EO, Cannon BR, Vanegas C, Weber DJ, Schneider MF. Inactivation of Cav1.1 Channels in Adult Skeletal Muscle: Effects of a C-Terminal Pre-IQ Mutation Biophysical Journal. 110: 98a. DOI: 10.1016/J.Bpj.2015.11.590 |
0.778 |
|
| 2015 |
Mei Y, Wang Y, Kumari P, Shetty AC, Clark D, Gable T, MacKerell AD, Ma MZ, Weber DJ, Yang AJ, Edelman MJ, Mao L. A piRNA-like small RNA interacts with and modulates p-ERM proteins in human somatic cells. Nature Communications. 6: 7316. PMID 26095918 DOI: 10.1038/Ncomms8316 |
0.428 |
|
| 2015 |
Bresnick AR, Weber DJ, Zimmer DB. S100 proteins in cancer. Nature Reviews. Cancer. 15: 96-109. PMID 25614008 DOI: 10.1038/Nrc3893 |
0.434 |
|
| 2015 |
Stowe SD, Cavalier MC, Godoy-Ruiz R, Varney KJ, Wilder PT, Gartenhaus RB, Weber DJ. Abstract 2454: Targeting the translational enhancer complex MCT-1:DenR to disrupt NHL survival Cancer Research. 75: 2454-2454. DOI: 10.1158/1538-7445.Am2015-2454 |
0.79 |
|
| 2015 |
Melville Z, Varney K, Cavalier M, Stowe S, Weber D, Toth E, Weber D. Characterizing a New Metal Binding Site in S100B Biophysical Journal. 108: 48a. DOI: 10.1016/J.Bpj.2014.11.293 |
0.825 |
|
| 2015 |
Stowe SD, Cavalier MC, Godoy-Ruiz R, Varney KM, Wilder PT, Gartenhaus RB, Weber DJ. Characterizing the MCT-1:DenR Complex, a Translational Enhancer for Lymphoma Survival Biophysical Journal. 108: 219a. DOI: 10.1016/J.Bpj.2014.11.1212 |
0.791 |
|
| 2015 |
Cavalier MC, Weber DJ. Targeting Melanoma with Small Molecules: Inhibitors of the Calcium-Binding Protein S100B Biophysical Journal. 108: 214a. DOI: 10.1016/J.Bpj.2014.11.1181 |
0.815 |
|
| 2014 |
Cavalier MC, Pierce AD, Wilder PT, Alasady MJ, Hartman KG, Neau DB, Foley TL, Jadhav A, Maloney DJ, Simeonov A, Toth EA, Weber DJ. Covalent small molecule inhibitors of Ca(2+)-bound S100B. Biochemistry. 53: 6628-40. PMID 25268459 DOI: 10.1021/Bi5005552 |
0.825 |
|
| 2014 |
Gu H, Mickler EA, Cummings OW, Sandusky GE, Weber DJ, Gracon A, Woodruff T, Wilkes DS, Vittal R. Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4223-34. PMID 24958208 DOI: 10.1096/Fj.13-247650 |
0.344 |
|
| 2014 |
Dhar A, Mallick S, Ghosh P, Maiti A, Ahmed I, Bhattacharya S, Mandal T, Manna A, Roy K, Singh S, Nayak DK, Wilder PT, Markowitz J, Weber D, Ghosh MK, et al. Simultaneous inhibition of key growth pathways in melanoma cells and tumor regression by a designed bidentate constrained helical peptide. Biopolymers. 101: 344-58. PMID 24839139 DOI: 10.1002/Bip.22505 |
0.698 |
|
| 2014 |
Hartman KG, Vitolo MI, Pierce AD, Fox JM, Shapiro P, Martin SS, Wilder PT, Weber DJ. Complex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSK. The Journal of Biological Chemistry. 289: 12886-95. PMID 24627490 DOI: 10.1074/Jbc.M114.561613 |
0.803 |
|
| 2014 |
Mazalouskas MD, Godoy-Ruiz R, Weber DJ, Zimmer DB, Honkanen RE, Wadzinski BE. Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1. The Journal of Biological Chemistry. 289: 4219-32. PMID 24371145 DOI: 10.1074/Jbc.M113.518514 |
0.426 |
|
| 2013 |
Ramagopal UA, Dulyaninova NG, Varney KM, Wilder PT, Nallamsetty S, Brenowitz M, Weber DJ, Almo SC, Bresnick AR. Structure of the S100A4/myosin-IIA complex. Bmc Structural Biology. 13: 31. PMID 24252706 DOI: 10.1186/1472-6807-13-31 |
0.808 |
|
| 2013 |
Zimmer DB, Lapidus RG, Weber DJ. In vivo screening of S100B inhibitors for melanoma therapy. Methods in Molecular Biology (Clifton, N.J.). 963: 303-17. PMID 23296618 DOI: 10.1007/978-1-62703-230-8_18 |
0.437 |
|
| 2013 |
Hartman KG, McKnight LE, Liriano MA, Weber DJ. The evolution of S100B inhibitors for the treatment of malignant melanoma. Future Medicinal Chemistry. 5: 97-109. PMID 23256816 DOI: 10.4155/Fmc.12.191 |
0.799 |
|
| 2013 |
Donato R, Cannon BR, Sorci G, Riuzzi F, Hsu K, Weber DJ, Geczy CL. Functions of S100 proteins. Current Molecular Medicine. 13: 24-57. PMID 22834835 |
0.719 |
|
| 2013 |
Pierce AD, Hartman KG, Weber D. Abstract 5243: The novel calcium-dependent direct binding of S100B to p90 ribosomal S6 kinase (RSK) decreases MAP kinase-mediated RSK activation in malignant melanoma. Cancer Research. 73: 5243-5243. DOI: 10.1158/1538-7445.Am2013-5243 |
0.825 |
|
| 2013 |
Cavalier MC, McKnight L, Weber D, Wilder P. Abstract 2226: Structure/function characterization of SBi4225, a novel inhibitor of the calcium-binding protein S100B. Cancer Research. 73: 2226-2226. DOI: 10.1158/1538-7445.Am2013-2226 |
0.825 |
|
| 2013 |
Cavalier M, Wilder PT, Coop A, MacKerell A, Weber DJ. Abstract B103: Inhibitors of S100B (SBiXs) in malignant melanoma. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B103 |
0.813 |
|
| 2012 |
McKnight LE, Raman EP, Bezawada P, Kudrimoti S, Wilder PT, Hartman KG, Godoy-Ruiz R, Toth EA, Coop A, Mackerell AD, Weber DJ. Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B. Acs Medicinal Chemistry Letters. 3: 975-979. PMID 23264854 DOI: 10.1021/Ml300166S |
0.818 |
|
| 2012 |
Liriano MA, Varney KM, Wright NT, Hoffman CL, Toth EA, Ishima R, Weber DJ. Target binding to S100B reduces dynamic properties and increases Ca(2+)-binding affinity for wild type and EF-hand mutant proteins. Journal of Molecular Biology. 423: 365-85. PMID 22824086 DOI: 10.1016/J.Jmb.2012.07.011 |
0.814 |
|
| 2012 |
Hartman KG, Vitolo MI, Wilder PT, Fox J, Shapiro P, Martin SS, Weber DJ. Abstract 2164: S100B affects MAPK signaling in malignant melanoma via a direct interaction with RSK Cancer Research. 72: 2164-2164. DOI: 10.1158/1538-7445.Am2012-2164 |
0.799 |
|
| 2011 |
Cannon BR, Zimmer DB, Weber DJ. S100A1 (S100 calcium binding protein A1). Atlas of Genetics and Cytogenetics in Oncology and Haematology. 15: 873-876. PMID 26213580 DOI: 10.4267/2042/46035 |
0.744 |
|
| 2011 |
Xu Z, Chen YW, Battu A, Wilder P, Weber D, Yu W, Mackerell AD, Chen LM, Chai KX, Johnson MD, Lin CY. Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade. Journal of Medicinal Chemistry. 54: 7567-78. PMID 21966950 DOI: 10.1021/Jm200920S |
0.666 |
|
| 2011 |
House RP, Pozzuto M, Patel P, Dulyaninova NG, Li ZH, Zencheck WD, Vitolo MI, Weber DJ, Bresnick AR. Two functional S100A4 monomers are necessary for regulating nonmuscle myosin-IIA and HCT116 cell invasion. Biochemistry. 50: 6920-32. PMID 21721535 DOI: 10.1021/Bi200498Q |
0.7 |
|
| 2011 |
Yamaguchi N, Prosser BL, Ghassemi F, Xu L, Pasek DA, Eu JP, Hernández-Ochoa EO, Cannon BR, Wilder PT, Lovering RM, Weber D, Melzer W, Schneider MF, Meissner G. Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1. American Journal of Physiology. Cell Physiology. 300: C998-C1012. PMID 21289290 DOI: 10.1152/Ajpcell.00370.2010 |
0.803 |
|
| 2011 |
Liriano M, Varney KM, Ishima R, Weber DJ. Abstract 2328: 15N-backbone and side-chain dynamics of the mutant calcium-binding protein S100B D63N Cancer Research. 71: 2328-2328. DOI: 10.1158/1538-7445.Am2011-2328 |
0.743 |
|
| 2011 |
Wilder PT, Gianni K, Green DL, Weber DJ. Abstract 1372: A cell based high throughput screening assay for inhibitors of melanoma with high S100B Cancer Research. 71: 1372-1372. DOI: 10.1158/1538-7445.Am2011-1372 |
0.682 |
|
| 2011 |
Gianni K, Vitolo MI, Wilder PT, Martin SS, Weber DJ. Abstract 1054: S100B affects cell signaling in malignant melanoma Cancer Research. 71: 1054-1054. DOI: 10.1158/1538-7445.Am2011-1054 |
0.768 |
|
| 2011 |
Cannon B, Hernández-Ochoa E, Varney K, Schneider M, Weber D. The Interaction of S100a1 with Type-2b Regulatory Subunit of Protein Kinase A Biophysical Journal. 100: 86a. DOI: 10.1016/J.Bpj.2010.12.675 |
0.787 |
|
| 2010 |
Wilder PT, Charpentier TH, Liriano MA, Gianni K, Varney KM, Pozharski E, Coop A, Toth EA, Mackerell AD, Weber DJ. In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction. International Journal of High Throughput Screening. 2010: 109-126. PMID 21132089 DOI: 10.2147/IJHTS.S8210 |
0.813 |
|
| 2010 |
Zimmer DB, Weber DJ. The Calcium-Dependent Interaction of S100B with Its Protein Targets. Cardiovascular Psychiatry and Neurology. 2010. PMID 20827422 DOI: 10.1155/2010/728052 |
0.546 |
|
| 2010 |
Lin J, Yang Q, Wilder PT, Carrier F, Weber DJ. The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma. The Journal of Biological Chemistry. 285: 27487-98. PMID 20587415 DOI: 10.1074/Jbc.M110.155382 |
0.734 |
|
| 2010 |
Weiss MB, Vitolo MI, Mohseni M, Rosen DM, Denmeade SR, Park BH, Weber DJ, Bachman KE. Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic response. Oncogene. 29: 4715-24. PMID 20562907 DOI: 10.1038/Onc.2010.220 |
0.716 |
|
| 2010 |
Malashkevich VN, Dulyaninova NG, Ramagopal UA, Liriano MA, Varney KM, Knight D, Brenowitz M, Weber DJ, Almo SC, Bresnick AR. Phenothiazines inhibit S100A4 function by inducing protein oligomerization. Proceedings of the National Academy of Sciences of the United States of America. 107: 8605-10. PMID 20421509 DOI: 10.1073/Pnas.0913660107 |
0.842 |
|
| 2010 |
Gilquin B, Cannon BR, Hubstenberger A, Moulouel B, Falk E, Merle N, Assard N, Kieffer S, Rousseau D, Wilder PT, Weber DJ, Baudier J. The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A. Molecular and Cellular Biology. 30: 2724-36. PMID 20351179 DOI: 10.1128/Mcb.01468-09 |
0.822 |
|
| 2010 |
Charpentier TH, Thompson LE, Liriano MA, Varney KM, Wilder PT, Pozharski E, Toth EA, Weber DJ. The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography. Journal of Molecular Biology. 396: 1227-43. PMID 20053360 DOI: 10.1016/J.Jmb.2009.12.057 |
0.834 |
|
| 2010 |
Smith J, Stewart BJ, Glaysher S, Peregrin K, Knight LA, Weber DJ, Cree IA. The effect of pentamidine on melanoma ex vivo. Anti-Cancer Drugs. 21: 181-5. PMID 19966562 DOI: 10.1097/CAD.0b013e3283340cee |
0.334 |
|
| 2010 |
Mehnert JM, Hausner PF, Tan M, Weber D, Sausville EA. Treatment of melanoma with wild-type p53 (wtp53) and detectable S100B using pentamidine: A phase II trial with correlative biomarker endpoints. Journal of Clinical Oncology. 28: TPS310-TPS310. DOI: 10.1200/Jco.2010.28.15_Suppl.Tps310 |
0.482 |
|
| 2010 |
Gianni K, Wilder PT, Vitolo MI, Shapiro P, Weber DJ. Abstract 4125: The effects of S100B on cell signaling in malignant melanoma Cancer Research. 70: 4125-4125. DOI: 10.1158/1538-7445.Am10-4125 |
0.777 |
|
| 2009 |
Wright NT, Cannon BR, Zimmer DB, Weber DJ. S100A1: Structure, Function, and Therapeutic Potential. Current Chemical Biology. 3: 138-145. PMID 19890475 DOI: 10.2174/187231309788166460 |
0.816 |
|
| 2009 |
Vitolo MI, Weiss MB, Szmacinski M, Tahir K, Waldman T, Park BH, Martin SS, Weber DJ, Bachman KE. Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells. Cancer Research. 69: 8275-83. PMID 19843859 DOI: 10.1158/0008-5472.Can-09-1067 |
0.724 |
|
| 2009 |
Hernández-Ochoa EO, Prosser BL, Wright NT, Contreras M, Weber DJ, Schneider MF. Augmentation of Cav1 channel current and action potential duration after uptake of S100A1 in sympathetic ganglion neurons. American Journal of Physiology. Cell Physiology. 297: C955-70. PMID 19657060 DOI: 10.1152/Ajpcell.00140.2009 |
0.652 |
|
| 2009 |
Charpentier TH, Wilder PT, Liriano MA, Varney KM, Zhong S, Coop A, Pozharski E, MacKerell AD, Toth EA, Weber DJ. Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography. Biochemistry. 48: 6202-12. PMID 19469484 DOI: 10.1021/Bi9005754 |
0.839 |
|
| 2009 |
Wright NT, Cannon BR, Wilder PT, Morgan MT, Varney KM, Zimmer DB, Weber DJ. Solution structure of S100A1 bound to the CapZ peptide (TRTK12). Journal of Molecular Biology. 386: 1265-77. PMID 19452629 DOI: 10.1016/J.Jmb.2009.01.022 |
0.835 |
|
| 2009 |
Wright NT, Varney KM, Cannon BR, Morgan M, Weber DJ. Ca-S100A1 interacting with TRTK12 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kbm/Pdb |
0.768 |
|
| 2009 |
Hernández-Ochoa EO, Prosser BL, Wright NT, Contreras M, Weber DJ, Schneider MF. Uptake Of S100A1 And Augmentation Of Cav1 Channel Current And Action Potential Duration In Sympathetic Ganglion Neurons Biophysical Journal. 96: 173a. DOI: 10.1016/J.Bpj.2008.12.802 |
0.632 |
|
| 2008 |
Matthews MM, Weber DJ, Shapiro PS, Coop A, Mackerell AD. Inhibition of protein-protein interactions with low molecular weight compounds. Current Trends in Medicinal Chemistry. 5: 21-32. PMID 21927717 |
0.368 |
|
| 2008 |
Wright NT, Inman KG, Levine JA, Cannon BR, Varney KM, Weber DJ. Refinement of the solution structure and dynamic properties of Ca(2+)-bound rat S100B. Journal of Biomolecular Nmr. 42: 279-86. PMID 18949447 DOI: 10.1007/S10858-008-9282-Y |
0.826 |
|
| 2008 |
Wright NT, Prosser BL, Varney KM, Zimmer DB, Schneider MF, Weber DJ. S100A1 and calmodulin compete for the same binding site on ryanodine receptor. The Journal of Biological Chemistry. 283: 26676-83. PMID 18650434 DOI: 10.1074/Jbc.M804432200 |
0.805 |
|
| 2008 |
Charpentier TH, Wilder PT, Liriano MA, Varney KM, Pozharski E, MacKerell AD, Coop A, Toth EA, Weber DJ. Divalent metal ion complexes of S100B in the absence and presence of pentamidine. Journal of Molecular Biology. 382: 56-73. PMID 18602402 DOI: 10.1016/J.Jmb.2008.06.047 |
0.817 |
|
| 2008 |
Malashkevich VN, Varney KM, Garrett SC, Wilder PT, Knight D, Charpentier TH, Ramagopal UA, Almo SC, Weber DJ, Bresnick AR. Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA. Biochemistry. 47: 5111-26. PMID 18410126 DOI: 10.1021/Bi702537S |
0.839 |
|
| 2008 |
Prosser BL, Wright NT, Hernãndez-Ochoa EO, Varney KM, Liu Y, Olojo RO, Zimmer DB, Weber DJ, Schneider MF. S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling. The Journal of Biological Chemistry. 283: 5046-57. PMID 18089560 DOI: 10.1074/Jbc.M709231200 |
0.789 |
|
| 2008 |
Rifat D, Wright NT, Varney KM, Weber DJ, Black LW. Restriction endonuclease inhibitor IPI* of bacteriophage T4: a novel structure for a dedicated target. Journal of Molecular Biology. 375: 720-34. PMID 18037438 DOI: 10.1016/J.Jmb.2007.10.064 |
0.761 |
|
| 2007 |
Blaustein MP, Charpentier TH, Weber DJ. Getting a grip on calcium regulation. Proceedings of the National Academy of Sciences of the United States of America. 104: 18349-50. PMID 18003903 DOI: 10.1073/Pnas.0709008104 |
0.783 |
|
| 2007 |
Velarde JJ, Varney KM, Inman KG, Farfan M, Dudley E, Fletcher J, Weber DJ, Nataro JP. Solution structure of the novel dispersin protein of enteroaggregative Escherichia coli. Molecular Microbiology. 66: 1123-35. PMID 17986189 DOI: 10.1111/J.1365-2958.2007.05985.X |
0.78 |
|
| 2007 |
Markowitz J, MacKerell AD, Weber DJ. A search for inhibitors of S100B, a member of the S100 family of calcium-binding proteins. Mini Reviews in Medicinal Chemistry. 7: 609-16. PMID 17584159 DOI: 10.2174/138955707780859422 |
0.493 |
|
| 2007 |
Wilder PT, Charpentier TH, Weber DJ. Hydrocarbon-stapled helices: a novel approach for blocking protein-protein interactions. Chemmedchem. 2: 1149-51. PMID 17554748 DOI: 10.1002/Cmdc.200700102 |
0.787 |
|
| 2007 |
Charpentier TH, Wilder PT, Varney KM, Toth EA, Weber DJ. The 3D structures of Ca 2+ ‐S100B in Zn 2+ ‐ and pentamidine‐bound complexes as determined by X‐ray crystallography The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A630-A |
0.798 |
|
| 2007 |
Lin J, Carrier F, Weber DJ. The calcium‐binding protein S100B inhibits UV‐induced p53 dependent apoptosis in malignant melanoma The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A619-D |
0.504 |
|
| 2006 |
Wilder PT, Lin J, Bair CL, Charpentier TH, Yang D, Liriano M, Varney KM, Lee A, Oppenheim AB, Adhya S, Carrier F, Weber DJ. Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B. Biochimica Et Biophysica Acta. 1763: 1284-97. PMID 17010455 DOI: 10.1016/J.Bbamcr.2006.08.024 |
0.815 |
|
| 2006 |
Song H, Lee MY, Kinsey SP, Weber DJ, Blaustein MP. An N-terminal sequence targets and tethers Na+ pump alpha2 subunits to specialized plasma membrane microdomains. The Journal of Biological Chemistry. 281: 12929-40. PMID 16524882 DOI: 10.1074/Jbc.M507450200 |
0.346 |
|
| 2006 |
Yang R, Weber DJ, Carrier F. Post-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18. Nucleic Acids Research. 34: 1224-36. PMID 16513844 DOI: 10.1093/Nar/Gkj519 |
0.573 |
|
| 2006 |
Garrett SC, Varney KM, Weber DJ, Bresnick AR. S100A4, a mediator of metastasis. The Journal of Biological Chemistry. 281: 677-80. PMID 16243835 DOI: 10.1074/Jbc.R500017200 |
0.64 |
|
| 2005 |
Markowitz J, Mackerell AD, Carrier F, Charpentier TH, Weber DJ. Design of Inhibitors for S100B. Current Topics in Medicinal Chemistry. 5: 1093-108. PMID 16248785 DOI: 10.2174/156802605774370865 |
0.787 |
|
| 2005 |
Wright NT, Margolis JW, Margolis FL, Weber DJ. Refinement of the solution structure of rat olfactory marker protein (OMP). Journal of Biomolecular Nmr. 33: 63-8. PMID 16222559 DOI: 10.1007/S10858-005-1281-7 |
0.59 |
|
| 2005 |
Wright NT, Varney KM, Ellis KC, Markowitz J, Gitti RK, Zimmer DB, Weber DJ. The three-dimensional solution structure of Ca(2+)-bound S100A1 as determined by NMR spectroscopy. Journal of Molecular Biology. 353: 410-26. PMID 16169012 DOI: 10.1016/J.Jmb.2005.08.027 |
0.83 |
|
| 2005 |
Gitti RK, Wright NT, Margolis JW, Varney KM, Weber DJ, Margolis FL. Backbone dynamics of the olfactory marker protein as studied by 15N NMR relaxation measurements. Biochemistry. 44: 9673-9. PMID 16008352 DOI: 10.1021/Bi050149T |
0.749 |
|
| 2005 |
Markowitz J, Rustandi RR, Varney KM, Wilder PT, Udan R, Wu SL, Horrocks WD, Weber DJ. Calcium-binding properties of wild-type and EF-hand mutants of S100B in the presence and absence of a peptide derived from the C-terminal negative regulatory domain of p53. Biochemistry. 44: 7305-14. PMID 15882069 DOI: 10.1021/Bi050321T |
0.835 |
|
| 2005 |
Wilder PT, Varney KM, Weiss MB, Gitti RK, Weber DJ. Solution structure of zinc- and calcium-bound rat S100B as determined by nuclear magnetic resonance spectroscopy. Biochemistry. 44: 5690-702. PMID 15823027 DOI: 10.1021/Bi0475830 |
0.839 |
|
| 2005 |
Weber DJ. Editorial Current Topics in Medicinal Chemistry. 5: 1091-1092. DOI: 10.2174/156802605774370919 |
0.293 |
|
| 2004 |
Markowitz J, Chen I, Gitti R, Baldisseri DM, Pan Y, Udan R, Carrier F, MacKerell AD, Weber DJ. Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction. Journal of Medicinal Chemistry. 47: 5085-93. PMID 15456252 DOI: 10.1021/Jm0497038 |
0.542 |
|
| 2004 |
Lin J, Yang Q, Yan Z, Markowitz J, Wilder PT, Carrier F, Weber DJ. Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells. The Journal of Biological Chemistry. 279: 34071-7. PMID 15178678 DOI: 10.1074/Jbc.M405419200 |
0.729 |
|
| 2004 |
Weber D, Markowitz J, MacKerell A, Carrier F. 72 Restoration of wild-type p53 in malignant melanoma European Journal of Cancer Supplements. 2: 25. DOI: 10.1016/S1359-6349(04)80080-6 |
0.252 |
|
| 2003 |
Wilder PT, Baldisseri DM, Udan R, Vallely KM, Weber DJ. Location of the Zn(2+)-binding site on S100B as determined by NMR spectroscopy and site-directed mutagenesis. Biochemistry. 42: 13410-21. PMID 14621986 DOI: 10.1021/Bi035334Q |
0.749 |
|
| 2003 |
Zimmer DB, Wright Sadosky P, Weber DJ. Molecular mechanisms of S100-target protein interactions Microscopy Research and Technique. 60: 552-559. PMID 12645003 DOI: 10.1002/Jemt.10297 |
0.536 |
|
| 2003 |
Wilder P, Baldisseri D, Udan R, Vallely K, Weber D. 1H, 13C, and 15N resonance assignments for Zn2+ and Ca2+ bound S100B Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5895 |
0.681 |
|
| 2002 |
Inman KG, Yang R, Rustandi RR, Miller KE, Baldisseri DM, Weber DJ. Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12. Journal of Molecular Biology. 324: 1003-14. PMID 12470955 DOI: 10.1016/S0022-2836(02)01152-X |
0.814 |
|
| 2002 |
Vallely KM, Rustandi RR, Ellis KC, Varlamova O, Bresnick AR, Weber DJ. Solution structure of human Mts1 (S100A4) as determined by NMR spectroscopy. Biochemistry. 41: 12670-80. PMID 12379109 DOI: 10.1021/Bi020365R |
0.825 |
|
| 2002 |
Baldisseri DM, Margolis JW, Weber DJ, Koo JH, Margolis FL. Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction. Journal of Molecular Biology. 319: 823-37. PMID 12054873 DOI: 10.1016/S0022-2836(02)00282-6 |
0.375 |
|
| 2002 |
Rustandi RR, Baldisseri DM, Inman KG, Nizner P, Hamilton SM, Landar A, Landar A, Zimmer DB, Weber DJ. Three-dimensional solution structure of the calcium-signaling protein apo-S100A1 as determined by NMR. Biochemistry. 41: 788-96. PMID 11790100 DOI: 10.1021/Bi0118308 |
0.835 |
|
| 2001 |
Lin J, Blake M, Tang C, Zimmer D, Rustandi RR, Weber DJ, Carrier F. Inhibition of p53 Transcriptional Activity by the S100B Calcium-binding Protein Journal of Biological Chemistry. 276: 35037-35041. PMID 11454863 DOI: 10.1074/Jbc.M104379200 |
0.727 |
|
| 2001 |
Rustandi R, Vallely KM, Varlamova O, Klein MG, Almo SC, Bresnick AR, Weber DJ. Letter to the editor: 1H, 13C, 15N NMR sequence-specific resonance assignments for human apo-Mts1 (S100A4) [3] Journal of Biomolecular Nmr. 19: 381-382. PMID 11370787 DOI: 10.1023/A:1011295415649 |
0.639 |
|
| 2001 |
Ellis KC, Tenenholz TC, Jerng H, Hayhurst M, Dudlak CS, Gilly WF, Blaustein MP, Weber DJ. Interaction of a toxin from the scorpion Tityus serrulatus with a cloned K+ channel from squid (sqKv1A). Biochemistry. 40: 5942-53. PMID 11352729 DOI: 10.1021/Bi010173G |
0.765 |
|
| 2001 |
Inman KG, Baldisseri DM, Miller KE, Weber DJ. Backbone dynamics of the calcium-signaling protein apo-S100B as determined by 15N NMR relaxation. Biochemistry. 40: 3439-48. PMID 11297409 DOI: 10.1021/Bi0027478 |
0.786 |
|
| 2001 |
Rustandi R, Vallely K, Varlamova O, Klein M, Almo S, Bresnick A, Weber D. 1H, 13C, and 15N Chemical Shift Assignments for apo-Mts1 (S100A4) Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4892 |
0.63 |
|
| 2000 |
Andrec M, Inman KG, Weber DJ, Levy RM, Montelione GT. A Bayesian statistical method for the detection and quantification of rotational diffusion anisotropy from NMR relaxation data. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 146: 66-80. PMID 10968959 DOI: 10.1006/Jmre.2000.2113 |
0.734 |
|
| 2000 |
Rustandi RR, Baldisseri DM, Weber DJ. Structure of the negative regulatory domain of p53 bound to S100B(ββ) Nature Structural Biology. 7: 570-574. PMID 10876243 DOI: 10.1038/76797 |
0.734 |
|
| 2000 |
Tenenholz TC, Klenk KC, Matteson DR, Blaustein MP, Weber DJ. Structural determinants of scorpion toxin affinity: the charybdotoxin (alpha-KTX) family of K(+)-channel blocking peptides. Reviews of Physiology, Biochemistry and Pharmacology. 140: 135-85. PMID 10857399 DOI: 10.1007/Bfb0035552 |
0.377 |
|
| 2000 |
Klenk KC, Tenenholz TC, Matteson DR, Rogowski RS, Blaustein MP, Weber DJ. Structural and functional differences of two toxins from the scorpion Pandinus imperator. Proteins. 38: 441-9. PMID 10707030 DOI: 10.1002/(Sici)1097-0134(20000301)38:4<441::Aid-Prot9>3.0.Co;2-L |
0.768 |
|
| 1999 |
Rustandi RR, Baldisseri DM, Drohat AC, Weber DJ. Structural changes in the C-terminus of Ca2+-bound rat S100B(ββ) upon binding to a peptide derived from the C-terminal regulatory domain of p53 Protein Science. 8: 1743-1751. PMID 10493575 DOI: 10.1110/Ps.8.9.1743 |
0.792 |
|
| 1999 |
Baldisseri DM, Rustandi RR, Zhang Z, Tang C, Bair CL, Landar A, Zimmer DB, Weber DJ. 1H, 13C, and 15N NMR sequence-specific resonance assignments for rat apo-S100A1(αα) [2] Journal of Biomolecular Nmr. 14: 91-92. PMID 10382312 DOI: 10.1023/A:1008301518346 |
0.599 |
|
| 1999 |
Mildvan AS, Weber DJ, Abeygunawardana C. Solution structure and mechanism of the MutT pyrophosphohydrolase. Advances in Enzymology and Related Areas of Molecular Biology. 73: 183-207. PMID 10218109 DOI: 10.1002/9780470123195.Ch6 |
0.606 |
|
| 1999 |
Drohat AC, Tjandra N, Baldisseri DM, Weber DJ. The use of dipolar couplings for determining the solution structure of rat apo-S100B (ββ) Protein Science. 8: 800-809. PMID 10211826 DOI: 10.1110/Ps.8.4.800 |
0.741 |
|
| 1999 |
Garbuglia M, Verzini M, Rustandi RR, Osterloh D, Weber DJ, Gerke V, Donato R. Role of the C-terminal extension in the interaction of S100A1 with GFAP, tubulin, the S100A1- and S100B-inhibitory peptide, TRTK-12, and a peptide derived from p53, and the S100A1 inhibitory effect on GFAP polymerization Biochemical and Biophysical Research Communications. 254: 36-41. PMID 9920729 DOI: 10.1006/Bbrc.1998.9881 |
0.68 |
|
| 1999 |
Baldisseri D, Rustandi R, Zhong Z, Tang C, Bair C, Landar A, Landar A, Zimmer D, Weber D. 1H, 13C and 15N NMR Sequence-Specific Resonance Assignments for Rat Apo-S100A1(aa). Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4285 |
0.631 |
|
| 1999 |
Drohat A, Baldisseri D, Rustandi R, Weber D. 1H, 13C, and 15N Resonance Assignments for Reduced Calcium-Bound S100B from Rat Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4105 |
0.76 |
|
| 1998 |
Wilder PT, Rustandi RR, Drohat AC, Weber DJ. S100B(betabeta) inhibits the protein kinase C-dependent phosphorylation of a peptide derived from p53 in a Ca2+-dependent manner. Protein Science : a Publication of the Protein Society. 7: 794-8. PMID 9541413 DOI: 10.1002/Pro.5560070330 |
0.824 |
|
| 1998 |
Drohat AC, Baldisseri DM, Rustandi RR, Weber DJ. Solution structure of calcium-bound rat S100B(ββ) as determined by nuclear magnetic resonance spectroscopy Biochemistry. 37: 2729-2740. PMID 9485423 DOI: 10.1021/Bi972635P |
0.816 |
|
| 1998 |
Rustandi RR, Drohat AC, Baldisseri DM, Wilder PT, Weber DJ. The Ca(2+)-dependent interaction of S100B(beta beta) with a peptide derived from p53. Biochemistry. 37: 1951-60. PMID 9485322 DOI: 10.1021/Bi972701N |
0.802 |
|
| 1998 |
Inman KG, Baldisseri PM, Weber DJ. Backbone dynamics of the calcium-binding protein apo-sloob(/5/3) from rat brain as determined by 'h-15n heteronuclear nmr relaxation Faseb Journal. 12: A1434. |
0.756 |
|
| 1998 |
Rustandi RR, Baldisseri DM, Probat AC, Weber DJ. Secondary structure of sloob(ββ) in s100b(ββ)-Ca+2-p53 peptide complex determined by NMR Faseb Journal. 12: A1415. |
0.384 |
|
| 1998 |
Drohat AG, Tjandra N, Baldisseri DM, Weber DJ. Refinement of the solution structure of rat Apo-S100B(ββ) using internuclear magnetic dipolar couplings measured by NMR in a dilute liquid crystalline medium Faseb Journal. 12: A1448. |
0.24 |
|
| 1998 |
Klenk K, Tenenholz T, Ogowski RSJR, Blaustein M, Weber DJ. Sequence specific assignment and secondary structure of a toxin for tityus serrulatus (TsTX-Ko) determined by NMR spectroscopy Faseb Journal. 12: A1448. |
0.286 |
|
| 1997 |
Landar A, Hall TL, Cornwall EH, Correia JJ, Drohat AC, Weber DJ, Zimmer DB. The role of cysteine residues in S100B dimerization and regulation of target protein activity Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1343: 117-129. PMID 9428666 DOI: 10.1016/S0167-4838(97)00126-X |
0.734 |
|
| 1997 |
Chaudhuri D, Horrocks WD, Amburgey JC, Weber DJ. Characterization of lanthanide ion binding to the EF-hand protein S100 beta by luminescence spectroscopy. Biochemistry. 36: 9674-80. PMID 9245399 DOI: 10.1021/Bi9704358 |
0.814 |
|
| 1997 |
Drohat AC, Nenortas E, Beckett D, Weber DJ. Oligomerization state of S100B at nanomolar concentration determined by large-zone analytical gel filtration chromatography. Protein Science : a Publication of the Protein Society. 6: 1577-82. PMID 9232658 DOI: 10.1002/Pro.5560060721 |
0.702 |
|
| 1997 |
Tenenholz TC, Rogowski RS, Collins JH, Blaustein MP, Weber DJ. Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels. Biochemistry. 36: 2763-71. PMID 9062103 DOI: 10.1021/bi9628432 |
0.257 |
|
| 1996 |
Rogowski RS, Collins JH, O'Neill TJ, Gustafson TA, Werkman TR, Rogawski MA, Tenenholz TC, Weber DJ, Blaustein MP. Three new toxins from the scorpion Pandinus imperator selectively block certain voltage-gated K+ channels. Molecular Pharmacology. 50: 1167-77. PMID 8913348 |
0.283 |
|
| 1996 |
Drohat AC, Amburgey JC, Abildgaard F, Starich MR, Baldisseri D, Weber DJ. Solution structure of rat Apo-S100B(ββ) as determined by NMR spectroscopy Biochemistry. 35: 11577-11588. PMID 8794737 DOI: 10.1021/Bi9612226 |
0.809 |
|
| 1995 |
Amburgey JC, Abildgaard F, Starich MR, Shah S, Hilt DC, Weber DJ. 1H, 13C and 15N NMR assignments and solution secondary structure of rat Apo-S100β Journal of Biomolecular Nmr. 6: 171-179. PMID 8589606 DOI: 10.1007/Bf00211781 |
0.795 |
|
| 1995 |
Frick DN, Weber DJ, Abeygunawardana C, Gittis AG, Bessman MJ, Mildvan AS. NMR studies of the conformations and location of nucleotides bound to the Escherichia coli MutT enzyme. Biochemistry. 34: 5577-86. PMID 7727419 DOI: 10.1021/Bi00016A032 |
0.611 |
|
| 1995 |
Abeygunawardana C, Weber DJ, Gittis AG, Frick DN, Lin J, Miller AF, Bessman MJ, Mildvan AS. Solution structure of the MutT enzyme, a nucleoside triphosphate pyrophosphohydrolase. Biochemistry. 34: 14997-5005. PMID 7578113 DOI: 10.1021/Bi00046A006 |
0.611 |
|
| 1994 |
Frick DN, Weber DJ, Gillespie JR, Bessman MJ, Mildvan AS. Dual divalent cation requirement of the MutT dGTPase. Kinetic and magnetic resonance studies of the metal and substrate complexes. The Journal of Biological Chemistry. 269: 1794-803. PMID 8294428 |
0.57 |
|
| 1994 |
Weber DJ, Libson AM, Gittis AG, Lebowitz MS, Mildvan AS. NMR docking of a substrate into the X-ray structure of the Asp-21-->Glu mutant of staphylococcal nuclease. Biochemistry. 33: 8017-28. PMID 8025106 DOI: 10.1021/Bi00192A005 |
0.615 |
|
| 1993 |
Weber DJ, Abeygunawardana C, Bessman MJ, Mildvan AS. Secondary structure of the MutT enzyme as determined by NMR. Biochemistry. 32: 13081-8. PMID 8241162 DOI: 10.1021/Bi00211A018 |
0.59 |
|
| 1993 |
Abeygunawardana C, Weber DJ, Frick DN, Bessman MJ, Mildvan AS. Sequence-specific assignments of the backbone 1H, 13C, and 15N resonances of the MutT enzyme by heteronuclear multidimensional NMR. Biochemistry. 32: 13071-80. PMID 8241161 DOI: 10.1021/Bi00211A017 |
0.593 |
|
| 1993 |
Chuang WJ, Weber DJ, Gittis AG, Mildvan AS. Mutational tests of the NMR-docked structure of the staphylococcal nuclease-metal-3',5'-pdTp complex. Proteins. 17: 36-48. PMID 8234243 DOI: 10.1002/Prot.340170107 |
0.652 |
|
| 1993 |
Weber DJ, Serpersu EH, Gittis AG, Lattman EE, Mildvan AS. NMR docking of the competitive inhibitor thymidine 3',5'-diphosphate into the X-ray structure of staphylococcal nuclease. Proteins. 17: 20-35. PMID 8234242 DOI: 10.1002/Prot.340170106 |
0.614 |
|
| 1992 |
Mildvan AS, Weber DJ, Kuliopulos A. Quantitative interpretations of double mutations of enzymes. Archives of Biochemistry and Biophysics. 294: 327-40. PMID 1567189 DOI: 10.1016/0003-9861(92)90692-P |
0.573 |
|
| 1992 |
Weber DJ, Berkowitz P, Panek MG, Huh NW, Pedersen LG, Hiskey RG. Modifications of bovine prothrombin fragment 1 in the presence and absence of Ca(II) ions. Loss of positive cooperativity in Ca(II) ion binding for the modified proteins. The Journal of Biological Chemistry. 267: 4564-9. PMID 1531656 |
0.643 |
|
| 1992 |
Weber DJ, Gittis AG, Mullen GP, Abeygunawardana C, Lattman EE, Mildvan AS. NMR docking of a substrate into the X-ray structure of staphylococcal nuclease. Proteins. 13: 275-87. PMID 1518799 DOI: 10.1002/Prot.340130402 |
0.623 |
|
| 1992 |
Weber DJ, Bhatnagar SK, Bullions LC, Bessman MJ, Mildvan AS. NMR and isotopic exchange studies of the site of bond cleavage in the MutT reaction. The Journal of Biological Chemistry. 267: 16939-42. PMID 1324915 |
0.542 |
|
| 1992 |
Berkowitz P, Huh NW, Brostrom KE, Panek MG, Weber DJ, Tulinsky A, Pedersen LG, Hiskey RG. A metal ion-binding site in the kringle region of bovine prothrombin fragment 1. The Journal of Biological Chemistry. 267: 4570-6. PMID 1311313 |
0.642 |
|
| 1991 |
Weber DJ, Mullen GP, Mildvan AS. Conformation of an enzyme-bound substrate of staphylococcal nuclease as determined by NMR. Biochemistry. 30: 7425-37. PMID 1854746 DOI: 10.1021/Bi00244A009 |
0.603 |
|
| 1991 |
Weber DJ, Meeker AK, Mildvan AS. Interactions of the acid and base catalysts on staphylococcal nuclease as studied in a double mutant. Biochemistry. 30: 6103-14. PMID 1676297 DOI: 10.1021/Bi00239A004 |
0.622 |
|
| 1990 |
Weber DJ, Serpersu EH, Shortle D, Mildvan AS. Diverse interactions between the individual mutations in a double mutant at the active site of staphylococcal nuclease. Biochemistry. 29: 8632-42. PMID 1702994 DOI: 10.1021/Bi00489A020 |
0.613 |
|
| 1988 |
Weber DJ, Pollock JS, Pedersen LG, Hiskey RG. The determination of a calcium-dependent binding constant of the bovine prothrombin Gla domain (residues 1-45) to phospholipid vesicles. Biochemical and Biophysical Research Communications. 155: 230-5. PMID 3415682 DOI: 10.1016/S0006-291X(88)81073-8 |
0.605 |
|
| 1988 |
Pollock JS, Shepard AJ, Weber DJ, Olson DL, Klapper DG, Pedersen LG, Hiskey RG. Phospholipid binding properties of bovine prothrombin peptide residues 1-45. The Journal of Biological Chemistry. 263: 14216-23. PMID 3170544 |
0.621 |
|
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