Joshua D. Rabinowitz - Publications

Affiliations: 
Chemistry and Integrative Genomics Princeton University, Princeton, NJ 
Area:
cellular metabolism
Website:
http://www.princeton.edu/genomics/rabinowitz/index.xml

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bradley PH, Gibney PA, Botstein D, Troyanskaya OG, Rabinowitz JD. Minor Isozymes Tailor Yeast Metabolism to Carbon Availability. Msystems. 4. PMID 30834327 DOI: 10.1128/mSystems.00170-18  1
2019 Rodriguez AE, Ducker GS, Billingham LK, Martinez CA, Mainolfi N, Suri V, Friedman A, Manfredi MG, Weinberg SE, Rabinowitz JD, Chandel NS. Serine Metabolism Supports Macrophage IL-1β Production. Cell Metabolism. PMID 30773464 DOI: 10.1016/j.cmet.2019.01.014  1
2018 Wang L, Xing X, Chen L, Yang L, Su X, Rabitz HA, Lu W, Rabinowitz JD. Peak annotation and verification engine (PAVE) for untargeted LC-MS metabolomics. Analytical Chemistry. PMID 30586294 DOI: 10.1021/acs.analchem.8b03132  0.44
2018 Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, ... Rabinowitz JD, et al. Author Correction: Autophagy maintains tumour growth through circulating arginine. Nature. PMID 30523330 DOI: 10.1038/s41586-018-0815-6  0.44
2018 Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, ... Rabinowitz JD, et al. Autophagy maintains tumour growth through circulating arginine. Nature. PMID 30429607 DOI: 10.1038/s41586-018-0697-7  0.44
2018 Xu YF, Lu W, Chen JC, Johnson SA, Gibney PA, Thomas DG, Brown G, May AL, Campagna SR, Yakunin AF, Botstein D, Rabinowitz JD. Discovery and functional characterization of a yeast sugar alcohol phosphatase. Acs Chemical Biology. PMID 30240188 DOI: 10.1021/acschembio.8b00804  0.76
2018 Li SH, Li Z, Park JO, King CG, Rabinowitz JD, Wingreen NS, Gitai Z. Escherichia coli translation strategies differ across carbon, nitrogen and phosphorus limitation conditions. Nature Microbiology. PMID 30038306 DOI: 10.1038/s41564-018-0199-2  0.32
2018 Rodan LH, Qi W, Ducker GS, Demirbas D, Laine R, Yang E, Walker MA, Eichler F, Rabinowitz JD, Anselm I, Berry GT. 5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. Molecular Genetics and Metabolism. PMID 30031689 DOI: 10.1016/j.ymgme.2018.06.006  1
2018 Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ. Publisher Correction: Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nature Medicine. PMID 29895835 DOI: 10.1038/s41591-018-0047-1  0.44
2018 Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ. Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nature Medicine. PMID 29578539 DOI: 10.1038/nm.4514  0.44
2018 Gibney PA, Schieler A, Chen JC, Bacha-Hummel JM, Botstein M, Volpe M, Silverman SJ, Xu Y, Bennett BD, Rabinowitz JD, Botstein D. Common and Divergent Features of Galactose-1-phosphate and Fructose-1-phosphate Toxicity in Yeast. Molecular Biology of the Cell. PMID 29444955 DOI: 10.1091/mbc.E17-11-0666  0.76
2018 Jang C, Hui S, Lu W, Cowan AJ, Morscher RJ, Lee G, Liu W, Tesz GJ, Birnbaum MJ, Rabinowitz JD. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metabolism. 27: 351-361.e3. PMID 29414685 DOI: 10.1016/j.cmet.2017.12.016  0.44
2018 Morscher RJ, Ducker GS, Li SH, Mayer JA, Gitai Z, Sperl W, Rabinowitz JD. Mitochondrial translation requires folate-dependent tRNA methylation. Nature. PMID 29364879 DOI: 10.1038/nature25460  1
2017 Ducker GS, Ghergurovich JM, Mainolfi N, Suri V, Jeong SK, Hsin-Jung Li S, Friedman A, Manfredi MG, Gitai Z, Kim H, Rabinowitz JD. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 114: 11404-11409. PMID 29073064 DOI: 10.1073/pnas.1706617114  1
2017 Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Le Zhan, Yanxiang Guo J, White E, Rabinowitz JD. Glucose feeds the TCA cycle via circulating lactate. Nature. PMID 29045397 DOI: 10.1038/nature24057  0.44
2017 Kim HI, Raffler J, Lu W, Lee JJ, Abbey D, Saleheen D, Rabinowitz JD, Bennett MJ, Hand NJ, Brown C, Rader DJ. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. American Journal of Human Genetics. PMID 28942964 DOI: 10.1016/j.ajhg.2017.08.008  0.44
2017 Liu L, Rowe GC, Yang S, Li J, Damilano F, Chan MC, Lu W, Jang C, Wada S, Morley M, Hesse M, Fleischmann BK, Rabinowitz J, Das S, Rosenzweig A, et al. PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy. Circulation Research. PMID 28928113 DOI: 10.1161/CIRCRESAHA.117.311456  0.44
2017 Oslund RC, Su X, Haugbro M, Kee JM, Esposito M, David Y, Wang B, Ge E, Perlman DH, Kang Y, Muir TW, Rabinowitz JD. Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate. Nature Chemical Biology. PMID 28805803 DOI: 10.1038/nchembio.2453  0.32
2017 Chen L, Ducker GS, Lu W, Teng X, Rabinowitz JD. An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate. Analytical and Bioanalytical Chemistry. PMID 28799108 DOI: 10.1007/s00216-017-0514-4  1
2017 Lu W, Su X, Klein MS, Lewis IA, Fiehn O, Rabinowitz JD. Metabolite Measurement: Pitfalls to Avoid and Practices to Follow. Annual Review of Biochemistry. 86: 277-304. PMID 28654323 DOI: 10.1146/annurev-biochem-061516-044952  0.44
2017 Gong Y, Cao R, Ding G, Hong S, Zhou W, Lu W, Damle M, Fang B, Wang CC, Qian J, Lie N, Lanzillotta C, Rabinowitz JD, Sun Z. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Molecular and Cellular Endocrinology. PMID 28554803 DOI: 10.1016/j.mce.2017.05.024  0.44
2017 Choi J, Rajagopal A, Xu YF, Rabinowitz JD, O'Shea EK. A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae. Plos One. 12: e0176085. PMID 28520786 DOI: 10.1371/journal.pone.0176085  0.32
2017 Lu W, Wang L, Chen L, Hui S, Rabinowitz JD. Extraction and quantitation of NAD(P)(H). Antioxidants & Redox Signaling. PMID 28497978 DOI: 10.1089/ars.2017.7014  0.44
2017 Su X, Lu W, Rabinowitz JD. Metabolite Spectral Accuracy on Orbitraps. Analytical Chemistry. PMID 28471646 DOI: 10.1021/acs.analchem.7b00396  0.44
2016 Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill BD, Molina H, Khurana TS, ... Rabinowitz JD, et al. Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nature Medicine. PMID 27991918 DOI: 10.1038/nm.4245  0.44
2016 Papazyan R, Sun Z, Kim YH, Titchenell PM, Hill DA, Lu W, Damle M, Wan M, Zhang Y, Briggs ER, Rabinowitz JD, Lazar MA. Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. Cell Metabolism. PMID 27866836 DOI: 10.1016/j.cmet.2016.10.012  0.44
2016 Hackett SR, Zanotelli VR, Xu W, Goya J, Park JO, Perlman DH, Gibney PA, Botstein D, Storey JD, Rabinowitz JD. Systems-level analysis of mechanisms regulating yeast metabolic flux. Science (New York, N.Y.). 354. PMID 27789812 DOI: 10.1126/science.aaf2786  0.76
2016 Ducker GS, Chen L, Morscher RJ, Ghergurovich JM, Esposito M, Teng X, Kang Y, Rabinowitz JD. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metabolism. 24: 640-641. PMID 27732838 DOI: 10.1016/j.cmet.2016.09.011  1
2016 Ducker GS, Rabinowitz JD. One-Carbon Metabolism in Health and Disease. Cell Metabolism. PMID 27641100 DOI: 10.1016/j.cmet.2016.08.009  1
2016 Koivunen P, Fell SM, Lu W, Rabinowitz JD, Kung AL, Schlisio S. The 2-oxoglutarate analog 3-oxoglutarate decreases normoxic hypoxia-inducible factor-1α in cancer cells, induces cell death, and reduces tumor xenograft growth. Hypoxia (Auckland, N.Z.). 4: 15-27. PMID 27525289 DOI: 10.2147/HP.S96366  0.44
2016 Guo JY, Teng X, Laddha SV, Ma S, Van Nostrand SC, Yang Y, Khor S, Chan CS, Rabinowitz JD, White E. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells. Genes & Development. PMID 27516533 DOI: 10.1101/gad.283416.116  1
2016 Titchenell PM, Quinn WJ, Lu M, Chu Q, Lu W, Li C, Chen H, Monks BR, Chen J, Rabinowitz JD, Birnbaum MJ. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. Cell Metabolism. PMID 27238637 DOI: 10.1016/j.cmet.2016.04.022  0.44
2016 Ducker GS, Chen L, Morscher RJ, Ghergurovich JM, Esposito M, Teng X, Kang Y, Rabinowitz JD. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metabolism. PMID 27211901 DOI: 10.1016/j.cmet.2016.04.016  1
2016 Park JO, Rubin SA, Xu YF, Amador-Noguez D, Fan J, Shlomi T, Rabinowitz JD. Metabolite concentrations, fluxes and free energies imply efficient enzyme usage. Nature Chemical Biology. PMID 27159581 DOI: 10.1038/nchembio.2077  1
2016 Bren A, Park JO, Towbin BD, Dekel E, Rabinowitz JD, Alon U. Glucose becomes one of the worst carbon sources for E.coli on poor nitrogen sources due to suboptimal levels of cAMP. Scientific Reports. 6: 24834. PMID 27109914 DOI: 10.1038/srep24834  1
2016 Rabinowitz JD, Coller HA. Partners in the Warburg effect. Elife. 5. PMID 27073176 DOI: 10.7554/eLife.15938  1
2016 Liu L, Shah S, Fan J, Park JO, Wellen KE, Rabinowitz JD. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nature Chemical Biology. PMID 26999781 DOI: 10.1038/nchembio.2047  1
2015 Su X, Wellen KE, Rabinowitz JD. Metabolic control of methylation and acetylation. Current Opinion in Chemical Biology. 30: 52-60. PMID 26629854 DOI: 10.1016/j.cbpa.2015.10.030  1
2015 Mok WW, Park JO, Rabinowitz JD, Brynildsen MP. RNA Futile Cycling in Model Persisters Derived from MazF Accumulation. Mbio. 6. PMID 26578677 DOI: 10.1128/mBio.01588-15  1
2015 Gibney PA, Schieler A, Chen JC, Rabinowitz JD, Botstein D. Characterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporter. Proceedings of the National Academy of Sciences of the United States of America. 112: 6116-21. PMID 25918382 DOI: 10.1073/pnas.1506289112  1
2015 Purdy JG, Shenk T, Rabinowitz JD. Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication. Cell Reports. 10: 1375-85. PMID 25732827 DOI: 10.1016/j.celrep.2015.02.003  1
2015 Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, ... ... Rabinowitz JD, et al. A roadmap for interpreting (13)C metabolite labeling patterns from cells. Current Opinion in Biotechnology. 34: 189-201. PMID 25731751 DOI: 10.1016/j.copbio.2015.02.003  1
2015 Kamphorst JJ, Nofal M, Commisso C, Hackett SR, Lu W, Grabocka E, Vander Heiden MG, Miller G, Drebin JA, Bar-Sagi D, Thompson CB, Rabinowitz JD. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Research. 75: 544-53. PMID 25644265 DOI: 10.1158/0008-5472.CAN-14-2211  0.44
2015 Ducker GS, Rabinowitz JD. ZMP: a master regulator of one-carbon metabolism. Molecular Cell. 57: 203-4. PMID 25616065 DOI: 10.1016/j.molcel.2015.01.012  1
2015 Xu YF, Lu W, Rabinowitz JD. Avoiding misannotation of in-source fragmentation products as cellular metabolites in liquid chromatography-mass spectrometry-based metabolomics. Analytical Chemistry. 87: 2273-81. PMID 25591916 DOI: 10.1021/ac504118y  1
2015 Aristilde L, Lewis IA, Park JO, Rabinowitz JD. Hierarchy in pentose sugar metabolism in Clostridium acetobutylicum. Applied and Environmental Microbiology. 81: 1452-62. PMID 25527534 DOI: 10.1128/AEM.03199-14  1
2015 Fan J, Teng X, Liu L, Mattaini KR, Looper RE, Vander Heiden MG, Rabinowitz JD. Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate. Acs Chemical Biology. 10: 510-6. PMID 25406093 DOI: 10.1021/cb500683c  1
2014 Hwang J, Purdy JG, Wu K, Rabinowitz JD, Shenk T. Estrogen-related receptor α is required for efficient human cytomegalovirus replication. Proceedings of the National Academy of Sciences of the United States of America. 111: E5706-15. PMID 25512541 DOI: 10.1073/pnas.1422361112  1
2014 Castellana M, Wilson MZ, Xu Y, Joshi P, Cristea IM, Rabinowitz JD, Gitai Z, Wingreen NS. Enzyme clustering accelerates processing of intermediates through metabolic channeling. Nature Biotechnology. 32: 1011-8. PMID 25262299 DOI: 10.1038/nbt.3018  1
2014 Stincone A, Prigione A, Cramer T, Wamelink MM, Campbell K, Cheung E, Olin-Sandoval V, Grüning N, Krüger A, Tauqeer Alam M, Keller MA, Breitenbach M, Brindle KM, Rabinowitz JD, Ralser M. The return of metabolism: biochemistry and physiology of the pentose phosphate pathway. Biological Reviews of the Cambridge Philosophical Society. PMID 25243985 DOI: 10.1111/brv.12140  1
2014 Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Molecular Cell. 56: 205-18. PMID 25242145 DOI: 10.1016/j.molcel.2014.08.018  1
2014 Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB. Serine catabolism regulates mitochondrial redox control during hypoxia. Cancer Discovery. 4: 1406-17. PMID 25186948 DOI: 10.1158/2159-8290.CD-14-0250  1
2014 Mathew R, Khor S, Hackett SR, Rabinowitz JD, Perlman DH, White E. Functional role of autophagy-mediated proteome remodeling in cell survival signaling and innate immunity. Molecular Cell. 55: 916-30. PMID 25175026 DOI: 10.1016/j.molcel.2014.07.019  1
2014 Karsli-Uzunbas G, Guo JY, Price S, Teng X, Laddha SV, Khor S, Kalaany NY, Jacks T, Chan CS, Rabinowitz JD, White E. Autophagy is required for glucose homeostasis and lung tumor maintenance. Cancer Discovery. 4: 914-27. PMID 24875857 DOI: 10.1158/2159-8290.CD-14-0363  1
2014 Fan J, Ye J, Kamphorst JJ, Shlomi T, Thompson CB, Rabinowitz JD. Quantitative flux analysis reveals folate-dependent NADPH production. Nature. 510: 298-302. PMID 24805240 DOI: 10.1038/nature13236  1
2014 Breunig JS, Hackett SR, Rabinowitz JD, Kruglyak L. Genetic basis of metabolome variation in yeast. Plos Genetics. 10: e1004142. PMID 24603560 DOI: 10.1371/journal.pgen.1004142  1
2014 Shlomi T, Fan J, Tang B, Kruger WD, Rabinowitz JD. Quantitation of cellular metabolic fluxes of methionine. Analytical Chemistry. 86: 1583-91. PMID 24397525 DOI: 10.1021/ac4032093  1
2013 Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM. Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. Cell Reports. 5: 1725-36. PMID 24360963 DOI: 10.1016/j.celrep.2013.11.040  0.32
2013 Fan J, Kamphorst JJ, Mathew R, Chung MK, White E, Shlomi T, Rabinowitz JD. Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Molecular Systems Biology. 9: 712. PMID 24301801 DOI: 10.1038/msb.2013.65  1
2013 Grady SL, Purdy JG, Rabinowitz JD, Shenk T. Argininosuccinate synthetase 1 depletion produces a metabolic state conducive to herpes simplex virus 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 110: E5006-15. PMID 24297925 DOI: 10.1073/pnas.1321305110  1
2013 Tchigvintsev A, Tchigvintsev D, Flick R, Popovic A, Dong A, Xu X, Brown G, Lu W, Wu H, Cui H, Dombrowski L, Joo JC, Beloglazova N, Min J, Savchenko A, ... ... Rabinowitz JD, et al. Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides. Chemistry & Biology. 20: 1386-98. PMID 24210219 DOI: 10.1016/j.chembiol.2013.09.011  1
2013 Tepper N, Noor E, Amador-Noguez D, Haraldsdóttir HS, Milo R, Rabinowitz J, Liebermeister W, Shlomi T. Steady-State Metabolite Concentrations Reflect a Balance between Maximizing Enzyme Efficiency and Minimizing Total Metabolite Load Plos One. 8. PMID 24086517 DOI: 10.1371/journal.pone.0075370  1
2013 Fan J, Kamphorst JJ, Rabinowitz JD, Shlomi T. Fatty acid labeling from glutamine in hypoxia can be explained by isotope exchange without net reductive isocitrate dehydrogenase (IDH) flux. The Journal of Biological Chemistry. 288: 31363-9. PMID 24030823 DOI: 10.1074/jbc.M113.502740  1
2013 Rabinowitz JD, Silhavy TJ. Systems biology: metabolite turns master regulator. Nature. 500: 283-4. PMID 23925111 DOI: 10.1038/nature12544  1
2013 Reaves ML, Young BD, Hosios AM, Xu YF, Rabinowitz JD. Pyrimidine homeostasis is accomplished by directed overflow metabolism. Nature. 500: 237-41. PMID 23903661 DOI: 10.1038/nature12445  1
2013 Guo JY, Karsli-Uzunbas G, Mathew R, Aisner SC, Kamphorst JJ, Strohecker AM, Chen G, Price S, Lu W, Teng X, Snyder E, Santanam U, Dipaola RS, Jacks T, Rabinowitz JD, et al. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. Genes & Development. 27: 1447-61. PMID 23824538 DOI: 10.1101/gad.219642.113  1
2013 Koyuncu E, Purdy JG, Rabinowitz JD, Shenk T. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. Plos Pathogens. 9: e1003333. PMID 23696731 DOI: 10.1371/journal.ppat.1003333  1
2013 Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP, Thompson CB, Rabinowitz JD. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proceedings of the National Academy of Sciences of the United States of America. 110: 8882-7. PMID 23671091 DOI: 10.1073/pnas.1307237110  1
2013 Xu YF, Létisse F, Absalan F, Lu W, Kuznetsova E, Brown G, Caudy AA, Yakunin AF, Broach JR, Rabinowitz JD. Nucleotide degradation and ribose salvage in yeast. Molecular Systems Biology. 9: 665. PMID 23670538 DOI: 10.1038/msb.2013.21  1
2013 Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 497: 633-7. PMID 23665962 DOI: 10.1038/nature12138  1
2013 Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 497: 652. PMID 23615611 DOI: 10.1038/nature12164  1
2013 Shlomi T, Rabinowitz JD. Metabolism: Cancer mistunes methylation. Nature Chemical Biology. 9: 293-4. PMID 23594782 DOI: 10.1038/nchembio.1234  1
2012 Xu YF, Zhao X, Glass DS, Absalan F, Perlman DH, Broach JR, Rabinowitz JD. Regulation of yeast pyruvate kinase by ultrasensitive allostery independent of phosphorylation. Molecular Cell. 48: 52-62. PMID 22902555 DOI: 10.1016/j.molcel.2012.07.013  1
2012 Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen HY, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. Plos One. 7: e41831. PMID 22848625 DOI: 10.1371/journal.pone.0041831  1
2012 Reaves ML, Sinha S, Rabinowitz JD, Kruglyak L, Redfield RJ. Absence of detectable arsenate in DNA from arsenate-grown GFAJ-1 cells. Science (New York, N.Y.). 337: 470-3. PMID 22773140 DOI: 10.1126/science.1219861  1
2012 Grady SL, Hwang J, Vastag L, Rabinowitz JD, Shenk T. Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase. Journal of Virology. 86: 8259-68. PMID 22623791 DOI: 10.1128/JVI.00495-12  1
2012 Rabinowitz JD, Vastag L. Teaching the design principles of metabolism. Nature Chemical Biology. 8: 497-501. PMID 22596190 DOI: 10.1038/nchembio.969  1
2012 Xu YF, Amador-Noguez D, Reaves ML, Feng XJ, Rabinowitz JD. Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase. Nature Chemical Biology. 8: 562-8. PMID 22522319 DOI: 10.1038/nchembio.941  1
2012 Ye J, Mancuso A, Tong X, Ward PS, Fan J, Rabinowitz JD, Thompson CB. Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 109: 6904-9. PMID 22509023 DOI: 10.1073/pnas.1204176109  1
2012 Peterson CN, Levchenko I, Rabinowitz JD, Baker TA, Silhavy TJ. RpoS proteolysis is controlled directly by ATP levels in Escherichia coli. Genes & Development. 26: 548-53. PMID 22426532 DOI: 10.1101/gad.183517.111  1
2012 Clasquin MF, Melamud E, Rabinowitz JD. LC-MS data processing with MAVEN: a metabolomic analysis and visualization engine. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit14.11. PMID 22389014 DOI: 10.1002/0471250953.bi1411s37  1
2012 Terry LJ, Vastag L, Rabinowitz JD, Shenk T. Human kinome profiling identifies a requirement for AMP-activated protein kinase during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 3071-6. PMID 22315427 DOI: 10.1073/pnas.1200494109  1
2011 Rabinowitz JD, Purdy JG, Vastag L, Shenk T, Koyuncu E. Metabolomics in drug target discovery. Cold Spring Harbor Symposia On Quantitative Biology. 76: 235-46. PMID 22114327 DOI: 10.1101/sqb.2011.76.010694  1
2011 Kamphorst JJ, Fan J, Lu W, White E, Rabinowitz JD. Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism. Analytical Chemistry. 83: 9114-22. PMID 22004349 DOI: 10.1021/ac202220b  1
2011 Doucette CD, Schwab DJ, Wingreen NS, Rabinowitz JD. α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition. Nature Chemical Biology. 7: 894-901. PMID 22002719 DOI: 10.1038/nchembio.685  1
2011 Amador-Noguez D, Brasg IA, Feng XJ, Roquet N, Rabinowitz JD. Metabolome remodeling during the acidogenic-solventogenic transition in Clostridium acetobutylicum. Applied and Environmental Microbiology. 77: 7984-97. PMID 21948824 DOI: 10.1128/AEM.05374-11  1
2011 Strelko CL, Lu W, Dufort FJ, Seyfried TN, Chiles TC, Rabinowitz JD, Roberts MF. Itaconic acid is a mammalian metabolite induced during macrophage activation. Journal of the American Chemical Society. 133: 16386-9. PMID 21919507 DOI: 10.1021/ja2070889  1
2011 Vastag L, Koyuncu E, Grady SL, Shenk TE, Rabinowitz JD. Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism. Plos Pathogens. 7: e1002124. PMID 21779165 DOI: 10.1371/journal.ppat.1002124  1
2011 Liu ST, Sharon-Friling R, Ivanova P, Milne SB, Myers DS, Rabinowitz JD, Brown HA, Shenk T. Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress. Proceedings of the National Academy of Sciences of the United States of America. 108: 12869-74. PMID 21768361 DOI: 10.1073/pnas.1109796108  1
2011 Petti AA, Crutchfield CA, Rabinowitz JD, Botstein D. Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 108: E1089-98. PMID 21734149 DOI: 10.1073/pnas.1101494108  1
2011 Clasquin MF, Melamud E, Singer A, Gooding JR, Xu X, Dong A, Cui H, Campagna SR, Savchenko A, Yakunin AF, Rabinowitz JD, Caudy AA. Riboneogenesis in yeast. Cell. 145: 969-80. PMID 21663798 DOI: 10.1016/j.cell.2011.05.022  1
2011 Reaves ML, Rabinowitz JD. Characteristic phenotypes associated with ptsN-null mutants in Escherichia coli K-12 are absent in strains with functional ilvG. Journal of Bacteriology. 193: 4576-81. PMID 21531803 DOI: 10.1128/JB.00325-11  1
2011 Vastag L, Jorgensen P, Peshkin L, Wei R, Rabinowitz JD, Kirschner MW. Remodeling of the metabolome during early frog development. Plos One. 6: e16881. PMID 21347444 DOI: 10.1371/journal.pone.0016881  1
2011 Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, Kamphorst JJ, Chen G, Lemons JM, Karantza V, Coller HA, Dipaola RS, Gelinas C, Rabinowitz JD, White E. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes & Development. 25: 460-70. PMID 21317241 DOI: 10.1101/gad.2016311  1
2011 Klosinska MM, Crutchfield CA, Bradley PH, Rabinowitz JD, Broach JR. Yeast cells can access distinct quiescent states. Genes & Development. 25: 336-49. PMID 21289062 DOI: 10.1101/gad.2011311  1
2011 Hart Y, Madar D, Yuan J, Bren A, Mayo AE, Rabinowitz JD, Alon U. Robust control of nitrogen assimilation by a bifunctional enzyme in E. coli. Molecular Cell. 41: 117-27. PMID 21211727 DOI: 10.1016/j.molcel.2010.12.023  1
2011 Reaves ML, Rabinowitz JD. Metabolomics in systems microbiology. Current Opinion in Biotechnology. 22: 17-25. PMID 21050741 DOI: 10.1016/j.copbio.2010.10.001  1
2010 Rabinowitz JD, White E. Autophagy and metabolism. Science (New York, N.Y.). 330: 1344-8. PMID 21127245 DOI: 10.1126/science.1193497  1
2010 Wellen KE, Lu C, Mancuso A, Lemons JM, Ryczko M, Dennis JW, Rabinowitz JD, Coller HA, Thompson CB. The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. Genes & Development. 24: 2784-99. PMID 21106670 DOI: 10.1101/gad.1985910  1
2010 Melamud E, Vastag L, Rabinowitz JD. Metabolomic analysis and visualization engine for LC-MS data. Analytical Chemistry. 82: 9818-26. PMID 21049934 DOI: 10.1021/ac1021166  1
2010 Lemons JM, Feng XJ, Bennett BD, Legesse-Miller A, Johnson EL, Raitman I, Pollina EA, Rabitz HA, Rabinowitz JD, Coller HA. Quiescent fibroblasts exhibit high metabolic activity. Plos Biology. 8: e1000514. PMID 21049082 DOI: 10.1371/journal.pbio.1000514  1
2010 Seltzer MJ, Bennett BD, Joshi AD, Gao P, Thomas AG, Ferraris DV, Tsukamoto T, Rojas CJ, Slusher BS, Rabinowitz JD, Dang CV, Riggins GJ. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Research. 70: 8981-7. PMID 21045145 DOI: 10.1158/0008-5472.CAN-10-1666  1
2010 Merritt JH, Ha DG, Cowles KN, Lu W, Morales DK, Rabinowitz J, Gitai Z, O'Toole GA. Specific control of Pseudomonas aeruginosa surface-associated behaviors by two c-di-GMP diguanylate cyclases. Mbio. 1. PMID 20978535 DOI: 10.1128/mBio.00183-10  1
2010 Crutchfield CA, Lu W, Melamud E, Rabinowitz JD. Mass spectrometry-based metabolomics of yeast. Methods in Enzymology. 470: 393-426. PMID 20946819 DOI: 10.1016/S0076-6879(10)70016-1  1
2010 Vander Heiden MG, Locasale JW, Swanson KD, Sharfi H, Heffron GJ, Amador-Noguez D, Christofk HR, Wagner G, Rabinowitz JD, Asara JM, Cantley LC. Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science (New York, N.Y.). 329: 1492-9. PMID 20847263 DOI: 10.1126/science.1188015  1
2010 Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 466: 774-8. PMID 20686576 DOI: 10.1038/nature09301  1
2010 Amador-Noguez D, Feng XJ, Fan J, Roquet N, Rabitz H, Rabinowitz JD. Systems-level metabolic flux profiling elucidates a complete, bifurcated tricarboxylic acid cycle in Clostridium acetobutylicum. Journal of Bacteriology. 192: 4452-61. PMID 20622067 DOI: 10.1128/JB.00490-10  1
2010 Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, ... Rabinowitz JD, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 465: 966. PMID 20559394 DOI: 10.1038/nature09132  1
2010 Kwon YK, Higgins MB, Rabinowitz JD. Antifolate-induced depletion of intracellular glycine and purines inhibits thymineless death in E. coli. Acs Chemical Biology. 5: 787-95. PMID 20553049 DOI: 10.1021/cb100096f  1
2010 Goyal S, Yuan J, Chen T, Rabinowitz JD, Wingreen NS. Achieving optimal growth through product feedback inhibition in metabolism. Plos Computational Biology. 6: e1000802. PMID 20532205 DOI: 10.1371/journal.pcbi.1000802  1
2010 Goodarzi H, Bennett BD, Amini S, Reaves ML, Hottes AK, Rabinowitz JD, Tavazoie S. Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli. Molecular Systems Biology. 6: 378. PMID 20531407 DOI: 10.1038/msb.2010.33  1
2010 Lu W, Clasquin MF, Melamud E, Amador-Noguez D, Caudy AA, Rabinowitz JD. Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. Analytical Chemistry. 82: 3212-21. PMID 20349993 DOI: 10.1021/ac902837x  1
2010 Kuchma SL, Ballok AE, Merritt JH, Hammond JH, Lu W, Rabinowitz JD, O'Toole GA. Cyclic-di-GMP-mediated repression of swarming motility by Pseudomonas aeruginosa: the pilY1 gene and its impact on surface-associated behaviors. Journal of Bacteriology. 192: 2950-64. PMID 20233936 DOI: 10.1128/JB.01642-09  1
2010 Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell. 17: 225-34. PMID 20171147 DOI: 10.1016/j.ccr.2010.01.020  1
2010 Monds RD, Newell PD, Wagner JC, Schwartzman JA, Lu W, Rabinowitz JD, O'Toole GA. Di-adenosine tetraphosphate (Ap4A) metabolism impacts biofilm formation by Pseudomonas fluorescens via modulation of c-di-GMP-dependent pathways. Journal of Bacteriology. 192: 3011-23. PMID 20154123 DOI: 10.1128/JB.01571-09  1
2010 Lu X, Bennet B, Mu E, Rabinowitz J, Kang Y. Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor model Journal of Biological Chemistry. 285: 9317-9321. PMID 20139083 DOI: 10.1074/jbc.C110.104448  1
2010 Boer VM, Crutchfield CA, Bradley PH, Botstein D, Rabinowitz JD. Growth-limiting intracellular metabolites in yeast growing under diverse nutrient limitations. Molecular Biology of the Cell. 21: 198-211. PMID 19889834 DOI: 10.1091/mbc.E09-07-0597  1
2010 Dimaggio PA, McAllister SR, Floudas CA, Feng XJ, Rabinowitz JD, Rabitz HA. A network flow model for biclustering via optimal re-ordering of data matrices Journal of Global Optimization. 47: 343-354. DOI: 10.1007/s10898-008-9349-z  1
2010 DiMaggio PA, McAllister SR, Floudas CA, Feng XJ, Li G, Rabinowitz JD, Rabitz HA. Enhancing molecular discovery using descriptor-free rearrangement clustering techniques for sparse data sets Aiche Journal. 56: 405-418. DOI: 10.1002/aic.11986  1
2009 Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, ... Rabinowitz JD, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 462: 739-44. PMID 19935646 DOI: 10.1038/nature08617  1
2009 Kelly RC, Bolitho ME, Higgins DA, Lu W, Ng WL, Jeffrey PD, Rabinowitz JD, Semmelhack MF, Hughson FM, Bassler BL. The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA. Nature Chemical Biology. 5: 891-5. PMID 19838203 DOI: 10.1038/nchembio.237  1
2009 Yuan J, Doucette CD, Fowler WU, Feng XJ, Piazza M, Rabitz HA, Wingreen NS, Rabinowitz JD. Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli. Molecular Systems Biology. 5: 302. PMID 19690571 DOI: 10.1038/msb.2009.60  1
2009 Bennett BD, Kimball EH, Gao M, Osterhout R, Van Dien SJ, Rabinowitz JD. Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. Nature Chemical Biology. 5: 593-9. PMID 19561621 DOI: 10.1038/nchembio.186  1
2009 Shinar G, Rabinowitz JD, Alon U. Robustness in glyoxylate bypass regulation. Plos Computational Biology. 5: e1000297. PMID 19266029 DOI: 10.1371/journal.pcbi.1000297  1
2009 Olszewski KL, Morrisey JM, Wilinski D, Burns JM, Vaidya AB, Rabinowitz JD, Llinás M. Host-parasite interactions revealed by Plasmodium falciparum metabolomics. Cell Host & Microbe. 5: 191-9. PMID 19218089 DOI: 10.1016/j.chom.2009.01.004  1
2009 Bradley PH, Brauer MJ, Rabinowitz JD, Troyanskaya OG. Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae. Plos Computational Biology. 5: e1000270. PMID 19180179 DOI: 10.1371/journal.pcbi.1000270  1
2008 DiMaggio PA, McAllister SR, Floudas CA, Feng XJ, Rabinowitz JD, Rabitz HA. Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies. Bmc Bioinformatics. 9: 458. PMID 18954459 DOI: 10.1186/1471-2105-9-458  1
2008 McAllister SR, Feng XJ, DiMaggio PA, Floudas CA, Rabinowitz JD, Rabitz H. Descriptor-free molecular discovery in large libraries by adaptive substituent reordering. Bioorganic & Medicinal Chemistry Letters. 18: 5967-70. PMID 18851908 DOI: 10.1016/j.bmcl.2008.09.068  1
2008 Munger J, Bennett BD, Parikh A, Feng XJ, McArdle J, Rabitz HA, Shenk T, Rabinowitz JD. Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy. Nature Biotechnology. 26: 1179-86. PMID 18820684 DOI: 10.1038/nbt.1500  1
2008 Kwon YK, Lu W, Melamud E, Khanam N, Bognar A, Rabinowitz JD. A domino effect in antifolate drug action in Escherichia coli. Nature Chemical Biology. 4: 602-8. PMID 18724364 DOI: 10.1038/nchembio.108  1
2008 Yuan J, Bennett BD, Rabinowitz JD. Kinetic flux profiling for quantitation of cellular metabolic fluxes. Nature Protocols. 3: 1328-40. PMID 18714301 DOI: 10.1038/nprot.2008.131  1
2008 Bennett BD, Yuan J, Kimball EH, Rabinowitz JD. Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach. Nature Protocols. 3: 1299-311. PMID 18714298 DOI: 10.1038/nprot.2008.107  1
2008 Lu W, Bennett BD, Rabinowitz JD. Analytical strategies for LC-MS-based targeted metabolomics. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 871: 236-42. PMID 18502704 DOI: 10.1016/j.jchromb.2008.04.031  1
2008 Rabinowitz JD, Hsiao JJ, Gryncel KR, Kantrowitz ER, Feng XJ, Li G, Rabitz H. Dissecting enzyme regulation by multiple allosteric effectors: nucleotide regulation of aspartate transcarbamoylase. Biochemistry. 47: 5881-8. PMID 18454556 DOI: 10.1021/bi8000566  1
2008 Piazza M, Feng XJ, Rabinowitz JD, Rabitz H. Diverse metabolic model parameters generate similar methionine cycle dynamics. Journal of Theoretical Biology. 251: 628-39. PMID 18313076 DOI: 10.1016/j.jtbi.2007.12.009  1
2008 Waters CM, Lu W, Rabinowitz JD, Bassler BL. Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT. Journal of Bacteriology. 190: 2527-36. PMID 18223081 DOI: 10.1128/JB.01756-07  1
2008 Feng X, Rabinowitz J, Rabitz H. Development of laboratory and computational techniques for optimal and quantitative understanding of cellular metabolic networks Ipdps Miami 2008 - Proceedings of the 22nd Ieee International Parallel and Distributed Processing Symposium, Program and Cd-Rom. DOI: 10.1109/IPDPS.2008.4536416  1
2008 DiMaggio PA, McAllister SR, Floudas CA, Feng XJ, Rabinowitz JD, Rabitz HA. Biclustering of data matrices in systems biology via optimal re-ordering Computer Aided Chemical Engineering. 25: 569-574. DOI: 10.1016/S1570-7946(08)80100-9  1
2008 Dimaggio PA, Mcallister SR, Floudas CA, Feng XJ, Rabinowitz JD, Rabitz HA. Optimal methods for re-ordering data matrices in systems biology and drug discovery applications Biophysical Reviews and Letters. 3: 19-42.  1
2007 Rabinowitz JD, Kimball E. Acidic acetonitrile for cellular metabolome extraction from Escherichia coli. Analytical Chemistry. 79: 6167-73. PMID 17630720 DOI: 10.1021/ac070470c  1
2007 Yuan J, Rabinowitz JD. Differentiating metabolites formed from de novo synthesis versus macromolecule decomposition. Journal of the American Chemical Society. 129: 9294-5. PMID 17616198 DOI: 10.1021/ja072997c  1
2007 Rabinowitz JD. Cellular metabolomics of Escherchia coli. Expert Review of Proteomics. 4: 187-98. PMID 17425455 DOI: 10.1586/14789450.4.2.187  1
2007 Lu W, Kwon YK, Rabinowitz JD. Isotope ratio-based profiling of microbial folates. Journal of the American Society For Mass Spectrometry. 18: 898-909. PMID 17360194 DOI: 10.1016/j.jasms.2007.01.017  1
2007 Bao Q, Lu W, Rabinowitz JD, Shi Y. Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1. Molecular Cell. 25: 181-92. PMID 17244527 DOI: 10.1016/j.molcel.2006.12.013  1
2007 Myers DJ, Timmons RD, Lu AT, Hale RL, Solas DW, Soni P, Rabinowitz JD. The effect of film thickness on thermal aerosol generation. Pharmaceutical Research. 24: 336-42. PMID 17180726 DOI: 10.1007/s11095-006-9153-8  1
2007 Avram MJ, Henthorn TK, Spyker DA, Krejcie TC, Lloyd PM, Cassella JV, Rabinowitz JD. Recirculatory pharmacokinetic model of the uptake, distribution, and bioavailability of prochlorperazine administered as a thermally generated aerosol in a single breath to dogs. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 262-7. PMID 17079359 DOI: 10.1124/dmd.106.010652  1
2006 Munger J, Bajad SU, Coller HA, Shenk T, Rabinowitz JD. Dynamics of the cellular metabolome during human cytomegalovirus infection. Plos Pathogens. 2: e132. PMID 17173481 DOI: 10.1371/journal.ppat.0020132  1
2006 Brauer MJ, Yuan J, Bennett BD, Lu W, Kimball E, Botstein D, Rabinowitz JD. Conservation of the metabolomic response to starvation across two divergent microbes. Proceedings of the National Academy of Sciences of the United States of America. 103: 19302-7. PMID 17159141 DOI: 10.1073/pnas.0609508103  1
2006 Hess DC, Lu W, Rabinowitz JD, Botstein D. Ammonium toxicity and potassium limitation in yeast. Plos Biology. 4: e351. PMID 17048990 DOI: 10.1371/journal.pbio.0040351  1
2006 Kimball E, Rabinowitz JD. Identifying decomposition products in extracts of cellular metabolites. Analytical Biochemistry. 358: 273-80. PMID 16962982 DOI: 10.1016/j.ab.2006.07.038  1
2006 Yuan J, Fowler WU, Kimball E, Lu W, Rabinowitz JD. Kinetic flux profiling of nitrogen assimilation in Escherichia coli. Nature Chemical Biology. 2: 529-30. PMID 16936719 DOI: 10.1038/nchembio816  1
2006 Rabinowitz JD, Lloyd PM, Munzar P, Myers DJ, Cross S, Damani R, Quintana R, Spyker DA, Soni P, Cassella JV. Ultra-fast absorption of amorphous pure drug aerosols via deep lung inhalation. Journal of Pharmaceutical Sciences. 95: 2438-51. PMID 16886198 DOI: 10.1002/jps.20694  1
2006 Bajad SU, Lu W, Kimball EH, Yuan J, Peterson C, Rabinowitz JD. Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry. Journal of Chromatography. A. 1125: 76-88. PMID 16759663 DOI: 10.1016/j.chroma.2006.05.019  1
2006 Lu W, Kimball E, Rabinowitz JD. A high-performance liquid chromatography-tandem mass spectrometry method for quantitation of nitrogen-containing intracellular metabolites. Journal of the American Society For Mass Spectrometry. 17: 37-50. PMID 16352439 DOI: 10.1016/j.jasms.2005.09.001  1
2004 Rabinowitz JD, Wensley M, Lloyd P, Myers D, Shen W, Lu A, Hodges C, Hale R, Mufson D, Zaffaroni A. Fast onset medications through thermally generated aerosols. The Journal of Pharmacology and Experimental Therapeutics. 309: 769-75. PMID 14752061 DOI: 10.1124/jpet.103.062893  1
2002 Hall FC, Rabinowitz JD, Busch R, Visconti KC, Belmares M, Patil NS, Cope AP, Patel S, McConnell HM, Mellins ED, Sonderstrup G. Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes. European Journal of Immunology. 32: 662-70. PMID 11857340 DOI: 10.1002/1521-4141(200203)32:3<662::AID-IMMU662>3.0.CO;2-5  1
2000 Belmares MP, Rabinowitz JD, Liu W, Mellins ED, McConnell HM. pH stability of HLA-DR4 complexes with antigenic peptides. Biochemistry. 39: 14558-66. PMID 11087411 DOI: 10.1021/bi001544g  1
2000 Kasson PM, Rabinowitz JD, Schmitt L, Davis MM, McConnell HM. Kinetics of peptide binding to the class II MHC protein I-Ek. Biochemistry. 39: 1048-58. PMID 10653650 DOI: 10.1021/bi9921337  1
1998 Rabinowitz JD, Vrljic M, Kasson PM, Liang MN, Busch R, Boniface JJ, Davis MM, McConnell HM. Formation of a highly peptide-receptive state of class II MHC. Immunity. 9: 699-709. PMID 9846491  1
1998 Boniface JJ, Rabinowitz JD, Wülfing C, Hampl J, Reich Z, Altman JD, Kantor RM, Beeson C, McConnell HM, Davis MM. Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]. Immunity. 9: 459-66. PMID 9806632 DOI: 10.1016/S1074-7613(00)80629-9  1
1998 Lee C, Liang MN, Tate KM, Rabinowitz JD, Beeson C, Jones PP, McConnell HM. Evidence that the autoimmune antigen myelin basic protein (MBP) Ac1-9 binds towards one end of the major histocompatibility complex (MHC) cleft. The Journal of Experimental Medicine. 187: 1505-16. PMID 9565642 DOI: 10.1084/jem.187.9.1505  1
1998 Rabinowitz JD, Vacchino JF, Beeson C, McConnell HM. Potentiometric measurement of intracellular redox activity Journal of the American Chemical Society. 120: 2464-2473. DOI: 10.1021/ja973560f  1
1997 Rabinowitz JD, Rigler P, Carswell-Crumpton C, Beeson C, McConnell HM. Screening for novel drug effects with a microphysiometer: a potent effect of clofilium unrelated to potassium channel blockade. Life Sciences. 61: PL87-94. PMID 9252253 DOI: 10.1016/S0024-3205(97)00543-2  1
1997 Rabinowitz JD, Tate K, Lee C, Beeson C, McConnell HM. Specific T cell recognition of kinetic isomers in the binding of peptide to class II major histocompatibility complex. Proceedings of the National Academy of Sciences of the United States of America. 94: 8702-7. PMID 9238041 DOI: 10.1073/pnas.94.16.8702  1
1997 Wülfing C, Rabinowitz JD, Beeson C, Sjaastad MD, McConnell HM, Davis MM. Kinetics and extent of T cell activation as measured with the calcium signal. The Journal of Experimental Medicine. 185: 1815-25. PMID 9151707 DOI: 10.1084/jem.185.10.1815  1
1996 Rabinowitz JD, Beeson C, Wülfing C, Tate K, Allen PM, Davis MM, McConnell HM. Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity. 5: 125-35. PMID 8769476 DOI: 10.1016/S1074-7613(00)80489-6  1
1996 Rabinowitz JD, Beeson C, Lyons DS, Davis MM, McConnell HM. Kinetic discrimination in T-cell activation. Proceedings of the National Academy of Sciences of the United States of America. 93: 1401-5. PMID 8643643 DOI: 10.1073/pnas.93.4.1401  1
Show low-probability matches.