Bruce E. Torbett - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Pathology, Molecular Biology

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 McFadden WM, Casey-Moore MC, Bare GAL, Kirby KA, Wen X, Li G, Wang H, Slack RL, Snyder AA, Lorson ZC, Kaufman IL, Cilento ME, Tedbury PR, Gembicky M, Olson AJ, ... Torbett BE, et al. Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition. Cell Chemical Biology. 31: 477-486.e7. PMID 38518746 DOI: 10.1016/j.chembiol.2024.02.012  0.372
2023 Delviks-Frankenberry KA, Ojha CR, Hermann KJ, Hu WS, Torbett BE, Pathak VK. Potent dual block to HIV-1 infection using lentiviral vectors expressing fusion inhibitor peptide mC46- and Vif-resistant APOBEC3G. Molecular Therapy. Nucleic Acids. 33: 794-809. PMID 37662965 DOI: 10.1016/j.omtn.2023.08.007  0.474
2023 Vamva E, Ozog S, Leaman DP, Yu-Hong Cheng R, Irons NJ, Ott A, Stoffers C, Khan I, Goebrecht GKE, Gardner MR, Farzan M, Rawlings DJ, Zwick MB, James RG, Torbett BE. A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin. Molecular Therapy. Methods & Clinical Development. 28: 366-384. PMID 36879849 DOI: 10.1016/j.omtm.2023.02.004  0.414
2022 Shah R, Gallardo CM, Jung YH, Clock B, Dixon JR, McFadden WM, Majumder K, Pintel DJ, Corces VG, Torbett BE, Tedbury PR, Sarafianos SG. Activation of HIV-1 proviruses increases downstream chromatin accessibility. Iscience. 25: 105490. PMID 36505924 DOI: 10.1016/j.isci.2022.105490  0.421
2022 Gallardo CM, Nguyen AT, Routh AL, Torbett BE. Selective ablation of 3' RNA ends and processive RTs facilitate direct cDNA sequencing of full-length host cell and viral transcripts. Nucleic Acids Research. PMID 35736235 DOI: 10.1093/nar/gkac516  0.308
2022 Chupradit K, Khamaikawin W, Sakkhachornphop S, Puaninta C, Torbett BE, Borwornpinyo S, Hongeng S, Wattanapanitch M, Tayapiwatana C. Engineered Zinc Finger Protein Targeting 2LTR Inhibits HIV Integration in Hematopoietic Stem and Progenitor Cell-Derived Macrophages: In Vitro Study. International Journal of Molecular Sciences. 23. PMID 35216446 DOI: 10.3390/ijms23042331  0.509
2021 Zhuang S, Torbett BE. Interactions of HIV-1 Capsid with Host Factors and Their Implications for Developing Novel Therapeutics. Viruses. 13. PMID 33807824 DOI: 10.3390/v13030417  0.365
2021 Deng Y, Hammond JA, Pauszek R, Ozog S, Chai I, Rabuck-Gibbons J, Lamichhane R, Henderson S, Millar DP, Torbett BE, Williamson JR. Discrimination between Functional and Non-functional Cellular Gag Complexes Involved in HIV-1 Assembly. Journal of Molecular Biology. 166842. PMID 33539875 DOI: 10.1016/j.jmb.2021.166842  0.305
2020 Deng Y, Hammond JA, Pauszek RF, Chai I, Ozog ST, Millar DP, Torbett BE, Williamson JR. Cellular Gag-Containing Complexes and HIV Assembly Biophysical Journal. 118: 201a. DOI: 10.1016/J.Bpj.2019.11.1211  0.459
2019 Delviks-Frankenberry KA, Ackerman D, Timberlake ND, Hamscher M, Nikolaitchik OA, Hu WS, Torbett BE, Pathak VK. Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G. Molecular Therapy. Nucleic Acids. 18: 1023-1038. PMID 31778955 DOI: 10.1016/J.Omtn.2019.10.024  0.579
2019 Ozog S, Timberlake ND, Hermann K, Garijo O, Haworth KG, Shi G, Glinkerman CM, Schefter LE, D'Souza S, Simpson E, Sghia-Hughes G, Carillo RR, Boger DL, Kiem HP, Slukvin I, ... ... Torbett BE, et al. Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes. Blood. PMID 31416800 DOI: 10.1182/Blood.2019000040  0.391
2019 Ozog S, Chen CX, Simpson E, Garijo O, Timberlake ND, Minder P, Verhoeyen E, Torbett BE. CD46 Null Packaging Cell Line Improves Measles Lentiviral Vector Production and Gene Delivery to Hematopoietic Stem and Progenitor Cells. Molecular Therapy. Methods & Clinical Development. 13: 27-39. PMID 30603655 DOI: 10.1016/J.Omtm.2018.11.006  0.408
2018 Shi G, Ozog S, Torbett BE, Compton AA. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301809 DOI: 10.1073/Pnas.1811892115  0.387
2018 Jin J, Britschgi A, Schläfli AM, Humbert M, Shan-Krauer D, Batliner J, Federzoni EA, Ernst M, Torbett BE, Yousefi S, Simon HU, Tschan MP. Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative Medicine and Cellular Longevity. 2018: 1482795. PMID 29743969 DOI: 10.1155/2018/1482795  0.362
2018 Iwasaki M, Minder P, Caì Y, Kuhn JH, Yates JR, Torbett BE, de la Torre JC. Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses. Plos Pathogens. 14: e1006892. PMID 29462184 DOI: 10.1371/Journal.Ppat.1006892  0.369
2018 Humbert M, Tschan MP, Haimovici A, Torbett BE, Niklaus N. A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells Blood. 132: 1347-1347. DOI: 10.1182/Blood-2018-99-112797  0.319
2018 Seiler K, Minder P, Mashimo I, Humbert M, Simpson E, Tschan MP, Torbett BE. Hexokinase Proteins Impart Distinct Functions in Myeloid Development and Cell Death Blood. 132: 5088-5088. DOI: 10.1182/Blood-2018-99-112145  0.384
2017 Heffner GC, Bonner M, Christiansen L, Pierciey FJ, Campbell D, Smurnyy Y, Zhang W, Hamel A, Shaw S, Lewis G, Goss KA, Garijo O, Torbett BE, Horton H, Finer MH, et al. Prostaglandin E2 Increases Lentiviral Vector Transduction Efficiency of Adult Human Hematopoietic Stem and Progenitor Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29102562 DOI: 10.1016/J.Ymthe.2017.09.025  0.443
2017 Flynn WF, Haldane A, Torbett BE, Levy RM. Inference of Epistatic Effects Leading to Entrenchment and Drug Resistance in HIV-1 Protease. Molecular Biology and Evolution. PMID 28369521 DOI: 10.1093/Molbev/Msx095  0.397
2017 Haimovici A, Humbert M, Federzoni EA, Shan-Krauer D, Brunner T, Frese S, Kaufmann T, Torbett BE, Tschan MP. PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell Death and Differentiation. PMID 28362429 DOI: 10.1038/Cdd.2017.40  0.393
2016 Baird A, Deng C, Eliceiri M, Haghi F, Dang X, Coimbra R, Costantini TW, Torbett BE, Eliceiri BP. Mice engrafted with human hematopoietic stem cells supports a human myeloid cell inflammatory response in vivo. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. PMID 27663454 DOI: 10.1111/Wrr.12471  0.362
2016 Weber MR, Zuka M, Lorger M, Tschan M, Torbett BE, Zijlstra A, Quigley JP, Staflin K, Eliceiri BP, Krueger JS, Marchese P, Ruggeri ZM, Felding BH. Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream. Thrombosis Research. 140: S27-36. PMID 27067975 DOI: 10.1016/S0049-3848(16)30095-0  0.31
2016 Wampfler J, Federzoni EA, Torbett BE, Fey MF, Tschan MP. The RNA binding proteins RBM38 and DND1 are repressed in AML and have a novel function in APL differentiation. Leukemia Research. 41: 96-102. PMID 26740055 DOI: 10.1016/J.Leukres.2015.12.006  0.378
2016 Timberlake N, Ozog S, D'souza S, Slukvin I, Catz SD, Snyder S, Torbett BE. 4. β-Deliverin: A Small Molecule for Improving Gene Transfer to Hematopoietic Stem Cells and Probing Mechanisms of Lentiviral Vector Restriction Molecular Therapy. 24: S2-S3. DOI: 10.1016/S1525-0016(16)32813-1  0.357
2015 Kang H, Minder P, Park MA, Mesquitta WT, Torbett BE, Slukvin II. CCR5 Disruption in Induced Pluripotent Stem Cells Using CRISPR/Cas9 Provides Selective Resistance of Immune Cells to CCR5-tropic HIV-1 Virus. Molecular Therapy. Nucleic Acids. 4: e268. PMID 26670276 DOI: 10.1038/Mtna.2015.42  0.575
2015 Routh A, Chang MW, Okulicz JF, Johnson JE, Torbett BE. CoVaMa: Co-Variation Mapper for disequilibrium analysis of mutant loci in viral populations using next-generation sequence data. Methods (San Diego, Calif.). PMID 26408523 DOI: 10.1016/J.Ymeth.2015.09.021  0.389
2015 Khamaikawin W, Saoin S, Nangola S, Chupradit K, Sakkhachornphop S, Hadpech S, Onlamoon N, Ansari AA, Byrareddy SN, Boulanger P, Hong SS, Torbett BE, Tayapiwatana C. Combined Antiviral Therapy Using Designed Molecular Scaffolds Targeting Two Distinct Viral Functions, HIV-1 Genome Integration and Capsid Assembly. Molecular Therapy. Nucleic Acids. 4: e249. PMID 26305555 DOI: 10.1038/Mtna.2015.22  0.575
2015 Tschan MP, Federzoni EA, Haimovici A, Britschgi C, Moser BA, Jin J, Reddy VA, Sheeter DA, Fischer KM, Sun P, Torbett BE. Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation. Biochimica Et Biophysica Acta. 1849: 1198-208. PMID 26187004 DOI: 10.1016/J.Bbagrm.2015.07.009  0.329
2015 Wang CX, Torbett BE. Role of the mammalian target of rapamycin pathway in lentiviral vector transduction of hematopoietic stem cells. Current Opinion in Hematology. 22: 302-8. PMID 26049750 DOI: 10.1097/Moh.0000000000000150  0.358
2015 Wampfler J, Federzoni EA, Torbett BE, Fey MF, Tschan MP. Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells. Journal of Leukocyte Biology. 98: 357-63. PMID 25990244 DOI: 10.1189/Jlb.1Ab0514-258R  0.305
2015 Federzoni EA, Gloor S, Jin J, Shan-Krauer D, Fey MF, Torbett BE, Tschan MP. Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells. Leukemia Research Reports. 4: 32-5. PMID 25984443 DOI: 10.1016/J.Lrr.2015.04.002  0.358
2015 Flynn WF, Chang MW, Tan Z, Oliveira G, Yuan J, Okulicz JF, Torbett BE, Levy RM. Deep sequencing of protease inhibitor resistant HIV patient isolates reveals patterns of correlated mutations in Gag and protease. Plos Computational Biology. 11: e1004249. PMID 25894830 DOI: 10.1371/Journal.Pcbi.1004249  0.349
2015 Mori M, Kovalenko L, Lyonnais S, Antaki D, Torbett BE, Botta M, Mirambeau G, Mély Y. Nucleocapsid Protein: A Desirable Target for Future Therapies Against HIV-1. Current Topics in Microbiology and Immunology. 389: 53-92. PMID 25749978 DOI: 10.1007/82_2015_433  0.468
2015 Barclay SL, Yang Y, Zhang S, Fong R, Barraza A, Nolta JA, Torbett BE, Abedi M, Bauer G, Anderson JS. Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells. Stem Cells (Dayton, Ohio). 33: 870-9. PMID 25524029 DOI: 10.1002/Stem.1919  0.588
2014 Garg D, Torbett BE. Advances in targeting nucleocapsid-nucleic acid interactions in HIV-1 therapy. Virus Research. 193: 135-43. PMID 25026536 DOI: 10.1016/J.Virusres.2014.07.004  0.485
2014 Wang CX, Sather BD, Wang X, Adair J, Khan I, Singh S, Lang S, Adams A, Curinga G, Kiem HP, Miao CH, Rawlings DJ, Torbett BE. Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells. Blood. 124: 913-23. PMID 24914132 DOI: 10.1182/Blood-2013-12-546218  0.434
2014 Federzoni EA, Humbert M, Torbett BE, Behre G, Fey MF, Tschan MP. CEBPA-dependent HK3 and KLF5 expression in primary AML and during AML differentiation. Scientific Reports. 4: 4261. PMID 24584857 DOI: 10.1038/Srep04261  0.349
2014 Amirache F, Lévy C, Costa C, Mangeot PE, Torbett BE, Wang CX, Nègre D, Cosset FL, Verhoeyen E. Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor. Blood. 123: 1422-4. PMID 24578496 DOI: 10.1182/Blood-2013-11-540641  0.332
2014 Humbert M, Federzoni EA, Britschgi A, Schläfli AM, Valk PJ, Kaufmann T, Haferlach T, Behre G, Simon HU, Torbett BE, Fey MF, Tschan MP. The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of Leukocyte Biology. 95: 83-93. PMID 24038216 DOI: 10.1189/Jlb.1112608  0.36
2013 Brigger D, Torbett BE, Chen J, Fey MF, Tschan MP. Inhibition of GATE-16 attenuates ATRA-induced neutrophil differentiation of APL cells and interferes with autophagosome formation. Biochemical and Biophysical Research Communications. 438: 283-8. PMID 23891751 DOI: 10.1016/J.Bbrc.2013.07.056  0.387
2013 Tiefenbrunn T, Forli S, Baksh MM, Chang MW, Happer M, Lin YC, Perryman AL, Rhee JK, Torbett BE, Olson AJ, Elder JH, Finn MG, Stout CD. Small molecule regulation of protein conformation by binding in the Flap of HIV protease. Acs Chemical Biology. 8: 1223-31. PMID 23540839 DOI: 10.1021/Cb300611P  0.34
2013 Chang MW, Oliveira G, Yuan J, Okulicz JF, Levy S, Torbett BE. Rapid deep sequencing of patient-derived HIV with ion semiconductor technology. Journal of Virological Methods. 189: 232-4. PMID 23384677 DOI: 10.1016/J.Jviromet.2013.01.019  0.396
2013 Joshi P, Sloan B, Torbett BE, Stoddart CA. Heat shock protein 90AB1 and hyperthermia rescue infectivity of HIV with defective cores. Virology. 436: 162-72. PMID 23200770 DOI: 10.1016/J.Virol.2012.11.005  0.509
2012 Yuan J, Wang J, Crain K, Fearns C, Kim KA, Hua KL, Gregory PD, Holmes MC, Torbett BE. Zinc-finger Nuclease Editing of Human cxcr4 Promotes HIV-1 CD4(+) T Cell Resistance and Enrichment. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 849-859. PMID 28160615 DOI: 10.1038/mt.2011.310  0.513
2012 Schläfli AM, Torbett BE, Fey MF, Tschan MP. BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation. Experimental Hematology & Oncology. 1: 25. PMID 23211188 DOI: 10.1186/2162-3619-1-25  0.379
2012 Breuer S, Chang MW, Yuan J, Torbett BE. Identification of HIV-1 inhibitors targeting the nucleocapsid protein. Journal of Medicinal Chemistry. 55: 4968-77. PMID 22587465 DOI: 10.1021/Jm201442T  0.357
2012 Federzoni EA, Valk PJM, Torbett BE, Haferlach T, Löwenberg B, Fey MF, Tschan MP. PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells Blood. 119: 4963-4970. PMID 22498738 DOI: 10.1182/Blood-2011-09-378117  0.388
2012 Yuan J, Wang J, Crain K, Fearns C, Kim KA, Hua KL, Gregory PD, Holmes MC, Torbett BE. Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 849-59. PMID 22273578 DOI: 10.1038/Mt.2011.310  0.59
2012 Batliner J, Buehrer E, Federzoni EA, Jenal M, Tobler A, Torbett BE, Fey MF, Tschan MP. Transcriptional regulation of MIR29B by PU.1 (SPI1) and MYC during neutrophil differentiation of acute promyelocytic leukaemia cells. British Journal of Haematology. 157: 270-4. PMID 22145969 DOI: 10.1111/J.1365-2141.2011.08964.X  0.307
2011 Lugari A, Breuer S, Coursindel T, Opi S, Restouin A, Shi X, Nazabal A, Torbett BE, Martinez J, Collette Y, Parrot I, Arold ST, Morelli X. A specific protein disorder catalyzer of HIV-1 Nef. Bioorganic & Medicinal Chemistry. 19: 7401-6. PMID 22061824 DOI: 10.1016/J.Bmc.2011.10.051  0.457
2011 Chang MW, Torbett BE. Accessory mutations maintain stability in drug-resistant HIV-1 protease. Journal of Molecular Biology. 410: 756-60. PMID 21762813 DOI: 10.1016/J.Jmb.2011.03.038  0.42
2011 Lin YC, Perryman AL, Olson AJ, Torbett BE, Elder JH, Stout CD. Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease. Acta Crystallographica. Section D, Biological Crystallography. 67: 540-8. PMID 21636894 DOI: 10.1107/S0907444911011681  0.476
2011 Breuer S, Sepulveda H, Chen Y, Trotter J, Torbett BE. A cleavage enzyme-cytometric bead array provides biochemical profiling of resistance mutations in HIV-1 Gag and protease. Biochemistry. 50: 4371-81. PMID 21452835 DOI: 10.1021/Bi200031M  0.352
2011 Batliner J, Mancarelli MM, Jenal M, Reddy VA, Fey MF, Torbett BE, Tschan MP. CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation. Molecular Immunology. 48: 714-9. PMID 21094529 DOI: 10.1016/J.Molimm.2010.10.016  0.379
2010 Chang MW, Ayeni C, Breuer S, Torbett BE. Virtual screening for HIV protease inhibitors: a comparison of AutoDock 4 and Vina. Plos One. 5: e11955. PMID 20694138 DOI: 10.1371/Journal.Pone.0011955  0.414
2010 Chang MW, Giffin MJ, Muller R, Savage J, Lin YC, Hong S, Jin W, Whitby LR, Elder JH, Boger DL, Torbett BE. Identification of broad-based HIV-1 protease inhibitors from combinatorial libraries. The Biochemical Journal. 429: 527-32. PMID 20507280 DOI: 10.1042/Bj20091645  0.423
2010 Lin YC, Torbett BE, Elder JH. Generation of infectious feline immunodeficiency virus (FIV) encoding FIV/human immunodeficiency virus chimeric protease. Journal of Virology. 84: 6799-809. PMID 20410281 DOI: 10.1128/Jvi.00294-10  0.469
2009 Grant CK, Fink EA, Sundstrom M, Torbett BE, Elder JH. Improved health and survival of FIV-infected cats is associated with the presence of autoantibodies to the primary receptor, CD134. Proceedings of the National Academy of Sciences of the United States of America. 106: 19980-5. PMID 19901342 DOI: 10.1073/Pnas.0911307106  0.362
2009 Luxen S, Noack D, Frausto M, Davanture S, Torbett BE, Knaus UG. Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells. Journal of Cell Science. 122: 1238-47. PMID 19339556 DOI: 10.1242/Jcs.044123  0.309
2008 Giffin MJ, Heaslet H, Brik A, Lin YC, Cauvi G, Wong CH, McRee DE, Elder JH, Stout CD, Torbett BE. A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant. Journal of Medicinal Chemistry. 51: 6263-70. PMID 18823110 DOI: 10.1021/Jm800149M  0.369
2008 Fang J, Menon M, Zhang D, Torbett B, Oxburgh L, Tschan M, Houde E, Wojchowski DM. Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2. Blood. 112: 886-90. PMID 18535204 DOI: 10.1182/Blood-2008-02-138909  0.35
2008 Blancafort P, Tschan MP, Bergquist S, Guthy D, Brachat A, Sheeter DA, Torbett BE, Erdmann D, Barbas CF. Modulation of drug resistance by artificial transcription factors. Molecular Cancer Therapeutics. 7: 688-97. PMID 18319335 DOI: 10.1158/1535-7163.Mct-07-0381  0.308
2008 Britschgi C, Jenal M, Rizzi M, Mueller BU, Torbett BE, Andres AC, Tobler A, Fey MF, Tschan MP. HIC1 tumour suppressor gene is suppressed in acute myeloid leukaemia and induced during granulocytic differentiation. British Journal of Haematology. 141: 179-87. PMID 18318772 DOI: 10.1111/J.1365-2141.2008.06992.X  0.396
2008 Tschan MP, Reddy VA, Ress A, Arvidsson G, Fey MF, Torbett BE. PU.1 binding to the p53 family of tumor suppressors impairs their transcriptional activity Oncogene. 27: 3489-3493. PMID 18193090 DOI: 10.1038/Sj.Onc.1211004  0.353
2008 Mancarelli MM, Frusciante LC, Cauvi GF, Rossi CD, Torbett BE. C/EBPalpha Is a Key Transcriptional Regulator of the Triggering Receptor on Myeloid Cells-2 Gene Blood. 112: 4762-4762. DOI: 10.1182/Blood.V112.11.4762.4762  0.33
2008 Jenal M, Reddy VA, Laedrach J, Shan D, Tobler A, Torbett BE, Fey MF, Tschan MP. The Anti-Apoptotic Gene BCL2A1 Is Transcriptionally Regulated by PU.1 Blood. 112: 3579-3579. DOI: 10.1182/Blood.V112.11.3579.3579  0.429
2007 Yeamans C, Wang D, Paz-Priel I, Torbett BE, Tenen DG, Friedman AD. C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment. Blood. 110: 3136-42. PMID 17671233 DOI: 10.1182/Blood-2007-03-080291  0.327
2007 Heaslet H, Rosenfeld R, Giffin M, Lin YC, Tam K, Torbett BE, Elder JH, McRee DE, Stout CD. Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallographica. Section D, Biological Crystallography. 63: 866-75. PMID 17642513 DOI: 10.1107/S0907444907029125  0.436
2007 Rizzi M, Tschan MP, Britschgi C, Britschgi A, Hügli B, Grob TJ, Leupin N, Mueller BU, Simon HU, Ziemiecki A, Torbett BE, Fey MF, Tobler A. The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. Journal of Leukocyte Biology. 81: 1599-608. PMID 17347302 DOI: 10.1189/Jlb.0606400  0.414
2007 Heaslet H, Lin YC, Tam K, Torbett BE, Elder JH, Stout CD. Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3. Retrovirology. 4: 1. PMID 17212810 DOI: 10.1186/1742-4690-4-1  0.445
2006 Manuel ER, Charini WA, Sen P, Peyerl FW, Kuroda MJ, Schmitz JE, Autissier P, Sheeter DA, Torbett BE, Letvin NL. Contribution of T-cell receptor repertoire breadth to the dominance of epitope-specific CD8+ T-lymphocyte responses. Journal of Virology. 80: 12032-40. PMID 17035327 DOI: 10.1128/Jvi.01479-06  0.386
2006 Lin YC, Brik A, de Parseval A, Tam K, Torbett BE, Wong CH, Elder JH. Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system. Journal of Virology. 80: 7832-43. PMID 16873240 DOI: 10.1128/Jvi.00374-06  0.507
2006 Swan CH, Torbett BE. Can gene delivery close the door to HIV-1 entry after escape? Journal of Medical Primatology. 35: 236-47. PMID 16872287 DOI: 10.1111/J.1600-0684.2006.00172.X  0.805
2006 Swan CH, Bühler B, Steinberger P, Tschan MP, Barbas CF, Torbett BE. T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery. Gene Therapy. 13: 1480-92. PMID 16738691 DOI: 10.1038/Sj.Gt.3302801  0.819
2006 Cirulli V, Zalatan J, McMaster M, Prinsen R, Salomon DR, Ricordi C, Torbett BE, Meda P, Crisa L. The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G. Diabetes. 55: 1214-22. PMID 16644675 DOI: 10.2337/Db05-0731  0.318
2006 Heaslet H, Kutilek V, Morris GM, Lin YC, Elder JH, Torbett BE, Stout CD. Structural insights into the mechanisms of drug resistance in HIV-1 protease NL4-3. Journal of Molecular Biology. 356: 967-81. PMID 16403521 DOI: 10.1016/J.Jmb.2005.11.094  0.469
2006 Fang J, Menon MP, Zhang D, Tschan M, Torbett B, Pramanik N, Houde E, Wojchowski DM. Transgenic GATA1ie3.9int - DAPK2 Mice Exhibit Low-Grade Anemia, Deficient Stress Erythropoiesis, and Compromised Erythroblast Survival. Blood. 108: 1288-1288. DOI: 10.1182/Blood.V108.11.1288.1288  0.306
2006 Foos GE, Fischer KM, Savage J, Reddy V, Torbett BE. Identification of PU.1 Target Genes That Are Dependent on Specific Functional Domains of the Transcription Factor PU.1. Blood. 108: 1174-1174. DOI: 10.1182/Blood.V108.11.1174.1174  0.356
2006 Swan CH, Chatterji U, Gallay P, Picker LJ, Torbett BE. 760. Overcoming Rhesus Macaque Endogenous Restriction Factors during HIV-1 Vector Transduction Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.844  0.828
2005 Swan CH, Chatterji U, Gallay P, Torbett BE. A Cyclophilin A-Independent Capsid Motif Renders HIV-1 Derived Vectors More Efficient at Transducing Human Cells. Blood. 106: 5531-5531. DOI: 10.1182/Blood.V106.11.5531.5531  0.825
2005 Fang J, Menon MP, Tschan M, Torbett B, Wojchowski D. Death-Associated Protein Kinase-2 (DAPK2) Potentiates Erythroid Progenitor Cell Apoptosis in Response to Cisplatin, and Cytokine Withdrawal. Blood. 106: 3537-3537. DOI: 10.1182/Blood.V106.11.3537.3537  0.376
2005 Rizzi M, Britschgi C, Tschan MP, Grob TJ, Huegli B, Leupin N, Mueller BU, Ziemiecki A, Torbett BE, Fey MF, Tobler A. Enhancing Neutrophil Differentiation - A Novel Role for the Death-Associated Protein Kinase 2 (DAPK2). Blood. 106: 1348-1348. DOI: 10.1182/Blood.V106.11.1348.1348  0.401
2005 Swan CH, Tschan MP, Barbas CF, Torbett BE. 1001. Knockdown of CXCR4 Expression Sufficient for Blocking HIV-1-Infection Requires Combinatorial Intrabody and siRNA Mediated HIV-1 Vector Gene Delivery Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.548  0.83
2005 Swan CH, Fischer KM, Bühler B, Tschan MP, Barbas CF, Torbett BE. 973. Targeting of CCR5 through Intrabody Mediated HIV-1 Vector Gene Delivery Is Sufficient for Blocking HIV-1-Infection and Confers a T-Cell Survival and Growth Advantage Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.516  0.831
2004 de Rozières S, Swan CH, Sheeter DA, Clingerman KJ, Lin YC, Huitron-Resendiz S, Henriksen S, Torbett BE, Elder JH. Assessment of FIV-C infection of cats as a function of treatment with the protease inhibitor, TL-3. Retrovirology. 1: 38. PMID 15555065 DOI: 10.1186/1742-4690-1-38  0.765
2004 Segal DJ, Gonçalves J, Eberhardy S, Swan CH, Torbett BE, Li X, Barbas CF. Attenuation of HIV-1 Replication in Primary Human Cells with a Designed Zinc Finger Transcription Factor Journal of Biological Chemistry. 279: 14509-14519. PMID 14734553 DOI: 10.1074/Jbc.M400349200  0.818
2004 Weber MR, O’Sullivan D, Tschan MP, Torbett BE, Zijlstra A, Quigley JP, Felding-Habermann B. Understanding Hematogenous Breast Cancer Metastasis: Tumor Cell Integrin Activation Matters. Blood. 104: 2613-2613. DOI: 10.1182/Blood.V104.11.2613.2613  0.366
2004 Swan CH, Tschan MP, Barbas CF, Torbett BE. Development of a Unique siRNA and Intrabody Combinatorial HIV-1 Vector to Knockdown CXCR4 and Protect Cells from HIV-1 Challenge. Blood. 104: 1757-1757. DOI: 10.1182/Blood.V104.11.1757.1757  0.829
2004 Fischer KM, Just ML, Barbas CF, Torbett BE. CD34+ Cell Derived Macrophages Are Protected from HIV-1 Challenge by Intrabody-Mediated Reduction of CCR5. Blood. 104: 1756-1756. DOI: 10.1182/Blood.V104.11.1756.1756  0.593
2004 Swan CH, Buhler B, Tschan MP, Barbas CF, Torbett BE. Lentiviral CCR5 Intrabody Gene Delivery Provides Protection and Enrichment during CCR5-Tropic Infection. Blood. 104: 1755-1755. DOI: 10.1182/Blood.V104.11.1755.1755  0.836
2003 Kutilek VD, Sheeter DA, Elder JH, Torbett BE. Is resistance futile? Current Drug Targets. Infectious Disorders. 3: 295-309. PMID 14754431 DOI: 10.2174/1568005033481079  0.453
2003 Tschan MP, Fischer KM, Fung VS, Pirnia F, Borner MM, Fey MF, Tobler A, Torbett BE. Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns. The Journal of Biological Chemistry. 278: 42750-60. PMID 12917399 DOI: 10.1074/Jbc.M307067200  0.435
2003 Gombart AF, Kwok SH, Anderson KL, Yamaguchi Y, Torbett BE, Koeffler HP. Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBP epsilon and PU.1. Blood. 101: 3265-73. PMID 12515729 DOI: 10.1182/Blood-2002-04-1039  0.344
2002 Torbett BE. Reporter genes: too much of a good thing? The Journal of Gene Medicine. 4: 478-9. PMID 12221640 DOI: 10.1002/Jgm.323  0.367
2002 Manchester M, Smith KA, Eto DS, Perkin HB, Torbett BE. Targeting and hematopoietic suppression of human CD34+ cells by measles virus. Journal of Virology. 76: 6636-42. PMID 12050376 DOI: 10.1128/Jvi.76.13.6636-6642.2002  0.422
2002 Beutler E, West C, Torbett BE, Deguchi H. A chimeric mouse model of Gaucher disease. Molecular Medicine. 8: 247-250. DOI: 10.1007/Bf03402150  0.318
2001 Bühler B, Lin Y, Morris G, Olson AJ, Wong C, Richman DD, Elder JH, Torbett BE. Viral evolution in response to the broad-based retroviral protease inhibitor TL-3 Journal of Virology. 75: 9502-9508. PMID 11533212 DOI: 10.1128/Jvi.75.19.9502-9508.2001  0.342
2001 Anderson KL, Nelson SL, Perkin HB, Smith KA, Klemsz MJ, Torbett BE. PU.1 is a lineage-specific regulator of tyrosine phosphatase CD45. The Journal of Biological Chemistry. 276: 7637-42. PMID 11114304 DOI: 10.1074/Jbc.M009133200  0.416
2000 Zhang P, Zhang X, Iwama A, Yu C, Smith KA, Mueller BU, Narravula S, Torbett BE, Orkin SH, Tenen DG. PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood. 96: 2641-8. PMID 11023493 DOI: 10.1182/Blood.V96.8.2641  0.326
2000 Laan LJWvd, Lockey C, Griffeth BC, Frasier FS, Wilson CA, Onions DE, Hering BJ, Long Z, Otto E, Torbett BE, Salomon DR. Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice. Nature. 407: 90-94. PMID 10993079 DOI: 10.1038/35024089  0.353
2000 Mayrand S, Healy PA, Torbett BE, Green WR. Anti-Gag Cytolytic T Lymphocytes Specific for an Alternative Translational Reading Frame-Derived Epitope and Resistance Versus Susceptibility to Retrovirus-Induced Murine AIDS in F1 Mice Virology. 272: 438-449. PMID 10873788 DOI: 10.1006/Viro.2000.0339  0.317
2000 Anderson KL, Perkin H, Surh CD, Venturini S, Maki RA, Torbett BE. Transcription Factor PU.1 Is Necessary for Development of Thymic and Myeloid Progenitor-Derived Dendritic Cells Journal of Immunology. 164: 1855-1861. PMID 10657634 DOI: 10.4049/Jimmunol.164.4.1855  0.39
2000 Steinberger P, Andris-Widhopf J, Bühler B, Torbett BE, Barbas CF. Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion Proceedings of the National Academy of Sciences of the United States of America. 97: 805-810. PMID 10639161 DOI: 10.1073/Pnas.97.2.805  0.582
2000 Pelletier AJ, Laan LJWvd, Hildbrand P, Siani MA, Thompson DA, Dawson PE, Torbett BE, Salomon DR. Presentation of chemokine SDF-1α by fibronectin mediates directed migration of T cells Blood. 96: 2682-2690. DOI: 10.1182/Blood.V96.8.2682.H8002682_2682_2690  0.31
1999 Crisa L, Cirulli V, Smith KA, Ellisman MH, Torbett BE, Salomon DR. Human cord blood progenitors sustain thymic T-cell development and a novel form of angiogenesis. Blood. 94: 3928-40. PMID 10572110 DOI: 10.1182/Blood.V94.11.3928  0.361
1999 Miyoshi H, Smith KA, Mosier DE, Verma IM, Torbett BE. Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors. Science (New York, N.Y.). 283: 682-6. PMID 9924027 DOI: 10.1126/Science.283.5402.682  0.519
1999 Anderson KL, Smith KA, Perkin H, Hermanson G, Anderson C, Jolly DJ, Maki RA, Torbett BE. PU.1 and the Granulocyte- and Macrophage Colony-Stimulating Factor Receptors Play Distinct Roles in Late-Stage Myeloid Cell Differentiation Blood. 94: 2310-2318. DOI: 10.1182/Blood.V94.7.2310.419K34_2310_2318  0.373
1998 Pedroza-Martins L, Gurney KB, Torbett BE, Uittenbogaart CH. Differential tropism and replication kinetics of human immunodeficiency virus type 1 isolates in thymocytes: coreceptor expression allows viral entry, but productive infection of distinct subsets is determined at the postentry level. Journal of Virology. 72: 9441-52. PMID 9811677 DOI: 10.1128/Jvi.72.12.9441-9452.1998  0.505
1998 Lee T, Laco GS, Torbett BE, Fox HS, Lerner DL, Elder JH, Wong CH. Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 939-44. PMID 9448264 DOI: 10.1073/Pnas.95.3.939  0.461
1998 Anderson KL, Smith KA, Pio F, Torbett BE, Maki RA. Neutrophils Deficient in PU.1 Do Not Terminally Differentiate or Become Functionally Competent Blood. 92: 1576-1585. DOI: 10.1182/Blood.V92.5.1576.417K29_1576_1585  0.363
1998 Anderson KL, Smith KA, Conners K, McKercher SR, Maki RA, Torbett BE. Myeloid Development Is Selectively Disrupted in PU.1 Null Mice Blood. 91: 3702-3710. DOI: 10.1182/Blood.V91.10.3702.3702_3702_3710  0.384
1996 McKercher SR, Torbett BE, Anderson KL, Henkel GW, Vestal DJ, Baribault H, Klemsz M, Feeney AJ, Wu GE, Paige CJ, Maki RA. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. The Embo Journal. 15: 5647-5658. DOI: 10.1002/J.1460-2075.1996.Tb00949.X  0.378
1994 Reinhardt B, Torbett BE, Gulizia RJ, Reinhardt PP, Spector SA, Mosier DE. Human immunodeficiency virus type 1 infection of neonatal severe combined immunodeficient mice xenografted with human cord blood cells. Aids Research and Human Retroviruses. 10: 131-41. PMID 8198867 DOI: 10.1089/Aid.1994.10.131  0.461
1994 Ucker DS, Hebshi LD, Beomquist JF, Torbett BE. Physiological T-cell death: Susceptibility is modulated by activation, aging, and transformation, but the mechanism is constant Immunological Reviews. 273-299. PMID 7698797 DOI: 10.1111/J.1600-065X.1994.Tb00893.X  0.342
1993 Mosier DE, Stell KL, Gulizia RJ, Torbett BE, Gilmore GL. Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation. Journal of Experimental Medicine. 177: 191-194. PMID 8418200 DOI: 10.1084/Jem.177.1.191  0.345
1993 Mosier DE, Gulizia RJ, MacIsaac PD, Torbett BE, Levy JA. Rapid loss of CD4+ T cells in human-PBL-SCID mice by noncytopathic HIV isolates. Science (New York, N.Y.). 260: 689-92. PMID 8097595 DOI: 10.1126/Science.8097595  0.575
1993 Gahring LC, Ernst DN, Romball CG, Thoman ML, Torbett BE, Hobbs M, Weigle WO. The Expression of CD45RB on Antigen-Responsive CD4+ Lymphocytes: Mouse Strain Polymorphism and Different Responses to Distinct Antigens Cellular Immunology. 148: 269-282. PMID 7684327 DOI: 10.1006/Cimm.1993.1111  0.356
1992 Wineman J, Gilmore G, Gritzmacher C, Torbett B, Muller-Sieburg C. CD4 is expressed on murine pluripotent hematopoietic stem cells. Blood. 80: 1717-1724. DOI: 10.1182/Blood.V80.7.1717.Bloodjournal8071717  0.376
1991 Hobbs MV, Ernst DN, Torbett BE, Glasebrook AL, Rehse MA, McQuitty DN, Thoman ML, Bottomly K, Rothermel AL, Noonan DJ, Weigle WO. Cell proliferation and cytokine production by CD4+ cells from old mice Journal of Cellular Biochemistry. 46: 312-320. PMID 1684583 DOI: 10.1002/Jcb.240460406  0.328
1988 Torbett BE, Clark WR. The role of accessory molecules in T-helper activation induced by antigen, lectin, or CD3 antibodies Cellular Immunology. 115: 352-362. PMID 2970307 DOI: 10.1016/0008-8749(88)90187-6  0.348
1986 Torbett BE, Skidmore B, Clark WR. Multiple pathways for antigen-independent activation of a T helper hybridoma European Journal of Immunology. 16: 933-938. PMID 2943596 DOI: 10.1002/Eji.1830160810  0.314
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