Ruth J. Muschel - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology, Oncology, Pathology, Molecular Biology

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vermeer JAF, Ient J, Markelc B, Kaeppler J, Barbeau LMO, Groot AJ, Muschel RJ, Vooijs MA. A lineage-tracing tool to map the fate of hypoxic tumour cells. Disease Models & Mechanisms. PMID 32571767 DOI: 10.1242/Dmm.044768  0.367
2017 D'Costa Z, Jones K, Azad A, van Stiphout R, Lim SY, Gomes AL, Kinchesh P, Smart SC, McKenna WG, Buffa FM, Sansom OJ, Muschel RJ, O'Neill E, Fokas E. Gemcitabine-induced TIMP1 attenuates therapy response and promotes tumor growth and liver metastasis in pancreatic cancer. Cancer Research. PMID 28765154 DOI: 10.1158/0008-5472.CAN-16-2833  0.312
2016 Lim SY, Yuzhalin AE, Gordon-Weeks AN, Muschel RJ. Tumor-infiltrating monocytes/macrophages promote tumor invasion and migration by upregulating S100A8 and S100A9 expression in cancer cells. Oncogene. PMID 27086923 DOI: 10.1038/onc.2016.107  0.371
2015 Lim SY, Gordon-Weeks A, Allen D, Kersemans V, Beech J, Smart S, Muschel RJ. Cd11b(+) myeloid cells support hepatic metastasis through down-regulation of angiopoietin-like 7 in cancer cells. Hepatology (Baltimore, Md.). 62: 521-33. PMID 25854806 DOI: 10.1002/hep.27838  0.324
2013 Lim SY, Gordon-Weeks AN, Zhao L, Tapmeier TT, Im JH, Cao Y, Beech J, Allen D, Smart S, Muschel RJ. Recruitment of myeloid cells to the tumor microenvironment supports liver metastasis. Oncoimmunology. 2: e23187. PMID 23802071 DOI: 10.4161/onci.23187  0.323
2013 Ferjančič Š, Gil-Bernabé AM, Hill SA, Allen PD, Richardson P, Sparey T, Savory E, McGuffog J, Muschel RJ. VCAM-1 and VAP-1 recruit myeloid cells that promote pulmonary metastasis in mice. Blood. 121: 3289-97. PMID 23407548 DOI: 10.1182/blood-2012-08-449819  0.373
2012 Fokas E, Prevo R, Pollard JR, Reaper PM, Charlton PA, Cornelissen B, Vallis KA, Hammond EM, Olcina MM, Gillies McKenna W, Muschel RJ, Brunner TB. Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation. Cell Death & Disease. 3: e441. PMID 23222511 DOI: 10.1038/Cddis.2012.181  0.403
2012 Gil-Bernabé AM, Ferjancic S, Tlalka M, Zhao L, Allen PD, Im JH, Watson K, Hill SA, Amirkhosravi A, Francis JL, Pollard JW, Ruf W, Muschel RJ. Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice. Blood. 119: 3164-75. PMID 22327225 DOI: 10.1182/Blood-2011-08-376426  0.341
2011 Phipps LE, Hino S, Muschel RJ. Targeting cell spreading: a method of sensitizing metastatic tumor cells to TRAIL-induced apoptosis. Molecular Cancer Research : McR. 9: 249-58. PMID 21296861 DOI: 10.1158/1541-7786.MCR-11-0021  0.322
2010 Higgins GS, Prevo R, Lee YF, Helleday T, Muschel RJ, Taylor S, Yoshimura M, Hickson ID, Bernhard EJ, McKenna WG. A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown. Cancer Research. 70: 2984-93. PMID 20233878 DOI: 10.1158/0008-5472.CAN-09-4040  0.315
2010 Yeung TM, Gandhi SC, Wilding JL, Muschel R, Bodmer WF. Cancer stem cells from colorectal cancer-derived cell lines. Proceedings of the National Academy of Sciences of the United States of America. 107: 3722-7. PMID 20133591 DOI: 10.1073/Pnas.0915135107  0.388
2009 Qian B, Deng Y, Im JH, Muschel RJ, Zou Y, Li J, Lang RA, Pollard JW. A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. Plos One. 4: e6562. PMID 19668347 DOI: 10.1371/Journal.Pone.0006562  0.388
2009 Carbonell WS, Ansorge O, Sibson N, Muschel R. The vascular basement membrane as "soil" in brain metastasis. Plos One. 4: e5857. PMID 19516901 DOI: 10.1371/Journal.Pone.0005857  0.368
2008 O'Donnell RK, Feldman M, Mick R, Muschel RJ. Immunohistochemical method identifies lymphovascular invasion in a majority of oral squamous cell carcinomas and discriminates between blood and lymphatic vessel invasion. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 56: 803-10. PMID 18505934 DOI: 10.1369/Jhc.2008.950790  0.716
2007 O'Donnell RK, Mick R, Feldman M, Hino S, Wang Y, Brose MS, Muschel RJ. Distribution of dendritic cell subtypes in primary oral squamous cell carcinoma is inconsistent with a functional response. Cancer Letters. 255: 145-52. PMID 17574329 DOI: 10.1016/J.Canlet.2007.04.003  0.716
2006 Lubbe WJ, Zhou ZY, Fu W, Zuzga D, Schulz S, Fridman R, Muschel RJ, Waldman SA, Pitari GM. Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1876-82. PMID 16551873 DOI: 10.1158/1078-0432.Ccr-05-2686  0.431
2005 O'Donnell RK, Kupferman M, Wei SJ, Singhal S, Weber R, O'Malley B, Cheng Y, Putt M, Feldman M, Ziober B, Muschel RJ. Gene expression signature predicts lymphatic metastasis in squamous cell carcinoma of the oral cavity. Oncogene. 24: 1244-51. PMID 15558013 DOI: 10.1038/Sj.Onc.1208285  0.721
2004 Im JH, Fu W, Wang H, Bhatia SK, Hammer DA, Kowalska MA, Muschel RJ. Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation. Cancer Research. 64: 8613-9. PMID 15574768 DOI: 10.1158/0008-5472.Can-04-2078  0.448
2004 Gupta AK, Soto DE, Feldman MD, Goldsmith JD, Mick R, Hahn SM, Machtay M, Muschel RJ, McKenna WG. Signaling pathways in NSCLC as a predictor of outcome and response to therapy. Lung. 182: 151-62. PMID 15526754 DOI: 10.1007/S00408-004-0310-8  0.327
2004 Kim JW, Wong CW, Goldsmith JD, Song C, Fu W, Allion MB, Herlyn M, Al-Mehdi AB, Muschel RJ. Rapid apoptosis in the pulmonary vasculature distinguishes non-metastatic from metastatic melanoma cells. Cancer Letters. 213: 203-12. PMID 15327836 DOI: 10.1016/J.Canlet.2004.03.042  0.653
2004 DeClerck YA, Mercurio AM, Stack MS, Chapman HA, Zutter MM, Muschel RJ, Raz A, Matrisian LM, Sloane BF, Noel A, Hendrix MJ, Coussens L, Padarathsingh M. Proteases, extracellular matrix, and cancer: a workshop of the path B study section. The American Journal of Pathology. 164: 1131-9. PMID 15039201 DOI: 10.1016/S0002-9440(10)63200-2  0.432
2004 Wang H, Fu W, Im JH, Zhou Z, Santoro SA, Iyer V, DiPersio CM, Yu QC, Quaranta V, Al-Mehdi A, Muschel RJ. Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis. The Journal of Cell Biology. 164: 935-41. PMID 15024036 DOI: 10.1083/Jcb.200309112  0.336
2004 Singhal S, Singhal S, Vachani A, Kupferman M, Powell C, Gaffney P, Muschel R, Albelda S, Kaiser L. Gene expression profiling to distinguish head and neck squamous cell carcinoma metastases from primary lung squamous cell carcinoma Journal of the American College of Surgeons. 199: 66-67. DOI: 10.1016/J.Jamcollsurg.2004.05.143  0.397
2004 Wei S, O’Donnell R, Kupferman M, Weber R, Ziober B, O’Malley B, Cheng Y, Putt M, Feldman M, Muschel R. Lymphatic metastasis is predicted by gene expression signature of the primary tumor in squamous cell carcinoma of the oral cavity International Journal of Radiation Oncology*Biology*Physics. 60: S492. DOI: 10.1016/J.Ijrobp.2004.07.424  0.342
2003 Brown M, Bristow R, Glazer P, Hill R, McBride W, McKenna G, Muschel R. Comment on "Tumor response to radiotherapy regulated by endothelial cell apoptosis" (II). Science. 302: 1894-1894. PMID 14671275 DOI: 10.1126/Science.1089517  0.359
2003 McKenna WG, Muschel RJ, Gupta AK, Hahn SM, Bernhard EJ. The RAS signal transduction pathway and its role in radiation sensitivity. Oncogene. 22: 5866-75. PMID 12947393 DOI: 10.1038/Sj.Onc.1206699  0.306
2003 McKenna WG, Muschel RJ, Gupta A, Hahn S, Bernhard EJ. Signaling inhibition with radiation in colorectal cancer: clinical trials. Seminars in Oncology. 30: 56-67. PMID 12802796 DOI: 10.1016/S0093-7754(03)00126-X  0.316
2003 Gupta AK, Cerniglia GJ, Mick R, Ahmed MS, Bakanauskas VJ, Muschel RJ, McKenna WG. Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002. International Journal of Radiation Oncology, Biology, Physics. 56: 846-53. PMID 12788194 DOI: 10.1016/S0360-3016(03)00214-1  0.381
2003 Chaudhry MA, Chodosh LA, McKenna WG, Muschel RJ. Gene expression profile of human cells irradiated in G1 and G2 phases of cell cycle. Cancer Letters. 195: 221-33. PMID 12767531 DOI: 10.1016/S0304-3835(03)00154-X  0.357
2003 Qiu H, Orr FW, Jensen D, Wang HH, McIntosh AR, Hasinoff BB, Nance DM, Pylypas S, Qi K, Song C, Muschel RJ, Al-Mehdi AB. Arrest of B16 melanoma cells in the mouse pulmonary microcirculation induces endothelial nitric oxide synthase-dependent nitric oxide release that is cytotoxic to the tumor cells. The American Journal of Pathology. 162: 403-12. PMID 12547699 DOI: 10.1016/S0002-9440(10)63835-7  0.4
2003 Kim I, Fernandes A, Wu J, Gupta A, Muschel RJ, McKenna WG, Bernhard EJ. Selective inhibition of RAS signaling pathway increases the radiosensitivity in the wild type head & neck squamous cancer cell line with EGFR overexpression International Journal of Radiation Oncology Biology Physics. 57. DOI: 10.1016/S0360-3016(03)01254-9  0.326
2002 Wong CW, Song C, Grimes MM, Fu W, Dewhirst MW, Muschel RJ, Al-Mehdi AB. Intravascular location of breast cancer cells after spontaneous metastasis to the lung American Journal of Pathology. 161: 749-753. PMID 12213701 DOI: 10.1016/S0002-9440(10)64233-2  0.657
2002 McKenna WG, Muschel RJ, Gupta AK, Hahn SM, Bernhard EJ. Farnesyltransferase inhibitors as radiation sensitizers. Seminars in Radiation Oncology. 12: 27-32. PMID 12174342 DOI: 10.1053/Srao.2002.34866  0.39
2002 Chaudhry MA, Chodosh LA, McKenna WG, Muschel RJ. Gene expression profiling of HeLa cells in G1 or G2 phases. Oncogene. 21: 1934-42. PMID 11896627 DOI: 10.1038/Sj.Onc.1205264  0.324
2001 Muschel RJ, Hua J. GeneTransfection for Metastasis Research Using Animal Models Methods in Molecular Medicine. 58: 189-193. PMID 21340858 DOI: 10.1385/1-59259-137-X:189  0.421
2001 Janss AJ, Maity A, Tang CB, Muschel RJ, McKenna WG, Sutton L, Phillips PC. Decreased cyclin B1 expression contributes to G2 delay in human brain tumor cells after treatment with camptothecin. Neuro-Oncology. 3: 11-21. PMID 11305412 DOI: 10.1093/neuonc/3.1.11  0.306
2001 Wong CW, Lee A, Shientag L, Yu J, Dong Y, Kao G, Al-Mehdi AB, Bernhard EJ, Muschel RJ. Apoptosis: an early event in metastatic inefficiency. Cancer Research. 61: 333-8. PMID 11196183  0.593
2000 Kupferman ME, Fini ME, Muller WJ, Weber R, Cheng Y, Muschel RJ. Matrix metalloproteinase 9 promoter activity is induced coincident with invasion during tumor progression. American Journal of Pathology. 157: 1777-1783. PMID 11106549 DOI: 10.1016/S0002-9440(10)64815-8  0.394
2000 Cohen-Jonathan E, Muschel RJ, Gillies McKenna W, Evans SM, Cerniglia G, Mick R, Kusewitt D, Sebti SM, Hamilton AD, Oliff A, Kohl N, Gibbs JB, Bernhard EJ. Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS. Radiation Research. 154: 125-32. PMID 10931682 DOI: 10.1667/0033-7587(2000)154[0125:Fiptae]2.0.Co;2  0.411
2000 Gupta AK, Bernhard EJ, Bakanauskas VJ, Wu J, Muschel RJ, McKenna WG. RAS-Mediated Radiation Resistance is not Linked to MAP Kinase Activation in Two Bladder Carcinoma Cell Lines Radiation Research. 154: 64-72. PMID 10856967 DOI: 10.1667/0033-7587(2000)154[0064:Rmrrin]2.0.Co;2  0.329
2000 MacLachlan TK, Somasundaram K, Sgagias M, Shifman Y, Muschel RJ, Cowan KH, El-Deiry WS. BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression. The Journal of Biological Chemistry. 275: 2777-85. PMID 10644742 DOI: 10.1074/Jbc.275.4.2777  0.373
2000 Al-Mehdi AB, Tozawa K, Fisher AB, Shientag L, Lee A, Muschel RJ. Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis. Nature Medicine. 6: 100-2. PMID 10613833 DOI: 10.1038/71429  0.479
2000 Cohen-Jonathan EL, Cerniglia G, Evans SM, Koch CJ, Muschel RJ, McKenna WG, Gibbs JB, Thompson TC, Bernhard EJ. Re-oxygenation of tumors expressing activated H-ras after farnesyltransferase inhibitor L744, 832 treatment International Journal of Radiation Oncology Biology Physics. 48: 267. DOI: 10.1016/S0360-3016(00)80333-8  0.311
1999 Wu GS, Burns TF, McDonald ER, Meng RD, Kao G, Muschel R, Yen T, el-Deiry WS. Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest. Oncogene. 18: 6411-8. PMID 10597242 DOI: 10.1038/Sj.Onc.1203025  0.345
1999 Kao GD, McKenna WG, Muschel RJ. p34Cdc2 Kinase Activity Is Excluded from the Nucleus during the Radiation-induced G2 Arrest in HeLa Cells Journal of Biological Chemistry. 274: 34779-34784. PMID 10574948 DOI: 10.1074/Jbc.274.49.34779  0.313
1998 Muschel RJ, Soto DE, McKenna WG, Bernhard EJ. Radiosensitization and apoptosis. Oncogene. 17: 3359-63. PMID 9916998 DOI: 10.1038/Sj.Onc.1202580  0.336
1998 Hwang A, McKenna WG, Muschel RJ. Cell Cycle-dependent Usage of Transcriptional Start Sites A NOVEL MECHANISM FOR REGULATION OF CYCLIN B1 Journal of Biological Chemistry. 273: 31505-31509. PMID 9813064 DOI: 10.1074/Jbc.273.47.31505  0.314
1998 Janss AJ, Levow C, Bernhard EJ, Muschel RJ, McKenna WG, Sutton L, Phillips PC. Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines. Experimental Cell Research. 243: 29-38. PMID 9716446 DOI: 10.1006/Excr.1998.4122  0.407
1998 Himelstein BP, Lee EJ, Sato H, Seiki M, Muschel RJ. Tumor cell contact mediated transcriptional activation of the fibroblast matrix metalloproteinase-9 gene: involvement of multiple transcription factors including Ets and an alternating purine-pyrimidine repeat Clinical & Experimental Metastasis. 16: 169-177. PMID 9514098 DOI: 10.1023/A:1006576305405  0.394
1997 Himelstein BP, Lee EJ, Sato H, Seiki M, Muschel RJ. Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line Oncogene. 14: 1995-1998. PMID 9150367 DOI: 10.1038/Sj.Onc.1201012  0.386
1997 Maity A, Kao GD, Muschel RJ, McKenna WG. Potential molecular targets for manipulating the radiation response International Journal of Radiation Oncology Biology Physics. 37: 639-653. PMID 9112463 DOI: 10.1016/S0360-3016(96)00598-6  0.376
1996 Himelstein BP, Muschel RJ. Induction of matrix metalloproteinase 9 expression in breast carcinoma cells by a soluble factor from fibroblasts. Clinical & Experimental Metastasis. 14: 197-208. PMID 8674273 DOI: 10.1007/Bf00053892  0.372
1996 Rudoltz MS, Kao G, Blank KR, Muschel RJ, McKenna WG. Molecular Biology of the Cell Cycle: Potential for Therapeutic Applications in Radiation Oncology. Seminars in Radiation Oncology. 6: 284-294. DOI: 10.1016/S1053-4296(96)80024-5  0.345
1996 Rudoltz MS, Blank KR, Kao G, Muschel RJ, McKenna WG. Ionizing radiation and the cell cycle: A review Radiation Oncology Investigations. 4: 147-158. DOI: 10.1002/(Sici)1520-6823(1996)4:4<147::Aid-Roi1>3.0.Co;2-Y  0.35
1995 Cañete‐soler R, Gui Y, Linask KK, Muschel RJ. Developmental Expression Of Mmp-9 (Gelatinase B) Mrna In Mouse Embryos Developmental Dynamics. 204: 30-40. PMID 8563023 DOI: 10.1002/Aja.1002040105  0.305
1995 Bernhard EJ, Hagner B, Wong C, Lubenski I, Muschel RJ. The effect of E1A transfection on MMP-9 expression and metastatic potential. International Journal of Cancer. 60: 718-724. PMID 7860147 DOI: 10.1002/Ijc.2910600525  0.554
1995 Bernhard EJ, Maity A, Muschel RJ, McKenna WG. Effects of ionizing radiation on cell cycle progression. A review. Radiation and Environmental Biophysics. 34: 79-83. PMID 7652155 DOI: 10.1007/Bf01275210  0.346
1995 Soler RC, Gui Y, Linask KK, Muschel RJ. MMP-9 (gelatinase B) mRNA is expressed during mouse neurogenesis and may be associated with vascularization. Developmental Brain Research. 88: 37-52. PMID 7493406 DOI: 10.1016/0165-3806(95)00079-S  0.323
1995 Maity A, McKenna WG, Muschel RJ. Evidence for post-transcriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells. The Embo Journal. 14: 603-609. DOI: 10.1002/J.1460-2075.1995.Tb07036.X  0.311
1994 Markiewicz DA, McKenna WG, Flick MB, Maity A, Muschel RJ. The effects of radiation on the expression of a newly cloned and characterized rat cyclin B mRNA International Journal of Radiation Oncology Biology Physics. 28: 135-144. PMID 8270434 DOI: 10.1016/0360-3016(94)90151-1  0.332
1994 Bernhard EJ, Gruber SB, Muschel RJ. Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells Proceedings of the National Academy of Sciences of the United States of America. 91: 4293-4297. PMID 8183903 DOI: 10.1073/Pnas.91.10.4293  0.391
1994 Maity A, Mckenna WG, Markiewicz DA, Kunig A, Muschel RJ. Alternate polyadenylation in rodent cells results in two differentially expressed cyclin B1 mRNAs. Biochemical and Biophysical Research Communications. 202: 908-914. PMID 8048964 DOI: 10.1006/Bbrc.1994.2016  0.362
1994 Maity A, McKenna WG, Muschel RJ. The molecular basis for cell cycle delays following ionizing radiation: a review Radiotherapy and Oncology. 31: 1-13. PMID 8041894 DOI: 10.1016/0167-8140(94)90408-1  0.354
1992 Muschel RJ, Zhang HB, Iliakis G, McKenna WG. Effects of ionizing radiation on cyclin expression in HeLa cells. Radiation Research. 132: 153-157. DOI: 10.2307/3578520  0.312
1991 Muschel RJ, Zhang HB, Iliakis G, McKenna WG. Cyclin B expression in HeLa cells during the G2 block induced by ionizing radiation. Cancer Research. 51: 5113-5117. DOI: 10.1016/B978-0-12-168561-4.50651-X  0.321
1990 McKenna WG, Weiss MC, Bakanauskas VJ, Sandler H, Kelsten ML, Biaglow J, Tuttle SW, Endlich B, Ling CC, Muschel RJ. The role of the H-ras oncogene in radiation resistance and metastasis International Journal of Radiation Oncology Biology Physics. 18: 849-859. PMID 2182580 DOI: 10.1016/0360-3016(90)90407-B  0.375
1989 Liotta LA, Wewer U, Rao NC, Schiffmann E, Stracke M, Guirguis R, Thorgeirsson U, Muschel R, Sobel M. Biochemical mechanisms of tumor invasion and metastases. Advances in Experimental Medicine and Biology. 233: 161-9. PMID 2851925 DOI: 10.1007/978-1-4899-5037-6_18  0.361
1988 Muschel R, Liotta LA. Role of oncogenes in metastases. Carcinogenesis. 9: 705-710. PMID 3284663 DOI: 10.1093/Carcin/9.5.705  0.451
1986 Pozzatti R, Muschel R, Williams J, Padmanabhan R, Howard B, Liotta L, Khoury G. Primary rat embryo cells transformed by one or two oncogenes show different metastatic potentials. Science. 232: 223-227. PMID 3456644 DOI: 10.1126/Science.3456644  0.371
Show low-probability matches.