Valerie S. LeBleu, Ph.D. - Publications

Affiliations: 
2009 Harvard University, Cambridge, MA, United States 
Area:
Cell Biology

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 LeBleu VS, Kanasaki K, Lovisa S, Alge JL, Kim J, Chen Y, Teng Y, Gerami-Naini B, Sugimoto H, Kato N, Revuelta I, Grau N, Sleeman JP, Taduri G, Kizu A, et al. Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome. Life Science Alliance. 7. PMID 38561223 DOI: 10.26508/lsa.202402664  0.5
2023 Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, et al. Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. PMID 38017076 DOI: 10.1038/s41591-023-02694-w  0.469
2023 Kugeratski FG, LeBleu VS, Dowlatshahi DP, Sugimoto H, Arian KA, Fan Y, Huang L, Wells D, Lilla S, Hodge K, Zanivan S, McAndrews KM, Kalluri R. Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity. Biorxiv : the Preprint Server For Biology. PMID 37961535 DOI: 10.1101/2023.11.02.565371  0.499
2023 Mahadevan KK, LeBleu VS, Ramirez EV, Chen Y, Li B, Sockwell AM, Gagea M, Sugimoto H, Sthanam LK, Tampe D, Zeisberg M, Ying H, Jain AK, DePinho RA, Maitra A, et al. Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8 T cells. Developmental Cell. PMID 37625403 DOI: 10.1016/j.devcel.2023.07.025  0.506
2023 Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Paradiso F, et al. KRAS inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8 T cells. Cancer Cell. PMID 37625401 DOI: 10.1016/j.ccell.2023.07.002  0.52
2023 LeBleu VS, Dai J, Tsutakawa S, MacDonald BA, Alge JL, Sund M, Xie L, Sugimoto H, Tainer J, Zon LI, Kalluri R. Identification of unique α4 chain structure and conserved antiangiogenic activity of α3NC1 type IV collagen in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 37002899 DOI: 10.1002/dvdy.590  0.421
2023 Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Sugimoto H, et al. Oncogenic Kras specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 T cells dependent manner. Biorxiv : the Preprint Server For Biology. PMID 36824971 DOI: 10.1101/2023.02.15.528757  0.525
2022 Haltom AR, Hassen WE, Hensel J, Kim J, Sugimoto H, Li B, McAndrews KM, Conner MR, Kirtley ML, Luo X, Xie B, Volpert OV, Olalekan S, Maltsev N, Basu A, ... LeBleu VS, et al. Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma. Extracellular Vesicle. 1. PMID 37503329 DOI: 10.1016/j.vesic.2022.100014  0.499
2022 Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Author Correction: Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. PMID 36198804 DOI: 10.1038/s41586-022-05062-9  0.482
2022 LeBleu VS. Plasticity Enables Cooperation among Heterogeneous Cancer Cell Populations to Support Metastatic Fitness. Cancer Research. 82: 1870-1871. PMID 35570704 DOI: 10.1158/0008-5472.CAN-22-0819  0.31
2022 McAndrews KM, Chen Y, Darpolor JK, Zheng X, Yang S, Carstens JL, Li B, Wang H, Miyake T, Correa de Sampaio P, Kirtley ML, Natale M, Wu CC, Sugimoto H, LeBleu VS, et al. Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL-6 Mediated Therapy Resistance in Pancreatic Cancer. Cancer Discovery. PMID 35348629 DOI: 10.1158/2159-8290.CD-20-1484  0.531
2022 McAndrews KM, Miyake T, Ehsanipour EA, Kelly PJ, Becker LM, McGrail DJ, Sugimoto H, LeBleu VS, Ge Y, Kalluri R. Dermal αSMA myofibroblasts orchestrate skin wound repair via β1 integrin and independent of type I collagen production. The Embo Journal. e109470. PMID 35212000 DOI: 10.15252/embj.2021109470  0.427
2022 El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, ... ... LeBleu VS, et al. Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2. Nature Communications. 13: 405. PMID 35058437 DOI: 10.1038/s41467-021-27893-2  0.439
2021 Zhou X, Kurywchak P, Wolf-Dennen K, Che SPY, Sulakhe D, D'Souza M, Xie B, Maltsev N, Gilliam TC, Wu CC, McAndrews KM, LeBleu VS, McConkey DJ, Volpert OV, Pretzsch SM, et al. Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer. Molecular Therapy. Methods & Clinical Development. 22: 360-376. PMID 34514028 DOI: 10.1016/j.omtm.2021.05.010  0.504
2021 McAndrews KM, Xiao F, Chronopoulos A, LeBleu VS, Kugeratski FG, Kalluri R. Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic Kras in pancreatic cancer. Life Science Alliance. 4. PMID 34282051 DOI: 10.26508/lsa.202000875  0.512
2021 McAndrews KM, Vázquez-Arreguín K, Kwak C, Sugimoto H, Zheng X, Li B, Kirtley ML, LeBleu VS, Kalluri R. αSMA fibroblasts suppress Lgr5 cancer stem cells and restrain colorectal cancer progression. Oncogene. PMID 34108617 DOI: 10.1038/s41388-021-01866-7  0.562
2021 Tang M, Chen Y, Li B, Sugimoto H, Yang S, Yang C, LeBleu VS, McAndrews KM, Kalluri R. Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21557. PMID 33855751 DOI: 10.1096/fj.202002777RR  0.471
2021 McAndrews KM, Che SPY, LeBleu VS, Kalluri R. Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances anti-tumor immunity. The Journal of Biological Chemistry. 100523. PMID 33711340 DOI: 10.1016/j.jbc.2021.100523  0.528
2021 Chen Y, Kim J, Yang S, Wang H, Wu CJ, Sugimoto H, LeBleu VS, Kalluri R. Type I collagen deletion in αSMA myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer. Cancer Cell. PMID 33667385 DOI: 10.1016/j.ccell.2021.02.007  0.567
2020 Hensel J, McAndrews KM, McGrail DJ, Dowlatshahi DP, LeBleu VS, Kalluri R. Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses. Scientific Reports. 10: 18377. PMID 33110184 DOI: 10.1038/s41598-020-75491-x  0.368
2020 McAndrews KM, Dowlatshahi DP, Dai J, Becker LM, Hensel J, Snowden LM, Leveille JM, Brunner MR, Holden K, Hopkins NS, Harris A, Kumpati JJ, Whitt MA, Lee JJ, Ostrosky-Zeichner L, ... ... LeBleu V, et al. Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications on COVID-19 immunity. Jci Insight. PMID 32796155 DOI: 10.1172/Jci.Insight.142386  0.396
2020 Lovisa S, Fletcher-Sananikone E, Sugimoto H, Hensel J, Lahiri S, Hertig A, Taduri G, Lawson E, Dewar R, Revuelta I, Kato N, Wu CJ, Bassett RL, Putluri N, Zeisberg M, ... ... LeBleu VS, et al. Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis. Science Signaling. 13. PMID 32518142 DOI: 10.1126/Scisignal.Aaz2597  0.543
2020 Becker LM, O'Connell JT, Vo AP, Cain MP, Tampe D, Bizarro L, Sugimoto H, McGow AK, Asara JM, Lovisa S, McAndrews KM, Zielinski R, Lorenzi PL, Zeisberg M, Raza S, ... LeBleu VS, et al. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer. Cell Reports. 31: 107701. PMID 32492417 DOI: 10.1016/J.Celrep.2020.107701  0.556
2020 LeBleu VS, Kalluri R. Exosomes as a Multicomponent Biomarker Platform in Cancer. Trends in Cancer. PMID 32307267 DOI: 10.1016/J.Trecan.2020.03.007  0.587
2020 LeBleu VS, Neilson EG. Origin and functional heterogeneity of fibroblasts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32037627 DOI: 10.1096/Fj.201903188R  0.337
2020 Kalluri R, LeBleu VS. The biology function and biomedical applications of exosomes. Science (New York, N.Y.). 367. PMID 32029601 DOI: 10.1126/science.aau6977  0.446
2020 Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, ... ... LeBleu VS, et al. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. PMID 31942075 DOI: 10.1038/S41586-019-1922-8  0.477
2019 McAndrews KM, LeBleu VS, Kalluri R. SIRT1 Regulates Lysosome Function and Exosome Secretion. Developmental Cell. 49: 302-303. PMID 31063745 DOI: 10.1016/J.Devcel.2019.04.024  0.555
2019 LeBleu VS, Kalluri R. Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy. Immunity. 50: 547-549. PMID 30893584 DOI: 10.1016/J.Immuni.2019.02.019  0.526
2018 Chen Y, Keskin D, Sugimoto H, Kanasaki K, Phillips PE, Bizarro L, Sharpe A, LeBleu VS, Kalluri R. Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis. Plos Biology. 16: e2005907. PMID 30592710 DOI: 10.1371/Journal.Pbio.2005907  0.531
2018 Parchem JG, Kanasaki K, Kanasaki M, Sugimoto H, Xie L, Hamano Y, Lee SB, Gattone VH, Parry S, Strauss JF, Garovic VD, McElrath TF, Lu KH, Sibai BM, LeBleu VS, et al. Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice. The Journal of Clinical Investigation. PMID 30179860 DOI: 10.1172/Jci99026  0.434
2018 Chen Y, LeBleu VS, Carstens JL, Sugimoto H, Zheng X, Malasi S, Saur D, Kalluri R. Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. Embo Molecular Medicine. PMID 30120146 DOI: 10.15252/emmm.201809085  0.531
2018 Eikesdal HP, Becker LM, Teng Y, Kizu A, Carstens JL, Kanasaki K, Sugimoto H, LeBleu VS, Kalluri R. BMP7 Signaling in TGFBR2-deficient Stromal Cells Provokes Epithelial Carcinogenesis. Molecular Cancer Research : McR. PMID 29934328 DOI: 10.1158/1541-7786.Mcr-18-0120  0.542
2018 LeBleu VS, Kalluri R. A peek into cancer-associated fibroblasts: origins, functions and translational impact. Disease Models & Mechanisms. 11. PMID 29686035 DOI: 10.1242/Dmm.029447  0.597
2018 Mendt M, Kamerkar S, Sugimoto H, McAndrews KM, Wu CC, Gagea M, Yang S, Blanko EVR, Peng Q, Ma X, Marszalek JR, Maitra A, Yee C, Rezvani K, Shpall E, ... LeBleu VS, et al. Generation and testing of clinical-grade exosomes for pancreatic cancer. Jci Insight. 3. PMID 29669940 DOI: 10.1172/Jci.Insight.99263  0.543
2017 Kamerkar S, LeBleu VS, Sugimoto H, Yang S, Ruivo CF, Melo SA, Lee JJ, Kalluri R. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. PMID 28607485 DOI: 10.1038/nature22341  0.531
2017 Carstens JL, Correa de Sampaio P, Yang D, Barua S, Wang H, Rao A, Allison JP, LeBleu VS, Kalluri R. Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer. Nature Communications. 8: 15095. PMID 28447602 DOI: 10.1038/Ncomms15095  0.475
2017 Kalluri R, LeBleu VS. Discovery of Double-Stranded Genomic DNA in Circulating Exosomes. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28424339 DOI: 10.1101/sqb.2016.81.030932  0.515
2017 Yang S, Che SP, Kurywchak P, Tavormina JL, Gansmo LB, Correa de Sampaio P, Tachezy M, Bockhorn M, Gebauer F, Haltom AR, Melo SA, LeBleu VS, Kalluri R. Detection of Mutant KRAS and TP53 DNA in Circulating Exosomes from Healthy Individuals and Patients with Pancreatic Cancer. Cancer Biology & Therapy. 0. PMID 28121262 DOI: 10.1080/15384047.2017.1281499  0.446
2016 Kim J, de Sampaio PC, Lundy DM, Peng Q, Evans KW, Sugimoto H, Gagea M, Kienast Y, do Amaral NS, Rocha RM, Eikesdal HP, Lønning PE, Meric-Bernstam F, LeBleu VS. Heterogeneous perivascular cell coverage affects breast cancer metastasis and response to chemotherapy. Jci Insight. 1: e90733. PMID 28018977 DOI: 10.1172/Jci.Insight.90733  0.416
2016 Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. PMID 27089513 DOI: 10.1038/Nm.4082  0.556
2015 Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... ... LeBleu VS, et al. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 28: 831-833. PMID 28843279 DOI: 10.1016/J.Ccell.2015.11.002  0.551
2015 Cleland TP, Schroeter ER, Zamdborg L, Zheng W, Lee JE, Tran JC, Bern M, Duncan MB, Lebleu VS, Ahlf DR, Thomas PM, Kalluri R, Kelleher NL, Schweitzer MH. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. Journal of Proteome Research. PMID 26595531 DOI: 10.1021/Acs.Jproteome.5B00675  0.472
2015 Zheng X, Carstens JL, Kim J, Scheible M, Kaye J, Sugimoto H, Wu CC, LeBleu VS, Kalluri R. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature. PMID 26560028 DOI: 10.1038/Nature16064  0.6
2015 Lovisa S, LeBleu VS, Tampe B, Sugimoto H, Vadnagara K, Carstens JL, Wu CC, Hagos Y, Burckhardt BC, Pentcheva-Hoang T, Nischal H, Allison JP, Zeisberg M, Kalluri R. Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis. Nature Medicine. PMID 26236991 DOI: 10.1038/Nm.3902  0.545
2015 Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. PMID 26106858 DOI: 10.1038/Nature14581  0.518
2015 Keskin D, Kim J, Cooke VG, Wu CC, Sugimoto H, Gu C, De Palma M, Kalluri R, LeBleu VS. Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2. Cell Reports. 10: 1066-81. PMID 25704811 DOI: 10.1016/j.celrep.2015.01.035  0.506
2014 LeBleu VS, O'Connell JT, Gonzalez Herrera KN, Wikman H, Pantel K, Haigis MC, de Carvalho FM, Damascena A, Domingos Chinen LT, Rocha RM, Asara JM, Kalluri R. PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis. Nature Cell Biology. 16: 992-1003, 1-15. PMID 25241037 DOI: 10.1038/Ncb3039  0.588
2014 Zeisberg M, Tampe B, LeBleu V, Tampe D, Zeisberg EM, Kalluri R. Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure. The American Journal of Pathology. 184: 2687-98. PMID 25111226 DOI: 10.1016/j.ajpath.2014.06.014  0.462
2014 Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... ... LeBleu VS, et al. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 25: 719-34. PMID 24856586 DOI: 10.1016/J.Ccr.2014.04.005  0.558
2014 Tampe B, Tampe D, Müller CA, Sugimoto H, LeBleu V, Xu X, Müller GA, Zeisberg EM, Kalluri R, Zeisberg M. Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis. Journal of the American Society of Nephrology : Jasn. 25: 905-12. PMID 24480825 DOI: 10.1681/ASN.2013070723  0.481
2014 LeBleu VS, O'Connell JT, Herrera KNG, Wikman H, Pantel K, Haigis MC, de Carvalho FM, Damascena A, Chinen LTD, Rocha RM, Asara JM, Kalluri R. Erratum: Corrigendum: PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis Nature Cell Biology. 16: 1125-1125. DOI: 10.1038/Ncb3056  0.53
2013 Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3. Nature Medicine. 19: 810-1. PMID 23836214 DOI: 10.1038/Nm.3081  0.453
2013 LeBleu VS, Taduri G, O'Connell J, Teng Y, Cooke VG, Woda C, Sugimoto H, Kalluri R. Origin and function of myofibroblasts in kidney fibrosis. Nature Medicine. 19: 1047-53. PMID 23817022 DOI: 10.1038/Nm.3218  0.558
2013 LeBleu VS, Teng Y, O'Connell JT, Charytan D, Müller GA, Müller CA, Sugimoto H, Kalluri R. Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. Nature Medicine. 19: 227-31. PMID 23353556 DOI: 10.1038/Nm.2989  0.541
2013 Borges FT, Melo SA, Özdemir BC, Kato N, Revuelta I, Miller CA, Gattone VH, LeBleu VS, Kalluri R. TGF-β1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. Journal of the American Society of Nephrology : Jasn. 24: 385-92. PMID 23274427 DOI: 10.1681/Asn.2012101031  0.539
2012 Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nature Medicine. 18: 396-404. PMID 22306733 DOI: 10.1038/Nm.2629  0.541
2012 Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y, Duncan MB, Xie L, Maeda G, Vong S, Sugimoto H, Rocha RM, Damascena A, Brentani RR, Kalluri R. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 21: 66-81. PMID 22264789 DOI: 10.1016/J.Ccr.2011.11.024  0.701
2011 LeBleu VS, Kalluri R. Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis. Kidney International. 80: 1119-21. PMID 22083636 DOI: 10.1038/ki.2011.300  0.453
2011 O'Connell JT, Sugimoto H, Cooke VG, MacDonald BA, Mehta AI, LeBleu VS, Dewar R, Rocha RM, Brentani RR, Resnick MB, Neilson EG, Zeisberg M, Kalluri R. VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proceedings of the National Academy of Sciences of the United States of America. 108: 16002-7. PMID 21911392 DOI: 10.1073/Pnas.1109493108  0.586
2011 De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Maertens O, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, et al. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell. 20: 400-13. PMID 21907929 DOI: 10.1016/J.Ccr.2011.08.014  0.536
2010 LeBleu V, Sund M, Sugimoto H, Birrane G, Kanasaki K, Finan E, Miller CA, Gattone VH, McLaughlin H, Shield CF, Kalluri R. Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly. The Journal of Biological Chemistry. 285: 41874-85. PMID 20847057 DOI: 10.1074/Jbc.M110.149534  0.473
2009 LeBleu V, Sugimoto H, Mundel TM, Gerami-Naini B, Finan E, Miller CA, Gattone VH, Lu L, Shield CF, Folkman J, Kalluri R. Stem cell therapies benefit Alport syndrome. Journal of the American Society of Nephrology : Jasn. 20: 2359-70. PMID 19833902 DOI: 10.1681/Asn.2009010123  0.542
2009 Schweitzer MH, Zheng W, Organ CL, Avci R, Suo Z, Freimark LM, Lebleu VS, Duncan MB, Vander Heiden MG, Neveu JM, Lane WS, Cottrell JS, Horner JR, Cantley LC, Kalluri R, et al. Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis. Science (New York, N.Y.). 324: 626-31. PMID 19407199 DOI: 10.1126/Science.1165069  0.481
2009 Bleicher M, LeBleu V, Doyle A, Kearns J, Bloom R, Tomaszewski J, Kalluri R, Kamoun M. 263-P: Acute AMR associated with anti-GBM antibodies in a kidney transplant recipient with Alport's syndrome Human Immunology. 70: S144. DOI: 10.1016/J.Humimm.2009.09.296  0.456
2008 LeBleu VS, Kalluri R. Stem cell-based therapy for glomerular diseases: an evolving concept. Journal of the American Society of Nephrology : Jasn. 19: 1621-3. PMID 18701605 DOI: 10.1681/Asn.2008070735  0.514
2008 Lebleu VS, Sugimoto H, Miller CA, Gattone VH, Kalluri R. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 284-92. PMID 18180701 DOI: 10.1038/Labinvest.3700715  0.532
2008 Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, Lebleu VS, Gattone VH, Kalluri R. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Developmental Biology. 313: 584-93. PMID 18082680 DOI: 10.1016/J.Ydbio.2007.10.047  0.504
2007 LeBleu VS, Macdonald B, Kalluri R. Structure and function of basement membranes. Experimental Biology and Medicine (Maywood, N.J.). 232: 1121-9. PMID 17895520 DOI: 10.3181/0703-Mr-72  0.519
2007 Sugimoto H, Yang C, LeBleu VS, Soubasakos MA, Giraldo M, Zeisberg M, Kalluri R. BMP-7 functions as a novel hormone to facilitate liver regeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 256-64. PMID 17116741 DOI: 10.1096/Fj.06-6837Com  0.489
Show low-probability matches.