Year |
Citation |
Score |
2020 |
Chakraborty AA. Coalescing Lessons from Oxygen Sensing, Tumor Metabolism, and Epigenetics to Target VHL loss in Kidney Cancer. Seminars in Cancer Biology. PMID 32209418 DOI: 10.1016/j.semcancer.2020.03.012 |
0.302 |
|
2019 |
Oser MG, Sabet AH, Gao W, Chakraborty AA, Schinzel AC, Jennings RB, Fonseca R, Bonal DM, Booker MA, Flaifel A, Novak JS, Christensen CL, Zhang H, Herbert ZT, Tolstorukov MY, et al. The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis. Genes & Development. PMID 31727771 DOI: 10.1101/Gad.328336.119 |
0.441 |
|
2019 |
Sethi N, Kikuchi O, McFarland J, Zhang Y, Chung M, Kafker N, Islam M, Lampson B, Chakraborty A, Kaelin WG, Bass AJ. Mutant p53 induces a hypoxia transcriptional program in gastric and esophageal adenocarcinoma. Jci Insight. 4. PMID 31391338 DOI: 10.1172/Jci.Insight.128439 |
0.421 |
|
2018 |
Oser MG, Fonseca R, Chakraborty AA, Brough R, Spektor A, Jennings RB, Flaifel A, Novak JS, Gulati A, Buss E, Younger ST, McBrayer SK, Cowley GS, Bonal DM, Nguyen QD, et al. Cells Lacking the RB1 Tumor Suppressor Gene are Hyperdependent on Aurora B Kinase for Survival. Cancer Discovery. PMID 30373918 DOI: 10.1158/2159-8290.Cd-18-0389 |
0.349 |
|
2018 |
McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, et al. Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell. PMID 30220459 DOI: 10.1016/J.Cell.2018.08.038 |
0.314 |
|
2017 |
Chakraborty AA, Nakamura E, Qi J, Creech A, Jaffe JD, Paulk J, Novak JS, Nagulapalli K, McBrayer SK, Cowley GS, Pineda J, Song J, Wang YE, Carr SA, Root DE, et al. HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase. Science Translational Medicine. 9. PMID 28701475 DOI: 10.1126/Scitranslmed.Aal5272 |
0.474 |
|
2016 |
Cho H, Du X, Rizzi JP, Liberzon E, Chakraborty AA, Gao W, Carvo I, Signoretti S, Bruick R, Josey JA, Wallace EM, Kaelin WG. On-Target Efficacy of a HIF2α Antagonist in Preclinical Kidney Cancer Models. Nature. PMID 27595393 DOI: 10.1038/Nature19795 |
0.382 |
|
2016 |
Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang J, Zhang L, Yuan M, Novak J, Cheng JQ, Toker A, Signoretti S, Zhang Q, et al. pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. Science (New York, N.Y.). 353: 929-32. PMID 27563096 DOI: 10.1126/Science.Aad5755 |
0.378 |
|
2015 |
Chakraborty AA, Tansey WP. Do changes in the c-MYC coding sequence contribute to tumorigenesis? Molecular & Cellular Oncology. 2: e965631. PMID 27308414 DOI: 10.4161/23723548.2014.965631 |
0.575 |
|
2015 |
Chakraborty AA, Scuoppo C, Dey S, Thomas LR, Lorey SL, Lowe SW, Tansey WP. A common functional consequence of tumor-derived mutations within c-MYC. Oncogene. 34: 2406-9. PMID 24998853 DOI: 10.1038/Onc.2014.186 |
0.622 |
|
2014 |
Zheng X, Zhai B, Koivunen P, Shin SJ, Lu G, Liu J, Geisen C, Chakraborty AA, Moslehi JJ, Smalley DM, Wei X, Chen X, Chen Z, Beres JM, Zhang J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes & Development. 28: 1429-44. PMID 24990963 DOI: 10.1101/Gad.242131.114 |
0.411 |
|
2009 |
Chakraborty AA, Tansey WP. Inference of cell cycle-dependent proteolysis by laser scanning cytometry. Experimental Cell Research. 315: 1772-8. PMID 19331831 DOI: 10.1016/J.Yexcr.2009.01.011 |
0.549 |
|
2009 |
Chakraborty AA, Tansey WP. Adenoviral E1A function through Myc. Cancer Research. 69: 6-9. PMID 19117980 DOI: 10.1158/0008-5472.Can-08-3026 |
0.704 |
|
2008 |
Tworkowski KA, Chakraborty AA, Samuelson AV, Seger YR, Narita M, Hannon GJ, Lowe SW, Tansey WP. Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc Proceedings of the National Academy of Sciences of the United States of America. 105: 6103-6108. PMID 18413597 DOI: 10.1073/Pnas.0802095105 |
0.452 |
|
2004 |
Gohil K, Chakraborty AA. Applications of microarray and bioinformatics tools to dissect molecular responses of the central nervous system to antioxidant micronutrients. Nutrition (Burbank, Los Angeles County, Calif.). 20: 50-5. PMID 14698014 DOI: 10.1016/J.Nut.2003.09.009 |
0.316 |
|
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