Damian C. Genetos, Ph.D. - Publications

Affiliations: 
2005 Pennsylvania State University, State College, PA, United States 
Area:
Physiology Biology, Cell Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Harvestine JN, Gonzalez-Fernandez T, Sebastian A, Hum NR, Genetos DC, Loots GG, Leach JK. Osteogenic preconditioning in perfusion bioreactors improves vascularization and bone formation by human bone marrow aspirates. Science Advances. 6: eaay2387. PMID 32095526 DOI: 10.1126/Sciadv.Aay2387  0.441
2019 Pusceddu MM, Stokes PJ, Wong A, Gareau MG, Genetos DC. Sexually-dimorphic influence of neonatal antibiotics on bone. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 31228216 DOI: 10.1002/Jor.24396  0.331
2019 Yellowley CE, Genetos DC. Hypoxia Signaling in the Skeleton: Implications for Bone Health. Current Osteoporosis Reports. PMID 30725321 DOI: 10.1007/S11914-019-00500-6  0.392
2018 Loots GG, Robling AG, Chang JC, Murugesh DK, Bajwa J, Carlisle C, Manilay JO, Wong A, Yellowley CE, Genetos DC. Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects. Bone. PMID 30172741 DOI: 10.1016/J.Bone.2018.08.022  0.439
2017 Donahue HJ, Qu RW, Genetos DC. Joint diseases: from connexins to gap junctions. Nature Reviews. Rheumatology. 14: 42-51. PMID 29255213 DOI: 10.1038/Nrrheum.2017.204  0.602
2017 Heffner MA, Genetos DC, Christiansen BA. Bone adaptation to mechanical loading in a mouse model of reduced peripheral sensory nerve function. Plos One. 12: e0187354. PMID 29088267 DOI: 10.1371/Journal.Pone.0187354  0.405
2017 Murphy KC, Hung BP, Browne-Bourne S, Zhou D, Yeung J, Genetos DC, Leach JK. Measurement of oxygen tension within mesenchymal stem cell spheroids. Journal of the Royal Society, Interface. 14. PMID 28179546 DOI: 10.1098/Rsif.2016.0851  0.336
2016 Robling AG, Kang KS, Bullock WA, Foster WH, Murugesh D, Loots GG, Genetos DC. Sost, independent of the non-coding enhancer ECR5, is required for bone mechanoadaptation. Bone. PMID 27601226 DOI: 10.1016/J.Bone.2016.09.001  0.44
2015 Wong A, Loots GG, Yellowley CE, Dosé AC, Genetos DC. Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells. Bone. 81: 97-103. PMID 26151122 DOI: 10.1016/J.Bone.2015.07.002  0.411
2015 Khorasani MS, Diko S, Hsia AW, Anderson MJ, Genetos DC, Haudenschild DR, Christiansen BA. Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice. Arthritis Research & Therapy. 17: 30. PMID 25888819 DOI: 10.1186/S13075-015-0546-0  0.315
2014 Genetos DC, Wong A, Weber TJ, Karin NJ, Yellowley CE. Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells. Plos One. 9: e107482. PMID 25222280 DOI: 10.1371/Journal.Pone.0107482  0.431
2014 Chahine NO, Collette NM, Thomas CB, Genetos DC, Loots GG. Nanocomposite scaffold for chondrocyte growth and cartilage tissue engineering: effects of carbon nanotube surface functionalization. Tissue Engineering. Part A. 20: 2305-15. PMID 24593020 DOI: 10.1089/Ten.Tea.2013.0328  0.312
2014 Binder BY, Genetos DC, Leach JK. Lysophosphatidic acid protects human mesenchymal stromal cells from differentiation-dependent vulnerability to apoptosis. Tissue Engineering. Part A. 20: 1156-64. PMID 24131310 DOI: 10.1089/Ten.Tea.2013.0487  0.366
2013 Donahue HJ, Genetos DC. Genomic approaches in breast cancer research. Briefings in Functional Genomics. 12: 391-6. PMID 23788797 DOI: 10.1093/Bfgp/Elt019  0.498
2012 Morales-Hernandez DG, Genetos DC, Working DM, Murphy KC, Leach JK. Ceramic identity contributes to mechanical properties and osteoblast behavior on macroporous composite scaffolds. Journal of Functional Biomaterials. 3: 382-97. PMID 24955539 DOI: 10.3390/Jfb3020382  0.373
2012 Collette NM, Genetos DC, Economides AN, Xie L, Shahnazari M, Yao W, Lane NE, Harland RM, Loots GG. Targeted deletion of Sost distal enhancer increases bone formation and bone mass. Proceedings of the National Academy of Sciences of the United States of America. 109: 14092-7. PMID 22886088 DOI: 10.1073/Pnas.1207188109  0.428
2012 Genetos DC, Zhou Z, Li Z, Donahue HJ. Age-related changes in gap junctional intercellular communication in osteoblastic cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1979-84. PMID 22696456 DOI: 10.1002/Jor.22172  0.586
2012 Toupadakis CA, Wong A, Genetos DC, Chung DJ, Murugesh D, Anderson MJ, Loots GG, Christiansen BA, Kapatkin AS, Yellowley CE. Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1853-9. PMID 22592891 DOI: 10.1002/Jor.22145  0.396
2012 Hoch AI, Binder BY, Genetos DC, Leach JK. Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells. Plos One. 7: e35579. PMID 22536411 DOI: 10.1371/Journal.Pone.0035579  0.427
2012 Loots GG, Keller H, Leupin O, Murugesh D, Collette NM, Genetos DC. TGF-β regulates sclerostin expression via the ECR5 enhancer. Bone. 50: 663-9. PMID 22155511 DOI: 10.1016/J.Bone.2011.11.016  0.33
2012 Watari S, Hayashi K, Wood JA, Russell P, Nealey PF, Murphy CJ, Genetos DC. Modulation of osteogenic differentiation in hMSCs cells by submicron topographically-patterned ridges and grooves. Biomaterials. 33: 128-36. PMID 21982295 DOI: 10.1016/J.Biomaterials.2011.09.058  0.345
2011 Morgan JM, Wong A, Yellowley CE, Genetos DC. Regulation of tenascin expression in bone. Journal of Cellular Biochemistry. 112: 3354-63. PMID 21751239 DOI: 10.1002/Jcb.23265  0.458
2011 Davis HE, Case EM, Miller SL, Genetos DC, Leach JK. Osteogenic response to BMP-2 of hMSCs grown on apatite-coated scaffolds. Biotechnology and Bioengineering. 108: 2727-35. PMID 21656707 DOI: 10.1002/Bit.23227  0.476
2011 Raheja LF, Genetos DC, Wong A, Yellowley CE. Hypoxic regulation of mesenchymal stem cell migration: the role of RhoA and HIF-1α. Cell Biology International. 35: 981-9. PMID 21574962 DOI: 10.1042/Cbi20100733  0.366
2011 Morgan JM, Wong A, Genetos DC, Yellowley CE. Src is sufficient, but not necessary, for osteopontin induction in osteoblasts. Biorheology. 48: 65-74. PMID 21515937 DOI: 10.3233/Bir-2011-0582  0.471
2011 Genetos DC, Yellowley CE, Loots GG. Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression. Plos One. 6: e17772. PMID 21436889 DOI: 10.1371/Journal.Pone.0017772  0.442
2011 Genetos DC, Karin NJ, Geist DJ, Donahue HJ, Duncan RL. Purinergic signaling is required for fluid shear stress-induced NF-κB translocation in osteoblasts. Experimental Cell Research. 317: 737-44. PMID 21237152 DOI: 10.1016/J.Yexcr.2011.01.007  0.557
2010 Toupadakis CA, Wong A, Genetos DC, Cheung WK, Borjesson DL, Ferraro GL, Galuppo LD, Leach JK, Owens SD, Yellowley CE. Comparison of the osteogenic potential of equine mesenchymal stem cells from bone marrow, adipose tissue, umbilical cord blood, and umbilical cord tissue. American Journal of Veterinary Research. 71: 1237-45. PMID 20919913 DOI: 10.2460/Ajvr.71.10.1237  0.362
2010 Genetos DC, Wong A, Watari S, Yellowley CE. Hypoxia increases Annexin A2 expression in osteoblastic cells via VEGF and ERK. Bone. 47: 1013-9. PMID 20817051 DOI: 10.1016/J.Bone.2010.08.024  0.356
2010 Schaff UY, Trott KA, Chase S, Tam K, Johns JL, Carlyon JA, Genetos DC, Walker NJ, Simon SI, Borjesson DL. Neutrophils exposed to A. phagocytophilum under shear stress fail to fully activate, polarize, and transmigrate across inflamed endothelium. American Journal of Physiology. Cell Physiology. 299: C87-96. PMID 20392928 DOI: 10.1152/Ajpcell.00165.2009  0.35
2010 Collette NM, Genetos DC, Murugesh D, Harland RM, Loots GG. Genetic evidence that SOST inhibits WNT signaling in the limb. Developmental Biology. 342: 169-79. PMID 20359476 DOI: 10.1016/J.Ydbio.2010.03.021  0.372
2010 Genetos DC, Toupadakis CA, Raheja LF, Wong A, Papanicolaou SE, Fyhrie DP, Loots GG, Yellowley CE. Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts. Journal of Cellular Biochemistry. 110: 457-67. PMID 20336693 DOI: 10.1002/Jcb.22559  0.411
2010 He J, Genetos DC, Yellowley CE, Leach JK. Oxygen tension differentially influences osteogenic differentiation of human adipose stem cells in 2D and 3D cultures. Journal of Cellular Biochemistry. 110: 87-96. PMID 20213746 DOI: 10.1002/Jcb.22514  0.331
2010 Genetos DC, Rao RR, Vidal MA. Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha. Cell and Tissue Research. 340: 81-9. PMID 20165885 DOI: 10.1007/S00441-010-0929-0  0.436
2010 Genetos DC, Cheung WK, Decaris ML, Leach JK. Oxygen tension modulates neurite outgrowth in PC12 cells through a mechanism involving HIF and VEGF. Journal of Molecular Neuroscience : Mn. 40: 360-6. PMID 20107925 DOI: 10.1007/S12031-009-9326-0  0.318
2010 Raheja LF, Genetos DC, Yellowley CE. The effect of oxygen tension on the long-term osteogenic differentiation and MMP/TIMP expression of human mesenchymal stem cells. Cells, Tissues, Organs. 191: 175-84. PMID 19690399 DOI: 10.1159/000235679  0.346
2010 He J, Genetos DC, Leach JK. Osteogenesis and trophic factor secretion are influenced by the composition of hydroxyapatite/poly(lactide-co-glycolide) composite scaffolds. Tissue Engineering. Part A. 16: 127-37. PMID 19642853 DOI: 10.1089/Ten.Tea.2009.0255  0.364
2010 Lee CM, Genetos DC, Wong A, Yellowley CE. Prostaglandin expression profile in hypoxic osteoblastic cells. Journal of Bone and Mineral Metabolism. 28: 8-16. PMID 19471853 DOI: 10.1007/S00774-009-0096-0  0.452
2009 Papanicolaou SE, Phipps RJ, Fyhrie DP, Genetos DC. Modulation of sclerostin expression by mechanical loading and bone morphogenetic proteins in osteogenic cells. Biorheology. 46: 389-99. PMID 19940355 DOI: 10.3233/Bir-2009-0550  0.461
2009 Genetos DC, Lee CM, Wong A, Yellowley CE. HIF-1alpha regulates hypoxia-induced EP1 expression in osteoblastic cells. Journal of Cellular Biochemistry. 107: 233-9. PMID 19277991 DOI: 10.1002/Jcb.22119  0.372
2008 Liu D, Genetos DC, Shao Y, Geist DJ, Li J, Ke HZ, Turner CH, Duncan RL. Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts. Bone. 42: 644-52. PMID 18291742 DOI: 10.1016/J.Bone.2007.09.058  0.385
2008 Raheja LF, Genetos DC, Yellowley CE. Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway. Biochemical and Biophysical Research Communications. 366: 1061-6. PMID 18155656 DOI: 10.1016/J.Bbrc.2007.12.076  0.347
2007 Waters KM, Tan R, Genetos DC, Verma S, Yellowley CE, Karin NJ. DNA microarray analysis reveals a role for lysophosphatidic acid in the regulation of anti-inflammatory genes in MC3T3-E1 cells Bone. 41: 833-841. PMID 17719864 DOI: 10.1016/J.Bone.2007.06.029  0.427
2007 Lee CM, Genetos DC, You Z, Yellowley CE. Hypoxia regulates PGE(2) release and EP1 receptor expression in osteoblastic cells. Journal of Cellular Physiology. 212: 182-8. PMID 17370287 DOI: 10.1002/Jcp.21017  0.403
2007 Genetos DC, Kephart CJ, Zhang Y, Yellowley CE, Donahue HJ. Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes. Journal of Cellular Physiology. 212: 207-14. PMID 17301958 DOI: 10.1002/Jcp.21021  0.631
2006 Riddle RC, Taylor AF, Genetos DC, Donahue HJ. MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation. American Journal of Physiology. Cell Physiology. 290: C776-84. PMID 16267109 DOI: 10.1152/Ajpcell.00082.2005  0.696
2005 Genetos DC, Geist DJ, Liu D, Donahue HJ, Duncan RL. Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 41-9. PMID 15619668 DOI: 10.1359/Jbmr.041009  0.562
2005 Genetos DC, Donahue HJ. Intercellular communication and mechanotransduction in bone Current Opinion in Orthopaedics. 16: 311-315. DOI: 10.1097/01.Bco.0000178256.55565.Ee  0.573
2004 Haut Donahue TL, Genetos DC, Jacobs CR, Donahue HJ, Yellowley CE. Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells Bone. 35: 656-663. PMID 15336601 DOI: 10.1016/J.Bone.2004.04.025  0.654
2003 Chen NX, Geist DJ, Genetos DC, Pavalko FM, Duncan RL. Fluid shear-induced NFkappaB translocation in osteoblasts is mediated by intracellular calcium release. Bone. 33: 399-410. PMID 13678782 DOI: 10.1016/S8756-3282(03)00159-5  0.418
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