| Year |
Citation |
Score |
| 2023 |
Polychronidou M, Hou J, Babu MM, Liberali P, Amit I, Deplancke B, Lahav G, Itzkovitz S, Mann M, Saez-Rodriguez J, Theis F, Eils R. Single-cell biology: what does the future hold? Molecular Systems Biology. e11799. PMID 37318792 DOI: 10.15252/msb.202311799 |
0.33 |
|
| 2023 |
Chen JY, Hug C, Reyes J, Tian C, Gerosa L, Fröhlich F, Ponsioen B, Snippert HJG, Spencer SL, Jambhekar A, Sorger PK, Lahav G. Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction. Cell Reports. 42: 112252. PMID 36920903 DOI: 10.1016/j.celrep.2023.112252 |
0.311 |
|
| 2022 |
Jiménez A, Lu D, Kalocsay M, Berberich MJ, Balbi P, Jambhekar A, Lahav G. Time-series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations. Molecular Systems Biology. 18: e10588. PMID 35285572 DOI: 10.15252/msb.202110588 |
0.421 |
|
| 2021 |
Nandagopal N, Jambhekar A, Lahav G. Preparing macrophages for the future. Science (New York, N.Y.). 372: 1263-1264. PMID 34140370 DOI: 10.1126/science.abj2040 |
0.646 |
|
| 2021 |
Stewart-Ornstein J, Iwamoto Y, Miller MA, Prytyskach MA, Ferretti S, Holzer P, Kallen J, Furet P, Jambhekar A, Forrester WC, Weissleder R, Lahav G. p53 dynamics vary between tissues and are linked with radiation sensitivity. Nature Communications. 12: 898. PMID 33563973 DOI: 10.1038/s41467-021-21145-z |
0.385 |
|
| 2020 |
Tsabar M, Mock CS, Venkatachalam V, Reyes J, Karhohs KW, Oliver TG, Regev A, Jambhekar A, Lahav G. A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest. Cell Reports. 33: 108392. PMID 33176156 DOI: 10.1016/j.celrep.2020.108392 |
0.509 |
|
| 2020 |
Tsabar M, Mock CS, Venkatachalam V, Reyes J, Karhohs KW, Oliver TG, Regev A, Jambhekar A, Lahav G. A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest. Cell Reports. 32: 107995. PMID 32755587 DOI: 10.1016/J.Celrep.2020.107995 |
0.58 |
|
| 2020 |
Hafner A, Reyes J, Stewart-Ornstein J, Tsabar M, Jambhekar A, Lahav G. Quantifying the Central Dogma in the p53 Pathway in Live Single Cells. Cell Systems. PMID 32533938 DOI: 10.1016/J.Cels.2020.05.001 |
0.524 |
|
| 2020 |
Hafner A, Kublo L, Tsabar M, Lahav G, Stewart-Ornstein J. Identification of universal and cell-type specific p53 DNA binding. Bmc Molecular and Cell Biology. 21: 5. PMID 32070277 DOI: 10.1186/s12860-020-00251-8 |
0.391 |
|
| 2020 |
Granada AE, Jiménez A, Stewart-Ornstein J, Blüthgen N, Reber S, Jambhekar A, Lahav G. The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy. Molecular Biology of the Cell. mbcE19090515. PMID 32049575 DOI: 10.1091/Mbc.E19-09-0515 |
0.471 |
|
| 2019 |
Heltberg ML, Chen SH, Jiménez A, Jambhekar A, Jensen MH, Lahav G. Inferring Leading Interactions in the p53/Mdm2/Mdmx Circuit through Live-Cell Imaging and Modeling. Cell Systems. PMID 31812692 DOI: 10.1016/J.Cels.2019.10.010 |
0.569 |
|
| 2019 |
Ardon-Dryer K, Mock C, Reyes J, Lahav G. The effect of dust storm particles on single human lung cancer cells. Environmental Research. 108891. PMID 31740036 DOI: 10.1016/J.Envres.2019.108891 |
0.365 |
|
| 2019 |
Reyes J, Chen JY, Stewart-Ornstein J, Karhohs KW, Mock CS, Lahav G. Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest. Molecular Cell. 73: 1306. PMID 30901565 DOI: 10.1016/j.molcel.2019.02.035 |
0.468 |
|
| 2019 |
Hafner A, Bulyk ML, Jambhekar A, Lahav G. The multiple mechanisms that regulate p53 activity and cell fate. Nature Reviews. Molecular Cell Biology. PMID 30824861 DOI: 10.1038/S41580-019-0110-X |
0.534 |
|
| 2019 |
Lu D, Holton K, Hafner A, DeHart C, Sikora J, Zhou H, Jambhekar A, Kelleher N, Gunawardena J, Lahav G. Abstract LB-101: Combined p53 dynamics and post-translational modifications determine subsequent protein expression and cell fate Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-Lb-101 |
0.528 |
|
| 2018 |
Gilad T, Reyes J, Chen JY, Lahav G, Raviv TR. Fully Unsupervised Symmetry-Based Mitosis Detection in Time-Lapse Cell Microscopy. Bioinformatics (Oxford, England). PMID 30590471 DOI: 10.1093/Bioinformatics/Bty1034 |
0.41 |
|
| 2018 |
Chakrabarti S, Paek AL, Reyes J, Lasick KA, Lahav G, Michor F. Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages. Nature Communications. 9: 5372. PMID 30560953 DOI: 10.1038/S41467-018-07788-5 |
0.46 |
|
| 2018 |
Reyes J, Chen JY, Stewart-Ornstein J, Karhohs KW, Mock CS, Lahav G. Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest. Molecular Cell. PMID 30057196 DOI: 10.1016/J.Molcel.2018.06.031 |
0.59 |
|
| 2018 |
Arbelle A, Reyes J, Chen JY, Lahav G, Riklin Raviv T. A probabilistic approach to joint cell tracking and segmentation in high-throughput microscopy videos. Medical Image Analysis. 47: 140-152. PMID 29747154 DOI: 10.1016/J.Media.2018.04.006 |
0.415 |
|
| 2018 |
Endress JE, Harris IS, Stewart-Ornstein J, Lahav G, Brugge JS. Abstract 1851: Combined inhibition of PARP and the unfolded protein response synergistically reduces viability in BRCA1-mutant breast cancer cells Cancer Research. 78: 1851-1851. DOI: 10.1158/1538-7445.Am2018-1851 |
0.362 |
|
| 2017 |
Reyes J, Lahav G. Leveraging and coping with uncertainty in the response of individual cells to therapy. Current Opinion in Biotechnology. 51: 109-115. PMID 29288931 DOI: 10.1016/J.Copbio.2017.12.007 |
0.391 |
|
| 2017 |
Stewart-Ornstein J, Cheng HWJ, Lahav G. Conservation and Divergence of p53 Oscillation Dynamics across Species. Cell Systems. PMID 29055670 DOI: 10.1016/J.Cels.2017.09.012 |
0.568 |
|
| 2017 |
Hafner A, Stewart-Ornstein J, Purvis JE, Forrester WC, Bulyk ML, Lahav G. p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics. Nature Structural & Molecular Biology. PMID 28825732 DOI: 10.1038/Nsmb.3452 |
0.475 |
|
| 2017 |
Tsabar M, Lahav G. The Single-Cell Yin and Yang of Live Imaging and Transcriptomics. Cell Systems. 4: 375-377. PMID 28448797 DOI: 10.1016/J.Cels.2017.04.001 |
0.417 |
|
| 2017 |
Stewart-Ornstein J, Lahav G. p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM. Science Signaling. 10. PMID 28442631 DOI: 10.1126/Scisignal.Aah6671 |
0.608 |
|
| 2016 |
Drayman N, Ben-Nun-Shaul O, Butin-Israeli V, Srivastava R, Rubinstein AM, Mock CS, Elyada E, Ben-Neriah Y, Lahav G, Oppenheim A. p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression. Oncotarget. PMID 27462916 DOI: 10.18632/Oncotarget.10769 |
0.432 |
|
| 2016 |
Paek AL, Liu JC, Loewer A, Forrester WC, Lahav G. Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing. Cell. PMID 27062928 DOI: 10.1016/J.Cell.2016.03.025 |
0.561 |
|
| 2016 |
Chen SH, Forrester W, Lahav G. Schedule-dependent interaction between anticancer treatments. Science (New York, N.Y.). 351: 1204-8. PMID 26965628 DOI: 10.1126/Science.Aac5610 |
0.537 |
|
| 2016 |
Stewart-Ornstein J, Lahav G. Dynamics of CDKN1A in Single Cells Defined by an Endogenous Fluorescent Tagging Toolkit. Cell Reports. PMID 26876176 DOI: 10.1016/J.Celrep.2016.01.045 |
0.498 |
|
| 2015 |
Lande-Diner L, Stewart-Ornstein J, Weitz CJ, Lahav G. Single-cell analysis of circadian dynamics in tissue explants. Molecular Biology of the Cell. 26: 3940-5. PMID 26269583 DOI: 10.1091/Mbc.E15-06-0403 |
0.445 |
|
| 2014 |
Gaglia G, Lahav G. Constant rate of p53 tetramerization in response to DNA damage controls the p53 response. Molecular Systems Biology. 10: 753. PMID 25344068 DOI: 10.15252/Msb.20145168 |
0.797 |
|
| 2014 |
Liu JC, Lerou PH, Lahav G. Stem cells: balancing resistance and sensitivity to DNA damage. Trends in Cell Biology. 24: 268-74. PMID 24721782 DOI: 10.1016/J.Tcb.2014.03.002 |
0.419 |
|
| 2013 |
Loewer A, Karanam K, Mock C, Lahav G. The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold. Bmc Biology. 11: 114. PMID 24252182 DOI: 10.1186/1741-7007-11-114 |
0.586 |
|
| 2013 |
Gaglia G, Guan Y, Shah JV, Lahav G. Activation and control of p53 tetramerization in individual living cells Proceedings of the National Academy of Sciences of the United States of America. 110: 15497-15501. PMID 24006363 DOI: 10.1073/Pnas.1311126110 |
0.81 |
|
| 2013 |
Liu JC, Guan X, Ryan JA, Rivera AG, Mock C, Agrawal V, Agarwal V, Letai A, Lerou PH, Lahav G. High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis. Cell Stem Cell. 13: 483-91. PMID 23954752 DOI: 10.1016/J.Stem.2013.07.018 |
0.475 |
|
| 2013 |
Ikeda F, Lahav G. Signal transduction and signaling networks. Molecular Biology of the Cell. 24: 676. PMID 23486400 DOI: 10.1091/Mbc.E12-12-0877 |
0.439 |
|
| 2013 |
Purvis JE, Lahav G. Encoding and decoding cellular information through signaling dynamics. Cell. 152: 945-56. PMID 23452846 DOI: 10.1016/J.Cell.2013.02.005 |
0.397 |
|
| 2013 |
Kafri R, Levy J, Ginzberg MB, Oh S, Lahav G, Kirschner MW. Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle. Nature. 494: 480-3. PMID 23446419 DOI: 10.1038/Nature11897 |
0.443 |
|
| 2013 |
Karanam K, Loewer A, Lahav G. Dynamics of the DNA damage response: insights from live-cell imaging. Briefings in Functional Genomics. 12: 109-17. PMID 23292635 DOI: 10.1093/Bfgp/Els059 |
0.456 |
|
| 2013 |
Liu JC, Guan X, Ryan JA, Rivera AG, Mock C, Agrawal V, Letai A, Lerou PH, Lahav G. Erratum: High Mitochondrial Priming Sensitizes hESCs to DNA-Damage-Induced Apoptosis (Cell Stem Cell (2013) 13(4) (483–491) (S1934590913003639)(10.1016/j.stem.2013.07.018)) Cell Stem Cell. 13. DOI: 10.1016/J.Stem.2013.10.004 |
0.369 |
|
| 2012 |
Karanam K, Kafri R, Loewer A, Lahav G. Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. Molecular Cell. 47: 320-9. PMID 22841003 DOI: 10.1016/J.Molcel.2012.05.052 |
0.453 |
|
| 2012 |
Purvis JE, Karhohs KW, Mock C, Batchelor E, Loewer A, Lahav G. p53 dynamics control cell fate. Science (New York, N.Y.). 336: 1440-4. PMID 22700930 DOI: 10.1126/Science.1218351 |
0.796 |
|
| 2012 |
Orth JD, Loewer A, Lahav G, Mitchison TJ. Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction. Molecular Biology of the Cell. 23: 567-76. PMID 22171325 DOI: 10.1091/Mbc.E11-09-0781 |
0.439 |
|
| 2011 |
Loewer A, Lahav G. We are all individuals: causes and consequences of non-genetic heterogeneity in mammalian cells. Current Opinion in Genetics & Development. 21: 753-8. PMID 22005655 DOI: 10.1016/J.Gde.2011.09.010 |
0.459 |
|
| 2011 |
Batchelor E, Lahav G. Suppressing variation in synthetic circuits. Molecular Systems Biology. 7: 520. PMID 21811231 DOI: 10.1038/Msb.2011.53 |
0.692 |
|
| 2011 |
Batchelor E, Loewer A, Mock C, Lahav G. Stimulus-dependent dynamics of p53 in single cells. Molecular Systems Biology. 7: 488. PMID 21556066 DOI: 10.1038/Msb.2011.20 |
0.76 |
|
| 2010 |
Toettcher JE, Mock C, Batchelor E, Loewer A, Lahav G. A synthetic-natural hybrid oscillator in human cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 17047-52. PMID 20837528 DOI: 10.1073/Pnas.1005615107 |
0.746 |
|
| 2010 |
Inuzuka H, Tseng A, Gao D, Zhai B, Zhang Q, Shaik S, Wan L, Ang XL, Mock C, Yin H, Stommel JM, Gygi S, Lahav G, Asara J, Xiao ZX, et al. Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase. Cancer Cell. 18: 147-59. PMID 20708156 DOI: 10.1016/J.Ccr.2010.06.015 |
0.422 |
|
| 2010 |
Geva-Zatorsky N, Dekel E, Batchelor E, Lahav G, Alon U. Fourier analysis and systems identification of the p53 feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 107: 13550-5. PMID 20622152 DOI: 10.1073/Pnas.1001107107 |
0.769 |
|
| 2010 |
Loewer A, Batchelor E, Gaglia G, Lahav G. Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells. Cell. 142: 89-100. PMID 20598361 DOI: 10.1016/J.Cell.2010.05.031 |
0.79 |
|
| 2009 |
Tzur A, Kafri R, LeBleu VS, Lahav G, Kirschner MW. Cell growth and size homeostasis in proliferating animal cells. Science (New York, N.Y.). 325: 167-71. PMID 19589995 DOI: 10.1126/Science.1174294 |
0.398 |
|
| 2009 |
Batchelor E, Loewer A, Lahav G. The ups and downs of p53: understanding protein dynamics in single cells. Nature Reviews. Cancer. 9: 371-7. PMID 19360021 DOI: 10.1038/Nrc2604 |
0.753 |
|
| 2009 |
Toettcher JE, Loewer A, Ostheimer GJ, Yaffe MB, Tidor B, Lahav G. Distinct mechanisms act in concert to mediate cell cycle arrest Proceedings of the National Academy of Sciences of the United States of America. 106: 785-790. PMID 19139404 DOI: 10.1073/Pnas.0806196106 |
0.549 |
|
| 2008 |
Lahav G. Oscillations by the p53-Mdm2 feedback loop. Advances in Experimental Medicine and Biology. 641: 28-38. PMID 18783169 DOI: 10.1007/978-0-387-09794-7_2 |
0.606 |
|
| 2008 |
Batchelor E, Mock CS, Bhan I, Loewer A, Lahav G. Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage. Molecular Cell. 30: 277-89. PMID 18471974 DOI: 10.1016/J.Molcel.2008.03.016 |
0.745 |
|
| 2006 |
Sigal A, Milo R, Cohen A, Geva-Zatorsky N, Klein Y, Alaluf I, Swerdlin N, Perzov N, Danon T, Liron Y, Raveh T, Carpenter AE, Lahav G, Alon U. Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nature Methods. 3: 525-31. PMID 16791210 DOI: 10.1038/Nmeth892 |
0.747 |
|
| 2006 |
Geva-Zatorsky N, Rosenfeld N, Itzkovitz S, Milo R, Sigal A, Dekel E, Yarnitzky T, Liron Y, Polak P, Lahav G, Alon U. Oscillations and variability in the p53 system. Molecular Systems Biology. 2: 2006.0033. PMID 16773083 DOI: 10.1038/Msb4100068 |
0.793 |
|
| 2006 |
Loewer A, Lahav G. Cellular conference call: external feedback affects cell-fate decisions. Cell. 124: 1128-30. PMID 16564006 DOI: 10.1016/J.Cell.2006.03.010 |
0.441 |
|
| 2004 |
Lahav G. The strength of indecisiveness: oscillatory behavior for better cell fate determination. Science's Stke : Signal Transduction Knowledge Environment. 2004: pe55. PMID 15613687 DOI: 10.1126/Stke.2642004Pe55 |
0.435 |
|
| 2004 |
Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nature Genetics. 36: 147-50. PMID 14730303 DOI: 10.1038/Ng1293 |
0.804 |
|
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