Wadie F. Bahou - Publications

Affiliations: 
Genetics Stony Brook University, Stony Brook, NY, United States 
Area:
Virology Biology, Molecular Biology, Genetics

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sheriff J, Malone LE, Avila C, Zigomalas A, Bluestein D, Bahou WF. Shear-Induced Platelet Activation is Sensitive to Age and Calcium Availability: A Comparison of Adult and Cord Blood. Cellular and Molecular Bioengineering. 13: 575-590. PMID 33281988 DOI: 10.1007/S12195-020-00628-X  0.326
2020 Sims MC, Mayer L, Collins J, Bariana T, Megy K, Lavenu-Bombled C, Seyres D, Kollipara L, Burden F, Greene D, Lee D, Rodriguez-Romera A, Alessi MC, Astle WJ, Bahou W, et al. Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome. Blood. PMID 32693407 DOI: 10.1182/Blood.2019004776  0.375
2019 Ngo ATP, Sheriff J, Rocheleau AD, Bucher M, Jones KR, Sepp AI, Malone LE, Zigomalas A, Maloyan A, Bahou WF, Bluestein D, McCarty OJT, Haley KM. Assessment of neonatal, cord, and adult platelet granule trafficking and secretion. Platelets. 1-11. PMID 30810440 DOI: 10.1080/09537104.2019.1573314  0.414
2018 Nesbitt NM, Zheng X, Li Z, Manso JA, Yen WY, Malone LE, Ripoll-Rozada J, Pereira PJB, Mantle TJ, Wang J, Bahou WF. In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency. The Journal of Biological Chemistry. PMID 29487133 DOI: 10.1074/Jbc.Ra118.001803  0.333
2016 Wu S, Li Z, Gnatenko DV, Zhang B, Zhao L, Malone LE, Markova N, Mantle TJ, Nesbitt NM, Bahou WF. BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans. Blood. PMID 27207795 DOI: 10.1182/Blood-2016-02-696997  0.414
2015 Wu S, Li Z, Gnatenko DV, Zhang B, Zhao L, Malone L, Markova N, Mantle T, Nesbitt N, Bahou WF. Blvrb Mutation Induces Thrombocytosis Via Redox Dysregulation in the Heme Degradation Pathway Blood. 126: 74-74. DOI: 10.1182/Blood.V126.23.74.74  0.347
2013 Bahou WF. Genetic dissection of platelet function in health and disease using systems biology. Hematology/Oncology Clinics of North America. 27: 443-63. PMID 23714307 DOI: 10.1016/J.Hoc.2013.03.002  0.385
2013 Kalashnyk O, Petrova Y, Lykhmus O, Mikhalovska L, Mikhalovsky S, Zhukova A, Gnatenko D, Bahou W, Komisarenko S, Skok M. Expression, function and cooperating partners of protease-activated receptor type 3 in vascular endothelial cells and B lymphocytes studied with specific monoclonal antibody. Molecular Immunology. 54: 319-26. PMID 23352962 DOI: 10.1016/J.Molimm.2012.12.021  0.311
2013 Huang E, Zhu W, Dhundale A, Bahou WF, Gnatenko DV. Platelet genetic biomarker quantification: comparison of fluorescent microspheres and PCR platforms. Thrombosis and Haemostasis. 109: 337-46. PMID 23223848 DOI: 10.1160/Th12-04-0257  0.376
2012 Xu X, Gnatenko DV, Ju J, Hitchcock IS, Martin DW, Zhu W, Bahou WF. Systematic analysis of microRNA fingerprints in thrombocythemic platelets using integrated platforms. Blood. 120: 3575-85. PMID 22869791 DOI: 10.1182/Blood-2012-02-411264  0.314
2012 Bahou WF. Platelet systems biology using integrated genetic and proteomic platforms. Thrombosis Research. 129: S38-45. PMID 22682131 DOI: 10.1016/S0049-3848(12)70014-2  0.404
2011 Sitaraman V, Hearing P, Ward CB, Gnatenko DV, Wimmer E, Mueller S, Skiena S, Bahou WF. Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector. Proceedings of the National Academy of Sciences of the United States of America. 108: 14294-9. PMID 21844368 DOI: 10.1073/Pnas.1102883108  0.677
2010 Williams MS, Weiss EJ, Sabatine MS, Simon DI, Bahou WF, Becker LC, Parise LV, Dauerman HL, French PA, Smyth SS, Becker RC. Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2372-84. PMID 21084706 DOI: 10.1161/Atvbaha.110.218131  0.405
2009 Senzel L, Gnatenko DV, Bahou WF. The platelet proteome. Current Opinion in Hematology. 16: 329-33. PMID 19550320 DOI: 10.1097/Moh.0B013E32832E9Dc6  0.406
2009 Gnatenko DV, Dunn JJ, Schwedes J, Bahou WF. Transcript profiling of human platelets using microarray and serial analysis of gene expression (SAGE). Methods in Molecular Biology (Clifton, N.J.). 496: 245-72. PMID 18839115 DOI: 10.1007/978-1-59745-553-4_16  0.423
2008 Damon AL, Scudder LE, Gnatenko DV, Sitaraman V, Hearing P, Jesty J, Bahou WF. Altered bioavailability of platelet-derived factor VIII during thrombocytosis reverses phenotypic efficacy in haemophilic mice. Thrombosis and Haemostasis. 100: 1111-22. PMID 19132238 DOI: 10.1160/Th08-04-0242  0.709
2008 Senzel L, Gnatenko DV, Bahou WF. Genomic and proteomic applications in diagnosis of platelet disorders and classification. Seminars in Thrombosis and Hemostasis. 34: 532-8. PMID 19085652 DOI: 10.1055/S-0028-1103364  0.383
2008 Gnatenko DV, Zhu W, Bahou WF. Multiplexed genetic profiling of human blood platelets using fluorescent microspheres. Thrombosis and Haemostasis. 100: 929-36. PMID 18989540 DOI: 10.1160/Th08-05-0305  0.432
2007 Senzel L, Gnatenko DV, Bahou WF. Platelet transcriptome and cardiovascular disease. Future Cardiology. 3: 391-8. PMID 19804230 DOI: 10.2217/14796678.3.4.391  0.386
2007 Gnatenko DV, Perrotta PL, Ji C, Zhu W, Bahou WF. Platelet Gene/Protein Expression Analyses Using an Integrated Platform. Blood. 110: 3645-3645. DOI: 10.1182/Blood.V110.11.3645.3645  0.392
2007 Damon AL, Jesty J, Scudder LE, Gnatenko DV, Bahou WF. Megakaryocyte/Platelet-Restricted FVIII Expression Using a Platelet Factor 4 Promoter: Determination of Activation State and In Vivo Efficacy during Thrombocytosis. Blood. 110: 1142-1142. DOI: 10.1182/Blood.V110.11.1142.1142  0.442
2007 Gnatenko DV, Zhu W, Dhundale A, Bahou WF. Class Prediction Models of Thrombocytosis Using Gene Profiling. Blood. 110: 100-100. DOI: 10.1182/Blood.V110.11.100.100  0.385
2006 Gnatenko DV, Perrotta PL, Bahou WF. Proteomic approaches to dissect platelet function: Half the story. Blood. 108: 3983-91. PMID 16926286 DOI: 10.1182/Blood-2006-06-026518  0.421
2006 Gnatenko DV, Bahou WF. Recent Advances in Platelet Transcriptomics Transfusion Medicine and Hemotherapy. 33: 217-226. DOI: 10.1159/000091371  0.421
2005 Gnatenko DV, Cupit LD, Huang EC, Dhundale A, Perrotta PL, Bahou WF. Platelets express steroidogenic 17beta-hydroxysteroid dehydrogenases. Distinct profiles predict the essential thrombocythemic phenotype. Thrombosis and Haemostasis. 94: 412-21. PMID 16113833 DOI: 10.1160/Th05-01-0037  0.433
2005 Rosenfeldt MT, Valentino M, Labruzzo S, Scudder L, Pavlaki M, Cao J, Vacirca J, Bahou WF, Zucker S. The organomercurial 4-aminophenylmercuric acetate, independent of matrix metalloproteinases, induces dose-dependent activation/inhibition of platelet aggregation. Thrombosis and Haemostasis. 93: 326-30. PMID 15711750 DOI: 10.1160/Th04-08-0541  0.408
2004 Cupit LD, Schmidt VA, Gnatenko DV, Bahou WF. Expression of protease activated receptor 3 (PAR3) is upregulated by induction of megakaryocyte phenotype in human erythroleukemia (HEL) cells. Experimental Hematology. 32: 991-9. PMID 15504554 DOI: 10.1016/J.Exphem.2004.07.005  0.434
2004 Cupit LD, Schmidt VA, Miller F, Bahou WF. Distinct PAR/IQGAP expression patterns during murine development: implications for thrombin-associated cytoskeletal reorganization. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 618-29. PMID 15457341 DOI: 10.1007/S00335-004-2370-8  0.352
2004 Bahou WF, Gnatenko DV. Platelet transcriptome: the application of microarray analysis to platelets. Seminars in Thrombosis and Hemostasis. 30: 473-84. PMID 15354268 DOI: 10.1055/S-2004-833482  0.433
2004 Gnatenko DV, Wu Y, Jesty J, Damon AL, Hearing P, Bahou WF. Expression of therapeutic levels of factor VIII in hemophilia A mice using a novel adeno/adeno-associated hybrid virus. Thrombosis and Haemostasis. 92: 317-27. PMID 15269828 DOI: 10.1160/Th04-02-0068  0.372
2004 Bahou WF, Scudder L, Rubenstein D, Jesty J. A shear-restricted pathway of platelet procoagulant activity is regulated by IQGAP1. The Journal of Biological Chemistry. 279: 22571-7. PMID 15026422 DOI: 10.1074/Jbc.M402561200  0.421
2003 Bahou WF. Protease-activated receptors. Current Topics in Developmental Biology. 54: 343-69. PMID 12696755 DOI: 10.1016/S0070-2153(03)54014-5  0.359
2003 Schmidt VA, Scudder L, Devoe CE, Bernards A, Cupit LD, Bahou WF. IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization. Blood. 101: 3021-8. PMID 12515716 DOI: 10.1182/Blood-2002-09-2807  0.467
2003 Gnatenko DV, Dunn JJ, McCorkle SR, Weissmann D, Perrotta PL, Bahou WF. Transcript profiling of human platelets using microarray and serial analysis of gene expression. Blood. 101: 2285-93. PMID 12433680 DOI: 10.1182/Blood-2002-09-2797  0.424
2002 Bahou WF. Attacked from within, blood thins. Nature Medicine. 8: 1082-3. PMID 12357241 DOI: 10.1038/Nm1002-1082  0.317
2002 Pavlaki M, Cao J, Hymowitz M, Chen WT, Bahou W, Zucker S. A conserved sequence within the propeptide domain of membrane type 1 matrix metalloproteinase is critical for function as an intramolecular chaperone. The Journal of Biological Chemistry. 277: 2740-9. PMID 11704671 DOI: 10.1074/Jbc.M108987200  0.301
2000 Sandalon Z, Gnatenko DV, Bahou WF, Hearing P. Adeno-associated virus (AAV) rep protein enhances the generation of a recombinant mini-adenovirus (Ad) utilizing an Ad/AAV hybrid virus Journal of Virology. 74: 10381-10389. PMID 11044082 DOI: 10.1128/Jvi.74.22.10381-10389.2000  0.336
2000 Cao J, Hymowitz M, Conner C, Bahou WF, Zucker S. The propeptide domain of membrane type 1-matrix metalloproteinase acts as an intramolecular chaperone when expressed in trans with the mature sequence in COS-1 cells. The Journal of Biological Chemistry. 275: 29648-53. PMID 10889191 DOI: 10.1074/Jbc.M001920200  0.316
1999 Burbelo PD, Snow DM, Bahou W, Spiegel S. MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 96: 9083-8. PMID 10430899 DOI: 10.1073/Pnas.96.16.9083  0.321
1999 Cupit LD, Schmidt VA, Bahou WF. Proteolytically activated receptor-3. A member of an emerging gene family of protease receptors expressed on vascular endothelial cells and platelets. Trends in Cardiovascular Medicine. 9: 42-8. PMID 10189966 DOI: 10.1016/S1050-1738(99)00005-5  0.396
1999 Gnatenko DV, Saenko EL, Jesty J, Cao LX, Hearing P, Bahou WF. Human factor VIII can be packaged and functionally expressed in an adeno-associated virus background: Applicability to haemophilia A gene therapy British Journal of Haematology. 104: 27-36. PMID 10027708 DOI: 10.1046/J.1365-2141.1999.01137.X  0.349
1999 Joseph K, Nakazawa Y, Bahou WF, Ghebrehiwet B, Kaplan AP. Platelet Glycoprotein Ib: A Zinc-Dependent Binding Protein for the Heavy Chain of High-Molecular-Weight Kininogen Molecular Medicine. 5: 555-563. DOI: 10.1007/Bf03401982  0.35
1998 Schmidt VA, Nierman WC, Maglott DR, Cupit LD, Moskowitz KA, Wainer JA, Bahou WF. The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a Par gene cluster and characterization in vascular endothelial cells and platelets. The Journal of Biological Chemistry. 273: 15061-8. PMID 9614115 DOI: 10.1074/Jbc.273.24.15061  0.428
1998 Zucker S, Mirza H, Conner CE, Lorenz AF, Drews MH, Bahou WF, Jesty J. Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: Conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation International Journal of Cancer. 75: 780-786. PMID 9495249 DOI: 10.1002/(Sici)1097-0215(19980302)75:5<780::Aid-Ijc19>3.0.Co;2-A  0.305
1998 Mazzucato M, Marco LD, Masotti A, Pradella P, Bahou WF, Ruggeri ZM. Characterization of the initial alpha-thrombin interaction with glycoprotein Ib alpha in relation to platelet activation. The Journal of Biological Chemistry. 273: 1880-7. PMID 9442020 DOI: 10.1074/Jbc.273.4.1880  0.305
1997 Bahou WF, Demetrick DJ. The human thrombin receptor gene and the 5q-syndrome. Leukemia & Lymphoma. 27: 1-10. PMID 9373191 DOI: 10.3109/10428199709068266  0.343
1997 Schmidt VA, Nierman WC, Feldblyum TV, Maglott DR, Bahou WF. The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13. British Journal of Haematology. 97: 523-9. PMID 9207393 DOI: 10.1046/J.1365-2141.1997.922907.X  0.363
1997 Noiri E, Hu Y, Bahou WF, Keese CR, Giaever I, Goligorsky MS. Permissive role of nitric oxide in endothelin-induced migration of endothelial cells. The Journal of Biological Chemistry. 272: 1747-52. PMID 8999856 DOI: 10.1074/Jbc.272.3.1747  0.311
1997 Mirza H, Schmidt VA, Derian CK, Jesty J, Bahou WF. Mitogenic Responses Mediated Through the Proteinase-Activated Receptor-2 Are Induced by Expressed Forms of Mast Cell α- or β-Tryptases Blood. 90: 3914-3922. DOI: 10.1182/Blood.V90.10.3914  0.35
1996 Bahou WF, Schmidt VA. Molecular characterization of proteolytically activated receptors: insights from the thrombin receptor and proteinase activated receptor-2 (PAR-2) genes. Platelets. 7: 253-60. PMID 21043659 DOI: 10.3109/09537109609023586  0.301
1996 Cao J, Rehemtulla A, Bahou W, Zucker S. Membrane Type Matrix Metalloproteinase 1 Activates Pro-gelatinase A without Furin Cleavage of the N-terminal Domain Journal of Biological Chemistry. 271: 30174-30180. PMID 8939968 DOI: 10.1074/Jbc.271.47.30174  0.31
1996 Mirza H, Yatsula V, Bahou WF. The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. The Journal of Clinical Investigation. 97: 1705-14. PMID 8601636 DOI: 10.1172/Jci118597  0.367
1996 Schmidt VA, Vitale E, Bahou WF. Genomic Cloning and Characterization of the Human Thrombin Receptor Gene Journal of Biological Chemistry. 271: 9307-9312. DOI: 10.1074/Jbc.271.16.9307  0.371
1996 Mirza H, Yatsula V, Bahou WF. The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells: Characterization and evidence for coupling to the thrombin receptor (TR) Journal of the American College of Cardiology. 27: 384. DOI: 10.1016/S0735-1097(96)82464-8  0.319
1995 Meng H, Tonnesen MG, Marchese MJ, Clark RA, Bahou WF, Gruber BL. Mast cells are potent regulators of endothelial cell adhesion molecule ICAM-1 and VCAM-1 expression. Journal of Cellular Physiology. 165: 40-53. PMID 7559805 DOI: 10.1002/Jcp.1041650106  0.336
1995 Zucker S, Conner C, DiMassmo BI, Ende H, Drews M, Seiki M, Bahou WF. Thrombin induces the activation of progelatinase A in vascular endothelial cells. Physiologic regulation of angiogenesis. The Journal of Biological Chemistry. 270: 23730-8. PMID 7559545 DOI: 10.1074/Jbc.270.40.23730  0.374
1994 Bahou W, Kutok J, Wong A, Potter C, Coller B. Identification of a novel thrombin receptor sequence required for activation-dependent responses Blood. 84: 4195-4202. DOI: 10.1182/Blood.V84.12.4195.Bloodjournal84124195  0.36
1994 Bahou W, Potter C, Mirza H. The VLA-2 (alpha 2 beta 1) I domain functions as a ligand-specific recognition sequence for endothelial cell attachment and spreading: molecular and functional characterization Blood. 84: 3734-3741. DOI: 10.1182/Blood.V84.11.3734.Bloodjournal84113734  0.345
1993 Bahou WF, Coller BS, Potter CL, Norton KJ, Kutok JL, Goligorsky MS. The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation. The Journal of Clinical Investigation. 91: 1405-13. PMID 8386186 DOI: 10.1172/Jci116344  0.371
1993 Bahou W, Nierman W, Durkin A, Potter C, Demetrick D. Chromosomal assignment of the human thrombin receptor gene: localization to region q13 of chromosome 5 Blood. 82: 1532-1537. DOI: 10.1182/Blood.V82.5.1532.Bloodjournal8251532  0.31
1991 Cooney KA, Nichols WC, Bruck ME, Bahou WF, Shapiro AD, Bowie EJW, Gralnick HR, Ginsburg D. The molecular defect in type IIB von Willebrand disease: Identification of four potential missense mutations within the putative GpIb binding domain Journal of Clinical Investigation. 87: 1227-1233. PMID 1672694 DOI: 10.1172/Jci115123  0.316
1988 Bahou W, Bowie E, Fass D, Ginsburg D. Molecular genetic analysis of porcine von Willebrand disease: tight linkage to the von Willebrand factor locus Blood. 72: 308-313. DOI: 10.1182/Blood.V72.1.308.308  0.332
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