Inez Rogatsky - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Molecular Biology, Immunology

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Fadel L, Dacic M, Fonda V, Sokolsky BA, Quagliarini F, Rogatsky I, Uhlenhaut NH. Modulating glucocorticoid receptor actions in physiology and pathology: Insights from coregulators. Pharmacology & Therapeutics. 108531. PMID 37717739 DOI: 10.1016/j.pharmthera.2023.108531  0.324
2022 Dacic M, Shibu G, Rogatsky I. Physiological Convergence and Antagonism Between GR and PPARγ in Inflammation and Metabolism. Advances in Experimental Medicine and Biology. 1390: 123-141. PMID 36107316 DOI: 10.1007/978-3-031-11836-4_7  0.372
2022 Thevkar-Nagesh P, Habault J, Voisin M, Ruff SE, Ha S, Ruoff R, Chen X, Rawal S, Zahr T, Szabo G, Rogatsky I, Fisher EA, Garabedian MJ. Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation. Plos One. 17: e0272986. PMID 36054206 DOI: 10.1371/journal.pone.0272986  0.335
2021 Mimouna S, Rollins DA, Shibu G, Tharmalingam B, Deochand DK, Chen X, Oliver D, Chinenov Y, Rogatsky I. Transcription cofactor GRIP1 differentially affects myeloid cell-driven neuroinflammation and response to IFN-β therapy. The Journal of Experimental Medicine. 218. PMID 33045064 DOI: 10.1084/jem.20192386  0.309
2020 Yu L, Zhang B, Deochand D, Sacta MA, Coppo M, Shang Y, Guo Z, Zeng X, Rollins DA, Tharmalingam B, Li R, Chinenov Y, Rogatsky I, Hu X. Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression. Nature Communications. 11: 2286. PMID 32385332 DOI: 10.1038/S41467-020-16209-5  0.504
2019 Rollins DA, Rogatsky I. Dual Cross-Linking Chromatin Immunoprecipitation Protocol for Next-Generation Sequencing (ChIPseq) in Macrophages. Methods in Molecular Biology (Clifton, N.J.). 1951: 87-98. PMID 30825146 DOI: 10.1007/978-1-4939-9130-3_7  0.381
2018 Sacta MA, Tharmalingam B, Coppo M, Rollins DA, Deochand DK, Benjamin B, Yu L, Zhang B, Hu X, Li R, Chinenov Y, Rogatsky I. Gene-specific mechanisms direct Glucocorticoid Receptor-driven repression of inflammatory response genes in macrophages. Elife. 7. PMID 29424686 DOI: 10.7554/Elife.34864  0.522
2017 Rollins DA, Kharlyngdoh JB, Coppo M, Tharmalingam B, Mimouna S, Guo Z, Sacta MA, Pufall MA, Fisher RP, Hu X, Chinenov Y, Rogatsky I. Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages. Nature Communications. 8: 1739. PMID 29170386 DOI: 10.1038/S41467-017-01569-2  0.503
2016 Coppo M, Chinenov Y, Sacta MA, Rogatsky I. The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis. Nature Communications. 7: 12254. PMID 27464507 DOI: 10.1038/Ncomms12254  0.423
2016 Shang Y, Coppo M, He T, Ning F, Yu L, Kang L, Zhang B, Ju C, Qiao Y, Zhao B, Gessler M, Rogatsky I, Hu X. The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation. Nature Immunology. PMID 27322654 DOI: 10.1038/Ni.3486  0.546
2016 Greulich F, Charlotte Hemmer M, Rollins DA, Rogatsky I, Henriette Uhlenhaut N. There goes the neighborhood: Assembly of transcriptional complexes during the regulation of metabolism and inflammation by the Glucocorticoid Receptor. Steroids. PMID 27192428 DOI: 10.1016/J.Steroids.2016.05.003  0.476
2016 Sacta MA, Chinenov Y, Rogatsky I. Glucocorticoid Signaling: An Update from a Genomic Perspective. Annual Review of Physiology. 78: 155-80. PMID 26667074 DOI: 10.1146/Annurev-Physiol-021115-105323  0.423
2015 Rollins DA, Coppo M, Rogatsky I. Minireview: nuclear receptor coregulators of the p160 family: insights into inflammation and metabolism. Molecular Endocrinology (Baltimore, Md.). 29: 502-17. PMID 25647480 DOI: 10.1210/Me.2015-1005  0.38
2014 Chinenov Y, Coppo M, Gupte R, Sacta MA, Rogatsky I. Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages. Bmc Genomics. 15: 656. PMID 25099603 DOI: 10.1186/1471-2164-15-656  0.486
2014 Rogatsky I, Adelman K. Preparing the first responders: building the inflammatory transcriptome from the ground up. Molecular Cell. 54: 245-54. PMID 24766888 DOI: 10.1016/J.Molcel.2014.03.038  0.494
2014 Rogatsky I, Chandrasekaran U, Manni M, Yi W, Pernis AB. Epigenetics and the IRFs: a complex interplay in the control of immunity and autoimmunity. Autoimmunity. 47: 242-55. PMID 24215615 DOI: 10.3109/08916934.2013.853050  0.384
2013 Gupte R, Muse GW, Chinenov Y, Adelman K, Rogatsky I. Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle. Proceedings of the National Academy of Sciences of the United States of America. 110: 14616-21. PMID 23950223 DOI: 10.1073/Pnas.1309898110  0.546
2013 Chinenov Y, Gupte R, Rogatsky I. Nuclear receptors in inflammation control: repression by GR and beyond. Molecular and Cellular Endocrinology. 380: 55-64. PMID 23623868 DOI: 10.1016/J.Mce.2013.04.006  0.54
2012 Chinenov Y, Gupte R, Dobrovolna J, Flammer JR, Liu B, Michelassi FE, Rogatsky I. Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids. Proceedings of the National Academy of Sciences of the United States of America. 109: 11776-81. PMID 22753499 DOI: 10.1073/Pnas.1206059109  0.77
2012 Dobrovolna J, Chinenov Y, Kennedy MA, Liu B, Rogatsky I. Glucocorticoid-dependent phosphorylation of the transcriptional coregulator GRIP1. Molecular and Cellular Biology. 32: 730-9. PMID 22158970 DOI: 10.1128/Mcb.06473-11  0.475
2011 Flammer JR, Rogatsky I. Minireview: Glucocorticoids in autoimmunity: unexpected targets and mechanisms. Molecular Endocrinology (Baltimore, Md.). 25: 1075-86. PMID 21511881 DOI: 10.1210/Me.2011-0068  0.768
2011 Rogatsky I, Chinenov Y, Gupte R, Flammer JR, Dobrovolna J, Kennedy MA, Liu B. CS13-5. Anti-inflammatory actions of glucocorticoids: the role of transcriptional coregulator GRIP1 in shaping macrophage transcriptome and systemic inflammation Cytokine. 56: 100. DOI: 10.1016/J.Cyto.2011.07.387  0.741
2010 Flammer JR, Dobrovolna J, Kennedy MA, Chinenov Y, Glass CK, Ivashkiv LB, Rogatsky I. The type I interferon signaling pathway is a target for glucocorticoid inhibition. Molecular and Cellular Biology. 30: 4564-74. PMID 20679482 DOI: 10.1128/Mcb.00146-10  0.783
2010 Adelman K, Rogatsky I. RNA polymerase II stalling mediates cytokine gene expression. Cell Cycle (Georgetown, Tex.). 9: 630-1. PMID 20107307 DOI: 10.4161/Cc.9.4.10841  0.356
2010 Bhandare R, Damera G, Banerjee A, Flammer JR, Keslacy S, Rogatsky I, Panettieri RA, Amrani Y, Tliba O. Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells. American Journal of Respiratory Cell and Molecular Biology. 42: 9-15. PMID 19805480 DOI: 10.1165/Rcmb.2009-0239Rc  0.766
2010 Flammer JR, Kennedy MA, Reily M, Chinenov Y, Ivashkiv LB, Rogatsky I. PL2-6 A dual action of glucocorticoids on the type I interferon network Cytokine. 52: 37. DOI: 10.1016/J.Cyto.2010.07.167  0.712
2010 Flammer JR, Kennedy MA, Chinenov Y, Ivashkiv LB, Rogatsky I. PS1-56 Type I interferon-dependent gene expression is a target for glucocorticoid inhibition Cytokine. 52: 29. DOI: 10.1016/J.Cyto.2010.07.128  0.743
2009 Adelman K, Kennedy MA, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, Rogatsky I. Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling. Proceedings of the National Academy of Sciences of the United States of America. 106: 18207-12. PMID 19820169 DOI: 10.1073/Pnas.0910177106  0.525
2009 Kennedy M, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, Adelman K, Rogatsky I. Immediate mediators of the inflammatory response are poised for rapid gene activation through RNA polymerase stalling Cytokine. 48: 25. DOI: 10.1016/J.Cyto.2009.07.097  0.412
2008 Chinenov Y, Sacta MA, Cruz AR, Rogatsky I. GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression. Proceedings of the National Academy of Sciences of the United States of America. 105: 20185-90. PMID 19074285 DOI: 10.1073/Pnas.0810863105  0.453
2008 Chen W, Dang T, Blind RD, Wang Z, Cavasotto CN, Hittelman AB, Rogatsky I, Logan SK, Garabedian MJ. Glucocorticoid receptor phosphorylation differentially affects target gene expression. Molecular Endocrinology (Baltimore, Md.). 22: 1754-66. PMID 18483179 DOI: 10.1210/Me.2007-0219  0.445
2008 Torra IP, Ismaili N, Feig JE, Xu CF, Cavasotto C, Pancratov R, Rogatsky I, Neubert TA, Fisher EA, Garabedian MJ. Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages. Molecular and Cellular Biology. 28: 2626-36. PMID 18250151 DOI: 10.1128/Mcb.01575-07  0.419
2008 Flammer JR, Kennedy MA, Chinenov Y, Ivashkiv LB, Rogatsky I. 187 Glucocorticoid regulation of the type I interferon-JAK/STAT signaling pathway Cytokine. 43: 283-284. DOI: 10.1016/J.Cyto.2008.07.249  0.74
2008 Kennedy MA, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, Adelman K, Rogatsky I. 172 Regulation of TNFα gene transcription at the post-initiation step Cytokine. 43: 280. DOI: 10.1016/J.Cyto.2008.07.234  0.424
2007 Chinenov Y, Rogatsky I. Glucocorticoids and the innate immune system: crosstalk with the toll-like receptor signaling network. Molecular and Cellular Endocrinology. 275: 30-42. PMID 17576036 DOI: 10.1016/J.Mce.2007.04.014  0.511
2007 Reily MM, Chinenov Y, Kennedy MA, Rogatsky I. 126 Antagonism between the Glucocorticoid Receptor and Interferon Regulatory Factor-3: Transcriptional Coregulator GRIP1 in Immunosuppression Cytokine. 39: 34-35. DOI: 10.1016/J.Cyto.2007.07.131  0.417
2006 Rogatsky I, Ivashkiv LB. Glucocorticoid modulation of cytokine signaling. Tissue Antigens. 68: 1-12. PMID 16774534 DOI: 10.1111/J.1399-0039.2006.00599.X  0.558
2006 Takayama S, Rogatsky I, Schwarcz LE, Darimont BD. The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-beta-catenin complex. The Journal of Biological Chemistry. 281: 17856-63. PMID 16644723 DOI: 10.1074/Jbc.M602290200  0.395
2006 Reily MM, Pantoja C, Hu X, Chinenov Y, Rogatsky I. The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression. The Embo Journal. 25: 108-17. PMID 16362036 DOI: 10.1038/Sj.Emboj.7600919  0.539
2006 Chen W, Rogatsky I, Garabedian MJ. MED14 and MED1 differentially regulate target-specific gene activation by the glucocorticoid receptor. Molecular Endocrinology (Baltimore, Md.). 20: 560-72. PMID 16239257 DOI: 10.1210/Me.2005-0318  0.49
2004 Tee MK, Rogatsky I, Tzagarakis-Foster C, Cvoro A, An J, Christy RJ, Yamamoto KR, Leitman DC. Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Molecular Biology of the Cell. 15: 1262-72. PMID 14699072 DOI: 10.1091/Mbc.E03-06-0360  0.427
2003 Rogatsky I, Wang JC, Derynck MK, Nonaka DF, Khodabakhsh DB, Haqq CM, Darimont BD, Garabedian MJ, Yamamoto KR. Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 100: 13845-50. PMID 14617768 DOI: 10.1073/Pnas.2336092100  0.497
2003 Rogatsky I. Drug discovery for inflammatory diseases. Expert Opinion On Biological Therapy. 3: 1001-4. PMID 12943459 DOI: 10.1517/14712598.3.6.1001  0.39
2002 Rogatsky I, Luecke HF, Leitman DC, Yamamoto KR. Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts. Proceedings of the National Academy of Sciences of the United States of America. 99: 16701-6. PMID 12481024 DOI: 10.1073/Pnas.262671599  0.408
2002 Markus SM, Taneja SS, Logan SK, Li W, Ha S, Hittelman AB, Rogatsky I, Garabedian MJ. Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus. Molecular Biology of the Cell. 13: 670-82. PMID 11854421 DOI: 10.1091/Mbc.01-10-0513  0.395
2001 Rogatsky I, Zarember KA, Yamamoto KR. Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. The Embo Journal. 20: 6071-83. PMID 11689447 DOI: 10.1093/Emboj/20.21.6071  0.463
2000 Fryer CJ, Kinyamu HK, Rogatsky I, Garabedian MJ, Archer TK. Selective activation of the glucocorticoid receptor by steroid antagonists in human breast cancer and osteosarcoma cells Journal of Biological Chemistry. 275: 17771-17777. PMID 10748103 DOI: 10.1074/Jbc.M908729199  0.405
1999 Rogatsky I, Trowbridge JM, Garabedian MJ. Potentiation of human estrogen receptor alpha transcriptional activation through phosphorylation of serines 104 and 106 by the cyclin A-CDK2 complex. The Journal of Biological Chemistry. 274: 22296-302. PMID 10428798 DOI: 10.1074/Jbc.274.32.22296  0.382
1999 Rogatsky I, Hittelman AB, Pearce D, Garabedian MJ. Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids. Molecular and Cellular Biology. 19: 5036-49. PMID 10373553 DOI: 10.1128/Mcb.19.7.5036  0.471
1998 Rogatsky I, Waase CLM, Garabedian MJ. Phosphorylation and inhibition of rat glucocorticoid receptor transcriptional activation by glycogen synthase kinase-3 (GSK-3): Species- specific differences between human and rat glucocorticoid receptor signaling as revealed through GSK-3 phosphorylation Journal of Biological Chemistry. 273: 14315-14321. PMID 9603939 DOI: 10.1074/Jbc.273.23.14315  0.405
1998 Rogatsky I, Logan SK, Garabedian MJ. Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase Proceedings of the National Academy of Sciences of the United States of America. 95: 2050-2055. PMID 9482836 DOI: 10.1073/Pnas.95.5.2050  0.424
1997 Trowbridge JM, Rogatsky I, Garabedian MJ. Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex. Proceedings of the National Academy of Sciences of the United States of America. 94: 10132-7. PMID 9294175 DOI: 10.1073/Pnas.94.19.10132  0.395
1997 Krstic MD, Rogatsky I, Yamamoto KR, Garabedian MJ. Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor. Molecular and Cellular Biology. 17: 3947-54. PMID 9199329 DOI: 10.1128/Mcb.17.7.3947  0.379
1997 Rogatsky I, Trowbridge JM, Garabedian MJ. Glucocorticoid receptor-mediated cell cycle arrest is achieved through distinct cell-specific transcriptional regulatory mechanisms. Molecular and Cellular Biology. 17: 3181-93. PMID 9154817 DOI: 10.1128/Mcb.17.6.3181  0.422
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