Karlyne M. Reilly - Publications

Affiliations: 
Biomedical Sciences The George Washington University, Washington, DC, United States 
Area:
Molecular Biology, Genetics

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ahmed S, Wedekind MF, Del Rivero J, Raygada M, Lockridge R, Glod JW, Flowers C, Thomas BJ, Bernstein DB, Kapustina OB, Jain A, Miettinen M, Raffeld M, Xi L, Tyagi M, ... ... Reilly KM, et al. Longitudinal Natural History Study of Children and Adults with Rare Solid Tumors: Initial Results for First 200 Participants. Cancer Research Communications. PMID 37966258 DOI: 10.1158/2767-9764.CRC-23-0247  0.316
2022 Yuan M, Eberhart CG, Pratilas CA, Blakeley JO, Davis C, Stojanova M, Reilly K, Meeker AK, Heaphy CM, Rodriguez FJ. Therapeutic Vulnerability to ATR Inhibition in Concurrent and -Deficient/ALT-Positive High-Grade Solid Tumors. Cancers. 14. PMID 35740680 DOI: 10.3390/cancers14123015  0.37
2022 Fernández-Rodríguez J, Creus-Bachiller E, Zhang X, Martínez-Iniesta M, Ortega-Bertran S, Guha R, Thomas CJ, Wallace MR, Romagosa C, Salazar-Huayna L, Reilly KM, Blakeley JO, Serra-Musach J, Pujana MA, Serra E, et al. A high-throughput screening platform identifies novel combination treatments for Malignant Peripheral Nerve Sheath Tumors. Molecular Cancer Therapeutics. PMID 35511749 DOI: 10.1158/1535-7163.MCT-21-0947  0.362
2020 Shetty I, Fuller S, Raygada M, Merino MJ, Thomas BJ, Widemann BC, Reilly KM, Pacak K, Del Rivero J. Adrenocortical carcinoma masquerading as pheochromocytoma: a histopathologic dilemma. Endocrinology, Diabetes & Metabolism Case Reports. 2020. PMID 31917677 DOI: 10.1530/Edm-19-0147  0.325
2020 Yuan M, Reilly K, Pratilas C, Heaphy C, Rodriguez F. NFB-01. FUNCTIONAL CHARACTERIZATION OF ATRX LOSS IN NF1-ASSOCIATED GLIOMA AND MPNST Neuro-Oncology. 22: iii417-iii418. DOI: 10.1093/neuonc/noaa222.605  0.319
2019 Ferner RE, Bakker A, Elgersma Y, Evans DGR, Giovannini M, Legius E, Lloyd A, Messiaen LM, Plotkin S, Reilly KM, Schindeler A, Smith MJ, Ullrich NJ, Widemann B, Sherman LS. From process to progress-2017 International Conference on Neurofibromatosis 1, Neurofibromatosis 2 and Schwannomatosis. American Journal of Medical Genetics. Part A. PMID 30908866 DOI: 10.1002/Ajmg.A.61112  0.442
2019 Thomas B, Fuller S, Ilanchezhian M, Allen D, Allen T, Weiner L, Wisch L, Sherri D, Gillespie A, Raygada M, Arnaldez F, Reilly K, Glod J, Widemann B, Del Rivero J. SUN-341 A Natural History Study for Rare Tumors: An Avenue for Discovering and Understanding Endocrine Cancers Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-341  0.407
2017 Kim A, Stewart DR, Reilly KM, Viskochil D, Miettinen MM, Widemann BC. Malignant Peripheral Nerve Sheath Tumors State of the Science: Leveraging Clinical and Biological Insights into Effective Therapies. Sarcoma. 2017: 7429697. PMID 28592921 DOI: 10.1155/2017/7429697  0.405
2017 Miettinen MM, Antonescu CR, Fletcher CDM, Kim A, Lazar AJ, Quezado MM, Reilly KM, Stemmer-Rachamimov A, Stewart DR, Viskochil D, Widemann B, Perry A. Histopathologic Evaluation of Atypical Neurofibromatous Tumors and Their Transformation into Malignant Peripheral Nerve Sheath Tumor in Neurofibromatosis 1 Patients - A Consensus Overview. Human Pathology. PMID 28551330 DOI: 10.1016/J.Humpath.2017.05.010  0.416
2017 Reilly KM, Tuskan RG, Widemann BC. Abstract 5038: Comparison of the dose response of malignant peripheral nerve sheath tumor in vitro growth inhibition of 30 drugs to reported Cmax values Cancer Research. 77: 5038-5038. DOI: 10.1158/1538-7445.Am2017-5038  0.354
2016 Bradford D, Reilly KM, Widemann BC, Sandler A, Kummar S. Developing therapies for rare tumors: opportunities, challenges and progress. Expert Opinion On Orphan Drugs. 4: 93-103. PMID 32765971 DOI: 10.1517/21678707.2016.1120663  0.409
2016 Karmakar S, Reilly KM. The role of the immune system in neurofibromatosis type 1-associated nervous system tumors. Cns Oncology. PMID 28001089 DOI: 10.2217/Cns-2016-0024  0.409
2016 Pisklakova A, McKenzie B, Zemp F, Lun X, Kenchappa RS, Etame AB, Rahman MM, Reilly K, Pilon-Thomas S, McFadden G, Kurz E, Forsyth PA. M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of glioblastoma. Neuro-Oncology. PMID 26962017 DOI: 10.1093/Neuonc/Now006  0.383
2015 Henrich CJ, Cartner LK, Wilson JA, Fuller RW, Rizzo AE, Reilly KM, McMahon JB, Gustafson KR. Deguelins, Natural Product Modulators of NF1-Defective Astrocytoma Cell Growth Identified by High-Throughput Screening of Partially Purified Natural Product Extracts. Journal of Natural Products. PMID 26467198 DOI: 10.1021/Acs.Jnatprod.5B00753  0.303
2015 Hirbe AC, Dahiya S, Miller CA, Li T, Fulton RS, Zhang X, McDonald S, DeSchryver K, Duncavage EJ, Walrath J, Reilly KM, Abel HJ, Pekmezci M, Perry A, Ley TJ, et al. Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25925892 DOI: 10.1158/1078-0432.Ccr-14-3049  0.415
2015 Warrington NM, Sun T, Luo J, McKinstry RC, Parkin PC, Ganzhorn S, Spoljaric D, Albers AC, Merkelson A, Stewart DR, Stevenson DA, Viskochil D, Druley TE, Forys JT, Reilly KM, et al. The cyclic AMP pathway is a sex-specific modifier of glioma risk in type I neurofibromatosis patients. Cancer Research. 75: 16-21. PMID 25381154 DOI: 10.1158/0008-5472.Can-14-1891  0.364
2015 Reilly KM, Tuskan RG, Widemann BC. Abstract 4199: Developing therapies for rare tumors: Using mouse models of malignant peripheral nerve sheath tumors to complement rare human samples in drug screens Cancer Research. 75: 4199-4199. DOI: 10.1158/1538-7445.Am2015-4199  0.426
2014 Zemp FJ, McKenzie BA, Lun X, Reilly KM, McFadden G, Yong VW, Forsyth PA. Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus. Cancer Research. 74: 7260-73. PMID 25336188 DOI: 10.1158/0008-5472.Can-14-0876  0.389
2014 Devkota KP, Wilson JA, Henrich CJ, McMahon JB, Reilly KM, Beutler JA. Compounds from Simarouba berteroana which inhibit proliferation of NF1-defective cancer cells. Phytochemistry Letters. 7: 42-45. PMID 24443661 DOI: 10.1016/J.Phytol.2013.09.007  0.325
2014 Lee M, Reilly K. Pm-10Cdca7L Functions As A Male-Specific Oncogene In Astrocytoma. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou268.10  0.35
2013 Zemp FJ, McKenzie BA, Lun X, Maxwell L, Reilly KM, McFadden G, Yong VW, Forsyth PA. Resistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent of anti-viral type-I interferon. Plos One. 8: e65801. PMID 23762429 DOI: 10.1371/Journal.Pone.0065801  0.328
2013 Reilly KM. Extending the convergence of canonical WNT signaling and classic cancer pathways for treatment of malignant peripheral nerve sheath tumors. Cancer Discovery. 3: 610-2. PMID 23749527 DOI: 10.1158/2159-8290.CD-13-0192  0.356
2013 Devkota KP, Wilson J, Henrich CJ, McMahon JB, Reilly KM, Beutler JA. Isobutylhydroxyamides from the pericarp of Nepalese Zanthoxylum armatum inhibit NF1-defective tumor cell line growth. Journal of Natural Products. 76: 59-63. PMID 23268719 DOI: 10.1021/Np300696G  0.374
2013 Turbyville T, Brafman A, Chen D, Romanchuck K, Beutler J, Reilly K, Lockett S. Abstract 3429: Coordination of cell cycle repression and reduced cytoskeletal tension by the small molecule natural product, Schweinfurthin A. Cancer Research. 73: 3429-3429. DOI: 10.1158/1538-7445.Am2013-3429  0.433
2013 Reilly KM, Lee M, Schaick JA. Abstract 3005: Cdca7l is a sex-specific modifier of astrocytoma and glioblastoma. Cancer Research. 73: 3005-3005. DOI: 10.1158/1538-7445.Am2013-3005  0.408
2013 Lee MH, Jones G, Amlin-Van Schaick J, DiFabio C, Whitman M, Shankavarum U, Huynh T, Kim S, Pacak K, Broman KW, Reilly KM. Modifiers of Neurofibromatosis-Associated Tumors and the Potential Role for Catecholamines and Sex Differences Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 73. DOI: 10.1016/B978-0-12-800044-1.00064-7  0.301
2012 Amlin-Van Schaick JC, Kim S, DiFabio C, Lee MH, Broman KW, Reilly KM. Arlm1 is a male-specific modifier of astrocytoma resistance on mouse Chr 12. Neuro-Oncology. 14: 160-74. PMID 22234937 DOI: 10.1093/Neuonc/Nor206  0.359
2012 Amlin-Van Schaick J, Kim S, Broman KW, Reilly KM. Scram1 is a modifier of spinal cord resistance for astrocytoma on mouse Chr 5. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 277-85. PMID 22160242 DOI: 10.1007/S00335-011-9380-0  0.329
2012 Brognaro E, Ghods A, Feinstein D, Glick R, Connolly KJ, Meetze K, Boudrow A, Gyuris J, Han M, Hingtgen S, Figueiredo J, Farrar C, Farrar C, Deubgen M, Martinez-Quintanilla J, ... ... Reilly K, et al. LAB-TUMOR MODELS (IN VIVO/IN VITRO) Neuro-Oncology. 14: vi160-vi164. DOI: 10.1093/Neuonc/Nos241  0.416
2012 Castro Ruiz A, Wilson J, Henrich C, Reilly K, McMahon J, Gustafson K. Antiastrocytoma natural products that target tumor cells with defects in the tumor suppressor neurofibromin Planta Medica. 78. DOI: 10.1055/s-0032-1320719  0.316
2012 Jones GN, Reilly KM. Dissection of complex genetic and epigenetic interactions underlying nf1 cancer susceptibility using mouse models Neurofibromatosis Type 1: Molecular and Cellular Biology. 2147483647: 287-304. DOI: 10.1007/978-3-642-32864-0_19  0.3
2011 Gürsel DB, Connell-Albert YS, Tuskan RG, Anastassiadis T, Walrath JC, Hawes JJ, Amlin-Van Schaick JC, Reilly KM. Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapies. Neuro-Oncology. 13: 610-21. PMID 21636709 DOI: 10.1093/Neuonc/Nor035  0.388
2011 Huson SM, Acosta MT, Belzberg AJ, Bernards A, Chernoff J, Cichowski K, Gareth Evans D, Ferner RE, Giovannini M, Korf BR, Listernick R, North KN, Packer RJ, Parada LF, Peltonen J, ... ... Reilly KM, et al. Back to the future: proceedings from the 2010 NF Conference. American Journal of Medical Genetics. Part A. 155: 307-21. PMID 21271647 DOI: 10.1002/Ajmg.A.33804  0.419
2010 Turbyville TJ, Gürsel DB, Tuskan RG, Walrath JC, Lipschultz CA, Lockett SJ, Wiemer DF, Beutler JA, Reilly KM. Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner. Molecular Cancer Therapeutics. 9: 1234-43. PMID 20442305 DOI: 10.1158/1535-7163.Mct-09-0834  0.523
2010 Walrath JC, Hawes JJ, Van Dyke T, Reilly KM. Genetically engineered mouse models in cancer research. Advances in Cancer Research. 106: 113-64. PMID 20399958 DOI: 10.1016/S0065-230X(10)06004-5  0.424
2010 Pemov A, Park C, Reilly KM, Stewart DR. Evidence of perturbations of cell cycle and DNA repair pathways as a consequence of human and murine NF1-haploinsufficiency. Bmc Genomics. 11: 194. PMID 20307317 DOI: 10.1186/1471-2164-11-194  0.445
2010 Hawes JJ, Reilly KM. Bioluminescent approaches for measuring tumor growth in a mouse model of neurofibromatosis. Toxicologic Pathology. 38: 123-30. PMID 20176786 DOI: 10.1177/0192623309357075  0.491
2010 Banerjee S, Byrd JN, Gianino SM, Harpstrite SE, Rodriguez FJ, Tuskan RG, Reilly KM, Piwnica-Worms DR, Gutmann DH. The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo. Cancer Research. 70: 1356-66. PMID 20124472 DOI: 10.1158/0008-5472.Can-09-2178  0.489
2010 Connell-Albert Y, Gursel D, Tuskan R, Anastassiadis T, Hawes J, Schaick JV, Reilly K. Abstract 354: PI-103 and TCN as proliferative inhibitors of the RTK/PI3K/ATK signaling pathways in astrocytomas Cancer Research. 70: 354-354. DOI: 10.1158/1538-7445.Am10-354  0.373
2009 Walrath JC, Fox K, Truffer E, Gregory Alvord W, Quiñones OA, Reilly KM. Chr 19(A/J) modifies tumor resistance in a sex- and parent-of-origin-specific manner. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 214-23. PMID 19347398 DOI: 10.1007/S00335-009-9179-4  0.432
2009 Reilly KM. Brain tumor susceptibility: the role of genetic factors and uses of mouse models to unravel risk. Brain Pathology (Zurich, Switzerland). 19: 121-31. PMID 19076777 DOI: 10.1111/j.1750-3639.2008.00236.x  0.303
2009 Hawes JH, Tuskan RG, Agaki K, Reilly KM. Abstract C12: EGFR signaling controls the chromatin binding status of BMI1 through a CK2/PP1 phosphorylation/dephosphorylation pathway and affects astrocytoma proliferation and neural stem cell differentiation Cancer Research. 69: 4893-4893. DOI: 10.1158/0008-5472.Fbcr09-C12  0.396
2008 Reilly KM, Van Dyke T. It takes a (dysfunctional) village to raise a tumor. Cell. 135: 408-10. PMID 18984150 DOI: 10.1016/J.Cell.2008.10.009  0.466
2008 Hawes JJ, Nerva JD, Reilly KM. Novel dual-reporter preclinical screen for antiastrocytoma agents identifies cytostatic and cytotoxic compounds. Journal of Biomolecular Screening. 13: 795-803. PMID 18664715 DOI: 10.1177/1087057108321085  0.367
2008 Reilly KM, Rubin JB, Gilbertson RJ, Garbow JR, Roussel MF, Gutmann DH. Rethinking brain tumors: the fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop. Cancer Research. 68: 5508-11. PMID 18632599 DOI: 10.1158/0008-5472.Can-08-0703  0.471
2008 Tuskan RG, Tsang S, Sun Z, Baer J, Rozenblum E, Wu X, Munroe DJ, Reilly KM. Real-time PCR analysis of candidate imprinted genes on mouse chromosome 11 shows balanced expression from the maternal and paternal chromosomes and strain-specific variation in expression levels. Epigenetics : Official Journal of the Dna Methylation Society. 3: 43-50. PMID 18188004 DOI: 10.4161/Epi.3.1.5469  0.348
2007 Hawes JJ, Tuskan RG, Reilly KM. Nf1 expression is dependent on strain background: implications for tumor suppressor haploinsufficiency studies. Neurogenetics. 8: 121-30. PMID 17216419 DOI: 10.1007/S10048-006-0078-5  0.462
2006 Reilly KM, Broman KW, Bronson RT, Tsang S, Loisel DA, Christy ES, Sun Z, Diehl J, Munroe DJ, Tuskan RG. An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model. Cancer Research. 66: 62-8. PMID 16397217 DOI: 10.1158/0008-5472.Can-05-1480  0.473
2005 Gürsel DB, Reilly KM. Models of astrocytoma Drug Discovery Today: Disease Models. 2: 77-83. DOI: 10.1016/J.Ddmod.2005.05.003  0.357
2004 Hatano M, Kuwashima N, Tatsumi T, Dusak JE, Nishimura F, Reilly KM, Storkus WJ, Okada H. Vaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumors. Journal of Translational Medicine. 2: 40. PMID 15563374 DOI: 10.1186/1479-5876-2-40  0.353
2004 Reilly KM, Tuskan RG, Christy E, Loisel DA, Ledger J, Bronson RT, Smith CD, Tsang S, Munroe DJ, Jacks T. Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects. Proceedings of the National Academy of Sciences of the United States of America. 101: 13008-13. PMID 15319471 DOI: 10.1073/Pnas.0401236101  0.426
2004 Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, ... ... Reilly KM, et al. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Research. 64: 3718-24. PMID 15150133 DOI: 10.1158/0008-5472.Can-03-4079  0.442
2002 Weiss WA, Israel M, Cobbs C, Holland E, James CD, Louis DN, Marks C, McClatchey AI, Roberts T, Van Dyke T, Wetmore C, Chiu IM, Giovannini M, Guha A, Higgins RJ, ... ... Reilly K, et al. Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene. 21: 7453-63. PMID 12386807 DOI: 10.1038/Sj.Onc.1205936  0.482
2001 Reilly KM, Jacks T. Genetically engineered mouse models of astrocytoma: GEMs in the rough? Seminars in Cancer Biology. 11: 177-91. PMID 11407943 DOI: 10.1006/Scbi.2000.0375  0.375
2001 Bajenaru ML, Donahoe J, Corral T, Reilly KM, Brophy S, Pellicer A, Gutmann DH. Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes. Glia. 33: 314-23. PMID 11246230 DOI: 10.1002/1098-1136(20010315)33:4<314::Aid-Glia1030>3.0.Co;2-Q  0.374
2000 Reilly KM, Loisel DA, Bronson RT, McLaughlin ME, Jacks T. Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects. Nature Genetics. 26: 109-13. PMID 10973261 DOI: 10.1038/79075  0.402
1999 Cichowski K, Shih TS, Schmitt E, Santiago S, Reilly K, McLaughlin ME, Bronson RT, Jacks T. Mouse models of tumor development in neurofibromatosis type 1. Science (New York, N.Y.). 286: 2172-6. PMID 10591652 DOI: 10.1126/Science.286.5447.2172  0.487
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