Jodi A. Flaws - Publications

Affiliations: 
Comparative Biosciences University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Toxicology, Endocrinology Biology, Molecular Biology

207 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Safar AM, Santacruz-Márquez R, Laws MJ, Meling DD, Liu Z, Kumar TR, Nowak RA, Raetzman LT, Flaws JA. Dietary exposure to an environmentally relevant phthalate mixture alters follicle dynamics, hormone levels, ovarian gene expression, and pituitary gene expression in female mice. Reproductive Toxicology (Elmsford, N.Y.). 122: 108489. PMID 37839492 DOI: 10.1016/j.reprotox.2023.108489  0.314
2023 Santacruz-Márquez R, Safar AM, Laws MJ, Meling DD, Liu Z, Kumar TR, Nowak RA, Raetzman LT, Flaws JA. The effects of short-term and long-term phthalate exposures on ovarian follicle growth dynamics and hormone levels in female mice. Biology of Reproduction. PMID 37812459 DOI: 10.1093/biolre/ioad137  0.303
2023 Weis KE, Thompson LM, Streifer M, Guardado I, Flaws JA, Gore AC, Raetzman LT. Pre- and Postnatal Developmental Exposure to the Polychlorinated Biphenyl Mixture Aroclor 1221 Alters Female Rat Pituitary Gonadotropins and Estrogen Receptor Alpha Levels. Reproductive Toxicology (Elmsford, N.Y.). 108388. PMID 37127253 DOI: 10.1016/j.reprotox.2023.108388  0.307
2022 Furth PA, Wang W, Kang K, Rooney BL, Keegan G, Muralidaran V, Zou X, Flaws JA. Esr1 but Not CYP19A1 Overexpression in Mammary Epithelial Cells during Reproductive Senescence Induces Pregnancy-Like Proliferative Mammary Disease Responsive to Anti-Hormonals. The American Journal of Pathology. 193: 84-102. PMID 36464512 DOI: 10.1016/j.ajpath.2022.09.007  0.303
2022 Yang M, Lee Y, Gao L, Chiu K, Meling DD, Flaws JA, Warner GR. Perfluorooctanoic acid (PFOA) disrupts ovarian steroidogenesis and folliculogenesis in adult mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 35104888 DOI: 10.1093/toxsci/kfac005  0.317
2021 Maurice C, Dalvai M, Lambrot R, Deschênes A, Scott-Boyer MP, McGraw S, Chan D, Côté N, Ziv-Gal A, Flaws JA, Droit A, Trasler J, Kimmins S, Bailey JL. Early-Life Exposure to Environmental Contaminants Perturbs the Sperm Epigenome and Induces Negative Pregnancy Outcomes for Three Generations via the Paternal Lineage. Epigenomes. 5. PMID 34968297 DOI: 10.3390/epigenomes5020010  0.738
2021 Ge X, Weis K, Flaws J, Raetzman L. Prenatal exposure to the phthalate DEHP impacts reproduction-related gene expression in the pituitary. Reproductive Toxicology (Elmsford, N.Y.). 108: 18-27. PMID 34954075 DOI: 10.1016/j.reprotox.2021.12.008  0.335
2021 Gonzalez RVL, Weis KE, Gonsioroski AV, Flaws JA, Raetzman LT. Iodoacetic acid, a water disinfection byproduct, disrupts hypothalamic and pituitary reproductive regulatory factors and induces toxicity in the female pituitary. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 34453833 DOI: 10.1093/toxsci/kfab106  0.328
2021 Gonsioroski A, Meling DD, Gao L, Plewa MJ, Flaws JA. Iodoacetic acid affects Estrous Cyclicity, ovarian gene expression, and hormone levels in mice. Biology of Reproduction. PMID 34086879 DOI: 10.1093/biolre/ioab108  0.343
2020 Heindel JJ, Belcher S, Flaws JA, Prins GS, Ho SM, Mao J, Patisaul HB, Ricke W, Rosenfeld CS, Soto AM, Vom Saal FS, Zoeller RT. Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies. Reproductive Toxicology (Elmsford, N.Y.). PMID 32682780 DOI: 10.1016/J.Reprotox.2020.05.014  0.302
2020 Wen Y, Rattan S, Flaws JA, Irudayaraj J. Multi and transgenerational epigenetic effects of di-(2-ethylhexyl) phthalate (DEHP) in liver. Toxicology and Applied Pharmacology. 115123. PMID 32628958 DOI: 10.1016/J.Taap.2020.115123  0.318
2020 Sarmento IV, Merlo E, Meyrelles SS, Vasquez EC, Warner GR, Gonsioroski A, De La Torre K, Meling DD, Flaws JA, Graceli JB. Subchronic and low dose of tributyltin exposure leads to reduced ovarian reserve, reduced uterine gland number, and other reproductive irregularities in female mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32239163 DOI: 10.1093/Toxsci/Kfaa045  0.423
2020 Barakat R, Lin PC, Park CJ, Zeineldin M, Zhou S, Rattan S, Brehm E, Flaws JA, Ko CJ. Germline-dependent transmission of male reproductive traits induced by an endocrine disruptor, di-2-ethylhexyl phthalate, in future generations. Scientific Reports. 10: 5705. PMID 32235866 DOI: 10.1038/S41598-020-62584-W  0.307
2020 Chiang C, Lewis LR, Borkowski G, Flaws JA. Exposure to di(2-ethylhexyl) phthalate and diisononyl phthalate during adulthood disrupts hormones and ovarian folliculogenesis throughout the prime reproductive life of the mouse. Toxicology and Applied Pharmacology. 114952. PMID 32165126 DOI: 10.1016/J.Taap.2020.114952  0.385
2020 Li K, Liszka M, Zhou C, Brehm E, Flaws JA, Nowak RA. Prenatal Exposure to a Phthalate Mixture Leads to Multigenerational and Transgenerational Effects on Uterine Morphology and Function in Mice. Reproductive Toxicology (Elmsford, N.Y.). PMID 32126281 DOI: 10.1016/J.Reprotox.2020.02.012  0.359
2020 Chiang C, Lewis LR, Borkowski G, Flaws JA. Late-Life Consequences of Short-Term Exposure to Di(2-ethylhexyl) Phthalate and Diisononyl Phthalate During Adulthood in Female Mice. Reproductive Toxicology (Elmsford, N.Y.). PMID 31904422 DOI: 10.1016/J.Reprotox.2019.12.006  0.371
2020 Gonzalez R, Weis KE, Gonsioroski AV, Flaws JA, Raetzman LT. SUN-241 Adult Exposure to Iodoacetic Acid Leads to Abnormal Expression of Key Genes Related to Hypothalamic and Pituitary Control of Reproductive Function Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1083  0.406
2019 Meling DD, Warner GR, Szumski JR, Gao L, Gonsioroski AV, Rattan S, Flaws JA. The effects of a phthalate metabolite mixture on antral follicle growth and sex steroid synthesis in mice. Toxicology and Applied Pharmacology. 114875. PMID 31884101 DOI: 10.1016/J.Taap.2019.114875  0.45
2019 Warner GR, Mourikes VE, Neff AM, Brehm E, Flaws JA. Mechanisms of action of agrochemicals acting as endocrine disrupting chemicals. Molecular and Cellular Endocrinology. 502: 110680. PMID 31838026 DOI: 10.1016/J.Mce.2019.110680  0.346
2019 Gonsioroski A, Meling DD, Gao L, Plewa MJ, Flaws JA. Iodoacetic Acid Inhibits Follicle Growth and Alters Expression of Genes that Regulate Apoptosis, the Cell Cycle, Estrogen Receptors, and Ovarian Steroidogenesis in Mouse Ovarian Follicles. Reproductive Toxicology (Elmsford, N.Y.). PMID 31693920 DOI: 10.1016/J.Reprotox.2019.10.005  0.454
2019 Rattan S, Beers HK, Kannan A, Ramakrishnan A, Brehm E, Bagchi I, Irudayaraj JMK, Flaws JA. Prenatal and ancestral exposure to di(2-ethylhexyl) phthalate alters gene expression and DNA methylation in mouse ovaries. Toxicology and Applied Pharmacology. 114629. PMID 31211961 DOI: 10.1016/J.Taap.2019.114629  0.381
2019 Scarano WR, Bedrat A, Alonso-Costa LG, Aquino AM, Fantinatti B, Justulin LA, Barbisan LF, Freire PP, Flaws JA, Bernardo L. Exposure to an environmentally relevant phthalate mixture during prostate development induces microRNA upregulation and transcriptome modulation in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31199487 DOI: 10.1093/Toxsci/Kfz141  0.316
2019 Wolstenholme JT, Drobná Z, Henriksen AD, Goldsby JA, Stevenson R, Irvin JW, Flaws JA, Rissman EF. Transgenerational Bisphenol A causes deficits in social recognition and alters post-synaptic density genes in mice. Endocrinology. PMID 31188430 DOI: 10.1210/En.2019-00196  0.334
2019 Rattan S, Flaws JA. The epigenetic impacts of endocrine disruptors on female reproduction across generations†. Biology of Reproduction. PMID 31077281 DOI: 10.1093/Biolre/Ioz081  0.365
2019 Damdimopoulou P, Chiang C, Flaws J. Retinoic acid signaling in ovarian folliculogenesis and steroidogenesis. Reproductive Toxicology (Elmsford, N.Y.). PMID 31059772 DOI: 10.1016/J.Reprotox.2019.04.007  0.338
2019 Hatcher KM, Willing J, Chiang C, Rattan S, Flaws JA, Mahoney MM. Exposure to di-(2-ethylhexyl) phthalate transgenerationally alters anxiety-like behavior and amygdala gene expression in adult male and female mice. Physiology & Behavior. PMID 31022410 DOI: 10.1016/J.Physbeh.2019.04.018  0.369
2019 Brehm E, Flaws JA. Transgenerational effects of endocrine disrupting chemicals on male and female reproduction. Endocrinology. PMID 30998239 DOI: 10.1210/En.2019-00034  0.333
2019 Neff AM, Blanco SC, Flaws JA, Bagchi IC, Bagchi MK. Chronic Exposure of Mice to Bisphenol-A Alters Uterine FGF Signaling and Leads to Aberrant Epithelial Proliferation. Endocrinology. PMID 30892605 DOI: 10.1210/En.2018-00872  0.412
2019 Warner GR, Li Z, Houde ML, Atkinson CE, Meling DD, Chiang C, Flaws JA. Ovarian Metabolism of an Environmentally Relevant Phthalate Mixture. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30768133 DOI: 10.1093/Toxsci/Kfz047  0.331
2019 Chiang C, Flaws JA. Sub-Chronic Exposure to Di(2-ethylhexyl) Phthalate and Diisononyl Phthalate During Adulthood Has Immediate and Long-Term Reproductive Consequences in Female Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30649530 DOI: 10.1093/Toxsci/Kfz013  0.324
2019 Chiang C, Gallicchio L, Zacur H, Miller S, Flaws JA, Smith RL. Hormone variability and hot flash experience: Results from the midlife women's health study. Maturitas. 119: 1-7. PMID 30502745 DOI: 10.1016/J.Maturitas.2018.10.007  0.326
2019 Tannenbaum LV, Gao L, Flaws JA. Ovarian follicle resilience in mice orally dosed with methoxychlor: Are reproductive impacts possible in mammals as ecological receptors? Ecological Indicators. 106: 105502. DOI: 10.1016/J.Ecolind.2019.105502  0.389
2018 Barakat R, Lin PC, Park CJ, Best-Popescu C, Bakry HH, Abosalem ME, Abdelaleem NM, Flaws JA, Ko C. Corrigendum to "Prenatal Exposure to DEHP Induces Neuronal Degeneration and Neurobehavioral Abnormalities in Adult Male Mice". Toxicological Sciences : An Official Journal of the Society of Toxicology. 164: 645. PMID 30060034 DOI: 10.1093/Toxsci/Kfy165  0.316
2018 Kundu P, Patel S, Meling DD, Deal K, Gao L, Helferich WG, Flaws JA. The Effects of Dietary Levels of Genistein on Ovarian Follicle Number and Gene Expression. Reproductive Toxicology (Elmsford, N.Y.). PMID 30056207 DOI: 10.1016/J.Reprotox.2018.07.085  0.371
2018 Li Q, Lawrence CR, Nowak RA, Flaws JA, Bagchi MK, Bagchi IC. Bisphenol A and Phthalates Modulate Peritoneal Macrophage Function in Female Mice Involving SYMD2-H3K36 Dimethylation. Endocrinology. 159: 2216-2228. PMID 29718165 DOI: 10.1210/En.2017-03000  0.352
2018 Barakat R, Lin PC, Park CJ, Best-Popescu C, Bakery HH, Abosalum ME, Abdelaleem NM, Flaws JA, Ko C. Prenatal Exposure to DEHP Induces Neuronal Degeneration and Neurobehavioral Abnormalities in Adult Male Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29688563 DOI: 10.1093/Toxsci/Kfy103  0.366
2018 Rattan S, Brehm E, Gao L, Flaws JA. Di(2-ethylhexyl) phthalate exposure during prenatal development causes adverse transgenerational effects on female fertility in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29471507 DOI: 10.1093/Toxsci/Kfy042  0.325
2018 Richardson KA, Hannon PR, Johnson-Walker YJ, Myint MS, Flaws JA, Nowak RA. Di (2-ethylhexyl) phthalate (DEHP) alters proliferation and uterine gland numbers in the uteri of adult exposed mice. Reproductive Toxicology (Elmsford, N.Y.). PMID 29458081 DOI: 10.1016/J.Reprotox.2018.01.006  0.318
2018 Brehm E, Rattan S, Gao L, Flaws JA. Prenatal Exposure to Di(2-Ethylhexyl) Phthalate Causes Long-Term Transgenerational Effects on Female Reproduction in Mice. Endocrinology. 159: 795-809. PMID 29228129 DOI: 10.1210/En.2017-03004  0.306
2017 Ziv-Gal A, Smith RL, Gallicchio L, Miller SR, Zacur HA, Flaws JA. The Midlife Women's Health Study - a study protocol of a longitudinal prospective study on predictors of menopausal hot flashes. Women's Midlife Health. 3: 4. PMID 30766705 DOI: 10.1186/S40695-017-0024-8  0.744
2017 Rattan S, Brehm E, Gao L, Niermann S, Flaws JA. Prenatal exposure to di(2-ethylhexyl) phthalate (DEHP) disrupts ovarian function in a transgenerational manner in female mice. Biology of Reproduction. PMID 29165555 DOI: 10.1093/Biolre/Iox154  0.363
2017 Eckstrum KS, Edwards W, Banerjee A, Wang W, Flaws JA, Katzenellenbogen JA, Kim SH, Raetzman LT. Effects of exposure to the endocrine disrupting chemical bisphenol A during critical windows of murine pituitary development. Endocrinology. PMID 29092056 DOI: 10.1210/En.2017-00565  0.417
2017 Patel S, Hartman JA, Helferich WG, Flaws JA. Preconception exposure to dietary levels of genistein affects female reproductive outcomes. Reproductive Toxicology (Elmsford, N.Y.). PMID 28970133 DOI: 10.1016/J.Reprotox.2017.09.014  0.402
2017 Mahalingam S, Ther L, Gao L, Wang W, Ziv-Gal A, Flaws JA. The effects of in utero bisphenol A exposure on ovarian follicle numbers and steroidogenesis in the F1 and F2 generations of mice. Reproductive Toxicology (Elmsford, N.Y.). PMID 28970132 DOI: 10.1016/J.Reprotox.2017.09.013  0.77
2017 Olson MR, Su R, Flaws JA, Fazleabas AT. Bisphenol A Impairs Decidualization of Human Uterine Stromal Fibroblasts. Reproductive Toxicology (Elmsford, N.Y.). PMID 28729173 DOI: 10.1016/J.Reprotox.2017.07.008  0.401
2017 Chiang C, Mahalingam S, Flaws JA. Environmental Contaminants Affecting Fertility and Somatic Health. Seminars in Reproductive Medicine. 35: 241-249. PMID 28658707 DOI: 10.1055/S-0037-1603569  0.316
2017 Zhou C, Gao L, Flaws JA. Exposure to an environmentally relevant phthalate mixture causes transgenerational effects on female reproduction in mice. Endocrinology. PMID 28368545 DOI: 10.1210/En.2017-00100  0.327
2017 Rattan S, Zhou C, Chiang C, Mahalingam S, Brehm E, Flaws J. Exposure to endocrine disruptors during adulthood: consequences for female fertility. The Journal of Endocrinology. PMID 28356401 DOI: 10.1530/Joe-17-0023  0.37
2017 Patel S, Brehm E, Gao L, Rattan S, Ziv-Gal A, Flaws JA. Bisphenol A Exposure, Ovarian Follicle Numbers, and Female Sex Steroid Hormone Levels: Results from a CLARITY-BPA Study. Endocrinology. PMID 28324068 DOI: 10.1210/En.2016-1887  0.782
2017 Zhou C, Gao L, Flaws JA. Prenatal exposure to an environmentally relevant phthalate mixture disrupts reproduction in F1 female mice. Toxicology and Applied Pharmacology. PMID 28126412 DOI: 10.1016/J.Taap.2017.01.010  0.394
2017 Barakat R, Lin PP, Rattan S, Brehm E, Canisso IF, Abosalum ME, Flaws JA, Hess R, Ko C. Prenatal exposure to DEHP induces premature reproductive senescence in male mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28082598 DOI: 10.1093/Toxsci/Kfw248  0.381
2016 Zhou C, Flaws JA. Effects of an environmentally relevant phthalate mixture on cultured mouse antral follicles. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28013214 DOI: 10.1093/Toxsci/Kfw245  0.459
2016 Mahalingam S, Gao L, Eisner J, Helferich W, Flaws JA. Effects of isoliquiritigenin on ovarian antral follicle growth and steroidogenesis. Reproductive Toxicology (Elmsford, N.Y.). PMID 27773742 DOI: 10.1016/J.Reprotox.2016.10.004  0.455
2016 Gong P, Madak-Erdogan Z, Flaws JA, Shapiro DJ, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells. Molecular and Cellular Endocrinology. PMID 27543265 DOI: 10.1016/J.Mce.2016.08.025  0.367
2016 Ziv-Gal A, Flaws JA. Evidence for bisphenol A-induced female infertility: review (2007-2016). Fertility and Sterility. PMID 27417731 DOI: 10.1016/J.Fertnstert.2016.06.027  0.761
2016 Jeong CH, Gao L, Dettro T, Wagner ED, Ricke WA, Plewa MJ, Flaws JA. Monohaloacetic acid drinking water disinfection by-products inhibit follicle growth and steroidogenesis in mouse ovarian antral follicles in vitro. Reproductive Toxicology (Elmsford, N.Y.). PMID 27151372 DOI: 10.1016/J.Reprotox.2016.04.028  0.372
2016 Li Q, Davila J, Kannan A, Flaws JA, Bagchi MK, Bagchi IC. Chronic exposure to Bisphenol A affects uterine function during early pregnancy in mice. Endocrinology. en20152031. PMID 27022677 DOI: 10.1210/En.2015-2031  0.393
2016 Mahalingam S, Gao L, Gonnering M, Helferich W, Flaws JA. Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles in vitro. Toxicology and Applied Pharmacology. 295: 47-55. PMID 26876617 DOI: 10.1016/J.Taap.2016.02.009  0.444
2016 Ziv-Gal A, Gallicchio L, Chiang C, Ther SN, Miller SR, Zacur HA, Dills RL, Flaws JA. Phthalate metabolite levels and menopausal hot flashes in midlife women. Reproductive Toxicology (Elmsford, N.Y.). 60: 76-81. PMID 26867866 DOI: 10.1016/J.Reprotox.2016.02.001  0.743
2016 Patel S, Peretz J, Pan YX, Helferich WG, Flaws JA. Genistein exposure inhibits growth and alters steroidogenesis in adult mouse antral follicles. Toxicology and Applied Pharmacology. 293: 53-62. PMID 26792615 DOI: 10.1016/J.Taap.2015.12.026  0.789
2016 Hannon PR, Niermann S, Flaws JA. Acute Exposure to Di(2-Ethylhexyl) Phthalate in Adulthood Causes Adverse Reproductive Outcomes Later in Life and Accelerates Reproductive Aging in Female Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 150: 97-108. PMID 26678702 DOI: 10.1093/Toxsci/Kfv317  0.399
2016 Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, Toppari J, Zoeller RT. Executive Summary to EDC-2: The Endocrine Society's second Scientific Statement on endocrine-disrupting chemicals Endocrine Reviews. 36: 593-602. DOI: 10.1210/Er.2015-1093  0.336
2016 Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, Toppari J, Zoeller RT. EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals Endocrine Reviews. 36: 1-150. DOI: 10.1210/Er.2015-1010  0.338
2015 Berger A, Ziv-Gal A, Cudiamat J, Wang W, Zhou C, Flaws JA. The effects of in utero bisphenol A exposure on the ovaries in multiple generations of mice. Reproductive Toxicology (Elmsford, N.Y.). PMID 26746108 DOI: 10.1016/J.Reprotox.2015.12.004  0.759
2015 Tannenbaum LV, Flaws JA. Exposure Duration-Dependent Ovarian Recovery in Methoxychlor-Treated Mice. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 104: 238-43. PMID 26551443 DOI: 10.1002/Bdrb.21164  0.363
2015 Patel S, Zhou C, Rattan S, Flaws JA. Effects of Endocrine-Disrupting Chemicals on the Ovary. Biology of Reproduction. 93: 20. PMID 26063868 DOI: 10.1095/Biolreprod.115.130336  0.38
2015 Zhou C, Wang W, Peretz J, Flaws JA. Bisphenol A exposure inhibits germ cell nest breakdown by reducing apoptosis in cultured neonatal mouse ovaries. Reproductive Toxicology (Elmsford, N.Y.). PMID 26049153 DOI: 10.1016/J.Reprotox.2015.05.012  0.76
2015 Hannon PR, Brannick KE, Wang W, Flaws JA. Mono(2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles. Biology of Reproduction. 92: 120. PMID 25810477 DOI: 10.1095/Biolreprod.115.129148  0.429
2015 Ziv-Gal A, Wang W, Zhou C, Flaws JA. The effects of in utero bisphenol A exposure on reproductive capacity in several generations of mice. Toxicology and Applied Pharmacology. 284: 354-62. PMID 25771130 DOI: 10.1016/J.Taap.2015.03.003  0.753
2015 Niermann S, Rattan S, Brehm E, Flaws JA. Prenatal exposure to di-(2-ethylhexyl) phthalate (DEHP) affects reproductive outcomes in female mice. Reproductive Toxicology (Elmsford, N.Y.). 53: 23-32. PMID 25765777 DOI: 10.1016/J.Reprotox.2015.02.013  0.366
2015 Strakovsky RS, Wang H, Engeseth NJ, Flaws JA, Helferich WG, Pan YX, Lezmi S. Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis. Toxicology and Applied Pharmacology. 284: 101-12. PMID 25748669 DOI: 10.1016/J.Taap.2015.02.021  0.308
2015 Hannon PR, Brannick KE, Wang W, Gupta RK, Flaws JA. Di(2-ethylhexyl) phthalate inhibits antral follicle growth, induces atresia, and inhibits steroid hormone production in cultured mouse antral follicles. Toxicology and Applied Pharmacology. 284: 42-53. PMID 25701202 DOI: 10.1016/J.Taap.2015.02.010  0.447
2015 Hannon PR, Flaws JA. The effects of phthalates on the ovary. Frontiers in Endocrinology. 6: 8. PMID 25699018 DOI: 10.3389/Fendo.2015.00008  0.391
2015 Ziv-Gal A, Gao L, Karman BN, Flaws JA. In vitro re-expression of the aryl hydrocarbon receptor (Ahr) in cultured Ahr-deficient mouse antral follicles partially restores the phenotype to that of cultured wild-type mouse follicles. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 329-36. PMID 25500125 DOI: 10.1016/J.Tiv.2014.11.011  0.807
2015 Montasser ME, Ziv-Gal A, Brown JP, Flaws JA, Merchenthaler I. A potentially functional variant in the serotonin transporter gene is associated with premenopausal and perimenopausal hot flashes. Menopause (New York, N.Y.). 22: 108-13. PMID 25026114 DOI: 10.1097/Gme.0000000000000291  0.715
2014 Peretz J, Vrooman L, Ricke WA, Hunt PA, Ehrlich S, Hauser R, Padmanabhan V, Taylor HS, Swan SH, VandeVoort CA, Flaws JA. Bisphenol a and reproductive health: update of experimental and human evidence, 2007-2013. Environmental Health Perspectives. 122: 775-86. PMID 24896072 DOI: 10.1289/Ehp.1307728  0.745
2014 Hannon PR, Peretz J, Flaws JA. Daily exposure to Di(2-ethylhexyl) phthalate alters estrous cyclicity and accelerates primordial follicle recruitment potentially via dysregulation of the phosphatidylinositol 3-kinase signaling pathway in adult mice. Biology of Reproduction. 90: 136. PMID 24804967 DOI: 10.1095/Biolreprod.114.119032  0.755
2014 Wang W, Hafner KS, Flaws JA. In utero bisphenol A exposure disrupts germ cell nest breakdown and reduces fertility with age in the mouse. Toxicology and Applied Pharmacology. 276: 157-64. PMID 24576723 DOI: 10.1016/J.Taap.2014.02.009  0.395
2014 Craig ZR, Singh J, Gupta RK, Flaws JA. Co-treatment of mouse antral follicles with 17β-estradiol interferes with mono-2-ethylhexyl phthalate (MEHP)-induced atresia and altered apoptosis gene expression. Reproductive Toxicology (Elmsford, N.Y.). 45: 45-51. PMID 24412242 DOI: 10.1016/J.Reprotox.2014.01.002  0.349
2014 Strakovsky RS, Lezmi S, Flaws JA, Schantz SL, Pan YX, Helferich WG. Genistein exposure during the early postnatal period favors the development of obesity in female, but not male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 138: 161-74. PMID 24361872 DOI: 10.1093/Toxsci/Kft331  0.342
2013 Peretz J, Neese SL, Flaws JA. Mouse strain does not influence the overall effects of bisphenol a-induced toxicity in adult antral follicles. Biology of Reproduction. 89: 108. PMID 24025742 DOI: 10.1095/Biolreprod.113.111864  0.763
2013 Craig ZR, Hannon PR, Flaws JA. Pregnenolone co-treatment partially restores steroidogenesis, but does not prevent growth inhibition and increased atresia in mouse ovarian antral follicles treated with mono-hydroxy methoxychlor. Toxicology and Applied Pharmacology. 272: 780-6. PMID 23948739 DOI: 10.1016/J.Taap.2013.08.002  0.425
2013 Ziv-Gal A, Craig ZR, Wang W, Flaws JA. Bisphenol A inhibits cultured mouse ovarian follicle growth partially via the aryl hydrocarbon receptor signaling pathway. Reproductive Toxicology (Elmsford, N.Y.). 42: 58-67. PMID 23928317 DOI: 10.1016/J.Reprotox.2013.07.022  0.79
2013 Ehrlich S, Williams PL, Hauser R, Missmer SA, Peretz J, Calafat AM, Flaws JA. Urinary bisphenol A concentrations and cytochrome P450 19 A1 (Cyp19) gene expression in ovarian granulosa cells: an in vivo human study. Reproductive Toxicology (Elmsford, N.Y.). 42: 18-23. PMID 23850856 DOI: 10.1016/J.Reprotox.2013.06.071  0.74
2013 Ziv-Gal A, Flaws JA, Mahoney MM, Miller SR, Zacur HA, Gallicchio L. Genetic polymorphisms in the aryl hydrocarbon receptor-signaling pathway and sleep disturbances in middle-aged women. Sleep Medicine. 14: 883-7. PMID 23768840 DOI: 10.1016/J.Sleep.2013.04.007  0.728
2013 Peretz J, Flaws JA. Bisphenol A down-regulates rate-limiting Cyp11a1 to acutely inhibit steroidogenesis in cultured mouse antral follicles. Toxicology and Applied Pharmacology. 271: 249-56. PMID 23707772 DOI: 10.1016/J.Taap.2013.04.028  0.759
2013 Hernández-Ochoa I, Gao L, Peretz J, Basavarajappa MS, Bunting SL, Karman BN, Paulose T, Flaws JA. Follicle-stimulating hormone responsiveness in antral follicles from aryl hydrocarbon receptor knockout mice. Reproductive Biology and Endocrinology : Rb&E. 11: 26. PMID 23548098 DOI: 10.1186/1477-7827-11-26  0.788
2013 Craig ZR, Hannon PR, Wang W, Ziv-Gal A, Flaws JA. Di-n-butyl phthalate disrupts the expression of genes involved in cell cycle and apoptotic pathways in mouse ovarian antral follicles. Biology of Reproduction. 88: 23. PMID 23242528 DOI: 10.1095/Biolreprod.112.105122  0.781
2012 Wang W, Craig ZR, Basavarajappa MS, Hafner KS, Flaws JA. Mono-(2-ethylhexyl) phthalate induces oxidative stress and inhibits growth of mouse ovarian antral follicles. Biology of Reproduction. 87: 152. PMID 23077170 DOI: 10.1095/Biolreprod.112.102467  0.758
2012 Ehrlich S, Williams PL, Missmer SA, Flaws JA, Ye X, Calafat AM, Petrozza JC, Wright D, Hauser R. Urinary bisphenol A concentrations and early reproductive health outcomes among women undergoing IVF. Human Reproduction (Oxford, England). 27: 3583-92. PMID 23014629 DOI: 10.1093/Humrep/Des328  0.322
2012 Basavarajappa MS, Karman BN, Wang W, Gupta RK, Flaws JA. Methoxychlor induces atresia by altering Bcl2 factors and inducing caspase activity in mouse ovarian antral follicles in vitro. Reproductive Toxicology (Elmsford, N.Y.). 34: 545-51. PMID 23000595 DOI: 10.1016/J.Reprotox.2012.08.007  0.775
2012 Karman BN, Basavarajappa MS, Hannon P, Flaws JA. Dioxin exposure reduces the steroidogenic capacity of mouse antral follicles mainly at the level of HSD17B1 without altering atresia. Toxicology and Applied Pharmacology. 264: 1-12. PMID 22889882 DOI: 10.1016/J.Taap.2012.07.031  0.797
2012 Brannick KE, Craig ZR, Himes AD, Peretz JR, Wang W, Flaws JA, Raetzman LT. Prenatal exposure to low doses of bisphenol A increases pituitary proliferation and gonadotroph number in female mice offspring at birth. Biology of Reproduction. 87: 82. PMID 22875908 DOI: 10.1095/Biolreprod.112.100636  0.783
2012 Ziv-Gal A, Gallicchio L, Miller SR, Zacur HA, Flaws JA. Genetic polymorphisms in the aryl hydrocarbon receptor signaling pathway as potential risk factors of menopausal hot flashes. American Journal of Obstetrics and Gynecology. 207: 202.e9-202.e18. PMID 22840970 DOI: 10.1016/J.Ajog.2012.05.019  0.741
2012 Peretz J, Craig ZR, Flaws JA. Bisphenol A inhibits follicle growth and induces atresia in cultured mouse antral follicles independently of the genomic estrogenic pathway. Biology of Reproduction. 87: 63. PMID 22743301 DOI: 10.1095/Biolreprod.112.101899  0.795
2012 Paulose T, Tannenbaum LV, Borgeest C, Flaws JA. Methoxychlor-induced ovarian follicle toxicity in mice: dose and exposure duration-dependent effects. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 95: 219-24. PMID 22495784 DOI: 10.1002/Bdrb.21007  0.797
2012 Basavarajappa MS, Hernández-Ochoa I, Wang W, Flaws JA. Methoxychlor inhibits growth and induces atresia through the aryl hydrocarbon receptor pathway in mouse ovarian antral follicles. Reproductive Toxicology (Elmsford, N.Y.). 34: 16-21. PMID 22484361 DOI: 10.1016/J.Reprotox.2012.03.007  0.766
2012 Karman BN, Basavarajappa MS, Craig ZR, Flaws JA. 2,3,7,8-Tetrachlorodibenzo-p-dioxin activates the aryl hydrocarbon receptor and alters sex steroid hormone secretion without affecting growth of mouse antral follicles in vitro. Toxicology and Applied Pharmacology. 261: 88-96. PMID 22483799 DOI: 10.1016/J.Taap.2012.03.015  0.823
2012 Hoffman GE, Le WW, Entezam A, Otsuka N, Tong ZB, Nelson L, Flaws JA, McDonald JH, Jafar S, Usdin K. Ovarian abnormalities in a mouse model of fragile X primary ovarian insufficiency. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 60: 439-56. PMID 22470123 DOI: 10.1369/0022155412441002  0.382
2012 Paulose T, Hannon PR, Peretz J, Craig ZR, Flaws JA. Estrogen receptor alpha overexpressing mouse antral follicles are sensitive to atresia induced by methoxychlor and its metabolites. Reproductive Toxicology (Elmsford, N.Y.). 33: 353-60. PMID 22306526 DOI: 10.1016/J.Reprotox.2012.01.007  0.802
2012 Wang W, Craig ZR, Basavarajappa MS, Gupta RK, Flaws JA. Di (2-ethylhexyl) phthalate inhibits growth of mouse ovarian antral follicles through an oxidative stress pathway. Toxicology and Applied Pharmacology. 258: 288-95. PMID 22155089 DOI: 10.1016/J.Taap.2011.11.008  0.759
2012 Ziv-Gal A, Gallicchio L, Miller SR, Zacur HA, Flaws JA. A genetic polymorphism in the CYP19A1 gene and the risk of hypertension among midlife women. Maturitas. 71: 70-5. PMID 22104650 DOI: 10.1016/J.Maturitas.2011.10.012  0.723
2012 Ziv-Gal A, Craig ZR, Wang W, Flaws JA. Bisphenol A and Expression of Cell Cycle Regulators and Apoptotic Factors in Cultured Mouse Ovarian Antral Follicles. Biology of Reproduction. 87: 262-262. DOI: 10.1093/Biolreprod/87.S1.262  0.76
2012 Hannon PR, Flaws JA. Di(2-ethylhexyl) Phthalate Alters Mouse Ovarian Follicle Numbers and Atresia In Vivo. Biology of Reproduction. 87: 260-260. DOI: 10.1093/Biolreprod/87.S1.260  0.363
2012 Craig ZR, Hannon PR, Wang W, Flaws JA. Dibutyl Phthalate (DBP) Induces Cell Cycle Arrest and Apoptosis in Ovarian Antral Follicles. Biology of Reproduction. 87: 250-250. DOI: 10.1093/Biolreprod/87.S1.250  0.315
2012 Peretz J, Craig Z, Flaws JA. Bisphenol A Targets Atresia Factors and Cell Cycle Regulators to Inhibit Ovarian Antral Follicle Growth. Biology of Reproduction. 87: 249-249. DOI: 10.1093/Biolreprod/87.S1.249  0.746
2011 Craig ZR, Wang W, Flaws JA. Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling. Reproduction (Cambridge, England). 142: 633-46. PMID 21862696 DOI: 10.1530/Rep-11-0136  0.387
2011 Basavarajappa MS, Craig ZR, Hernández-Ochoa I, Paulose T, Leslie TC, Flaws JA. Methoxychlor reduces estradiol levels by altering steroidogenesis and metabolism in mouse antral follicles in vitro. Toxicology and Applied Pharmacology. 253: 161-9. PMID 21514315 DOI: 10.1016/J.Taap.2011.04.007  0.796
2011 Gawriluk TR, Hale AN, Flaws JA, Dillon CP, Green DR, Rucker EB. Autophagy is a cell survival program for female germ cells in the murine ovary. Reproduction (Cambridge, England). 141: 759-65. PMID 21464117 DOI: 10.1530/Rep-10-0489  0.314
2011 Paulose T, Hernández-Ochoa I, Basavarajappa MS, Peretz J, Flaws JA. Increased sensitivity of estrogen receptor alpha overexpressing antral follicles to methoxychlor and its metabolites. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 447-59. PMID 21252393 DOI: 10.1093/Toxsci/Kfr011  0.81
2011 Peretz J, Gupta RK, Singh J, Hernández-Ochoa I, Flaws JA. Bisphenol A impairs follicle growth, inhibits steroidogenesis, and downregulates rate-limiting enzymes in the estradiol biosynthesis pathway. Toxicological Sciences : An Official Journal of the Society of Toxicology. 119: 209-17. PMID 20956811 DOI: 10.1093/Toxsci/Kfq319  0.784
2011 Heath J, Abdelmageed Y, Braden TD, Williams CS, Williams JW, Paulose T, Hernandez-Ochoa I, Gupta R, Flaws JA, Goyal HO. Genetically induced estrogen receptor α mRNA (Esr1) overexpression does not adversely affect fertility or penile development in male mice. Journal of Andrology. 32: 282-94. PMID 20930192 DOI: 10.2164/Jandrol.110.010769  0.795
2011 Wang W, Craig ZR, Basavarajappa M, Gupta R, Flaws JA. Di-(2-ethylhexyl) Phthalate Inhibits Growth of Ovarian Antral Follicles Through an Oxidative Stress Pathway. Biology of Reproduction. 85: 40-40. DOI: 10.1093/Biolreprod/85.S1.40  0.728
2011 Basavarajappa MS, Hernandez-Ochoa I, Karman BS, Craig ZR, Wang W, Flaws JA. Methoxychlor Alters Pro-Apoptotic and Anti-Apoptotic Factors in the Antral Follicles of the Mouse Ovary. Biology of Reproduction. 85: 286-286. DOI: 10.1093/Biolreprod/85.S1.286  0.725
2011 Karman BN, Basavarajappa MS, Craig ZR, Flaws JA. 2,3,7,8-Tetrachlorodibenzo-p-dioxin Activates the AHR Pathway and Alters Estradiol Levels Without Affecting Growth in CD-1 Mouse Antral Follicles In Vitro. Biology of Reproduction. 85: 284-284. DOI: 10.1093/Biolreprod/85.S1.284  0.783
2011 Hannon PR, Craig ZR, Flaws JA. Dibutyl Phthalate (DBP) Alters the Levels of Cell Proliferation and Apoptosis Genes in Mouse Granulosa Cells. Biology of Reproduction. 85: 276-276. DOI: 10.1093/Biolreprod/85.S1.276  0.302
2011 Craig ZR, Hannon PR, Flaws JA. Dibutyl Phthalate (DBP) Suppresses Growth of Isolated Mouse Antral Follicles. Biology of Reproduction. 85: 270-270. DOI: 10.1093/Biolreprod/85.S1.270  0.32
2011 Peretz J, Flaws JA. Bisphenol A May Target Cytochrome P45011a1 to Inhibit Steroidogenesis in Mouse Antral Follicles. Biology of Reproduction. 85: 265-265. DOI: 10.1093/Biolreprod/85.S1.265  0.718
2010 Ziv-Gal A, Flaws JA. Factors that may influence the experience of hot flushes by healthy middle-aged women. Journal of Women's Health (2002). 19: 1905-14. PMID 20831431 DOI: 10.1089/Jwh.2009.1852  0.721
2010 Hernandez-Ochoa I, Barnett-Ringgold KR, Dehlinger SL, Gupta RK, Leslie TC, Roby KF, Flaws JA. The ability of the aryl hydrocarbon receptor to regulate ovarian follicle growth and estradiol biosynthesis in mice depends on stage of sexual maturity. Biology of Reproduction. 83: 698-706. PMID 20631400 DOI: 10.1095/Biolreprod.110.087015  0.457
2010 Cimafranca MA, Davila J, Ekman GC, Andrews RN, Neese SL, Peretz J, Woodling KA, Helferich WG, Sarkar J, Flaws JA, Schantz SL, Doerge DR, Cooke PS. Acute and chronic effects of oral genistein administration in neonatal mice. Biology of Reproduction. 83: 114-21. PMID 20357267 DOI: 10.1095/Biolreprod.109.080549  0.743
2010 Gupta RK, Singh JM, Leslie TC, Meachum S, Flaws JA, Yao HH. Di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate inhibit growth and reduce estradiol levels of antral follicles in vitro. Toxicology and Applied Pharmacology. 242: 224-30. PMID 19874833 DOI: 10.1016/J.Taap.2009.10.011  0.443
2010 Gallicchio L, Miller S, Greene T, Zacur H, Flaws JA. Menstrual cycle abnormalities among cosmetologists: the Reproductive Outcomes in Salon Employees (ROSE) study. Reproductive Sciences (Thousand Oaks, Calif.). 17: 20-8. PMID 19767543 DOI: 10.1177/1933719109345163  0.315
2010 Alexander C, Cochran CJ, Gallicchio L, Miller SR, Flaws JA, Zacur H. Serum leptin levels, hormone levels, and hot flashes in midlife women. Fertility and Sterility. 94: 1037-43. PMID 19476935 DOI: 10.1016/J.Fertnstert.2009.04.001  0.323
2010 Gupta RK, Archambeault DR, Singh JM, Flaws JA, Yao HH. Exposure to Low Dose Bisphenol-A Affects Ovarian Development in the Mouse. Biology of Reproduction. 83: 74-74. DOI: 10.1093/Biolreprod/83.S1.74  0.33
2010 Dehlinger SL, Hernandez-Ochoa I, Basavarajappa MS, Peretz J, Flaws JA. Follicle-Stimulating Hormone Restores Growth in Follicles Lacking the Aryl Hydrocarbon Receptor. Biology of Reproduction. 83: 619-619. DOI: 10.1093/Biolreprod/83.S1.619  0.799
2010 Archambeault DR, Gupta RK, Huang JC, Flaws JA, Yao HH. In Utero Exposure to Bisphenol A Recapitulates the Fetal Testis Cord Dysgenesis Phenotype of Activin A Knockout Mice. Biology of Reproduction. 83: 290-290. DOI: 10.1093/Biolreprod/83.S1.290  0.317
2010 Craig ZR, Karman BN, Gupta RK, Paulose T, Flaws JA. 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane (mono-OH methoxychlor) Alters mRNA Expression of Key Steroidogenic Enzymes in Cultured Mouse Antral Follicles. Biology of Reproduction. 83: 284-284. DOI: 10.1093/Biolreprod/83.S1.284  0.771
2010 Peretz J, Hernandez-Ochoa I, Flaws JA. Bisphenol A Alters Steroidogenic Acute Regulatory Protein and Progesterone Receptor Gene Expression in the Mouse Ovarian Antral Follicle. Biology of Reproduction. 83: 283-283. DOI: 10.1093/Biolreprod/83.S1.283  0.748
2010 Paulose T, Hernandez-Ochoa I, Flaws JA. Alterations in Gene Expression Levels in Estrogen Receptor Alpha Overexpressing Antral Follicles Treated with Methoxychlor. Biology of Reproduction. 83: 282-282. DOI: 10.1093/Biolreprod/83.S1.282  0.781
2010 Basavarajappa MS, Hernandez-Ochoa I, Singh J, Flaws JA. Methoxychlor Induces Atresia and Decreases Estradiol Levels in Antral Follicles Simultaneously. Biology of Reproduction. 83: 281-281. DOI: 10.1093/Biolreprod/83.S1.281  0.749
2010 Singh JM, Gupta RK, Flaws JA. Mono-(2-ethylhexyl) Phthalate Inhibits Expression of Antioxidant Enzymes in Mouse Antral Follicles. Biology of Reproduction. 83: 280-280. DOI: 10.1093/Biolreprod/83.S1.280  0.3
2010 Heath J, Abdelmageed Y, Braden T, Williams C, Williams JW, Paulose T, Ochoa IH, Gupta R, Flaws JA, Goyal HO. Genetically-Induced Estrogen Receptor Alpha (ESR1) Overexpression Does Not Adversely Affect Fertility or Penile Development in Male Mice. Biology of Reproduction. 83: 273-273. DOI: 10.1093/Biolreprod/83.S1.273  0.786
2010 Flaws JA, Basavarajappa M, Gupta R. The Effects of Methoxychlor on the Mammalian Ovary. Biology of Reproduction. 83: 210-210. DOI: 10.1093/Biolreprod/83.S1.210  0.724
2009 Gupta RK, Meachum S, Hernández-Ochoa I, Peretz J, Yao HH, Flaws JA. Methoxychlor inhibits growth of antral follicles by altering cell cycle regulators. Toxicology and Applied Pharmacology. 240: 1-7. PMID 19615393 DOI: 10.1016/J.Taap.2009.07.007  0.755
2009 Peretz J, Gallicchio L, Miller S, Greene T, Zacur H, Flaws JA. Infertility among cosmetologists. Reproductive Toxicology (Elmsford, N.Y.). 28: 359-64. PMID 19481600 DOI: 10.1016/J.Reprotox.2009.05.068  0.707
2009 Hernández-Ochoa I, Karman BN, Flaws JA. The role of the aryl hydrocarbon receptor in the female reproductive system. Biochemical Pharmacology. 77: 547-59. PMID 18977336 DOI: 10.1016/J.Bcp.2008.09.037  0.803
2009 Peretz J, Paulose T, Hernandez Ochoa MI, Flaws JA. Exposure to Bisphenol A Inhibits Ovarian Follicle Growth and Hormone Production in the Mouse. Biology of Reproduction. 81: 639-639. DOI: 10.1093/Biolreprod/81.S1.639  0.805
2009 Gupta RK, Singh J, Meachum S, Flaws JA, Yao HHC. Phthalate Esters Affect Expression of Aromatase and Cell Cycle Regulators in Mouse Ovarian Antral Follicles. Biology of Reproduction. 81: 632-632. DOI: 10.1093/Biolreprod/81.S1.632  0.369
2009 Hernandez-Ochoa I, Leslie T, Dehlinger SL, Gupta RK, Flaws JA. The Aryl Hydrocarbon Receptor May Restore Ovarian Follicle Growth by Regulating Estradiol Biosynthesis in Cycling Adult Mice. Biology of Reproduction. 81: 307-307. DOI: 10.1093/Biolreprod/81.S1.307  0.413
2009 Karman BN, Flaws JA. The Aryl Hydrocarbon Receptor May Regulate Genes Involved in Cell Cycle and X Chromosome Inactivation in the Neonatal Mouse Ovary. Biology of Reproduction. 81: 201-201. DOI: 10.1093/Biolreprod/81.S1.201  0.78
2008 Weck RL, Paulose T, Flaws JA. Impact of environmental factors and poverty on pregnancy outcomes. Clinical Obstetrics and Gynecology. 51: 349-59. PMID 18463465 DOI: 10.1097/Grf.0B013E31816F276E  0.751
2008 Karman BN, Flaws JA. The Aryl Hydrocarbon Receptor May Regulate the Number of Germ Cell Nests During Neonatal Life in the Mouse. Biology of Reproduction. 78: 222-223. DOI: 10.1093/Biolreprod/78.S1.222C  0.783
2008 Leslie T, Gupta RK, Flaws J. Methoxychlor Decreases Sex Steroid Production by Mouse Antral Follicles. Biology of Reproduction. 78: 202-202. DOI: 10.1093/Biolreprod/78.S1.202  0.332
2008 Hernandez Ochoa MI, Ringgold KR, Leslie T, Gupta RK, Flaws JA. The Ability of the Aryl Hydrocarbon Receptor to Regulate Steroidogenesis May Depend on Sexual Maturity in Mice. Biology of Reproduction. 78: 178-178. DOI: 10.1093/Biolreprod/78.S1.178  0.311
2008 Gupta RK, Leslie T, Krawzak R, Flaws JA, Yao HH. Phthalate Esters Inhibit Growth and Reduce Estradiol Levels in Mouse Ovarian Antral Follicles. Biology of Reproduction. 78: 153-154. DOI: 10.1093/Biolreprod/78.S1.153D  0.402
2008 Krawzak RM, Gupta RK, Basavarajappa MS, Flaws JA. Methoxychlor Alters the Steroidogenesis Pathway in the Mouse Ovary. Biology of Reproduction. 78: 153-153. DOI: 10.1093/Biolreprod/78.S1.153C  0.728
2008 Basavarajappa MS, Gupta RK, Weck R, Flaws JA. Methoxychlor Reduces Aryl Hydrocarbon Receptor Levels in the Mouse Ovary. Biology of Reproduction. 78: 153-153. DOI: 10.1093/Biolreprod/78.S1.153B  0.743
2008 Paulose T, Peretz J, Flaws JA. Estrogen Receptor alpha Overexpression Alters Expression of Other Receptors in the Mouse Ovary. Biology of Reproduction. 78: 151-151. DOI: 10.1093/Biolreprod/78.S1.151  0.783
2007 Gupta RK, Aberdeen G, Babus JK, Albrecht ED, Flaws JA. Methoxychlor and its metabolites inhibit growth and induce atresia of baboon antral follicles. Toxicologic Pathology. 35: 649-56. PMID 17676523 DOI: 10.1080/01926230701459960  0.38
2007 Greenfeld CR, Pepling ME, Babus JK, Furth PA, Flaws JA. BAX regulates follicular endowment in mice. Reproduction (Cambridge, England). 133: 865-76. PMID 17616717 DOI: 10.1530/Rep-06-0270  0.406
2007 Barnett KR, Tomic D, Gupta RK, Babus JK, Roby KF, Terranova PF, Flaws JA. The aryl hydrocarbon receptor is required for normal gonadotropin responsiveness in the mouse ovary. Toxicology and Applied Pharmacology. 223: 66-72. PMID 17594909 DOI: 10.1016/J.Taap.2007.05.014  0.43
2007 Schilling C, Gallicchio L, Miller SR, Langenberg P, Zacur H, Flaws JA. Relation of body mass and sex steroid hormone levels to hot flushes in a sample of mid-life women. Climacteric. 10: 27-37. PMID 17364602 DOI: 10.1080/13697130601164755  0.318
2007 Barnett KR, Tomic D, Gupta RK, Miller KP, Meachum S, Paulose T, Flaws JA. The aryl hydrocarbon receptor affects mouse ovarian follicle growth via mechanisms involving estradiol regulation and responsiveness. Biology of Reproduction. 76: 1062-70. PMID 17329597 DOI: 10.1095/Biolreprod.106.057687  0.81
2007 Greenfeld CR, Babus JK, Furth PA, Marion S, Hoyer PB, Flaws JA. BAX is involved in regulating follicular growth, but is dispensable for follicle atresia in adult mouse ovaries. Reproduction (Cambridge, England). 133: 107-16. PMID 17244737 DOI: 10.1530/Rep-06-0144  0.409
2007 Schilling C, Gallicchio L, Miller SR, Langenberg P, Zacur H, Flaws JA. Genetic polymorphisms, hormone levels, and hot flashes in midlife women. Maturitas. 57: 120-31. PMID 17187946 DOI: 10.1016/J.Maturitas.2006.11.009  0.33
2007 Greenfeld CR, Roby KF, Pepling ME, Babus JK, Terranova PF, Flaws JA. Tumor necrosis factor (TNF) receptor type 2 is an important mediator of TNF alpha function in the mouse ovary. Biology of Reproduction. 76: 224-31. PMID 17065602 DOI: 10.1095/Biolreprod.106.055509  0.388
2007 Tomic D, Frech MS, Babus JK, Symonds D, Furth PA, Koos RD, Flaws JA. Effects of ERalpha overexpression on female reproduction in mice. Reproductive Toxicology (Elmsford, N.Y.). 23: 317-25. PMID 17011746 DOI: 10.1016/J.Reprotox.2006.08.004  0.383
2007 Paulose T, Flaws J. CONDITIONAL OVEREXPRESSION OF ESTROGEN RECEPTOR ALPHA IN THE MOUSE OVARY Biology of Reproduction. 77: 77-77. DOI: 10.1093/Biolreprod/77.S1.77B  0.768
2007 Gupta R, Meachum S, Yao H, Flaws J. METHOXYCHLOR EXPOSURE REDUCES THE LEVELS OF CELL CYCLE REGULATORS IN MOUSE OVARIAN ANTRAL FOLLICLES Biology of Reproduction. 77: 151-152. DOI: 10.1093/Biolreprod/77.S1.151B  0.395
2006 Gupta RK, Schuh RA, Fiskum G, Flaws JA. Methoxychlor causes mitochondrial dysfunction and oxidative damage in the mouse ovary. Toxicology and Applied Pharmacology. 216: 436-45. PMID 16890261 DOI: 10.1016/J.Taap.2006.06.013  0.329
2006 Gupta RK, Miller KP, Babus JK, Flaws JA. Methoxychlor inhibits growth and induces atresia of antral follicles through an oxidative stress pathway. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 382-9. PMID 16807286 DOI: 10.1093/Toxsci/Kfl052  0.398
2006 Tomic D, Frech MS, Babus JK, Gupta RK, Furth PA, Koos RD, Flaws JA. Methoxychlor induces atresia of antral follicles in ERalpha-overexpressing mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 196-204. PMID 16787999 DOI: 10.1093/Toxsci/Kfl040  0.386
2006 Miller KP, Gupta RK, Flaws JA. Methoxychlor metabolites may cause ovarian toxicity through estrogen-regulated pathways. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 180-8. PMID 16760418 DOI: 10.1093/Toxsci/Kfl034  0.427
2006 Barnett KR, Schilling C, Greenfeld CR, Tomic D, Flaws JA. Ovarian follicle development and transgenic mouse models Human Reproduction Update. 12: 537-555. PMID 16728463 DOI: 10.1093/Humupd/Dml022  0.385
2006 Flaws JA, Marion SL, Miller KP, Christian PJ, Babus JK, Hoyer PB. Effect of bcl-2 overexpression in mice on ovotoxicity caused by 4-vinylcyclohexene. Toxicology and Applied Pharmacology. 215: 51-6. PMID 16631218 DOI: 10.1016/J.Taap.2006.03.003  0.378
2006 Symonds DA, Miller KP, Tomic D, Flaws JA. Effect of methoxychlor and estradiol on cytochrome p450 enzymes in the mouse ovarian surface epithelium. Toxicological Sciences : An Official Journal of the Society of Toxicology. 89: 510-4. PMID 16280380 DOI: 10.1093/Toxsci/Kfj044  0.35
2005 Visvanathan K, Gallicchio L, Schilling C, Babus JK, Lewis LM, Miller SR, Zacur H, Flaws JA. Cytochrome gene polymorphisms, serum estrogens, and hot flushes in midlife women. Obstetrics and Gynecology. 106: 1372-81. PMID 16319265 DOI: 10.1097/01.Aog.0000187308.67021.98  0.317
2005 Schuh RA, Kristián T, Gupta RK, Flaws JA, Fiskum G. Methoxychlor inhibits brain mitochondrial respiration and increases hydrogen peroxide production and CREB phosphorylation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 495-504. PMID 16177237 DOI: 10.1093/Toxsci/Kfi334  0.318
2005 Miller KP, Gupta RK, Greenfeld CR, Babus JK, Flaws JA. Methoxychlor directly affects ovarian antral follicle growth and atresia through Bcl-2- and Bax-mediated pathways. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 213-21. PMID 16081520 DOI: 10.1093/Toxsci/Kfi276  0.401
2005 Gupta RK, Flaws JA. Gonadotropin-releasing hormone (GnRH) analogues and the ovary: do GnRH antagonists destroy primordial follicles? Fertility and Sterility. 83: 1339-42. PMID 15866566 DOI: 10.1016/J.Fertnstert.2005.01.089  0.322
2005 Thompson KE, Bourguet SM, Christian PJ, Benedict JC, Sipes IG, Flaws JA, Hoyer PB. Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss. Toxicology and Applied Pharmacology. 203: 114-23. PMID 15710172 DOI: 10.1016/J.Taap.2004.07.010  0.36
2005 Symonds DA, Tomic D, Miller KP, Flaws JA. Methoxychlor induces proliferation of the mouse ovarian surface epithelium. Toxicological Sciences : An Official Journal of the Society of Toxicology. 83: 355-62. PMID 15525693 DOI: 10.1093/Toxsci/Kfi024  0.353
2004 Miller KP, Borgeest C, Greenfeld C, Tomic D, Flaws JA. In utero effects of chemicals on reproductive tissues in females. Toxicology and Applied Pharmacology. 198: 111-31. PMID 15236949 DOI: 10.1016/J.Taap.2003.07.016  0.348
2004 Tomic D, Miller KP, Kenny HA, Woodruff TK, Hoyer P, Flaws JA. Ovarian follicle development requires Smad3. Molecular Endocrinology (Baltimore, Md.). 18: 2224-40. PMID 15192076 DOI: 10.1210/Me.2003-0414  0.419
2004 Borgeest C, Miller KP, Gupta R, Greenfeld C, Hruska KS, Hoyer P, Flaws JA. Methoxychlor-induced atresia in the mouse involves Bcl-2 family members, but not gonadotropins or estradiol. Biology of Reproduction. 70: 1828-35. PMID 14973267 DOI: 10.1095/Biolreprod.103.022889  0.446
2004 Sharan SK, Pyle A, Coppola V, Babus J, Swaminathan S, Benedict J, Swing D, Martin BK, Tessarollo L, Evans JP, Flaws JA, Handel MA. BRCA2 deficiency in mice leads to meiotic impairment and infertility. Development (Cambridge, England). 131: 131-42. PMID 14660434 DOI: 10.1242/Dev.00888  0.343
2003 Tilli MT, Frech MS, Steed ME, Hruska KS, Johnson MD, Flaws JA, Furth PA. Introduction of estrogen receptor-alpha into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma. The American Journal of Pathology. 163: 1713-9. PMID 14578170 DOI: 10.1016/S0002-9440(10)63529-8  0.351
2003 Symonds D, Tomic D, Borgeest C, McGee E, Flaws JA. Smad 3 regulates proliferation of the mouse ovarian surface epithelium. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 273: 681-6. PMID 12845704 DOI: 10.1002/Ar.A.10090  0.389
2003 Romani W, Patrie J, Curl LA, Flaws JA. The correlations between estradiol, estrone, estriol, progesterone, and sex hormone-binding globulin and anterior cruciate ligament stiffness in healthy, active females. Journal of Womens Health. 12: 287-298. PMID 12804359 DOI: 10.1089/154099903321667627  0.312
2003 Li M, Ren S, Tilli MT, Flaws JA, Lubet R, Grubbs CJ, Furth PA. Chemoprevention of mammary carcinogenesis in a transgenic mouse model by alpha-difluoromethylornithine (DFMO) in the diet is associated with decreased cyclin D1 activity. Oncogene. 22: 2568-72. PMID 12730671 DOI: 10.1038/Sj.Onc.1206314  0.315
2003 Benedict JC, Miller KP, Lin TM, Greenfeld C, Babus JK, Peterson RE, Flaws JA. Aryl hydrocarbon receptor regulates growth, but not atresia, of mouse preantral and antral follicles. Biology of Reproduction. 68: 1511-7. PMID 12606443 DOI: 10.1095/Biolreprod.102.007492  0.445
2002 Silbergeld EK, Flaws JA. Environmental exposures and women's health. Clinical Obstetrics and Gynecology. 45: 1119-28. PMID 12438889 DOI: 10.1097/00003081-200212000-00019  0.312
2002 Hruska KS, Tilli MT, Ren S, Cotarla I, Kwong T, Li M, Fondell JD, Hewitt JA, Koos RD, Furth PA, Flaws JA. Conditional over-expression of estrogen receptor alpha in a transgenic mouse model. Transgenic Research. 11: 361-72. PMID 12212839 DOI: 10.1023/A:1016376100186  0.369
2002 Hu X, Flaws JA, Sipes IG, Hoyer PB. Activation of mitogen-activated protein kinases and AP-1 transcription factor in ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats. Biology of Reproduction. 67: 718-24. PMID 12193377 DOI: 10.1095/Biolreprod.102.004259  0.305
2002 Borgeest C, Greenfeld C, Tomic D, Flaws JA. The effects of endocrine disrupting chemicals on the ovary. Frontiers in Bioscience. 7. PMID 12161337 DOI: 10.2741/Borgees  0.365
2002 Borgeest C, Symonds D, Mayer LP, Hoyer PB, Flaws JA. Methoxychlor may cause ovarian follicular atresia and proliferation of the ovarian epithelium in the mouse. Toxicological Sciences : An Official Journal of the Society of Toxicology. 68: 473-8. PMID 12151644 DOI: 10.1093/Toxsci/68.2.473  0.342
2002 Silbergeld EK, Flaws JA, Brown KM. Organizational and activational effects of estrogenic endocrine disrupting chemicals. Cadernos De SaúDe PúBlica. 18: 495-504. PMID 11923891 DOI: 10.1590/S0102-311X2002000200014  0.317
2002 Tomic D, Brodie SG, Deng C, Hickey RJ, Babus JK, Malkas LH, Flaws JA. Smad 3 May Regulate Follicular Growth in the Mouse Ovary Biology of Reproduction. 66: 917-923. PMID 11906909 DOI: 10.1095/Biolreprod66.4.917  0.414
2002 Le Provost F, Riedlinger G, Yim SH, Benedict J, Gonzalez FJ, Flaws J, Hennighausen L. The aryl hydrocarbon receptor (AhR) and its nuclear translocator (Arnt) are dispensable for normal mammary gland development but are required for fertility Genesis. 32: 231-239. PMID 11892012 DOI: 10.1002/Gene.10037  0.377
2002 Cui Y, Miyoshi K, Claudio E, Siebenlist UK, Gonzalez FJ, Flaws J, Wagner KU, Hennighausen L. Loss of the peroxisome proliferation-activated receptor gamma (PPARgamma ) does not affect mammary development and propensity for tumor formation but leads to reduced fertility. The Journal of Biological Chemistry. 277: 17830-5. PMID 11884400 DOI: 10.1074/Jbc.M200186200  0.37
2001 Lewis BC, Hudgins S, Lewis A, Schorr K, Sommer R, Peterson RE, Flaws JA, Furth PA. In utero and lactational treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs mammary gland differentiation but does not block the response to exogenous estrogen in the postpubertal female rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. 62: 46-53. PMID 11399792 DOI: 10.1093/Toxsci/62.1.46  0.404
2001 Flaws JA, Langenberg P, Babus JK, Hirshfield AN, Sharara FI. Ovarian volume and antral follicle counts as indicators of menopausal status. Menopause (New York, N.Y.). 8: 175-80. PMID 11355039 DOI: 10.1097/00042192-200105000-00006  0.345
2001 Flaws JA, Hirshfield AN, Hewitt JA, Babus JK, Furth PA. Effect of bcl-2 on the primordial follicle endowment in the mouse ovary. Biology of Reproduction. 64: 1153-9. PMID 11259262 DOI: 10.1095/Biolreprod64.4.1153  0.372
2001 Hruska KS, Furth PA, Seifer DB, Sharara FI, Flaws JA. Environmental factors in infertility. Clinical Obstetrics and Gynecology. 43: 821-9. PMID 11100299 DOI: 10.1097/00003081-200012000-00014  0.307
2000 Benedict JC, Lin TM, Loeffler IK, Peterson RE, Flaws JA. Physiological role of the aryl hydrocarbon receptor in mouse ovary development. Toxicological Sciences : An Official Journal of the Society of Toxicology. 56: 382-8. PMID 10910997 DOI: 10.1093/Toxsci/56.2.382  0.37
2000 Rucker EB, Dierisseau P, Wagner KU, Garrett L, Wynshaw-Boris A, Flaws JA, Hennighausen L. Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis Molecular Endocrinology. 14: 1038-1052. PMID 10894153 DOI: 10.1210/Mend.14.7.0465  0.306
2000 Flaws JA, Sharara FI, Silbergeld EK, Hirshfield AN. 50 – Environmental Exposures and Women's Reproductive Health Women & Health. 625-633. DOI: 10.1016/B978-012288145-9/50058-9  0.351
1999 Whiteman MK, Cui Y, Flaws JA, Espeland M, Bush TL. Low fibrinogen level: A predisposing factor for venous thromboembolic events with hormone replacement therapy. American Journal of Hematology. 61: 271-273. PMID 10440916 DOI: 10.1002/(Sici)1096-8652(199908)61:4<271::Aid-Ajh10>3.0.Co;2-0  0.304
1999 Silbergeld EK, Flaws JA. Chemicals and menopause: Effects on age at menopause and on health status in the postmenopausal period Journal of Women's Health. 8: 227-234. PMID 10100136 DOI: 10.1089/Jwh.1999.8.227  0.315
1999 Perez GI, Robles R, Knudson CM, Flaws JA, Korsmeyer SJ, Tilly JL. Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency. Nature Genetics. 21: 200-3. PMID 9988273 DOI: 10.1038/5985  0.378
1998 Sharara FI, Seifer DB, Flaws JA. Environmental toxicants and female reproduction 4 Fertility and Sterility. 70: 613-622. PMID 9797086 DOI: 10.1016/S0015-0282(98)00253-2  0.37
1998 Biegel LB, Flaws JA, Hirshfield AN, O'Connor JC, Elliott GS, Ladics GS, Silbergeld EK, Van Pelt CS, Hurtt ME, Cook JC, Frame SR. 90-day feeding and one-generation reproduction study in Crl:CD BR rats with 17 beta-estradiol. Toxicological Sciences : An Official Journal of the Society of Toxicology. 44: 116-42. PMID 9742652 DOI: 10.1006/Toxs.1998.2468  0.313
1997 Flaws JA, Sommer RJ, Silbergeld EK, Peterson RE, Hirshfield AN. In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces genital dysmorphogenesis in the female rat. Toxicology and Applied Pharmacology. 147: 351-62. PMID 9439730 DOI: 10.1006/Taap.1997.8295  0.381
1997 Flaws JA, Abbud R, Mann RJ, Nilson JH, Hirshfield AN. Chronically elevated luteinizing hormone depletes primordial follicles in the mouse ovary. Biology of Reproduction. 57: 1233-7. PMID 9369192 DOI: 10.1095/Biolreprod57.5.1233  0.399
1996 Springer LN, Flaws JA, Sipes IG, Hoyer PB. Follicular mechanisms associated with 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats. Reproductive Toxicology (Elmsford, N.Y.). 10: 137-43. PMID 8919611 DOI: 10.1016/0890-6238(95)02056-X  0.327
1996 Springer LN, McAsey ME, Flaws JA, Tilly JL, Sipes IG, Hoyer PB. Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats. Toxicology and Applied Pharmacology. 139: 394-401. PMID 8806857 DOI: 10.1006/Taap.1996.0180  0.321
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