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Michael H. Hecht - Publications

Affiliations: 
Chemistry Princeton University, Princeton, NJ 
Area:
Synthetic Biology and Alzheimer's Disease
Website:
http://www.princeton.edu/chemistry/faculty/profiles/hecht/

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang MS, Hoegler KJ, Hecht MH. Unevolved De Novo Proteins Have Innate Tendencies to Bind Transition Metals. Life (Basel, Switzerland). 9. PMID 30634485 DOI: 10.3390/life9010008  1
2018 Hoegler KJ, Hecht MH. Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity. Journal of Molecular Evolution. PMID 29356848 DOI: 10.1007/s00239-018-9830-3  1
2018 Donnelly AE, Murphy GS, Digianantonio KM, Hecht MH. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nature Chemical Biology. PMID 29334382 DOI: 10.1038/nchembio.2550  0.32
2017 Digianantonio KM, Korolev M, Hecht MH. A Non-Natural Protein Rescues Cells Deleted for a Key Enzyme in Central Metabolism. Acs Synthetic Biology. PMID 28055179 DOI: 10.1021/acssynbio.6b00336  0.32
2016 Digianantonio KM, Hecht MH. A protein constructed de novo enables cell growth by altering gene regulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884172 DOI: 10.1073/pnas.1600566113  1
2016 Hoegler KJ, Hecht MH. A De Novo Protein Confers Copper Resistance in Escherichia Coli. Protein Science : a Publication of the Protein Society. PMID 26748884 DOI: 10.1002/pro.2871  1
2015 Murphy GS, Greisman JB, Hecht MH. De Novo Proteins with Life-Sustaining Functions are Structurally Dynamic. Journal of Molecular Biology. PMID 26707197 DOI: 10.1016/j.jmb.2015.12.008  1
2015 Kobayashi N, Yasase K, Sato T, Unzai S, Hecht MH, Arai R. Self-Assembling Nano-Architectures Created from a Protein Nano-Building Block Using an Intermolecularly Folded Dimeric De Novo Protein. Journal of the American Chemical Society. PMID 26120734 DOI: 10.1021/jacs.5b03593  1
2015 Smith BA, Mularz AE, Hecht MH. Divergent evolution of a bifunctional de novo protein. Protein Science : a Publication of the Protein Society. 24: 246-52. PMID 25420677 DOI: 10.1002/pro.2611  1
2014 McKoy AF, Chen J, Schupbach T, Hecht MH. Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42. Chemical Biology & Drug Design. 84: 505-12. PMID 24751138 DOI: 10.1111/cbdd.12341  1
2013 McKay CP, Stoker CR, Glass BJ, Davé AI, Davila AF, Heldmann JL, Marinova MM, Fairen AG, Quinn RC, Zacny KA, Paulsen G, Smith PH, Parro V, Andersen DT, Hecht MH, et al. The Icebreaker Life Mission to Mars: a search for biomolecular evidence for life. Astrobiology. 13: 334-53. PMID 23560417 DOI: 10.1089/ast.2012.0878  0.32
2012 Cherny I, Korolev M, Koehler AN, Hecht MH. Proteins from an unevolved library of de novo designed sequences bind a range of small molecules. Acs Synthetic Biology. 1: 130-8. PMID 23651114 DOI: 10.1021/sb200018e  1
2012 McKoy AF, Chen J, Schupbach T, Hecht MH. A novel inhibitor of amyloid β (Aβ) peptide aggregation: from high throughput screening to efficacy in an animal model of Alzheimer disease. The Journal of Biological Chemistry. 287: 38992-9000. PMID 22992731 DOI: 10.1074/jbc.M112.348037  1
2012 Patel SC, Hecht MH. Directed evolution of the peroxidase activity of a de novo-designed protein. Protein Engineering, Design & Selection : Peds. 25: 445-52. PMID 22665824 DOI: 10.1093/protein/gzs025  1
2012 Arai R, Kobayashi N, Kimura A, Sato T, Matsuo K, Wang AF, Platt JM, Bradley LH, Hecht MH. Domain-swapped dimeric structure of a stable and functional de novo four-helix bundle protein, WA20. The Journal of Physical Chemistry. B. 116: 6789-97. PMID 22397676 DOI: 10.1021/jp212438h  1
2012 Goetz W, Hecht MH, Hviid SF, Madsen MB, Pike WT, Staufer U, Velbel MA, Harrit NH, Zych E, Edgett KS. Search for ultraviolet luminescence of soil particles at the Phoenix landing site, Mars Planetary and Space Science. 70: 134-147. DOI: 10.1016/j.pss.2012.05.002  0.32
2011 Sinha MP, Neidholdt EL, Hurowitz J, Sturhahn W, Beard B, Hecht MH. Laser ablation-miniature mass spectrometer for elemental and isotopic analysis of rocks. The Review of Scientific Instruments. 82: 094102. PMID 21974601 DOI: 10.1063/1.3626794  0.32
2011 Armstrong AH, Chen J, McKoy AF, Hecht MH. Mutations that replace aromatic side chains promote aggregation of the Alzheimer's Aβ peptide. Biochemistry. 50: 4058-67. PMID 21513285 DOI: 10.1021/bi200268w  1
2011 Smith BA, Hecht MH. Novel proteins: from fold to function. Current Opinion in Chemical Biology. 15: 421-6. PMID 21474363 DOI: 10.1016/j.cbpa.2011.03.006  1
2011 Das A, Wei Y, Pelczer I, Hecht MH. Binding of small molecules to cavity forming mutants of a de novo designed protein. Protein Science : a Publication of the Protein Society. 20: 702-11. PMID 21328630 DOI: 10.1002/pro.601  1
2011 Fisher MA, McKinley KL, Bradley LH, Viola SR, Hecht MH. De novo designed proteins from a library of artificial sequences function in Escherichia coli and enable cell growth. Plos One. 6: e15364. PMID 21245923 DOI: 10.1371/journal.pone.0015364  1
2011 Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, Vendruscolo M, Hayer-Hartl M, Hartl FU, Vabulas RM. Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions. Cell. 144: 67-78. PMID 21215370 DOI: 10.1016/j.cell.2010.11.050  1
2011 Pike WT, Staufer U, Hecht MH, Goetz W, Parrat D, Sykulska-Lawrence H, Vijendran S, Madsen MB. Quantification of the dry history of the Martian soil inferred from in situ microscopy Geophysical Research Letters. 38. DOI: 10.1029/2011GL049896  0.32
2011 Quinn RC, Chittenden JD, Kounaves SP, Hecht MH. The oxidation-reduction potential of aqueous soil solutions at the Mars Phoenix landing site Geophysical Research Letters. 38. DOI: 10.1029/2011GL047671  0.32
2010 Chen J, Armstrong AH, Koehler AN, Hecht MH. Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity. Journal of the American Chemical Society. 132: 17015-22. PMID 21062056 DOI: 10.1021/ja107552s  1
2010 Kounaves SP, Hecht MH, Kapit J, Quinn RC, Catling DC, Clark BC, Ming DW, Gospodinova K, Hredzak P, McElhoney K, Shusterman J. Soluble sulfate in the martian soil at the Phoenix landing site Geophysical Research Letters. 37. DOI: 10.1029/2010GL042613  0.32
2010 Goetz W, Pike WT, Hviid SF, Madsen MB, Morris RV, Hecht MH, Staufer U, Leer K, Sykulska H, Hemmig E, Marshall J, Morookian JM, Parrat D, Vijendran S, Bos BJ, et al. Microscopy analysis of soils at the Phoenix landing site, Mars: Classification of soil particles and description of their optical and magnetic properties Journal of Geophysical Research E: Planets. 115. DOI: 10.1029/2009JE003437  0.32
2010 Catling DC, Claire MW, Zahnle KJ, Quinn RC, Clark BC, Hecht MH, Kounaves S. Atmospheric origins of perchlorate on mars and in the atacama Journal of Geophysical Research E: Planets. 115. DOI: 10.1029/2009JE003425  0.32
2010 Kounaves SP, Hecht MH, Kapit J, Gospodinova K, Deflores L, Quinn RC, Boynton WV, Clark BC, Catling DC, Hredzak P, Ming DW, Moore Q, Shusterman J, Stroble S, West SJ, et al. Wet Chemistry experiments on the 2007 Phoenix Mars Scout Lander mission: Data analysis and results Journal of Geophysical Research E: Planets. 115. DOI: 10.1029/2009JE003424  0.32
2010 Fisher DA, Hecht MH, Kounaves S, Catling DC. A perchlorate brine lubricated deformable bed facilitating flow of the north polar cap of Mars: Possible mechanism for water table recharging Journal of Geophysical Research E: Planets. 115. DOI: 10.1029/2009JE003405  0.32
2009 Whiteway JA, Komguem L, Dickinson C, Cook C, Illnicki M, Seabrook J, Popovici V, Duck TJ, Davy R, Taylor PA, Pathak J, Fisher D, Carswell AI, Daly M, Hipkin V, ... ... Hecht MH, et al. Mars water-ice clouds and precipitation. Science (New York, N.Y.). 325: 68-70. PMID 19574386 DOI: 10.1126/science.1172344  0.32
2009 Hecht MH, Kounaves SP, Quinn RC, West SJ, Young SM, Ming DW, Catling DC, Clark BC, Boynton WV, Hoffman J, Deflores LP, Gospodinova K, Kapit J, Smith PH. Detection of perchlorate and the soluble chemistry of martian soil at the Phoenix lander site. Science (New York, N.Y.). 325: 64-7. PMID 19574385 DOI: 10.1126/science.1172466  0.32
2009 Boynton WV, Ming DW, Kounaves SP, Young SM, Arvidson RE, Hecht MH, Hoffman J, Niles PB, Hamara DK, Quinn RC, Smith PH, Sutter B, Catling DC, Morris RV. Evidence for calcium carbonate at the Mars Phoenix landing site. Science (New York, N.Y.). 325: 61-4. PMID 19574384 DOI: 10.1126/science.1172768  0.32
2009 Smith PH, Tamppari LK, Arvidson RE, Bass D, Blaney D, Boynton WV, Carswell A, Catling DC, Clark BC, Duck T, Dejong E, Fisher D, Goetz W, Gunnlaugsson HP, Hecht MH, et al. H2O at the Phoenix landing site. Science (New York, N.Y.). 325: 58-61. PMID 19574383 DOI: 10.1126/science.1172339  0.32
2009 Patel SC, Bradley LH, Jinadasa SP, Hecht MH. Cofactor binding and enzymatic activity in an unevolved superfamily of de novo designed 4-helix bundle proteins. Protein Science : a Publication of the Protein Society. 18: 1388-400. PMID 19544578 DOI: 10.1002/pro.147  1
2009 Mellon MT, Arvidson RE, Sizemore HG, Searls ML, Blaney DL, Cull S, Hecht MH, Heet TL, Keller HU, Lemmon MT, Markiewicz WJ, Ming DW, Morris RV, Pike WT, Zent AP. Ground ice at the Phoenix landing site: Stability state and origin Journal of Geophysical Research E: Planets. 114. DOI: 10.1029/2009JE003417  0.32
2009 Kounaves SP, Hecht MH, West SJ, Morookian JM, Young SMM, Quinn R, Grunthaner P, Wen X, Weilert M, Cable CA, Fisher A, Gospodinova K, Kapit J, Stroble S, Hsu PC, et al. The MECA wet chemistry laboratory on the 2007 Phoenix Mars Scout Lander Journal of Geophysical Research E: Planets. 114. DOI: 10.1029/2008JE003084  0.32
2009 Hecht MH, Marshall J, Pike WT, Staufer U, Blaney D, Braendlin D, Gautsch S, Goetz W, Hidber HR, Keller HU, Markiewicz WJ, Mazer A, Meloy TP, Morookian JM, Mogensen C, et al. Microscopy capabilities of the microscopy, electrochemistry, and conductivity analyzer Journal of Geophysical Research E: Planets. 114. DOI: 10.1029/2008JE003077  0.32
2009 Zent AP, Hecht MH, Cobos DR, Campbell GS, Campbell CS, Cardell G, Foote MC, Wood SE, Mehta M. Thermal and Electrical Conductivity Probe (TECP) for phoenix Journal of Geophysical Research E: Planets. 114. DOI: 10.1029/2007JE003052  0.32
2009 Leer K, Bertelsen P, Binau CS, Djernis Olsen L, Drube L, Falkenberg TV, Haspang MP, Madsen MB, Olsen M, Sykulska H, Vijendran S, Pike WT, Staufer U, Parrat D, Lemmon M, ... Hecht MH, et al. Magnetic properties experiments and the Surface Stereo Imager calibration target onboard the Mars Phoenix 2007 Lander: Design, calibration, and science goals Journal of Geophysical Research E: Planets. 114. DOI: 10.1029/2007JE003014  0.32
2008 Go A, Kim S, Baum J, Hecht MH. Structure and dynamics of de novo proteins from a designed superfamily of 4-helix bundles. Protein Science : a Publication of the Protein Society. 17: 821-32. PMID 18436954 DOI: 10.1110/ps.073377908  1
2008 Kim W, Hecht MH. Mutations enhance the aggregation propensity of the Alzheimer's A beta peptide. Journal of Molecular Biology. 377: 565-74. PMID 18258258 DOI: 10.1016/j.jmb.2007.12.079  1
2008 Hecht MH. The texture of condensed CO2 on the martian polar caps Planetary and Space Science. 56: 246-250. DOI: 10.1016/j.pss.2007.08.009  0.32
2007 Go A, Kim S, Hecht M, Baum J. NMR assignment of S836: A de novo protein from a designed superfamily Biomolecular Nmr Assignments. 1: 213-215. PMID 19636868 DOI: 10.1007/s12104-007-9059-3  1
2007 Das A, Hecht MH. Peroxidase activity of de novo heme proteins immobilized on electrodes. Journal of Inorganic Biochemistry. 101: 1820-6. PMID 17765314 DOI: 10.1016/j.jinorgbio.2007.07.024  1
2007 Bradley LH, Wei Y, Thumfort P, Wurth C, Hecht MH. Protein design by binary patterning of polar and nonpolar amino acids. Methods in Molecular Biology (Clifton, N.J.). 352: 155-66. PMID 17041264 DOI: 10.1385/1-59745-187-8:155  1
2007 Hudson TL, Aharonson O, Schorghofer N, Farmer CB, Hecht MH, Bridges NT. Water vapor diffusion in Mars subsurface environments Journal of Geophysical Research E: Planets. 112. DOI: 10.1029/2006JE002815  0.32
2007 Dismukes GC, Hecht M, Chianelli RR, Spiro TG, Groves JT. Remembering Edward I. Stiefel Journal of Inorganic Biochemistry. 101: vii-viii. DOI: 10.1016/j.jinorgbio.2006.11.022  1
2006 Kim W, Kim Y, Min J, Kim DJ, Chang YT, Hecht MH. A high-throughput screen for compounds that inhibit aggregation of the Alzheimer's peptide. Acs Chemical Biology. 1: 461-9. PMID 17168524 DOI: 10.1021/cb600135w  1
2006 Kim W, Hecht MH. Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Abeta42 peptide. Proceedings of the National Academy of Sciences of the United States of America. 103: 15824-9. PMID 17038501 DOI: 10.1073/pnas.0605629103  1
2006 Bradley LH, Thumfort PP, Hecht MH. De novo proteins from binary-patterned combinatorial libraries. Methods in Molecular Biology (Clifton, N.J.). 340: 53-69. PMID 16957332 DOI: 10.1385/1-59745-116-9:53  1
2006 Das A, Trammell SA, Hecht MH. Electrochemical and ligand binding studies of a de novo heme protein. Biophysical Chemistry. 123: 102-12. PMID 16730114 DOI: 10.1016/j.bpc.2006.04.011  1
2006 Wurth C, Kim W, Hecht MH. Combinatorial approaches to probe the sequence determinants of protein aggregation and amyloidogenicity. Protein and Peptide Letters. 13: 279-86. PMID 16515456 DOI: 10.2174/092986606775338506  1
2006 Taylor PA, Baibakov K, Brown S, Hecht MH, Hudson TL, Li PY, Lange CF, Prieto L, Savelyev S. On the sublimation of ice particles on the surface of Mars; with applications to the 2007/8 Phoenix Scout mission Icarus. 181: 375-387. DOI: 10.1016/j.icarus.2005.10.031  0.32
2005 Hu Y, Das A, Hecht MH, Scoles G. Nanografting de novo proteins onto gold surfaces. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 9103-9. PMID 16171339 DOI: 10.1021/la046857h  1
2005 Kim W, Hecht MH. Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40. The Journal of Biological Chemistry. 280: 35069-76. PMID 16079141 DOI: 10.1074/jbc.M505763200  1
2005 Bradley LH, Kleiner RE, Wang AF, Hecht MH, Wood DW. An intein-based genetic selection allows the construction of a high-quality library of binary patterned de novo protein sequences. Protein Engineering, Design & Selection : Peds. 18: 201-7. PMID 15849217 DOI: 10.1093/protein/gzi020  1
2005 Klepeis JL, Wei Y, Hecht MH, Floudas CA. Ab initio prediction of the three-dimensional structure of a de novo designed protein: a double-blind case study. Proteins. 58: 560-70. PMID 15609306 DOI: 10.1002/prot.20338  1
2004 Hecht MH, Das A, Go A, Bradley LH, Wei Y. De novo proteins from designed combinatorial libraries. Protein Science : a Publication of the Protein Society. 13: 1711-23. PMID 15215517 DOI: 10.1110/ps.04690804  1
2004 Wei Y, Hecht MH. Enzyme-like proteins from an unselected library of designed amino acid sequences. Protein Engineering, Design & Selection : Peds. 17: 67-75. PMID 14985539 DOI: 10.1093/protein/gzh007  1
2004 Towner MC, Patel MR, Ringrose TJ, Zarnecki JC, Pullan D, Sims MR, Haapanala S, Harri AM, Polkko J, Wilson CF, Zent AP, Quinn RC, Grunthaner FJ, Hecht MH, Garry JRC. The Beagle 2 environmental sensors: Science goals and instrument description Planetary and Space Science. 52: 1141-1156. DOI: 10.1016/j.pss.2004.07.015  0.32
2003 Kounaves SP, Lukow SR, Comeau BP, Hecht MH, Grannan-Feldman SM, Manatt K, West SJ, Wen X, Frant M, Gillette T. Mars Surveyor Program '01 Mars Environmental Compatibility Assessment wet chemistry lab: a sensor array for chemical analysis of the Martian soil. Journal of Geophysical Research. 108: 13-1 - 13-12. PMID 14686320  0.32
2003 Wei Y, Kim S, Fela D, Baum J, Hecht MH. Solution structure of a de novo protein from a designed combinatorial library. Proceedings of the National Academy of Sciences of the United States of America. 100: 13270-3. PMID 14593201 DOI: 10.1073/pnas.1835644100  1
2003 Wei Y, Fela D, Kim S, Hecht M, Baum J. 1H, 13C and 15N resonance assignments of S-824, a de novo four-helix bundle from a designed combinatorial library. Journal of Biomolecular Nmr. 27: 395-6. PMID 14512738 DOI: 10.1023/A:1025842221022  1
2003 Moffet DA, Foley J, Hecht MH. Midpoint reduction potentials and heme binding stoichiometries of de novo proteins from designed combinatorial libraries. Biophysical Chemistry. 105: 231-9. PMID 14499895 DOI: 10.1016/S0301-4622(03)00072-3  1
2003 Wei Y, Liu T, Sazinsky SL, Moffet DA, Pelczer I, Hecht MH. Stably folded de novo proteins from a designed combinatorial library. Protein Science : a Publication of the Protein Society. 12: 92-102. PMID 12493832 DOI: 10.1110/ps.0228003  1
2003 Cooper LP, Hecht MH, Majchrzak A. Managing a project's legacy: Implications for organizations and project management Ieee Aerospace Conference Proceedings. 8: 3793-3800. DOI: 10.1109/AERO.2003.1235564  0.32
2003 Zent AP, Quinn RC, Grunthaner FJ, Hecht MH, Buehler MG, McKay CP, Ricco AJ. Mars atmospheric oxidant sensor (MAOS): An in-situ heterogeneous chemistry analysis Planetary and Space Science. 51: 167-175. DOI: 10.1016/S0032-0633(02)00204-0  0.32
2003 Tratt DM, Hecht MH, Catling DC, Samulon EC, Smith PH. In situ measurement of dust devil dynamics: Toward a strategy for Mars Journal of Geophysical Research E: Planets. 108: 2-1.  0.32
2002 Wurth C, Guimard NK, Hecht MH. Mutations that reduce aggregation of the Alzheimer's Abeta42 peptide: an unbiased search for the sequence determinants of Abeta amyloidogenesis. Journal of Molecular Biology. 319: 1279-90. PMID 12079364 DOI: 10.1016/S0022-2836(02)00399-6  1
2002 Brown CL, Aksay IA, Saville DA, Hecht MH. Template-directed assembly of a de novo designed protein. Journal of the American Chemical Society. 124: 6846-8. PMID 12059204 DOI: 10.1021/ja0261271  1
2002 Wu Q, Li F, Wang W, Hecht MH, Spiro TG. UV Raman monitoring of histidine protonation and H-(2)H exchange in plastocyanin. Journal of Inorganic Biochemistry. 88: 381-7. PMID 11897354 DOI: 10.1016/S0162-0134(01)00354-3  1
2002 Wang W, Hecht MH. Rationally designed mutations convert de novo amyloid-like fibrils into monomeric beta-sheet proteins. Proceedings of the National Academy of Sciences of the United States of America. 99: 2760-5. PMID 11880628 DOI: 10.1073/pnas.052706199  1
2002 Hecht MH. Aqueous environments on contemporary Mars? Proceedings of Spie - the International Society For Optical Engineering. 4495: 69-80. DOI: 10.1117/12.454777  0.32
2002 Kounaves SP, Noll RA, Buehler MG, Hecht MH, Lankford K, West SJ. Microbial life detection with minimal assumptions Proceedings of Spie - the International Society For Optical Engineering. 4495: 137-144. DOI: 10.1117/12.454772  0.32
2002 Kuhlman KR, Hecht MH, Brinza DE, Feldman JE, Fuerstenau SD, Friedman L, Kelly L, Oslick J, Polk K, Moller LE, Trowbridge K, Sherman J, Marshall A, Diaz AL, Waldron A, et al. SNOOPY: Student nanoexperiments for outreach and observational planetary inquiry Ieee Aerospace Conference Proceedings. 1: 317-325. DOI: 10.1109/AERO.2002.1036851  0.32
2002 Hecht MH. Metastability of liquid water on Mars Icarus. 156: 373-386. DOI: 10.1006/icar.2001.6794  0.32
2002 Kounaves SP, Buehler MG, Hecht MH, West S. Determination of Geochemistry on Mars Using an Array of Electrochemical Sensors Acs Symposium Series. 811: 306-319.  0.32
2001 Moffet DA, Hecht MH. De novo proteins from combinatorial libraries. Chemical Reviews. 101: 3191-203. PMID 11710068 DOI: 10.1021/cr000051e  1
2001 Moffet DA, Case MA, House JC, Vogel K, Williams RD, Spiro TG, McLendon GL, Hecht MH. Carbon monoxide binding by de novo heme proteins derived from designed combinatorial libraries. Journal of the American Chemical Society. 123: 2109-15. PMID 11456855 DOI: 10.1021/ja0036007  1
2001 Xu G, Wang W, Groves JT, Hecht MH. Self-assembled monolayers from a designed combinatorial library of de novo beta-sheet proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 3652-7. PMID 11274383 DOI: 10.1073/pnas.071400098  1
2001 Akiyama T, Gautsch S, De Rooij NF, Staufer U, Niedermann P, Howald L, Müller D, Tonin A, Hidber HR, Pike WT, Hecht MH. Atomic force microscope for planetary applications Sensors and Actuators, a: Physical. 90: 321-325.  0.32
2000 Yen AS, Kim SS, Hecht MH, Frant MS, Murray B. Evidence that the reactivity of the martian soil is due to superoxide ions. Science (New York, N.Y.). 289: 1909-12. PMID 10988066 DOI: 10.1126/science.289.5486.1909  0.32
2000 Roy S, Hecht MH. Cooperative thermal denaturation of proteins designed by binary patterning of polar and nonpolar amino acids. Biochemistry. 39: 4603-7. PMID 10769115 DOI: 10.1021/bi992328e  1
2000 Broome BM, Hecht MH. Nature disfavors sequences of alternating polar and non-polar amino acids: implications for amyloidogenesis. Journal of Molecular Biology. 296: 961-8. PMID 10686095 DOI: 10.1006/jmbi.2000.3514  1
2000 Moffet DA, Certain LK, Smith AJ, Kessel AJ, Beckwith KA, Hecht MH. Peroxidase activity in heme proteins derived from a designed combinatorial library [11] Journal of the American Chemical Society. 122: 7612-7613. DOI: 10.1021/ja001198q  1
1999 West SJ, Frant MS, Wen X, Geis R, Herdan J, Gillette T, Hecht MH, Schubert W, Grannan S, Kounaves SP. Electrochemistry on Mars. American Laboratory. 31: 48-54. PMID 11543343  0.32
1999 West MW, Wang W, Patterson J, Mancias JD, Beasley JR, Hecht MH. De novo amyloid proteins from designed combinatorial libraries. Proceedings of the National Academy of Sciences of the United States of America. 96: 11211-6. PMID 10500156 DOI: 10.1073/pnas.96.20.11211  1
1999 Dong S, Ybe JA, Hecht MH, Spiro TG. H-bonding maintains the active site of type 1 copper proteins: site-directed mutagenesis of Asn38 in poplar plastocyanin. Biochemistry. 38: 3379-85. PMID 10079082 DOI: 10.1021/bi981999u  1
1999 Rosenbaum DM, Roy S, Hecht MH. Screening combinatorial libraries of de Novo proteins by hydrogen- deuterium exchange and electrospray mass spectrometry Journal of the American Chemical Society. 121: 9509-9513. DOI: 10.1021/ja991843x  1
1999 Reynolds JK, Catling DC, Blue RC, Hecht MH, Maluf N, Kenny TW. Packaging of micromachined absolute pressure sensors for high-accuracy measurements American Society of Mechanical Engineers, Eep. 26: 1/-.  0.32
1997 Rojas NR, Kamtekar S, Simons CT, McLean JE, Vogel KM, Spiro TG, Farid RS, Hecht MH. De novo heme proteins from designed combinatorial libraries. Protein Science : a Publication of the Protein Society. 6: 2512-24. PMID 9416601 DOI: 10.1002/pro.5560061204  1
1997 Nedwidek MN, Hecht MH. Minimized protein structures: a little goes a long way. Proceedings of the National Academy of Sciences of the United States of America. 94: 10010-1. PMID 9294152 DOI: 10.1073/pnas.94.19.10010  1
1997 Roy S, Helmer KJ, Hecht MH. Detecting native-like properties in combinatorial libraries of de novo proteins. Folding & Design. 2: 89-92. PMID 9135980 DOI: 10.1016/S1359-0278(97)00012-6  1
1997 Beasley JR, Hecht MH. Protein design: the choice of de novo sequences. The Journal of Biological Chemistry. 272: 2031-4. PMID 9036150 DOI: 10.1074/jbc.272.4.2031  1
1997 Roy S, Ratnaswamy G, Boice JA, Fairman R, McLendon G, Hecht MH. A protein designed by binary patterning of polar and nonpolar amino acids displays native-like properties Journal of the American Chemical Society. 119: 5302-5306. DOI: 10.1021/ja9700717  1
1997 Hecht MH, West MW, Roy S, Rojas NR, Kamtekar S, McLean J, Helmer KJ, Simons CT, Beasley JR. Design of libraries of De Nova proteins by binary patterning of polar and nonpolar amino acids Protein Engineering. 10: 20.  1
1997 Rojas NRL, Kamtekar S, Simons CT, McLean J, Hecht MH. Heme binding in a library of de Novo designed α-helical binary code proteins Protein Engineering. 10: 35.  1
1997 West MW, Beasley JR, Hecht MH. Collection's of de Novo beta-sheet proteins designed by binary patterning of polar and nonpolar amino acids Protein Engineering. 10: 38.  1
1997 Brennen RA, Hecht MH, Wiberg DV, Manion SJ, Bonivert WD, Hruby JM, Scholz ML, Stowe TD, Kenny TW, Jackson KH, Malek CK. Fabrication of collimating grids for an x-ray solar telescope using LIGA methods Microsystem Technologies. 3: 91-96.  0.32
1996 Ybe JA, Hecht MH. Sequence replacements in the central beta-turn of plastocyanin. Protein Science : a Publication of the Protein Society. 5: 814-24. PMID 8732753 DOI: 10.1002/pro.5560050503  1
1996 Buehler MG, Bell LD, Hecht MH. Alpha-particle gas-pressure sensor Journal of Vacuum Science and Technology a: Vacuum, Surfaces and Films. 14: 1281-1287.  0.32
1995 West MW, Hecht MH. Binary patterning of polar and nonpolar amino acids in the sequences and structures of native proteins. Protein Science : a Publication of the Protein Society. 4: 2032-9. PMID 8535239 DOI: 10.1002/pro.5560041008  1
1995 Kamtekar S, Hecht MH. Protein Motifs. 7. The four-helix bundle: what determines a fold? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1013-22. PMID 7649401  1
1995 Xiong H, Buckwalter BL, Shieh HM, Hecht MH. Periodicity of polar and nonpolar amino acids is the major determinant of secondary structure in self-assembling oligomeric peptides. Proceedings of the National Academy of Sciences of the United States of America. 92: 6349-53. PMID 7603994 DOI: 10.1073/pnas.92.14.6349  1
1995 Qiu D, Dong S, Ybe JA, Hecht MH, Spiro TG. Variations in the type I copper protein coordination group: Resonance Raman spectrum of 34S-, 65Cu-, and 15N-labeled plastocyanin Journal of the American Chemical Society. 117: 6443-6446.  1
1994 Hecht MH. De novo design of beta-sheet proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 8729-30. PMID 8090714 DOI: 10.1073/pnas.91.19.8729  1
1994 Ybe JA, Hecht MH. Periplasmic fractionation of Escherichia coli yields recombinant plastocyanin despite the absence of a signal sequence. Protein Expression and Purification. 5: 317-23. PMID 7950377 DOI: 10.1006/prep.1994.1047  1
1994 Johnson BH, Hecht MH. Recombinant proteins can be isolated from E. coli cells by repeated cycles of freezing and thawing. Bio/Technology (Nature Publishing Company). 12: 1357-60. PMID 7765566 DOI: 10.1038/nbt1294-1357  1
1993 Bell LD, Manion SJ, Hecht MH, Kaiser WJ, Fathauer RW, Milliken AM. Characterizing hot-carrier transport in silicon heterostructures with the use of ballistic-electron-emission microscopy. Physical Review. B, Condensed Matter. 48: 5712-5715. PMID 10009102 DOI: 10.1103/PhysRevB.48.5712  0.32
1993 Kaiser WJ, Hecht MH, Bell LD, Grunthaner FJ, Liu JK, Davis LC. Ballistic-electron-emission microscopy of electron transport through AlAs/GaAs heterostructures. Physical Review. B, Condensed Matter. 48: 18324-18327. PMID 10008486 DOI: 10.1103/PhysRevB.48.18324  0.32
1993 Brunet AP, Huang ES, Huffine ME, Loeb JE, Weltman RJ, Hecht MH. The role of turns in the structure of an alpha-helical protein. Nature. 364: 355-8. PMID 8332196 DOI: 10.1038/364355a0  1
1993 Kamtekar S, Schiffer JM, Xiong H, Babik JM, Hecht MH. Protein design by binary patterning of polar and nonpolar amino acids. Science (New York, N.Y.). 262: 1680-5. PMID 8259512  1
1993 Bell LD, Kaiser WJ, Hecht MH, Davis LC. 7. Ballistic Electron Emission Microscopy Methods in Experimental Physics. 27: 307-348. DOI: 10.1016/S0076-695X(08)60014-9  0.32
1992 Milliken AM, Manion SJ, Kaiser WJ, Bell LD, Hecht MH. Probing hot-carrier transport and elastic scattering using ballistic-electron-emission microscopy. Physical Review. B, Condensed Matter. 46: 12826-12829. PMID 10003219 DOI: 10.1103/PhysRevB.46.12826  0.32
1992 Richardson JS, Richardson DC, Tweedy NB, Gernert KM, Quinn TP, Hecht MH, Erickson BW, Yan Y, McClain RD, Donlan ME. Looking at proteins: representations, folding, packing, and design. Biophysical Society National Lecture, 1992. Biophysical Journal. 63: 1185-209. PMID 1477272  1
1991 Kaiser WJ, Hecht MH, Fathauer RW, Bell LD, Lee EY, Davis LC. Ballistic-carrier spectroscopy of the CoSi2/Si interface. Physical Review. B, Condensed Matter. 44: 6546-6549. PMID 9998525 DOI: 10.1103/PhysRevB.44.6546  0.32
1991 Hecht MH. Time dependence of photovoltaic shifts in photoelectron spectroscopy of semiconductors. Physical Review. B, Condensed Matter. 43: 12102-12105. PMID 9997001 DOI: 10.1103/PhysRevB.43.12102  0.32
1990 Bell LD, Hecht MH, Kaiser WJ, Davis LC. Direct spectroscopy of electron and hole scattering. Physical Review Letters. 64: 2679-2682. PMID 10041782 DOI: 10.1103/PhysRevLett.64.2679  0.32
1990 Hecht MH, Bell LD, Kaiser WJ, Davis LC. Ballistic-hole spectroscopy of interfaces. Physical Review. B, Condensed Matter. 42: 7663-7666. PMID 9994923 DOI: 10.1103/PhysRevB.42.7663  0.32
1990 Chang S, Vitomirov IM, Brillson LJ, Rioux DF, Kirchner PD, Pettit GD, Woodall JM, Hecht MH. Confirmation of the temperature-dependent photovoltaic effect on Fermi-level measurements by photoemission spectroscopy. Physical Review. B, Condensed Matter. 41: 12299-12302. PMID 9993693 DOI: 10.1103/PhysRevB.41.12299  0.32
1990 Hecht MH. Role of photocurrent in low-temperature photoemission studies of Schottky-barrier formation. Physical Review. B, Condensed Matter. 41: 7918-7921. PMID 9993103 DOI: 10.1103/PhysRevB.41.7918  0.32
1990 Hecht MH, Richardson JS, Richardson DC, Ogden RC. De novo design, expression, and characterization of Felix: a four-helix bundle protein of native-like sequence. Science (New York, N.Y.). 249: 884-91. PMID 2392678  1
1989 Hecht MH, Bell LD, Kaiser WJ, Grunthaner FJ. Ballistic-electron-emission microscopy investigation of Schottky barrier interface formation Applied Physics Letters. 55: 780-782. DOI: 10.1063/1.101778  0.32
1989 Hecht MH, Orient OJ, Chutjian A, Vasquez RP. Oxidation of silicon with a 5 eV O- beam Applied Physics Letters. 54: 421-423. DOI: 10.1063/1.101456  0.32
1989 Hecht MH, Bell LD, Kaiser WJ. Ballistic-electron-emission microscopy of subsurface defects at the Au-GaAs(100) interface Applied Surface Science. 41: 17-24. DOI: 10.1016/0169-4332(89)90027-5  0.32
1989 Grunthaner PJ, Grunthaner FJ, Fathauer RW, Lin TL, Hecht MH, Bell LD, Kaiser WJ, Schowengerdt FD, Mazur JH. Hydrogen-terminated silicon substrates for low-temperature molecular beam epitaxy Thin Solid Films. 183: 197-212. DOI: 10.1016/0040-6090(89)90445-8  0.32
1988 Kaiser WJ, bell LD, Hecht MH, Grunthaner FJ. Scanning tunneling microscopy characterization of the geometric and electronic structure of hydrogen-terminated silicon surfaces Journal of Vacuum Science and Technology a: Vacuum, Surfaces and Films. 6: 519-523. DOI: 10.1116/1.575372  0.32
1988 Bell LD, Kaiser WJ, Hecht MH, Grunthaner FJ. Direct control and characterization of a Schottky barrier by scanning tunneling microscopy Applied Physics Letters. 52: 278-280. DOI: 10.1063/1.99493  0.32
1988 Kaiser WJ, Bell LD, Hecht MH, LeDuc HG, Stern JA. SCANNING TUNNELING MICROSCOPY: TOPOGRAPHIC AND SPECTROSCOPIC STUDIES OF SURFACES Journal of Molecular Electronics. 4: 402.  0.32
1987 Grunthaner PJ, Hecht MH, Grunthaner FJ, Johnson NM. The localization and crystallographic dependence of Si suboxide species at the SiO2/Si interface Journal of Applied Physics. 61: 629-638. DOI: 10.1063/1.338215  0.32
1986 Hecht MH, Sturtevant JM, Sauer RT. Stabilization of lambda repressor against thermal denaturation by site-directed Gly----Ala changes in alpha-helix 3. Proteins. 1: 43-6. PMID 3449850 DOI: 10.1002/prot.340010108  1
1986 Hecht MH, Grunthaner FJ, Pate BB, Pianetta P, Engelhardt M, Jansen W, Bryson C. Soft X-ray photoemission with the SSX-100 spectrometer Nuclear Inst. and Methods in Physics Research, A. 246: 806-809. DOI: 10.1016/0168-9002(86)90198-1  0.32
1986 Grunthaner FJ, Grunthaner PJ, Hecht MH, Lawson D. CHEMICAL STRUCTURE OF THE SiO//2/Si INTERFACE AS DETERMINED BY HIGH RESOLUTION XPS: SUBOXIDE DISTRIBUTIONS AND THE FORMATION OF ELECTRICALLY ACTIVE INTERFACE STATES . 1-10.  0.32
1985 Hecht MH, Hehir KM, Nelson HC, Sturtevant JM, Sauer RT. Increasing and decreasing protein stability: effects of revertant substitutions on the thermal denaturation of phage lambda repressor. Journal of Cellular Biochemistry. 29: 217-24. PMID 4077930 DOI: 10.1002/jcb.240290306  1
1985 Hecht MH, Sauer RT. Phage lambda repressor revertants. Amino acid substitutions that restore activity to mutant proteins. Journal of Molecular Biology. 186: 53-63. PMID 2934554 DOI: 10.1016/0022-2836(85)90256-6  1
1985 Hecht MH, Grunthaner FJ. Studies of the Si/SiO2 interface using synchrotron radiation Proceedings of Spie - the International Society For Optical Engineering. 524: 18-24. DOI: 10.1117/12.946315  0.32
1985 Hecht MH, Vasquez RP, Grunthaner FJ, Zamani N, Maserjian J. A novel x-ray photoelectron spectroscopy study of the Al/SiO2 interface Journal of Applied Physics. 57: 5256-5261. DOI: 10.1063/1.335266  0.32
1985 Hecht MH, Lindau I. The energy dependence of photoelectron peak intensities, Part I: Experimental methods Journal of Electron Spectroscopy and Related Phenomena. 35: 211-237. DOI: 10.1016/0368-2048(85)80058-X  0.32
1984 Hecht MH, Sturtevant JM, Sauer RT. Effect of single amino acid replacements on the thermal stability of the NH2-terminal domain of phage lambda repressor. Proceedings of the National Academy of Sciences of the United States of America. 81: 5685-9. PMID 6237363  1
1984 Hecht MH, Grunthaner FJ, Pianetta P, Lindau I, Johansson LI. Electron Escape Depth Variation in thin Si02 Films Measured with Variable Photon Energy Journal of Vacuum Science and Technology a: Vacuum, Surfaces and Films. 2: 584-587. DOI: 10.1116/1.572450  0.32
1984 Rothberg GM, Choudhary KM, Denboer ML, Williams GP, Hecht MH, Lindau I. Extended x-ray absorption fine structure in photoelectron emission Physical Review Letters. 53: 1183-1186. DOI: 10.1103/PhysRevLett.53.1183  0.32
1984 Vasquez RP, Hecht MH, Grunthaner FJ, Naiman ML. X-ray photoelectron spectroscopy study of the chemical structure of thermally nitrided SiO2 Applied Physics Letters. 44: 969-971. DOI: 10.1063/1.94614  0.32
1984 Hecht MH, Viescas AJ, Lindau I, Allen JW, Johansson LI. Intrinsic surface binding energy shifts in Yb metal Journal of Electron Spectroscopy and Related Phenomena. 34: 343-353. DOI: 10.1016/0368-2048(84)80048-1  0.32
1984 Hecht MH, Grunthauer FJ, Maserjian J. XPS STUDY OF THE Al/SiO//2 INTERFACE VIEWED FROM THE SiO//2 SIDE Materials Research Society Symposia Proceedings. 25: 317-322.  0.32
1983 Sauer RT, Nelson HC, Hehir K, Hecht MH, Gimble FS, DeAnda J, Poteete AR. The lambda and P22 phage repressors. Journal of Biomolecular Structure & Dynamics. 1: 1011-22. PMID 6242868 DOI: 10.1080/07391102.1983.10507499  1
1983 Nelson HC, Hecht MH, Sauer RT. Mutations defining the operator-binding sites of bacteriophage lambda repressor. Cold Spring Harbor Symposia On Quantitative Biology. 47: 441-9. PMID 6222865  1
1983 Hecht MH, Nelson HC, Sauer RT. Mutations in lambda repressor's amino-terminal domain: implications for protein stability and DNA binding. Proceedings of the National Academy of Sciences of the United States of America. 80: 2676-80. PMID 6221342  1
1983 Pate BB, Waclawski BJ, Stefan PM, Binns C, Ohta T, Hecht MH, Jupiter PJ, Shek ML, Pierce DT, Swanson N, Celotta RJ, Rossi G, Lindau I, Spicer WE. The diamond (111) surface: A dilemma resolved Physica B+C. 117: 783-785. DOI: 10.1016/0378-4363(83)90652-6  0.32
1983 Hecht MH, Bringans RD, Lindau I, Bachrach RZ. Modelling a soft X-ray wunder Nuclear Instruments and Methods in Physics Research. 208: 113-116. DOI: 10.1016/0167-5087(83)91110-9  0.32
1983 Bachrach RZ, Swartz LE, Hagstrom SB, Lindau I, Hecht MH, Spicer WE. SSRL beam line wunder: Design and planning Nuclear Instruments and Methods in Physics Research. 208: 105-112. DOI: 10.1016/0167-5087(83)91109-2  0.32
1982 Hecht MH, Lindau I, Chen DS. Oxidation studies of impregnated dispenser cathodes Journal of Applied Physics. 53: 9021-9028. DOI: 10.1063/1.330410  0.32
1982 Chen DS, Lindau I, Hecht MH, Viescas AJ, Nogami J, Spicer WE. Surface studies of the tungsten dispenser cathode Applications of Surface Science. 13: 321-328. DOI: 10.1016/0378-5963(82)90001-0  0.32
1982 Hecht MH, Lindau I. Measurement of transmission of VUV monochromators and electron spectrometers using photoemission spectroscopy Nuclear Instruments and Methods. 195: 339-342. DOI: 10.1016/0029-554X(82)90794-7  0.32
1982 PATE BB, HECHT MH, BINNS C, LINDAU I, SPICER WE. PHOTOEMISSION AND PHOTON-STIMULATED ION DESORPTION STUDIES OF DIAMOND(111): HYDROGEN J Vac Sci Technol. 364-367.  0.32
1982 Pate BB, Waclawski BJ, Stefan PM, Binns C, Ohta T, Hecht MH, Jupiter PJ, Shek ML, Pierce DT, Swanson N, Celotta RJ, Rossi G, Lindau I, Spicer WE. DIAMOND (111) SURFACE: A DILEMMA RESOLVED Physica B: Physics of Condensed Matter & C: Atomic, Molecular and Plasma Physics, Optics. 117: 783-785.  0.32
1981 Hecht MH, Lindau I. Measurement of subshell photoionization cross sections of Ba near the 4d threshold Physical Review Letters. 47: 821-824. DOI: 10.1103/PhysRevLett.47.821  0.32
1981 Egelhoff WF, Tibbetts GG, Hecht MH, Lindau I. Determination of the decay channel of the 4d 4f Resonance in Tm Physical Review Letters. 46: 1071-1074. DOI: 10.1103/PhysRevLett.46.1071  0.32
1980 Johansson LI, Allen JW, Lindau I, Hecht MH, Hagström SBM. Photoemission from Yb: Valence-change-induced Fano resonance Physical Review B. 21: 1408-1411. DOI: 10.1103/PhysRevB.21.1408  0.32
1980 Johansson LI, Hecht MH, Lindau I. The energy-dependence of the Au 4f photoionization cross-section Journal of Electron Spectroscopy and Related Phenomena. 18: 271-274. DOI: 10.1016/0368-2048(80)80053-3  0.32
1980 Johansson LI, Lindau I, Hecht MH, Källne E. Photoelectron branching ratio in the 5d subshell of Pt, Au and Pb measured with synchrotron radiation Solid State Communications. 34: 83-86. DOI: 10.1016/0038-1098(80)91238-7  0.32
1978 Hecht MH, Zweifel BO, Scheraga HA. Helix-coil stability constants for the naturally occurring amino acids in water. 17. Threonine parameters from random poly(hydroxybutylglutamine-co- L-threonine) Macromolecules. 11: 545-551.  0.84
1978 Hecht MH, Lindau I, Johansson LI. EXPERIMENTAL VERIFICATION OF MANY-ELECTRON EFFECTS IN THE 4d, 5s, AND 5p PARTIAL PHOTOIONIZATION CROSS SECTIONS OF Cs Japanese Journal of Applied Physics. 17: 249-251.  0.32
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