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Ariel R. Topletz, Ph.D. - Publications

Affiliations: 
2013 Pharmaceutics University of Washington, Seattle, Seattle, WA 
Area:
Pharmacy
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Topletz AR, Zhong G, Isoherranen N. Scaling in vitro activity of CYP3A7 suggests human fetal livers do not clear retinoic acid entering from maternal circulation. Scientific Reports. 9: 4620. PMID 30874620 DOI: 10.1038/S41598-019-40995-8  0.562
2017 Jing J, Petroff R, Shum S, Crouthamel B, Topletz AR, Grant KS, Burbacher TM, Isoherranen N. Toxicokinetics and Physiologically Based Pharmacokinetic Modeling of the Shellfish Toxin Domoic Acid in Nonhuman Primates. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29150543 DOI: 10.1124/Dmd.117.078485  0.449
2015 Topletz AR, Tripathy S, Foti RS, Shimshoni JA, Nelson WL, Isoherranen N. Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. Molecular Pharmacology. 87: 430-41. PMID 25492813 DOI: 10.1124/Mol.114.096784  0.568
2013 Topletz AR, Dennison JB, Barbuch RJ, Hadden CE, Hall SD, Renbarger JL. The relative contributions of CYP3A4 and CYP3A5 to the metabolism of vinorelbine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1651-61. PMID 23780963 DOI: 10.1124/dmd.113.051094  0.357
2013 Topletz AR, Le HN, Lee N, Chapman JD, Kelly EJ, Wang J, Isoherranen N. Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 312-9. PMID 23150428 DOI: 10.1124/Dmd.112.049379  0.535
2012 Shimshoni JA, Roberts AG, Scian M, Topletz AR, Blankert SA, Halpert JR, Nelson WL, Isoherranen N. Stereoselective formation and metabolism of 4-hydroxy-retinoic Acid enantiomers by cytochrome p450 enzymes. The Journal of Biological Chemistry. 287: 42223-32. PMID 23071109 DOI: 10.1074/Jbc.M112.404475  0.527
2012 Topletz AR, Thatcher JE, Zelter A, Lutz JD, Tay S, Nelson WL, Isoherranen N. Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases. Biochemical Pharmacology. 83: 149-63. PMID 22020119 DOI: 10.1016/J.Bcp.2011.10.007  0.59
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