Achim Brinker - Publications

Affiliations: 
2003- Scripps Research Institute 

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Johnson SM, Sharif O, Mak PA, Wang HT, Engels IH, Brinker A, Schultz PG, Horwich AL, Chapman E. A biochemical screen for GroEL/GroES inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 786-9. PMID 24418775 DOI: 10.1016/j.bmcl.2013.12.100  0.72
2013 Ramadoss NS, Alumasa JN, Cheng L, Wang Y, Li S, Chambers BS, Chang H, Chatterjee AK, Brinker A, Engels IH, Keiler KC. Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity. Proceedings of the National Academy of Sciences of the United States of America. 110: 10282-7. PMID 23733947 DOI: 10.1073/pnas.1302816110  0.72
2011 Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, et al. Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells. Angewandte Chemie (International Ed. in English). 50: 5734-6. PMID 21547985 DOI: 10.1002/anie.201101042  0.72
2011 Nam TG, Lee J, Walker JR, Brinker A, Cho CY, Schultz PG. Identification and characterization of small-molecule inducers of fetal hemoglobin. Chemmedchem. 6: 777-80. PMID 21416611 DOI: 10.1002/cmdc.201000505  0.72
2011 Crowther GJ, Napuli AJ, Gilligan JH, Gagaring K, Borboa R, Francek C, Chen Z, Dagostino EF, Stockmyer JB, Wang Y, Rodenbough PP, Castaneda LJ, Leibly DJ, Bhandari J, Gelb MH, ... Brinker A, et al. Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds. Molecular and Biochemical Parasitology. 175: 21-9. PMID 20813141 DOI: 10.1016/j.molbiopara.2010.08.005  0.72
2010 O'Leary DA, Vargas L, Sharif O, Garcia ME, Sigal YJ, Chow SK, Schmedt C, Caldwell JS, Brinker A, Engels IH. HTS-Compatible Patient-Derived Cell-Based Assay to Identify Small Molecule Modulators of Aberrant Splicing in Myotonic Dystrophy Type 1. Current Chemical Genomics. 4: 9-18. PMID 20502647 DOI: 10.2174/1875397301004010009  0.72
2009 O'Leary DA, Sharif O, Anderson P, Tu B, Welch G, Zhou Y, Caldwell JS, Engels IH, Brinker A. Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening. Plos One. 4: e8348. PMID 20020055 DOI: 10.1371/journal.pone.0008348  0.44
2009 Sharif O, Hu H, Klock H, Hampton EN, Nigoghossian E, Knuth MW, Matzen J, Anderson P, Trager R, Uno T, Glynne RJ, Azarian SM, Caldwell JS, Brinker A. Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4. Analytical Biochemistry. 392: 162-8. PMID 19482004 DOI: 10.1016/j.ab.2009.05.038  0.52
2009 Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, Markoulaki S, Hanna J, Lairson LL, Charette BD, Bouchez LC, Bollong M, Kunick C, Brinker A, Cho CY, Schultz PG, et al. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America. 106: 8912-7. PMID 19447925 DOI: 10.1073/pnas.0903860106  0.72
2009 Engels IH, Daguia C, Huynh T, Urbina H, Buddenkotte J, Schumacher A, Caldwell JS, Brinker A. A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity. Analytical Biochemistry. 390: 85-7. PMID 19328766 DOI: 10.1016/j.ab.2009.03.035  0.4
2009 Zhou V, Gao X, Han S, Brinker A, Caldwell JS, Gu XJ. An intracellular conformational sensor assay for Abl T315I. Analytical Biochemistry. 385: 300-8. PMID 19059193 DOI: 10.1016/j.ab.2008.11.015  0.32
2008 Jia Y, Gu XJ, Brinker A, Warmuth M. Measuring the tyrosine kinase activity: a review of biochemical and cellular assay technologies. Expert Opinion On Drug Discovery. 3: 959-78. PMID 23484970 DOI: 10.1517/17460441.3.8.959  0.32
2008 Adams DG, Wang Y, Mak PA, Chyba J, Shalizi O, Matzen J, Anderson P, Smith TR, Garcia M, Welch GL, Claret EJ, Fink M, Orth AP, Caldwell JS, Brinker A. Cellular Ser/Thr-kinase assays using generic peptide substrates. Current Chemical Genomics. 1: 54-64. PMID 20161828 DOI: 10.2174/1875397300801010054  0.52
2008 Plouffe D, Brinker A, McNamara C, Henson K, Kato N, Kuhen K, Nagle A, Adrián F, Matzen JT, Anderson P, Nam TG, Gray NS, Chatterjee A, Janes J, Yan SF, et al. In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America. 105: 9059-64. PMID 18579783 DOI: 10.1073/pnas.0802982105  0.72
2008 Cellitti SE, Jones DH, Lagpacan L, Hao X, Zhang Q, Hu H, Brittain SM, Brinker A, Caldwell J, Bursulaya B, Spraggon G, Brock A, Ryu Y, Uno T, Schultz PG, et al. In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy Journal of the American Chemical Society. 130: 9268-9281. PMID 18576636 DOI: 10.1021/ja801602q  0.72
2006 Geierstanger BH, Saviranta P, Brinker A. Antibody microarrays using resonance light-scattering particles for detection. Methods in Molecular Biology (Clifton, N.J.). 328: 31-50. PMID 16785640 DOI: 10.1385/1-59745-026-X:31  0.88
2005 Wang Y, Klock H, Yin H, Wolff K, Bieza K, Niswonger K, Matzen J, Gunderson D, Hale J, Lesley S, Kuhen K, Caldwell J, Brinker A. Homogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities. Journal of Biomolecular Screening. 10: 456-62. PMID 16093555 DOI: 10.1177/1087057105275212  0.52
2005 Haab BB, Geierstanger BH, Michailidis G, Vitzthum F, Forrester S, Okon R, Saviranta P, Brinker A, Sorette M, Perlee L, Suresh S, Drwal G, Adkins JN, Omenn GS. Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: systematic variation between sample types and calibration of mass spectrometry data. Proteomics. 5: 3278-91. PMID 16038022 DOI: 10.1002/pmic.200401276  0.72
2005 Kreusch A, Han S, Brinker A, Zhou V, Choi HS, He Y, Lesley SA, Caldwell J, Gu XJ. Crystal structures of human HSP90α-complexed with dihydroxyphenylpyrazoles Bioorganic and Medicinal Chemistry Letters. 15: 1475-1478. PMID 15713410 DOI: 10.1016/j.bmcl.2004.12.087  0.72
2004 Saviranta P, Okon R, Brinker A, Warashina M, Eppinger J, Geierstanger BH. Evaluating sandwich immunoassays in microarray format in terms of the ambient analyte regime. Clinical Chemistry. 50: 1907-20. PMID 15308599 DOI: 10.1373/clinchem.2004.037929  0.88
2004 Zhou V, Han S, Brinker A, Klock H, Caldwell J, Gu XJ. A time-resolved fluorescence resonance energy transfer-based HTS assay and a surface plasmon resonance-based binding assay for heat shock protein 90 inhibitors. Analytical Biochemistry. 331: 349-57. PMID 15265741 DOI: 10.1016/j.ab.2004.04.011  0.52
2003 Ding S, Wu TY, Brinker A, Peters EC, Hur W, Gray NS, Schultz PG. Synthetic small molecules that control stem cell fate. Proceedings of the National Academy of Sciences of the United States of America. 100: 7632-7. PMID 12794184 DOI: 10.1073/pnas.0732087100  0.72
2003 Salomon AR, Ficarro SB, Brill LM, Brinker A, Phung QT, Ericson C, Sauer K, Brock A, Horn DM, Schultz PG, Peters EC. Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 100: 443-8. PMID 12522270 DOI: 10.1073/pnas.2436191100  0.72
2002 Okamoto K, Brinker A, Paschen SA, Moarefi I, Hayer-Hartl M, Neupert W, Brunner M. The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation. The Embo Journal. 21: 3659-71. PMID 12110579 DOI: 10.1093/emboj/cdf358  0.72
2002 Barral JM, Hutagalung AH, Brinker A, Hartl FU, Epstein HF. Role of the myosin assembly protein UNC-45 as a molecular chaperone for myosin. Science (New York, N.Y.). 295: 669-71. PMID 11809970 DOI: 10.1126/science.1066648  0.72
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