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David R. Corey - Publications

1990 University of California, Berkeley, Berkeley, CA 
 1992- Pharmacology University of Texas Southwestern Medical Center, Dallas, TX, United States 

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rong Z, Gong X, Hulleman JD, Corey DR, Mootha VV. Trinucleotide Repeat-Targeting dCas9 as a Therapeutic Strategy for Fuchs' Endothelial Corneal Dystrophy. Translational Vision Science & Technology. 9: 47. PMID 32934897 DOI: 10.1167/tvst.9.9.47  0.56
2020 Chu Y, Kilikevicius A, Liu J, Johnson KC, Yokota S, Corey DR. Argonaute binding within 3'-untranslated regions poorly predicts gene repression. Nucleic Acids Research. PMID 32501500 DOI: 10.1093/nar/gkaa478  1
2020 Chu Y, Hu J, Liang H, Kanchwala M, Xing C, Beebe W, Bowman CB, Gong X, Corey DR, Mootha VV. Analyzing pre-symptomatic tissue to gain insights into the molecular and mechanistic origins of late-onset degenerative trinucleotide repeat disease. Nucleic Acids Research. PMID 32463444 DOI: 10.1093/nar/gkaa422  1
2020 Shen X, Wong J, Prakash TP, Rigo F, Li Y, Napierala M, Corey DR. Progress towards drug discovery for Friedreich's Ataxia: Identifying synthetic oligonucleotides that more potently activate expression of human frataxin protein. Bioorganic & Medicinal Chemistry. 115472. PMID 32279920 DOI: 10.1016/j.bmc.2020.115472  1
2020 Chau VQ, Hu J, Gong X, Hulleman JD, Ufret-Vincenty RL, Rigo F, Prakash TP, Corey DR, Mootha VV. Delivery of Antisense Oligonucleotides to the Cornea. Nucleic Acid Therapeutics. PMID 32202944 DOI: 10.1089/nat.2019.0838  1
2019 Liu Z, Johnson ST, Zhang Z, Corey DR. Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes. Nucleic Acid Therapeutics. PMID 31670606 DOI: 10.1089/nat.2019.0815  0.8
2019 Hu J, Corey DR. Limits of using oligonucleotides for allele-selective inhibition at trinucleotide repeat sequences - targeting the CAG repeat within ataxin-1. Nucleosides, Nucleotides & Nucleic Acids. 1-10. PMID 31645175 DOI: 10.1080/15257770.2019.1671592  1
2019 Rong Z, Hu J, Corey DR, Mootha VV. Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy. Investigative Ophthalmology & Visual Science. 60: 3980-3991. PMID 31560764 DOI: 10.1167/iovs.19-27641  1
2019 Shen X, Beasley S, Putnam J, Li Y, Prakash T, Rigo F, Napierala M, Corey D. Efficient Electroporation of Neuronal Cells Using Synthetic Oligonucleotides: Identifying Duplex RNA and Antisense Oligonucleotide Activators of Human Frataxin Expression. Rna (New York, N.Y.). PMID 31151992 DOI: 10.1261/rna.071290.119  0.96
2019 Gagnon KT, Corey DR. Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs. Nucleic Acid Therapeutics. PMID 30907681 DOI: 10.1089/nat.2018.0772  1
2019 Hu J, Shen X, Rigo F, Prakash TP, Mootha VV, Corey DR. Duplex RNAs and ss-siRNAs Block RNA Foci Associated with Fuchs' Endothelial Corneal Dystrophy. Nucleic Acid Therapeutics. PMID 30676271 DOI: 10.1089/nat.2018.0764  1
2018 Liu J, Liu Z, Corey DR. The Requirement for GW182 Scaffolding Protein Depends on whether Argonaute is Mediating Translation, Transcription, or Splicing. Biochemistry. PMID 30086238 DOI: 10.1021/acs.biochem.8b00602  1
2018 Shen X, Kilikevicius A, O'Reilly D, Prakash TP, Damha MJ, Rigo F, Corey DR. Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion. Bioorganic & Medicinal Chemistry Letters. PMID 30076049 DOI: 10.1016/j.bmcl.2018.07.033  1
2018 Li L, Shen X, Liu Z, Norrbom M, Prakash TP, O'Reilly D, Sharma VK, Damha MJ, Watts JK, Rigo F, Corey DR. Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat. Nucleic Acid Therapeutics. PMID 29341839 DOI: 10.1089/nat.2017.0703  1
2018 Hu J, Rong Z, Gong X, Zhou Z, Sharma VK, Xing C, Watts JK, Corey DR, Mootha VV. Oligonucleotides Targeting TCF4 Triplet Repeat Expansion Inhibit RNA Foci and Mis-splicing in Fuchs' Dystrophy. Human Molecular Genetics. PMID 29325021 DOI: 10.1093/hmg/ddy018  1
2017 Shen X, Corey DR. Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs. Nucleic Acids Research. PMID 29240946 DOI: 10.1093/nar/gkx1239  0.96
2017 Hicks JA, Li L, Matsui M, Chu Y, Volkov O, Johnson KC, Corey DR. Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription. Cell Reports. 20: 1543-1552. PMID 28813667 DOI: 10.1016/j.celrep.2017.07.058  1
2017 Liu J, Hu J, Ludlow AT, Pham JT, Shay JW, Rothstein JD, Corey DR. c9orf72 Disease-Related Foci Are Each Composed of One Mutant Expanded Repeat RNA. Cell Chemical Biology. PMID 28132891 DOI: 10.1016/j.chembiol.2016.12.018  1
2016 Hu J, Rigo F, Prakash TP, Corey DR. Recognition of c9orf72 Mutant RNA by Single-Stranded Silencing RNAs. Nucleic Acid Therapeutics. PMID 28005462 DOI: 10.1089/nat.2016.0655  1
2016 Matsui M, Corey DR. Non-coding RNAs as drug targets. Nature Reviews. Drug Discovery. PMID 27444227 DOI: 10.1038/nrd.2016.117  1
2016 Liu H, Liang C, Kollipara RK, Matsui M, Ke X, Jeong BC, Wang Z, Yoo KS, Yadav GP, Kinch LN, Grishin NV, Nam Y, Corey DR, Kittler R, Liu Q. HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing. Molecular Cell. PMID 27425409 DOI: 10.1016/j.molcel.2016.06.014  1
2016 Matsui M, Prakash TP, Corey DR. Argonaute 2-dependent Regulation of Gene Expression by Single-stranded miRNA Mimics. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 946-55. PMID 26903376 DOI: 10.1038/mt.2016.39  1
2016 Dodd DW, Tomchick DR, Corey DR, Gagnon KT. Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches. Biochemistry. PMID 26878348 DOI: 10.1021/acs.biochem.6b00136  1
2016 Matsui M, Threlfall RN, Caruthers MH, Corey DR. Effect of 2'-O-methyl/thiophosphonoacetate-modified antisense oligonucleotides on huntingtin expression in patient-derived cells. Artificial Dna, Pna & Xna. 0. PMID 26865404 DOI: 10.1080/1949095X.2016.1146391  1
2016 Li L, Matsui M, Corey DR. Activating frataxin expression by repeat-targeted nucleic acids. Nature Communications. 7: 10606. PMID 26842135 DOI: 10.1038/ncomms10606  1
2016 Kalantari R, Chiang CM, Corey DR. Regulation of mammalian transcription and splicing by Nuclear RNAi. Nucleic Acids Research. 44: 524-37. PMID 26612865 DOI: 10.1093/nar/gkv1305  1
2015 Gagnon KT, Corey DR. Stepping toward therapeutic CRISPR. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644585 DOI: 10.1073/pnas.1521670112  1
2015 Hu J, Liu J, Li L, Gagnon KT, Corey DR. Engineering Duplex RNAs for Challenging Targets: Recognition of GGGGCC/CCCCGG Repeats at the ALS/FTD C9orf72 Locus. Chemistry & Biology. PMID 26584779 DOI: 10.1016/j.chembiol.2015.09.016  1
2015 Matsui M, Li L, Janowski BA, Corey DR. Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors. Scientific Reports. 5: 12855. PMID 26242502 DOI: 10.1038/srep12855  1
2015 Wang T, Xiao G, Chu Y, Zhang MQ, Corey DR, Xie Y. Design and bioinformatics analysis of genome-wide CLIP experiments. Nucleic Acids Research. 43: 5263-74. PMID 25958398 DOI: 10.1093/nar/gkv439  1
2015 Chu Y, Wang T, Dodd D, Xie Y, Janowski BA, Corey DR. Intramolecular circularization increases efficiency of RNA sequencing and enables CLIP-Seq of nuclear RNA from human cells. Nucleic Acids Research. 43: e75. PMID 25813040 DOI: 10.1093/nar/gkv213  1
2015 Liu J, Hu J, Hicks JA, Prakash TP, Corey DR. Modulation of Splicing by Single-Stranded Silencing RNAs. Nucleic Acid Therapeutics. 25: 113-20. PMID 25757055 DOI: 10.1089/nat.2014.0527  1
2015 Younger ST, Corey DR. Identification and validation of miRNA target sites within nontraditional miRNA targets. Methods in Molecular Biology (Clifton, N.J.). 1206: 53-67. PMID 25240886 DOI: 10.1007/978-1-4939-1369-5_5  1
2014 Corey DR, Wise JA, Fox KR, Stoddard BL. Breakthrough articles: putting science first. Nucleic Acids Research. 42: 11273-4. PMID 25301802 DOI: 10.1093/nar/gku853  1
2014 Gagnon KT, Li L, Janowski BA, Corey DR. Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading. Nature Protocols. 9: 2045-60. PMID 25079428 DOI: 10.1038/nprot.2014.135  1
2014 Hu J, Liu J, Narayanannair KJ, Lackey JG, Kuchimanchi S, Rajeev KG, Manoharan M, Swayze EE, Lima WF, Prakash TP, Xiang Q, Martinez C, Corey DR. Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs. Biochemistry. 53: 4510-8. PMID 24981774 DOI: 10.1021/bi500610r  1
2014 Hu J, Liu J, Yu D, Aiba Y, Lee S, Pendergraff H, Boubaker J, Artates JW, Lagier-Tourenne C, Lima WF, Swayze EE, Prakash TP, Corey DR. Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs. Nucleic Acid Therapeutics. 24: 199-209. PMID 24694346 DOI: 10.1089/nat.2013.0476  1
2014 Gagnon KT, Li L, Chu Y, Janowski BA, Corey DR. RNAi factors are present and active in human cell nuclei. Cell Reports. 6: 211-21. PMID 24388755 DOI: 10.1016/j.celrep.2013.12.013  1
2013 Aiba Y, Hu J, Liu J, Xiang Q, Martinez C, Corey DR. Allele-selective inhibition of expression of huntingtin and ataxin-3 by RNA duplexes containing unlocked nucleic acid substitutions. Biochemistry. 52: 9329-38. PMID 24266403 DOI: 10.1021/bi4014209  1
2013 Matsui M, Chu Y, Zhang H, Gagnon KT, Shaikh S, Kuchimanchi S, Manoharan M, Corey DR, Janowski BA. Promoter RNA links transcriptional regulation of inflammatory pathway genes. Nucleic Acids Research. 41: 10086-109. PMID 23999091 DOI: 10.1093/nar/gkt777  1
2013 Liu J, Yu D, Aiba Y, Pendergraff H, Swayze EE, Lima WF, Hu J, Prakash TP, Corey DR. ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy. Nucleic Acids Research. 41: 9570-83. PMID 23935115 DOI: 10.1093/nar/gkt693  1
2013 Liu J, Pendergraff H, Narayanannair KJ, Lackey JG, Kuchimanchi S, Rajeev KG, Manoharan M, Hu J, Corey DR. RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression. Nucleic Acids Research. 41: 8788-801. PMID 23887934 DOI: 10.1093/nar/gkt594  1
2013 Dodd DW, Gagnon KT, Corey DR. Digital quantitation of potential therapeutic target RNAs. Nucleic Acid Therapeutics. 23: 188-94. PMID 23656494 DOI: 10.1089/nat.2013.0427  1
2013 Matsui M, Prakash TP, Corey DR. Transcriptional silencing by single-stranded RNAs targeting a noncoding RNA that overlaps a gene promoter. Acs Chemical Biology. 8: 122-6. PMID 23082936 DOI: 10.1021/cb300490j  1
2012 Hu J, Liu J, Yu D, Chu Y, Corey DR. Mechanism of allele-selective inhibition of huntingtin expression by duplex RNAs that target CAG repeats: function through the RNAi pathway. Nucleic Acids Research. 40: 11270-80. PMID 23042244 DOI: 10.1093/nar/gks907  1
2012 Yu D, Pendergraff H, Liu J, Kordasiewicz HB, Cleveland DW, Swayze EE, Lima WF, Crooke ST, Prakash TP, Corey DR. Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression. Cell. 150: 895-908. PMID 22939619 DOI: 10.1016/j.cell.2012.08.002  1
2012 Chu Y, Corey DR. RNA sequencing: platform selection, experimental design, and data interpretation. Nucleic Acid Therapeutics. 22: 271-4. PMID 22830413 DOI: 10.1089/nat.2012.0367  1
2012 Chu Y, Kalantari R, Dodd DW, Corey DR. Transcriptional silencing by hairpin RNAs complementary to a gene promoter. Nucleic Acid Therapeutics. 22: 147-51. PMID 22703280 DOI: 10.1089/nat.2012.0360  1
2012 Matsui M, Corey DR. Allele-selective inhibition of trinucleotide repeat genes. Drug Discovery Today. 17: 443-50. PMID 22285529 DOI: 10.1016/j.drudis.2012.01.006  1
2012 Gagnon KT, Corey DR. Argonaute and the nuclear RNAs: new pathways for RNA-mediated control of gene expression. Nucleic Acid Therapeutics. 22: 3-16. PMID 22283730 DOI: 10.1089/nat.2011.0330  1
2012 Watts JK, Corey DR. Silencing disease genes in the laboratory and the clinic. The Journal of Pathology. 226: 365-79. PMID 22069063 DOI: 10.1002/path.2993  1
2012 Liu J, Hu J, Corey DR. Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing. Nucleic Acids Research. 40: 1240-50. PMID 21948593 DOI: 10.1093/nar/gkr780  1
2011 Yu D, Sakurai F, Corey DR. Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression. Bioorganic & Medicinal Chemistry Letters. 21: 5202-5. PMID 21840716 DOI: 10.1016/j.bmcl.2011.07.053  1
2011 Peña-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, Wolff NC, Tran TA, Zou L, Xie XJ, Corey DR, Brugarolas J. Regulation of TFEB and V-ATPases by mTORC1. The Embo Journal. 30: 3242-58. PMID 21804531 DOI: 10.1038/emboj.2011.257  1
2011 Schwartz JC, Corey DR. Practical considerations for analyzing antigene RNAs (agRNAs): RNA immunoprecipitation of argonaute protein. Methods in Molecular Biology (Clifton, N.J.). 764: 301-15. PMID 21748649 DOI: 10.1007/978-1-61779-188-8_20  1
2011 Younger ST, Corey DR. Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini. Molecular Biosystems. 7: 2383-8. PMID 21589992 DOI: 10.1039/c1mb05090g  1
2011 Gagnon KT, Watts JK, Pendergraff HM, Montaillier C, Thai D, Potier P, Corey DR. Antisense and antigene inhibition of gene expression by cell-permeable oligonucleotide-oligospermine conjugates. Journal of the American Chemical Society. 133: 8404-7. PMID 21539318 DOI: 10.1021/ja200312y  1
2011 Younger ST, Corey DR. Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters. Nucleic Acids Research. 39: 5682-91. PMID 21427083 DOI: 10.1093/nar/gkr155  1
2011 Hu J, Gagnon KT, Liu J, Watts JK, Syeda-Nawaz J, Bennett CF, Swayze EE, Randolph J, Chattopadhyaya J, Corey DR. Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs. Biological Chemistry. 392: 315-25. PMID 21294677 DOI: 10.1515/BC.2011.045  1
2010 Bosy D, Etlin D, Corey D, Lee JW. An interdisciplinary pain rehabilitation programme: description and evaluation of outcomes. Physiotherapy Canada. PhysiothéRapie Canada. 62: 316-26. PMID 21886371 DOI: 10.3138/physio.62.4.316  0.64
2010 Matsui M, Sakurai F, Elbashir S, Foster DJ, Manoharan M, Corey DR. Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter. Chemistry & Biology. 17: 1344-55. PMID 21168770 DOI: 10.1016/j.chembiol.2010.10.009  1
2010 Hu J, Liu J, Corey DR. Allele-selective inhibition of huntingtin expression by switching to an miRNA-like RNAi mechanism. Chemistry & Biology. 17: 1183-8. PMID 21095568 DOI: 10.1016/j.chembiol.2010.10.013  1
2010 Gagnon KT, Pendergraff HM, Deleavey GF, Swayze EE, Potier P, Randolph J, Roesch EB, Chattopadhyaya J, Damha MJ, Bennett CF, Montaillier C, Lemaitre M, Corey DR. Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat. Biochemistry. 49: 10166-78. PMID 21028906 DOI: 10.1021/bi101208k  1
2010 Chu Y, Yue X, Younger ST, Janowski BA, Corey DR. Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter. Nucleic Acids Research. 38: 7736-48. PMID 20675357 DOI: 10.1093/nar/gkq648  1
2010 Janowski BA, Corey DR. Minireview: Switching on progesterone receptor expression with duplex RNA. Molecular Endocrinology (Baltimore, Md.). 24: 2243-52. PMID 20592161 DOI: 10.1210/me.2010-0067  1
2010 Yue X, Schwartz JC, Chu Y, Younger ST, Gagnon KT, Elbashir S, Janowski BA, Corey DR. Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini. Nature Chemical Biology. 6: 621-9. PMID 20581822 DOI: 10.1038/nchembio.400  1
2010 Wancewicz EV, Maier MA, Siwkowski AM, Albertshofer K, Winger TM, Berdeja A, Gaus H, Vickers TA, Bennett CF, Monia BP, Griffey RH, Nulf CJ, Hu J, Corey DR, Swayze EE, et al. Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue. Journal of Medicinal Chemistry. 53: 3919-26. PMID 20420385 DOI: 10.1021/jm901489k  1
2010 Watts JK, Yu D, Charisse K, Montaillier C, Potier P, Manoharan M, Corey DR. Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters. Nucleic Acids Research. 38: 5242-59. PMID 20403811 DOI: 10.1093/nar/gkq258  1
2010 Watts JK, Corey DR. Clinical status of duplex RNA. Bioorganic & Medicinal Chemistry Letters. 20: 3203-7. PMID 20399650 DOI: 10.1016/j.bmcl.2010.03.109  1
2010 Li Y, Malaeb BS, Li ZZ, Thompson MG, Chen Z, Corey DR, Hsieh JT, Shay JW, Koeneman KS. Telomerase enzyme inhibition (TEI) and cytolytic therapy in the management of androgen independent osseous metastatic prostate cancer. The Prostate. 70: 616-29. PMID 20043297 DOI: 10.1002/pros.21096  1
2009 Corey DR. Telomeres and telomerase: from discovery to clinical trials. Chemistry & Biology. 16: 1219-23. PMID 20064431 DOI: 10.1016/j.chembiol.2009.12.001  1
2009 Hu J, Matsui M, Corey DR. Allele-selective inhibition of mutant huntingtin by peptide nucleic acid-peptide conjugates, locked nucleic acid, and small interfering RNA. Annals of the New York Academy of Sciences. 1175: 24-31. PMID 19796074 DOI: 10.1111/j.1749-6632.2009.04975.x  1
2009 Hu J, Dodd DW, Hudson RH, Corey DR. Cellular localization and allele-selective inhibition of mutant huntingtin protein by peptide nucleic acid oligomers containing the fluorescent nucleobase [bis-o-(aminoethoxy)phenyl]pyrrolocytosine. Bioorganic & Medicinal Chemistry Letters. 19: 6181-4. PMID 19783436 DOI: 10.1016/j.bmcl.2009.09.004  1
2009 Younger ST, Pertsemlidis A, Corey DR. Predicting potential miRNA target sites within gene promoters. Bioorganic & Medicinal Chemistry Letters. 19: 3791-4. PMID 19423343 DOI: 10.1016/j.bmcl.2009.04.032  1
2009 Hu J, Matsui M, Gagnon KT, Schwartz JC, Gabillet S, Arar K, Wu J, Bezprozvanny I, Corey DR. Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs. Nature Biotechnology. 27: 478-84. PMID 19412185 DOI: 10.1038/nbt.1539  1
2009 Younger ST, Corey DR. The puzzle of RNAs that target gene promoters. Chembiochem : a European Journal of Chemical Biology. 10: 1135-9. PMID 19301312 DOI: 10.1002/cbic.200900015  1
2008 Beane R, Gabillet S, Montaillier C, Arar K, Corey DR. Recognition of chromosomal DNA inside cells by locked nucleic acids. Biochemistry. 47: 13147-9. PMID 19053275 DOI: 10.1021/bi801930p  1
2008 Schwartz JC, Younger ST, Nguyen NB, Hardy DB, Monia BP, Corey DR, Janowski BA. Antisense transcripts are targets for activating small RNAs. Nature Structural & Molecular Biology. 15: 842-8. PMID 18604220 DOI: 10.1038/nsmb.1444  1
2007 Corey DR. Chemical modification: the key to clinical application of RNA interference? The Journal of Clinical Investigation. 117: 3615-22. PMID 18060019 DOI: 10.1172/JCI33483  1
2007 Hu J, Corey DR. Inhibiting gene expression with peptide nucleic acid (PNA)--peptide conjugates that target chromosomal DNA. Biochemistry. 46: 7581-9. PMID 17536840 DOI: 10.1021/bi700230a  1
2007 Beane RL, Ram R, Gabillet S, Arar K, Monia BP, Corey DR. Inhibiting gene expression with locked nucleic acids (LNAs) that target chromosomal DNA. Biochemistry. 46: 7572-80. PMID 17536839 DOI: 10.1021/bi700227g  1
2007 Janowski BA, Younger ST, Hardy DB, Ram R, Huffman KE, Corey DR. Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nature Chemical Biology. 3: 166-73. PMID 17259978 DOI: 10.1038/nchembio860  1
2007 Corey DR. RNA learns from antisense. Nature Chemical Biology. 3: 8-11. PMID 17173018 DOI: 10.1038/nchembio0107-8  1
2006 Janowski BA, Hu J, Corey DR. Silencing gene expression by targeting chromosomal DNA with antigene peptide nucleic acids and duplex RNAs. Nature Protocols. 1: 436-43. PMID 17406266 DOI: 10.1038/nprot.2006.64  1
2006 Johnson AA, Sayer JM, Yagi H, Patil SS, Debart F, Maier MA, Corey DR, Vasseur JJ, Burke TR, Marquez VE, Jerina DM, Pommier Y. Effect of DNA modifications on DNA processing by HIV-1 integrase and inhibitor binding: role of DNA backbone flexibility and an open catalytic site. The Journal of Biological Chemistry. 281: 32428-38. PMID 16943199 DOI: 10.1074/jbc.M605101200  1
2006 Janowski BA, Huffman KE, Schwartz JC, Ram R, Nordsell R, Shames DS, Minna JD, Corey DR. Involvement of AGO1 and AGO2 in mammalian transcriptional silencing. Nature Structural & Molecular Biology. 13: 787-92. PMID 16936728 DOI: 10.1038/nsmb1140  1
2006 Hardy DB, Janowski BA, Corey DR, Mendelson CR. Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-kappaB activation of cyclooxygenase 2 expression. Molecular Endocrinology (Baltimore, Md.). 20: 2724-33. PMID 16772530 DOI: 10.1210/me.2006-0112  1
2006 Corey DR. EuroTIDES 2005--Sixth Annual IBC Conference. Oligonucleotide, RNAi and peptides for the drug development and manufacturing industry. Idrugs : the Investigational Drugs Journal. 9: 105-6. PMID 16523398  1
2006 Canales BK, Li Y, Thompson MG, Gleason JM, Chen Z, Malaeb B, Corey DR, Herbert BS, Shay JW, Koeneman KS. Small molecule, oligonucleotide-based telomerase template inhibition in combination with cytolytic therapy in an in vitro androgen-independent prostate cancer model. Urologic Oncology. 24: 141-51. PMID 16520278 DOI: 10.1016/j.urolonc.2005.11.003  1
2005 Janowski BA, Corey DR. Inhibiting transcription of chromosomal DNA using antigene RNAs. Nucleic Acids Symposium Series (2004). 367-8. PMID 17150786 DOI: 10.1093/nass/49.1.367  1
2005 Janowski BA, Huffman KE, Schwartz JC, Ram R, Hardy D, Shames DS, Minna JD, Corey DR. Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs. Nature Chemical Biology. 1: 216-22. PMID 16408038 DOI: 10.1038/nchembio725  1
2005 Janowski BA, Kaihatsu K, Huffman KE, Schwartz JC, Ram R, Hardy D, Mendelson CR, Corey DR. Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids. Nature Chemical Biology. 1: 210-5. PMID 16408037 DOI: 10.1038/nchembio724  1
2005 Corey DR. Recognition of chromosomal DNA in human cells by peptide nucleic acids and small duplex RNAs. Annals of the New York Academy of Sciences. 1058: 16-25. PMID 16394122 DOI: 10.1196/annals.1359.003  1
2005 Corey DR. Regulating mammalian transcription with RNA. Trends in Biochemical Sciences. 30: 655-8. PMID 16226463 DOI: 10.1016/j.tibs.2005.09.007  1
2005 Corey DR. Calcium liberates PNAs from endosomes. Chemistry & Biology. 12: 864-5. PMID 16125097 DOI: 10.1016/j.chembiol.2005.08.003  1
2005 Huffman KE, Corey DR. Major vault protein does not play a role in chemoresistance or drug localization in a non-small cell lung cancer cell line. Biochemistry. 44: 2253-61. PMID 15709737 DOI: 10.1021/bi047948g  1
2004 Natarajan S, Chen Z, Wancewicz EV, Monia BP, Corey DR. Telomerase reverse transcriptase (hTERT) mRNA and telomerase RNA (hTR) as targets for downregulation of telomerase activity. Oligonucleotides. 14: 263-73. PMID 15665594 DOI: 10.1089/oli.2004.14.263  1
2004 Kaihatsu K, Huffman KE, Corey DR. Intracellular uptake and inhibition of gene expression by PNAs and PNA-peptide conjugates. Biochemistry. 43: 14340-7. PMID 15533038 DOI: 10.1021/bi048519l  1
2004 Paroo Z, Bollinger RA, Braasch DA, Richer E, Corey DR, Antich PP, Mason RP. Validating bioluminescence imaging as a high-throughput, quantitative modality for assessing tumor burden. Molecular Imaging. 3: 117-24. PMID 15296676 DOI: 10.1162/1535350041464865  1
2004 Paroo Z, Corey DR. Challenges for RNAi in vivo. Trends in Biotechnology. 22: 390-4. PMID 15283982 DOI: 10.1016/j.tibtech.2004.06.004  1
2004 Nulf CJ, Corey D. Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs). Nucleic Acids Research. 32: 3792-8. PMID 15263060 DOI: 10.1093/nar/gkh706  0.76
2004 Kaihatsu K, Janowski BA, Corey DR. Recognition of chromosomal DNA by PNAs. Chemistry & Biology. 11: 749-58. PMID 15217608 DOI: 10.1016/j.chembiol.2003.09.014  1
2004 Kaihatsu K, Corey DR. Synthesis of peptide nucleic acid-peptide conjugates. Methods in Molecular Biology (Clifton, N.J.). 283: 207-14. PMID 15197312 DOI: 10.1385/1-59259-813-7:207  1
2004 Corey DR. Synthesis of oligonucleotide-peptide and oligonucleotide-protein conjugates. Methods in Molecular Biology (Clifton, N.J.). 283: 197-206. PMID 15197311 DOI: 10.1385/1-59259-813-7:197  1
2004 Braasch DA, Paroo Z, Constantinescu A, Ren G, Oz OK, Mason RP, Corey DR. Biodistribution of phosphodiester and phosphorothioate siRNA. Bioorganic & Medicinal Chemistry Letters. 14: 1139-43. PMID 14980652 DOI: 10.1016/j.bmcl.2003.12.074  1
2004 Liu Y, Braasch DA, Nulf CJ, Corey DR. Efficient and isoform-selective inhibition of cellular gene expression by peptide nucleic acids. Biochemistry. 43: 1921-7. PMID 14967032 DOI: 10.1021/bi0358519  1
2003 Kaihatsu K, Shah RH, Zhao X, Corey DR. Extending recognition by peptide nucleic acids (PNAs): binding to duplex DNA and inhibition of transcription by tail-clamp PNA-peptide conjugates. Biochemistry. 42: 13996-4003. PMID 14636068 DOI: 10.1021/bi035194k  1
2003 Liu B, Han Y, Ferdous A, Corey DR, Kodadek T. Transcription activation by a PNA-peptide chimera in a mammalian cell extract. Chemistry & Biology. 10: 909-16. PMID 14583257 DOI: 10.1016/j.chembiol.2003.09.008  1
2003 Zhao X, Kaihatsu K, Corey DR. Inhibition of transcription by bisPNA-peptide conjugates. Nucleosides, Nucleotides & Nucleic Acids. 22: 535-46. PMID 14565228 DOI: 10.1081/NCN-120021953  1
2003 Paroo Z, Corey DR. Imaging gene expression using oligonucleotides and peptide nucleic acids. Journal of Cellular Biochemistry. 90: 437-42. PMID 14523977 DOI: 10.1002/jcb.10626  1
2003 Chen Z, Koeneman KS, Corey DR. Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells. Cancer Research. 63: 5917-25. PMID 14522918  1
2003 Braasch DA, Jensen S, Liu Y, Kaur K, Arar K, White MA, Corey DR. RNA interference in mammalian cells by chemically-modified RNA. Biochemistry. 42: 7967-75. PMID 12834349 DOI: 10.1021/bi0343774  1
2003 Bergstrom RC, Coombs GS, Ye S, Madison EL, Goldsmith EJ, Corey DR. Binding of nonphysiological protein and peptide substrates to proteases: differences between urokinase-type plasminogen activator and trypsin and contributions to the evolution of regulated proteolysis. Biochemistry. 42: 5395-402. PMID 12731881 DOI: 10.1021/bi027417x  1
2003 Barma DK, Elayadi A, Falck JR, Corey DR. Inhibition of telomerase by BIBR 1532 and related analogues. Bioorganic & Medicinal Chemistry Letters. 13: 1333-6. PMID 12657276 DOI: 10.1016/S0960-894X(03)00101-X  1
2003 Chen Z, Corey DR. Telomerase inhibitors: a new option for chemotherapy. Advances in Cancer Research. 87: 31-58. PMID 12641273 DOI: 10.1016/S0065-230X(03)87173-7  1
2003 Gamper HB, Nulf CJ, Corey DR, Kmiec EB. The synaptic complex of RecA protein participates in hybridization and inverse strand exchange reactions. Biochemistry. 42: 2643-55. PMID 12614159 DOI: 10.1021/bi0205202  1
2002 Braasch DA, Corey DR. Cellular delivery of locked nucleic acids (LNAs). Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 4.13. PMID 18428895 DOI: 10.1002/0471142700.nc0413s09  1
2002 Braasch DA, Nulf CJ, Corey DR. Synthesis and purification of peptide nucleic acids. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 4.11. PMID 18428893 DOI: 10.1002/0471142700.nc0411s09  1
2002 Braasch DA, Liu Y, Corey DR. Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design. Nucleic Acids Research. 30: 5160-7. PMID 12466540 DOI: 10.1093/nar/gkf651  1
2002 Chen Z, Monia BP, Corey DR. Telomerase inhibition, telomere shortening, and decreased cell proliferation by cell permeable 2'-O-methoxyethyl oligonucleotides. Journal of Medicinal Chemistry. 45: 5423-5. PMID 12459009 DOI: 10.1021/jm025563v  1
2002 Braasch DA, Corey DR. Lipid-mediated introduction of peptide nucleic acids into cells. Methods in Molecular Biology (Clifton, N.J.). 208: 211-23. PMID 12229290 DOI: 10.1385/1-59259-290-2:211  1
2002 Kaihatsu K, Braasch DA, Cansizoglu A, Corey DR. Enhanced strand invasion by peptide nucleic acid-peptide conjugates. Biochemistry. 41: 11118-25. PMID 12220176 DOI: 10.1021/bi0263659  1
2002 Elayadi AN, Braasch DA, Corey DR. Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase. Biochemistry. 41: 9973-81. PMID 12146961 DOI: 10.1021/bi025907j  1
2002 Lee HJ, Boado RJ, Braasch DA, Corey DR, Pardridge WM. Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington's disease with an antisense radiopharmaceutical and drug-targeting technology. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 43: 948-56. PMID 12097468  1
2002 Nulf CJ, Corey DR. DNA assembly using bis-peptide nucleic acids (bisPNAs). Nucleic Acids Research. 30: 2782-9. PMID 12087161  1
2002 Braasch DA, Corey DR. Novel antisense and peptide nucleic acid strategies for controlling gene expression. Biochemistry. 41: 4503-10. PMID 11926811 DOI: 10.1021/bi0122112  1
2002 Liu B, Han Y, Corey DR, Kodadek T. Toward synthetic transcription activators: recruitment of transcription factors to DNA by a PNA-peptide chimera. Journal of the American Chemical Society. 124: 1838-9. PMID 11866581 DOI: 10.1021/ja0164226  1
2002 Corey DR. Telomerase inhibition, oligonucleotides, and clinical trials. Oncogene. 21: 631-7. PMID 11850789 DOI: 10.1038/sj.onc.1205063  1
2002 Tackett AJ, Corey DR, Raney KD. Non-Watson-Crick interactions between PNA and DNA inhibit the ATPase activity of bacteriophage T4 Dda helicase. Nucleic Acids Research. 30: 950-7. PMID 11842106  1
2001 Doyle DF, Braasch DA, Jackson LK, Weiss HE, Boehm MF, Mangelsdorf DJ, Corey DR. Engineering orthogonal ligand-receptor pairs from "near drugs". Journal of the American Chemical Society. 123: 11367-71. PMID 11707111 DOI: 10.1021/ja0164632  1
2001 Elayadi AN, Corey DR. Application of PNA and LNA oligomers to chemotherapy. Current Opinion in Investigational Drugs (London, England : 2000). 2: 558-61. PMID 11566018  1
2001 Elayadi AN, Demieville A, Wancewicz EV, Monia BP, Corey DR. Inhibition of telomerase by 2'-O-(2-methoxyethyl) RNA oligomers: effect of length, phosphorothioate substitution and time inside cells. Nucleic Acids Research. 29: 1683-9. PMID 11292840  1
2001 Doyle DF, Braasch DA, Simmons CG, Janowski BA, Corey DR. Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length. Biochemistry. 40: 53-64. PMID 11141056 DOI: 10.1021/bi0020630  1
2000 Zhang X, Ishihara T, Corey DR. Strand invasion by mixed base PNAs and a PNA-peptide chimera. Nucleic Acids Research. 28: 3332-8. PMID 10954602  1
2000 Hervio LS, Coombs GS, Bergstrom RC, Trivedi K, Corey DR, Madison EL. Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates. Chemistry & Biology. 7: 443-53. PMID 10873836 DOI: 10.1016/S1074-5521(00)00125-3  1
2000 Doyle DF, Mangelsdorf DJ, Corey DR. Modifying ligand specificity of gene regulatory proteins. Current Opinion in Chemical Biology. 4: 60-3. PMID 10679376 DOI: 10.1016/S1367-5931(99)00052-6  1
1999 Ishihara T, Corey DR. Strand invasion by DNA-peptide conjugates and peptide nucleic acids. Nucleic Acids Symposium Series. 141-2. PMID 10780419  1
1998 Coombs GS, Bergstrom RC, Pellequer JL, Baker SI, Navre M, Smith MM, Tainer JA, Madison EL, Corey DR. Substrate specificity of prostate-specific antigen (PSA). Chemistry & Biology. 5: 475-88. PMID 9751643 DOI: 10.1016/S1074-5521(98)90004-7  1
1998 Doyle DF, Corey DR. Engineering proteins: keeping up with biology. Chemistry & Biology. 5: R157-60. PMID 9662511  1
1998 Peet DJ, Doyle DF, Corey DR, Mangelsdorf DJ. Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR. Chemistry & Biology. 5: 13-21. PMID 9479476  1
1998 Coombs GS, Bergstrom RC, Madison EL, Corey DR. Directing sequence-specific proteolysis to new targets. The influence of loop size and target sequence on selective proteolysis by tissue-type plasminogen activator and urokinase-type plasminogen activator. The Journal of Biological Chemistry. 273: 4323-8. PMID 9468480 DOI: 10.1074/jbc.273.8.4323  1
1997 Ke SH, Coombs GS, Tachias K, Corey DR, Madison EL. Optimal subsite occupancy and design of a selective inhibitor of urokinase. The Journal of Biological Chemistry. 272: 20456-62. PMID 9252355 DOI: 10.1074/jbc.272.33.20456  1
1997 Ke SH, Coombs GS, Tachias K, Navre M, Corey DR, Madison EL. Distinguishing the specificities of closely related proteases. Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase. The Journal of Biological Chemistry. 272: 16603-9. PMID 9195973 DOI: 10.1074/jbc.272.26.16603  1
1996 Smulevitch SV, Simmons CG, Norton JC, Wise TW, Corey DR. Enhancement of strand invasion by oligonucleotides through manipulation of backbone charge. Nature Biotechnology. 14: 1700-4. PMID 9634855 DOI: 10.1038/nbt1296-1700  1
1996 Coombs GS, Dang AT, Madison EL, Corey DR. Distinct mechanisms contribute to stringent substrate specificity of tissue-type plasminogen activator. The Journal of Biological Chemistry. 271: 4461-7. PMID 8626799 DOI: 10.1074/jbc.271.8.4461  1
1995 Madison EL, Coombs GS, Corey DR. Substrate specificity of tissue type plasminogen activator. Characterization of the fibrin independent specificity of t-PA for plasminogen. The Journal of Biological Chemistry. 270: 7558-62. PMID 7706303  1
1995 Ding L, Coombs GS, Strandberg L, Navre M, Corey DR, Madison EL. Origins of the specificity of tissue-type plasminogen activator. Proceedings of the National Academy of Sciences of the United States of America. 92: 7627-31. PMID 7644467 DOI: 10.1073/pnas.92.17.7627  1
1995 Corey DR, Willett WS, Coombs GS, Craik CS. Trypsin specificity increased through substrate-assisted catalysis. Biochemistry. 34: 11521-7. PMID 7547882  1
1990 Pei D, Corey DR, Schultz PG. Site-specific cleavage of duplex DNA by a semisynthetic nuclease via triple-helix formation. Proceedings of the National Academy of Sciences of the United States of America. 87: 9858-62. PMID 2124705 DOI: 10.1073/pnas.87.24.9858  1
1989 Corey DR, Schultz PG. Introduction of a metal-dependent regulatory switch into an enzyme. The Journal of Biological Chemistry. 264: 3666-9. PMID 2917969  1
1989 Corey DR, Pei D, Schultz PG. Generation of a catalytic sequence-specific hybrid DNase. Biochemistry. 28: 8277-86. PMID 2605184 DOI: 10.1021/bi00447a004  1
1987 Corey DR, Schultz PG. Generation of a hybrid sequence-specific single-stranded deoxyribonuclease. Science (New York, N.Y.). 238: 1401-3. PMID 3685986 DOI: 10.1126/science.3685986  1
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