Anna Dubrovska - Publications

Affiliations: 
2007- Scripps Research Institute 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Seifert M, Peitzsch C, Gorodetska I, Börner C, Klink B, Dubrovska A. Network-based analysis of prostate cancer cell lines reveals novel marker gene candidates associated with radioresistance and patient relapse. Plos Computational Biology. 15: e1007460. PMID 31682594 DOI: 10.1371/journal.pcbi.1007460  0.92
2019 Cirillo G, Peitzsch C, Vittorio O, Curcio M, Farfalla A, Voli F, Dubrovska A, Iemma F, Kavallaris M, Hampel S. When polymers meet carbon nanostructures: expanding horizons in cancer therapy. Future Medicinal Chemistry. 11: 2205-2231. PMID 31538523 DOI: 10.4155/fmc-2018-0540  0.92
2019 Digomann D, Linge A, Dubrovska A. SLC3A2/CD98hc, autophagy and tumor radioresistance: a link confirmed. Autophagy. 1-2. PMID 31276435 DOI: 10.1080/15548627.2019.1639302  0.48
2019 Gorodetska I, Kozeretska I, Dubrovska A. Genes: The Role in Genome Stability, Cancer Stemness and Therapy Resistance. Journal of Cancer. 10: 2109-2127. PMID 31205572 DOI: 10.7150/jca.30410  0.92
2019 Peitzsch C, Nathansen J, Schniewind SI, Schwarz F, Dubrovska A. Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma: Identification, Characterization and Clinical Implications. Cancers. 11. PMID 31052565 DOI: 10.3390/cancers11050616  0.92
2019 Gorodetska I, Lukiyanchuk V, Peitzsch C, Kozeretska I, Dubrovska A. BRCA1 and EZH2 cooperate in regulation of prostate cancer stem cell phenotype. International Journal of Cancer. PMID 30968962 DOI: 10.1002/ijc.32323  0.92
2019 Peitzsch C, Kurth I, Ebert N, Dubrovska A, Baumann M. Cancer stem cells in radiation response: current views and future perspectives in radiation oncology. International Journal of Radiation Biology. 1-42. PMID 30897014 DOI: 10.1080/09553002.2019.1589023  0.92
2019 Digomann D, Kurth I, Tyutyunnykova A, Chen O, Löck S, Gorodetska I, Peitzsch C, Skvortsova I, Negro G, Aschenbrenner B, Eisenhofer G, Richter S, Heiden S, Porrmann J, Klink B, ... ... Dubrovska A, et al. The CD98 heavy chain is a marker and regulator of head and neck squamous cell carcinoma radiosensitivity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30670494 DOI: 10.1158/1078-0432.CCR-18-2951  0.92
2018 Lerra L, Farfalla A, Sanz B, Cirillo G, Vittorio O, Voli F, Le Grand M, Curcio M, Nicoletta FP, Dubrovska A, Hampel S, Iemma F, Goya GF. Graphene Oxide Functional Nanohybrids with Magnetic Nanoparticles for Improved Vectorization of Doxorubicin to Neuroblastoma Cells. Pharmaceutics. 11. PMID 30583524 DOI: 10.3390/pharmaceutics11010003  0.4
2017 Tyutyunnykova A, Telegeev G, Dubrovska A. The controversial role of phospholipase C epsilon (PLCε) in cancer development and progression. Journal of Cancer. 8: 716-729. PMID 28382133 DOI: 10.7150/jca.17779  0.84
2017 Peitzsch C, Tyutyunnykova A, Pantel K, Dubrovska A. Cancer stem cells: the root of tumor recurrence and metastasis. Seminars in Cancer Biology. PMID 28257956 DOI: 10.1016/j.semcancer.2017.02.011  0.92
2017 Vittorio O, Curcio M, Cojoc M, Goya GF, Hampel S, Iemma F, Dubrovska A, Cirillo G. Polyphenols delivery by polymeric materials: challenges in cancer treatment. Drug Delivery. 24: 162-180. PMID 28156178 DOI: 10.1080/10717544.2016.1236846  0.8
2016 Kunz-Schughart LA, Dubrovska A, Peitzsch C, Ewe A, Aigner A, Schellenburg S, Muders MH, Hampel S, Cirillo G, Iemma F, Tietze R, Alexiou C, Stephan H, Zarschler K, Vittorio O, et al. Nanoparticles for radiooncology: Mission, vision, challenges. Biomaterials. 120: 155-184. PMID 28063356 DOI: 10.1016/j.biomaterials.2016.12.010  0.92
2016 Linge A, Lohaus F, Löck S, Nowak A, Gudziol V, Valentini C, von Neubeck C, Jütz M, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Grosu AL, ... ... Dubrovska A, et al. HPV status, cancer stem cell marker expression, hypoxia gene signatures and tumour volume identify good prognosis subgroups in patients with HNSCC after primary radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG). Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 27913065 DOI: 10.1016/j.radonc.2016.11.008  0.8
2016 Zscheppang K, Kurth I, Wachtel N, Dubrovska A, Kunz-Schughart LA, Cordes N. Efficacy of Beta1 Integrin and EGFR Targeting in Sphere-Forming Human Head and Neck Cancer Cells. Journal of Cancer. 7: 736-45. PMID 27076856 DOI: 10.7150/jca.14232  0.8
2016 Peitzsch C, Cojoc M, Hein L, Kurth I, Mӓbert K, Trautmann F, Klink B, Schrock E, Wirth MP, Krause M, Stakhovsky EA, Telegeev GD, Novotny V, Toma MI, Muders M, ... ... Dubrovska A, et al. An epigenetic reprogramming strategy to re-sensitize radioresistant prostate cancer cells. Cancer Research. PMID 26984757 DOI: 10.1158/0008-5472.CAN-15-2116  0.96
2016 Krause M, Dubrovska A, Linge A, Baumann M. Cancer stem cells: Radioresistance, prediction of radiotherapy outcome and specific targets for combined treatments. Advanced Drug Delivery Reviews. PMID 26877102 DOI: 10.1016/j.addr.2016.02.002  0.8
2016 Linge A, Lock S, Gudziol V, Nowak A, Lohaus F, von Neubeck C, Jutz M, Abdollahi A, Debus J, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rodel C, ... ... Dubrovska A, et al. Low CSC marker expression and low hypoxia identify good prognosis subgroups in HPV(-)HNSCC after postoperative radiochemotherapy: a multicenter study of the DKTK-ROG. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26755529 DOI: 10.1158/1078-0432.CCR-15-1990  0.8
2015 Kurth I, Hein L, Mäbert K, Peitzsch C, Koi L, Cojoc M, Kunz-Schughart L, Baumann M, Dubrovska A. Cancer stem cell related markers of radioresistance in head and neck squamous cell carcinoma. Oncotarget. PMID 26460734 DOI: 10.18632/oncotarget.5417  0.96
2015 Kuhlmann JD, Hein L, Kurth I, Wimberger P, Dubrovska A. Targeting cancer stem cells: promises and challenges. Anti-Cancer Agents in Medicinal Chemistry. PMID 26179271  0.96
2015 Castro Nava A, Cojoc M, Peitzsch C, Cirillo G, Kurth I, Fuessel S, Erdmann K, Kunhardt D, Vittorio O, Hampel S, Dubrovska A. Development of novel radiochemotherapy approaches targeting prostate tumor progenitor cells using nanohybrids. International Journal of Cancer. 137: 2492-503. PMID 26059723 DOI: 10.1002/ijc.29614  0.92
2015 Cojoc M, Peitzsch C, Kurth I, Trautmann F, Kunz-Schughart LA, Telegeev GD, Stakhovsky EA, Walker JR, Simin K, Lyle S, Fuessel S, Erdmann K, Wirth MP, Krause M, Baumann M, ... Dubrovska A, et al. Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells. Cancer Research. 75: 1482-94. PMID 25670168 DOI: 10.1158/0008-5472.CAN-14-1924  0.96
2015 Cojoc M, Mäbert K, Muders MH, Dubrovska A. A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms. Seminars in Cancer Biology. 31: 16-27. PMID 24956577 DOI: 10.1016/j.semcancer.2014.06.004  0.8
2014 Masjkur J, Arps-Forker C, Poser SW, Nikolakopoulou P, Toutouna L, Chenna R, Chavakis T, Chatzigeorgiou A, Chen LS, Dubrovska A, Choudhary P, Uphues I, Mark M, Bornstein SR, Androutsellis-Theotokis A. Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release. The Journal of Biological Chemistry. 289: 35503-16. PMID 25371201 DOI: 10.1074/jbc.M114.590687  0.96
2014 Peitzsch C, Perrin R, Hill RP, Dubrovska A, Kurth I. Hypoxia as a biomarker for radioresistant cancer stem cells. International Journal of Radiation Biology. 90: 636-52. PMID 24844374 DOI: 10.3109/09553002.2014.916841  0.92
2014 Trautmann F, Cojoc M, Kurth I, Melin N, Bouchez LC, Dubrovska A, Peitzsch C. CXCR4 as biomarker for radioresistant cancer stem cells. International Journal of Radiation Biology. 90: 687-99. PMID 24650104 DOI: 10.3109/09553002.2014.906766  0.92
2014 Mäbert K, Cojoc M, Peitzsch C, Kurth I, Souchelnytskyi S, Dubrovska A. Cancer biomarker discovery: current status and future perspectives. International Journal of Radiation Biology. 90: 659-77. PMID 24524284 DOI: 10.3109/09553002.2014.892229  0.92
2014 Economopoulou M, Masjkur J, Raiskup F, Ebermann D, Saha S, Karl MO, Funk R, Jaszai J, Chavakis T, Ehrhart-Bornstein M, Pillunat LE, Kunz-Schughart L, Kurth I, Dubrovska A, Androutsellis-Theotokis A. Expression of the transcription factor Hes3 in the mouse and human ocular surface, and in pterygium. International Journal of Radiation Biology. 90: 700-9. PMID 24512568 DOI: 10.3109/09553002.2014.892228  0.8
2013 Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, Zhou Q, Dubrovska A, Biroc SL, Marsden R, Pinstaff J, Smider VV, Schultz PG. Bispecific small molecule-antibody conjugate targeting prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: 17796-801. PMID 24127589 DOI: 10.1073/pnas.1316026110  0.96
2013 Cojoc M, Peitzsch C, Trautmann F, Polishchuk L, Telegeev GD, Dubrovska A. Emerging targets in cancer management: role of the CXCL12/CXCR4 axis. Oncotargets and Therapy. 6: 1347-61. PMID 24124379 DOI: 10.2147/OTT.S36109  0.92
2013 Bütof R, Dubrovska A, Baumann M. Clinical perspectives of cancer stem cell research in radiation oncology. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 108: 388-96. PMID 23830466 DOI: 10.1016/j.radonc.2013.06.002  0.8
2013 Peitzsch C, Kurth I, Kunz-Schughart L, Baumann M, Dubrovska A. Discovery of the cancer stem cell related determinants of radioresistance. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 108: 378-87. PMID 23830195 DOI: 10.1016/j.radonc.2013.06.003  0.92
2013 Zakharchenko O, Cojoc M, Dubrovska A, Souchelnytskyi S. A role of TGFß1 dependent 14-3-3σ phosphorylation at Ser69 and Ser74 in the regulation of gene transcription, stemness and radioresistance. Plos One. 8: e65163. PMID 23741479 DOI: 10.1371/journal.pone.0065163  0.8
2013 Kim S, Dubrovska A, Salamone RJ, Walker JR, Grandinetti KB, Bonamy GM, Orth AP, Elliott J, Porta DG, Garcia-Echeverria C, Reddy VA. FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells. Plos One. 8: e51671. PMID 23300950 DOI: 10.1371/journal.pone.0051671  0.96
2012 Dubrovska A, Hartung A, Bouchez LC, Walker JR, Reddy VA, Cho CY, Schultz PG. CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling. British Journal of Cancer. 107: 43-52. PMID 22644306 DOI: 10.1038/bjc.2012.105  0.96
2012 Kim CH, Axup JY, Dubrovska A, Kazane SA, Hutchins BA, Wold ED, Smider VV, Schultz PG. Synthesis of bispecific antibodies using genetically encoded unnatural amino acids. Journal of the American Chemical Society. 134: 9918-21. PMID 22642368 DOI: 10.1021/ja303904e  0.96
2012 Dubrovska A, Elliott J, Salamone RJ, Telegeev GD, Stakhovsky AE, Schepotin IB, Yan F, Wang Y, Bouchez LC, Kularatne SA, Watson J, Trussell C, Reddy VA, Cho CY, Schultz PG. CXCR4 expression in prostate cancer progenitor cells. Plos One. 7: e31226. PMID 22359577 DOI: 10.1371/journal.pone.0031226  0.96
2011 Dubrovska A, Kim C, Elliott J, Shen W, Kuo TH, Koo DI, Li C, Tuntland T, Chang J, Groessl T, Wu X, Gorney V, Ramirez-Montagut T, Spiegel DA, Cho CY, et al. A chemically induced vaccine strategy for prostate cancer. Acs Chemical Biology. 6: 1223-31. PMID 21936526 DOI: 10.1021/cb200222s  0.96
2010 Dubrovska A, Elliott J, Salamone RJ, Kim S, Aimone LJ, Walker JR, Watson J, Sauveur-Michel M, Garcia-Echeverria C, Cho CY, Reddy VA, Schultz PG. Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5692-702. PMID 21138868 DOI: 10.1158/1078-0432.CCR-10-1601  0.96
2010 Miroshnychenko D, Dubrovska A, Maliuta S, Telegeev G, Aspenström P. Novel role of pleckstrin homology domain of the Bcr-Abl protein: analysis of protein-protein and protein-lipid interactions. Experimental Cell Research. 316: 530-42. PMID 19944685 DOI: 10.1016/j.yexcr.2009.11.014  0.56
2009 Dubrovska A, Kim S, Salamone RJ, Walker JR, Maira SM, García-Echeverría C, Schultz PG, Reddy VA. The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proceedings of the National Academy of Sciences of the United States of America. 106: 268-73. PMID 19116269 DOI: 10.1073/pnas.0810956106  0.96
2006 Iwahana H, Yakymovych I, Dubrovska A, Hellman U, Souchelnytskyi S. Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis. Proteomics. 6: 6168-80. PMID 17080483 DOI: 10.1002/pmic.200600384  0.64
2006 Souchelnytskyi S, Lomnytska M, Dubrovska A, Hellman U, Volodko N. Proteomics success story. Towards early detection of breast and ovarian cancer: plasma proteomics as a tool to find novel markers. Proteomics. 6: 65-8. PMID 17031801 DOI: 10.1002/pmic.200600462  0.64
2006 Lomnytska M, Dubrovska A, Hellman U, Volodko N, Souchelnytskyi S. Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients. International Journal of Cancer. 118: 412-21. PMID 16049973 DOI: 10.1002/ijc.21332  0.64
2005 Dubrovska A, Souchelnytskyi S. Efficient enrichment of intact phosphorylated proteins by modified immobilized metal-affinity chromatography. Proteomics. 5: 4678-83. PMID 16252304 DOI: 10.1002/pmic.200500002  0.64
2005 Stasyk T, Dubrovska A, Lomnytska M, Yakymovych I, Wernstedt C, Heldin CH, Hellman U, Souchelnytskyi S. Phosphoproteome profiling of transforming growth factor (TGF)-beta signaling: abrogation of TGFbeta1-dependent phosphorylation of transcription factor-II-I (TFII-I) enhances cooperation of TFII-I and Smad3 in transcription. Molecular Biology of the Cell. 16: 4765-80. PMID 16055503 DOI: 10.1091/mbc.E05-03-0257  0.64
2005 Dubrovska A, Kanamoto T, Lomnytska M, Heldin CH, Volodko N, Souchelnytskyi S. TGFbeta1/Smad3 counteracts BRCA1-dependent repair of DNA damage. Oncogene. 24: 2289-97. PMID 15735739 DOI: 10.1038/sj.onc.1208443  0.64
2004 Grimsby S, Jaensson H, Dubrovska A, Lomnytska M, Hellman U, Souchelnytskyi S. Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity. Febs Letters. 577: 93-100. PMID 15527767 DOI: 10.1016/j.febslet.2004.09.069  0.64
2004 Telegeev GD, Dubrovska AN, Dybkov MV, Maliuta SS. Influence of BCR/ABL fusion proteins on the course of Ph leukemias. Acta Biochimica Polonica. 51: 845-9. PMID 15448745  0.68
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